Basic Information
Gene ID ENSOCUG00000011676
Gene Name NR3C1
Full Name Glucocorticoid receptor
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1T1R4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000010039 Gene3D G3DSA:1.10.565.10 IPR008946 532 759 1.80e-67 Nuclear hormone receptor, ligand-binding
ENSOCUP00000010039 Gene3D G3DSA:3.30.50.10 IPR013088 413 494 7.50e-27 Zinc finger, NHR/GATA-type
ENSOCUP00000010039 Pfam PF00104 IPR000536 540 729 1.00e-32 Nuclear hormone receptor, ligand-binding, core
ENSOCUP00000010039 Pfam PF00105 IPR001628 415 483 4.80e-27 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 Pfam PF02155 IPR001409 28 397 1.70e-159 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00047 IPR001628 416 432 8.50e-14 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 PRINTS PR00047 IPR001628 432 447 8.50e-14 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 PRINTS PR00047 IPR001628 466 474 8.50e-14 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 PRINTS PR00047 IPR001628 474 482 8.50e-14 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 PRINTS PR00398 IPR001723 478 488 7.70e-13 Steroid hormone receptor
ENSOCUP00000010039 PRINTS PR00398 IPR001723 562 583 7.70e-13 Steroid hormone receptor
ENSOCUP00000010039 PRINTS PR00398 IPR001723 583 599 7.70e-13 Steroid hormone receptor
ENSOCUP00000010039 PRINTS PR00398 IPR001723 652 667 7.70e-13 Steroid hormone receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 111 131 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 275 296 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 28 48 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 322 340 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 378 397 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 PRINTS PR00528 IPR001409 78 98 6.80e-71 Glucocorticoid receptor
ENSOCUP00000010039 ProSitePatterns PS00031 IPR001628 416 442 - Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 ProSiteProfiles PS51030 IPR001628 413 489 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 SMART SM00399 IPR001628 413 485 2.80e-37 Zinc finger, nuclear hormone receptor-type
ENSOCUP00000010039 SMART SM00430 IPR000536 561 725 3.50e-36 Nuclear hormone receptor, ligand-binding, core
ENSOCUP00000010039 SUPERFAMILY SSF48508 IPR008946 526 772 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000010039 PF02155 0 GCR Glucocorticoid receptor
ENSOCUP00000010039 PF00104 6.8e-33 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSOCUP00000010039 PF00105 2.7e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000010039 GO:0006351 biological_process transcription, DNA-templated
ENSOCUP00000010039 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSOCUP00000010039 GO:0016568 biological_process chromatin modification
ENSOCUP00000010039 GO:0042921 biological_process glucocorticoid receptor signaling pathway
ENSOCUP00000010039 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSOCUP00000010039 GO:0043402 biological_process glucocorticoid mediated signaling pathway
ENSOCUP00000010039 GO:0005634 cellular_component nucleus
ENSOCUP00000010039 GO:0005737 cellular_component cytoplasm
ENSOCUP00000010039 GO:0005739 cellular_component mitochondrion
ENSOCUP00000010039 GO:0003677 molecular_function DNA binding
ENSOCUP00000010039 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOCUP00000010039 GO:0003707 molecular_function steroid hormone receptor activity
ENSOCUP00000010039 GO:0004883 molecular_function glucocorticoid receptor activity
ENSOCUP00000010039 GO:0005496 molecular_function steroid binding
ENSOCUP00000010039 GO:0008270 molecular_function zinc ion binding
ENSOCUP00000010039 GO:0008289 molecular_function lipid binding
ENSOCUP00000010039 GO:0043565 molecular_function sequence-specific DNA binding
ENSOCUP00000010039 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9601 Pongo abelii 100189725 8128 Oreochromis niloticus 100534398
9597 Pan paniscus 100970978 9555 Papio anubis 101011541
39432 Saimiri boliviensis 101043581 43179 Ictidomys tridecemlineatus 101954529
59463 Myotis lucifugus 102429264 13735 Pelodiscus sinensis 102454070
9646 Ailuropoda melanoleuca ENSAMEG00000010159 9361 Dasypus novemcinctus ENSDNOG00000010685
10020 Dipodomys ordii ENSDORG00000010001 69293 Gasterosteus aculeatus ENSGACG00000018209
9031 Gallus gallus ENSGALG00000007394 9595 Gorilla gorilla ENSGGOG00000004334
9315 Macropus eugenii ENSMEUG00000009869 30608 Microcebus murinus ENSMICG00000009473
59729 Taeniopygia guttata 100008583 9796 Equus caballus 100061217
9483 Callithrix jacchus 100394916 61853 Nomascus leucogenys 100605325
9785 Loxodonta africana 100664515 10029 Cricetulus griseus 100763961
31033 Takifugu rubripes 101062852 9669 Mustela putorius furo 101688907
7897 Latimeria chalumnae 102354325 10090 Mus musculus 14815
9606 Homo sapiens 2908 9823 Sus scrofa 396740
9615 Canis familiaris 478047 9358 Choloepus hoffmanni ENSCHOG00000013777
9365 Erinaceus europaeus ENSEEUG00000008977 9371 Echinops telfairi ENSETEG00000014280
9685 Felis catus ENSFCAG00000026823 8049 Gadus morhua ENSGMOG00000005668
9103 Meleagris gallopavo ENSMGAG00000009322 9544 Macaca mulatta ENSMMUG00000000421
9258 Ornithorhynchus anatinus ENSOANG00000005745 9978 Ochotona princeps ENSOPRG00000015535
9598 Pan troglodytes ENSPTRG00000017363 132908 Pteropus vampyrus ENSPVAG00000014255
10116 Rattus norvegicus ENSRNOG00000014096 9305 Sarcophilus harrisii ENSSHAG00000001727
37347 Tupaia belangeri ENSTBEG00000016278 99883 Tetraodon nigroviridis ENSTNIG00000008946
9739 Tursiops truncatus ENSTTRG00000003260 30538 Vicugna pacos ENSVPAG00000006590
8364 Xenopus tropicalis ENSXETG00000001879 8083 Xiphophorus maculatus ENSXMAG00000009167
30611 Otolemur garnettii ENSOGAG00000003356 8090 Oryzias latipes ENSORLG00000006022
42254 Sorex araneus ENSSARG00000000617 9478 Tarsius syrichta ENSTSYG00000013696