Basic Information
Gene ID ENSPPYG00000013027
Gene Name STAT1
Full Name Signal transducer and activator of transcription
Organism Pongo abelii [9601]

Cross Reference
UniProt H2P855 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000014555 Gene3D G3DSA:1.10.238.10 IPR011992 477 597 6.00e-51 EF-hand domain pair
ENSPPYP00000014555 Gene3D G3DSA:1.10.532.10 IPR013799 17 137 7.80e-47 STAT transcription factor, protein interaction
ENSPPYP00000014555 Gene3D G3DSA:1.20.1050.20 IPR013800 153 333 1.10e-68 STAT transcription factor, all-alpha
ENSPPYP00000014555 Gene3D G3DSA:2.60.40.630 IPR012345 334 476 7.60e-66 STAT transcription factor, DNA-binding, subdomain
ENSPPYP00000014555 Gene3D G3DSA:3.30.505.10 IPR000980 598 727 6.00e-53 SH2 domain
ENSPPYP00000014555 PANTHER PTHR11801 IPR001217 18 766 0.00e-00 Transcription factor STAT
ENSPPYP00000014555 Pfam PF00017 IPR000980 594 654 7.00e-09 SH2 domain
ENSPPYP00000014555 Pfam PF01017 IPR013800 153 331 1.10e-64 STAT transcription factor, all-alpha
ENSPPYP00000014555 Pfam PF02864 IPR013801 333 583 4.60e-120 STAT transcription factor, DNA-binding
ENSPPYP00000014555 Pfam PF02865 IPR013799 18 137 3.50e-43 STAT transcription factor, protein interaction
ENSPPYP00000014555 Pfam PF12162 IPR022752 731 755 4.30e-12 Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal
ENSPPYP00000014555 ProSiteProfiles PS50001 IPR000980 589 686 0.00e-00 SH2 domain
ENSPPYP00000014555 SMART SM00252 IPR000980 591 703 1.10e-03 SH2 domain
ENSPPYP00000014555 SMART SM00964 IPR013799 18 138 1.20e-66 STAT transcription factor, protein interaction
ENSPPYP00000014555 SUPERFAMILY SSF47655 IPR015988 150 333 0.00e-00 STAT transcription factor, coiled coil
ENSPPYP00000014555 SUPERFAMILY SSF48092 IPR013799 17 137 0.00e-00 STAT transcription factor, protein interaction
ENSPPYP00000014555 SUPERFAMILY SSF49417 IPR008967 333 584 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000014555 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSPPYP00000014555 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSPPYP00000014555 PF02865 3.50325e-43 STAT_int STAT protein, protein interaction domain
ENSPPYP00000014555 PF12162 1.7e-12 STAT1_TAZ2bind STAT1 TAZ2 binding domain
ENSPPYP00000014555 PF00017 9.3e-10 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000014555 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSPPYP00000014555 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPPYP00000014555 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSPPYP00000014555 GO:0005634 cellular_component nucleus
ENSPPYP00000014555 GO:0005737 cellular_component cytoplasm
ENSPPYP00000014555 GO:0003677 molecular_function DNA binding
ENSPPYP00000014555 GO:0004871 molecular_function signal transducer activity
ENSPPYP00000014555 GO:0005509 molecular_function calcium ion binding
ENSPPYP00000014555 GO:0019901 molecular_function protein kinase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100696359 10029 Cricetulus griseus 100755609
9597 Pan paniscus 100971620 9555 Papio anubis 101005886
39432 Saimiri boliviensis 101030811 7897 Latimeria chalumnae 102353760
13735 Pelodiscus sinensis 102462741 10116 Rattus norvegicus 25124
9913 Bos taurus 510814 9544 Macaca mulatta 693650
28377 Anolis carolinensis ENSACAG00000005909 9646 Ailuropoda melanoleuca ENSAMEG00000014048
9358 Choloepus hoffmanni ENSCHOG00000013865 10141 Cavia porcellus ENSCPOG00000012673
7955 Danio rerio ENSDARG00000006266 9361 Dasypus novemcinctus ENSDNOG00000007325
10020 Dipodomys ordii ENSDORG00000011139 9796 Equus caballus ENSECAG00000009039
9365 Erinaceus europaeus ENSEEUG00000002197 9371 Echinops telfairi ENSETEG00000017040
9685 Felis catus ENSFCAG00000013725 69293 Gasterosteus aculeatus ENSGACG00000015589
9595 Gorilla gorilla ENSGGOG00000000611 9785 Loxodonta africana ENSLAFG00000001475
9315 Macropus eugenii ENSMEUG00000012165 30608 Microcebus murinus ENSMICG00000002941
59463 Myotis lucifugus ENSMLUG00000010083 13616 Monodelphis domestica ENSMODG00000011747
61853 Nomascus leucogenys ENSNLEG00000006694 9986 Oryctolagus cuniculus ENSOCUG00000002455
30611 Otolemur garnettii ENSOGAG00000003038 9978 Ochotona princeps ENSOPRG00000008589
8090 Oryzias latipes ENSORLG00000000162 9813 Procavia capensis ENSPCAG00000005867
7757 Petromyzon marinus ENSPMAG00000002770 9031 Gallus gallus ENSGALG00000007651
8049 Gadus morhua ENSGMOG00000012431 9103 Meleagris gallopavo ENSMGAG00000006382
9669 Mustela putorius furo ENSMPUG00000012530 9258 Ornithorhynchus anatinus ENSOANG00000022638
9598 Pan troglodytes ENSPTRG00000012749 132908 Pteropus vampyrus ENSPVAG00000004735
9305 Sarcophilus harrisii ENSSHAG00000016913 9823 Sus scrofa ENSSSCG00000016057
43179 Ictidomys tridecemlineatus ENSSTOG00000008620 37347 Tupaia belangeri ENSTBEG00000017412
59729 Taeniopygia guttata ENSTGUG00000010768 99883 Tetraodon nigroviridis ENSTNIG00000017161
31033 Takifugu rubripes ENSTRUG00000000102 9478 Tarsius syrichta ENSTSYG00000007651
9739 Tursiops truncatus ENSTTRG00000001134 30538 Vicugna pacos ENSVPAG00000011543
8364 Xenopus tropicalis ENSXETG00000004649 8083 Xiphophorus maculatus ENSXMAG00000001594