PredictBias

identification of genomic and pathogenicity islands in prokaryotic genome
Home | Help | Analyzed genomes
 
A) Input parameters
GenomeNCTC11044_from_ncbi.gbThreshold dinucleotide bias2
Threshold codon bias4Threshold %GC bias3
E-value (RPSBlast)0.05Genome (non-pathogenic)
 
B) Compare a potential GI or PAI in related non-pathogenic sp. (phylogenetic tree)
Potential GI or PAI start    end  
Select Organism     
 
C) Potential GIs and PAIs in NZ_LR134269 (download)
S.NoStartEndBiasVirulenceInsertion elementsPrediction
1EL082_RS00005EL082_RS00110Y        Y        YPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS000053141.913596chromosomal replication initiator protein DnaA
EL082_RS000103152.205286DNA polymerase III subunit beta
EL082_RS000152132.840347S4 domain-containing protein YaaA
EL082_RS000203142.853046DNA replication/repair protein RecF
EL082_RS000252152.914434DNA topoisomerase (ATP-hydrolyzing) subunit B
EL082_RS000302152.781489DNA gyrase subunit A
EL082_RS00035-1122.392592NAD(P)H-hydrate dehydratase
EL082_RS00040-1121.835389histidine ammonia-lyase
EL082_RS000451142.078068serine--tRNA ligase
EL082_RS000501131.632291AzlC family ABC transporter permease
EL082_RS000552162.374087AzlD domain-containing protein
EL082_RS000603182.752489alpha/beta fold hydrolase
EL082_RS000654202.983174DUF2232 domain-containing protein
EL082_RS000705203.274289DHH family phosphoesterase
EL082_RS000756192.84884250S ribosomal protein L9
EL082_RS000806203.050989replicative DNA helicase
EL082_RS000856192.515291adenylosuccinate synthase
EL082_RS001005212.548662**response regulator transcription factor
EL082_RS001053201.992242cell wall metabolism sensor histidine kinase
EL082_RS001102181.465155hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00005SECA300.019 SecA protein signature.
		>SECA#SecA protein signature.

Length = 901

Score = 30.2 bits (68), Expect = 0.019
Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 6/78 (7%)

Query: 36 QNDKAIVLVSESFNANWLNQKYSEIMQSIIYEVIGYEVEPRFITEEELSKYMNADQKQPE 95
Q D ESF+ ++ +++S+ YEVI + + EE+ + + + E
Sbjct: 796 QKDPKQEYKRESFSM------FAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAE 849

Query: 96 EPAAQETKQHQNVDNPGG 113
A + HQ+ D+
Sbjct: 850 RLAQMQQLSHQDDDSAAA 867


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00035NAFLGMOTY300.009 Sodium-type flagellar protein MotY precursor signature.
		>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature.

Length = 293

Score = 30.1 bits (67), Expect = 0.009
Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 13/92 (14%)

Query: 121 LIVDGDAITIFSKLKPQLPSCRVIFTPHQKEWERLSGIPIEEQTYERNREAVDRIGATVV 180
LI G +++ S + R + TP Q +WE + P+E Q + G V
Sbjct: 5 LITSGVMLSLLSANSYAVMGKRYVATPQQSQWEMVVNTPLECQLV----HPIPSFGDAVF 60

Query: 181 LKKHGTEIYFRNEDYKLSIGSPAMATGGMGDT 212
+ +I N D++L + P MG+T
Sbjct: 61 SSRASKKI---NLDFELKMRRP------MGET 83


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00040ANTHRAXTOXNA320.007 Anthrax toxin LF subunit signature.
		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

Length = 800

Score = 32.0 bits (72), Expect = 0.007
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 2/64 (3%)

Query: 13 EDIKQLLHQDLKIEITEEALERVKKSRSVVERIINDKETIYGITTGFGLFSDVRIDSTQY 72
E K ++ +K E T E L+++++++ ++++I D IY G F+D ID ++
Sbjct: 57 EKFKDSINNLVKTEFTNETLDKIQQTQDLLKKIPKDVLEIYSELGGEIYFTD--IDLVEH 114

Query: 73 NDLQ 76
+LQ
Sbjct: 115 KELQ 118


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00100HTHFIS936e-24 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 92.6 bits (230), Expect = 6e-24
Identities = 32/129 (24%), Positives = 67/129 (51%), Gaps = 1/129 (0%)

Query: 4 KVVVVDDEKPIADILEFNLKKEGYDVFCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGME 63
++V DD+ I +L L + GYDV + I + D+V+ D+++P + +
Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

Query: 64 VCREVRKKFE-MPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYS 122
+ ++K +P+++++A+++ + + E GA DY+ KPF ELI + L
Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

Query: 123 QPAQEVNDA 131
+P++ +D+
Sbjct: 125 RPSKLEDDS 133


2EL082_RS00295EL082_RS00610Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS002952172.083350branched-chain amino acid transport system II
EL082_RS003001192.607875acetamidase/formamidase family protein
EL082_RS003050141.401627zinc ribbon domain-containing protein
EL082_RS003150140.238130MFS transporter
EL082_RS003200131.862776hypothetical protein
EL082_RS00325-1143.370427nuclear transport factor 2 family protein
EL082_RS00335-1144.002175amidohydrolase
EL082_RS00340-1154.649445LacI family DNA-binding transcriptional
EL082_RS00345-1174.883309ribose transporter RbsU
EL082_RS003550213.764150D-ribose pyranase
EL082_RS00360-2202.707377ribokinase
EL082_RS00365-2192.883527amidohydrolase
EL082_RS00375-1171.093165DoxX family protein
EL082_RS003800170.855729DHA2 family efflux MFS transporter permease
EL082_RS00385-1140.254376arylamine N-acetyltransferase
EL082_RS003900151.226769TetR/AcrR family transcriptional regulator
EL082_RS003953162.157817ABC transporter permease
EL082_RS004003183.226913ABC transporter ATP-binding protein
EL082_RS004054213.640484TetR/AcrR family transcriptional regulator
EL082_RS004105214.512483histidine racemase CntK
EL082_RS004154224.561499staphylopine biosynthesis enzyme CntL
EL082_RS004203214.584493staphylopine biosynthesis dehydrogenase
EL082_RS004251214.594607nickel ABC transporter, nickel/metallophore
EL082_RS004305245.027035ABC transporter permease
EL082_RS004355234.701920ABC transporter permease subunit
EL082_RS004405264.080649ABC transporter ATP-binding protein
EL082_RS004453263.752962MFS transporter
EL082_RS00450-2190.532221type I toxin-antitoxin system Fst family toxin
EL082_RS00455019-1.514804type I toxin-antitoxin system Fst family toxin
EL082_RS00460018-3.303729type I toxin-antitoxin system Fst family toxin
EL082_RS00465114-1.723617VOC family protein
EL082_RS00470112-1.730190DUF2075 domain-containing protein
EL082_RS00480311-2.847992nucleotide pyrophosphohydrolase
EL082_RS00485312-2.911768PTS sugar transporter subunit IIA
EL082_RS00490414-2.017906mannose-6-phosphate isomerase, class I
EL082_RS00495419-4.788484membrane protein insertase YidC
EL082_RS00500419-4.798486stage II sporulation protein M
EL082_RS00505420-4.605455SdpI family protein
EL082_RS00510-212-2.138231hypothetical protein
EL082_RS00515-212-1.920310hypothetical protein
EL082_RS00525-1151.755564LPXTG cell wall anchor domain-containing
EL082_RS00530-2172.048089hypothetical protein
EL082_RS00535-2202.7463143-hydroxyacyl-CoA dehydrogenase
EL082_RS00540-2213.228567Crp/Fnr family transcriptional regulator
EL082_RS00545-1193.678861carbamate kinase
EL082_RS00550-1183.001317arginine-ornithine antiporter
EL082_RS005551162.749705ornithine carbamoyltransferase
EL082_RS005601162.353574arginine deiminase
EL082_RS005651152.149154ArgR family transcriptional regulator
EL082_RS005701162.454980SulP family inorganic anion transporter
EL082_RS005752141.946607accessory Sec system glycosylation chaperone
EL082_RS005801140.974662accessory Sec system glycosyltransferase GtfA
EL082_RS0058511193.292586accessory Sec system translocase SecA2
EL082_RS0059012203.513812accessory Sec system protein Asp3
EL082_RS0059511183.174634accessory Sec system protein Asp2
EL082_RS0060011193.162227accessory Sec system protein Asp1
EL082_RS0060512193.431876accessory Sec system protein translocase subunit
EL082_RS0061013214.047100KxYKxGKxW signal peptide domain-containing
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00320TCRTETB553e-10 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 54.9 bits (132), Expect = 3e-10
Identities = 52/283 (18%), Positives = 107/283 (37%), Gaps = 23/283 (8%)

Query: 77 RLGFKKNYLLFVSFFLIGSIIGLISQDLIVLSI-AKIIQSVSTGVLFFTLLPQLFRNFPR 135
+LG K+ L + GS+IG + L I A+ IQ ++ + R P+
Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134

Query: 136 RFRNVFLLFVIVGLFGANALGGLSGSVSLELDSWHWVFVLNIVSAIVCLIFGTVFLNKEE 195
R + + +G G + HW ++L I + + + L K+E
Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLLKKE 192

Query: 196 HKHVSSNSIDYVLIILLFLTILCFVIPMAMLTQKGYSSLWVWPFLLLAMFFLVNFIYRNM 255
+ D IIL+ + I+ F ML YS FL++++ + F+
Sbjct: 193 VRI--KGHFDIKGIILMSVGIVFF-----MLFTTSYS----ISFLIVSVLSFLIFVKHIR 241

Query: 256 HSSSPLVYFKTLFAKKPSV-GAVMAISSHLTLLTGIAGINVFLTKILKLPFEDIARFYVC 314
+ P V L P + G + T+ ++ + + + +L +I
Sbjct: 242 KVTDPFVDPG-LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS---- 296

Query: 315 FFIGVVIAGFIKMFFYSAIGAGILGSLGSVALLYVSVHWIAMG 357
++ G + + + IG ++ G + +L + V ++++
Sbjct: 297 ---VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS 336


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00380TCRTETB1408e-39 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 140 bits (353), Expect = 8e-39
Identities = 97/420 (23%), Positives = 188/420 (44%), Gaps = 15/420 (3%)

Query: 4 TQPSHLNIKQRNLMIAVMMIGAFIGVLNQTLLTTILPEVMKDFAISSSTAQWLTTIFMLV 63
T S N++ ++I + ++ +F VLN+ +L LP++ DF ++ W+ T FML
Sbjct: 3 TSYSQSNLRHNQILIWLCIL-SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLT 61

Query: 64 NGIMIPVTAYLIERFSLRTLFFTAATCLILGSLICMLGVN-FPLLLVGRSIQALGAGILM 122
I V L ++ ++ L GS+I +G + F LL++ R IQ GA
Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121

Query: 123 PLSQTLLFIIFPVEKRGMAMGIFGLVIGFAPAIGPTAAGWFIHLFDWRYLFLVVLLISVV 182
L ++ P E RG A G+ G ++ +GP G H W YL L + +I+++
Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLL-IPMITII 180

Query: 183 DAIFGFLYLKNITETQQPSLDILSVIMSTLGFGGLLYGFSSAGNLGCSHPSVYVTIIISI 242
F LK + DI +I+ ++G + +S +I+S+
Sbjct: 181 TVPFLMKLLKKEVRIKGH-FDIKGIILMSVGIVFFMLFTTSY---------SISFLIVSV 230

Query: 243 IILALFIRRQLKLPSPLLEFRVFKYRSFTISMTLIVLMFVLFIGNLTILPIYMQTMMHWS 302
+ +F++ K+ P ++ + K F I + ++F G ++++P M+ + S
Sbjct: 231 LSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLS 290

Query: 303 PLESG-LILLPGGLVMGLLSPVTGKLYDRVGGRSLSITGMLLIMIGALFMAQFNPQTSAL 361
E G +I+ PG + + + + G L DR G + G+ + + L + F +T++
Sbjct: 291 TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-FLLETTSW 349

Query: 362 YVIVTFSILMLGNSMIMTPMTTQALNALPVSLIAHGTAMNNTIRQISAAIGTGILVTLMT 421
++ + ++ G S T ++T ++L G ++ N +S G I+ L++
Sbjct: 350 FMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00390HTHTETR559e-12 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 55.4 bits (133), Expect = 9e-12
Identities = 29/143 (20%), Positives = 52/143 (36%), Gaps = 10/143 (6%)

Query: 10 RKKRSDATHNKAIILQTTTQLLAQGEDISEMNMSEIAKKAGVGVGTLYRHFESKSLLCQA 69
RK + +A + IL +L +Q + +S ++ EIAK AGV G +Y HF+ KS L
Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQ-QGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61

Query: 70 MMDEKVHDMFDEMDTFLHQHQDASVRDKIYGILSIYLDLKEANFN---VLNFIEKSNSQH 126
+ + E++ + IL L+ ++ I
Sbjct: 62 IWEL-SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

Query: 127 QSMINI-----LFYEQLKELIKD 144
M + + + I+
Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQ 143


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00395ABC2TRNSPORT565e-11 ABC-2 type transport system membrane protein signat...
		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

signature.
Length = 262

Score = 55.7 bits (134), Expect = 5e-11
Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 3/168 (1%)

Query: 191 RERTTGTLERVLATPIRRSEIVFGYLLGYGIFAIIQTLIIVLFSIYLLNINLAGSLWYVL 250
R T E +L T +R +IV G + A + I + + L SL Y L
Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL-SLLYAL 151

Query: 251 LINILLAITALVMGIFISTFANSEFQMVQFIPIVAIPQVFFSG-IFPLENMTPWLANIGY 309
+ L + +G+ ++ A S + + +V P +F SG +FP++ +
Sbjct: 152 PVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAAR 211

Query: 310 LFPLRYAGDALTNIMIKGQGWSDIWFDVLILLIFIIIFIILNILGLKR 357
PL ++ D + IM+ D+ V L I+I+I L+ L+R
Sbjct: 212 FLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIPFFLSTALLRR 258


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00405HTHTETR453e-08 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 45.4 bits (107), Expect = 3e-08
Identities = 13/65 (20%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 24 LLNVKSYDDISIKDICDESGISRGTFYQHYRDKDDFLFQYQKAMMKKGKRRLTQIQFEER 83
L + + S+ +I +G++RG Y H++DK D + + + + +++ E +
Sbjct: 23 LFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF----SEIWELSESNIGELELEYQ 78

Query: 84 RQFFE 88
+F
Sbjct: 79 AKFPG 83


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00425adhesinb330.002 Adhesin B signature.
		>adhesinb#Adhesin B signature.

Length = 310

Score = 32.9 bits (75), Expect = 0.002
Identities = 16/71 (22%), Positives = 28/71 (39%), Gaps = 8/71 (11%)

Query: 9 AVLLASGIILTGCGGNKGLEDKKEQKTLSYTTVKDIGDMNPHVYGGSMSAESMI------ 62
+LL + + L C K + K T I D+ ++ G ++ S++
Sbjct: 8 VLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDP 67

Query: 63 --YEPLVRNTK 71
YEPL + K
Sbjct: 68 HEYEPLPEDVK 78


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00450TCRTETA362e-04 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 36.3 bits (84), Expect = 2e-04
Identities = 50/263 (19%), Positives = 85/263 (32%), Gaps = 9/263 (3%)

Query: 8 LFLRLYILTLMFFSANAILNVFIPLRGHDLGATNT---TIGIVMGAYMLTAMVFRPWAGQ 64
L + L + L I+ V +P DL +N GI++ Y L P G
Sbjct: 7 LIVILSTVALDAVGIGLIMPV-LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65

Query: 65 IIARVGPIKVLRIILLINACALILYGLTG-LEGYFIARVMQGVCTAFFSMSLQLGIIDAL 123
+ R G VL + L A + L +I R++ G+ A +++ I D
Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAY-IADIT 124

Query: 124 PEEHRSEGVSLYSLFSTIPNLVGPLIA--VGIWHLDRISIFAIVMIAIALTTTFFGYRVT 181
+ R+ S + GP++ +G + A + + T F +
Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184

Query: 182 FASEEPDTRKKVEPLPFNAVTVFAQFFKNKELFNSGLIMIVVSIVFGAVSTFVPLYTVKF 241
E ++ P + L IM +V V A+ +
Sbjct: 185 HKGER-RPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHW 243

Query: 242 GFADAGIFLTIQAIAVVLARIYL 264
GI L I LA+ +
Sbjct: 244 DATTIGISLAAFGILHSLAQAMI 266


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00490TCRTETA310.011 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 31.3 bits (71), Expect = 0.011
Identities = 19/93 (20%), Positives = 33/93 (35%), Gaps = 16/93 (17%)

Query: 401 RIIP--SNMIGAMVAAVIAAMGGVGDRVAH-------------GGPIVA-VLGGIDHIIW 444
RI+ + GA+ A IA + +R H GP++ ++GG
Sbjct: 103 RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP 162

Query: 445 FFIAVIIGSLVTMITILILKRNTPVTDVEEDQE 477
FF A + L + +L + +E
Sbjct: 163 FFAAAALNGLNFLTGCFLLPESHKGERRPLRRE 195


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS0050060KDINNERMP1288e-36 60kDa inner membrane protein signature.
		>60KDINNERMP#60kDa inner membrane protein signature.

Length = 548

Score = 128 bits (322), Expect = 8e-36
Identities = 70/243 (28%), Positives = 109/243 (44%), Gaps = 28/243 (11%)

Query: 29 GFFYNTFAKPMDLFLNWMGEHLNHNYGLAIIIIVLAIRLIMLPFMLSQTKNGQFMRKLMK 88
G+ + ++P+ L W+ + N+G +IIII +R IM P +Q + MR L
Sbjct: 331 GWLW-FISQPLFKLLKWIHSFVG-NWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRML-- 386

Query: 89 IAKPELDPIQEKVRRARTQEEKMDANKEMMDVYKKYHINPMKSMLGCLPMLIQMPILFGL 148
+P++ ++E++ +K ++EMM +YK +NP+ GC P+LIQMPI L
Sbjct: 387 --QPKIQAMRERLGD-----DKQRISQEMMALYKAEKVNPLG---GCFPLLIQMPIFLAL 436

Query: 149 YASLKWPVHNHLSQYPHFLWF-DLSNPDIYITL--IAGILYFIQSLVSLGNMPQEQRQMG 205
Y L V L Q P LW DLS D Y L + G+ F +S + +Q
Sbjct: 437 YYMLMGSV--ELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQ-- 492

Query: 206 YMMMVISPIFIIYISFTSASALGLYWSINALFLIIQMYFSNQYYSKIADEYVKSFEKQND 265
+M P+ S L LY+ ++ L IIQ + K + +
Sbjct: 493 -KIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEK------RGLHSREK 545

Query: 266 KKS 268
KKS
Sbjct: 546 KKS 548


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00545CARBMTKINASE389e-138 Bacterial carbamate kinase signature.
		>CARBMTKINASE#Bacterial carbamate kinase signature.

Length = 314

Score = 389 bits (1000), Expect = e-138
Identities = 136/314 (43%), Positives = 196/314 (62%), Gaps = 5/314 (1%)

Query: 1 MDNKIVIALGGNALQTD--DGSADAQRKAIRSTMQALKPLFDTDADIVISHGNGPQIGTM 58
M ++VIALGGNALQ GS + +R T + + + ++VI+HGNGPQ+G++
Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60

Query: 59 LIQQAKADS-PQTPAMPLDVCGSMTQGMIGFWIETEVNRVLAEIKSPRRAGTVITRVEVD 117
L+ + PA P+DV G+M+QG IG+ I+ + L + ++ T+IT+ VD
Sbjct: 61 LLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVD 120

Query: 118 EHDPRMSNPTKPIGPFYTKEEAEQLQQANPESTYKEDAGRGYRKVVPSPLPVSILEHQLI 177
++DP NPTKP+GPFY +E A++L KED+GRG+R+VVPSP P +E + I
Sbjct: 121 KNDPAFQNPTKPVGPFYDEETAKRLA-REKGWIVKEDSGRGWRRVVPSPDPKGHVEAETI 179

Query: 178 STLVENQNIIIACGGGGIPVIKRNDTYEGVEAVIDKDFASERLAQLIDANTLMILTNVEH 237
LVE I+IA GGGG+PVI + +GVEAVIDKD A E+LA+ ++A+ MILT+V
Sbjct: 180 KKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNG 239

Query: 238 VYINYNEPNQEALTNVDVATLKQYAKDGKFAEGSMLPKIEAAIDFVESGEGRRAIITNLD 297
+ Y ++ L V V L++Y ++G F GSM PK+ AAI F+E G G RAII +L+
Sbjct: 240 AALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWG-GERAIIAHLE 298

Query: 298 NAYEAFKGHVGTQI 311
A EA +G GTQ+
Sbjct: 299 KAVEALEGKTGTQV 312


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00560ARGDEIMINASE502e-180 Bacterial arginine deiminase signature.
		>ARGDEIMINASE#Bacterial arginine deiminase signature.

Length = 409

Score = 502 bits (1293), Expect = e-180
Identities = 185/409 (45%), Positives = 272/409 (66%), Gaps = 8/409 (1%)

Query: 5 PIHVNSEIGKLKTVLLKRPGKELENLVPDHLSGLLFDDIPYLKVAQEEHDHFAQVLRDEG 64
PI++ SEIG+LK VLL RPG+ELENL P + LFDDIPYL+VA++EH+ FA +L++
Sbjct: 7 PINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNL 66

Query: 65 VEVVYLEHLAAEAIADA-SVREQFIDDILKESQKTVLGHEKEIKELFATLNDQELVEKIM 123
VE+ Y+E L +E + + ++ +FI + E++ +K+ F++L ++ K++
Sbjct: 67 VEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSLTIDNMISKMI 126

Query: 124 AGVRKEEIQLETNHLVEYMDDRYPFYLDPMPNLYFTRDPQASVGRGMTINRMYWRARRRE 183
+GV EE++ T+ L + ++ F +DPMPN+ FTRDP AS+G G+TIN+M+ + R+RE
Sbjct: 127 SGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKVRQRE 186

Query: 184 SIFMTYILKYHPRFKNDDVPVWLDRNSPFNIEGGDELILSKDVLAVGISERTSAQAIERL 243
+IF YI KYHP +K +VP+WL+R ++EGGDEL+L+K +L +GISERT A+++E+L
Sbjct: 187 TIFAEYIFKYHPVYKE-NVPIWLNRWEEASLEGGDELVLNKGLLVIGISERTEAKSVEKL 245

Query: 244 ARQILFDDQSTFTKVLAIEIPNSRTFMHLDTVFTMIDYDKFTMHAAIFKEEDNMNIFTIE 303
A LF ++++F +LA +IP +R++MHLDTVFT IDY FT + + +I+ +
Sbjct: 246 AIS-LFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSD---DMYFSIYVLT 301

Query: 304 KDEQGQDIKITHSNK-LKETLEDALNIDNIEFIPTGNGDVIDGAREQWNDGSNTLTIRPG 362
+ I I +K+ L L I+ I GD+I GAREQWNDG+N L I PG
Sbjct: 302 YNPSSSKIHIKKEKARIKDVLSFYLG-RKIDIIKCAGGDLIHGAREQWNDGANVLAIAPG 360

Query: 363 VVVTYDRNYVSNQLLRDKGIKVIEITGSELVRGRGGPRCMSQPLYREDI 411
++ Y RN+V+N+L + GIKV I SEL RGRGGPRCMS PL REDI
Sbjct: 361 EIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00565ARGREPRESSOR836e-23 Bacterial arginine repressor signature.
		>ARGREPRESSOR#Bacterial arginine repressor signature.

Length = 149

Score = 82.6 bits (204), Expect = 6e-23
Identities = 51/149 (34%), Positives = 80/149 (53%), Gaps = 2/149 (1%)

Query: 1 MRKSKRLDLISTIVKDNDIRSKAEIVDYLDKHFGIKYSVATISRDLNELKIYKMPTANND 60
M K +R I I+ N+I ++ E+VD L K G + AT+SRD+ EL + K+PT N
Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKD-GYNVTQATVSRDIKELHLVKVPTNNGS 59

Query: 61 RCYRKFNDNAQNEAKTKLIAFYNDEIEKVTIKDQYLIVKTSPGFAQSVNFYIDQLNLNEV 120
Y D N +KL D K+ +++KT PG AQ++ +D L+ E+
Sbjct: 60 YKYSLPADQRFNPL-SKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEEI 118

Query: 121 LGTVGGNDTILILVSSADVTEFVHYQLFG 149
+GT+ G+DTILI+ + D T+ V ++
Sbjct: 119 MGTICGDDTILIICRTHDDTKVVQKKILE 147


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00585SECA6590.0 SecA protein signature.
		>SECA#SecA protein signature.

Length = 901

Score = 659 bits (1702), Expect = 0.0
Identities = 273/836 (32%), Positives = 446/836 (53%), Gaps = 66/836 (7%)

Query: 10 NHMRLKKLYKILNKINRYSEDMRQYSDEQLQDKTIDFKQQLQDGNATLNDILPEAYAVVR 69
N L+++ K++N IN +M + SDE+L+ KT +F+ +L+ G L +++PEA+AVVR
Sbjct: 14 NDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGE-VLENLIPEAFAVVR 72

Query: 70 EASRRVLGMYHKDVQVLGAIVMHQGNISEMQTGEGKTLTATLPLYLNALSGKSVFLITTN 129
EAS+RV GM H DVQ+LG +V+++ I+EM+TGEGKTLTATLP YLNAL+GK V ++T N
Sbjct: 73 EASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVN 132

Query: 130 DYLAKRDYEEMKPLYEWLGLTTSLGFVENPQGPISNQEKQTLYHHDIIYTTNGNLGFDYL 189
DYLA+RD E +PL+E+LGLT G K+ Y DI Y TN GFDYL
Sbjct: 133 DYLAQRDAENNRPLFEFLGLTV--GINLPGMPA---PAKREAYAADITYGTNNEYGFDYL 187

Query: 190 IDNLADTKESKFLPELHYALIDEVDSIILDAAQTPLVISGAPRVQSNLFEIVKAFVATLK 249
DN+A + E + +LHYAL+DEVDSI++D A+TPL+ISG S +++ V + L
Sbjct: 188 RDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLI 247

Query: 250 E-----------DQDFKMKKTKREIWLTEQGIEKA-------NTYFDVSNIYDAPYFDLV 291
+ F + + R++ LTE+G+ + ++Y L+
Sbjct: 248 RQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLM 307

Query: 292 RNINLALRATYLFDLNLDYIIMDGEIMLIDRITGRMLPGTKMQAGLNQALEAKEHLDISD 351
++ ALRA LF ++DYI+ DGE++++D TGR + G + GL+QA+EAKE + I +
Sbjct: 308 HHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQN 367

Query: 352 DMSVMATITFQNLFMQFERFSGMTATGKLAEKEFFDLYSKIVIQIPTSNPVIRRDLPDKV 411
+ +A+ITFQN F +E+ +GMT T EF +Y + +PT+ P+IR+DLPD V
Sbjct: 368 ENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLV 427

Query: 412 FVNDDDKNVAILDTVIDYHQKHRPVLLITRTAEAAEYFSSELFNRHIPNNLLIAQNVARE 471
++ + +K AI++ + + K +PVL+ T + E +E S+EL I +N+L A+ A E
Sbjct: 428 YMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE 487

Query: 472 AQMIAEAGQLNAVTVATSMAGRGTDIKL-----------------------------SKE 502
A ++A+AG AVT+AT+MAGRGTDI L
Sbjct: 488 AAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDA 547

Query: 503 VHELGGLTVLINEHMENSRIDRQLRGRAGRQGDPGQSQIFISLDDYLVQRWSDSKLKDNP 562
V E GGL ++ E E+ RID QLRGR+GRQGD G S+ ++S++D L++ ++ ++
Sbjct: 548 VLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMM 607

Query: 563 SLMKQDTAYLSDSPTFNNKIKRIVKKAQRVSEEEGMKARETANEFEKSISTQRQLIYSER 622
+ + + + + AQR E R+ E++ + QR+ IYS+R
Sbjct: 608 RKLGMKP----GEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQR 663

Query: 623 NRILNSENLDDL---DFESIARDVFNHDFKTDGSMTRDHIVRYIYK-----NLSFSFVDA 674
N +L+ ++ + E + + + I + +L +
Sbjct: 664 NELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEW 723

Query: 675 NFEFNHQNHDENIEFLITQFKDQLATNKQKISDNELYQQFLRKAVLKAIDTSWIEQVDYL 734
+ + + E ++ Q + K+++ E+ + F + +L+ +D+ W E + +
Sbjct: 724 LDKEPELHEETLRERILAQSIEVYQ-RKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782

Query: 735 QQLKANVNQRQKGQRNSIFEYHKVALDSFNDMEHDIKHRMIRNLCLSIIDEQQNGD 790
L+ ++ R Q++ EY + + F M +K+ +I L + + +
Sbjct: 783 DYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVE 838


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00605SECYTRNLCASE1466e-42 Preprotein translocase SecY subunit signature.
		>SECYTRNLCASE#Preprotein translocase SecY subunit signature.

Length = 437

Score = 146 bits (371), Expect = 6e-42
Identities = 95/423 (22%), Positives = 189/423 (44%), Gaps = 37/423 (8%)

Query: 14 LYKRILFTLMIIFIYILGSNIKI--------ADMKSSAQHTNQFLDLAISNIGGDITTLN 65
L K++LFTL II +Y +G++I I A L GG + +
Sbjct: 14 LRKKLLFTLAIIVVYRVGTHIPIPGVDYKNVQQCVREASGNQGLFGLVNMFSGGALLQIT 73

Query: 66 LFSLGLSPWLTTMIIMTLLT--YRNMEKGQKQTRLERSYKE---RFFTILLALIQGYFIL 120
+F+LG+ P++T II+ LLT +E +K+ + + R+ T+ LA++QG ++
Sbjct: 74 IFALGIMPYITASIILQLLTVVIPRLEALKKEGQAGTAKITQYTRYLTVALAILQGTGLV 133

Query: 121 SEYINKGMIHHANFP-------------LMLLILVAGTMLLVWLADQNTVYGIAGPTPIV 167
+ + + + M++ + AGT +++WL + T GI I+
Sbjct: 134 ATARSAPLFGRCSVGGQIVPDQSIFTTITMVICMTAGTCVVMWLGELITDRGIGNGMSIL 193

Query: 168 LVSIIKSMFQNKHLQLLDTQTMMIGGI-------MILVVLILLLFIEMIEYR--MIY--R 216
+ I + F + + T+ G I + L+++ L++F+E + R + Y R
Sbjct: 194 MFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGLIMVALVVFVEQAQRRIPVQYAKR 253

Query: 217 DIMNISTSKKDTYVSWKLNPAGSISIMFNFSLFFLLGVLIHLVGRWITGDAQYRPPFLEL 276
I S TY+ K+N AG I ++F SL ++ ++ G + +
Sbjct: 254 MIGRRSYGGTSTYIPLKVNQAGVIPVIFASSLLYIPALVAQFAGGNSGWKSWVEQNLTKG 313

Query: 277 DNPIGVLIFIIMLIILNYYLSRVMLNTKRIAKDFQKSGNYFDGIYPGDDTRHYLDRRAKK 336
D+PI ++ + ++++ ++ + N + +A + +K G + GI G T YL +
Sbjct: 314 DHPIYIVTYFLLIVFFAFFYVAISFNPEEVADNMKKYGGFIPGIRAGRPTAEYLSYVLNR 373

Query: 337 ISAIGALIIGFIISLPFISSIFISGIYDQISIFTQFIILIYITINITETIRTYLYFDKYK 396
I+ G+L +G I +P ++ + + T +I++ + + + I + L Y+
Sbjct: 374 ITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILIIVGVGLETVKQIESQLQQRNYE 433

Query: 397 SFL 399
FL
Sbjct: 434 GFL 436


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00610ICENUCLEATIN731e-14 Ice nucleation protein signature.
		>ICENUCLEATIN#Ice nucleation protein signature.

Length = 1258

Score = 73.3 bits (179), Expect = 1e-14
Identities = 272/1086 (25%), Positives = 469/1086 (43%), Gaps = 6/1086 (0%)

Query: 1167 TSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSMSSSLSDSSSTSDSTSTSLS 1226
T S + + + + + S + D +T +S ST +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 1227 DSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSNSQSTSTSTS 1286
+ + S S + ST T+ +ST ++ ST + + S + ST
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1287 LSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDS 1346
+G ES+ + S + S T+ S+ T+G S + ST T+ DS+ T+
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1347 TSGSTSTSLSDSSSTSGSTSLSDSQST------STSTSLSDSTSTSDSTSTSLSDSSSTS 1400
S T+ SD ++ GST + + S+ ST T+ +ST T+ ST + S
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1401 GSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSES 1460
+ S + S+ ++G ST T+ S ++ ST T+ S T+G S + +
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 1461 TSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTS 1520
S+ + ST T+ S T+ S ++ GS + ST T+ S + ST
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 1521 TSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTS 1580
T+ DSS T+G S +Q S T+ GS ST+ S + S T+ S ++
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 1581 GSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSDS 1640
GST + + S + S ST+ ++S+ + S+ T+ S+ + ST T+ SD
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 1641 TSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSES 1700
T+ S ++ S S+ ++ ST T++ S T+ ST T+ S T G S S + +
Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636

Query: 1701 TSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTS 1760
S+ + ST T+ S T+ S ++ GS +G STST+ + S+ + ST
Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696

Query: 1761 TSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTS 1820
T+ +S T+G S ++ S TS STST+ + S+ ++ ST ++ S +
Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756

Query: 1821 TSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSES 1880
ST + +S T+ S S++ +DS+ + S+ T+G S+ + ST T+ S+
Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816

Query: 1881 TSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLS 1940
T+ S S + + S + S ++ S + ST T+ SD T+ STST+
Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876

Query: 1941 DSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTS 2000
DSS +G S + S T+ ST T+ S + STS + S + ST
Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQ 936

Query: 2001 LSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTS 2060
+ ST + S + S T+ GS S + S + S T+ S ++
Sbjct: 937 TASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGY 996

Query: 2061 GSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTS 2120
GST ++ ST T+ S++T+ +DS+ + SS TSG S + ST S S
Sbjct: 997 GSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVL 1056

Query: 2121 TSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGSTSMI 2180
T+ S+ +S S+ + S+ ++ SS ++ ST + + S+ + S T+
Sbjct: 1057 TAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGY 1116

Query: 2181 SSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTS 2240
S S + S + + +DS+ T+G S + + S T+ S T+ +
Sbjct: 1117 RSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCIL 1176

Query: 2241 LSDSSS 2246
++ S
Sbjct: 1177 MAGDRS 1182



Score = 72.5 bits (177), Expect = 2e-14
Identities = 267/1079 (24%), Positives = 467/1079 (43%)

Query: 1217 TSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLS 1276
T S + + + + + S + T D++ SGST +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 1277 NSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTS 1336
+ +T S S + S+ T+ +ST ++ ST + + S + ST
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1337 LSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDS 1396
+ S+ + GST T + S T+G S + S+ + ST T+ S+ +
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1397 SSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLS 1456
ST + SD + ST +G++S+ + S ++ +ST T+ S+ T+ S
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1457 DSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTS 1516
+ ST T+ DS+ + S T+ S ++ GST + S T+ S T+ +
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 1517 DSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDS 1576
DS+ + S+ T+G S + ST T+ GS+ T+ S + S + S
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 1577 SSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSES 1636
++ S+ + ST T+ SD T+ STST+ +SS +G S + ST T+
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 1637 SSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLS 1696
S T+ + SD + GSTS + + S+ + S T++ +S T+ S+ T S
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 1697 DSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTS 1756
+ S T+ SDS+ + S T++ S ++ GST + +S T+ S ST+ +
Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636

Query: 1757 DSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDS 1816
DS+ + S+ T+G S+ + ST T+ S T+ STS + + S+ + S
Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696

Query: 1817 ESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLS 1876
+ S +G ST T+ SD +S STST+ +DSS +G S + S+ T+
Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756

Query: 1877 GSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTS 1936
GS T+ S+ + S ST+ + S + GST + S T+ S T+ S
Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816

Query: 1937 TSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTS 1996
T+ S+ST+G+ S + ST T+ +S T+ ST + +S + S S +
Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876

Query: 1997 TSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDS 2056
S+ ++ ST + S+ + S T+ S+ T+ S S + S + S
Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQ 936

Query: 2057 SSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLS 2116
+++ ST ++ S+ T+ +SS T+ STS + DSS +G S + ST T+
Sbjct: 937 TASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGY 996

Query: 2117 DSTSTSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGS 2176
ST T++ +ST + ST+ + + SS + SS S S + S S S
Sbjct: 997 GSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVL 1056

Query: 2177 TSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNS 2236
T+ S S S T+ S + SS +G S + + S + S+ T+
Sbjct: 1057 TAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGY 1116

Query: 2237 TSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSDSV 2295
ST +S + S+ + ++ + ST + S + + S + S T+ +D +
Sbjct: 1117 RSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCI 1175



Score = 70.9 bits (173), Expect = 5e-14
Identities = 261/1047 (24%), Positives = 461/1047 (44%), Gaps = 2/1047 (0%)

Query: 1354 SLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTST 1413
+ ++ + GS ++ + + S S + + +T S T
Sbjct: 114 ACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQ 173

Query: 1414 STSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTST 1473
S ++G ST T+ S + ST T+ +DS+ +G S + S+ + ST T
Sbjct: 174 SQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQT 233

Query: 1474 SDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGST 1533
S T+ S ++ S+ ++ ST T+ S T+ ST T+ S T+G
Sbjct: 234 GMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYG 293

Query: 1534 SLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTST 1593
S + + S+ + GS T+ S + S T+ SD ++ GST + S+
Sbjct: 294 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 353

Query: 1594 STSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSDSTSTSLSDSSSMSG 1653
+ S T+ DS+ T+ S+ T+ S + ST T+ + S + S ++
Sbjct: 354 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEE 413

Query: 1654 STSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSESTSASTSLSDSTST 1713
ST + ST T+ SD T+ ST T+ DSS G S + S+ T+ ST T
Sbjct: 414 STQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQT 473

Query: 1714 STSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSGST 1773
+ SD T+ S S++ S+ ++G ST T+ S T+ ST T+ ++S +G
Sbjct: 474 AQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYG 533

Query: 1774 SLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTST 1833
S S + + S+ + ST T+ S + ST + SD + ST +GS+S+
Sbjct: 534 STSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSII 593

Query: 1834 SSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTST 1893
+ S +++ S+ T+ S+ T+ S+ + STST+ + S + S +
Sbjct: 594 AGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYN 653

Query: 1894 SDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSD 1953
S T+ S ++ GS + STST+ + S + ST T+ +S T+G S
Sbjct: 654 SILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQT 713

Query: 1954 SESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTST 2013
++ S TS STST+ + S+ ++ ST ++ S + ST + S +
Sbjct: 714 AQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYG 773

Query: 2014 SLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTST 2073
S S + + S + GS T+ S+ + S T+ SD ++ GSTS + ++S+
Sbjct: 774 STSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLI 833

Query: 2074 STSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSS 2133
+ S+ T+ +S T+ S+ T+ S + STST+ DS+ + ST + +
Sbjct: 834 AGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYN 893

Query: 2134 STSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGSTSMISSESTSTSTSGST 2193
S + S+ + S + STS T+ S + GST S +ST + GS+
Sbjct: 894 SILTAGYGSTQTAQENSDLTTGYGSTS--TAGYESSLIAGYGSTQTASFKSTLMAGYGSS 951

Query: 2194 STSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSSSMSGSTSL 2253
T+ S+ + STS + S + ST + ST + S + S T+
Sbjct: 952 QTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAG 1011

Query: 2254 SGSVSTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSDSVSTSTSTSESSSISTSDST 2313
GS +T+ + S + S TS S ++ GST +S S T+ SS IS S+
Sbjct: 1012 YGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLISGRRSS 1071

Query: 2314 STSTSESSSTSTSNSTSTSLSDSSSTSGSTSLSDSVSTSTSSSLSDSTSLSGSVSTSTST 2373
T+ S+ ++ S+ + +S+ +G+ S+ + S+ ++ ST +SG+ S +
Sbjct: 1072 LTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAG 1131

Query: 2374 SESSSISTSDSTSTSTSDSASMSTSDS 2400
I+ +DST T+ S ++ ++S
Sbjct: 1132 ERGKLIAGADSTQTAGDRSKLLAGNNS 1158



Score = 70.9 bits (173), Expect = 6e-14
Identities = 263/1092 (24%), Positives = 462/1092 (42%)

Query: 1263 LSDSSSTSGSTSLSNSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGS 1322
+ +S + + + +G S +S + + + T + S S
Sbjct: 95 VGTKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQ 154

Query: 1323 TSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDS 1382
+ + +T ST S + GST T+ S+ +G S + + ST + S
Sbjct: 155 PTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGS 214

Query: 1383 TSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTS 1442
T T+ S+ ++ ST SD + ST +G +S+ + S ++ DS+ T+
Sbjct: 215 TQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTA 274

Query: 1443 LSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQS 1502
S+ T+ S + ST T+ +DS+ + S T+ S ++ GST + S
Sbjct: 275 GYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGS 334

Query: 1503 TSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDS 1562
T+ S T+ DS+ + S+ T+G S + ST T+ GS+ T+ S +
Sbjct: 335 DLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTA 394

Query: 1563 SSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTS 1622
+ S + S ++ ST + ST T+ SD T+ ST T+ DSS +G S
Sbjct: 395 GADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGS 454

Query: 1623 LSDSESTSTSTSESSSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTS 1682
+ S+ T+ S T+ SD ++ GSTS + ES+ + S T+ ST T+
Sbjct: 455 TQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTA 514

Query: 1683 LSDSSSTNGSTSLSDSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSES 1742
S+ T + S + S ST+ ++S+ + S T++ S ++ GST + S
Sbjct: 515 GYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGS 574

Query: 1743 TSTSTSLSNSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLS 1802
T+ S T+ SDS+ + S+ T+ S + ST T+ S T+ STS +
Sbjct: 575 DLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTA 634

Query: 1803 DSSSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTS 1862
+ S+ + S + S +G ST T+ SD ++ STST+ +DSS +G S
Sbjct: 635 GADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGS 694

Query: 1863 LSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTS 1922
+ S T+ GS T+ S S S ST+ + S + GST + S+ T+
Sbjct: 695 TQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTA 754

Query: 1923 TSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSS 1982
S T+ S T+ S+ST+G+ S + ST T+ S T+ ST + S
Sbjct: 755 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERS 814

Query: 1983 TSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDS 2042
+ S S + + S+ ++ ST + S+ + S T+ S+ T+ S S +
Sbjct: 815 DLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTA 874

Query: 2043 TSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTS 2102
S + S ++ S + ST T+ S T+ STST+ +SS +G S
Sbjct: 875 GYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGS 934

Query: 2103 LSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGS 2162
+ ST + S+ T+ S+ + STS + SS + S+ + ST +
Sbjct: 935 TQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTA 994

Query: 2163 TSTSLSDSSSTSGSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTS 2222
S + +S T+ S +T+ + S + S+ TS S T+G S S S
Sbjct: 995 GYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRS 1054

Query: 2223 ASTSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDS 2282
T+ S+ S S+ + S ++ S ++ ST ++ + S + S +
Sbjct: 1055 VLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTA 1114

Query: 2283 SSMSGSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGS 2342
S S +DSV + + + + S T+ S+ + + S T+ S ++ +
Sbjct: 1115 GYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDC 1174

Query: 2343 TSLSDSVSTSTS 2354
++ S T+
Sbjct: 1175 ILMAGDRSKLTA 1186



Score = 70.9 bits (173), Expect = 6e-14
Identities = 267/1069 (24%), Positives = 469/1069 (43%), Gaps = 6/1069 (0%)

Query: 1072 SESTSTSTSLSDSTSTSDSTSTSLSNSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTST 1131
+E T S + ++ + +G S + T D+T
Sbjct: 90 AEVLHVGTKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIE 149

Query: 1132 SLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQ 1191
S S + + + S + T S + S T+G +ST ++ ST + + S
Sbjct: 150 SGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLV 209

Query: 1192 STSTSTSLSGSESTSMSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSD 1251
+ ST +G ES+ M+ S + S T+ S+ T+G S + ST T+ D
Sbjct: 210 AGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGED 269

Query: 1252 STSTSDSTSTSLSDSSSTSGSTSLSNSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTST 1311
S+ T+ ST + S + S + + S+ ++G ST T+ S ++ ST T
Sbjct: 270 SSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQT 329

Query: 1312 SLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQ 1371
+ S T+G S + S+ + ST T+ S T+ S ++ GS +
Sbjct: 330 AQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYG 389

Query: 1372 STSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTST------STSLSGSESTST 1425
ST T+ + S + ST T+ +S+ T+G S +Q S ST +G +S+
Sbjct: 390 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 449

Query: 1426 SSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSL 1485
+ S ++ DS+ T+ S+ T+ S + STST+ +S+ + S T+
Sbjct: 450 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYG 509

Query: 1486 SDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTST 1545
S ++ GST + ++S + S ST+ ++S+ + S+ T+ S+ + ST T
Sbjct: 510 STLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQT 569

Query: 1546 SLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSD 1605
+ GS+ T+ S + S S + S +++ S+ + ST T+ S T+
Sbjct: 570 AREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYG 629

Query: 1606 STSTSLSDSSSTSGSTSLSDSESTSTSTSESSSDSTSTSLSDSSSMSGSTSLSDSESTST 1665
STST+ +DSS +G S + S T+ S T+ SD ++ GSTS + ++S+
Sbjct: 630 STSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLI 689

Query: 1666 STSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSESTSASTSLSDSTSTSTSLSDSTSTSL 1725
+ S T+ +S T+ S+ T S S S ST+ +DS+ + S T++
Sbjct: 690 AGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYH 749

Query: 1726 SDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTST 1785
S ++ GST + +S T+ S ST+ +DS+ + S+ T+G S+ + ST T
Sbjct: 750 SSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQT 809

Query: 1786 SLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSD 1845
+ S T+ STS + + S+ + S + S +G ST T+ SD ++
Sbjct: 810 AQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYG 869

Query: 1846 STSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLSDSS 1905
STST+ DSS +G S + S T+ GS T+ S + S ST+ S
Sbjct: 870 STSTAGYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLI 929

Query: 1906 STSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSD 1965
+ GST + +ST + S T+ S+ T+ S+S +G S + ST T+
Sbjct: 930 AGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQ 989

Query: 1966 STSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGST 2025
ST T+ ST ++ SST + S + + + S+ ++ S+ S S + S
Sbjct: 990 STLTAGYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLI 1049

Query: 2026 SLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTSTSD 2085
S S T+ S S S T+ S+ ++ S+ ++ EST + + S +
Sbjct: 1050 SGLRSVLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKG 1109

Query: 2086 STSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSS 2134
S+ T+ S+ SG+ S+ + + +DST T+ S L+ ++S
Sbjct: 1110 SSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNS 1158



Score = 69.8 bits (170), Expect = 2e-13
Identities = 267/1081 (24%), Positives = 466/1081 (43%), Gaps = 4/1081 (0%)

Query: 1243 TSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSNSQSTSTSTSLSGSESTSTSSSLSDS 1302
TS + + + + + S ++ + + T + S S+ + +
Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158

Query: 1303 SSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTS 1362
+ ST S + S + +ST ++ ST + + ST + S+ T+
Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218

Query: 1363 GSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSES 1422
G S + ST T + S T+ ST + S+ + S + S+ +G S
Sbjct: 219 GEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 278

Query: 1423 TSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTS 1482
T T+ SD ++ ST T+ +DSS +G S + ST T+ ST T+ S T+
Sbjct: 279 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 338

Query: 1483 TSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTS 1542
S ++ S+ ++ ST T+ S T+ ST T+ S T+G S + + S
Sbjct: 339 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADS 398

Query: 1543 TSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTS 1602
+ + GS T+ S + S T+ SD ++ GST + S+ + S T+
Sbjct: 399 SLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTA 458

Query: 1603 TSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSDSTSTSLSDSSSMSGSTSLSDSES 1662
DS+ T+ S+ T+ S + STST+ S + S ++ GST + S
Sbjct: 459 GEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGS 518

Query: 1663 TSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSESTSASTSLSDSTSTSTSLSDSTS 1722
T T+ + SD + STST+ ++SS G S + S T+ ST T+ SD T+
Sbjct: 519 TQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTA 578

Query: 1723 TSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSGSTSLSDSESTS 1782
S ++ S S+ ++G ST T++ S+ T+ ST T+ S T+G S S + + S
Sbjct: 579 GYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADS 638

Query: 1783 TSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSS 1842
+ + ST T+ S + ST + SD + STS +G++S+ + S ++
Sbjct: 639 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTA 698

Query: 1843 TSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLS 1902
+S T+ S+ T+ S S STST+ + S + S ++ S T+ S
Sbjct: 699 GYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGS 758

Query: 1903 DSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTS 1962
++ S + STST+ + S + ST T+ S T+G S ++ S T+
Sbjct: 759 TQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTT 818

Query: 1963 LSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMS 2022
STST+ + S+ ++ ST + S + ST + S + S S + S
Sbjct: 819 GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDS 878

Query: 2023 GSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTS 2082
+ GS T+ +S+ + S T+ SD ++ GSTS + ES+ + S+ T+
Sbjct: 879 SLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTA 938

Query: 2083 TSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSMS 2142
+ ST + SS T+ S + STS + DS+ + ST ++ ST +
Sbjct: 939 SFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQ----TAGYQSTLTA 994

Query: 2143 SSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGSTSMISSESTSTSTSGSTSTSNSTSTS 2202
ST T+ S + GST+T+ +DSS +G S ++S S T+G ST S S
Sbjct: 995 GYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRS 1054

Query: 2203 LSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTS 2262
+ + S S S T+ S ++ S+ + S + + S ++G S+ T+
Sbjct: 1055 VLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTA 1114

Query: 2263 TSLSDSTSTSDSTSTSLSDSSSMSGSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSS 2322
S S +DS + ++G+ S + S + ++S T+ S T+ +
Sbjct: 1115 GYRSTLISGADSVQMAGERGKLIAGADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDC 1174

Query: 2323 T 2323

Sbjct: 1175 I 1175



Score = 68.2 bits (166), Expect = 4e-13
Identities = 256/1032 (24%), Positives = 438/1032 (42%), Gaps = 2/1032 (0%)

Query: 1385 TSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLS 1444
T S + + + + + S + + D +T +S ST +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 1445 DSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTS 1504
+ + S S + ST T+ +S + S ++ + ST ++ ST
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1505 TSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSS 1564
T+ S + ST T + S T+G S + S+ + GS T+ S +
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1565 TSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLS 1624
S T+ SD ++ GST + + S+ + S T+ +ST T+ S+ T+ S
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1625 DSESTSTSTSESSSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLS 1684
+ ST T+ S + S ++ S+ + ST T+ SD T+ ST T+ +
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 1685 DSSSTNGSTSLSDSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTS 1744
DSS G S + S T+ ST T+ SD T+ S ++ S+ ++G ST
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 1745 TSTSLSNSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDS 1804
T+ S+ T+ ST T+ S T+G S S + S+ + ST T+ ST +
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 1805 SSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLS 1864
ST + + SD + STS +G+ S+ + S +++ +S T+ S+ T+ S
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 1865 DSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTS 1924
+ ST T+ S S + S ++ S T+ S ++ S + STST+ +
Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636

Query: 1925 LSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTS 1984
S + ST T+ +S T+G S ++ S T+ STST+ + S+ ++ ST
Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGST- 695

Query: 1985 GSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDSTS 2044
T+ +S T+ S + SD TS S S++ + S+ ++G ST +S S T+
Sbjct: 696 -QTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTA 754

Query: 2045 TSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLS 2104
ST T+ S T+G S S + + S+ + ST T+ S + ST + S
Sbjct: 755 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERS 814

Query: 2105 DSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTS 2164
D + STS + + S+ + S + S T+ S T+ +S + S ST+
Sbjct: 815 DLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTA 874

Query: 2165 TSLSDSSSTSGSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSAS 2224
S + GST S T+ GST T+ S + STS + S + S
Sbjct: 875 GYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGS 934

Query: 2225 TSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDSSS 2284
T + ST + S + S T+ GS S + S + S T+ S ++
Sbjct: 935 TQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTA 994

Query: 2285 MSGSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTS 2344
GST ++ ST T+ S++ + +DS+ + SS TS S T+ S+ SG S
Sbjct: 995 GYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRS 1054

Query: 2345 LSDSVSTSTSSSLSDSTSLSGSVSTSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHS 2404
+ + S+ S S+ +G S ++ SS I+ +ST + + S ++ S +
Sbjct: 1055 VLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTA 1114

Query: 2405 HTNSISISDSTS 2416
S IS + S
Sbjct: 1115 GYRSTLISGADS 1126



Score = 67.9 bits (165), Expect = 6e-13
Identities = 268/1049 (25%), Positives = 451/1049 (42%), Gaps = 6/1049 (0%)

Query: 939 TSSSTSASDSASTSSSTSASLSGSQSASTSTSTSSKLSDSASASTSASDSTSSSTSASDS 998
T +S + + + + S ++ K+ + + T D+T S S +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 999 ASTSRSTSASLSGSQSASTSTSLSDSTSTSDSTSLSDSQSKSASTSLSDSSSTSGSTSLS 1058
+ +T S S + ST T+ +S + S T+ +DS+ +G S
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1059 DSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSTSLSNSSSTSGSTSLSDSQSTSTSTS 1118
+ S+ + GS T S + S T+ S+ + GST + S+ T+
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1119 LSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDS 1178
S T+ S T+ S+ T+G+ S + ST T+ +ST T+ S T+ SD
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1179 SSTSGSTSLSDSQSTST----STSLSGSESTSMSSSLSDSSSTSDSTSTSLSDSSSTSGS 1234
++ GST + S+ ST +G +S+ + S ++ S T+ S+ T+G+
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 1235 TSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSNSQSTSTSTSLSGSESTS 1294
S + ST T+ +ST T+ ST + S + S + S+ ++G ST
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 1295 TSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTS 1354
T+ S ++ ST T+ S T+G S S + S+ + ST T+ S T+
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 1355 LSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTS 1414
S ++ + S ++ STST+ + S + ST T+ +S T+G S ++ S
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 1415 TSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTS 1474
T+ G ST T+ S S + ST T+ SS T+G S + S T+ STST+
Sbjct: 577 TA--GYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTA 634

Query: 1475 DSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTS 1534
+ S + S ++ S + ST T+ SD T+ STST+ +DSS +G S
Sbjct: 635 GADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGS 694

Query: 1535 LSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTS 1594
+ S T+ GS T+ S S S ST+ + S + GST + S+ T+
Sbjct: 695 TQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTA 754

Query: 1595 TSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSDSTSTSLSDSSSMSGS 1654
S T+ S T+ S+ST+G+ S + ST T+ S T+ S ++ S
Sbjct: 755 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERS 814

Query: 1655 TSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSESTSASTSLSDSTSTS 1714
+ STST+ + S + ST T+ +S T G S ++ S T+ STST+
Sbjct: 815 DLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTA 874

Query: 1715 TSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSGSTS 1774
S + S ++ S +G ST T+ S+ T+ STST+ +SS +G S
Sbjct: 875 GYDSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGS 934

Query: 1775 LSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTS 1834
+ ST + S+ T+ S+ + STS + S + ST +G +ST T+
Sbjct: 935 TQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTA 994

Query: 1835 SSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTS 1894
S ++ ST T+ S++T+G+ S + S+ TS S T+ S S S
Sbjct: 995 GYGSTQTAEHSSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRS 1054

Query: 1895 DSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDS 1954
T+ S S S+ + S ++ S + +ST + + S +G S +
Sbjct: 1055 VLTAGYGSSLISGRRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTA 1114

Query: 1955 ESTSTSTSLSDSTSTSDSTSTSLSDSSST 1983
ST S +DS + ++ + ST
Sbjct: 1115 GYRSTLISGADSVQMAGERGKLIAGADST 1143



Score = 62.5 bits (151), Expect = 2e-11
Identities = 257/1011 (25%), Positives = 428/1011 (42%), Gaps = 6/1011 (0%)

Query: 852 SQSTSTITSTSTSNSTSNSNSISASNSTSTSLSDSKSNSLSASTSTSASTSNSTSASLSG 911
+ + S ++ + T + +S S + + +T ST +
Sbjct: 114 ACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQ 173

Query: 912 SQSASTSASTSSKLSDSASASTSASDSTSSSTSASDSASTSSSTSASLSGSQSASTSTST 971
SQ + ST + S + S T+ + S + S+ T+ S + ST T
Sbjct: 174 SQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQT 233

Query: 972 SSKLSDSASASTSASDSTSSSTSASDSASTSRSTSASLSGSQSASTSTSLSDSTSTSDST 1031
K SD + S + S+ + ST + S + ST T+ S T+
Sbjct: 234 GMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYG 293

Query: 1032 SLSDSQSKSASTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDST 1091
S + + S+ + S+ T+G S + ST T+ GS+ T+ S + S
Sbjct: 294 STGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLI 353

Query: 1092 STSLSNSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSEST 1151
+ S ++ S+ + ST T+ SD T+ ST T+ +DSS +G S +
Sbjct: 354 AGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEE 413

Query: 1152 STSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSMSSSL 1211
ST T+ ST T+ S T+ S ++ S+ ++ ST T+ G +S+ +
Sbjct: 414 STQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTA----GEDSSLTAGYG 469

Query: 1212 SDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSG 1271
S ++ S T+ S+ST+G S + ST T+ ST T+ ST + + S
Sbjct: 470 STQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLI 529

Query: 1272 STSLSNSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSEST 1331
+ S S + + S+ ++G ST T+S S ++ ST T+ S T+G S + S
Sbjct: 530 TGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSD 589

Query: 1332 STSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTST 1391
S+ + ST T+ S T+ S ++ S + STST+ + S + ST T
Sbjct: 590 SSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQT 649

Query: 1392 SLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSG 1451
+ +S T+G S +Q S T+ G STST+ + S + ST T+ +S T+G
Sbjct: 650 AGYNSILTAGYGSTQTAQEGSDLTA--GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAG 707

Query: 1452 STSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSD 1511
S ++ S TS STST+ + S + S +++ S+ + ST T+ S
Sbjct: 708 YGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQSV 767

Query: 1512 STSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTST 1571
T+ STST+ +DSS +G S + S T+ GS T+ S + S ST+
Sbjct: 768 LTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAG 827

Query: 1572 SLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTST 1631
+ S + GST + S T+ S T+ +S T+ S+ST+G S + ST
Sbjct: 828 ADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGST 887

Query: 1632 STSESSSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNG 1691
T+ +S T+ S ++ S + STST+ S + ST T+ S+ G
Sbjct: 888 QTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAG 947

Query: 1692 STSLSDSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSN 1751
S + S+ T+ STS + S + S ++ ST +G ST T+ S
Sbjct: 948 YGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSST 1007

Query: 1752 STSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGST 1811
T+ ST+T+ +DSS +G S S S T+ ST S S + S+ S
Sbjct: 1008 LTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLISG 1067

Query: 1812 SLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTS 1862
S + S ++ S+ + S + + S + SS T+G S
Sbjct: 1068 RRSSLTAGYGSNQIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRS 1118



Score = 60.9 bits (147), Expect = 8e-11
Identities = 261/1079 (24%), Positives = 450/1079 (41%), Gaps = 8/1079 (0%)

Query: 788 TTDTVTGLPPGLTYDPSTKTVSGTPSQLGSYTVTVTSKDASNNTTTKTFTWNIERNAASD 847
+ D + + G P T + T + +T + T + S
Sbjct: 124 SPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGST 183

Query: 848 SLSNSQSTSTITSTSTSNSTSNSNSISASNSTSTSLSDSKSNSLSASTSTSASTSNSTSA 907
+ ST ST + ++S ++ ST T+ +S + ST T S+ T+
Sbjct: 184 ETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTA- 242

Query: 908 SLSGSQSASTSASTSSKLSDSASASTSASDSTSSSTSASDSASTSSSTSASLSGSQSAST 967
G S T+ SS ++ S T+ DS+ ++ S + S + GS +
Sbjct: 243 ---GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAG 299

Query: 968 STSTSSKLSDSASASTSASDSTSSSTSASDSASTSRSTSASLSGSQSASTSTSLSDSTST 1027
+ S+ S + S T+ S + S T+ S + S+ ++ ST
Sbjct: 300 ADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGST 359

Query: 1028 SDSTSLSDSQSKSASTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTST 1087
+ S + ST + S + S + + S+ ++G ST T+ S T+
Sbjct: 360 QTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAG 419

Query: 1088 SDSTSTSLSNSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSD 1147
ST T+ S T+G S + S+ + ST T+ S+ + ST + SD
Sbjct: 420 YGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSD 479

Query: 1148 SESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSM 1207
+ STS + S+ + GST T+ S+ T+G S +Q+ S + GS ST+
Sbjct: 480 LTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAG 539

Query: 1208 SSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSS 1267
++S + S T++ S ++ GST + S T+ S T+ SDS+ + S+
Sbjct: 540 ANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGST 599

Query: 1268 STSGSTSLSNSQSTSTSTSLSGSEST----STSSSLSDSSSTSDSTSTSLSDSSSTSGST 1323
T+ S + ST T+ S T STS++ +DSS + ST + +S +
Sbjct: 600 QTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAG 659

Query: 1324 SLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSDST 1383
S + S + STS + + S+ + S+ T+G S+ + ST T+ S
Sbjct: 660 YGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSD 719

Query: 1384 STSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSL 1443
TS STS + + S+ + S ++ S+ +G ST T+ S ++ STST+
Sbjct: 720 LTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAG 779

Query: 1444 SDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSGSTSTSLSDSSSTSGSTSLSDSQST 1503
+DSS +G S + S T+ ST T+ S T+ S S++ + S+ ++ ST
Sbjct: 780 ADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGST 839

Query: 1504 STSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSS 1563
T+ S T+ ST T+ +S T+G S S + S+ + GS T+ +S+ +
Sbjct: 840 QTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAG 899

Query: 1564 STSDSTSTSLSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSL 1623
S T+ SD ++ GSTS + S+ + S T++ ST + SS T+ S
Sbjct: 900 YGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSS 959

Query: 1624 SDSESTSTSTSESSSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSL 1683
+ STS + S + S ++ ST + ST T+ S T+ ST+T+
Sbjct: 960 LTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATAG 1019

Query: 1684 SDSSSTNGSTSLSDSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSEST 1743
+DSS G S S S T+ ST S S T+ S S S+ +G S
Sbjct: 1020 ADSSLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLISGRRSSLTAGYGSN 1079

Query: 1744 STSTSLSNSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSD 1803
++ S+ + +ST + + S +G S + ST S +DS + ++
Sbjct: 1080 QIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAG 1139

Query: 1804 SSSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTS 1862
+ ST + S + + S +G S T+ + + S T+ +S T+G S
Sbjct: 1140 ADSTQTAGDRSKLLAGNNSYLTAGDRSKLTAGNDCILMAGDRSKLTAGINSILTAGCRS 1198



Score = 60.2 bits (145), Expect = 1e-10
Identities = 236/927 (25%), Positives = 403/927 (43%), Gaps = 6/927 (0%)

Query: 1513 TSTSDSTSTSLSDSSSTSGSTSLSDSQSTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTS 1572
T TS + + + + S ++ + + + D++ S ST +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 1573 LSDSSSTSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTS 1632
+ +T GST S + S T+ ST + S+ T+G+ S + ST
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1633 TSESSSDSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGS 1692
T+ S + S + M GS + ST T+ S + ST T+ DSS T G
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1693 TSLSDSESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNS 1752
S ++ S T+ ST T+ + S + S ++ ST +G ST T+ S+
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1753 TSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTS 1812
T+ ST T+ DSS +G S + S+ T+ ST T+ S + ST + +
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 1813 LSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTS 1872
S + ST +G EST T+ S ++ S T+ S+ T+G S + ST
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 1873 TSLSGSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTS 1932
T+ S T+ S + SD T+ S S++ S+ ++ ST T+ S T+
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 1933 DSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDS 1992
ST T+ ++S +G S S + + S+ + ST T+ S + ST + SD
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 1993 ESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTS 2052
+ ST + S S+ + S +S S T+ GS T+ S+ + S ST+ +
Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636

Query: 2053 LSDSSSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTS 2112
S + GST + S T+ S+ T+ S T+ S+ST+G+ S + ST
Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696

Query: 2113 TSLSDSTSTSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSS 2172
T+ +S T+ ST + S S S+S + + SS ++ ST ++ S +
Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756

Query: 2173 TSGSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSL--SDSQSTSASTSLSDS 2230
S T+ S T+ S ST+ ++S+ + S+ T+G S+ + ST + SD
Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816

Query: 2231 TSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTST----SDSTSTSLSDSSSMS 2286
T+ STST+ +DSS ++G S + S T+ ST T SD T+ S S++
Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876

Query: 2287 GSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTSLS 2346
S+ ++ ST T+ S + ST T+ S T+ STST+ +SS +G S
Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQ 936

Query: 2347 DSVSTSTSSSLSDSTSLSGSVSTSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHSHT 2406
+ ST + S+ + S+ T+ S+S++ DS+ + S + S +
Sbjct: 937 TASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGY 996

Query: 2407 NSISISDSTSSSDSNSNSMSDSASVST 2433
S ++ +S+ + S + + + S+
Sbjct: 997 GSTQTAEHSSTLTAGYGSTATAGADSS 1023



Score = 57.5 bits (138), Expect = 7e-10
Identities = 225/925 (24%), Positives = 403/925 (43%), Gaps = 14/925 (1%)

Query: 1579 TSGSTSLSDSVSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSS 1638
TS + + + + + S ++ + + + T D+ S ST + +
Sbjct: 99 TSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQT 158

Query: 1639 DSTSTSLSDSSSMSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDS 1698
+T S S S ++ ST T+ S + ST T+ +DS+ G S +
Sbjct: 159 IEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTA 218

Query: 1699 ESTSASTSLSDSTSTSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDS 1758
S+ + ST T SD T+ S ++ S+ ++G ST T+ S+ T+ S
Sbjct: 219 GEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGS 278

Query: 1759 TSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSES 1818
T T+ S T+G S + + S+ + ST T+ ST + ST + SD +
Sbjct: 279 TQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTA 338

Query: 1819 TSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGS 1878
ST +G +S+ + S ++ DS+ T+ S+ T+ S + ST T+ + S
Sbjct: 339 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADS 398

Query: 1879 ESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTS 1938
+ S + S T+ S ++ GS + ST T+ S + ST T+
Sbjct: 399 SLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTA 458

Query: 1939 LSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTS 1998
DSS T+G S ++ S T+ STST+ S+ ++ ST + S + S
Sbjct: 459 GEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGS 518

Query: 1999 TSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSS 2058
T + + S + S S + + S + GS T++ +S+ + S T+ SD ++
Sbjct: 519 TQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTA 578

Query: 2059 TSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDS 2118
GST + S+S+ + S+ T++ S+ T+ S+ T+ S+ + STST+ +DS
Sbjct: 579 GYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADS 638

Query: 2119 TSTSD--STSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTS-- 2174
+ + ST T+ +S T+G S +++ S ++ S ST+G+ S+ ++ ST
Sbjct: 639 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTA 698

Query: 2175 ----------GSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSAS 2224
GST S TS GSTST+ + S+ ++ ST ++ S + S
Sbjct: 699 GYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGS 758

Query: 2225 TSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDSSS 2284
T + S + S S + + S + GS T+ S+ + S T+ SD ++
Sbjct: 759 TQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTT 818

Query: 2285 MSGSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTS 2344
GSTS + + S+ + S+ + +S T+ S+ T+ NS T+ S+ST+G S
Sbjct: 819 GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDS 878

Query: 2345 LSDSVSTSTSSSLSDSTSLSGSVSTSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHS 2404
+ ST ++ +S +G ST T+ S + STST+ +S+ ++ S +
Sbjct: 879 SLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTA 938

Query: 2405 HTNSISISDSTSSSDSNSNSMSDSASVSTSDTPSHSHSFSQSVSSSGSTSSSDSNSHSAS 2464
S ++ SS + S + STS S + S+ + S + S
Sbjct: 939 SFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGS 998

Query: 2465 MSTSEKPSESISHSQSTSASTSDST 2489
T+E S + ST+ + +DS+
Sbjct: 999 TQTAEHSSTLTAGYGSTATAGADSS 1023



Score = 53.2 bits (127), Expect = 1e-08
Identities = 211/871 (24%), Positives = 369/871 (42%), Gaps = 6/871 (0%)

Query: 1652 SGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTNGSTSLSDSESTSASTSLSDST 1711
S + + + + + S ++ + + + T D+ S ST + +
Sbjct: 100 SAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTI 159

Query: 1712 STSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSG 1771
+T S + T S + GST +G ST + S T+ +DST + S+ T+G
Sbjct: 160 EIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAG 219

Query: 1772 STSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSEST 1831
S + ST T + S T+ ST + S+ + S + S+ +G ST
Sbjct: 220 EESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGST 279

Query: 1832 STSSSLSDSSSTSDSTSTSLSDSS--STSGSTSLSDSESTSTSTSLSGSESTSTSTSLSD 1889
T+ SD ++ ST T+ +DSS + GST + EST T+ S + S +
Sbjct: 280 QTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAG 339

Query: 1890 STSTSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGST 1949
ST + S + S T+ DS T+ S + SD T+ S ++ + S+
Sbjct: 340 YGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSS 399

Query: 1950 SLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSD 2009
++ ST T+ S T+ ST T+ S T+G S + S+ + ST T+
Sbjct: 400 LIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAG 459

Query: 2010 STSTSL----SDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSL 2065
S+ S ++ GS +G STS + S + ST T+ S+ T+G S
Sbjct: 460 EDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGST 519

Query: 2066 SDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDST 2125
+++ S + STST+ + S+ ++ ST ++ S + ST + S +
Sbjct: 520 QTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAG 579

Query: 2126 STSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGSTSMISSEST 2185
S + S S + S T++ S + S T+ S ++ GSTS ++S+
Sbjct: 580 YGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSS 639

Query: 2186 STSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSS 2245
+ GST T+ S + ST + SD + STS + + S+ + S +
Sbjct: 640 LIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAG 699

Query: 2246 SMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSDSVSTSTSTSESS 2305
S T+ GS T+ S S S ST+ + S + GST + S+ T+ S+
Sbjct: 700 YNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGST 759

Query: 2306 SISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTSLSDSVSTSTSSSLSDSTSLSG 2365
+ S T+ S+ST+ ++S+ + S+ T+G S+ + ST ++ S +G
Sbjct: 760 QTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDLTTG 819

Query: 2366 SVSTSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHSHTNSISISDSTSSSDSNSNSM 2425
STST+ ++SS I+ ST T+ +S + S + NS + S+S + +S
Sbjct: 820 YGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSS 879

Query: 2426 SDSASVSTSDTPSHSHSFSQSVSSSGSTSSSDSNSHSASMSTSEKPSESISHSQSTSAST 2485
+ ST +S + S+ + +SD + S ST+ S I+ ST ++
Sbjct: 880 LIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTAS 939

Query: 2486 SDSTSQSMSHSMSASSSESTNVSPMHPTSEA 2516
ST + S + +S+ + TS A
Sbjct: 940 FKSTLMAGYGSSQTAREQSSLTAGYGSTSMA 970



Score = 49.8 bits (118), Expect = 2e-07
Identities = 197/811 (24%), Positives = 348/811 (42%), Gaps = 6/811 (0%)

Query: 1713 TSTSLSDSTSTSLSDSSSTSGSTSLSGSESTSTSTSLSNSTSTSDSTSTSLSDSSSTSGS 1772
T TS +D + + + GS ++ + N + + +S ST +
Sbjct: 97 TKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPT 156

Query: 1773 TSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTS 1832
++ + ST + S + ST + SST + S + + ST ++G ST
Sbjct: 157 QTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQ 216

Query: 1833 TSSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTS 1892
T+ S + ST T + S T+G S + S+ + GS T+ S +
Sbjct: 217 TAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGY 276

Query: 1893 TSDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLS 1952
S T+ SD ++ GST + + S+ + S T+ +ST T+ S+ T+ S
Sbjct: 277 GSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDL 336

Query: 1953 DSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTS 2012
+ ST T+ DS+ + ST + S+ + S + S + ST + +
Sbjct: 337 TAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGA 396

Query: 2013 TSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTS 2072
S + S T+ S T+ S + SD T+ S ++ S+ ++ ST
Sbjct: 397 DSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQ 456

Query: 2073 TSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDS 2132
T+ +SS T+ ST T+ S T+G S S + S+ + ST T+ ST +
Sbjct: 457 TAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGY 516

Query: 2133 SST----SGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSSTSGSTSMISSESTSTS 2188
ST + S ++ STST+ + S + GST T+ +S T+G S ++ S
Sbjct: 517 GSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDL 576

Query: 2189 TSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSSSMS 2248
T+G ST + S S + S T+ S T+ S + S T+ S S++ +
Sbjct: 577 TAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGA 636

Query: 2249 GSTSLSGSVSTSTSTSLSDSTSTSDSTSTSL--SDSSSMSGSTSLSDSVSTSTSTSESSS 2306
S+ ++G ST T+ S T+ ST T+ SD ++ GSTS + + S+ + S+
Sbjct: 637 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQ 696

Query: 2307 ISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTSLSDSVSTSTSSSLSDSTSLSGS 2366
+ +S T+ S+ T+ S TS S+ST+G+ S + ST ++ S+ +G
Sbjct: 697 TAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGY 756

Query: 2367 VSTSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHSHTNSISISDSTSSSDSNSNSMS 2426
ST T+ +S + STST+ +DS+ ++ S + +SI + S+ + S
Sbjct: 757 GSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQERSDL 816

Query: 2427 DSASVSTSDTPSHSHSFSQSVSSSGSTSSSDSNSHSASMSTSEKPSESISHSQSTSASTS 2486
+ STS + S + S+ + +S + S T+++ S+ + STS +
Sbjct: 817 TTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGY 876

Query: 2487 DSTSQSMSHSMSASSSESTNVSPMHPTSEAQ 2517
DS+ + S + S + T AQ
Sbjct: 877 DSSLIAGYGSTQTAGYNSILTAGYGSTQTAQ 907



Score = 44.7 bits (105), Expect = 6e-06
Identities = 161/717 (22%), Positives = 290/717 (40%)

Query: 1801 LSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSSSLSDSSSTSDSTSTSLSDSSSTSGS 1860
+ +S ++ + + +G S +S + + + T + S S
Sbjct: 95 VGTKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQ 154

Query: 1861 TSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDSQSTS 1920
+ + +T ST +S + S T+ ST + S+ T+G+ S + S
Sbjct: 155 PTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGS 214

Query: 1921 TSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDS 1980
T T+ +S+ + ST S + S + S+ ++ ST + S +
Sbjct: 215 TQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTA 274

Query: 1981 SSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSASSSLS 2040
S T+ S+ T+ S + + S + S ++ ST +G ST + S
Sbjct: 275 GYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGS 334

Query: 2041 DSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSSTSGS 2100
D T+ ST T+ DSS +G S + S+ T+ ST T+ S + ST +
Sbjct: 335 DLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTA 394

Query: 2101 TSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSMSSSESTSTSSSLSDSNSTS 2160
+ S + ST + ST + S + S T+ S T+ S + S
Sbjct: 395 GADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGS 454

Query: 2161 GSTSTSLSDSSSTSGSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQS 2220
T+ S ++ GST S T+ GSTST+ S+ ++ ST + S +
Sbjct: 455 TQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTA 514

Query: 2221 TSASTSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLS 2280
ST + + S + S S + + S + GS T++ S+ + S T+ S
Sbjct: 515 GYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGS 574

Query: 2281 DSSSMSGSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTSTSLSDSSSTS 2340
D ++ GST + S S+ + S+ ++ S+ T+ S+ T+ S T+ S+ST+
Sbjct: 575 DLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTA 634

Query: 2341 GSTSLSDSVSTSTSSSLSDSTSLSGSVSTSTSTSESSSISTSDSTSTSTSDSASMSTSDS 2400
G+ S + ST ++ +S +G ST T+ S + STST+ +DS+ ++ S
Sbjct: 635 GADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGS 694

Query: 2401 QSHSHTNSISISDSTSSSDSNSNSMSDSASVSTSDTPSHSHSFSQSVSSSGSTSSSDSNS 2460
+ NSI + S+ + S S STS + S + S+ ++ S +
Sbjct: 695 TQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTA 754

Query: 2461 HSASMSTSEKPSESISHSQSTSASTSDSTSQSMSHSMSASSSESTNVSPMHPTSEAQ 2517
S T+ + S + STS + +DS+ + S + S + T AQ
Sbjct: 755 GYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYHSILTAGYGSTQTAQ 811



Score = 38.2 bits (88), Expect = 6e-04
Identities = 162/692 (23%), Positives = 289/692 (41%), Gaps = 6/692 (0%)

Query: 1834 SSSLSDSSSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTST 1893
+D + ++ + S ++ T + S ST + ++ +T
Sbjct: 106 LHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPVTDDIDATIESGSTQPTQTIEIATYG 165

Query: 1894 SDSTSASLSDSSSTSGSTSLSDSQSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTS--L 1951
S + S + GST + ST + S T+ +DST + S+ T+G S +
Sbjct: 166 STLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTGTAGADSTLVAGYGSTQTAGEESSQM 225

Query: 1952 SDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDST 2011
+ ST T SD T+ ST T+ DSS +G S + S+ T+ ST T+
Sbjct: 226 AGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKG 285

Query: 2012 STSLSDSSSMSGSTSLSGSESTSASSSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSEST 2071
S + S + + S + S+ + ST + S + S T+ S T
Sbjct: 286 SDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGT 345

Query: 2072 STSTSESSSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSD 2131
+ S + S T+ S ++ GST + S T+ S T+ +DS+ +
Sbjct: 346 AGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYG 405

Query: 2132 SSSTSGSTSMSSSESTSTSSSLSDSNSTSGSTSTSLSDSSST----SGSTSMISSESTST 2187
S+ T+G S ++ ST ++ S+ T+G ST + S+ GST +S+ T
Sbjct: 406 STQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLT 465

Query: 2188 STSGSTSTSNSTSTSLSDSSSTSGSTSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSSSM 2247
+ GST T+ S + STS + S + ST + ST + S + +
Sbjct: 466 AGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNE 525

Query: 2248 SGSTSLSGSVSTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSDSVSTSTSTSESSSI 2307
S + GS ST+ + S + S T++ S ++ GST + S T+ S+
Sbjct: 526 SDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGT 585

Query: 2308 STSDSTSTSTSESSSTSTSNSTSTSLSDSSSTSGSTSLSDSVSTSTSSSLSDSTSLSGSV 2367
+ SDS+ + S+ T++ +S+ T+ S+ T+ S+ + STS++ +DS+ ++G
Sbjct: 586 AGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYG 645

Query: 2368 STSTSTSESSSISTSDSTSTSTSDSASMSTSDSQSHSHTNSISISDSTSSSDSNSNSMSD 2427
ST T+ S + ST T+ S + S S + +S I+ S+ + NS+
Sbjct: 646 STQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILT 705

Query: 2428 SASVSTSDTPSHSHSFSQSVSSSGSTSSSDSNSHSASMSTSEKPSESISHSQSTSASTSD 2487
+ ST S S S+S + + S + S T+ S + ST +
Sbjct: 706 AGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTASYHSSLTAGYGSTQTAREQ 765

Query: 2488 STSQSMSHSMSASSSESTNVSPMHPTSEAQHH 2519
S + S S + ++S+ ++ T A +H
Sbjct: 766 SVLTTGYGSTSTAGADSSLIAGYGSTQTAGYH 797



Score = 36.3 bits (83), Expect = 0.002
Identities = 155/669 (23%), Positives = 273/669 (40%), Gaps = 6/669 (0%)

Query: 1857 TSGSTSLSDSESTSTSTSLSGSESTSTSTSLSDSTSTSDSTSASLSDSSSTSGSTSLSDS 1916
T G +E T S + + + + + S +S
Sbjct: 81 THGWIKFPRAEVLHVGTKTSAMQFILHHRADYVACTEMQAGPGSPDVTSEVKVGNRSLPV 140

Query: 1917 QSTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTS 1976
+T S ST + + + S+ + S + ST T+ ST + ST
Sbjct: 141 TDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGSTG 200

Query: 1977 LSDSSSTSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSMSGSTSLSGSESTSAS 2036
+ + ST + S + S+ ++ ST S + S T+ S +
Sbjct: 201 TAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAGY 260

Query: 2037 SSLSDSTSTSDSTSTSLSDSSSTSGSTSLSDSESTSTSTSESSSTSTSDSTSTSLSDSSS 2096
S + S T+ S ++ GS + ST T+ ++SS + ST T+ +S+
Sbjct: 261 GSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQ 320

Query: 2097 TSGSTSLSDSESTSTSTSLSDSTSTSDSTSTSLSDSSSTSGSTSMSSSE----STSTSSS 2152
T+G S ++ S T+ ST T+ S+ ++ ST + SS ST T+
Sbjct: 321 TAGYGSTQTAQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQK 380

Query: 2153 LSDSNSTSGSTSTSLSDSSSTSGSTSMISSESTSTSTSGSTSTSNSTSTSLSDSSSTSGS 2212
SD + GST T+ +DSS +G S ++ ST T+G ST + S + S
Sbjct: 381 GSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLTAGYGSTG 440

Query: 2213 TSLSDSQSTSASTSLSDSTSTSNSTSTSLSDSSSMSGSTSLSGSVSTSTSTSLSDSTSTS 2272
T+ DS + S + S+ T+ S ++ GS +G STST+ S +
Sbjct: 441 TAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYESSLIAGY 500

Query: 2273 DSTSTSLSDSSSMS--GSTSLSDSVSTSTSTSESSSISTSDSTSTSTSESSSTSTSNSTS 2330
ST T+ S+ + GST + + S + S+S + ++S+ + S+ T++ NS
Sbjct: 501 GSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTASYNSVL 560

Query: 2331 TSLSDSSSTSGSTSLSDSVSTSTSSSLSDSTSLSGSVSTSTSTSESSSISTSDSTSTSTS 2390
T+ S+ T+ S + ST ++ SDS+ ++G ST T++ SS + ST T+
Sbjct: 561 TAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTASYHSSLTAGYGSTQTARE 620

Query: 2391 DSASMSTSDSQSHSHTNSISISDSTSSSDSNSNSMSDSASVSTSDTPSHSHSFSQSVSSS 2450
S + S S + +S I+ S+ + NS+ + ST S + S+S
Sbjct: 621 QSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTS 680

Query: 2451 GSTSSSDSNSHSASMSTSEKPSESISHSQSTSASTSDSTSQSMSHSMSASSSESTNVSPM 2510
+ + S + S T+ S + ST + S S S S + ++S+ ++
Sbjct: 681 TAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGY 740

Query: 2511 HPTSEAQHH 2519
T A +H
Sbjct: 741 GSTQTASYH 749


3EL082_RS00660EL082_RS00690Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS00660215-2.714560PepSY domain-containing protein
EL082_RS00665515-3.935675DoxX family protein
EL082_RS00670815-4.902682D-alanyl-D-alanine carboxypeptidase
EL082_RS006751518-6.534193TIGR01741 family protein
EL082_RS006801518-7.369536tandem-type lipoprotein
EL082_RS00685713-4.511630tandem-type lipoprotein
EL082_RS00690515-2.923487tandem-type lipoprotein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00670BLACTAMASEA491e-08 Beta-lactamase class A signature.
		>BLACTAMASEA#Beta-lactamase class A signature.

Length = 286

Score = 49.4 bits (118), Expect = 1e-08
Identities = 60/325 (18%), Positives = 108/325 (33%), Gaps = 62/325 (19%)

Query: 1 MKKVFTSLMMIMMCLVLISPTVFAEQSPVDIAKQEHQDIDKQYNPK-GMIVT-TKDGQIL 58
M+ + + I+ L + V A P++ K + Q + + GMI G+ L
Sbjct: 1 MRYIR---LCIISLLATLPLAVHASPQPLEQIK----LSESQLSGRVGMIEMDLASGRTL 53

Query: 59 YDYHANTQVDPASTTKLMTMNLVYDNIKSGKIKMNDKVKITSRYEKMSELPNLTTFPLKE 118
+ A+ + ST K++ V + +G ++ K+ +L + + P+ E
Sbjct: 54 TAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQ-----QDLVDYS--PVSE 106

Query: 119 ---GTTVTINQLLKQAALESSNAATLVLAEHIDGSSSKFTDRMNQKAKDLGMKDTKFTNP 175
+T+ +L A S N+A +L + G + T + Q +G T+
Sbjct: 107 KHLADGMTVGELCAAAITMSDNSAANLLLATVGG-PAGLTAFLRQ----IGDNVTR---- 157

Query: 176 SGANNKILKPYEPKSYKDDTISHTTAREMS-LLSNHILNAHPDVLKITKLSKDKQS--NQ 232
L P +D TT M+ L + + +LS Q Q
Sbjct: 158 LDRWETELNEALPGDARDT----TTPASMAATLRKLLTS--------QRLSARSQRQLLQ 205

Query: 233 ELHNTNTSSPNEADGMKD--VDGLKTGTSDNGYNLELTAKRNHL----------RIVTGI 280
+ + + P + KTG + G R + RIV
Sbjct: 206 WMVDDRVAGPLIRSVLPAGWFIADKTGAGERG-------ARGIVALLGPNNKAERIVVIY 258

Query: 281 FNVKPYPDEQAKHARQKLANALTEH 305
P + + AL EH
Sbjct: 259 LRDTPASMAERNQQIAGIGAALIEH 283


4EL082_RS01850EL082_RS01975Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS01850211-4.173198hypothetical protein
EL082_RS0185509-2.925224glycosyltransferase family 2 protein
EL082_RS01860-19-1.620728glycosyltransferase family 2 protein
EL082_RS01865-280.123905phospho-sugar mutase
EL082_RS01870-290.553183(deoxy)nucleoside triphosphate
EL082_RS01875-2100.939064DEAD/DEAH box helicase
EL082_RS01880-2113.556690dihydrolipoyl dehydrogenase
EL082_RS01885-2113.093656thiamine pyrophosphate-dependent dehydrogenase
EL082_RS01890-1122.458086alpha-ketoacid dehydrogenase subunit beta
EL082_RS01895-1121.8130622-oxo acid dehydrogenase subunit E2
EL082_RS019000102.656085alpha/beta fold hydrolase
EL082_RS01905-2101.888997hypothetical protein
EL082_RS019100142.214012DUF1413 domain-containing protein
EL082_RS01915-2162.923673SDR family oxidoreductase
EL082_RS01920-2153.248915acetylornithine deacetylase
EL082_RS01925-2163.309934RNA degradosome polyphosphate kinase
EL082_RS01930-1163.081471exopolyphosphatase
EL082_RS01935-2173.668718AbgT family transporter
EL082_RS019400184.063847SDR family oxidoreductase
EL082_RS01945-1163.101587hypothetical protein
EL082_RS118950182.054369M42 family metallopeptidase
EL082_RS019500162.205759DUF1307 domain-containing protein
EL082_RS019601131.231876arsenate reductase (thioredoxin)
EL082_RS019651130.944333arsenite efflux transporter membrane subunit
EL082_RS019701130.623513helix-turn-helix transcriptional regulator
EL082_RS019752131.266109FMN-binding glutamate synthase family protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01855BCTERIALGSPD290.042 Bacterial general secretion pathway protein D signa...
		>BCTERIALGSPD#Bacterial general secretion pathway protein D

signature.
Length = 660

Score = 29.1 bits (65), Expect = 0.042
Identities = 11/75 (14%), Positives = 33/75 (44%), Gaps = 3/75 (4%)

Query: 323 KKGDKAEIITFIKWYSDKDDEQLQFKRNKAYYSYNNELFLKHMHVTLQNIIRKNNSITLK 382
KK K ++ FI+ +D ++ + + Y ++N+ + ++ ++ L+
Sbjct: 578 KKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQD---LLE 634

Query: 383 LYSKNSHIEFMELKS 397
+Y + F ++ +
Sbjct: 635 IYPRQDTAAFRQVSA 649


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01920DHBDHDRGNASE905e-24 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 90.5 bits (224), Expect = 5e-24
Identities = 53/189 (28%), Positives = 94/189 (49%), Gaps = 2/189 (1%)

Query: 4 LKDKVAVVTGAGSGIGEAIATALGNQGVKVVLAGRNTDKLNAV--ATKFDSNQVKVVATD 61
++ K+A +TGA GIGEA+A L +QG + N +KL V + K ++ + D
Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65

Query: 62 VTNQREVESLIDTAKTSFGGLDIVVNSAGQMKSSKITDYKVEDWDSMIDVNIKGTLYTVQ 121
V + ++ + + G +DI+VN AG ++ I E+W++ VN G +
Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125

Query: 122 AALPTLLEQSSGHIINIASISGFEVTKGSAIYSATKAAVHTITQGLEKELAKTGVKVTSI 181
+ ++++ SG I+ + S A Y+++KAA T+ L ELA+ ++ +
Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185

Query: 182 SPGMVETPL 190
SPG ET +
Sbjct: 186 SPGSTETDM 194


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01945DHBDHDRGNASE1322e-39 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 132 bits (332), Expect = 2e-39
Identities = 83/255 (32%), Positives = 131/255 (51%), Gaps = 7/255 (2%)

Query: 2 KRLENKVAVVTGASTGIGQASANVLAQEGAHVLALDIS-DQLDQTVEDIKQQGGQATAFQ 60
K +E K+A +TGA+ GIG+A A LA +GAH+ A+D + ++L++ V +K + A AF
Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63

Query: 61 VDISDEQQVQAFANQIKSEFGHVDVLFNNAGVDNGAGRIHEYPVEVFDKIMGVDMRGTFL 120
D+ D + +I+ E G +D+L N AGV G IH E ++ V+ G F
Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGVFN 122

Query: 121 VTKFLLPLMMDN-GGSIINTASFSGQAADLYRSGYNAAKGAVINFTKSIAIEYGRDNIRA 179
++ + MMD GSI+ S + Y ++K A + FTK + +E NIR
Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182

Query: 180 NAIAPGTIETPLVDNLAGTAQDEAGQTFR---ENQKWVTPLGRLGTPDEVGKLVTFLASD 236
N ++PG+ ET + +L ++ A Q + E K PL +L P ++ V FL S
Sbjct: 183 NIVSPGSTETDMQWSL-WADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241

Query: 237 DSSFITGETIRIDGG 251
+ IT + +DGG
Sbjct: 242 QAGHITMHNLCVDGG 256


5EL082_RS02030EL082_RS02055Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS020302130.753372ABC transporter permease
EL082_RS020352120.762763osmoprotectant ABC transporter substrate-binding
EL082_RS020403110.532050ABC transporter permease
EL082_RS020452100.540053antiholin-like protein LrgB
EL082_RS02050290.607319antiholin-like murein hydrolase modulator LrgA
EL082_RS02055290.230371MFS transporter
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02055TCRTETB961e-23 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 96.5 bits (240), Expect = 1e-23
Identities = 77/387 (19%), Positives = 157/387 (40%), Gaps = 27/387 (6%)

Query: 41 STYQSDIGTINIAVSLTALMSGLFIVGAGDFADKFGRVKVTYIGLILNIIGSLLIIIT-P 99
+ + +N A LT S V G +D+ G ++ G+I+N GS++ +
Sbjct: 45 NKPPASTNWVNTAFMLT--FSIGTAV-YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHS 101

Query: 100 FTPFLIAGRIFQGLSAACIMPATLAIINQYYIGTARQ-RALSYWSIGSWGGSGICTLFGG 158
F LI R QG AA PA + ++ YI + +A G G+ GG
Sbjct: 102 FFSLLIMARFIQGAGAAAF-PALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG 160

Query: 159 LMSTHFGWRTIFIVSIVLTLLSMYLIKHTPETKAEPVITENGEKKKFDIVGLMILIICML 218
+++ + W + ++ ++ + +L+K + E K FDI G++++ + ++
Sbjct: 161 MIAHYIHWSYLLLIPMITIITVPFLMKLLKK--------EVRIKGHFDIKGIILMSVGIV 212

Query: 219 SINVIITQTSKLGLFSPIILSLIVVFIVSLIGFIIYENKIKYPLVDFSLFSNKGYSGATV 278
+ T S S ++V ++S + F+ + K+ P VD L N + +
Sbjct: 213 FFMLFTTSYSI---------SFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL 263

Query: 279 SNFMLNGVAGGTLIVVNTYYQQQLDFNESQTG-MISLTYLIAVLIMIRVGEKILQALGPK 337
++ G G + +V + + ++ G +I ++V+I +G ++ GP
Sbjct: 264 CGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPL 323

Query: 338 RPLLMGSGITALGLVLLSLTFLPEPWYITSSVIGYLLFGTGLGIYATPSTDTAVAQAPDE 397
L +G ++ + S W++T ++ + G ST + + +
Sbjct: 324 YVLNIGVTFLSVSFLTASFLLETTSWFMTIIIV--FVLGGLSFTKTVISTIVSSSLKQ-Q 380

Query: 398 KVGVASGVYKMASSLGNAFGVAISGTI 424
+ G + S L G+AI G +
Sbjct: 381 EAGAGMSLLNFTSFLSEGTGIAIVGGL 407


6EL082_RS02710EL082_RS02765Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS027103110.569281PTS transporter subunit EIIC
EL082_RS02715111-0.625785hypothetical protein
EL082_RS027204120.339169bile acid:sodium symporter family protein
EL082_RS02725313-1.469573HAD-IA family hydrolase
EL082_RS027304110.153312hypothetical protein
EL082_RS02735190.839598hypothetical protein
EL082_RS027400101.053269hypothetical protein
EL082_RS027450100.938381amino acid permease
EL082_RS027501130.354750MurR/RpiR family transcriptional regulator
EL082_RS027551150.621370PTS transporter subunit EIIC
EL082_RS02760216-0.913382N-acetylmuramic acid 6-phosphate etherase
EL082_RS02765317-1.813419DUF871 family protein
7EL082_RS03410EL082_RS03460Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS03410213-0.384874iron chelate uptake ABC transporter family
EL082_RS03420115-1.956505YjiH family protein
EL082_RS03425216-2.341366heme oxygenase
EL082_RS03430315-3.389661hypothetical protein
EL082_RS03435515-2.663991metal-dependent hydrolase
EL082_RS03440312-1.727155UDPGP type 1 family protein
EL082_RS03445513-1.568013hemolysin III family protein
EL082_RS03450412-1.504756MFS transporter
EL082_RS03455415-1.784226SepA family multidrug efflux transporter
EL082_RS03460214-0.463099multidrug efflux MFS transporter
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03450TCRTETB1102e-28 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 110 bits (276), Expect = 2e-28
Identities = 92/396 (23%), Positives = 169/396 (42%), Gaps = 14/396 (3%)

Query: 12 LILIMFMAAIEASIISLAMPTIRQDLNA-GSFISLVFTAYFIALVIANPIVGELMSRFKI 70
L ++ F + + ++++++P I D N + + V TA+ + I + G+L + I
Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78

Query: 71 IYIAITGLVLFAIGSFMSGTSET-FMMLIISRVIQGFGAGVMMSLSQIVPKLAFEIPLRY 129
+ + G+++ GS + + F +LI++R IQG GA +L +V R
Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138

Query: 130 KIMGIVGSVWGVSSIIGPLLGGGILEIATWHWLFFINIPIAIIAIILVIFTFHFPEEEII 189
K G++GS+ + +GP +GG I HW + + IP+ I II V F ++E+
Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPM--ITIITVPFLMKLLKKEVR 194

Query: 190 SKTNFDVKGLSLFYVFIGLLMFSLLNQNQVLLNVLSLLLALLIGYILYKVEKTTDHPFLP 249
K +FD+KG+ L V I M + + L V L + + +I + PF+
Sbjct: 195 IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHI-----RKVTDPFVD 249

Query: 250 VVEF-NKSIALVFITDLLIAICLMGFNLYIPVYLQEQIGLSPLQSGF-VIFPLSVAWIIL 307
N + + +I + GF +P +++ LS + G +IFP +++ II
Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309

Query: 308 NFNLAKLEAKFSRKALYIGAFTFLIIGSIIIIFGIK-TPLLIAFSVILAGLSFGFVYTKD 366
+ L + + TFL + + F ++ T + ++ F T
Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVI 369

Query: 367 SVIVQEETSPHQMKKMMSFYALTKNLGSSIGSTVMG 402
S IV + MS T L G ++G
Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03460TCRTETB1349e-37 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 134 bits (339), Expect = 9e-37
Identities = 94/416 (22%), Positives = 188/416 (45%), Gaps = 14/416 (3%)

Query: 7 SKRRRNLIVSVMLISAFVAILNQTLLNTALPHIMRELKIDESTSQWLITGFMLVNGVMIP 66
S R N I+ + I +F ++LN+ +LN +LP I + +++ W+ T FML +
Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67

Query: 67 LTAYLMDRVKTRPLYLSAMGTFLIGSIVAAIAPN-FGVLMTARVIQAMGAGVLMPLMQFT 125
+ L D++ + L L + GS++ + + F +L+ AR IQ GA L+
Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127

Query: 126 LFTLFSRERRGFAMGLAGLVIQFAPAIGPTFTGLIIDHVSWRVPFIIIVGIALIALIFGF 185
+ +E RG A GL G ++ +GP G+I ++ W +++++ + I +
Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPFL 185

Query: 186 IFISSYNETKQTKLDKRSILYSTIGFGMMLYAFSSAGSLGFGNPIIIGTLIISLIIILIF 245
+ + + D + I+ ++G + F I LI+S++ LIF
Sbjct: 186 MKLLKKEVRIKGHFDIKGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIF 236

Query: 246 IRRQLTISNPLLNLKVFKTRTFCFSTITSMIVMMSMVGPALLIPLYVQNALALSALLSGL 305
++ +++P ++ + K F + I+ ++ G ++P +++ LS G
Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296

Query: 306 VIM-PGAIINGLMSVFTGSFYDKYGPRPLIISGFTILTICTFLLCFLKADTSYMYLIIIY 364
VI+ PG + + G D+ GP ++ G T L++ FL TS+ III
Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIV 356

Query: 365 AIRMFAVSLLMMPINTAGINALENKNISHGTAIMNFGRVMAGSLGTALMVTFMSMG 420
+ +S I+T ++L+ + G +++NF ++ G A++ +S+
Sbjct: 357 FVLGG-LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411


8EL082_RS03785EL082_RS03840Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS037852162.013046F0F1 ATP synthase subunit alpha
EL082_RS037903161.418751F0F1 ATP synthase subunit gamma
EL082_RS037951141.540353F0F1 ATP synthase subunit beta
EL082_RS03800215-0.072972F0F1 ATP synthase subunit epsilon
EL082_RS03805117-0.429390DUF1146 domain-containing protein
EL082_RS038103161.375469UDP-N-acetylglucosamine
EL082_RS038151140.5928503-hydroxyacyl-ACP dehydratase FabZ
EL082_RS038201120.781204YwpF-like family protein
EL082_RS038253120.708465single-stranded DNA-binding protein
EL082_RS038303130.890301transglycosylase family protein
EL082_RS038353150.631158thiaminase II
EL082_RS03840215-0.923846bifunctional hydroxymethylpyrimidine
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03810ECOLIPORIN290.044 E.coli/Salmonella-type porin signature.
		>ECOLIPORIN#E.coli/Salmonella-type porin signature.

Length = 383

Score = 28.7 bits (64), Expect = 0.044
Identities = 13/39 (33%), Positives = 21/39 (53%)

Query: 374 RAAAALILAGLVAEGTTQVTELKHLDRGYVDLHGKLKSL 412
R AL++ L+A G E+ + D +DL+GK+ L
Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGL 41


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03815PF07520300.005 Virulence protein SrfB
		>PF07520#Virulence protein SrfB

Length = 1041

Score = 29.6 bits (66), Expect = 0.005
Identities = 11/52 (21%), Positives = 22/52 (42%), Gaps = 3/52 (5%)

Query: 27 VEYEEGKRCVGLKQVSGNEPFFQGHFPDYAVMPGVLITEALAQTGAVAMLNS 78
V+ E G K+ + P + F ++ G ++ E +A A+ +N
Sbjct: 431 VKTEIGLNLRKPKKTTPLTPAIRPRFSRSSLF-GFMLAEVIAH--AMVQIND 479


9EL082_RS04175EL082_RS04220Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS04175014-4.358313hypothetical protein
EL082_RS04180212-4.124252GntR family transcriptional regulator
EL082_RS04190212-4.825149ABC transporter ATP-binding protein
EL082_RS04195312-5.546817ABC-2 transporter permease
EL082_RS04200013-5.226629phenol-soluble modulin export ABC transporter
EL082_RS04205112-5.654128ABC transporter permease
EL082_RS04210-111-4.597652thioredoxin family protein
EL082_RS04215113-4.691188hypothetical protein
EL082_RS04220114-4.412225DUF1700 domain-containing protein
10EL082_RS05025EL082_RS05050Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS05025513-0.594671MFS transporter
EL082_RS05030512-0.695557leucine--tRNA ligase
EL082_RS05035412-0.673999rhodanese-like domain-containing protein
EL082_RS05040511-1.016554DUF1542 domain-containing protein
EL082_RS05045612-1.071916DUF1542 domain-containing protein
EL082_RS05050412-0.294363NAD(P)/FAD-dependent oxidoreductase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05030TCRTETA575e-11 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 56.8 bits (137), Expect = 5e-11
Identities = 59/324 (18%), Positives = 129/324 (39%), Gaps = 18/324 (5%)

Query: 44 GIVLLINSLGMVVGNLLGGVLFDKLGGYKTILIGTFTCLFSTTLLNLFHGWPWYAVWLVL 103
GI+L + +L + G L D+ G +L+ ++ +W++
Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLY 100

Query: 104 LGFGGGMIIPAIYAMAGAVW----PNGGR-QTFNAIYLAQNIGVALGAALGGFVAELSFN 158
+G I A A+AGA R + F + G+ G LGG + S +
Sbjct: 101 IGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPH 160

Query: 159 YIFIANLVMYVLFAIVAITQFNLEINAKVK--RQDNIDLNNQENISRFISLL--LVCVVF 214
F A + L + + + R++ ++ +R ++++ L+ V F
Sbjct: 161 APFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220

Query: 215 AICWIGYIQWETTIASFTQS-IHISMSQYSVLWTINGIMILIAQPLIRPIIILLKGNLKK 273
+ +G + F + H + + GI+ +AQ +I + G ++
Sbjct: 221 IMQLVGQVP-AALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGE-RR 278

Query: 274 QMFVGILIFMGSFLVTSFAHQFSMFVIGMVILTFGEMFVWPAVPTIANQLAPKGKVGQYQ 333
+ +G++ +++ +FA + M MV+L G + + PA+ + ++ + + GQ Q
Sbjct: 279 ALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM-PALQAMLSRQVDEERQGQLQ 337

Query: 334 GIVNSASTVGKALGPLFGGLLVDL 357
G + + +++ +GPL +
Sbjct: 338 GSLAALTSLTSIVGPLLFTAIYAA 361


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05045GPOSANCHOR360.001 Gram-positive coccus surface protein anchor signature.
		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

Length = 539

Score = 36.2 bits (83), Expect = 0.001
Identities = 37/265 (13%), Positives = 88/265 (33%), Gaps = 13/265 (4%)

Query: 1685 VEKLLNQALTQINQDKTTNQVNLTEQQGVKAINDVQVNVVKKNEARTAITNVEDNKSQLF 1744
V++ ++ + N K N + +K ND + + + + ++
Sbjct: 55 VQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASK 114

Query: 1745 NNNDEATTEEKDEAIQQLKTILQNALKALQSDQTNQQVDQTENQSIEDINNVKLNIVKKP 1804
EA + ++A++ +++ + + +E K
Sbjct: 115 IQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE----------KAL 164

Query: 1805 AAINAIDQASTKQDQEINLTNEATTEEKEIALQQLKAAVNQYTNEVSSAHTNQNVADVLS 1864
A + + + + A + + L+ A+N T + + T + L+
Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224

Query: 1865 KALKEIEQ-IMPNIEVKPAAIEALKQLSSQIKTQINETNEATLEEKDEAINQLEEALKNS 1923
++E+ + + A +K L ++ E +A LE+ E A
Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL--EARQAELEKALEGAMNFSTADSAK 282

Query: 1924 IDTVDQSLTNAEVAKAKLEWETLIK 1948
I T++ E KA LE ++ +
Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVL 307


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05050IGASERPTASE350.005 IgA-specific serine endopeptidase (S6) signature.
		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

Length = 1541

Score = 34.7 bits (79), Expect = 0.005
Identities = 35/211 (16%), Positives = 66/211 (31%), Gaps = 5/211 (2%)

Query: 76 PTTEQVSPQNTATQEQNQQQNDNQNAVETNNAPSIDQVATEVNSEANQPNAITDQPVNED 135
T + + N++ A AP+ TE +E ++ + T + +D
Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057

Query: 136 NQEQA--QTQANHEKAQETPKEKQDKEAPVDHNEGLNKQD---KPVATVENNQTPKKRNK 190
E + E Q E +E Q K ATVE + K +
Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETE 1117

Query: 191 RDVGDDQNGNNVAPNQNQPVNTQDEALENAKQGATNEINQKATEKNQVIENTTEATQEEK 250
+ + + V+P Q Q Q +A + T I + ++ N + A +
Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177

Query: 251 QLALNDVAHQQFNANNNINQANTTNDVTTAK 281
+ N N++ + T +
Sbjct: 1178 NVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208


11EL082_RS05435EL082_RS05460Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS05435417-0.98706550S ribosomal protein L35
EL082_RS05440315-1.06093150S ribosomal protein L20
EL082_RS05445213-1.462669NUDIX domain-containing protein
EL082_RS05450311-1.486778hypothetical protein
EL082_RS05455210-2.082571trigger factor
EL082_RS05460212-1.455961ATP-dependent Clp protease ATP-binding subunit
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05460INFPOTNTIATR300.020 Macrophage infectivity potentiator signature.
		>INFPOTNTIATR#Macrophage infectivity potentiator signature.

Length = 233

Score = 29.6 bits (66), Expect = 0.020
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 153 VVKKEDGAVEN-GDTVNIDFSGS-VDGEEFEGGQAEGYDLEVGSGSFIPGFEEQLEGMKT 210
++ GA DTV ++++G+ +DG F+ + G IPG+ E L+ M
Sbjct: 132 IIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPA 191

Query: 211 GEEKDVVV 218
G +V V
Sbjct: 192 GSTWEVFV 199


12EL082_RS05520EL082_RS05545Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS05520213-5.534347bifunctional folylpolyglutamate
EL082_RS05525417-6.125799prepilin peptidase
EL082_RS05530117-3.950869DNA repair protein RadC
EL082_RS05535318-5.059841hypothetical protein
EL082_RS05540015-4.321489hypothetical protein
EL082_RS05545-114-3.370626DUF4930 family protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05525PREPILNPTASE642e-14 Type IV prepilin cysteine protease (C20) family sig...
		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

signature.
Length = 290

Score = 64.4 bits (157), Expect = 2e-14
Identities = 43/203 (21%), Positives = 86/203 (42%), Gaps = 15/203 (7%)

Query: 32 RSQCDFCQSKLKYYDLIPIISFLILKGKSRCCKQSLNYSYLIGELLALLPILLVYYQL-I 90
RS C C + + IP++S+L L+G+ R C+ ++ Y + ELL L + V L
Sbjct: 71 RSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAP 130

Query: 91 NINPQLYLISFLFLLVMSINDIEDYSI-NLYFLIIFTTVLLFTTQIFLNT---------- 139
L+ L+ ++ D++ + + L + LLF +
Sbjct: 131 GWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMA 190

Query: 140 -FILTFIISHLFYIFMNHY-IGYGDILLFNILSLFLSMNFMFYLILFTFMIGGLITIIIK 197
+++ + + F + +GYGD L L +L + ++L + ++G + I +
Sbjct: 191 GYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLI 250

Query: 198 TFFNHNI-KYIPLIPFIFLSFIF 219
NH+ K IP P++ ++
Sbjct: 251 LLRNHHQSKPIPFGPYLAIAGWI 273


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS0554560KDINNERMP280.017 60kDa inner membrane protein signature.
		>60KDINNERMP#60kDa inner membrane protein signature.

Length = 548

Score = 28.0 bits (62), Expect = 0.017
Identities = 10/31 (32%), Positives = 15/31 (48%)

Query: 19 IIIYIALKYAPFLRDQEWNPISNPPNQTEQN 49
++ IAL + F+ Q W NP Q +Q
Sbjct: 6 NLLVIALLFVSFMIWQAWEQDKNPQPQAQQT 36


13EL082_RS06010EL082_RS06060Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS06010213-2.895389penicillin-binding protein 2
EL082_RS06015112-2.56630450S ribosomal protein L33
EL082_RS06020118-3.3869535-formyltetrahydrofolate cyclo-ligase
EL082_RS06025216-3.251823rhomboid family intramembrane serine protease
EL082_RS06030012-2.998697DUF910 family protein
EL082_RS06035-214-2.789166ROK family glucokinase
EL082_RS06045-117-4.788778MTH1187 family thiamine-binding protein
EL082_RS06050020-5.184830MBL fold metallo-hydrolase
EL082_RS06055116-4.696509type II secretion system F family protein
EL082_RS06060113-3.830246prepilin-type N-terminal cleavage/methylation
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06030TCRTETA290.046 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 29.0 bits (65), Expect = 0.046
Identities = 21/115 (18%), Positives = 40/115 (34%), Gaps = 30/115 (26%)

Query: 247 FAGIFGNFVSLSFNTTTISVGASGAIFGLIGSIFAILY---LSKTFDKR----------V 293
A ++ F F+ ++G S A FG++ S+ + ++ +R
Sbjct: 229 PAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADG 288

Query: 294 IGQLLIA-----------LVILIGLSLFMSNINVM------AHLGGFIGGLLITL 331
G +L+A +V+L + M + M G + G L L
Sbjct: 289 TGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAAL 343


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06040PF03309280.045 Bvg accessory factor
		>PF03309#Bvg accessory factor

Length = 271

Score = 28.2 bits (63), Expect = 0.045
Identities = 11/46 (23%), Positives = 22/46 (47%), Gaps = 6/46 (13%)

Query: 5 ILAADIGGTTCKLGIFNTNLDR---IEKWSIHTD---TTDHTGKLL 44
+LA D+ T +G+ + + D +++W I T+ T D +
Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTI 47


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06060BCTERIALGSPF762e-17 Bacterial general secretion pathway protein F signa...
		>BCTERIALGSPF#Bacterial general secretion pathway protein F

signature.
Length = 408

Score = 76.0 bits (187), Expect = 2e-17
Identities = 49/265 (18%), Positives = 111/265 (41%), Gaps = 1/265 (0%)

Query: 92 ERFGNLEATLHESILFLKKQIQVKQSVIKTIQYPVVLMIIFFLILMLLNFTVIPQFKELY 151
E G+L+A L+ + +++ Q++ + + + YP VL ++ ++ +L V+P+ E +
Sbjct: 143 ETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQF 202

Query: 152 QSMNIALSPLQLVLSSFISGLPFFILFLTCIILVIVILIHTSYRNMPTIKQIH-LMSNLP 210
M AL VL + F ++ +L + R H + +LP
Sbjct: 203 IHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLP 262

Query: 211 IIKSYYKIFKTYQLSNELAHFYRNGINLQLIVEIFQQSNSNQFHQYLGDIILKQSNQGEK 270
+I + T + + L+ + + L + I SN + ++ + +G
Sbjct: 263 LIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVS 322

Query: 271 LPNILKQFKCYESDLIKFIEQGEKSGKLDIELTLYSQILVHQFEILAKRHIKFIQPIIFL 330
L L+Q + + I GE+SG+LD L + +F + +P++ +
Sbjct: 323 LHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDREFSSQMTLALGLFEPLLVV 382

Query: 331 MLGIFIVTLYLSIMLPMFDMLQSIN 355
+ ++ + L+I+ P+ + ++
Sbjct: 383 SMAAVVLFIVLAILQPILQLNTLMS 407


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06065BCTERIALGSPG506e-11 Bacterial general secretion pathway protein G signa...
		>BCTERIALGSPG#Bacterial general secretion pathway protein G

signature.
Length = 145

Score = 49.5 bits (118), Expect = 6e-11
Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 9 KTKAFTLIEMLLVLLIISLLLILIIPNV--AKQTAHIQSTGCDAQVKMINSQIEAYTLKH 66
K + FTL+E+++V++II +L L++PN+ K+ A Q + + + + ++ Y L +
Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA--VSDIVALENALDMYKLDN 63

Query: 67 NRNPNTIQDL 76
+ P T Q L
Sbjct: 64 HHYPTTNQGL 73


14EL082_RS06445EL082_RS06570Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS06445211-1.357062biotin--[acetyl-CoA-carboxylase] ligase
EL082_RS06450210-1.749069DEAD/DEAH box helicase family protein
EL082_RS06455-18-0.573870asparagine--tRNA ligase
EL082_RS064600130.692696DnaD domain-containing protein
EL082_RS06465115-0.135386endonuclease III
EL082_RS06470015-0.073445hypothetical protein
EL082_RS06475116-0.611755penicillin-binding protein
EL082_RS064800140.646727Holliday junction resolvase RecU
EL082_RS06485110-0.505282DUF1798 family protein
EL082_RS06490210-1.593431DUF1273 domain-containing protein
EL082_RS0649519-1.035009cell division regulator GpsB
EL082_RS065106460.671837class I SAM-dependent RNA methyltransferase
EL082_RS065156460.545626SDR family oxidoreductase
EL082_RS065206470.510009dynamin family protein
EL082_RS065257520.8502825'-3' exonuclease
EL082_RS065307510.865551ribonuclease HI family protein
EL082_RS06535-1110.579938queuosine precursor transporter
EL082_RS065400110.341294zinc-finger domain-containing protein
EL082_RS065450110.485274NifU N-terminal domain-containing protein
EL082_RS06550-1110.125184conserved virulence factor C family protein
EL082_RS06555-1110.363126BrxA/BrxB family bacilliredoxin
EL082_RS06560112-0.175869thymidylate synthase
EL082_RS06565312-0.762706dihydrofolate reductase
EL082_RS06570312-1.025906DegV family protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06485MICOLLPTASE290.012 Microbial collagenase metalloprotease (M9) signature.
		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

Length = 1104

Score = 29.3 bits (65), Expect = 0.012
Identities = 20/106 (18%), Positives = 37/106 (34%), Gaps = 4/106 (3%)

Query: 16 DGRKSTSNSSSIEYGGRG-MSLEKDIEHSNAFYLKRGIAVIHKKPTPVQIVNVHYPKRSK 74
DG KS ++ +Y G ++ + +N + + PV+++N P
Sbjct: 814 DGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDF 873

Query: 75 AVINE---AYFRTPSTTDYNGVYNGYYIDFEAKETKNKTSFPLNNI 117
N+ + T + YY D K T LN++
Sbjct: 874 EKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSV 919


15EL082_RS07055EL082_RS07090Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS07055-212-3.573400thermonuclease family protein
EL082_RS07060-111-4.341802hypothetical protein
EL082_RS07065-112-4.014160hypothetical protein
EL082_RS07070118-4.473521response regulator transcription factor
EL082_RS07075218-5.503019sensor histidine kinase
EL082_RS11915114-4.561570ABC transporter permease
EL082_RS07080114-4.588107ABC transporter ATP-binding protein
EL082_RS07085011-3.716361cardiolipin synthase
EL082_RS07090012-3.237476hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07080HTHFIS568e-12 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 56.4 bits (136), Expect = 8e-12
Identities = 22/116 (18%), Positives = 44/116 (37%), Gaps = 2/116 (1%)

Query: 2 ITMIIAEDQHMLRKAMVQLIELNDDLKVIADVGNGNEALELIKTYEPDIAILDIEMPGMT 61
T+++A+D +R + Q + V N I + D+ + D+ MP
Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61

Query: 62 GIEILAESKALKLQTKIIVVTTFKRPGYFEKAVANDVDAYVLKERSIDELVNTIQK 117
++L K + ++V++ KA Y+ K + EL+ I +
Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07085ACRIFLAVINRP290.034 Acriflavin resistance protein family signature.
		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

Length = 1034

Score = 28.7 bits (64), Expect = 0.034
Identities = 13/63 (20%), Positives = 24/63 (38%), Gaps = 3/63 (4%)

Query: 4 LFYFFSAFAIPFMLKKGFKSKYFITFVIAIIVTLGIT--FIIINDATLPLSIYFVVIFLM 61
S + L ++S + I + ++V LGI + +YF+V L
Sbjct: 874 ALVAISFVVVFLCLAALYES-WSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLT 932

Query: 62 CVG 64
+G
Sbjct: 933 TIG 935


16EL082_RS07470EL082_RS07500Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS074702180.465788tRNA (guanosine(37)-N1)-methyltransferase TrmD
EL082_RS074751150.331192ribosome maturation factor RimM
EL082_RS07480411-0.32744030S ribosomal protein S16
EL082_RS07485511-0.187508signal recognition particle protein
EL082_RS07490511-0.214773putative DNA-binding protein
EL082_RS07495511-0.357363signal recognition particle-docking protein
EL082_RS07500312-0.054081chromosome segregation protein SMC
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07495BONTOXILYSIN270.021 Bontoxilysin signature.
		>BONTOXILYSIN#Bontoxilysin signature.

Length = 1196

Score = 26.8 bits (59), Expect = 0.021
Identities = 12/42 (28%), Positives = 23/42 (54%)

Query: 10 LRMNYLFDFYQSLLTDKQRNYLELFYLQDYALSEIADTFNVS 51
L +NY + S++ D+ N L+ FY + Y + D +N++
Sbjct: 334 LNLNYFCQSFNSIIPDRFSNALKHFYRKQYYTMDYTDNYNIN 375


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07505GPOSANCHOR499e-08 Gram-positive coccus surface protein anchor signature.
		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

Length = 539

Score = 48.9 bits (116), Expect = 9e-08
Identities = 40/316 (12%), Positives = 118/316 (37%), Gaps = 6/316 (1%)

Query: 156 IDRRQIIEESAGVLKYKKRKAESVQKLDQTEDNLSRVEDILYDLEGRVEPLKEEAAIAKE 215
+ + + E+++ + + + RKA+ + L+ + + + LE L A ++
Sbjct: 103 KNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 162

Query: 216 YKQLSSEMKKSDVIVTV---HDIDQYTQDNGQLDEQLNDLKSKQANKEAEQSQINQLLQK 272
+ + +D + +L++ L + A+ +
Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222

Query: 273 YKGQRQELDQNIEQLNYHLVKATEEFEKYSGQLNVLEERKKNQSETNARFEEEQDNLMSQ 332
++ +L++ +E + + + + LE R+ + ++
Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 282

Query: 333 LDNLKSEKDQAIQTLDQLKQKQKELNKTIQALESKLYVSDE---QHDEKLEEIKNKYYTL 389
+ L++EK L+ + + LN Q+L L S E Q + + ++++ +
Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 342

Query: 390 MSEQSDVNNDIRFLEHTINENEAKKSRLDSRLVEAFNQLKDIQNNISNTDKEYQQVQKDM 449
+ + + D+ + EA+ +L+ + + + ++ ++ + + +QV+K +
Sbjct: 343 EASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKAL 402

Query: 450 HNTEQQIKNIEKQLTE 465
++ +EK E
Sbjct: 403 EEANSKLAALEKLNKE 418



Score = 34.7 bits (79), Expect = 0.003
Identities = 26/192 (13%), Positives = 65/192 (33%), Gaps = 15/192 (7%)

Query: 675 TQKDELTTMRHQLK----DYQKQTHEFEKQFQTHQAQSEKLSETYFELSQSYNNLKEKAH 730
+K L + L+ + + +T +A+ L EL ++ +
Sbjct: 148 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 207

Query: 731 GYELELDRLKKQETHLKDEHEEFEFEKNDGY-QSDKSKATLEQKQHHLSEIQAQLKHLEE 789
++ L+ ++ L + E S A ++ + + ++A+ LE+
Sbjct: 208 ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 267

Query: 790 DIEKYTKLSKEGKETTTQTQQQLHQKQSDLAVVKERIKGQQQEIERLD----------KQ 839
+E S + + +++ A ++ + + + L KQ
Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQ 327

Query: 840 LESTEQQLDTVK 851
LE+ Q+L+
Sbjct: 328 LEAEHQKLEEQN 339


17EL082_RS07795EL082_RS07840Y        NYGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS07795235-0.993716N-acetyltransferase
EL082_RS078007410.272672noncanonical pyrimidine nucleotidase, YjjG
EL082_RS078058501.544909beta-class phenol-soluble modulin
EL082_RS078105380.734752beta-class phenol-soluble modulin
EL082_RS078153260.815246beta-class phenol-soluble modulin
EL082_RS07820620-0.497255beta-class phenol-soluble modulin
EL082_RS078253180.549341beta-class phenol-soluble modulin
EL082_RS078353170.180195*helix-turn-helix transcriptional regulator
EL082_RS078402160.234295hypothetical protein
18EL082_RS07900EL082_RS11935Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS079002103.254414hypothetical protein
EL082_RS079050172.018544phage tail protein
EL082_RS079101161.580401hypothetical protein
EL082_RS079152161.557020hypothetical protein
EL082_RS079202201.882965hypothetical protein
EL082_RS079252192.402443hypothetical protein
EL082_RS079300151.289212hypothetical protein
EL082_RS07935-1141.118375phage major capsid protein
EL082_RS119250151.567562Clp protease ClpP
EL082_RS07940-1151.506729phage portal protein
EL082_RS07945-1151.035869terminase large subunit
EL082_RS079500180.558685hypothetical protein
EL082_RS079552180.899154HNH endonuclease
EL082_RS079606241.006482hypothetical protein
EL082_RS079658280.252787helix-turn-helix transcriptional regulator
EL082_RS079709351.555049DUF1514 family protein
EL082_RS079757330.837965transcriptional regulator
EL082_RS079807311.318698DUF1381 domain-containing protein
EL082_RS079856291.568272hypothetical protein
EL082_RS079907311.101064hypothetical protein
EL082_RS080005320.846425DUF1024 family protein
EL082_RS08005430-0.553753hypothetical protein
EL082_RS080102340.658473hypothetical protein
EL082_RS080155300.475907hypothetical protein
EL082_RS080205300.378005thermonuclease family protein
EL082_RS080305300.703285hypothetical protein
EL082_RS080355270.893604hypothetical protein
EL082_RS080455301.471560hypothetical protein
EL082_RS080506291.539551hypothetical protein
EL082_RS080554261.574006DUF1064 domain-containing protein
EL082_RS119304271.953346DUF3269 family protein
EL082_RS080605251.466630hypothetical protein
EL082_RS080654282.523808AAA family ATPase
EL082_RS080754252.267579hypothetical protein
EL082_RS080804252.388850phage replisome organizer N-terminal
EL082_RS080903272.697231hypothetical protein
EL082_RS080953260.979184single-stranded DNA-binding protein
EL082_RS081003270.391788ERF family protein
EL082_RS08105531-1.747328DUF2483 family protein
EL082_RS08110428-2.272653hypothetical protein
EL082_RS08115525-2.849812DUF1270 family protein
EL082_RS08120724-1.927528hypothetical protein
EL082_RS08125723-2.679470DUF771 domain-containing protein
EL082_RS08130623-3.292110hypothetical protein
EL082_RS08135722-2.724756hypothetical protein
EL082_RS08140518-2.431459hypothetical protein
EL082_RS08145516-2.068365phage antirepressor KilAC domain-containing
EL082_RS08150315-3.541083DUF2513 domain-containing protein
EL082_RS11935016-3.167465hypothetical protein
19EL082_RS09305EL082_RS09440Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS09305-220-3.244842histidine phosphatase family protein
EL082_RS09310-120-2.624849hypothetical protein
EL082_RS09315019-3.392433sterile alpha motif-like domain-containing
EL082_RS09320017-3.071432hypothetical protein
EL082_RS09325117-3.053531hypothetical protein
EL082_RS09330219-2.443726hypothetical protein
EL082_RS09335218-2.561968hypothetical protein
EL082_RS09340515-2.897698poly-gamma-glutamate hydrolase family protein
EL082_RS09345616-2.375410hypothetical protein
EL082_RS09350614-3.855785hypothetical protein
EL082_RS09355016-3.500430hypothetical protein
EL082_RS09360012-1.968599hypothetical protein
EL082_RS09365010-1.631951cold-shock protein
EL082_RS09370113-1.144910hypothetical protein
EL082_RS09375016-1.474553cation transporter
EL082_RS09380-116-1.430684DUF4352 domain-containing protein
EL082_RS09385017-1.257226hypothetical protein
EL082_RS09390122-2.738114aldo/keto reductase
EL082_RS09395523-4.146723TetR/AcrR family transcriptional regulator
EL082_RS09400823-6.443642hypothetical protein
EL082_RS09410025-8.647067hypothetical protein
EL082_RS09415224-8.917965hypothetical protein
EL082_RS09420122-7.232950hypothetical protein
EL082_RS09425221-6.832417hypothetical protein
EL082_RS09430525-7.096009hypothetical protein
EL082_RS09435523-5.964118hypothetical protein
EL082_RS09440618-4.048503hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS09360TYPE3IMSPROT270.004 Type III secretion system inner membrane S protein ...
		>TYPE3IMSPROT#Type III secretion system inner membrane S protein

family signature.
Length = 354

Score = 27.4 bits (61), Expect = 0.004
Identities = 8/19 (42%), Positives = 13/19 (68%)

Query: 47 TVKKVKDSAKKKDNPKSQD 65
T KK++D+ KK KS++
Sbjct: 10 TPKKIRDARKKGQVAKSKE 28


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS09390VACCYTOTOXIN290.010 Helicobacter pylori vacuolating cytotoxin signature.
		>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature.

Length = 1291

Score = 28.8 bits (64), Expect = 0.010
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 6/59 (10%)

Query: 81 AKKQSSSQSKPKHNKQSSTQNNGQNAQQGSQSQQSNGQ------NQQQSQYQQPQQSNG 133
A + + KP ++TQNN +N +Q S SN Q + Q+++ Q Q +G
Sbjct: 325 APPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQKTEIQPTQVIDG 383



Score = 28.5 bits (63), Expect = 0.016
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)

Query: 76 KKKDKAKKQSSSQSKPKHNKQSSTQNNGQNAQQGSQSQQSNGQNQQQSQYQQPQQ 130
K K K +++Q+ K++KQ S+QNN S +Q N N Q QP Q
Sbjct: 332 KDKPNDKPSNTTQNNAKNDKQESSQNN-------SNTQVINPPNSAQKTEIQPTQ 379


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS09400HTHTETR351e-04 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 35.0 bits (80), Expect = 1e-04
Identities = 16/116 (13%), Positives = 35/116 (30%), Gaps = 10/116 (8%)

Query: 21 AKILFWTLKTKPLEKITINELCEKANYPRATFYNYFDDINDLLNYC-------WQRIASD 73
A LF + + ++ E+ + A R Y +F D +DL + + +
Sbjct: 20 ALRLF---SQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76

Query: 74 MVVDNYDSLTPEKRPYILFERCYDYLNGYRDNIAKIMTHNTNDGRFAESLRKYIRQ 129
R ++ R + +I+ H +++ R
Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132


20EL082_RS09485EL082_RS09510Y        NNGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS094853402.500471phosphopyruvate hydratase
EL082_RS094902372.8328962,3-bisphosphoglycerate-independent
EL082_RS094952302.372756triose-phosphate isomerase
EL082_RS095004252.466515phosphoglycerate kinase
EL082_RS095052211.818296type I glyceraldehyde-3-phosphate dehydrogenase
EL082_RS095103141.573476transcriptional regulator
21EL082_RS09970EL082_RS10030Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS09970213-0.893047TIGR00730 family Rossman fold protein
EL082_RS11945316-2.010144hypothetical protein
EL082_RS09975416-1.929298MBL fold metallo-hydrolase
EL082_RS09980218-2.419185Rrf2 family transcriptional regulator
EL082_RS09985-115-2.653425NAD(P)H-binding protein
EL082_RS09990-116-2.619171GNAT family N-acetyltransferase
EL082_RS09995113-2.756665hypothetical protein
EL082_RS10000013-2.568019hypothetical protein
EL082_RS10005214-2.815999GNAT family N-acetyltransferase
EL082_RS10010213-2.747262DUF1129 family protein
EL082_RS10015013-1.584578DUF456 domain-containing protein
EL082_RS10020-114-2.173340MFS transporter
EL082_RS10025013-3.766100LysR family transcriptional regulator
EL082_RS10030012-4.000686DUF402 domain-containing protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS09985NUCEPIMERASE270.048 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 27.1 bits (60), Expect = 0.048
Identities = 13/82 (15%), Positives = 32/82 (39%), Gaps = 10/82 (12%)

Query: 1 MKAIILGGNGLVGRELTRQWLKRDQDI-------EIYVVS--RSGNNVISHKNVHNIKGD 51
MK ++ G G +G ++++ L+ + + Y VS ++ +++ K D
Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60

Query: 52 IQHVEQIKSQLPN-QVDYVVDL 72
+ E + + + V
Sbjct: 61 LADREGMTDLFASGHFERVFIS 82


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10000BACINVASINB270.024 Salmonella/Shigella invasin protein B signature.
		>BACINVASINB#Salmonella/Shigella invasin protein B signature.

Length = 593

Score = 27.4 bits (60), Expect = 0.024
Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 5/132 (3%)

Query: 16 SACGKSEEKASL-EKSVDKLEKENKSLKAQKKKLTKQKDDLKDQQDKLQKEVDSTASSEA 74
+A G+++E L E S+ K + A KKLT+ ++ L+ L A +EA
Sbjct: 131 TALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQS----LDPADPGYAQAEA 186

Query: 75 SSTDSNDKDSEKQSNEDKSSSKSSLQQNDQQSTEEKDASKQTQNQSSTTTQSKNNPNQTS 134
+ + + +E + DK++ + D ++ EK + T+ Q + S+N +Q
Sbjct: 187 AVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGE 246

Query: 135 QQNSNNKASTNQ 146
Q N +N A
Sbjct: 247 QDNLSNVARLTM 258


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10005SACTRNSFRASE290.005 Streptothricin acetyltransferase signature.
		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

Length = 173

Score = 28.8 bits (64), Expect = 0.005
Identities = 15/100 (15%), Positives = 34/100 (34%), Gaps = 12/100 (12%)

Query: 48 LRHTNDTILLLEHNQEIKGFIWGHYELQ------------TKTVIIELLYVYPDYRRQGL 95
+ D + + + +E + +Y +IE + V DYR++G+
Sbjct: 47 FKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGV 106

Query: 96 AKQLKMAIEQWAKDIGAVSIQSTIHIKNEAMLNLNRQLGY 135
L +WAK+ + N + + + +
Sbjct: 107 GTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10020TCRTETA513e-09 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 51.4 bits (123), Expect = 3e-09
Identities = 64/336 (19%), Positives = 129/336 (38%), Gaps = 23/336 (6%)

Query: 11 KNYKLFV--VNMLLLGMGIAVTVPYLVLFATKDLGMTTKQ---YGLLLALAAISQFTVNS 65
N L V + L +GI + +P L +DL + YG+LLAL A+ QF
Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLP-GLLRDLVHSNDVTAHYGILLALYALMQFACAP 61

Query: 66 IIARFSDTHNINRKFLIITALFMGAISFSIYFFVKDILLFIILYALFQGLFAPAMPQLYA 125
++ SD R+ +++ +L A+ ++I L + + + G+ A
Sbjct: 62 VLGALSD--RFGRRPVLLVSLAGAAVDYAI-MATAPFLWVLYIGRIVAGITGATGAVAGA 118

Query: 126 SARESINVSSSRENAKFANTVLRSMFSLGFLFGPFIGSQLIELNGYSGL-FGGTVSIILF 184
+ + + F + + F G + GP +G + + ++ ++ + F
Sbjct: 119 YIADITDGDERARHFGF----MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174

Query: 185 TLILQVFFYQNLNVKQPISQQQHVEKVAPNMFKDKTLLIPFLA--FILLHIGQWMYTMNM 242
+ + ++P+ ++ + + T++ +A FI+ +GQ +
Sbjct: 175 LTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL-W 233

Query: 243 PLFVTDYLHEKEGHVGYLASLCAGLEVPF-MVILGILSRKLPTRTLLIYGGIFGGAFYFS 301
+F D H +G + L +I G ++ +L R L+ G I G Y
Sbjct: 234 VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYIL 293

Query: 302 ISLFKNFYMMLLGQLFLAFFLAILLGIGISYFQDIL 337
++ +M + LA GIG+ Q +L
Sbjct: 294 LAFATRGWMAFPIMVLLASG-----GIGMPALQAML 324



Score = 40.6 bits (95), Expect = 8e-06
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 8/157 (5%)

Query: 215 MFKDKTLLIPFLAFILLHIGQWMYTMNMPLFVTDYLHEKE--GHVGYLASLCAGLEVPFM 272
M ++ L++ L +G + +P + D +H + H G L +L A ++
Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60

Query: 273 VILGILSRKLPTRTLLIYGGIFGGAFYFSISLFKNFYMMLLGQLFLAFFLAILLGIGISY 332
+LG LS + R +L+ Y ++ +++ +G++ A G +Y
Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AY 119

Query: 333 FQDILPD-----FPGYASTLFANAMVIGQLCGNLLGG 364
DI G+ S F MV G + G L+GG
Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG 156


22EL082_RS10275EL082_RS10340Y        Y        YPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS10275217-2.037081tyrosine-type recombinase/integrase
EL082_RS10280216-1.957434hypothetical protein
EL082_RS10285113-2.645073DUF2922 domain-containing protein
EL082_RS10290012-2.522073DMT family transporter
EL082_RS10295111-2.906260hypothetical protein
EL082_RS10300014-2.738728winged helix DNA-binding protein
EL082_RS10305215-1.513819alpha/beta hydrolase
EL082_RS10310015-1.202649hypothetical protein
EL082_RS10315114-0.094436hypothetical protein
EL082_RS10320215-0.075333alpha/beta hydrolase
EL082_RS10325315-0.350543HAD family hydrolase
EL082_RS103302130.071815iron ABC transporter permease
EL082_RS10335112-0.278090ABC transporter substrate-binding protein
EL082_RS10340213-0.357540MATE family efflux transporter
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10305CHANLCOLICIN290.017 Channel forming colicin signature.
		>CHANLCOLICIN#Channel forming colicin signature.

Length = 522

Score = 29.3 bits (65), Expect = 0.017
Identities = 22/135 (16%), Positives = 44/135 (32%), Gaps = 17/135 (12%)

Query: 36 FKQLSQQLSDRYRVITYDVRGHGKSSRCEAFD--------LEDHIEDLYILMERLNISSA 87
++ L+++ ++Y + ++ K + + +D + + +R I +A
Sbjct: 356 YQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIFNA 415

Query: 88 --HILGHDMG---GLIGKRFTEKYPFKTISLTAVASKREDI--THGFTKLMVEHQDLVAG 140
+ D K K V S I T + L + + A
Sbjct: 416 LASVKYDDWAKHLDQFAKYL--KITGHVSFGYDVVSDILKIKDTGDWKPLFLTLEKKAAD 473

Query: 141 FNKSEAVLLLFPILF 155
S V LLF +L
Sbjct: 474 AGVSYVVALLFSLLA 488


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10335FERRIBNDNGPP442e-07 Ferrichrome-binding periplasmic protein signature.
		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

Length = 296

Score = 44.2 bits (104), Expect = 2e-07
Identities = 36/204 (17%), Positives = 74/204 (36%), Gaps = 17/204 (8%)

Query: 30 GSKNQSNTGKTPYHRIVSLMPSNTEILYELGLGNRIVGVSTVDDY---------PKSVKK 80
N ++ +RIV+L E+L L LG GV+ +Y P SV
Sbjct: 23 WQMNTAHAAAIDPNRIVALEWLPVELL--LALGIVPYGVADTINYRLWVSEPPLPDSVID 80

Query: 81 GKKQFDAMNLNKEALLKAKPDLILAHESQKSSSGKVLDALKKEGVKVVYVKDAQSLKETY 140
+ + N E L + KP ++ S + G + Q L
Sbjct: 81 VGLRTEP---NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFN--FSDGKQPLAMAR 135

Query: 141 ETFKSIGKLTHREKQANQLVKETKDNVDKVVQSIPKHHKQPKVFMEVSSQPEIYTAGKHT 200
++ + L + + A + + +D + + K +P + + + G ++
Sbjct: 136 KSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNS 195

Query: 201 FFDDMLKQLDAKNSFE-DIDGWKS 223
F ++L + N+++ + + W S
Sbjct: 196 LFQEILDEYGIPNAWQGETNFWGS 219


23EL082_RS11185EL082_RS11210Y        Y        NPathogenicity Island (biased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS111857265.553906LysM peptidoglycan-binding domain-containing
EL082_RS111907265.289144cold-shock protein
EL082_RS111957255.229796DUF1304 family protein
EL082_RS112006235.052090LPXTG cell wall anchor domain-containing
EL082_RS112056245.155152hypothetical protein
EL082_RS112105193.830112hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11205INTIMIN512e-08 Intimin signature.
		>INTIMIN#Intimin signature.

Length = 939

Score = 50.8 bits (121), Expect = 2e-08
Identities = 76/413 (18%), Positives = 127/413 (30%), Gaps = 40/413 (9%)

Query: 36 TLPVTATDKDGNESQPSTTVVTDTTAPTVPSVNPVTSDDKTITGKAEPGSTVTVTFPDGT 95
+ A D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 96 KASGTTDADGNYVINIPANEDLKGGETLPVTSTDKDGNESEPATTVVTDTTAPSVPTVNP 155
K +G A+ NI + G L S + +G+ TV + P V+
Sbjct: 585 KKNGVAQANVPVSFNI-----VSGTAVLSANSANTNGSGK---ATVTLKSDKPGQVVVSA 636

Query: 156 VTSDDTQITGKAEPGSTVTVTFPDGTKATGKTDADGNYVINIPANED-LKGGETLPVTAT 214
T++ T + V F D TKA+ + I A++ +T T
Sbjct: 637 KTAEMTS------ALNANAVIFVDQTKAS---------ITEIKADKTTAVANGQDAITYT 681

Query: 215 DKDGNESQPST-TVVTDTTAPSVPTVNPVTSD-----DTQITGKAEPGSTVTVTFPDGT- 267
K +P + VT TT + + +D +T S V+ D
Sbjct: 682 VKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAV 741

Query: 268 --KATGTTDADGNYVIDIPANEDLKG-GETLPVTSTDKDGNTSEPASTVVTDTTAPSVPT 324
KA + D G LP + + T + P
Sbjct: 742 DVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPA 801

Query: 325 VNPVTSDDTQITGKAEPGSTVTVTFPDGTKASGTTDADGNYVIDIPSNEDLKGG--ETLP 382
+ V + Q+T K + +T++V D A+ T + ++ S T
Sbjct: 802 IASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCK 861

Query: 383 VTSTDKDGNQSEPAKTVVTDTTAPSVP---TINPVTSEDTQITGKAEPGSTVT 432
+Q+E A + + S Q A+ G T
Sbjct: 862 NFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914



Score = 49.7 bits (118), Expect = 4e-08
Identities = 62/352 (17%), Positives = 111/352 (31%), Gaps = 51/352 (14%)

Query: 122 TLPVTSTDKDGNESEPATTVVTDTTAPSVPTVNPVTSDDTQITGKAEPGSTVTVTFPDGT 181
+ + D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 182 KATGKTDADGNYVINIPANEDLKGGETLPVTATDKDGNESQPSTTVVTDTTAPSVPTVNP 241
K G A+ NI + + + T+ G + + S T
Sbjct: 585 KKNGVAQANVPVSFNIVSGTAVLSANS---ANTNGSGKATVTLKSDKPGQVVVSAKTAEM 641

Query: 242 VTSDDTQITGKAEPGSTVTVTFPDGTKATGTT--------DADGNYVIDIPANEDLKGGE 293
++ + V F D TKA+ T A+G I + +KG +
Sbjct: 642 TSALNAN-----------AVIFVDQTKASITEIKADKTTAVANGQDAITYTV-KVMKGDK 689

Query: 294 TLPVTSTDKDGNTSEPASTVVTDTTAPSVPTVNPVTSDD-------TQITGKAEPGSTVT 346
PV++ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 347 VTFPDGTKASGTTDADGNYVIDIPSNEDLKGGETLPVTSTDKDGNQSEPAKTVVTDTTAP 406
V F D + + + LP + + T
Sbjct: 748 VEFFTTLTI------DDGNIEIVGTGVK----GKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 407 SVPTINPVTSEDTQITGKAEPGSTVTVTFPDGTTATGKTDENGNYVIDIPSN 458
+ P I V + Q+T K + +T++V D TAT Y I P++
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTAT--------YTIATPNS 841



Score = 32.7 bits (74), Expect = 0.006
Identities = 58/346 (16%), Positives = 99/346 (28%), Gaps = 27/346 (7%)

Query: 28 NEDLKGGETLPVTATDKDGNESQPSTTVVTDTTAPT-VPSVNPVTSDDKTITGKAEPGST 86
+ G E + TAT K +Q + V + + T V S N ++
Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628

Query: 87 VTVTFPDGTKASGTTDADGNYVI----------NIPANED-LKGGETLPVTSTDKDGNES 135
A T+ + N VI I A++ +T T K
Sbjct: 629 PGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGD 688

Query: 136 EP-ATTVVTDTTAPSVPTVNPVTSD-----DTQITGKAEPGSTVTVTFPDGT---KATGK 186
+P + VT TT + + +D +T S V+ D KA
Sbjct: 689 KPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748

Query: 187 TDADGNYVINIPANEDLKG-GETLPVTATDKDGNESQPSTTVVTDTTAPSVPTVNPVTSD 245
+ + G LP + S T + P + V +
Sbjct: 749 EFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDAS 808

Query: 246 DTQITGKAEPGSTVTVTFPDGTKATGTTDADGNYVIDIPANEDLKGG--ETLPVTSTDKD 303
Q+T K + +T++V D AT T + ++ + T
Sbjct: 809 SGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLP 868

Query: 304 GNTSEPASTVVTDTTAPSVP---TVNPVTSDDTQITGKAEPGSTVT 346
+ +E + A + + S Q A+ G T
Sbjct: 869 SSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11210INTIMIN469e-07 Intimin signature.
		>INTIMIN#Intimin signature.

Length = 939

Score = 46.2 bits (109), Expect = 9e-07
Identities = 63/347 (18%), Positives = 109/347 (31%), Gaps = 43/347 (12%)

Query: 932 TLPVTATDKDGNKSEPATTVVTDTTAPTVPSVNPVTSDDTQITGKAEPGSTVTVTFPDGN 991
+ A D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 992 TASGTTDADGNYVINIPSGEDLKGGETLPVTATDKDGNKSEPATTVVTDTTAPTVPTVNP 1051
+G A+ NI SG T ++A + N S AT + P
Sbjct: 585 KKNGVAQANVPVSFNIVSG-------TAVLSANSANTNGSGKATVTLKSDK----PGQVV 633

Query: 1052 VTSDDKTITGKAEPGSTVTVTFPDGNTASGTT--------DEDGNYTITIPTNEDLKGGE 1103
V++ + V F D AS T +G IT T + +KG +
Sbjct: 634 VSAK---TAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK 689

Query: 1104 ALPVTSTDKAGNTSAPATTTVTDTTAPTAPSVNPVTSDD-------TQITGKAEPGSTVT 1156
PV++ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 1157 VTFPDGTKASGTTDADGNYVIDIPANEDLKGGETLPVTATDKAGNQSGETTTTVTDTTAP 1216
V F D + + LP + T
Sbjct: 748 VEFFTTLTI------DDGNIEIVGTGVK----GKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 1217 TAPSVNPVTSDDKTITGKAEPGSTVTVTFPDGTTTTGTADQDGNYVI 1263
P++ V + +T K + +T++V D T T T + ++
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 40.4 bits (94), Expect = 5e-05
Identities = 66/368 (17%), Positives = 118/368 (32%), Gaps = 28/368 (7%)

Query: 216 GTTQVTTADASGNYTVNIPA-NEDFTGGETIKASAKDAAGNKSVDSNVTVTDTTAPNQPT 274
G Q + + ++ +Y +PA + + + A A D GN S +NV +T T N
Sbjct: 497 GQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSS--NNVLLTITVLSNGQV 554

Query: 275 VNQVTSEDKTI-TGKAEPNSTVTVTFPDGTKVQAITATDGSYRVAVPTNIDLV-GGETLG 332
V+QV D T A+ + T +T+ A +G + VP + ++V G L
Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITY------TATVKKNGVAQANVPVSFNIVSGTAVLS 608

Query: 333 VTS--TDKAGNTSTAANTTVVDVTAPKEPVINDVTSEDKTITGTSEPNSTVTVTFPDGTK 390
S T+ +G + + ++ + + ++T K
Sbjct: 609 ANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV-DQTKASITEIKADK 667

Query: 391 ASATADASGNYTIGIPDSEDLKGDEELSVVATDAAGNVSVDAGTTVLDKTPPEVPTINPV 450
+A A+ T + + K V T G +S T + T
Sbjct: 668 TTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTP 727

Query: 451 TSEDKT--ITGKAEPNSTVTVTF-PDGTTANATTDGDGNYTIDIPANEDLRGGEALPVTS 507
+ ++ A V F T + + G LP
Sbjct: 728 GKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGV-----------KGKLPTVW 776

Query: 508 TDGAGNQSGAATTTVTDTTGPTVPTINPVTSEDTTITGHAEPGSTVTVTFPDGNTATGTT 567
A+ T P I V + +T + +T++V D TAT T
Sbjct: 777 LQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTI 836

Query: 568 DADGNYVI 575
+ ++
Sbjct: 837 ATPNSLIV 844



Score = 40.1 bits (93), Expect = 7e-05
Identities = 66/347 (19%), Positives = 116/347 (33%), Gaps = 45/347 (12%)

Query: 417 LSVVATDAAGNVSVDAGTTVLDKTPPEVPTINPVTSEDKTITGKAEPNSTVTVTFPDGTT 476
++ A D GN S + T+ + +V VT T A+ + T +T+
Sbjct: 527 VTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITY----- 580

Query: 477 ANATTDGDGNYTIDIPANEDLRGGEALPVTSTDGAGNQSGAATTTVTDTTGPTVPTINPV 536
AT +G ++P + ++ G A+ ++ N SG AT T+ V
Sbjct: 581 -TATVKKNGVAQANVPVSFNIVSGTAVL-SANSANTNGSGKATVTLKSDKPGQVVVSAKT 638

Query: 537 TSEDTTITGHAEPGSTVTVTFPDGNTATGTT--------DADGNYVINIPTDEDLKGGEE 588
+ + +A V F D A+ T A+G I T + +KG +
Sbjct: 639 AEMTSALNANA-------VIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK- 689

Query: 589 LPVTSTDKAGNKSDVATTEVTDTTSPEAPTVNPVTSED-------TTITGKAEPNSTVTV 641
PV++ + + + T+ T +TS ++ A V
Sbjct: 690 -PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748

Query: 642 TF-PDGTTATGNTDADGNYVIDIPSNEDLKGGETLPVTSTDKAGNTSQPASTVVTDTTAP 700
F T GN + G V LP + + T
Sbjct: 749 EFFTTLTIDDGNIEIVGTGV-----------KGKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 701 TVPSVNPVSSEDKTVTGKAEPGSTVTVTFPDGTTASGTTDADGNYTI 747
P++ V + VT K + +T++V D TA+ T + +
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 36.2 bits (83), Expect = 0.001
Identities = 54/336 (16%), Positives = 100/336 (29%), Gaps = 21/336 (6%)

Query: 330 TLGVTSTDKAGNTSTAANTTVVDVTAPKEPVINDVTSEDKTITGTSEPNS---TVTVTFP 386
+ + D+ GN+S T+ ++ + VT T + T T T
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVK 585

Query: 387 DGTKASATADASGNYTIGIPDSEDLKGDEELSVVATDAAGNVSVDAGTTVLDKTPPEVPT 446
A A S N G + T+ +G +V + + T
Sbjct: 586 KNGVAQANVPVSFNIVSGT-------AVLSANSANTNGSGKATVTLKSDKPGQVVVSAKT 638

Query: 447 INPVTSED-KTITGKAEPNSTVTVTFPDGTTANATTDGDGNYTIDIPANEDLRGGEALPV 505
++ + + + +++T D TTA A YT+ + + + +
Sbjct: 639 AEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTF 698

Query: 506 TSTDGAGNQSGAATTTVTDTTGPTVPTINPVTSEDTTITGHAEPGSTVTVTFPDGNTATG 565
T+T G + S T T T + ++ A V F T
Sbjct: 699 TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEF----FTTL 754

Query: 566 TTDADGNYVINIPTDEDLKGGEELPVTSTDKAGNKSDVATTEVTDTTSPEAPTVNPVTSE 625
T D ++ L P + T P + V +
Sbjct: 755 TIDDGNIEIVGTGVKGKL------PTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDAS 808

Query: 626 DTTITGKAEPNSTVTVTFPDGTTATGNTDADGNYVI 661
+T K + +T++V D TAT + ++
Sbjct: 809 SGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 35.0 bits (80), Expect = 0.002
Identities = 56/348 (16%), Positives = 110/348 (31%), Gaps = 45/348 (12%)

Query: 674 TLPVTSTDKAGNTSQPASTVVTDTTAPTVPSVNPVSSEDKTVTGKAEPGSTVTVTFPDGT 733
+ + D+ GN+S +T + V V+ T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 734 TASGTTDADGNYTIDIPANEDLKGGETLPVTATDKDGNKSEEATTTVSDKTAPEAPTVNP 793
+G A+ + +I + + + T+ G + + + A T
Sbjct: 585 KKNGVAQANVPVSFNIVSGTAVLSANS---ANTNGSGKATVTLKSDKPGQVVVSAKTAEM 641

Query: 794 VTSDDTQITGKAEPNSTVTVTFPDGHTASGTT--------DADGNYVINIPSSEDLKGGE 845
++ + V F D AS T A+G I + + +KG +
Sbjct: 642 TSALNAN-----------AVIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK 689

Query: 846 TLPVTATDKAGNTSEQASTVVTDTTAPTVPSVNPVTSDD-------TQITGKAEPGSTVT 898
PV+ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 899 VTF-PDGTTATGTTDADGNYTIDIPANEDLKGGETLPVTATDKDGNKSEPATTVVTDTTA 957
V F T G + G LP + + T
Sbjct: 748 VEFFTTLTIDDGNIEIVGTGV-----------KGKLPTVWLQYGQVNLKASGGNGKYTWR 796

Query: 958 PTVPSVNPVTSDDTQITGKAEPGSTVTVTFPDGNTASGTTDADGNYVI 1005
P++ V + Q+T K + +T++V D TA+ T + ++
Sbjct: 797 SANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 33.5 bits (76), Expect = 0.007
Identities = 56/344 (16%), Positives = 100/344 (29%), Gaps = 30/344 (8%)

Query: 56 NSDGTFTVTIPKSAAGQYTIAIDAPNYDNDETN-----TFNIVDNTIVPAPLVDPVDDND 110
NS +TI + GQ + ++ D+T+ T I V V +
Sbjct: 537 NSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPV 596

Query: 111 TTIGVHGTAGSTVTVKYSNNNVIGTVTLGANSTTGTLTLSK------PLAAGTQLTSTAT 164
+ V GTA + +N + TVTL ++ + +K L A + T
Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656

Query: 165 KNGKTSAVSPTVTVTDATAPDAPVINPVTSDDTTVTGKAEPNSTVTVTFPDGTTQVTTAD 224
K T + T A DA E T T+ +T+ T +
Sbjct: 657 KASITE-IKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTN 715

Query: 225 ASGNYTVNIPANEDFTGGETIKASAKDAAGNKSVDSNVTVTDTTAPNQPTVNQVTSEDKT 284
G V + T K+ + +VD + +
Sbjct: 716 --GYAKVTL------TSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTG 767

Query: 285 ITGKAEPNSTVTVTFPDGTKVQAITATDGSYR-VAVPTNIDLVGGETLGVTSTDKAGNTS 343
+ G TV G + +G Y + I V + VT +K T
Sbjct: 768 VKG-----KLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTI 822

Query: 344 TAANTTVVDVT----APKEPVINDVTSEDKTITGTSEPNSTVTV 383
+ ++ T P ++ +++ + +
Sbjct: 823 SVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGK 866


24EL082_RS11390EL082_RS11505Y        NYGenomic Island
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS11390-212-3.754178hypothetical protein
EL082_RS11395-113-2.847075histidine phosphatase family protein
EL082_RS11400316-3.480539LysE family translocator
EL082_RS11405217-4.399991hypothetical protein
EL082_RS11410314-4.206676GlsB/YeaQ/YmgE family stress response membrane
EL082_RS11955316-3.600183hypothetical protein
EL082_RS11415317-2.733325hypothetical protein
EL082_RS11420518-3.581500terminase small subunit
EL082_RS11425618-2.410759hypothetical protein
EL082_RS11435620-1.721230pathogenicity island protein
EL082_RS11440623-2.027769hypothetical protein
EL082_RS11445-120-1.367163hypothetical protein
EL082_RS11450-119-1.564084pathogenicity island protein
EL082_RS11460019-2.346387hypothetical protein
EL082_RS11465218-5.044741hypothetical protein
EL082_RS11470117-4.173060hypothetical protein
EL082_RS11475216-5.711041hypothetical protein
EL082_RS11480116-4.591976SAP domain-containing protein
EL082_RS11485316-4.041178site-specific integrase
EL082_RS11490316-2.87778030S ribosomal protein S18
EL082_RS114955220.543087single-stranded DNA-binding protein
EL082_RS115002231.67324130S ribosomal protein S6
EL082_RS115052201.120010lysozyme
25EL082_RS00205EL082_RS00240N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS00205-181.207508YSIRK-type signal peptide-containing protein
EL082_RS002103131.270329type II toxin-antitoxin system Phd/YefM family
EL082_RS002152141.520685Txe/YoeB family addiction module toxin
EL082_RS002202142.277420citrate transporter
EL082_RS002250110.709766NAD(P)H-dependent oxidoreductase
EL082_RS002300100.806465SDR family NAD(P)-dependent oxidoreductase
EL082_RS00235-1111.190523multidrug efflux MFS transporter
EL082_RS002400120.432435ArgE/DapE family deacylase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00205GPOSANCHOR402e-05 Gram-positive coccus surface protein anchor signature.
		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

Length = 539

Score = 40.4 bits (94), Expect = 2e-05
Identities = 26/241 (10%), Positives = 68/241 (28%), Gaps = 4/241 (1%)

Query: 2 KNRKNSYSIRKLSVGASSIIVA-SMLFVGAESAQAAETESQDQTTVQNVKETTESSNSNQ 60
N YS+RKL G +S+ VA ++L G + ++ +++ E ++ +
Sbjct: 4 NNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAVATRSQTDTLEKVQERADKFE 63

Query: 61 TQQQPSEPTKAKDSDTNNTNVERPESNSTQTSNQDTDKMQDTSTNQTNENSKHIIDKTND 120
+ + + S N + + + + SN ++ + + ++
Sbjct: 64 IENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKA 123

Query: 121 VSHETTKTNDTDQTSSQDNSEQSLEVDSNEAPASNDKSTPTKQEPTNSKQDIDETSK--P 178
+ + T+ + LE + A + N K
Sbjct: 124 DLEKALEGAMNFSTADSAKIKT-LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 182

Query: 179 NEDSKLVPSKSNITSKADKQEQSSKEPGEDNAQKDKHVSQEDSSIEKQGTQESPQTDSHK 238
E + L ++ + + S + + + +
Sbjct: 183 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 242

Query: 239 D 239

Sbjct: 243 A 243


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00230DHBDHDRGNASE793e-19 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 78.9 bits (194), Expect = 3e-19
Identities = 58/200 (29%), Positives = 97/200 (48%), Gaps = 6/200 (3%)

Query: 33 GKYALITGASSGLGEAFSKTFARHHFNLVLAARSEDKLNQLAHQLKAQYEINVIVIPADL 92
GK A ITGA+ G+GEA ++T A ++ + +KL ++ LKA+ + PAD+
Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66

Query: 93 SKTEDIYHLYDKLSEKGIEIEQLVNNAGYGKSGKLVDIGTEQLISNLKLNITSVTLLSRL 152
+ I + ++ + I+ LVN AG + G + + E+ + +N T V SR
Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

Query: 153 FGKDMVERNSGKILNVASLGAMTPDPYFNVYGPSRAYVMKLTETMYGELLDTNVNVSVLC 212
K M++R SG I+ V S A P Y S+A + T+ + EL + N+ +++
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186

Query: 213 PGPLDTN-----WAANAGKS 227
PG +T+ WA G
Sbjct: 187 PGSTETDMQWSLWADENGAE 206


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00235TCRTETB1392e-38 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 139 bits (351), Expect = 2e-38
Identities = 90/421 (21%), Positives = 178/421 (42%), Gaps = 16/421 (3%)

Query: 2 SSSEMTIAKRNTIVVVMLISAFVAMLNQTILNTALPAIISGLGIPETTAQWLITGFMLVN 61
+S + + N I++ + I +F ++LN+ +LN +LP I + P + W+ T FML
Sbjct: 3 TSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62

Query: 62 GVMIPLTAFLMDRYSTRGLYIFSMAAFLIGSLVAALSPN-FSILMVARVIQAIGAGILLP 120
+ + L D+ + L +F + GS++ + + FS+L++AR IQ GA
Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122

Query: 121 LMQFTVFTLFPVEKRGFAMGLTGIVAQSAPAIGPTLTGLLIDAFSWRMPFYVVATIAIIA 180
L+ V P E RG A GL G + +GP + G++ W + I
Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITV 182

Query: 181 FVIGYFFVENHSSPKDTALDKISVVYSTFGFGLILFAFSSISTLGITSPAVIITF-ILGV 239
+ + F I+ I + + + I+F I+ V
Sbjct: 183 PFLMKLLKKEVRIK------------GHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSV 230

Query: 240 IVIAIFTFRQLKIDHPLLNLRVFRSKTFTLSAVASMLLFIGIVGPALLIPMYVQTGLGLS 299
+ IF K+ P ++ + ++ F + + ++F + G ++P ++ LS
Sbjct: 231 LSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLS 290

Query: 300 -AVLSGLVILPGAVFNAFISVYTGKVFDRFGLRVLVIPGFTLLIIMTILHTFLSTDTPFW 358
A + ++I PG + G + DR G ++ G T L + + +FL T ++
Sbjct: 291 TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWF 350

Query: 359 YVVVIYAIRMFSVGLLIMPLNTAGLNALQSEEISHGTAIMNSLRIIAGAMGTAVSITILS 418
++I + + ++T ++L+ +E G +++N ++ G A+ +LS
Sbjct: 351 MTIIIVFVLGGLSFTKTV-ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409

Query: 419 I 419
I
Sbjct: 410 I 410


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00240SECA290.034 SecA protein signature.
		>SECA#SecA protein signature.

Length = 901

Score = 29.5 bits (66), Expect = 0.034
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%)

Query: 12 ILKDIVEIKT------VNDNEIEVARYLKDLLEKHGIKADIDEIKGHDNRANLIASIGEG 65
I++DI E V IE + + + L K GIK ++ K H N A ++A G
Sbjct: 438 IIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYP 497

Query: 66 HPVVAISGHM 75
V I+ +M
Sbjct: 498 AAVT-IATNM 506


26EL082_RS00380EL082_RS00425N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS003800170.855729DHA2 family efflux MFS transporter permease
EL082_RS00385-1140.254376arylamine N-acetyltransferase
EL082_RS003900151.226769TetR/AcrR family transcriptional regulator
EL082_RS003953162.157817ABC transporter permease
EL082_RS004003183.226913ABC transporter ATP-binding protein
EL082_RS004054213.640484TetR/AcrR family transcriptional regulator
EL082_RS004105214.512483histidine racemase CntK
EL082_RS004154224.561499staphylopine biosynthesis enzyme CntL
EL082_RS004203214.584493staphylopine biosynthesis dehydrogenase
EL082_RS004251214.594607nickel ABC transporter, nickel/metallophore
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00380TCRTETB1408e-39 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 140 bits (353), Expect = 8e-39
Identities = 97/420 (23%), Positives = 188/420 (44%), Gaps = 15/420 (3%)

Query: 4 TQPSHLNIKQRNLMIAVMMIGAFIGVLNQTLLTTILPEVMKDFAISSSTAQWLTTIFMLV 63
T S N++ ++I + ++ +F VLN+ +L LP++ DF ++ W+ T FML
Sbjct: 3 TSYSQSNLRHNQILIWLCIL-SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLT 61

Query: 64 NGIMIPVTAYLIERFSLRTLFFTAATCLILGSLICMLGVN-FPLLLVGRSIQALGAGILM 122
I V L ++ ++ L GS+I +G + F LL++ R IQ GA
Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121

Query: 123 PLSQTLLFIIFPVEKRGMAMGIFGLVIGFAPAIGPTAAGWFIHLFDWRYLFLVVLLISVV 182
L ++ P E RG A G+ G ++ +GP G H W YL L + +I+++
Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLL-IPMITII 180

Query: 183 DAIFGFLYLKNITETQQPSLDILSVIMSTLGFGGLLYGFSSAGNLGCSHPSVYVTIIISI 242
F LK + DI +I+ ++G + +S +I+S+
Sbjct: 181 TVPFLMKLLKKEVRIKGH-FDIKGIILMSVGIVFFMLFTTSY---------SISFLIVSV 230

Query: 243 IILALFIRRQLKLPSPLLEFRVFKYRSFTISMTLIVLMFVLFIGNLTILPIYMQTMMHWS 302
+ +F++ K+ P ++ + K F I + ++F G ++++P M+ + S
Sbjct: 231 LSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLS 290

Query: 303 PLESG-LILLPGGLVMGLLSPVTGKLYDRVGGRSLSITGMLLIMIGALFMAQFNPQTSAL 361
E G +I+ PG + + + + G L DR G + G+ + + L + F +T++
Sbjct: 291 TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-FLLETTSW 349

Query: 362 YVIVTFSILMLGNSMIMTPMTTQALNALPVSLIAHGTAMNNTIRQISAAIGTGILVTLMT 421
++ + ++ G S T ++T ++L G ++ N +S G I+ L++
Sbjct: 350 FMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00390HTHTETR559e-12 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 55.4 bits (133), Expect = 9e-12
Identities = 29/143 (20%), Positives = 52/143 (36%), Gaps = 10/143 (6%)

Query: 10 RKKRSDATHNKAIILQTTTQLLAQGEDISEMNMSEIAKKAGVGVGTLYRHFESKSLLCQA 69
RK + +A + IL +L +Q + +S ++ EIAK AGV G +Y HF+ KS L
Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQ-QGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61

Query: 70 MMDEKVHDMFDEMDTFLHQHQDASVRDKIYGILSIYLDLKEANFN---VLNFIEKSNSQH 126
+ + E++ + IL L+ ++ I
Sbjct: 62 IWEL-SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120

Query: 127 QSMINI-----LFYEQLKELIKD 144
M + + + I+
Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQ 143


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00395ABC2TRNSPORT565e-11 ABC-2 type transport system membrane protein signat...
		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

signature.
Length = 262

Score = 55.7 bits (134), Expect = 5e-11
Identities = 41/168 (24%), Positives = 71/168 (42%), Gaps = 3/168 (1%)

Query: 191 RERTTGTLERVLATPIRRSEIVFGYLLGYGIFAIIQTLIIVLFSIYLLNINLAGSLWYVL 250
R T E +L T +R +IV G + A + I + + L SL Y L
Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL-SLLYAL 151

Query: 251 LINILLAITALVMGIFISTFANSEFQMVQFIPIVAIPQVFFSG-IFPLENMTPWLANIGY 309
+ L + +G+ ++ A S + + +V P +F SG +FP++ +
Sbjct: 152 PVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAAR 211

Query: 310 LFPLRYAGDALTNIMIKGQGWSDIWFDVLILLIFIIIFIILNILGLKR 357
PL ++ D + IM+ D+ V L I+I+I L+ L+R
Sbjct: 212 FLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIPFFLSTALLRR 258


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00405HTHTETR453e-08 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 45.4 bits (107), Expect = 3e-08
Identities = 13/65 (20%), Positives = 31/65 (47%), Gaps = 4/65 (6%)

Query: 24 LLNVKSYDDISIKDICDESGISRGTFYQHYRDKDDFLFQYQKAMMKKGKRRLTQIQFEER 83
L + + S+ +I +G++RG Y H++DK D + + + + +++ E +
Sbjct: 23 LFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF----SEIWELSESNIGELELEYQ 78

Query: 84 RQFFE 88
+F
Sbjct: 79 AKFPG 83


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00425adhesinb330.002 Adhesin B signature.
		>adhesinb#Adhesin B signature.

Length = 310

Score = 32.9 bits (75), Expect = 0.002
Identities = 16/71 (22%), Positives = 28/71 (39%), Gaps = 8/71 (11%)

Query: 9 AVLLASGIILTGCGGNKGLEDKKEQKTLSYTTVKDIGDMNPHVYGGSMSAESMI------ 62
+LL + + L C K + K T I D+ ++ G ++ S++
Sbjct: 8 VLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDP 67

Query: 63 --YEPLVRNTK 71
YEPL + K
Sbjct: 68 HEYEPLPEDVK 78


27EL082_RS00945EL082_RS01025N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS00945-2110.687578MFS transporter
EL082_RS00950-2151.504358flavin reductase family protein
EL082_RS00955-2161.017220MFS transporter
EL082_RS009600181.250856TetR/AcrR family transcriptional regulator
EL082_RS009650110.818806TetR/AcrR family transcriptional regulator
EL082_RS009701100.994098hypothetical protein
EL082_RS00975180.807260MMPL family transporter
EL082_RS118800100.749752hypothetical protein
EL082_RS009800100.889702organic hydroperoxide resistance protein
EL082_RS009850100.975026cell wall anchor protein
EL082_RS00990-1100.816243amidase domain-containing protein
EL082_RS00995-1110.480023YhgE/Pip domain-containing protein
EL082_RS01000-110-0.021014(S)-acetoin forming diacetyl reductase
EL082_RS01005011-0.826270hypothetical protein
EL082_RS01010013-0.624301ArgE/DapE family deacylase
EL082_RS01015-114-1.535358hypothetical protein
EL082_RS01020-114-0.524440peptidoglycan DD-metalloendopeptidase family
EL082_RS01025-213-0.196062peptidase M4 family protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00945TCRTETA853e-20 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 84.9 bits (210), Expect = 3e-20
Identities = 73/366 (19%), Positives = 141/366 (38%), Gaps = 18/366 (4%)

Query: 10 ITTILFFSGIIVMGSLYTALPLTAAFAHSFHIPQSVATLNGV---IFSIMYSISCLFYGT 66
+ IL + +G + +P+ V G+ ++++M G
Sbjct: 7 LIVILSTVALDAVG-IGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65

Query: 67 ISDKYGRIKTILIGLSGLTIICFIIGFVQSFSLLLIMRAIQGIFAATFSPVAITYTTETY 126
+SD++GR +L+ L+G + I+ +L I R + GI AT VA Y +
Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADIT 124

Query: 127 PAKKRVTAISFISTSFMLSGVLGQNLSELI--VHHLNWHWVYFTLTVLYLCLIFVIYRYV 184
+R F+S F V G L L+ H +F L +
Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP---HAPFFAAAALNGLNFLTGCFLL 181

Query: 185 PESPRRNADVQLLKFFNNFKDFR--DNLKVLYCLFISFTLLIMFISMYAILNLYILSDKV 242
PES + + N FR + V+ L F ++ + + A L + D+
Sbjct: 182 PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241

Query: 243 NGDMSTASL-VKLFGVIGMLV-SLLGGRLSGRIGIKRVISLALLTSTLSLILMGITTNII 300
+ D +T + + FG++ L +++ G ++ R+G +R + L ++ IL+ T
Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301

Query: 301 CITLFSVTFVAGIAFAIPSVISKVGMTV-KHNQGFFLSVNTVILFMGTAIAPIL--MIYI 357
V +G +P++ + + V + QG + + + + P+L IY
Sbjct: 302 MAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360

Query: 358 AKLPQY 363
A + +
Sbjct: 361 ASITTW 366


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00955TCRTETA290.032 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 29.0 bits (65), Expect = 0.032
Identities = 15/121 (12%), Positives = 39/121 (32%), Gaps = 2/121 (1%)

Query: 249 IFGGISGHIIDQYGIQFAYFFGVILMSVASILLALTPIVWIVPFLSSLIFGVSYIFITGV 308
+ G + D++G + + +V ++A P +W++ ++ ++ G++
Sbjct: 58 ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVL-YIGRIVAGITGATGAVA 116

Query: 309 LLVWGVKIFVKNASLGIGIPFLMLAVGQVLGSMVAGPFIEDLGYTMTFIIYGLIGLVALL 368
+ G G V G ++ G + F + + L
Sbjct: 117 GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG-LMGGFSPHAPFFAAAALNGLNFL 175

Query: 369 L 369

Sbjct: 176 T 176


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00960HTHTETR622e-14 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 62.3 bits (151), Expect = 2e-14
Identities = 19/91 (20%), Positives = 33/91 (36%), Gaps = 3/91 (3%)

Query: 2 SKKKQDLLEVAERLFYEHGFRGVGLKQIIQEANVATMTLYNHFDSKEKLVEAVLQQREMR 61
+ +Q +L+VA RLF + G L +I + A V +Y HF K L + + E
Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69

Query: 62 YWQY---LEDGVHQSPQQPFIAAVDAHCKWL 89
+ + P + +
Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLEST 100


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00965HTHTETR462e-08 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 45.8 bits (108), Expect = 2e-08
Identities = 12/49 (24%), Positives = 22/49 (44%)

Query: 19 ELLNDYHFDEITVQKICDAAEINRSTFYRYFQDKYDLLYSLTEYMKEAL 67
L + ++ +I AA + R Y +F+DK DL + E + +
Sbjct: 22 RLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00975ACRIFLAVINRP681e-13 Acriflavin resistance protein family signature.
		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

Length = 1034

Score = 67.9 bits (166), Expect = 1e-13
Identities = 29/214 (13%), Positives = 76/214 (35%), Gaps = 20/214 (9%)

Query: 180 LVGIVTAFIILLITFGSLIAAGMPIVSALMGLGSSIGIIALLTNVFDIPNFTLTLAVMIG 239
I+ F+++ + ++ A +P ++ + L + I+A +++ M G
Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAF-------GYSINTLTMFG 397

Query: 240 LAVGI----DYSLFILFR-YKEIRKKGTPPVESIALAVGTAGSAVIFAGLTVMIAVCGLS 294
+ + I D ++ ++ + + + PP E+ ++ A++ + + ++
Sbjct: 398 MVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMA 457

Query: 295 LVGI---DFLAVMGFASAISVLFAVLAALTLLPALISVFHKRIKIKDKPEKSK-----DP 346
G ++ +VL AL L PAL + K + + K +
Sbjct: 458 FFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNT 517

Query: 347 KNHPWAKFVVGKPVLAIIISLIILIAAIIPISGM 380
+ + L+ + ++GM
Sbjct: 518 TFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGM 551



Score = 64.5 bits (157), Expect = 2e-12
Identities = 46/264 (17%), Positives = 92/264 (34%), Gaps = 40/264 (15%)

Query: 441 LKDIDNV-DTVEKPQL--NDNNHYA-LISIIPEDGPNAQSTSNLVYD-LRDYNKQAKEKY 495
LKD+ V E + N A + I G NA T+ + L + +
Sbjct: 262 LKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQ-- 319

Query: 496 DFNTEVTGQSVINIDMAEKLNNAIPVFAGVIILLAFVLLVFV--FRSILVPLKAV---LG 550
+ + ++ + I+L+ V+ +F+ R+ L+P AV L
Sbjct: 320 GMKVLYPYDTTPFVQ--LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLL 377

Query: 551 FVLSLMATLGFTTLVMQDGFLGGLFGVENTGPLLAFLPVITIGLLFGLAIDYELFLMTRV 610
+++A G++ + + G+ V+ IGLL +D + ++ V
Sbjct: 378 GTFAILAAFGYSINTLT---MFGM--------------VLAIGLL----VDDAIVVVENV 416

Query: 611 HEEYSKTGDND-HSIRVGIKESGPVIVAAALIMFSVFIAFVFQDDMQ---IKSMGISLAF 666
+ + + + +V A+++ +VFI F + I++
Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS 476

Query: 667 GVLFDAFVVRMTLIPALTKLFGKG 690
+ V + L PAL K
Sbjct: 477 AMALSVLVA-LILTPALCATLLKP 499



Score = 42.1 bits (99), Expect = 1e-05
Identities = 34/246 (13%), Positives = 75/246 (30%), Gaps = 37/246 (15%)

Query: 453 PQLNDNNHYALISIIPEDGPNAQSTSNLVYDLRDYNKQAKEK--YDFNTEVTGQSVINID 510
P+L N + I E P S D + K + TG S
Sbjct: 813 PRLERYNGLPSMEIQGEAAPGTSSG-----DAMALMENLASKLPAGIGYDWTGMS----Y 863

Query: 511 MAEKLNNAIPVFAGVIILLAFVLLVFVFRSILVPLKAVLGFVLSLMATLGFTTLVMQDGF 570
N P + ++ F+ L ++ S +P+ S+M +
Sbjct: 864 QERLSGNQAPALVAISFVVVFLCLAALYESWSIPV--------SVMLVVPLG-------I 908

Query: 571 LGGLFGVENTGPLLAFLPVITIGLLFGLAIDYELFLMTRVHEEYSKTGDNDHSIRVGIKE 630
+G L ++ + GL+ + ++ + K G +
Sbjct: 909 VGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG---KGVVEATLM 965

Query: 631 SG-----PVIVAAALIMFSVF-IAFVFQDDMQI-KSMGISLAFGVLFDAFVVRMTLIPAL 683
+ P+++ + + V +A ++GI + G + A ++ + +P
Sbjct: 966 AVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG-MVSATLLAIFFVPVF 1024

Query: 684 TKLFGK 689
+ +
Sbjct: 1025 FVVIRR 1030



Score = 38.7 bits (90), Expect = 1e-04
Identities = 34/164 (20%), Positives = 65/164 (39%), Gaps = 15/164 (9%)

Query: 180 LVGIVTAFIILLITFGSLIAAGMPIVSALMGLGSSIGIIALLTNVFDIPN---FTLTLAV 236
+ V F+ L + S ++ +G+ +G++ L +F+ N F + L
Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGI---VGVL-LAATLFNQKNDVYFMVGLLT 932

Query: 237 MIGLAV--GIDYSLFILFRYKEIRKKGTPPVESIALAVGTAGSAVIFAGLTVMIAVCGLS 294
IGL+ I L + F + K+G VE+ +AV ++ L ++ V L+
Sbjct: 933 TIGLSAKNAI---LIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989

Query: 295 L---VGIDFLAVMGFASAISVLFAVLAALTLLPALISVFHKRIK 335
+ G +G ++ A L A+ +P V + K
Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFK 1033


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00985IGASERPTASE398e-05 IgA-specific serine endopeptidase (S6) signature.
		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

Length = 1541

Score = 38.9 bits (90), Expect = 8e-05
Identities = 34/235 (14%), Positives = 81/235 (34%), Gaps = 16/235 (6%)

Query: 114 ETQHSTDSAEETPSEKNAENVKDKDDVTKDLDKILADLDLSSENVDNHQQKDGETSQAQE 173
++ + AE + E ++D + S N Q ++ +
Sbjct: 1033 PSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT-----NEVAQ 1087

Query: 174 QAQPHDKQQTLNHKQTSVLDDLDKIKQDTSLDEDADTTQKQKRSDSSSNQRQDRQQDSKN 233
+ QT K+T+ ++ +K K + + TQ+ + S + +Q++ + +
Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAK------VETEKTQEVPKVTSQVSPKQEQSETVQP 1141

Query: 234 QSQSNTRELPHSNAKEQQTLDDLKHIADEADVKQSDQKQDGHVGKITKELEGSDKINQAI 293
Q++ P N KE Q+ + AD +Q ++ +V + E + N +
Sbjct: 1142 QAEPARENDPTVNIKEPQSQTN-----TTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196

Query: 294 SSQLSSNNMNGNHYINDKRDTLKALEQDVNQQSDFNNQRKQALKQDIRQTEQRMN 348
+ ++ +N + + +S +N + R T +
Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCD 1251


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00990FLGFLGJ561e-10 Flagellar protein FlgJ signature.
		>FLGFLGJ#Flagellar protein FlgJ signature.

Length = 313

Score = 56.3 bits (135), Expect = 1e-10
Identities = 55/211 (26%), Positives = 92/211 (43%), Gaps = 20/211 (9%)

Query: 324 VNPQLPTPDELKHKTKPAQSFEGDFKQSNTRATGLFQQLPKIEDGALTDGDINIVDSKST 383
+ P+ P P+E E + N + L Q+ GD +
Sbjct: 98 MTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGD--------S 149

Query: 384 RDFIKSIAKDAHQIGQKEDLYASVMMAQAILESDSGNSALAQ---KPNFNLFGIK--GTY 438
+ F+ ++ A Q+ + +++AQA LES G + + +P++NLFG+K G +
Sbjct: 150 KAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNW 209

Query: 439 QGQSVSFNTLEADSTNNMFNITAGFRKYPDTKASLEDYARLIKKGIDGNPNIYRPTWKSE 498
+G T E ++ + A FR Y +L DY L+ + NP T +
Sbjct: 210 KGPVTEITTTEYEN-GEAKKVKAKFRVYSSYLEALSDYVGLLTR----NPRYAAVT--TA 262

Query: 499 ASTYQSATSHLSRTYATDPNYAKKLNSIIKH 529
AS Q A + YATDP+YA+KL ++I+
Sbjct: 263 ASAEQGAQALQDAGYATDPHYARKLTNMIQQ 293


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS00995ABC2TRNSPORT427e-06 ABC-2 type transport system membrane protein signat...
		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

signature.
Length = 262

Score = 41.8 bits (98), Expect = 7e-06
Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 825 PVLFVTIAVFCSLVFNSIIYTCVSLLGNPGKAIAIIFLVLQIAG----GGGTFPIQTTPK 880
PV+ +T F SL ++ T ++ P I + L I G FP+ P
Sbjct: 152 PVIALTGLAFASL---GMVVTALA----PSYDYFIFYQTLVITPILFLSGAVFPVDQLPI 204

Query: 881 FFQTISPYLPFTYAIDALRETV-----GGIVPEILITKVIILALFGLGFIIVGVI 930
FQT + +LP +++ID +R + + + + I+ F F+ ++
Sbjct: 205 VFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPF---FLSTALL 256


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01000DHBDHDRGNASE1312e-39 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 131 bits (331), Expect = 2e-39
Identities = 75/252 (29%), Positives = 129/252 (51%), Gaps = 2/252 (0%)

Query: 4 QNKVAIVTGAAQGIGFEIAKRLFNDGFNVALVDYNEQGAKEAAATLKGKGQEAIAFKADV 63
+ K+A +TGAAQGIG +A+ L + G ++A VDYN + ++ ++LK + + A AF ADV
Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66

Query: 64 ANRDEVFHVFSQVVKHFGELNVVVNNAGLGPMTPIDTVTTEQFNQVIGVNVGGVFWGIQA 123
+ + + +++ + G ++++VN AG+ I +++ E++ VN GVF ++
Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

Query: 124 ALEQFEALGHGGKIINATSQAGVEGNKGLSLYCSSKFAVRGLTQVAARDLADKGITVNAF 183
+ G + ++ AGV ++ Y SSK A T+ +LA+ I N
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVP-RTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185

Query: 184 APGIVETPMMEGIAIKLAKENNQPEEWGWKQFTDQITLKRLSKPEDVANVVSFLAGSDSD 243
+PG ET M + + + F I LK+L+KP D+A+ V FL +
Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSL-ETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244

Query: 244 YITGQTIIVDGG 255
+IT + VDGG
Sbjct: 245 HITMHNLCVDGG 256


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01005VACCYTOTOXIN270.041 Helicobacter pylori vacuolating cytotoxin signature.
		>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature.

Length = 1291

Score = 27.3 bits (60), Expect = 0.041
Identities = 14/67 (20%), Positives = 28/67 (41%), Gaps = 1/67 (1%)

Query: 50 KEKAKNNTTDQETVQAEPTNSQQNNVNKSNHSANQQPTQKSSQATHQTSPSQSTQAKPSN 109
+ N E + N + +N ++N ++Q + +++ T +P S Q K
Sbjct: 317 QSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ-KTEI 375

Query: 110 QPAQKSN 116
QP Q +
Sbjct: 376 QPTQVID 382


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS01025THERMOLYSIN400e-137 Thermolysin metalloprotease (M4) family signature.
		>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature.

Length = 544

Score = 400 bits (1029), Expect = e-137
Identities = 169/491 (34%), Positives = 240/491 (48%), Gaps = 49/491 (9%)

Query: 58 KNAKKQFK-------HYKTVDVNTDQLGYTHYTLQPKFKNAYVPDREVKIHTNPQGKVVL 110
K F+ + D+LG+T + + + H N G++
Sbjct: 60 DQEKNTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVND-GELSS 118

Query: 111 ING----DTGGSEIKPSNTVQIHKKEAINKAFEAISMSSDNAKNFKNDVIKKNQIQISGQ 166
++G + +K + I + E I K A ++ + + + I +
Sbjct: 119 LSGTLIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAA-EEGKPTRLVIYPDEE 177

Query: 167 HNKYVYQVEIVTTSPKISHWNIQVDAETGEVIDKINNIQHAH-----------TEGTGKS 215
+ Y+V + +P +W +DA G+V++K N + A T G G+
Sbjct: 178 TPRLAYEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRG 237

Query: 216 VLNKTKKINI--NSKDKGYELKDVTHKGNISAYDYNDEDG-SSKLMTDKDKEFVDKSQHA 272
VL K IN +S Y L+D T I YD + L D D +F A
Sbjct: 238 VLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFASYDAA 297

Query: 273 AVDANDYAKDVYDYYKNKFGRESYDDKGSPIDSLTHVNQFENEDNRNNAAWIGDKMIYGD 332
AVDA+ YA VYDYYKN GR SYD + I S H + NNA W G +M+YGD
Sbjct: 298 AVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGR-----GYNNAFWNGSQMVYGD 352

Query: 333 GDNDNYLPFSGAKDVVAHEITHGITQETANLVYENQPGALNESFSDVFAYFID-----SD 387
GD +LPFSG DVV HE+TH +T TA LVY+N+ GA+NE+ SD+F ++ +
Sbjct: 353 GDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNP 412

Query: 388 NFLIGEDIYTPNVKGDALRSMSNPEKYDQPAHMKHYSKTQEDNGGVHTNSGIPNKAAYL- 446
++ IGEDIYTP V GDALRSMS+P KY P H +DNGGVHTNSGI NKAAYL
Sbjct: 413 DWEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLL 472

Query: 447 ---------TIKRIGKDKAEQIYYRTLTHYLSSNSDFEDAKKSLHQAALDLYDKSTAD-- 495
++ IG+DK +I+YR L +YL+ S+F + + QAA DLY ++ +
Sbjct: 473 SQGGVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVN 532

Query: 496 QVNQSWEDVGV 506
V Q++ VGV
Sbjct: 533 SVKQAFNAVGV 543


28EL082_RS02420EL082_RS02465N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS02420-2100.057386GNAT family N-acetyltransferase
EL082_RS02425-2100.010003acryloyl-CoA reductase
EL082_RS02430-211-0.816595imelysin
EL082_RS02435-211-1.296871deferrochelatase/peroxidase EfeB
EL082_RS02440-210-1.770138FTR1 family protein
EL082_RS02445-29-2.290242twin-arginine translocase subunit TatC
EL082_RS02450-411-1.711998twin-arginine translocase TatA/TatE family
EL082_RS02455-411-1.610166GNAT family N-acetyltransferase
EL082_RS02460-411-1.364709bifunctional glycosyltransferase family 2
EL082_RS02465-310-1.147954hypothetical protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02420SACTRNSFRASE383e-06 Streptothricin acetyltransferase signature.
		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

Length = 173

Score = 38.0 bits (88), Expect = 3e-06
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 1/76 (1%)

Query: 45 YHDSSLIGMGRIVGDGGTALQIVDIAVHPDYQGQGYGRTIMEHIMQYVHDNAVKGTYVSL 104
Y +++ IG +I + I DIAV DY+ +G G ++ +++ +N G +
Sbjct: 71 YLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLET 130

Query: 105 MA-DYPADKLYEKFGF 119
+ A Y K F
Sbjct: 131 QDINISACHFYAKHHF 146


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02440ACRIFLAVINRP340.002 Acriflavin resistance protein family signature.
		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

Length = 1034

Score = 34.0 bits (78), Expect = 0.002
Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 5/81 (6%)

Query: 448 EGVEVIIFYMGMI---GSITTKDFILGIGLAIIILIIFAFAFRFIVKLIPVRFIFRVLSI 504
+G++V+ Y SI L + ++ L+++ F LIP + VL
Sbjct: 319 QGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLG 378

Query: 505 LIFVMTFKMLGVSIQKLQLLG 525
++ G SI L + G
Sbjct: 379 TFAIL--AAFGYSINTLTMFG 397


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02450TATBPROTEIN304e-04 Bacterial sec-independent translocation TatB protein...
		>TATBPROTEIN#Bacterial sec-independent translocation TatB protein

signature.
Length = 171

Score = 30.0 bits (67), Expect = 4e-04
Identities = 11/40 (27%), Positives = 23/40 (57%)

Query: 11 GPTSLVIISIIALIIFGPTKLPQFGRAIGSTLKEFKSAAE 50
G + L+++ II L++ GP +LP + + ++ +S A
Sbjct: 5 GFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT 44


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02455SACTRNSFRASE431e-07 Streptothricin acetyltransferase signature.
		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

Length = 173

Score = 42.6 bits (100), Expect = 1e-07
Identities = 23/117 (19%), Positives = 45/117 (38%), Gaps = 8/117 (6%)

Query: 31 YTDDNLQK-YFDSAFNIETLKKELQEPLSFYYFFTEDDDIVGYTKFNVDDAQTEPHGPDY 89
YT++ K YF + + ++E + + +++ +G K + Y
Sbjct: 37 YTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIR-------SNWNGY 89

Query: 90 LEVQRIYFYQSHQGGGRGKKLIELAVEKAKAFGKSKIWLGVWEHNPQAIKFYESRGF 146
++ I + ++ G G L+ A+E AK + L + N A FY F
Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02465adhesinb280.038 Adhesin B signature.
		>adhesinb#Adhesin B signature.

Length = 310

Score = 27.9 bits (62), Expect = 0.038
Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 1 MKKLYTSLLALSLVLGAAACSNDDSSKDKDSSK 33
MKK +L L +G AACS+ SS + SSK
Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSK 33


29EL082_RS02505EL082_RS02545N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS02505-312-2.342055response regulator transcription factor
EL082_RS02510-313-1.859752ABC transporter permease
EL082_RS02515-214-2.408987ABC transporter ATP-binding protein
EL082_RS02520-211-2.078790YdcF family protein
EL082_RS02525-39-1.247173tcaA protein
EL082_RS02530-310-1.401625multidrug effflux MFS transporter
EL082_RS02535-212-0.838559TetR/AcrR family transcriptional regulator
EL082_RS02540-312-1.464567HlyD family secretion protein
EL082_RS02545-211-0.689320DHA2 family efflux MFS transporter permease
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02505HTHFIS845e-21 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 84.1 bits (208), Expect = 5e-21
Identities = 32/118 (27%), Positives = 55/118 (46%), Gaps = 1/118 (0%)

Query: 3 RCLIVDDDPKILNYVSTHLEREHFHTYTHTNGEEALHFLDNHQVDIAIVDIMMHGMDGFE 62
L+ DDD I ++ L R + +N ++ D+ + D++M + F+
Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

Query: 63 -LCHMIKEDYDLPVIMLTARDALSDKERAFISGTDDYLTKPFEVKELIFRIKAVLRRY 119
L + K DLPV++++A++ +A G DYL KPF++ ELI I L
Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02515PF05272337e-04 Virulence-associated E family protein
		>PF05272#Virulence-associated E family protein

Length = 892

Score = 33.1 bits (75), Expect = 7e-04
Identities = 11/30 (36%), Positives = 17/30 (56%)

Query: 35 IILSGASGSGKSTLLSILGGLLSQTKGEIN 64
++L G G GKSTL++ L GL + +
Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFD 628


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02535TCRTETA702e-15 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 70.2 bits (172), Expect = 2e-15
Identities = 60/321 (18%), Positives = 122/321 (38%), Gaps = 17/321 (5%)

Query: 8 KKQSPIFVIILGALTAIGALSIDMFLPGLPEIKNDFHTTTSNAQ---LTLSLFMIGLALG 64
K P+ VI+ A+ A+ I + +P LP + D + + L+L+ +
Sbjct: 2 KPNRPLIVILS--TVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFAC 59

Query: 65 NLFAGPISDATGRKKPLWISMFIYTLASLGIVFVTNIEIMIALRFIQGVTGGAASVISRA 124
G +SD GR+ L +S+ + + + ++ R + G+TG +V
Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAY 119

Query: 125 IASDMYKGKELTKFLSLLMLVNGVAPVIAPAIGGVILSLAVWRMVFIILTVFGILMVIGS 184
IA D+ G E + + G V P +GG++ + F L +
Sbjct: 120 IA-DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTG 177

Query: 185 LTKVPESLQDDEK-DSDGIKEMFKNFKHLLETPKFVLPMLIQGFSFIMLFTYISASPFII 243
+PES + + + +F+ V ++ F + L + A+ ++I
Sbjct: 178 CFLLPESHKGERRPLRREALNPLASFR-WARGMTVVAALMAVFFI-MQLVGQVPAALWVI 235

Query: 244 --QKIYGMSALQFSIMFAAIGITLIISSQLV-GVLVDRIERRQLLKIVTYIQVLGVVIVA 300
+ + A I AA GI ++ ++ G + R+ R+ L + G +++A
Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295

Query: 301 ITLLNHLSFWILVIGFIILVA 321
W+ ++L +
Sbjct: 296 FA----TRGWMAFPIMVLLAS 312


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02540HTHTETR482e-09 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 48.1 bits (114), Expect = 2e-09
Identities = 13/54 (24%), Positives = 24/54 (44%)

Query: 2 KRRAKFKIIQSMINLLDEYPFDEITIKMICAYSGVNRSTFYDNYKDKYDLLEQI 55
+ + I+ + L + ++ I +GV R Y ++KDK DL +I
Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02545RTXTOXIND481e-08 Gram-negative bacterial RTX secretion protein D signat...
		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

signature.
Length = 478

Score = 47.5 bits (113), Expect = 1e-08
Identities = 25/134 (18%), Positives = 41/134 (30%), Gaps = 15/134 (11%)

Query: 87 MSIKMPKDGTIVKTD-GMEGSMAQAGNPIAYAYNLDD-LYITANVDEKDVADIEKGNDVD 144
I+ P + + EG + + DD L +TA V KD+ I G +
Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAI 387

Query: 145 VDIDG--QKAT--VSGKVDQIG-DATAASFSLMPSSNSDGNYTKVSQVVPVRISLDSEPS 199
+ ++ + GKV I DA G V + +
Sbjct: 388 IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL--------GLVFNVIISIEENCLSTGNKN 439

Query: 200 KNVVPGMNAEVKIH 213
+ GM +I
Sbjct: 440 IPLSSGMAVTAEIK 453



Score = 33.6 bits (77), Expect = 4e-04
Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 4/66 (6%)

Query: 14 VLIVIGVVGFYFWNNATSY--VSTDNAKV--DGDQMKIASPASGEIKSLDVKQGEKLKKG 69
I+ +V + + V+T N K+ G +I + +K + VK+GE ++KG
Sbjct: 62 YFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKG 121

Query: 70 DKVAEV 75
D + ++
Sbjct: 122 DVLLKL 127


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS02550TCRTETB1532e-42 Tetracycline resistance protein TetB signature.
		>TCRTETB#Tetracycline resistance protein TetB signature.

Length = 458

Score = 153 bits (387), Expect = 2e-42
Identities = 86/414 (20%), Positives = 180/414 (43%), Gaps = 14/414 (3%)

Query: 157 KILAAMLFGMFIAILNQTLLNVALPKINTEFNISASTGQWLMTGFMLVNGILIPISAFLF 216
+IL + F ++LN+ +LNV+LP I +FN ++ W+ T FML I + L
Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73

Query: 217 NKYSYRKLFIIGLVLFTIGSLICAISMN-FPVMMSGRILQAIGAGILMPLGSNVIVTIFP 275
++ ++L + G+++ GS+I + + F +++ R +Q GA L V+ P
Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133

Query: 276 PEKRGVAMGTMGIAMILAPAIGPTLSGYIVQNYDWNLMFYGMFFIGLVAIAVGFFWFRLY 335
E RG A G +G + + +GP + G I W+ + I ++ + +
Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP-MITIITVPFLMKLLKKE 192

Query: 336 QRTTNPKADVPGIIYSTIGFGALLYGFSEAGNKSWGSTEIVSMFIIGIIFIALFVIRELR 395
R D+ GII ++G + + S I+ ++ +FV +
Sbjct: 193 VRIKGH-FDIKGIILMSVGIVFFMLF---TTSYSIS------FLIVSVLSFLIFVKHIRK 242

Query: 396 MKAPMLNLEVLKYPTYTLTTVINMIVMMSLYGGMILLPIYLQNLRGFSALDSG-LLMLPG 454
+ P ++ + K + + + I+ ++ G + ++P ++++ S + G +++ PG
Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302

Query: 455 ALVMGALGPIAGKLLDTIGIKPLAIFGIGVMTYATWELTKLNMDTPYLSIMGIYVLRSFG 514
+ + G I G L+D G + G+ ++ + + L T + + I V G
Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIII-VFVLGG 361

Query: 515 MAFIMMPIMTAGMNALPARLISHGNAFVNTMRQLAGSIGTAILVTVMTTQTTNH 568
++F I T ++L + G + +N L+ G AI+ +++ +
Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415


30EL082_RS03375EL082_RS03400N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS03375-212-1.683859Asp23/Gls24 family envelope stress response
EL082_RS03380-211-1.321102siderophore biosynthesis protein
EL082_RS03385-211-1.080703MFS transporter
EL082_RS03390-112-0.692726siderophore synthetase
EL082_RS03395013-0.759716alanine racemase
EL082_RS03400111-0.492291ABC transporter substrate-binding protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS0338056KDTSANTIGN310.003 Rickettsia 56kDa type-specific antigen protein sign...
		>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein

signature.
Length = 533

Score = 30.7 bits (69), Expect = 0.003
Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 11 AYDNQTGVNEKERQEQQKQQQQQENQQPQ 39
A+ NQ +N + Q+QQ Q + QQ Q
Sbjct: 325 AFVNQIHLNFVMPPQAQQQQGQGQQQQAQ 353


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03385PF041832252e-67 IucA / IucC family
		>PF04183#IucA / IucC family

Length = 580

Score = 225 bits (574), Expect = 2e-67
Identities = 95/579 (16%), Positives = 210/579 (36%), Gaps = 61/579 (10%)

Query: 93 SHKKLYAPIS---GQHAFNRVDVE-------GPFYYQSINDSSFYRVEHPNDILEWVLIE 142
+++++ S ++ N + G + + I+ + + P +L++
Sbjct: 22 EYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQ-TLLMQ 80

Query: 143 APE---LDNEASDQFKDDLTNSAANMIFAISYQAYSMKGESQPLFDIIKNHNDSYLRSEQ 199
+ + + + DL + + + + D+I + D Q
Sbjct: 81 LKQVLSMSDATVAEHMQDLYATLLGDLQLLKAR------RGLSASDLINLNADR----LQ 130

Query: 200 AVIEGHPLHPGAKLRKGMDSSETFKYSPEFAQPIDLKIILIHHQFSKVQSLDKSYNDTIN 259
++ GHP K R+G +Y+PE+A L + + + + I+
Sbjct: 131 CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC---DNEMDIH 187

Query: 260 QLFPS-MYQQLLDEIKQY--DDINIDDYHVMIVHPWQYDEVLDRDYSKELDQ-HMIIKTQ 315
QL + M Q Q ++ ++ + VHPWQ+ + + D+ + + M+ +
Sbjct: 188 QLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGE 247

Query: 316 CTLPYYAGLSFRTLMPKAPNEDPHIKLSTNVHITGEIRTLSEQTTHNGPLVTHILNQILV 375
+ A S RTL + IKL ++ T R + + GPL + L Q+
Sbjct: 248 FGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFA 307

Query: 376 NDTTFKPYASSVIDEVAGIHFYNENDLDPIQTER--SEQLGTLFRTNINTHLKQNGLTSM 433
D T + ++ E A + +E + E LG ++R N LK + + +
Sbjct: 308 TDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDE-SPV 366

Query: 434 IPSSLVAQYPYHPEPPIVSLIKLYQSHHKFTSYDEAALTWMKDYSHALLGLVVPLLTKYG 493
+ ++L+ + +P + I A TW+ ++ + LL +YG
Sbjct: 367 LMATLMECDENN-QPLAGAYID---------RSGLDAETWLTQLFRVVVVPLYHLLCRYG 416

Query: 494 IALEAHLQNAIVHFNEDGSLNHLYVRDFEG-LRIDQARLNDMGYATDQFHEKSRILTESK 552
+AL AH QN + ++G + ++DF+G +R+ + +M E + +
Sbjct: 417 VALIAHGQNITLAM-KEGVPQRVLLKDFQGDMRLVKEEFPEMD---SLPQEVRDVTSRLS 472

Query: 553 VSVFNKAFYSTVQNHLGELILTIVQSADHKNLEDIIWNDIANIIHQILDTMTDVPNERIS 612
+ + I ++ E + +A ++ + + +ER +
Sbjct: 473 ADYLIHDLQTGHFVTVLRFISPLMVRLGVP--ERRFYQLLAAVLSDYMKKHPQM-SERFA 529

Query: 613 EIQNVMFAKTIDYKCVTTMRLEDEAHEYTYIKVNNPLHS 651
+F I + ++L T+ ++
Sbjct: 530 LFS--LFRPQIIRVVLNPVKL-------TWPDLDGGSRM 559


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03390TCRTETA417e-06 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 40.6 bits (95), Expect = 7e-06
Identities = 44/317 (13%), Positives = 96/317 (30%), Gaps = 27/317 (8%)

Query: 4 FFFSSSFLLFLGNWIGQIGLNWFVLTTYHN--------AVYLGLVNFCRLVPILLLSVWA 55
S+ L +G IGL VL + G++ + +
Sbjct: 9 VILSTVALDAVG-----IGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL 63

Query: 56 GSIADKYDKGNLLRITISSSFLVTAILCVMTYSFNQIPVYIVLIYATLRGMLSAVETPVR 115
G+++D++ + R + S A+ + P VL + ++ V
Sbjct: 64 GALSDRFGR----RPVLLVSLAGAAVDYAI---MATAPFLWVLYIGRIVAGITGATGAVA 116

Query: 116 QAVLPDLSDKITTTQAVSFHSFIINICRSIGPAIAGVILAVYHAPTTFLAQA--ICYLIA 173
A + D++D + F S GP + G++ F A A +
Sbjct: 117 GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT 176

Query: 174 VALCLPIHIQATDLGEHQKEMSLKVVLDYFKRNLEGSKIFFTSLLIMATGFSYTTILPVL 233
LP + ++ ++ + + + + ++ G + +
Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIF 236

Query: 234 TNHVFPGQSEIFGIAMTCCAIGGIIATVI----LPKILDHIDAVKMYYLSSLLFGIALLG 289
F + GI++ I +A + + L A+ + ++ G LL
Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGT-GYILLA 295

Query: 290 IIVHNLVMMFICITLIG 306
+ I + L
Sbjct: 296 FATRGWMAFPIMVLLAS 312


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03395PF041832116e-63 IucA / IucC family
		>PF04183#IucA / IucC family

Length = 580

Score = 211 bits (538), Expect = 6e-63
Identities = 96/458 (20%), Positives = 176/458 (38%), Gaps = 56/458 (12%)

Query: 164 VLEGHPTHPLTKTKLPLTSEEIRRYAPEFEKIIPLHIMLVSSSHIRTTSMEND--EQYIV 221
+L GHP K + E + RYAPE+ LH + V H+ Q +
Sbjct: 132 LLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLT 191

Query: 222 NQVIPELKDKLQSFLKPLDLEMNNYRAIFVHPWQYDHVIGERFKTWISEKILIPT-PFTV 280
+ P+ + + L+ +N+ + VHPWQ+ I F +E ++ F
Sbjct: 192 AAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGD 250

Query: 281 ESKATLSFRTMELLHHP--FHIKLPVNVQATSAVRTVSTVTTVDGPKLSYALQ-----DM 333
+ A S RT+ IKLP+ + TS R + GP S LQ D
Sbjct: 251 QWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDA 310

Query: 334 LNIYPELKVSAEPFGEYVDVDA---------DLARQLACIVREKP--VLAQEGSTIVSAS 382
+ + EP YV + L I RE P L + S ++ A+
Sbjct: 311 TLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMAT 370

Query: 383 LVNRNPVDDDVIVDSYIKWINNELTTESIEQFIRQYTSTLVRPLIAYIQDYGIALEAHMQ 442
L+ + ++ + +YI + + E ++ Q +V PL + YG+AL AH Q
Sbjct: 371 LMECDE-NNQPLAGAYI-----DRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQ 424

Query: 443 NTIVNLGPNYQMNFLVRDLGGS-RI------DLQTLKHKLPDV--KITNESLIADSIEAV 493
N + + L++D G R+ ++ +L ++ DV +++ + LI D
Sbjct: 425 NITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGH 484

Query: 494 -IGKFQHAVVQNQLAELIHHFNQYDMVNEERLFKIVQQEIEAAIDANKNHAQALHRV-LF 551
+ + ++ L+ V E R ++++ + + + ++ LF
Sbjct: 485 FVTVLRF------ISPLMVRLG----VPERRFYQLLAAVLSDYMKKHPQMSERFALFSLF 534

Query: 552 GPTISVKALLSMRM-----ENKVKKYLN--TELENPIK 582
P I L +++ + + N +L+NP+
Sbjct: 535 RPQIIRVVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLW 572


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03400ALARACEMASE300.012 Alanine racemase signature.
		>ALARACEMASE#Alanine racemase signature.

Length = 356

Score = 30.1 bits (68), Expect = 0.012
Identities = 60/334 (17%), Positives = 115/334 (34%), Gaps = 47/334 (14%)

Query: 4 IKINLSKIQYNAKVLQTILDAKHIQFTPVIKSIA---GDLQIVQKLIELGITHFADSRLE 60
++L ++ N +++ A H + V+K+ A G +I + FA LE
Sbjct: 7 ASLDLQALKQNLSIVRQA--ATHARVWSVVKANAYGHGIERIWSAIGATDG--FALLNLE 62

Query: 61 NIRQLTNFDCSFTILRSTQLSQLDNMIKDTQISIQTELNTII---ELNRIAQHLNIKHQ- 116
L IL D +I Q L T + + Q+ +K
Sbjct: 63 EAITLRERGWKGPILMLEGFFHAQ----DLEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118

Query: 117 -VILMVDWKDGREGVLTYDVVKYIETILNLSHIQLVGVSFNFMCFKSSSPIEDDVFMINK 175
+ L V+ R G V+ + + ++++ + + +F + I + I +
Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQ 178

Query: 176 FVSAIEREIGYRMKIVSGGNSSMLPLTMYNDLGKINELRIGETLFRGVDTTTD--KPVSH 233
+E S NS+ T+++ + +R G L+ G + +
Sbjct: 179 AAEGLECR-------RSLSNSAA---TLWHPEAHFDWVRPGIILY-GASPSGQWRDIANT 227

Query: 234 LYQDAIVLEAEILEIKPRMNSHTKQSY----------LQAIVDIGYIDTDTTHIS---PI 280
+ + L +EI+ ++ + + + Y IV GY D H P+
Sbjct: 228 GLRPVMTLSSEIIGVQ-TLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPV 286

Query: 281 ANDIQ---IIGA-SSDHLMIDLNNQDHYQIGNKI 310
D +G S D L +DL IG +
Sbjct: 287 LVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPV 320


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS03405FERRIBNDNGPP825e-20 Ferrichrome-binding periplasmic protein signature.
		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

Length = 296

Score = 82.3 bits (203), Expect = 5e-20
Identities = 55/254 (21%), Positives = 102/254 (40%), Gaps = 20/254 (7%)

Query: 58 PKRVVVLEYSFVDALAALDVKPVGVAD-DNKKERIIKP-LRDKIGNYTSVGARKQPNLEE 115
P R+V LE+ V+ L AL + P GVAD N + + +P L D + + VG R +PNLE
Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVID---VGLRTEPNLEL 91

Query: 116 ISKLKPDLIIADSNRHKGIYKDLNKIAPTIELKSFDGN--YDDNIDAFKTISKALGKEDE 173
++++KP ++ S + + L +IAP DG + ++ L +
Sbjct: 92 LTEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSA 150

Query: 174 GKKRLKEHDKKIAEYK-KDIKFDKDEKVLPAVAAKSSFLGHPSESYVGQFLTQLGFKEAL 232
+ L +++ I K + +K +L + L S + L + G A
Sbjct: 151 AETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAW 210

Query: 233 SPDVTKGLSKYLKGPYLEMNSETLSDVNPGRMFIMTDKASPDEPTFKKMQKDPVWKKLDA 292
+G + + + + + L+ + S D + P+W+ +
Sbjct: 211 -----QGETNFWGSTAVSI--DRLAAYKDVDVLCFDHDNSKDMD---ALMATPLWQAMPF 260

Query: 293 VKNDRVDVVDRDLW 306
V+ R V +W
Sbjct: 261 VRAGRFQRVP-AVW 273


31EL082_RS04090EL082_RS04110N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS04090-3110.421789sulfurtransferase TusA family protein
EL082_RS04095-19-0.965547LacI family DNA-binding transcriptional
EL082_RS0410009-1.231415sucrose-6-phosphate hydrolase
EL082_RS04105111-1.894520carbohydrate kinase
EL082_RS04110413-2.930031response regulator transcription factor
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS04095PF01206561e-14 SirA family protein
		>PF01206#SirA family protein

Length = 76

Score = 55.9 bits (135), Expect = 1e-14
Identities = 11/72 (15%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 3 YELGTVGMVCPFPLIEAQKKMTELDLGDELKIDFDCTQATEAIPNWAAENGYPVTNYEQL 62
L G+ CP P+++A+K + ++ G+ L + + + +++ + G+ + ++
Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65

Query: 63 GDASWTITVQKA 74
+ +++A
Sbjct: 66 DGT-YHFRLKRA 76


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS04100HTHTETR280.047 TetR bacterial regulatory protein HTH signature.
		>HTHTETR#TetR bacterial regulatory protein HTH signature.

Length = 215

Score = 27.7 bits (61), Expect = 0.047
Identities = 6/21 (28%), Positives = 13/21 (61%)

Query: 4 ISDIAKLAGVSKSTVSRYLNN 24
+ +IAK AGV++ + + +
Sbjct: 34 LGEIAKAAGVTRGAIYWHFKD 54


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS04105OUTRSURFACE290.034 Outer surface protein signature.
		>OUTRSURFACE#Outer surface protein signature.

Length = 273

Score = 29.1 bits (65), Expect = 0.034
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 24/102 (23%)

Query: 396 STMISYNKRDNKVTLDRTD-SGVLPGNVEGTTRSTKLDSTLTQLRIFVD--TSSIEIFCN 452
S + +K + K T D+ + SGVL G TK D + +L I D ++ E+F
Sbjct: 53 SLKATVDKIELKGTSDKDNGSGVLEG--------TKDDKSKAKLTIADDLSKTTFELFKE 104

Query: 453 DGERVLTSRIFPSEEATGIKTSTESGQVYLQFTKYKLKGDLS 494
DG+ +++ ++ + KTST+ + KG+LS
Sbjct: 105 DGKTLVSRKVSSKD-----KTSTD--------EMFNEKGELS 133


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS04115HTHFIS337e-04 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 33.3 bits (76), Expect = 7e-04
Identities = 16/134 (11%), Positives = 42/134 (31%), Gaps = 13/134 (9%)

Query: 2 KIFICEDDPKQRENMASIIKNYIMIEEKPMELALATDDPYEVLEQSKNMNDIGCYFLDIQ 61
I + +DD R + + + + + + D+
Sbjct: 5 TILVADDDAAIRTVLNQAL----SRAGYDVRITSNAATLWRWIAAGDG----DLVVTDVV 56

Query: 62 LEADINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFK----DDPAELK 117
+ D N L I+K P ++ +++ + + A D++ K + +
Sbjct: 57 M-PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115

Query: 118 TRIIDCLETAHTRL 131
R + + ++L
Sbjct: 116 GRALAEPKRRPSKL 129


32EL082_RS05525EL082_RS05560N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS05525417-6.125799prepilin peptidase
EL082_RS05530117-3.950869DNA repair protein RadC
EL082_RS05535318-5.059841hypothetical protein
EL082_RS05540015-4.321489hypothetical protein
EL082_RS05545-114-3.370626DUF4930 family protein
EL082_RS05550014-2.069744hypothetical protein
EL082_RS05555012-0.066448rod shape-determining protein MreC
EL082_RS05560114-0.251372rod shape-determining protein MreD
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05525PREPILNPTASE642e-14 Type IV prepilin cysteine protease (C20) family sig...
		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

signature.
Length = 290

Score = 64.4 bits (157), Expect = 2e-14
Identities = 43/203 (21%), Positives = 86/203 (42%), Gaps = 15/203 (7%)

Query: 32 RSQCDFCQSKLKYYDLIPIISFLILKGKSRCCKQSLNYSYLIGELLALLPILLVYYQL-I 90
RS C C + + IP++S+L L+G+ R C+ ++ Y + ELL L + V L
Sbjct: 71 RSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAP 130

Query: 91 NINPQLYLISFLFLLVMSINDIEDYSI-NLYFLIIFTTVLLFTTQIFLNT---------- 139
L+ L+ ++ D++ + + L + LLF +
Sbjct: 131 GWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMA 190

Query: 140 -FILTFIISHLFYIFMNHY-IGYGDILLFNILSLFLSMNFMFYLILFTFMIGGLITIIIK 197
+++ + + F + +GYGD L L +L + ++L + ++G + I +
Sbjct: 191 GYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLI 250

Query: 198 TFFNHNI-KYIPLIPFIFLSFIF 219
NH+ K IP P++ ++
Sbjct: 251 LLRNHHQSKPIPFGPYLAIAGWI 273


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS0554560KDINNERMP280.017 60kDa inner membrane protein signature.
		>60KDINNERMP#60kDa inner membrane protein signature.

Length = 548

Score = 28.0 bits (62), Expect = 0.017
Identities = 10/31 (32%), Positives = 15/31 (48%)

Query: 19 IIIYIALKYAPFLRDQEWNPISNPPNQTEQN 49
++ IAL + F+ Q W NP Q +Q
Sbjct: 6 NLLVIALLFVSFMIWQAWEQDKNPQPQAQQT 36


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS05555PF02370280.036 M protein repeat
		>PF02370#M protein repeat

Length = 168

Score = 27.8 bits (61), Expect = 0.036
Identities = 10/20 (50%), Positives = 16/20 (80%)

Query: 79 KQLEAKNQRLEAENKKYKKE 98
K+LE K+Q+L E++K K+E
Sbjct: 147 KELEPKHQKLGTEHQKLKEE 166


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS0556060KDINNERMP280.025 60kDa inner membrane protein signature.
		>60KDINNERMP#60kDa inner membrane protein signature.

Length = 548

Score = 27.6 bits (61), Expect = 0.025
Identities = 12/49 (24%), Positives = 23/49 (46%), Gaps = 2/49 (4%)

Query: 122 YGLIGFIQFNLLEFL--LLRLLPTFILNIILLTILYPIMLKFLRKIQIK 168
YG + FI L + L + + + +II++T + ++ L K Q
Sbjct: 330 YGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYT 378


33EL082_RS06025EL082_RS06095N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS06025216-3.251823rhomboid family intramembrane serine protease
EL082_RS06030012-2.998697DUF910 family protein
EL082_RS06035-214-2.789166ROK family glucokinase
EL082_RS06045-117-4.788778MTH1187 family thiamine-binding protein
EL082_RS06050020-5.184830MBL fold metallo-hydrolase
EL082_RS06055116-4.696509type II secretion system F family protein
EL082_RS06060113-3.830246prepilin-type N-terminal cleavage/methylation
EL082_RS06065112-2.246817hypothetical protein
EL082_RS06075113-1.974488AAA family ATPase
EL082_RS06085114-0.642914glycine cleavage system aminomethyltransferase
EL082_RS06090015-0.468757aminomethyl-transferring glycine dehydrogenase
EL082_RS06095113-0.798369aminomethyl-transferring glycine dehydrogenase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06030TCRTETA290.046 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 29.0 bits (65), Expect = 0.046
Identities = 21/115 (18%), Positives = 40/115 (34%), Gaps = 30/115 (26%)

Query: 247 FAGIFGNFVSLSFNTTTISVGASGAIFGLIGSIFAILY---LSKTFDKR----------V 293
A ++ F F+ ++G S A FG++ S+ + ++ +R
Sbjct: 229 PAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADG 288

Query: 294 IGQLLIA-----------LVILIGLSLFMSNINVM------AHLGGFIGGLLITL 331
G +L+A +V+L + M + M G + G L L
Sbjct: 289 TGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAAL 343


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06040PF03309280.045 Bvg accessory factor
		>PF03309#Bvg accessory factor

Length = 271

Score = 28.2 bits (63), Expect = 0.045
Identities = 11/46 (23%), Positives = 22/46 (47%), Gaps = 6/46 (13%)

Query: 5 ILAADIGGTTCKLGIFNTNLDR---IEKWSIHTD---TTDHTGKLL 44
+LA D+ T +G+ + + D +++W I T+ T D +
Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTI 47


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06060BCTERIALGSPF762e-17 Bacterial general secretion pathway protein F signa...
		>BCTERIALGSPF#Bacterial general secretion pathway protein F

signature.
Length = 408

Score = 76.0 bits (187), Expect = 2e-17
Identities = 49/265 (18%), Positives = 111/265 (41%), Gaps = 1/265 (0%)

Query: 92 ERFGNLEATLHESILFLKKQIQVKQSVIKTIQYPVVLMIIFFLILMLLNFTVIPQFKELY 151
E G+L+A L+ + +++ Q++ + + + YP VL ++ ++ +L V+P+ E +
Sbjct: 143 ETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQF 202

Query: 152 QSMNIALSPLQLVLSSFISGLPFFILFLTCIILVIVILIHTSYRNMPTIKQIH-LMSNLP 210
M AL VL + F ++ +L + R H + +LP
Sbjct: 203 IHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLP 262

Query: 211 IIKSYYKIFKTYQLSNELAHFYRNGINLQLIVEIFQQSNSNQFHQYLGDIILKQSNQGEK 270
+I + T + + L+ + + L + I SN + ++ + +G
Sbjct: 263 LIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVS 322

Query: 271 LPNILKQFKCYESDLIKFIEQGEKSGKLDIELTLYSQILVHQFEILAKRHIKFIQPIIFL 330
L L+Q + + I GE+SG+LD L + +F + +P++ +
Sbjct: 323 LHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDREFSSQMTLALGLFEPLLVV 382

Query: 331 MLGIFIVTLYLSIMLPMFDMLQSIN 355
+ ++ + L+I+ P+ + ++
Sbjct: 383 SMAAVVLFIVLAILQPILQLNTLMS 407


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06065BCTERIALGSPG506e-11 Bacterial general secretion pathway protein G signa...
		>BCTERIALGSPG#Bacterial general secretion pathway protein G

signature.
Length = 145

Score = 49.5 bits (118), Expect = 6e-11
Identities = 21/70 (30%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 9 KTKAFTLIEMLLVLLIISLLLILIIPNV--AKQTAHIQSTGCDAQVKMINSQIEAYTLKH 66
K + FTL+E+++V++II +L L++PN+ K+ A Q + + + + ++ Y L +
Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA--VSDIVALENALDMYKLDN 63

Query: 67 NRNPNTIQDL 76
+ P T Q L
Sbjct: 64 HHYPTTNQGL 73


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06075BINARYTOXINB280.013 Binary toxin B family signature.
		>BINARYTOXINB#Binary toxin B family signature.

Length = 764

Score = 28.5 bits (63), Expect = 0.013
Identities = 13/72 (18%), Positives = 27/72 (37%), Gaps = 3/72 (4%)

Query: 92 IIKDKHTLHLINKEKNAEYIF---KNNKIYKQINGKGNITLLNQVSMVKMIKSNDNIIKI 148
+ I +K+ EY F +N + ++ + I + + +++ K IKI
Sbjct: 88 YFQSAIWSGFIKVKKSDEYTFATSADNHVTMWVDDQEVINKASNSNKIRLEKGRLYQIKI 147

Query: 149 ILKVGNPNYNQY 160
+ NP
Sbjct: 148 QYQRENPTEKGL 159


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS06100HELNAPAPROT280.044 Helicobacter neutrophil-activating protein A family ...
		>HELNAPAPROT#Helicobacter neutrophil-activating protein A family

signature.
Length = 153

Score = 28.3 bits (63), Expect = 0.044
Identities = 13/55 (23%), Positives = 22/55 (40%)

Query: 399 DMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDHFADTLIQIANEAKE 453
+A+RLL G P + ET + E + + QI++E+K
Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKF 117


34EL082_RS07490EL082_RS07515N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS07490511-0.214773putative DNA-binding protein
EL082_RS07495511-0.357363signal recognition particle-docking protein
EL082_RS07500312-0.054081chromosome segregation protein SMC
EL082_RS075051120.003112ribonuclease III
EL082_RS07510-2140.671848acyl carrier protein
EL082_RS07515-2150.7305573-oxoacyl-[acyl-carrier-protein] reductase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07495BONTOXILYSIN270.021 Bontoxilysin signature.
		>BONTOXILYSIN#Bontoxilysin signature.

Length = 1196

Score = 26.8 bits (59), Expect = 0.021
Identities = 12/42 (28%), Positives = 23/42 (54%)

Query: 10 LRMNYLFDFYQSLLTDKQRNYLELFYLQDYALSEIADTFNVS 51
L +NY + S++ D+ N L+ FY + Y + D +N++
Sbjct: 334 LNLNYFCQSFNSIIPDRFSNALKHFYRKQYYTMDYTDNYNIN 375


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07505GPOSANCHOR499e-08 Gram-positive coccus surface protein anchor signature.
		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

Length = 539

Score = 48.9 bits (116), Expect = 9e-08
Identities = 40/316 (12%), Positives = 118/316 (37%), Gaps = 6/316 (1%)

Query: 156 IDRRQIIEESAGVLKYKKRKAESVQKLDQTEDNLSRVEDILYDLEGRVEPLKEEAAIAKE 215
+ + + E+++ + + + RKA+ + L+ + + + LE L A ++
Sbjct: 103 KNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 162

Query: 216 YKQLSSEMKKSDVIVTV---HDIDQYTQDNGQLDEQLNDLKSKQANKEAEQSQINQLLQK 272
+ + +D + +L++ L + A+ +
Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222

Query: 273 YKGQRQELDQNIEQLNYHLVKATEEFEKYSGQLNVLEERKKNQSETNARFEEEQDNLMSQ 332
++ +L++ +E + + + + LE R+ + ++
Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 282

Query: 333 LDNLKSEKDQAIQTLDQLKQKQKELNKTIQALESKLYVSDE---QHDEKLEEIKNKYYTL 389
+ L++EK L+ + + LN Q+L L S E Q + + ++++ +
Sbjct: 283 IKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKIS 342

Query: 390 MSEQSDVNNDIRFLEHTINENEAKKSRLDSRLVEAFNQLKDIQNNISNTDKEYQQVQKDM 449
+ + + D+ + EA+ +L+ + + + ++ ++ + + +QV+K +
Sbjct: 343 EASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKAL 402

Query: 450 HNTEQQIKNIEKQLTE 465
++ +EK E
Sbjct: 403 EEANSKLAALEKLNKE 418



Score = 34.7 bits (79), Expect = 0.003
Identities = 26/192 (13%), Positives = 65/192 (33%), Gaps = 15/192 (7%)

Query: 675 TQKDELTTMRHQLK----DYQKQTHEFEKQFQTHQAQSEKLSETYFELSQSYNNLKEKAH 730
+K L + L+ + + +T +A+ L EL ++ +
Sbjct: 148 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 207

Query: 731 GYELELDRLKKQETHLKDEHEEFEFEKNDGY-QSDKSKATLEQKQHHLSEIQAQLKHLEE 789
++ L+ ++ L + E S A ++ + + ++A+ LE+
Sbjct: 208 ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 267

Query: 790 DIEKYTKLSKEGKETTTQTQQQLHQKQSDLAVVKERIKGQQQEIERLD----------KQ 839
+E S + + +++ A ++ + + + L KQ
Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQ 327

Query: 840 LESTEQQLDTVK 851
LE+ Q+L+
Sbjct: 328 LEAEHQKLEEQN 339


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07515ACRIFLAVINRP250.027 Acriflavin resistance protein family signature.
		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

Length = 1034

Score = 25.2 bits (55), Expect = 0.027
Identities = 9/42 (21%), Positives = 17/42 (40%), Gaps = 2/42 (4%)

Query: 33 GADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKYINS 74
GA++LD A+ + E P + K+ D ++
Sbjct: 296 GANALDTAKAIKAKLAELQPFFP--QGMKVLYPYDTTPFVQL 335


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS07520DHBDHDRGNASE1426e-44 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 142 bits (360), Expect = 6e-44
Identities = 87/250 (34%), Positives = 134/250 (53%), Gaps = 13/250 (5%)

Query: 3 KNALVTGASRGIGRSIAIQLAEEGYNV-AVNYAGNQDKAEAVVSEIKEKGVESFAIQANV 61
K A +TGA++GIG ++A LA +G ++ AV+Y N +K E VVS +K + + A A+V
Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDY--NPEKLEKVVSSLKAEARHAEAFPADV 66

Query: 62 ANGDEVKAMIKEVVSQFGSIDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQK 121
+ + + + + G ID+LVN AG+ R L+ + ++EW+ N GVFN +
Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

Query: 122 VTPQMLRQRSGSIINLSSVVGAVGNPGQANYVATKAGVVGLTKSAARELASRGITVNAVA 181
V+ M+ +RSGSI+ + S V A Y ++KA V TK ELA I N V+
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186

Query: 182 PGFIVSDMTDAL--SDELKEQMLD--------QIPLSRFGEDTDIAHTVAFLASEKAKYI 231
PG +DM +L + EQ++ IPL + + +DIA V FL S +A +I
Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246

Query: 232 TGQTIHVNGG 241
T + V+GG
Sbjct: 247 TMHNLCVDGG 256


35EL082_RS09985EL082_RS10020N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS09985-115-2.653425NAD(P)H-binding protein
EL082_RS09990-116-2.619171GNAT family N-acetyltransferase
EL082_RS09995113-2.756665hypothetical protein
EL082_RS10000013-2.568019hypothetical protein
EL082_RS10005214-2.815999GNAT family N-acetyltransferase
EL082_RS10010213-2.747262DUF1129 family protein
EL082_RS10015013-1.584578DUF456 domain-containing protein
EL082_RS10020-114-2.173340MFS transporter
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS09985NUCEPIMERASE270.048 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 27.1 bits (60), Expect = 0.048
Identities = 13/82 (15%), Positives = 32/82 (39%), Gaps = 10/82 (12%)

Query: 1 MKAIILGGNGLVGRELTRQWLKRDQDI-------EIYVVS--RSGNNVISHKNVHNIKGD 51
MK ++ G G +G ++++ L+ + + Y VS ++ +++ K D
Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60

Query: 52 IQHVEQIKSQLPN-QVDYVVDL 72
+ E + + + V
Sbjct: 61 LADREGMTDLFASGHFERVFIS 82


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10000BACINVASINB270.024 Salmonella/Shigella invasin protein B signature.
		>BACINVASINB#Salmonella/Shigella invasin protein B signature.

Length = 593

Score = 27.4 bits (60), Expect = 0.024
Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 5/132 (3%)

Query: 16 SACGKSEEKASL-EKSVDKLEKENKSLKAQKKKLTKQKDDLKDQQDKLQKEVDSTASSEA 74
+A G+++E L E S+ K + A KKLT+ ++ L+ L A +EA
Sbjct: 131 TALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQS----LDPADPGYAQAEA 186

Query: 75 SSTDSNDKDSEKQSNEDKSSSKSSLQQNDQQSTEEKDASKQTQNQSSTTTQSKNNPNQTS 134
+ + + +E + DK++ + D ++ EK + T+ Q + S+N +Q
Sbjct: 187 AVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQNQVSQGE 246

Query: 135 QQNSNNKASTNQ 146
Q N +N A
Sbjct: 247 QDNLSNVARLTM 258


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10005SACTRNSFRASE290.005 Streptothricin acetyltransferase signature.
		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

Length = 173

Score = 28.8 bits (64), Expect = 0.005
Identities = 15/100 (15%), Positives = 34/100 (34%), Gaps = 12/100 (12%)

Query: 48 LRHTNDTILLLEHNQEIKGFIWGHYELQ------------TKTVIIELLYVYPDYRRQGL 95
+ D + + + +E + +Y +IE + V DYR++G+
Sbjct: 47 FKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGV 106

Query: 96 AKQLKMAIEQWAKDIGAVSIQSTIHIKNEAMLNLNRQLGY 135
L +WAK+ + N + + + +
Sbjct: 107 GTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10020TCRTETA513e-09 Tetracycline resistance protein signature.
		>TCRTETA#Tetracycline resistance protein signature.

Length = 399

Score = 51.4 bits (123), Expect = 3e-09
Identities = 64/336 (19%), Positives = 129/336 (38%), Gaps = 23/336 (6%)

Query: 11 KNYKLFV--VNMLLLGMGIAVTVPYLVLFATKDLGMTTKQ---YGLLLALAAISQFTVNS 65
N L V + L +GI + +P L +DL + YG+LLAL A+ QF
Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLP-GLLRDLVHSNDVTAHYGILLALYALMQFACAP 61

Query: 66 IIARFSDTHNINRKFLIITALFMGAISFSIYFFVKDILLFIILYALFQGLFAPAMPQLYA 125
++ SD R+ +++ +L A+ ++I L + + + G+ A
Sbjct: 62 VLGALSD--RFGRRPVLLVSLAGAAVDYAI-MATAPFLWVLYIGRIVAGITGATGAVAGA 118

Query: 126 SARESINVSSSRENAKFANTVLRSMFSLGFLFGPFIGSQLIELNGYSGL-FGGTVSIILF 184
+ + + F + + F G + GP +G + + ++ ++ + F
Sbjct: 119 YIADITDGDERARHFGF----MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174

Query: 185 TLILQVFFYQNLNVKQPISQQQHVEKVAPNMFKDKTLLIPFLA--FILLHIGQWMYTMNM 242
+ + ++P+ ++ + + T++ +A FI+ +GQ +
Sbjct: 175 LTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL-W 233

Query: 243 PLFVTDYLHEKEGHVGYLASLCAGLEVPF-MVILGILSRKLPTRTLLIYGGIFGGAFYFS 301
+F D H +G + L +I G ++ +L R L+ G I G Y
Sbjct: 234 VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYIL 293

Query: 302 ISLFKNFYMMLLGQLFLAFFLAILLGIGISYFQDIL 337
++ +M + LA GIG+ Q +L
Sbjct: 294 LAFATRGWMAFPIMVLLASG-----GIGMPALQAML 324



Score = 40.6 bits (95), Expect = 8e-06
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 8/157 (5%)

Query: 215 MFKDKTLLIPFLAFILLHIGQWMYTMNMPLFVTDYLHEKE--GHVGYLASLCAGLEVPFM 272
M ++ L++ L +G + +P + D +H + H G L +L A ++
Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60

Query: 273 VILGILSRKLPTRTLLIYGGIFGGAFYFSISLFKNFYMMLLGQLFLAFFLAILLGIGISY 332
+LG LS + R +L+ Y ++ +++ +G++ A G +Y
Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AY 119

Query: 333 FQDILPD-----FPGYASTLFANAMVIGQLCGNLLGG 364
DI G+ S F MV G + G L+GG
Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG 156


36EL082_RS10090EL082_RS10110N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS10090-213-1.827608ABC transporter ATP-binding protein
EL082_RS10095-111-1.613039sensor histidine kinase
EL082_RS10100-210-1.025062response regulator transcription factor
EL082_RS10105010-0.862797NAD(P)-dependent oxidoreductase
EL082_RS10110011-0.486593GNAT family N-acetyltransferase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10090PF05272330.001 Virulence-associated E family protein
		>PF05272#Virulence-associated E family protein

Length = 892

Score = 32.7 bits (74), Expect = 0.001
Identities = 12/56 (21%), Positives = 25/56 (44%), Gaps = 8/56 (14%)

Query: 40 GPSGSGKTTLLNVLSSIDYATRGSIKL--NGQSLDKLSNKA------LSNIRKKDI 87
G G GK+TL+N L +D+ + + S ++++ ++ R+ D
Sbjct: 603 GTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADA 658


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10100HTHFIS645e-14 FIS bacterial regulatory protein HTH signature.
		>HTHFIS#FIS bacterial regulatory protein HTH signature.

Length = 484

Score = 63.7 bits (155), Expect = 5e-14
Identities = 27/111 (24%), Positives = 57/111 (51%), Gaps = 1/111 (0%)

Query: 3 ILLVEDDNTLFQELKKELEQWDFNVVGIDDFGNVMDTFEAFNPEIVILDVQLPKYDGFYW 62
IL+ +DD + L + L + ++V + + A + ++V+ DV +P + F
Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65

Query: 63 CRKMRQV-SNVPILFLSSRDNPMDQVMSMELGADDYIQKPFYTNVLIAKLQ 112
++++ ++P+L +S+++ M + + E GA DY+ KPF LI +
Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10105NUCEPIMERASE280.041 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 28.2 bits (63), Expect = 0.041
Identities = 25/129 (19%), Positives = 43/129 (33%), Gaps = 28/129 (21%)

Query: 4 KVLLAGGTGYIGKHLSS----------VIENDADLY-VLSKYPKPEHVNATDMTWLQSDI 52
K L+ G G+IG H+S I+N D Y V K + E + + + D+
Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61

Query: 53 FNYQDVVEAMKEIDIAIFYLDPTKNSAKLTQATAR----------DLNLIAADNFGRAAA 102
+ + + + + S + R D NL N
Sbjct: 62 ADREGMTDLFASGHFERVF-----ISP--HRLAVRYSLENPHAYADSNLTGFLNILEGCR 114

Query: 103 VNHVKKLVY 111
N ++ L+Y
Sbjct: 115 HNKIQHLLY 123


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS10110SACTRNSFRASE408e-07 Streptothricin acetyltransferase signature.
		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

Length = 173

Score = 40.3 bits (94), Expect = 8e-07
Identities = 26/114 (22%), Positives = 43/114 (37%), Gaps = 4/114 (3%)

Query: 50 DYITSSSKAIFVVESNDQLVGYGFVGTETYERTRHEAIVYLGVKKLYQKDGVGQTLINAI 109
Y+ KA F+ + +G + + E I V K Y+K GVG L++
Sbjct: 58 SYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIA---VAKDYRKKGVGTALLHKA 114

Query: 110 EAWSLNHNIRRIEATVVPENDGAVNLFKSAGFQIEGELKDKLYINNKYYNEYVM 163
W+ ++ + N A + + F I G + LY N NE +
Sbjct: 115 IEWAKENHFCGLMLETQDINISACHFYAKHHFII-GAVDTMLYSNFPTANEIAI 167


37EL082_RS11180EL082_RS11215N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS111801191.900231NAD-dependent epimerase/dehydratase family
EL082_RS111857265.553906LysM peptidoglycan-binding domain-containing
EL082_RS111907265.289144cold-shock protein
EL082_RS111957255.229796DUF1304 family protein
EL082_RS112006235.052090LPXTG cell wall anchor domain-containing
EL082_RS112056245.155152hypothetical protein
EL082_RS112105193.830112hypothetical protein
EL082_RS112150110.697835YSIRK-type signal peptide-containing protein
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11185NUCEPIMERASE2332e-77 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 233 bits (597), Expect = 2e-77
Identities = 94/335 (28%), Positives = 149/335 (44%), Gaps = 36/335 (10%)

Query: 1 MKALITGGAGFIGSHIAQKCIQNNIEVHVIDNLST--------GRIENITFVKKEYFYQE 52
MK L+TG AGFIG H++++ ++ +V IDNL+ R+E + F++
Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ-PGFQFHKI 59

Query: 53 DINNLKFVSDLIKKERFDYVIHLAAMVSVVETVQQPGRSNQVNIDATLNILETLRLQHSN 112
D+ + + ++DL F+ V ++V +++ P N+ LNILE R H+
Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR--HNK 117

Query: 113 IKKFLFASSAAVYGQLEGLPKAIHSRID-PRSPYAVQKYAGESYAKIYHQLYHLPTVSLR 171
I+ L+ASS++VYG +P + +D P S YA K A E A Y LY LP LR
Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR 177

Query: 172 FFNVYGPRQNPYSDYSGVIS-ILNHKFNHKETFTFYGDGLQTRDFIYIDDLVEACWLVLH 230
FF VYGP P +L ++ Y G RDF YIDD+ EA +
Sbjct: 178 FFTVYGPWGRPDMALFKFTKAMLE-----GKSIDVYNYGKMKRDFTYIDDIAEAIIRLQD 232

Query: 231 N--------DNVNGN---------VYNLGTGKQTTLKQMVNIFEQHFNYSIPYVYDEERV 273
G VYN+G L + E +
Sbjct: 233 VIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQP 292

Query: 274 GDIKHSYADISPIQS-LGFSPQYSVEKGIQSYLEY 307
GD+ + AD + +GF+P+ +V+ G+++++ +
Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFVNW 327


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11205INTIMIN512e-08 Intimin signature.
		>INTIMIN#Intimin signature.

Length = 939

Score = 50.8 bits (121), Expect = 2e-08
Identities = 76/413 (18%), Positives = 127/413 (30%), Gaps = 40/413 (9%)

Query: 36 TLPVTATDKDGNESQPSTTVVTDTTAPTVPSVNPVTSDDKTITGKAEPGSTVTVTFPDGT 95
+ A D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 96 KASGTTDADGNYVINIPANEDLKGGETLPVTSTDKDGNESEPATTVVTDTTAPSVPTVNP 155
K +G A+ NI + G L S + +G+ TV + P V+
Sbjct: 585 KKNGVAQANVPVSFNI-----VSGTAVLSANSANTNGSGK---ATVTLKSDKPGQVVVSA 636

Query: 156 VTSDDTQITGKAEPGSTVTVTFPDGTKATGKTDADGNYVINIPANED-LKGGETLPVTAT 214
T++ T + V F D TKA+ + I A++ +T T
Sbjct: 637 KTAEMTS------ALNANAVIFVDQTKAS---------ITEIKADKTTAVANGQDAITYT 681

Query: 215 DKDGNESQPST-TVVTDTTAPSVPTVNPVTSD-----DTQITGKAEPGSTVTVTFPDGT- 267
K +P + VT TT + + +D +T S V+ D
Sbjct: 682 VKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAV 741

Query: 268 --KATGTTDADGNYVIDIPANEDLKG-GETLPVTSTDKDGNTSEPASTVVTDTTAPSVPT 324
KA + D G LP + + T + P
Sbjct: 742 DVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPA 801

Query: 325 VNPVTSDDTQITGKAEPGSTVTVTFPDGTKASGTTDADGNYVIDIPSNEDLKGG--ETLP 382
+ V + Q+T K + +T++V D A+ T + ++ S T
Sbjct: 802 IASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCK 861

Query: 383 VTSTDKDGNQSEPAKTVVTDTTAPSVP---TINPVTSEDTQITGKAEPGSTVT 432
+Q+E A + + S Q A+ G T
Sbjct: 862 NFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914



Score = 49.7 bits (118), Expect = 4e-08
Identities = 62/352 (17%), Positives = 111/352 (31%), Gaps = 51/352 (14%)

Query: 122 TLPVTSTDKDGNESEPATTVVTDTTAPSVPTVNPVTSDDTQITGKAEPGSTVTVTFPDGT 181
+ + D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 182 KATGKTDADGNYVINIPANEDLKGGETLPVTATDKDGNESQPSTTVVTDTTAPSVPTVNP 241
K G A+ NI + + + T+ G + + S T
Sbjct: 585 KKNGVAQANVPVSFNIVSGTAVLSANS---ANTNGSGKATVTLKSDKPGQVVVSAKTAEM 641

Query: 242 VTSDDTQITGKAEPGSTVTVTFPDGTKATGTT--------DADGNYVIDIPANEDLKGGE 293
++ + V F D TKA+ T A+G I + +KG +
Sbjct: 642 TSALNAN-----------AVIFVDQTKASITEIKADKTTAVANGQDAITYTV-KVMKGDK 689

Query: 294 TLPVTSTDKDGNTSEPASTVVTDTTAPSVPTVNPVTSDD-------TQITGKAEPGSTVT 346
PV++ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 347 VTFPDGTKASGTTDADGNYVIDIPSNEDLKGGETLPVTSTDKDGNQSEPAKTVVTDTTAP 406
V F D + + + LP + + T
Sbjct: 748 VEFFTTLTI------DDGNIEIVGTGVK----GKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 407 SVPTINPVTSEDTQITGKAEPGSTVTVTFPDGTTATGKTDENGNYVIDIPSN 458
+ P I V + Q+T K + +T++V D TAT Y I P++
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTAT--------YTIATPNS 841



Score = 32.7 bits (74), Expect = 0.006
Identities = 58/346 (16%), Positives = 99/346 (28%), Gaps = 27/346 (7%)

Query: 28 NEDLKGGETLPVTATDKDGNESQPSTTVVTDTTAPT-VPSVNPVTSDDKTITGKAEPGST 86
+ G E + TAT K +Q + V + + T V S N ++
Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628

Query: 87 VTVTFPDGTKASGTTDADGNYVI----------NIPANED-LKGGETLPVTSTDKDGNES 135
A T+ + N VI I A++ +T T K
Sbjct: 629 PGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGD 688

Query: 136 EP-ATTVVTDTTAPSVPTVNPVTSD-----DTQITGKAEPGSTVTVTFPDGT---KATGK 186
+P + VT TT + + +D +T S V+ D KA
Sbjct: 689 KPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748

Query: 187 TDADGNYVINIPANEDLKG-GETLPVTATDKDGNESQPSTTVVTDTTAPSVPTVNPVTSD 245
+ + G LP + S T + P + V +
Sbjct: 749 EFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDAS 808

Query: 246 DTQITGKAEPGSTVTVTFPDGTKATGTTDADGNYVIDIPANEDLKGG--ETLPVTSTDKD 303
Q+T K + +T++V D AT T + ++ + T
Sbjct: 809 SGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLP 868

Query: 304 GNTSEPASTVVTDTTAPSVP---TVNPVTSDDTQITGKAEPGSTVT 346
+ +E + A + + S Q A+ G T
Sbjct: 869 SSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11210INTIMIN469e-07 Intimin signature.
		>INTIMIN#Intimin signature.

Length = 939

Score = 46.2 bits (109), Expect = 9e-07
Identities = 63/347 (18%), Positives = 109/347 (31%), Gaps = 43/347 (12%)

Query: 932 TLPVTATDKDGNKSEPATTVVTDTTAPTVPSVNPVTSDDTQITGKAEPGSTVTVTFPDGN 991
+ A D++GN S +T + V VT T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 992 TASGTTDADGNYVINIPSGEDLKGGETLPVTATDKDGNKSEPATTVVTDTTAPTVPTVNP 1051
+G A+ NI SG T ++A + N S AT + P
Sbjct: 585 KKNGVAQANVPVSFNIVSG-------TAVLSANSANTNGSGKATVTLKSDK----PGQVV 633

Query: 1052 VTSDDKTITGKAEPGSTVTVTFPDGNTASGTT--------DEDGNYTITIPTNEDLKGGE 1103
V++ + V F D AS T +G IT T + +KG +
Sbjct: 634 VSAK---TAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK 689

Query: 1104 ALPVTSTDKAGNTSAPATTTVTDTTAPTAPSVNPVTSDD-------TQITGKAEPGSTVT 1156
PV++ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 1157 VTFPDGTKASGTTDADGNYVIDIPANEDLKGGETLPVTATDKAGNQSGETTTTVTDTTAP 1216
V F D + + LP + T
Sbjct: 748 VEFFTTLTI------DDGNIEIVGTGVK----GKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 1217 TAPSVNPVTSDDKTITGKAEPGSTVTVTFPDGTTTTGTADQDGNYVI 1263
P++ V + +T K + +T++V D T T T + ++
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 40.4 bits (94), Expect = 5e-05
Identities = 66/368 (17%), Positives = 118/368 (32%), Gaps = 28/368 (7%)

Query: 216 GTTQVTTADASGNYTVNIPA-NEDFTGGETIKASAKDAAGNKSVDSNVTVTDTTAPNQPT 274
G Q + + ++ +Y +PA + + + A A D GN S +NV +T T N
Sbjct: 497 GQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSS--NNVLLTITVLSNGQV 554

Query: 275 VNQVTSEDKTI-TGKAEPNSTVTVTFPDGTKVQAITATDGSYRVAVPTNIDLV-GGETLG 332
V+QV D T A+ + T +T+ A +G + VP + ++V G L
Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITY------TATVKKNGVAQANVPVSFNIVSGTAVLS 608

Query: 333 VTS--TDKAGNTSTAANTTVVDVTAPKEPVINDVTSEDKTITGTSEPNSTVTVTFPDGTK 390
S T+ +G + + ++ + + ++T K
Sbjct: 609 ANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV-DQTKASITEIKADK 667

Query: 391 ASATADASGNYTIGIPDSEDLKGDEELSVVATDAAGNVSVDAGTTVLDKTPPEVPTINPV 450
+A A+ T + + K V T G +S T + T
Sbjct: 668 TTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTP 727

Query: 451 TSEDKT--ITGKAEPNSTVTVTF-PDGTTANATTDGDGNYTIDIPANEDLRGGEALPVTS 507
+ ++ A V F T + + G LP
Sbjct: 728 GKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGV-----------KGKLPTVW 776

Query: 508 TDGAGNQSGAATTTVTDTTGPTVPTINPVTSEDTTITGHAEPGSTVTVTFPDGNTATGTT 567
A+ T P I V + +T + +T++V D TAT T
Sbjct: 777 LQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTI 836

Query: 568 DADGNYVI 575
+ ++
Sbjct: 837 ATPNSLIV 844



Score = 40.1 bits (93), Expect = 7e-05
Identities = 66/347 (19%), Positives = 116/347 (33%), Gaps = 45/347 (12%)

Query: 417 LSVVATDAAGNVSVDAGTTVLDKTPPEVPTINPVTSEDKTITGKAEPNSTVTVTFPDGTT 476
++ A D GN S + T+ + +V VT T A+ + T +T+
Sbjct: 527 VTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITY----- 580

Query: 477 ANATTDGDGNYTIDIPANEDLRGGEALPVTSTDGAGNQSGAATTTVTDTTGPTVPTINPV 536
AT +G ++P + ++ G A+ ++ N SG AT T+ V
Sbjct: 581 -TATVKKNGVAQANVPVSFNIVSGTAVL-SANSANTNGSGKATVTLKSDKPGQVVVSAKT 638

Query: 537 TSEDTTITGHAEPGSTVTVTFPDGNTATGTT--------DADGNYVINIPTDEDLKGGEE 588
+ + +A V F D A+ T A+G I T + +KG +
Sbjct: 639 AEMTSALNANA-------VIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK- 689

Query: 589 LPVTSTDKAGNKSDVATTEVTDTTSPEAPTVNPVTSED-------TTITGKAEPNSTVTV 641
PV++ + + + T+ T +TS ++ A V
Sbjct: 690 -PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748

Query: 642 TF-PDGTTATGNTDADGNYVIDIPSNEDLKGGETLPVTSTDKAGNTSQPASTVVTDTTAP 700
F T GN + G V LP + + T
Sbjct: 749 EFFTTLTIDDGNIEIVGTGV-----------KGKLPTVWLQYGQVNLKASGGNGKYTWRS 797

Query: 701 TVPSVNPVSSEDKTVTGKAEPGSTVTVTFPDGTTASGTTDADGNYTI 747
P++ V + VT K + +T++V D TA+ T + +
Sbjct: 798 ANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 36.2 bits (83), Expect = 0.001
Identities = 54/336 (16%), Positives = 100/336 (29%), Gaps = 21/336 (6%)

Query: 330 TLGVTSTDKAGNTSTAANTTVVDVTAPKEPVINDVTSEDKTITGTSEPNS---TVTVTFP 386
+ + D+ GN+S T+ ++ + VT T + T T T
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVK 585

Query: 387 DGTKASATADASGNYTIGIPDSEDLKGDEELSVVATDAAGNVSVDAGTTVLDKTPPEVPT 446
A A S N G + T+ +G +V + + T
Sbjct: 586 KNGVAQANVPVSFNIVSGT-------AVLSANSANTNGSGKATVTLKSDKPGQVVVSAKT 638

Query: 447 INPVTSED-KTITGKAEPNSTVTVTFPDGTTANATTDGDGNYTIDIPANEDLRGGEALPV 505
++ + + + +++T D TTA A YT+ + + + +
Sbjct: 639 AEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTF 698

Query: 506 TSTDGAGNQSGAATTTVTDTTGPTVPTINPVTSEDTTITGHAEPGSTVTVTFPDGNTATG 565
T+T G + S T T T + ++ A V F T
Sbjct: 699 TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEF----FTTL 754

Query: 566 TTDADGNYVINIPTDEDLKGGEELPVTSTDKAGNKSDVATTEVTDTTSPEAPTVNPVTSE 625
T D ++ L P + T P + V +
Sbjct: 755 TIDDGNIEIVGTGVKGKL------PTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDAS 808

Query: 626 DTTITGKAEPNSTVTVTFPDGTTATGNTDADGNYVI 661
+T K + +T++V D TAT + ++
Sbjct: 809 SGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 35.0 bits (80), Expect = 0.002
Identities = 56/348 (16%), Positives = 110/348 (31%), Gaps = 45/348 (12%)

Query: 674 TLPVTSTDKAGNTSQPASTVVTDTTAPTVPSVNPVSSEDKTVTGKAEPGSTVTVTFPDGT 733
+ + D+ GN+S +T + V V+ T A+ T +T+
Sbjct: 526 KVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTS-AKADGTEAITYTATV 584

Query: 734 TASGTTDADGNYTIDIPANEDLKGGETLPVTATDKDGNKSEEATTTVSDKTAPEAPTVNP 793
+G A+ + +I + + + T+ G + + + A T
Sbjct: 585 KKNGVAQANVPVSFNIVSGTAVLSANS---ANTNGSGKATVTLKSDKPGQVVVSAKTAEM 641

Query: 794 VTSDDTQITGKAEPNSTVTVTFPDGHTASGTT--------DADGNYVINIPSSEDLKGGE 845
++ + V F D AS T A+G I + + +KG +
Sbjct: 642 TSALNAN-----------AVIFVDQTKASITEIKADKTTAVANGQDAITY-TVKVMKGDK 689

Query: 846 TLPVTATDKAGNTSEQASTVVTDTTAPTVPSVNPVTSDD-------TQITGKAEPGSTVT 898
PV+ + T+ + T+ T + +TS +++ A
Sbjct: 690 --PVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPE 747

Query: 899 VTF-PDGTTATGTTDADGNYTIDIPANEDLKGGETLPVTATDKDGNKSEPATTVVTDTTA 957
V F T G + G LP + + T
Sbjct: 748 VEFFTTLTIDDGNIEIVGTGV-----------KGKLPTVWLQYGQVNLKASGGNGKYTWR 796

Query: 958 PTVPSVNPVTSDDTQITGKAEPGSTVTVTFPDGNTASGTTDADGNYVI 1005
P++ V + Q+T K + +T++V D TA+ T + ++
Sbjct: 797 SANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIV 844



Score = 33.5 bits (76), Expect = 0.007
Identities = 56/344 (16%), Positives = 100/344 (29%), Gaps = 30/344 (8%)

Query: 56 NSDGTFTVTIPKSAAGQYTIAIDAPNYDNDETN-----TFNIVDNTIVPAPLVDPVDDND 110
NS +TI + GQ + ++ D+T+ T I V V +
Sbjct: 537 NSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPV 596

Query: 111 TTIGVHGTAGSTVTVKYSNNNVIGTVTLGANSTTGTLTLSK------PLAAGTQLTSTAT 164
+ V GTA + +N + TVTL ++ + +K L A + T
Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656

Query: 165 KNGKTSAVSPTVTVTDATAPDAPVINPVTSDDTTVTGKAEPNSTVTVTFPDGTTQVTTAD 224
K T + T A DA E T T+ +T+ T +
Sbjct: 657 KASITE-IKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTN 715

Query: 225 ASGNYTVNIPANEDFTGGETIKASAKDAAGNKSVDSNVTVTDTTAPNQPTVNQVTSEDKT 284
G V + T K+ + +VD + +
Sbjct: 716 --GYAKVTL------TSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTG 767

Query: 285 ITGKAEPNSTVTVTFPDGTKVQAITATDGSYR-VAVPTNIDLVGGETLGVTSTDKAGNTS 343
+ G TV G + +G Y + I V + VT +K T
Sbjct: 768 VKG-----KLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTI 822

Query: 344 TAANTTVVDVT----APKEPVINDVTSEDKTITGTSEPNSTVTV 383
+ ++ T P ++ +++ + +
Sbjct: 823 SVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGK 866


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11220IGASERPTASE320.003 IgA-specific serine endopeptidase (S6) signature.
		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

Length = 1541

Score = 32.0 bits (72), Expect = 0.003
Identities = 32/214 (14%), Positives = 75/214 (35%)

Query: 77 STEDQATDKATTNASEEASNADQTTATTQDTSQTEKSNAEETQSTEQANTEKASSNQTTK 136
+T + T+ N+ +E+ ++ +T+ + A+E +S +ANT+ Q+
Sbjct: 1031 ATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS 1090

Query: 137 DSSNIEQDTINKTNDKPSTTDKTATTQDKQTTNNKTVNTKENQTNSVSQEKQTSDKTSTD 196
++ + +T T+ Q T Q S + + Q D
Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150

Query: 197 KTPVKATSNKTTPTTDKTTTKKVTDKKSDKETAQKATDKTSTDKATTKSTDKASANKKAI 256
T T TT T + ++ ++T + + + A +
Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210

Query: 257 SNKKTTAQPKATTKKSTKAETTELSKKLAQSKNK 290
N +++ +PK ++S ++ + S ++
Sbjct: 1211 VNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244


38EL082_RS11735EL082_RS11775N        Y        NPathogenicity Island (unbiased-composition)
LocusTagDNBiasCDNBias%GCBiasProduct
EL082_RS11735-112-0.604640YSIRK-type signal peptide-containing protein
EL082_RS11740-112-0.316389hypothetical protein
EL082_RS11745-112-1.205547SDR family NAD(P)-dependent oxidoreductase
EL082_RS11750-113-1.618245hypothetical protein
EL082_RS11755-113-1.867724short chain dehydrogenase
EL082_RS11760015-2.837676DJ-1/PfpI family protein
EL082_RS11770014-2.083621CPBP family intramembrane metalloprotease
EL082_RS11775217-1.667943aminoacyltransferase
ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11740GPOSANCHOR519e-09 Gram-positive coccus surface protein anchor signature.
		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

Length = 539

Score = 51.2 bits (122), Expect = 9e-09
Identities = 30/309 (9%), Positives = 96/309 (31%), Gaps = 15/309 (4%)

Query: 1 MKNNNSKRQFSIRKFTIGVVSIVAGITF----FVSEHDVQAAEQQSSHLSQESVLSHSKP 56
M NN+ R +S+RK G S+ +T V + +A ++ + K
Sbjct: 1 MTKNNTNRHYSLRKLKTGTASVAVALTVLGAGLVVNTNEVSAV-----ATRSQTDTLEKV 55

Query: 57 SDQDANVFSKESEIDKNINKV-DDAQSYSQQNEQQSSKAENKEIENSTQAEQVEKQEQPA 115
++ + + + + + + ++ N++ + + N + + + + ++
Sbjct: 56 QERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKAS-- 113

Query: 116 SNQTANHSSKEPSINNQESHNKQQPSDDKTPNTEPEKIEKVDNHKRIQ---DQYQDKNKK 172
Q + + + N K E EK ++ + + +
Sbjct: 114 KIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 173

Query: 173 VDNKQSNNSQLNQKEHPNSSNNKQQKQRLDVKPQKDNQQLQSRNDVKEKLDNQPIEQKDT 232
K + ++ + D+ ++++ K L + + +
Sbjct: 174 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 233

Query: 233 KQQSNNKSKDNTTSVKSHSQQHKPHSLKTQSHSTPGQKVNTNISTKPTQQQTTNQNIKPK 292
+ + N S ++ +K+ + + + + + +T
Sbjct: 234 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 293

Query: 293 NTDEATIKS 301
++A ++
Sbjct: 294 EAEKADLEH 302



Score = 33.9 bits (77), Expect = 0.002
Identities = 22/221 (9%), Positives = 63/221 (28%), Gaps = 19/221 (8%)

Query: 36 QAAEQQSSHLSQESVLSHSKPSDQDANVFSKESEIDKNINKVDDAQSYSQQ--------- 86
++ S+ ++ + S++ + + E+ ++ A ++S
Sbjct: 88 DELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLE 147

Query: 87 NEQQSSKAENK-------EIENSTQAEQVEKQEQPASNQTANHSSKEPSINNQESHNKQQ 139
E+ + A N + A+ + + A E + + N
Sbjct: 148 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 207

Query: 140 PSDDKTPNTEPEKIEKVDNHKRIQ---DQYQDKNKKVDNKQSNNSQLNQKEHPNSSNNKQ 196
K E EK ++ + + + K + ++
Sbjct: 208 ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 267

Query: 197 QKQRLDVKPQKDNQQLQSRNDVKEKLDNQPIEQKDTKQQSN 237
+ D+ ++++ K L+ + + + Q N
Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLN 308


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11750DHBDHDRGNASE547e-11 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase sig...
		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

signature.
Length = 261

Score = 53.9 bits (129), Expect = 7e-11
Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 11/191 (5%)

Query: 5 VLITGANKGIGFETAKQLGDKGWTILLGARNEERGRAAVKTLENKGITAEWIQIDLNNID 64
ITGA +GIG A+ L +G I N E+ V +L+ + AE D+ +
Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70

Query: 65 TIHAAADYIATQHSDLKALINNAGISGNMNASPLD-VELDELRELAEVNFFGNFEMIK-T 122
I I + + L+N AG+ + + + +E VN G F +
Sbjct: 71 AIDEITARIEREMGPIDILVNVAGV---LRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127

Query: 123 FTPILAKNHGRILNLTIPLNPNSF--FHPFSYIATKSPLNSMIKLFGRHFKKNKIPVEIF 180
++ + G I +T+ NP +Y ++K+ K G + I I
Sbjct: 128 SKYMMDRRSGSI--VTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI- 184

Query: 181 GVMPGGITTDL 191
V PG TD+
Sbjct: 185 -VSPGSTETDM 194


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11755PF07520260.036 Virulence protein SrfB
		>PF07520#Virulence protein SrfB

Length = 1041

Score = 26.1 bits (57), Expect = 0.036
Identities = 16/56 (28%), Positives = 23/56 (41%), Gaps = 10/56 (17%)

Query: 38 EELGIDDPTDWVLCRSDE----DND------VLLAFEFFRSDEAKDNHYSKPSTED 83
EEL P+ W R+ E D + V +A + SD+ + HY P D
Sbjct: 117 EELYDPGPSSWARLRTVELPQPDPETGHTHRVQIALDTALSDQDQSAHYVAPERAD 172


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11760NUCEPIMERASE372e-05 Nucleotide sugar epimerase signature.
		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

Length = 334

Score = 37.5 bits (87), Expect = 2e-05
Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 25/121 (20%)

Query: 1 MKVIVIDASGTIGSKVAEKLKENHHEVI------------------EVGSQSGD--YQLD 40
MK +V A+G IG V+++L E H+V+ E+ +Q G +++D
Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60

Query: 41 ITSPEQIEKMYKDIDNIDAVVSATGGATFKALSEISLEENNVAIQSKLLGQINLVLIGQH 100
+ E + ++ + V + + SLE + S L G +N++ +H
Sbjct: 61 LADREGMTDLFASGH-FERVFISPHRLAVRY----SLENPHAYADSNLTGFLNILEGCRH 115

Query: 101 Y 101

Sbjct: 116 N 116


ORFs having significant similarity with Known Virulence factors
LocusTagHitsScoreE-valueComments
EL082_RS11775DPTHRIATOXIN310.009 Diphtheria toxin signature.
		>DPTHRIATOXIN#Diphtheria toxin signature.

Length = 567

Score = 31.3 bits (70), Expect = 0.009
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 241 LSYINLD-DYKNQLIKKSSEIAKDIENTKDKLSEHPNSKKSKNKLKQLEQQWNSNEKKIT 299
LS INLD D K E K+ K+K+SE PN S+ K KQ ++++ +
Sbjct: 231 LSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHP 290

Query: 300 ETQDIIQTDGHVIDLAAALYIA 321
E ++ G A A Y A
Sbjct: 291 ELSELKTVTGTNPVFAGANYAA 312



 
Contact Sachin Pundhir for Bugs/Comments.
For best view 1024 x 768 resolution & IE 6.0 or above recommended.