Basic Information | |||
Gene ID | ENSRNOG00000049232 ; ![]() ![]() | ||
Gene Name | Tcf7l2 | ||
Full Name | Protein Tcf7l2 | ||
Organism | Rattus norvegicus [10116] |
Cross Reference | |||
UniProt | D4A8X6 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSRNOP00000019681 | Gene3D | G3DSA:1.10.30.10 | IPR009071 | 158 | 240 | 5.00e-29 | High mobility group box domain |
ENSRNOP00000019681 | PANTHER | PTHR10373 | IPR024940 | 1 | 414 | 0.00e-00 | Transcription factor TCF/LEF |
ENSRNOP00000019681 | PANTHER | PTHR10373:SF26 | IPR028773 | 1 | 414 | 0.00e-00 | Transcription factor 7-like 2 |
ENSRNOP00000019681 | Pfam | PF00505 | IPR009071 | 160 | 227 | 6.40e-22 | High mobility group box domain |
ENSRNOP00000019681 | Pfam | PF08347 | IPR013558 | 1 | 75 | 2.90e-34 | CTNNB1 binding, N-teminal |
ENSRNOP00000019681 | ProSiteProfiles | PS50118 | IPR009071 | 160 | 228 | 0.00e-00 | High mobility group box domain |
ENSRNOP00000019681 | SMART | SM00398 | IPR009071 | 159 | 229 | 3.90e-25 | High mobility group box domain |
ENSRNOP00000019681 | SUPERFAMILY | SSF47095 | IPR009071 | 159 | 240 | 0.00e-00 | High mobility group box domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSRNOP00000019681 | PF08347 | 2.9e-34 | CTNNB1_binding | N-terminal CTNNB1 binding |
ENSRNOP00000019681 | PF00505 | 3.7e-22 | HMG_box | HMG (high mobility group) box |
ENSRNOP00000019681 | PF09011 | 6.6e-08 | HMG_box_2 | HMG-box domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSRNOP00000019681 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSRNOP00000019681 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSRNOP00000019681 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSRNOP00000019681 | GO:0007275 | biological_process | multicellular organismal development |
ENSRNOP00000019681 | GO:0016055 | biological_process | Wnt signaling pathway |
ENSRNOP00000019681 | GO:0060070 | biological_process | canonical Wnt signaling pathway |
ENSRNOP00000019681 | GO:0005634 | cellular_component | nucleus |
ENSRNOP00000019681 | GO:0003677 | molecular_function | DNA binding |
ENSRNOP00000019681 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSRNOP00000019681 | GO:0008013 | molecular_function | beta-catenin binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7425 | Nasonia vitripennis | 100120687 | 400682 | Amphimedon queenslandica | 100641322 |
9597 | Pan paniscus | 100978424 | 9555 | Papio anubis | 101026705 |
6239 | Caenorhabditis elegans | 171849 | 10090 | Mus musculus | 21416 |
7668 | Strongylocentrotus purpuratus | 373203 | 7227 | Drosophila melanogaster | 43769 |
7070 | Tribolium castaneum | 641465 | 9606 | Homo sapiens | 6934 |
28377 | Anolis carolinensis | ENSACAG00000010433 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000015382 |
9913 | Bos taurus | ENSBTAG00000021574 | 7719 | Ciona intestinalis | ENSCING00000002003 |
9483 | Callithrix jacchus | ENSCJAG00000018987 | 7955 | Danio rerio | ENSDARG00000004415 |
9361 | Dasypus novemcinctus | ENSDNOG00000012035 | 9796 | Equus caballus | ENSECAG00000024121 |
9371 | Echinops telfairi | ENSETEG00000018612 | 9685 | Felis catus | ENSFCAG00000018774 |
69293 | Gasterosteus aculeatus | ENSGACG00000011184 | 9031 | Gallus gallus | ENSGALG00000026476 |
9785 | Loxodonta africana | ENSLAFG00000018192 | 9315 | Macropus eugenii | ENSMEUG00000011191 |
30608 | Microcebus murinus | ENSMICG00000007510 | 9544 | Macaca mulatta | ENSMMUG00000022799 |
13616 | Monodelphis domestica | ENSMODG00000010133 | 9258 | Ornithorhynchus anatinus | ENSOANG00000001579 |
8128 | Oreochromis niloticus | ENSONIG00000016240 | 9978 | Ochotona princeps | ENSOPRG00000005139 |
8090 | Oryzias latipes | ENSORLG00000008387 | 9601 | Pongo abelii | ENSPPYG00000002661 |
9598 | Pan troglodytes | ENSPTRG00000002949 | 132908 | Pteropus vampyrus | ENSPVAG00000016688 |
7029 | Acyrthosiphon pisum | 100161896 | 6087 | Hydra magnipapillata | 100199257 |
10224 | Saccoglossus kowalevskii | 100303556 | 34638 | Metaseiulus occidentalis | 100905988 |
39432 | Saimiri boliviensis | 101037011 | 13735 | Pelodiscus sinensis | 102459521 |
9615 | Canis familiaris | ENSCAFG00000011005 | 10141 | Cavia porcellus | ENSCPOG00000002152 |
51511 | Ciona savignyi | ENSCSAVG00000007833 | 10020 | Dipodomys ordii | ENSDORG00000011398 |
9365 | Erinaceus europaeus | ENSEEUG00000007595 | 9595 | Gorilla gorilla | ENSGGOG00000008549 |
8049 | Gadus morhua | ENSGMOG00000007406 | 7897 | Latimeria chalumnae | ENSLACG00000015707 |
59463 | Myotis lucifugus | ENSMLUG00000008783 | 9669 | Mustela putorius furo | ENSMPUG00000002032 |
61853 | Nomascus leucogenys | ENSNLEG00000015863 | 9986 | Oryctolagus cuniculus | ENSOCUG00000008142 |
30611 | Otolemur garnettii | ENSOGAG00000014475 | 7757 | Petromyzon marinus | ENSPMAG00000004519 |
9305 | Sarcophilus harrisii | ENSSHAG00000017344 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000006847 |
9823 | Sus scrofa | ENSSSCG00000010638 | 37347 | Tupaia belangeri | ENSTBEG00000002995 |
59729 | Taeniopygia guttata | ENSTGUG00000010805 | 99883 | Tetraodon nigroviridis | ENSTNIG00000010305 |
31033 | Takifugu rubripes | ENSTRUG00000012549 | 9478 | Tarsius syrichta | ENSTSYG00000012796 |
9739 | Tursiops truncatus | ENSTTRG00000002360 | 30538 | Vicugna pacos | ENSVPAG00000008158 |
8364 | Xenopus tropicalis | ENSXETG00000018735 | 8083 | Xiphophorus maculatus | ENSXMAG00000014710 |
Paralogs | |||
161452 |