Basic Information
Gene ID ENSFCAG00000023560
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Felis catus [9685]

Cross Reference
UniProt M3XBG9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSFCAP00000023973 Gene3D G3DSA:1.10.10.60 IPR009057 58 135 4.60e-26 Homeodomain-like
ENSFCAP00000023973 Pfam PF00046 IPR001356 78 134 3.40e-22 Homeobox domain
ENSFCAP00000023973 Pfam PF10525 IPR019549 135 161 1.10e-17 Homeobox engrailed, C-terminal
ENSFCAP00000023973 PRINTS PR00024 IPR020479 114 124 4.60e-07 Homeodomain, metazoa
ENSFCAP00000023973 PRINTS PR00024 IPR020479 124 133 4.60e-07 Homeodomain, metazoa
ENSFCAP00000023973 PRINTS PR00024 IPR020479 99 110 4.60e-07 Homeodomain, metazoa
ENSFCAP00000023973 PRINTS PR00026 IPR000747 139 156 2.60e-18 Homeodomain engrailed
ENSFCAP00000023973 PRINTS PR00026 IPR000747 76 93 2.60e-18 Homeodomain engrailed
ENSFCAP00000023973 PRINTS PR00031 IPR000047 106 115 7.90e-05 Helix-turn-helix motif
ENSFCAP00000023973 PRINTS PR00031 IPR000047 115 131 7.90e-05 Helix-turn-helix motif
ENSFCAP00000023973 ProSitePatterns PS00027 IPR017970 110 133 - Homeobox, conserved site
ENSFCAP00000023973 ProSitePatterns PS00033 IPR019737 146 153 - Homeobox engrailed-type, conserved site
ENSFCAP00000023973 ProSiteProfiles PS50071 IPR001356 75 135 0.00e-00 Homeobox domain
ENSFCAP00000023973 SMART SM00389 IPR001356 77 139 7.10e-28 Homeobox domain
ENSFCAP00000023973 SUPERFAMILY SSF46689 IPR009057 73 135 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSFCAP00000023973 PF00046 2.3e-22 Homeobox Homeobox domain
ENSFCAP00000023973 PF10525 4.9e-18 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSFCAP00000023973 GO:0005634 cellular_component nucleus
ENSFCAP00000023973 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100581025 30195 Bombus terrestris 100649797
8128 Oreochromis niloticus 100706716 132113 Bombus impatiens 100743858
143995 Megachile rotundata 100882481 34638 Metaseiulus occidentalis 100908620
30611 Otolemur garnettii 100946410 9597 Pan paniscus 100996220
9555 Papio anubis 101019723 7897 Latimeria chalumnae 102360063
7227 Drosophila melanogaster 36240 7719 Ciona intestinalis 445653
9544 Macaca mulatta 716307 7460 Apis mellifera 725151
9615 Canis familiaris ENSCAFG00000005082 9483 Callithrix jacchus ENSCJAG00000017450
51511 Ciona savignyi ENSCSAVG00000008099 7955 Danio rerio ENSDARG00000038868
9796 Equus caballus ENSECAG00000021744 9365 Erinaceus europaeus ENSEEUG00000004213
7425 Nasonia vitripennis 100123905 7029 Acyrthosiphon pisum 100161671
10224 Saccoglossus kowalevskii 100303466 9601 Pongo abelii 100459532
9823 Sus scrofa 100512078 7463 Apis florea 100870890
31033 Takifugu rubripes 101068755 43179 Ictidomys tridecemlineatus 101960578
8083 Xiphophorus maculatus 102234767 9606 Homo sapiens 2020
7070 Tribolium castaneum 661645 28377 Anolis carolinensis ENSACAG00000011018
9646 Ailuropoda melanoleuca ENSAMEG00000001224 9913 Bos taurus ENSBTAG00000018917
10141 Cavia porcellus ENSCPOG00000024572 9371 Echinops telfairi ENSETEG00000004995
9595 Gorilla gorilla ENSGGOG00000022981 59463 Myotis lucifugus ENSMLUG00000004165
9669 Mustela putorius furo ENSMPUG00000009596 9258 Ornithorhynchus anatinus ENSOANG00000006149
99883 Tetraodon nigroviridis ENSTNIG00000012777 9739 Tursiops truncatus ENSTTRG00000013702
69293 Gasterosteus aculeatus ENSGACG00000003888 8049 Gadus morhua ENSGMOG00000004983
9785 Loxodonta africana ENSLAFG00000032115 9103 Meleagris gallopavo ENSMGAG00000012331
13616 Monodelphis domestica ENSMODG00000004978 9986 Oryctolagus cuniculus ENSOCUG00000002453
8090 Oryzias latipes ENSORLG00000010437 7757 Petromyzon marinus ENSPMAG00000010362
13735 Pelodiscus sinensis ENSPSIG00000014871 132908 Pteropus vampyrus ENSPVAG00000003106
59729 Taeniopygia guttata ENSTGUG00000000695

Paralogs
ENSFCAG00000025025