>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 1e-05 Identities = 59/319 (18%), Positives = 106/319 (33%), Gaps = 29/319 (9%) Query: 31 GYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDI 90 G ++ ++ L L + + A + LL L + G +SD+ GRR + L+ + Sbjct: 22 GLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFAC-APVLGALSDRFGRRPVLLVSL 80 Query: 91 IAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAM 150 V A M + + +L + ++ + GA +A + I + + +RA F++A Sbjct: 81 AGAAV-DYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSAC 139 Query: 151 WYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECE 210 + G ++G + + AA+ L L G F LPES + Sbjct: 140 FGFGMVAGPVLGGLMGGFSPHAPFFAA-AALNGLNFLTGCFLLPESHK------------ 186 Query: 211 EMMIKLFGEPVAFEEEQPQQ-TRFRDLFNRRHFPFVLFVA-AIWTCQVIPMFAIYTFGPQ 268 GE E FR ++ V + +P FG Sbjct: 187 -------GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGED 239 Query: 269 IVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGL 328 +G + A ++ SL + P L G R L+ +L Sbjct: 240 RFHWDATTIGISLAAFGILHSLAQAMITGPVAARL---GERRALMLGMIADGTGYILLAF 296 Query: 329 IPDMGIWLVVMAFAVYAFF 347 W+ + A Sbjct: 297 ATR--GWMAFPIMVLLASG 313
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 29.2 bits (65), Expect = 0.020 Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 18/120 (15%) Query: 188 IAEELGISRAQFD-----QFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLG 242 EEL R FD F+ + QQQ G G QQAQ T ++A Sbjct: 310 TLEEL---RDSFDGYINNAFVNQIHLNFVMPPQAQQQQGQGQQQQAQ--ATAQEAVAAAA 364 Query: 243 VKPTDDATTIKRAYRKLMS-EHHPDKLVAKGLPPEMMEMAKQKAQEIQ-QAYELIKQQKG 300 V+ + + I + Y+ L+ + H G+ M ++A Q+ ++ + Q KQQ+G Sbjct: 365 VRLLNGSDQIAQLYKDLVKLQRH------AGIRKAMEKLAAQQEEDAKNQGKGDCKQQQG 418
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 26.3 bits (58), Expect = 0.047 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 2 SKYIYILLSF-LVLFFIFFYAYISLMSKE 29 IYI+ F L++FF FFY IS +E Sbjct: 314 DHPIYIVTYFLLIVFFAFFYVAISFNPEE 342
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.005 Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 5/80 (6%) Query: 4 RRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWVAVWQDS-YLWHVVRFSFWQ 62 R GWL + L V A +W+ A ++W+ ++ Sbjct: 60 RSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVAN----TSIWRLLAFINTKPVAFTLP 115 Query: 63 AFLSALLSVVPAIFLARALY 82 LS + +VV F+ LY Sbjct: 116 LALSIIFNVVVVTFMWSLLY 135
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 184 bits (467), Expect = 1e-52 Identities = 97/287 (33%), Positives = 136/287 (47%), Gaps = 27/287 (9%) Query: 313 ALAGSTATTRVRFFWGTDIHGKPQVYGVHTGEGTPY-ENVRVANMQWNEQTQRYEFT--- 368 A+A ++ T + + G V + +G + V V +N T YE T Sbjct: 345 AVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPS 404 Query: 369 PAHDVDGPLITWTPENPEHGYVPGHTGN--DRPPLEQPTILVTPIPDGTDTYTTPPFPVP 426 + ++TWTP +P P T +P +TP+ T +P Sbjct: 405 TTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPV-----KATPETYPGV 459 Query: 427 DPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSNNGNG 486 D I+ FPA SGIKPIYV + DPR +PG TG+G P+ WL ++ G G Sbjct: 460 ITLP-EDLIIGFPADSGIKPIYVMFR-DPRDVPGAATGKGQPV--SGNWLG--AASQGEG 513 Query: 487 APIPAHIADKLRGREFKTFDEFREALWLEVSQDPELIAQFSSGNQTRIKQGLTAKAPIDG 546 APIP+ IADKLRG+ FK + +FRE W+ V+ DPEL QF+ G+ ++ G Sbjct: 514 APIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSLAVMRDGGAPYVR--- 570 Query: 547 WYYGPKEIV---KKFQIHHRVAVEYGGSVYDIDNLRIVTPRLHDEIH 590 E K +IHH+V V GG VY++ NL VTP+ H EIH Sbjct: 571 ----ESEQAGGRIKIEIHHKVRVADGGGVYNMGNLVAVTPKRHIEIH 613
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 26.0 bits (57), Expect = 0.018 Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 1 MYNFKDEIEDYTEREFIELLGEFTNPTGDNAQLK 34 Y+ K+ I+D ++F + L EFT T N +LK Sbjct: 88 QYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLK 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.002 Identities = 42/281 (14%), Positives = 90/281 (32%), Gaps = 32/281 (11%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA--------EEKKEAAPAAA-----PAAAAAKDVNVPDIGSDEVEVTEILVKVG-DKV 131 Q+ + + + + P + ++ +EV L+K Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 132 EAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSLIMVFEVAGEAGAVAPAAK 191 + ++ + DK E A + ++ +K + A + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK-QAIAKHAVLEQ 257 Query: 192 QEAAPAAAPASAAGVKEVNVPDIGGDEV-------------EVTEVMVKVGDKVAA-EQS 237 + A ++ + E+ + + + D + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 238 LITVEGDKASMEVPAPFAGVVKELKVN-VGDKVKTGSLIMI 277 L E + + + AP + V++LKV+ G V T +M+ Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.035 Identities = 20/95 (21%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G +++ GA A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE-ADTL 137 Query: 290 AKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAEND 324 Q + A + + + + E D Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.018 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 22/100 (22%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLL- 164 V +E G L + V L AV GL P +V + D++G LL Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSG-HLLT 220 Query: 165 -SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 221 QSNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 805 bits (2081), Expect = 0.0 Identities = 263/869 (30%), Positives = 428/869 (49%), Gaps = 40/869 (4%) Query: 12 IATFCALLYSNSALCAELVEYDHTFLMGKDASNIDLSRYTEGNPTLPGIYDVSVYVNDQP 71 + CA AE + ++ FL + DLSR+ G PG Y V +Y+N+ Sbjct: 30 LFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 72 IMSQSIAFAVIEGKKNAQACITQKNLLQFHISSPDKNSEKAILLKRDDDLGDCLNLAEMI 131 + ++ + F + ++ C+T+ L +++ + + C+ L MI Sbjct: 89 MATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLL------ADDACVPLTSMI 142 Query: 132 PQSSIRYDVNDQRLDIDVPQAWIMKNYQNYVDPSLWENGINAAMLSYNLNGYHSESP-GR 190 ++ + DV QRL++ +PQA++ + Y+ P LW+ GINA +L+YN +G ++ G Sbjct: 143 HDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGG 202 Query: 191 TNDSIYAAFNGGINLGAWRLRASGNYNWITNVHS-----DYDFQNRYLQRDLASLRSQLV 245 + Y G+N+GAWRLR + +++ ++ S + N +L+RD+ LRS+L Sbjct: 203 NSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262 Query: 246 IGESYTTGETFDSVRIRGIRLYSDSRMLPPVLASFAPIIHGVANTNAKVTVMQNGYKIYE 305 +G+ YT G+ FD + RG +L SD MLP FAP+IHG+A A+VT+ QNGY IY Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322 Query: 306 TTVPPGAFAIDDLSPSGYGSDLIVTIEEADGTKRTFSQPFSSVVQMLRPGVGRWDISAGQ 365 +TVPPG F I+D+ +G DL VTI+EADG+ + F+ P+SSV + R G R+ I+AG+ Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382 Query: 366 VLKD-SIQDEPNLFQASYYYGLNNYLTGYTGIQLTDNNYTAGLLGLGMNT-PVGAFSVDV 423 + Q++P FQ++ +GL T Y G QL D Y A G+G N +GA SVD+ Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVDM 441 Query: 424 THSNVSIPDDKTYQGQSYRISWNKLFENTSTSLNIAAYRYSTQHYLGLNDALTLIDEVEH 483 T +N ++PDD + GQS R +NK + T++ + YRYST Y D + Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501 Query: 484 PE-----QDLEPKSMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASGQ 535 E ++PK Y+ + ++ +++ Q L + YLSGS YW + Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTSN 557 Query: 536 NSTNYSIGYSNSASWGSYSISAQRSLNE-DGQTDDSIYLSFTIPIENLLGTEHRSS-GFQ 593 + G + + ++++S + N D + L+ IP + L ++ +S Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 594 SIDTQLNSDFKGNNQLNISSSGYSDT-NRISYSVNTGYMMNKSSDDLSYIGGYASYESPW 652 S ++ D G G N +SYSV TGY + S +Y + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 653 GTLSGSASASSDNSRQFSLNTDGGFVLHSGGLTFSNDSFSDSDTLAVIQAPGAKGARINY 712 G + S S D +Q GG + H+ G+T +DT+ +++APGAK A++ Sbjct: 678 GNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVEN 733 Query: 713 GNST-VDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSTVAVPRQGAVVFADFETV 771 D GY V + Y ENR+ALD N L ++V+L + VP +GA+V A+F+ Sbjct: 734 QTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKAR 793 Query: 772 QGQSAIMNIVRSDGKNIPFAADIYDEQNNIIGNVGQGGQAFVRGIGQEGNIRITWIEEGK 831 G +M + + K +PF A + E + G V GQ ++ G+ G +++ W EE Sbjct: 794 VGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 832 PVSCFAHYQQNTTSEKIAQSIILNGLRCQ 860 C A+YQ S++ Q + C+ Sbjct: 853 A-HCVANYQLPPESQQ--QLLTQLSAECR 878
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 509 bits (1313), Expect = 0.0 Identities = 293/296 (98%), Positives = 294/296 (99%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAA IDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYEDFIRSMKPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLA YEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRILDNAIGGKA 296 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVR+LDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 5e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 31.6 bits (71), Expect = 0.012 Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 10/107 (9%) Query: 519 TETIGNDQKITVGLG--QTVNVGSKKEGGHDQKVTVANDQHLTIKNDRHKVVNNNQTSKV 576 T+T G D +T G G QT GS G+ T D L + QT+ Sbjct: 359 TQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAG------YGSTQTAGE 412 Query: 577 TGTDTEEVVKKQSIKIGDNYELKVEHGTNIISGDSIELICGQGESGT 623 T T Q+ + G + L +G+ +GD LI G G + T Sbjct: 413 ESTQTAGYGSTQTAQKGSD--LTAGYGSTGTAGDDSSLIAGYGSTQT 457
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 548 bits (1413), Expect = 0.0 Identities = 231/384 (60%), Positives = 267/384 (69%), Gaps = 34/384 (8%) Query: 3 MKKSTLALVVMGIVASVSVQAAEIYNKDGNKLDVYGKVKAMHYMSDNDSKDGDQSYIRFG 62 MK+ LALV+ ++A+ + AAEIYNKDGNKLD+YGKV +HY SD+ SKDGDQ+Y+R G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 63 FKGETQINVQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALY 122 FKGETQIN QLTGYG+WE N E + A TRLAFAGLK+ D GSFDYGRN G LY Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 123 DVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNEN-- 180 DVE WTDM PEFGGDS DN+MT RA+G+ATYRNTDFFG++DGLN LQYQGKNE+ Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 181 --------------RDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSR-- 224 D++ NGDGFG S TYD G F+ AYT SDRTNEQ Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDI-GMGFSAGAAYTTSDRTNEQVNAGGTI 239 Query: 225 GTGKRAEAWATGLKYDANNIYLATFYSETRKMTP-------ISGGFANKTQNFEAVAQYQ 277 G +A+AW GLKYDANNIYLAT YSETR MTP GG ANKTQNFE AQYQ Sbjct: 240 AGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQ 299 Query: 278 FDFGLRPSLGYVLSKGKDIE----GIGDEDLVNYVDVGATYYFNKNMSAFVDYKINQLDS 333 FDFGLRP++ +++SKGKD+ D+DLV Y DVGATYYFNKN S +VDYKIN LD Sbjct: 300 FDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDD 359 Query: 334 DNKL----NINNDDIVAVGMTYQF 353 D+ I+ DDIVA+GM YQF Sbjct: 360 DDPFYKDAGISTDDIVALGMVYQF 383
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 119 DTLRALLDNNI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAA-DVACRAG 228 D G + + +++V +++ + G M K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAA 235 IIA Sbjct: 290 ERAIIAH 296 Score = 30.2 bits (68), Expect = 0.013 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAAGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 29.3 bits (65), Expect = 0.048 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 60 VDKIAQQ-KAKTEKQNQRAQAAAARAQARQQQQIAARKEKAEL 101 V++IAQQ K E Q+A + A+AQ R + Q A R+E+ +L Sbjct: 318 VEQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQL 360
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 615 bits (1586), Expect = 0.0 Identities = 267/886 (30%), Positives = 407/886 (45%), Gaps = 123/886 (13%) Query: 42 SLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DK 99 +L ++ L A+ V + YQ +RDFAENKG+F GATN+ + + + +G + Sbjct: 12 ALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNG 71 Query: 100 APMVDFSSVNVSSNPGVATLINPQYIASVKH-NKGYQSVSFG------------------ 140 PM+DFS V + +ATLINPQY+ VKH + G + FG Sbjct: 72 IPMIDFSVV--DVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVS 129 Query: 141 DGQNSYHIVDRNEHSSS-----------------DLHTPRLDKLVTEVAPATVTSSST-- 181 +N Y V++NE+ + D + PRLDK VTEVAP +++S+ Sbjct: 130 SEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDA 189 Query: 182 ADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYH--------- 232 + +KY AF R GSGSQ+I + + + Y Sbjct: 190 GTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYK 249 Query: 233 --GSDGIQLYMGGNIHDHSI---------LPSFGEAGDSGSPLFGWNTAKGQWELVGVYS 281 + + G + +HS L ++ GDSGSPLF ++ KG+W +G Y Sbjct: 250 VNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYD 309 Query: 282 ---GVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPLQWKFDSSTGTGSLKQGS 338 G + +++ F + ++D+ + + + + S+ T ++ G Sbjct: 310 FWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSK-----TDYSWSSNGKTSTITGGE 364 Query: 339 DEYAMHGQKGSDL-NAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVT-TSNGSTWT 396 + G D N GK++TF G +G + L N++ QGAG L F DY V TS+ +TW Sbjct: 365 KSLNVDLADGKDKPNHGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWK 423 Query: 397 GAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSS 456 GAG+ V + +V W+V+ + D L KIG+GTL+V+GTG N+G LKVGDGTV+L QQ + S Sbjct: 424 GAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGS 483 Query: 457 GHVQAFSSVNIASGRPTVVLADNQQVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGAT 516 G AF+SV I SGR T+VL D++QV+P++I +G+RGG LD+NGN LTF + D GA Sbjct: 484 GQ-HAFASVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGAR 542 Query: 517 LGNS-SDKTANITLD---YQTRPANVKV---------NEWSSSNRGTVGSLYIYNNPYTH 563 L N +NIT+ T P + N ++ G LY+ YT Sbjct: 543 LVNHNMTNASNITITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYT- 601 Query: 564 TVDYFILK--TSSYGWFP-TGQVSNEHWEYVGHDQNSAQALLANRINNK------GYLY- 613 Y+ L+ S+ P SNE+W Y+G + A+ + N INN+ GY Sbjct: 602 ---YYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGE 658 Query: 614 -HGKLLGNINFSNKATPGTTGALVMDGSANMSGTFTQENGRLTIQGHPVIHASTSQSIAN 672 GK GN+N + K ++ G N++G T E G L + G P HA + IA Sbjct: 659 EEGKNNGNLNVTFKGKSE-QNRFLLTGGTNLNGDLTVEKGTLFLSGRPTPHA---RDIAG 714 Query: 673 TVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLK-DTDFGLGRN-ATLNTTIQADNSS- 729 S+ D +DDW NR F ++ + + GRN A + + I A N + Sbjct: 715 ISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQ 774 Query: 730 ----VTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQS--VLNINE 783 GD+ G T T ++ + A + + G VNL + VL Sbjct: 775 VHIGYKTGDTVCVRSDYTGYVTC-TTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKAN 833 Query: 784 IFNGGIQANNSTVNISSDS-------AVLENSTLTSTALNLNKGAN 822 +F NS V ++ +S + + L + ++LN N Sbjct: 834 LFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADN 879 Score = 53.5 bits (128), Expect = 5e-09 Identities = 65/329 (19%), Positives = 121/329 (36%), Gaps = 54/329 (16%) Query: 760 KDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISSDSAVLENSTLTSTALNLNK 819 K +D++ N +++N+ + N F NN +N++ +N L + NLN Sbjct: 631 KTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNG 690 Query: 820 GANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSW----------NLKG 869 V F+S P + ++S + W N+ G Sbjct: 691 DLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTG 750 Query: 870 DDARLNVGPYSMLSGNINVQDKGTVTLG--------------GEGELSPDLTLQNQMLYS 915 + + + + ++ NI +K V +G G + D L ++ L S Sbjct: 751 NASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTD-KLSDKALNS 809 Query: 916 LFN-----------------GYRNTWSGSLNAPDATVSMT-DTQWSMNGNSTAGNMKLNR 957 G N + + ++ V +T ++ W + GNS + L Sbjct: 810 FNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLAN 869 Query: 958 TIVGFNGGTSS-----FTTLTTDNLDAVQSAFVMRTDL--NKADKLVINKSATGHDNSIW 1010 + N +S + TLT ++L +F TDL + DK+V+ KSATG+ Sbjct: 870 GHIHLNSADNSNNVTKYNTLTVNSLSG-NGSFYYLTDLSNKQGDKVVVTKSATGNFTLQV 928 Query: 1011 VNFLKKPSDKDTLDIPLVSAPEATADNLF 1039 + +P+ ++ L A +A D+L Sbjct: 929 ADKTGEPNHN---ELTLFDASKAQRDHLN 954
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 62.6 bits (152), Expect = 5e-12 Identities = 29/247 (11%), Positives = 73/247 (29%), Gaps = 23/247 (9%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSS 546 L + + T +S + Y + +Q+ + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFDTGLEN---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G ++ + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLD 718 + + + Sbjct: 762 TNTLADN 768
>INTIMIN#Intimin signature. Length = 939 Score = 549 bits (1416), Expect = e-178 Identities = 234/832 (28%), Positives = 356/832 (42%), Gaps = 78/832 (9%) Query: 41 PVMAARAQHAVQPRLSMENTTVTADNNVEKNVASLAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT N + + AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKNFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L NF SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F + M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFF-LPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRER 335 +P A T VNYTP+PL+T+ ++ G END + ++ Y+ +P +Q++ + E Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427 Query: 336 RMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLKNVQ 395 R L+GSRYDLV+RNNNI+LEY+K +++ + +P I G T + L+V K+ +GL + Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486 Query: 396 WEAPSLLAAGGKITGQG----NQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTEV 451 W+ +L + GG+I G +Q LPAY G N Y ++A AYD GN+S V + Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546 Query: 452 VISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLR----DAEGQPVTGMKDQIKTE 507 + G D+ +T + A+G E +++ PV+ Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVS--------- 597 Query: 508 LTFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMSK 567 NIV+ T + + A +G + G+ ++ +M+ Sbjct: 598 ------FNIVSGTAVLSANSAN-------TNGSGKATVTLKSDK-PGQVVVSAKTAEMTS 643 Query: 568 TVTAELRATMMDVSNSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRLVP 627 + A + S VA+GQ A T T+ V PV+ + Sbjct: 644 ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF---- 698 Query: 628 QDTNGVTVGAIS--EIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP--- 682 T + + G T++ST G +V A + ++F Sbjct: 699 -TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTID 757 Query: 683 ----------LDAAHSSITLNPDK---PVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSG 729 + ++ L + GG W + + V + +L Sbjct: 758 DGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDA-SSGQVTLKE 816 Query: 730 AAAAGSTASGWTDNGDGTWTAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSN 789 + +DN T+T T L V L S+ Sbjct: 817 KGTTTISVIS-SDNQTATYTIA-----TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSS 870 Query: 790 QSKV-------SVAEDHVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTAS 834 Q+++ A + S T+ + +A SG++ + L Sbjct: 871 QNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDLVKQNP 922 Score = 73.6 bits (180), Expect = 4e-15 Identities = 75/364 (20%), Positives = 120/364 (32%), Gaps = 39/364 (10%) Query: 882 TVIAGEMSSANSTLVADNKTPTVKTTTELTFTMKDAYGNPVTGLKPDAPVFSGAASTGSE 941 V + ++ ++ AD T T + PV+ + SG A Sbjct: 557 QVGVTDFTADKTSAKADGTEAITYTAT-VKKNGVAQANVPVSFN-----IVSGTAV---- 606 Query: 942 RPSAGNWTEKGNGVYVSTLTLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDM 1001 SA + G+G TL + +A+ V+ V D +KA I ++ Sbjct: 607 -LSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITEI 663 Query: 1002 TVKVNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVD 1060 +ANGQ A IT TV V P+ QEVT T G S + T T+ G Sbjct: 664 KADKTTAVANGQDA--ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYAK 719 Query: 1061 IELMSTVAGELEIEASVKNSQKTVKVKFKADFSTGQASLEVDAA-AQKVANGKDAFTLTA 1119 + L ST G+ + A V + VK F +L +D + V G T Sbjct: 720 VTLTSTTPGKSLVSARVSDVAVDVKAPEVEFF----TTLTIDDGNIEIVGTGVKGKLPTV 775 Query: 1120 TVK-DQYGNLLPGAVVVFNLPRGVKPLADGNIMVNADKEGKAELKVVSVTAGTYEITASA 1178 ++ Q G + A+ I G+ LK GT I+ + Sbjct: 776 WLQYGQVNLKASGGNGKYTW-----RSANPAIASVDASSGQVTLK----EKGTTTISVIS 826 Query: 1179 GNDQPSNAQSVTFVADKTTATISSIEVIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVT 1238 ++Q T+ + I + D ++ N L++ Sbjct: 827 SDNQT-----ATYTIATPNSLI-VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKA 880 Query: 1239 LTAS 1242 A+ Sbjct: 881 WGAA 884 Score = 54.7 bits (131), Expect = 2e-09 Identities = 46/249 (18%), Positives = 82/249 (32%), Gaps = 24/249 (9%) Query: 1168 TAGTYEITASA----GNDQPSNAQSVTFVADKTTAT---ISSIEVIGNRAVADGKTKQTY 1220 + Y++TA A GN + ++T +++ ++ A ADG TY Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1221 KVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQAIFTATTTVAATYTLTAKV 1280 TV S + +A TN G+A T + ++AK Sbjct: 581 TATVKKNGVAQANVPVSFNIVS--GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK- 637 Query: 1281 EQADGQESTKTAESKFVADDKNAVLAASPERVDSLVADGKTTATLTVTLMSGVNPVGGTM 1340 A+ + FV K ++ ++ + VA+G+ T TV +M G PV Sbjct: 638 -TAEMTSALNANAVIFVDQTKASITEIKADK-TTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 1341 WVDIEA--PEGVTEADYQFLPSKNDHFASGKITRTFSTNKPGTYTFTFNSLTYGGYEMKP 1398 + K D +G T ++ PG + ++ ++K Sbjct: 696 VTFTTTLGKLSNSTE-------KTD--TNGYAKVTLTSTTPGKSLVS-ARVSDVAVDVKA 745 Query: 1399 VTVTINAVP 1407 V Sbjct: 746 PEVEFFTTL 754 Score = 45.8 bits (108), Expect = 1e-06 Identities = 55/368 (14%), Positives = 104/368 (28%), Gaps = 56/368 (15%) Query: 779 VTVVADALSSNQSKV---SVAEDHVKAGESTTVTLVA------KDAHGNAISGLSLSASL 829 +TV+++ +Q V + + KA + +T A +S +S Sbjct: 546 ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSG-- 603 Query: 830 TGTASEGATVSSWTEKGDGSYVAT--LTTGGKTGELRVMPLFNGQPAATEAAQLTVIAGE 887 A +S+ + +GS AT L + + A A + + Sbjct: 604 ------TAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN--ANAVIFVDQ 655 Query: 888 MSSANSTLVADNKTPTVKTTTELTFTMKDAY-GNPVTGLKPDAPVFSGAASTGSERPSAG 946 ++ + + AD T +T+T+K PV+ + +T + S Sbjct: 656 TKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV-------TFTTTLGKLSNS 708 Query: 947 NWTEKGNGVYVSTLTLGSAAGQLSVMPRVNGQN-AVAQPLVLNVAG---DASKAEIRDMT 1002 NG TLT + G+ V RV+ V P V D EI Sbjct: 709 TEKTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEI---- 763 Query: 1003 VKVNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDI 1061 + G T+ + G T ++ ++G+V + Sbjct: 764 ------VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTW---RSANPAIASVDASSGQVTL 814 Query: 1062 ELMSTVAGELEIEASVKNSQKTVKVKFKADFSTGQASLEVDAAAQKVANGKDAFTLTATV 1121 + G I ++Q + + + + Sbjct: 815 K----EKGTTTISVISSDNQ---TATYTIATPNSLIVPNMSKRVT-YNDAVNTCKNFGGK 866 Query: 1122 KDQYGNLL 1129 N L Sbjct: 867 LPSSQNEL 874
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.028 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 14 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 55 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 121 bits (305), Expect = 2e-30 Identities = 112/509 (22%), Positives = 187/509 (36%), Gaps = 73/509 (14%) Query: 324 LDINLSDSSVWKGKVSGAGDASVSLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNTGT 383 LD+ L+ + W G S+S+ N W +T +S V AL + + G Sbjct: 413 LDVALASQARWTGATRAVD--SLSIDNA-TWVMTDNSNVGALRLASDGSVDFQQPAEAGR 469 Query: 384 FA-------SQNGTLI----VDASSENTLDISGKASGDLRVY---------SAGSLDLIN 423 F + +G D + L + ASG R++ SA +L L+ Sbjct: 470 FKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQ 529 Query: 424 EQ----TAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHK----------- 468 F KD G + G Y+Y L +G + V Sbjct: 530 TPLGSAATFTLANKD------GKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGP 583 Query: 469 -----------------------ASNASSVIQAMA-AAPANVANLQADTLSARQDAVRLS 504 ++ A++ + + + +++ LS R +RL+ Sbjct: 584 QPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLN 643 Query: 505 ENDKGGVWIQYFGGKQKHTTAGNASYDLDVNGVMLGGDTRFMTEDGSWLAGVAMSSAKGD 564 D GG W + F +Q+ +D V G LG D G W G +GD Sbjct: 644 P-DAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGD 702 Query: 565 MT-TMQSKGDTEGYSFHAYLSRQYNNGIFIDTAAQFGHYSNTADVRLMNGGGTIKADFNT 623 T G T+ Y + ++G ++D + N V +G +K + T Sbjct: 703 RGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGY-AVKGKYRT 761 Query: 624 NGFGAMVKGGYTWKDGNGLFIQPYAKLSALTLEGVDYQL-NGVDVHSDSYNSVLGEAGTR 682 +G GA ++ G + +G F++P A+L+ G Y+ NG+ V + +SVLG G Sbjct: 762 HGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLE 821 Query: 683 VGYDFAVGNA-TVKPYLNLAALNEFSDGNKVRLGDESVNASIDGAAFRVGAGVQADITKN 741 VG + V+PY+ + L EF V + + G +G G+ A + + Sbjct: 822 VGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRG 881 Query: 742 MGAYASLDYTKGDDIENPLQGVVGINVTW 770 YAS +Y+KG + P G +W Sbjct: 882 HSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.4 bits (66), Expect = 0.035 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 247 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 306 W+ L L+ G +A +LR R+ + + P++ G+I Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272 Query: 307 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDWLRQHPQQHISINLE 365 AR+ +T + S +PL Q +S + ++ R D +R+ H + LE Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328 Query: 366 STVLTSEKIPQLLREMI 382 T L P ++R MI Sbjct: 329 QTAL----FPPMMRHMI 341
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3546), Expect = 0.0 Identities = 802/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 7e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQAAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.0 bits (78), Expect = 9e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQAAYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 168 RINLA 172 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 9e-05 Identities = 40/251 (15%), Positives = 78/251 (31%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALST-LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S+ ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 4e-19 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 16 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFTGVLIDLDL-- 69 K ITG + GIG A L QG H+ A P+ +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRYSGIKVSLIEP 189 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>PF09025#YopR Core Length = 143 Score = 28.4 bits (63), Expect = 0.019 Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 8/61 (13%) Query: 126 EAVLIGQLECKSMVRMCAPLGSR--------LPLHASGAGKALLYPLAEEELMSIILQTG 177 + + +LE K+M+R PLG + L G L LA EL +I G Sbjct: 68 QGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQVLIPLNG 127 Query: 178 L 178 + Sbjct: 128 M 128
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 56.3 bits (136), Expect = 1e-10 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKDGKIAAIG-------QD-----LGDAKDVMDASGLVV 51 D +I N ++ DI +KDG+IAAIG Q +G +V+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 383 bits (984), Expect = e-136 Identities = 125/310 (40%), Positives = 175/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAKNQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + + N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQGLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVAEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRRATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.030 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.1 bits (86), Expect = 9e-05 Identities = 82/394 (20%), Positives = 147/394 (37%), Gaps = 38/394 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSVRPGLLMLLSTLG---AFLAISLFGLMP 309 A IG AA L + A+ +G +A + ++L + ++ ++ Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403 + A + + +G+ + L LL L LRR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 62.7 bits (152), Expect = 2e-13 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 35/280 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQ 309 KD DA+ A PL +P V+ + + F SAM Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMH 283
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 444 bits (1142), Expect = e-161 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 365 bits (939), Expect = e-131 Identities = 111/258 (43%), Positives = 150/258 (58%), Gaps = 20/258 (7%) Query: 15 GKNVWITGAGKGIGYATALAFVEAGAKVTGFD---------------QAFTQEQYPFATE 59 GK +ITGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 60 VMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 119 DV D+A + ++ R+ E +D+LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 120 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 179 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 180 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 239 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 240 ASHITLQDIVVDGGSTLG 257 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 8e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTTP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.007 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGINAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.0 bits (62), Expect = 0.037 Identities = 18/65 (27%), Positives = 26/65 (40%) Query: 255 AMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGN 314 AM N + + Y++G+ E A ++FQ LD + F LG Q G Sbjct: 26 AMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ 85 Query: 315 IAEAI 319 AI Sbjct: 86 YDLAI 90
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 63.5 bits (154), Expect = 8e-13 Identities = 35/203 (17%), Positives = 67/203 (33%), Gaps = 10/203 (4%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + + ++ + A +E AE Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 159 AAKKAAADAKKKAEAEAAKA-----AVEAQKKAEAAAAALKK---KAEAAEAAAAEARKK 210 + +++ K + +A A A EA+ +A + +E E E ++ Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 211 AATEAAEKAKAEAEKKAAAEKAAADKKAAADKKAAEKAAAEKAAADKKA--AAEKAAADK 268 A E EKAK E EK K + ++ + AE A + E + Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN 1163 Query: 269 KAAAAKAAAEKAAAAKAAAEADD 291 A + A++ ++ + Sbjct: 1164 TTADTEQPAKETSSNVEQPVTES 1186 Score = 57.0 bits (137), Expect = 1e-10 Identities = 30/219 (13%), Positives = 82/219 (37%), Gaps = 11/219 (5%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAV 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 DKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEK 279 ++ E + + A + ++ K Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Score = 56.6 bits (136), Expect = 1e-10 Identities = 31/229 (13%), Positives = 70/229 (30%), Gaps = 9/229 (3%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAVEAQKK 185 +++ KQ + + A+ + + +E + A + A+ + VE Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 186 AEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAADKKAA 245 E E + + +++ + A Sbjct: 1185 ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244 Query: 246 EKAA--------AEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 286 A +D +A A+ A + A ++ ++ + Sbjct: 1245 STVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 53.5 bits (128), Expect = 1e-09 Identities = 34/260 (13%), Positives = 80/260 (30%), Gaps = 9/260 (3%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ + K + +E ++ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 164 AADAKKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEA 223 A+ E + E Q + A + E + + Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 224 EKKAAAEKAAADKKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAA-AKAAAEKAAA 282 E A +++K + ++ A ++ D+ A + A Sbjct: 1200 ENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNA 1259 Query: 283 AKAAAEADDIFGELSSGKNA 302 + A A F L+ GK Sbjct: 1260 VLSDARAKAQFVALNVGKAV 1279
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 298 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 357 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 358 KRGEIFG----LLGPNGAGKSTTFKMMCGL 383 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.048 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 39 YVTGLVGPDGAGKTTLMRMLAGL 61 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.8 bits (150), Expect = 8e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 83 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 142 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 143 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 197 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 198 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 255 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 256 QPGRKVLLYTDGRPNKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 309 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 310 ----DADDALRQGMPVTVQ 324 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.4 bits (177), Expect = 9e-18 Identities = 32/220 (14%), Positives = 74/220 (33%), Gaps = 29/220 (13%) Query: 13 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 71 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 72 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSK---FISR 128 IGE E + P + +RE+++ + + + + + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 129 EQLSPTAAYHLVHEQVISPLHSHLTRLIAAW---TGCDASDTRMILHTHALIGEILAFRL 185 E A + + + L I A +I+ I ++ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM--RGYISGLM---- 175 Query: 186 GKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 225 W + + + ++ ++L+ Sbjct: 176 --------ENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.026 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 255 bits (654), Expect = 1e-90 Identities = 171/171 (100%), Positives = 171/171 (100%) Query: 3 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPL 62 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPL Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPL 60 Query: 63 GVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPT 122 GVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPT Sbjct: 61 GVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPT 120 Query: 123 YKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF 173 YKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF Sbjct: 121 YKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF 171
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 23 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 72 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 73 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 132 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 133 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 188 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 189 --STARDMA------LLGKAL 201 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 39.2 bits (91), Expect = 8e-06 Identities = 30/159 (18%), Positives = 53/159 (33%), Gaps = 20/159 (12%) Query: 40 RLDKNDAAVLLVDHQAGLLSLVRDIEP--DKFKNNVLALGDLAKYFNLPTILTT---SFE 94 D N A +L+ D Q + + N+ L + +P + T S Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQN 84 Query: 95 TGPNGPLV----PELKAQFPDAPYIAR----PGNI-------NAWDNEDFVKAVKATGKK 139 L P L + + I ++ +A+ + ++ ++ G+ Sbjct: 85 PDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRD 144 Query: 140 QLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNE 178 QLII G+ + A A E F V DA F+ Sbjct: 145 QLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.1 bits (67), Expect = 0.017 Identities = 13/49 (26%), Positives = 24/49 (48%) Query: 9 GRYEVDVRPQGADGKRIRRKFKTKGEAQAFERHVLVNYHNKEWLEKPAD 57 R E D + G+DG ++ K++T G + E + + +LE A+ Sbjct: 751 SRLENDFKVAGSDGYAVKGKYRTHGVGVSLEAGRRFAHADGWFLEPQAE 799
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.017 Identities = 11/72 (15%), Positives = 26/72 (36%) Query: 11 VEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERERLTVCFHAQLKQRHATMRFEEMNDV 70 + ++ L + W D ++ RER+ +++ + E M Sbjct: 703 IPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHF 762 Query: 71 ERERLVCAIDEL 82 E+ ++ +D L Sbjct: 763 EKGVMLQTLDSL 774
>PF06872#EspG protein Length = 398 Score = 28.1 bits (62), Expect = 0.033 Identities = 23/95 (24%), Positives = 37/95 (38%), Gaps = 5/95 (5%) Query: 122 PPYMFTEEVALAAMRAHAAGESVDTRLLTDTLELTATADMPDEVRAKLHKITGLFLRDAG 181 P M T ++ A+ A S+D + +T +++ V + TG+ + Sbjct: 298 PALMLTHV-RISQASAYNAQRSLDMPNACINISITQSSEGSIHVTSH----TGVLIMAPE 352 Query: 182 DAAGALAHLQRATQLDCQAGVKKEIERLERELKPK 216 D L L T + GVK E + R LK K Sbjct: 353 DRPNQLGMLTNRTSYEVPPGVKCEPNEMARMLKAK 387
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.005 Identities = 22/173 (12%), Positives = 58/173 (33%), Gaps = 8/173 (4%) Query: 8 QVLLRAVDQASRPFKSIRTASKSLSGDIRETQKSLRELNGQASRIEGFRKTSAQLAVTGH 67 VLL+ + + ++S R Q + L+ + + Sbjct: 122 DVLLKLTALGAE---ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 68 ALEKARQEAEALATQFKNTERPTRAQAKV-LESAKRAAEDLQAKYNRLTDSVKRQQRELA 126 E+ +L + +T + + Q ++ L+ + + A+ NR + + ++ L Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 127 AVGINTRNLAHDELGLKNRISETTAQLNRQRDALARVSAQQAKLNAVKQRYQA 179 +L H + K+ + E + + L +Q ++ + + Sbjct: 239 DF----SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.9 bits (62), Expect = 0.032 Identities = 20/114 (17%), Positives = 34/114 (29%), Gaps = 11/114 (9%) Query: 50 PFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLL--------FFFITGGR 101 PF + G + G ++P +M LS G + F +I G Sbjct: 257 PFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGIL 316 Query: 102 VPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKI 155 V +GV + F + + +V+ + GL K Sbjct: 317 VDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW---FMTIIIVFVLGGLSFTKT 367
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 75.8 bits (186), Expect = 2e-18 Identities = 44/176 (25%), Positives = 70/176 (39%), Gaps = 23/176 (13%) Query: 26 TFDPQQTALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARTAGMLIIWFQ 85 DP + L++ DMQN + +D S + ANI+ G+ +++ Sbjct: 25 VPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY-- 76 Query: 86 NGWDEQYVEAGGPGSPNYHKSNALKTMRNQPLLQGKLLAKGSWDYQLVDELVPQPGDIVL 145 PGS N L G L G ++ +++ EL P+ D+VL Sbjct: 77 ---------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 146 PKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDA 201 K RYS F T L ++R G L+ TGI ++ T + F + + DA Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 2e-15 Identities = 30/165 (18%), Positives = 62/165 (37%), Gaps = 8/165 (4%) Query: 10 GKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAV 69 K + ++ IL AL FSQ G T L +IA+ AGV++ + ++F K L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 LRQILDIWLAPLKAFREDF--APLAAIKEYIRLKLEVSRDYPQASRLFCM-----EMLAG 122 ++ F PL+ ++E + LE + + L + E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 APLLMDELTGDLKALIDEKSALIAGWVKSGKL-APIDPQHLIFMI 166 ++ D + +++ L A + + ++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 30.6 bits (69), Expect = 0.030 Identities = 26/181 (14%), Positives = 59/181 (32%), Gaps = 22/181 (12%) Query: 451 HRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQA--AVLTHDVVEREPQDPGVV-R 507 A + A +++ + +E + + L ++ ++E E + + Sbjct: 49 EVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINL 108 Query: 508 LK---RAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYS---PPLKDNWRGFAGF 561 LK ++ + N+ I+G E + DL P+ + F Sbjct: 109 LKDYFSSLTIDNMISKMISGVVT--EELKNYTSSLDDLVNGANLFIIDPMPNVL--FT-- 162 Query: 562 GYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWR 621 D S G G+ + + + R E +AE +F + + W + + Sbjct: 163 --RDPFASIGNGVT---INKMFTKVRQ--RETIFAEYIFKYHPVYKENVPIWLNRWEEAS 215 Query: 622 I 622 + Sbjct: 216 L 216
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.1 bits (96), Expect = 6e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 36.9 bits (85), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 350 bits (898), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 4 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 63 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 64 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 123 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 124 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 183 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 184 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 235 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 425 bits (1095), Expect = e-151 Identities = 157/363 (43%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 5 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 64 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 65 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 124 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 125 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 184 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 185 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 240 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 241 QNMQVNVTPQDAKVVINLRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 300 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 301 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 360 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 361 AKL 363 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 507 bits (1306), Expect = 0.0 Identities = 310/313 (99%), Positives = 311/313 (99%) Query: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSERTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSE TRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGNSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQALSQLVQKAVPRNYDDSLPG+SKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAVSAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTA SAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 682 bits (1761), Expect = 0.0 Identities = 545/546 (99%), Positives = 545/546 (99%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYVDRTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAYVD TAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 46.2 bits (109), Expect = 8e-08 Identities = 42/226 (18%), Positives = 80/226 (35%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTETAPFSEADGDYVGGTESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + DG E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 63.9 bits (155), Expect = 3e-12 Identities = 41/226 (18%), Positives = 79/226 (34%), Gaps = 12/226 (5%) Query: 590 PAEQSAPKAEAKPERQQDRR-----KPRQNNRRDRNERRDTRSERTEGSDNREENRRNRR 644 P+ S + A+ + N ++++++ D E +NR Sbjct: 1008 PSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNRE 1067 Query: 645 QAQQQTAETRESRQQAEV------TEKARTTDEQQAPRRERSRRRNDDKRQAQQEAKALN 698 A++ + + + Q EV T++ +TT+ ++ E+ + + + Q+ K + Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK-VT 1126 Query: 699 VEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEA 758 + QE + + + R +N K Q+ P E + E V E+ Sbjct: 1127 SQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Query: 759 PAPRTELVKVPLPVVAQAAPEQQEENNADNRDNGGMPRRSRRSPRH 804 T V P A Q N+ + RRS RS H Sbjct: 1187 TTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Score = 62.0 bits (150), Expect = 1e-11 Identities = 46/287 (16%), Positives = 91/287 (31%), Gaps = 35/287 (12%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAAPVVAPAPKAATATPASPAQPGLL 571 P E+ + DVP P+ E A AP P A ATP+ + Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE---- 1038 Query: 572 SRFFGALKALFSGGEETKPAEQSAPKAEAKPERQQDRRKP-RQNNRRDRNERRDTRSER- 629 AE S +++ + +QD + QN + + + ++ Sbjct: 1039 -----------------TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQ 1081 Query: 630 -TEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRRRNDDKR 688 E + + E + + ++TA + + TEK + + + + + + Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 689 QAQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAP 743 QA+ + +N++E Q + +P + + Q V +V V P Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 744 VVEETVAAEPIVQEAPAPRTELVKVPLPVVAQAAPEQQEENNADNRD 790 +P V + K ++ P E + D Sbjct: 1200 ENTTPATTQPTVNSESS---NKPKNRHRRSVRSVPHNVEPATTSSND 1243
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 28.6 bits (64), Expect = 0.007 Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 7/66 (10%) Query: 57 IMLAQHALLIAISSDLNAYGVVCEFDWN----DGNGQEGWPPMDGSEGIRITD---IDTS 109 + LA L I + D +G +F DG GQ G+ IT+ +D Sbjct: 22 VRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALILDHW 81 Query: 110 GIFDSD 115 GI +D Sbjct: 82 GIVKAD 87
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 27.5 bits (61), Expect = 0.043 Identities = 17/77 (22%), Positives = 27/77 (35%), Gaps = 11/77 (14%) Query: 2 KNIAAQMVNFDREQM-----------RRIANNMPEQYDEKPQVQQVAQIINGVFSQLLAT 50 N+A ++ DR +++A+ E Y V V +IIN + Sbjct: 165 TNVARRIALMDRTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224 Query: 51 FPASLANRDQNELNEIR 67 SL D EI+ Sbjct: 225 IIESLEEEDPELAEEIK 241
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 508 bits (1310), Expect = 0.0 Identities = 241/388 (62%), Positives = 280/388 (72%), Gaps = 33/388 (8%) Query: 21 MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKHYFSSNDADDGDTTYAR 80 MK+ +A+ V ++L A +A AAEIYNKD NKLDLYGKV+ HYFS + + DGD TY R Sbjct: 1 MKRKVLAL--VIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMR 58 Query: 81 LGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAFAGLKFGDYGSIDYGRNYG 140 +GFKGETQINDQLTG+GQWEY + N E +G++ TRLAFAGLKFGDYGS DYGRNYG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQANTTEGEGANS-WTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 141 VAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNNDFFGLVDGLNFAAQYQGKND 200 V YD+ WTD+LPEFGGD++T D +MTGR GVATYRN DFFGLVDGLNFA QYQGKN+ Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 201 R----------------TDVTEANGDGFGFSTTYEY-EGFGVGATYAKSDRTDGQVAYGK 243 D+ NGDGFG STTY+ GF GA Y SDRT+ QV G Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 244 SKFNASGKNAEVWAAGLKYDANNIYLATTYSETQNMTVFG------NNHIANKAQNFEAV 297 + A G A+ W AGLKYDANNIYLAT YSET+NMT +G + +ANK QNFE Sbjct: 238 T--IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVT 295 Query: 298 AQYQFDFGLRPSVAYLQSKGKDLGVH----GDRDLVKYVDVGATYYFNKNMSTFVDYKIN 353 AQYQFDFGLRP+V++L SKGKDL + D+DLVKY DVGATYYFNKN ST+VDYKIN Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 354 LID-DSKFTKTAGIDTDDIVAVGLVYQF 380 L+D D F K AGI TDDIVA+G+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>PF06291#Lambda prophage Bor protein Length = 102 Score = 186 bits (473), Expect = 3e-65 Identities = 102/102 (100%), Positives = 102/102 (100%) Query: 1 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA 60 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA Sbjct: 1 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA 60 Query: 61 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ Sbjct: 61 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 68.9 bits (168), Expect = 2e-17 Identities = 33/82 (40%), Positives = 46/82 (56%) Query: 41 ADEPRQLVTVYPRYPEYAAANYIKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKA 100 A PR L P+YP A A I+G V+VKFD+ DG V + L ++P N+F EV A Sbjct: 150 ASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNA 209 Query: 101 MAKWRFEKNRPCQGVKRQFIFT 122 M +WR+E +P G+ +F Sbjct: 210 MRRWRYEPGKPGSGIVVNILFK 231
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 31.2 bits (70), Expect = 0.011 Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 316 TRDGLMFFSARGDEIPPPRSITFHIWTAYSPFTTWVQIVYD 356 R+ L+ F R DE P ++T W++ + ++ + + D Sbjct: 36 HREHLLEF-IRLDEPAPLNAMTLAQWSSPNVLSSLLAVYSD 75
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.2 bits (96), Expect = 2e-05 Identities = 56/377 (14%), Positives = 125/377 (33%), Gaps = 36/377 (9%) Query: 236 SGLTAMARQFHNVTAEQIAYVAQLQRSGDESGALQAANEAATKGFDDQTRRLKENMGTLE 295 S R+ +E+ + + +L+ + + + + L+ L Sbjct: 95 SNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALA 154 Query: 296 TWADRTARAFKSMWDAVLDI-GRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARA 354 +A + + + T + EA + + + + Sbjct: 155 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 214 Query: 355 RYWDDREKARLALEAARK-KAEQQSQQDKNAQQQSDTEASRLKYTEEAQKAYERLQTPLE 413 ++ K + ++ + EA + + + L+ + Sbjct: 215 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 414 KYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHA 473 TA ++ + L+A+ L + A + + R D++ Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQ-SQVLNANRQSLR----------RDLDASRE 323 Query: 474 ALLTLQAELRTLEKHAGANEKISQQ-RRDL-------WKAESQFAVLEEAAQRRQLSAQE 525 A L+AE + LE+ +E Q RRDL + E++ LEE + + S Q Sbjct: 324 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383 Query: 526 KS--LLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIDAKSRGL 583 L A ++ + ++ L K+ E+LN +++ K ++++A Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKA------------ 431 Query: 584 TDRQAEREATEQRLKEQ 600 + QA+ EA + LKE+ Sbjct: 432 -ELQAKLEAEAKALKEK 447
>PF06291#Lambda prophage Bor protein Length = 102 Score = 27.7 bits (61), Expect = 0.014 Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 5/40 (12%) Query: 135 MTGILFSLGASMVLGGVAQML-----APKARTPRTQTTDN 169 M +LFS +M++ G AQ P A TP+ T + Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHH 45
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 2e-05 Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 15/132 (11%) Query: 123 SQSAAAAKKSETAAASSRNA--AKTSETNAGNSAKAAASSKTAAQNAATAAERSETNARA 180 S + A+ E A ++T+ET A NS + + + + Q+A + N Sbjct: 1012 SNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ---NREV 1068 Query: 181 SEEASADSEEASRRN--AESAAENAGVATTKAREAAADATKAGQKKDEALSAATRAEKAA 238 ++EA ++ + ++ N A+S +E +E TK ++ A EK Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSE--------TKETQTTETKETATVEKEEKAKVETEKTQ 1120 Query: 239 DRAEVAAEVTAE 250 + +V ++V+ + Sbjct: 1121 EVPKVTSQVSPK 1132
>adhesinb#Adhesin B signature. Length = 310 Score = 329 bits (846), Expect = e-115 Identities = 90/296 (30%), Positives = 163/296 (55%), Gaps = 7/296 (2%) Query: 9 MLLGGLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDAAEVSSITKPGAEIHEYQP 68 +G A + + + + K V+ T +IIAD+ KN+AGD + SI G + HEY+P Sbjct: 13 AFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHEYEP 72 Query: 69 TPGDIKRAQGAQLILANGMNLEL----WFQRFYQHLNGVPE---VIVSSGVTPVGITEGP 121 P D+K+ A LI NG+NLE WF + ++ VS GV + + Sbjct: 73 LPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQS 132 Query: 122 YEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQRNADTYKAKITQTLAPLRKQI 181 +GK +PHAW++ +N +IY NI L + DPAN +TY++N Y K++ +++ Sbjct: 133 EKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKF 192 Query: 182 TELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNHIPAV 241 +P ++ +VTSEG F Y ++ + Y+W IN +++GTP Q++ +V+ ++K +P++ Sbjct: 193 NNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSL 252 Query: 242 FSESTISDKPARQVARETGAHYGGVLYVDSLSTENGPVPTYIDLLKVTTSTLVQGI 297 F ES++ D+P + V+++T ++ DS++ + +Y ++K + +G+ Sbjct: 253 FVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYNLEKIAEGL 308
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 42.0 bits (98), Expect = 9e-08 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Query: 8 TRSIYRELGATLSYNMRLGNGMEIEPWLKAAVRKEFVDDNRVKVNSDGNFINDLSGRRGI 67 S+ LG + + L G +++P++KA+V +EF V N + +L G R Sbjct: 811 GSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAH-RTELRGTRAE 869 Query: 68 YQAGIKASFSSTLSGHLGVGYSRGAGVESPWNAVVGVNWSF 108 G+ A+ S + YS+G + PW G +S+ Sbjct: 870 LGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>SECA#SecA protein signature. Length = 901 Score = 57.2 bits (138), Expect = 2e-12 Identities = 16/28 (57%), Positives = 20/28 (71%) Query: 125 IDGTRPQFGRNDPCPCGSGKKFKKCCGQ 152 + GRNDPCPCGSGKK+K+C G+ Sbjct: 872 AQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 4e-21 Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 3/152 (1%) Query: 10 ILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKL 69 IL+ +D+ R++L+ S G + ++ + DL++ D+ MP N L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 LEHIRNSGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMF 129 L I+ + PVLV+SA KA G D L KP DL L ++ L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRAL--AEP 122 Query: 130 NSRVEEEERLFRDWDAMVDNPAAAAKLLQELQ 161 R + E +D +V AA ++ + L Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 253 bits (648), Expect = 1e-87 Identities = 234/239 (97%), Positives = 236/239 (98%), Gaps = 1/239 (0%) Query: 6 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQA 65 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMV PADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 66 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQ-PKRDVKPVESR 124 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV++ PKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 185 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 243 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 30.2 bits (68), Expect = 0.013 Identities = 13/56 (23%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 204 ESDYLKLQA--LFARVAEEKHR-RGELEKLHHQLVDTYTSLN-RQYAELLSEYKHL 255 +SD LK ++ L V +R + + L++ L + Y ELL+ + Sbjct: 293 KSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYA 348
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.7 bits (87), Expect = 2e-04 Identities = 38/231 (16%), Positives = 71/231 (30%), Gaps = 12/231 (5%) Query: 377 TLQSDMEKAGELAARDRAERESSQLKYTGEAQKAYERLQTPLDKYTARQKELNKALKDGK 436 + ++ + E D + + ++ + L+ AR+ +L KAL+ Sbjct: 109 SEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAM 168 Query: 437 ILQADYNTLMASAKKDYESTLKKPSGVKVSAGERQEDRAHAALLALETELRTLEKHSGVN 496 SAK K + + E+ + A A +++TLE Sbjct: 169 NFSTAD-----SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 223 Query: 497 E---KISQQRRDLWEAESQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKI 553 ++ + S K + + + E EK KI Sbjct: 224 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 554 E-HQKRLNELAQQAARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLRE 603 + + L + A E Q A + R L A RE+++Q E Sbjct: 284 KTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL---DASREAKKQLEAE 331
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.032 Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 128 ILFSMGAAMTLGGVAQML-----APKARTPRTQTTDN 159 +LFS AM + G AQ P A TP+ T + Sbjct: 9 MLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHH 45
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 30.3 bits (68), Expect = 0.001 Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 2/49 (4%) Query: 35 KNIDELSGCISRQWAGNGTPITSLPIEN-GVSL-LVPQAMGGYDVVLDI 81 +N+ ++G ++ + A P ++ +N G+S+ + P AM G ++VLDI Sbjct: 289 QNVPFITGRVTGESANVNNPFQTVERQNVGISMSVFPVAMAGGNIVLDI 337
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 138 bits (350), Expect = 4e-44 Identities = 63/200 (31%), Positives = 98/200 (49%), Gaps = 30/200 (15%) Query: 1 MRKVCAVILSAAICLSVSGAPAWASEHQSTLSAGYLHARTNAPGSDNLNGINVKYRYEFT 60 M+K+ + AA+ +G A ST++ GY + + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DA-LGLITSFSYANAEDEQKTHYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYSMAGV 119 ++ LG+I SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVTIDLAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+V +D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDAFIVGIGYRF 199 S +I G+GYRF Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 45.8 bits (108), Expect = 8e-07 Identities = 54/319 (16%), Positives = 116/319 (36%) Query: 152 ARAASTSAGQAASSAQSASSSAGTASTKAREAAKSAAAAESSKSAAATSASAAKTSETNA 211 + S S AA A + S+A T+A +AA++ AAAE+ A A + + + Sbjct: 39 GKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIV 98 Query: 212 AASQQSAATSASTATTKASEAATSARDASASKEAAKSSETNAASSASSAASSATAAANSA 271 + + A+ +AT A + + AK+ E + ++ + A Sbjct: 99 NEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRK 158 Query: 272 KAAKTSETNARSSETAAGQSASAAADSKTAAALSASAASTSAGQASASATAAGKSAESAA 331 + + R + A + AA S+ A A+ + SA Q+ ++ Sbjct: 159 EIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSR 218 Query: 332 SSASTATTKAGEAAVQASAAARSASAAKTSKTNAKASETSAESSKTAAASSASSAASSAS 391 S+S A + + ++AK + + + S ++ A Sbjct: 219 LSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRV 278 Query: 392 SASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAED 451 A ++E +Q +A++ + T+ + + + +++ + AE K+A++ Sbjct: 279 GAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQN 338 Query: 452 IASAVALEDASTTKKGIVQ 470 ++DA Q Sbjct: 339 NLLNSQIKDAVDATVSFYQ 357 Score = 36.6 bits (84), Expect = 5e-04 Identities = 66/358 (18%), Positives = 125/358 (34%), Gaps = 30/358 (8%) Query: 313 AGQASASATAAGKSAESAASSASTATTKAGEAAVQASAAARSASAAKTSKTNAKASETSA 372 +G KS SAA A+ + A QA AAR+ +AA ++ A Sbjct: 32 SGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAA--------EAQAKA 83 Query: 373 ESSKTAAASSASSAASSASSASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSK 432 ++++ A + A +AS+ + + + A+ A +A A+++ Sbjct: 84 KANRDALTQRLKDIVNEALRHNASRTPSATELA-------HANNAAMQAEDERLRLAKAE 136 Query: 433 STAESAATRAETAAKRAEDIASAVALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAA 492 A A AE A + AE + E A T ++ ++L+ A +L+ KAV+ A Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIEREKAETERQ--LKLAEAEEKRLAALSEEAKAVEIA 194 Query: 493 YELANGKYTAQDATTAQKGIVQLSNATNSTSEMLAATPKSVKAAYDLANGKYTAQDATTA 552 + + AQ +V++ + + L+++ + A GK +A Sbjct: 195 ---------QKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASA 245 Query: 553 QKGIVQLSSATNSTSEMLAATPKSVKAAYDLANGKYTAQDAT-TAQKGIVQLSSATNSAS 611 + + A P + ++ + A QK + + N + Sbjct: 246 K---YKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRIN 302 Query: 612 ETLAATPKAVKAANNNANGRVPSARKVNGKALSADITLTPKDIGTLNSTTMSFSGGAG 669 + KA+ +NN N + + A L I T+SF Sbjct: 303 ADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLT 360 Score = 31.2 bits (70), Expect = 0.022 Identities = 52/321 (16%), Positives = 99/321 (30%), Gaps = 23/321 (7%) Query: 114 SRNASAVAQNTAAAKKSASDASASASEAATHATDAAASARAASTSAGQAASSAQSASSSA 173 S++ S+ A + A +A A +AA A A A+A + + + Sbjct: 43 SKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEAL 102 Query: 174 GTASTKAREAAKSAAAAESSKSAAATSASAAKTSETNAAASQQSAATSASTATTKASEAA 233 +++ A + A A ++ A AK + A + A KA + A Sbjct: 103 RHNASRTPSATELAHANNAAMQAEDERLRLAK---------AEEKARKEAEAAEKAFQEA 153 Query: 234 TSARDASASKEAAKSSETNAAS------SASSAASSATAAANSAKAAKTSETNARSSE-T 286 R ++A + A +A S + A A +A SE E Sbjct: 154 EQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIK 213 Query: 287 AAGQSASAAADSKTAAALSASAASTSAGQASASATAAGKSAESAASSASTA-TTKAGEAA 345 S++ ++ A + + QASA + + + A+ + A Sbjct: 214 TLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEA 273 Query: 346 VQASAAARSASAAKTSKTNAKASETSAESSKTAAASSASSAASSASSAS------ASKDE 399 + A K + A + + ++ A S S+ +A A ++ Sbjct: 274 TRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENL 333 Query: 400 ATRQASAAKGSATTASTKATE 420 Q + A Sbjct: 334 KKAQNNLLNSQIKDAVDATVS 354
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 29.9 bits (67), Expect = 0.005 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 41 TKEHLLPHFL-EHVGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 93 T EHL F+ H+ + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 94 AGESKI 99 ++KI Sbjct: 114 ENQNKI 119
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 115 bits (289), Expect = 7e-31 Identities = 61/414 (14%), Positives = 128/414 (30%), Gaps = 105/414 (25%) Query: 12 VVAIGILLAGVVFFIW-WVSK--------GRFIQTTDDAYIGGNITTVASKVSGYISAIE 62 +VA I+ V+ FI + + G+ G + + + I Sbjct: 59 LVAYFIMGFLVIAFILSVLGQVEIVATANGKLT-------HSGRSKEIKPIENSIVKEII 111 Query: 63 VRDNQSVKKGDIILRLDDRDYRANVARLEAKIKSSKANLESIQATI-------------- 108 V++ +SV+KGD++L+L A+ + ++ + ++ Q Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 109 -------------AMQQSIIQSASETWQAVKHEEQKRLRD--------TERYEKLAQSAA 147 S+I+ TWQ K++++ L R + + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 148 ISQQIIDNAR-------FDYQQVAAKERKAANDFLVEKQRLAVLSAQEENVRASIEEVQA 200 + + +D+ V +E K L V +Q E + + I + Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA----VNELRVYKSQLEQIESEILSAKE 287 Query: 201 ALTQ-----------------------------ALLDLEYTLVRAPIDGIVANRSAHT-G 230 + +++RAP+ V HT G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 231 SWVEGGTSLVSLVPVSE-LWVDANYKENQIAGMKPGMKAEIRADILKGEVFH---GHIES 286 V +L+ +VP + L V A + I + G A I+ + + G +++ Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 287 LSPATGASFSLIPIENATGNFTKIVQRVPVRIAFDDAKELKQLLRPGLSVTVSV 340 ++ + G ++ + K + L G++VT + Sbjct: 408 INLDA-------IEDQRLGLVFNVIISIEENCLSTGNKNIP--LSSGMAVTAEI 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 101 bits (254), Expect = 3e-25 Identities = 80/418 (19%), Positives = 170/418 (40%), Gaps = 21/418 (5%) Query: 3 SMRKHIAFASMCIGLFIAQLDIQIVSSSLNEIGGGLSAGKDEMAWLQTSYLIAEIIVIPL 62 ++R + +CI F + L+ +++ SL +I + W+ T++++ I + Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 63 SGWLSRVFSTRWLFTLSAGIFTLMSIACGLAWN-IQIMIFFRALQGVAGASMIPLVFTTA 121 G LS + L I S+ + + ++I R +QG A+ LV Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVV 128 Query: 122 FIYYQGKELGLAAAVVSALASLSPTLEPTLGGWITDNLDWRWLFYINILPGIYLVLSIPF 181 Y + G A ++ ++ ++ + P +GG I + W +L I ++ ++++PF Sbjct: 129 ARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI----TIITVPF 184 Query: 182 LVNFDKPDLSLLKVADYPSIILLAMTLGCLEYTLEEGARWGWLDDNTILLTSVLALVSFI 241 L+ K ++ + D IIL+++ + +L +++++SF+ Sbjct: 185 LMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS-YSISFL---------IVSVLSFL 234 Query: 242 LFAARTLKISNPIMDLHAFKDKYFTLGCFFSFSGGVGIFSTVYLIPVFLGQVRGLNAEEI 301 +F K+++P +D K+ F +G + V ++P + V L+ EI Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 302 GFAVCTTG-IFQLFSVPFYFWLSKKINLQWLLMAGLGGFVFSMYL--FTPITHEWGWQEL 358 G + G + + L + ++L G+ S F T W + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTI 353 Query: 359 LFPQAIRGISQQFAMAPIVTLTLGGIPKERLKLASGVFNLTRNLGGASGIALCGSILN 416 + + G+S F I T+ + ++ + N T L +GIA+ G +L+ Sbjct: 354 IIVFVLGGLS--FTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 0.004 Identities = 23/163 (14%), Positives = 59/163 (36%), Gaps = 18/163 (11%) Query: 109 SGVAQAQREAEKAGKLAAAQQEAQAQVFQRMLDKIDPLAAALRNLEQQQDELNAAFASGK 168 S + QA+ E + L+ + + + ++ D+ + + + + F++ + Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKLPEL-KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 169 INGSQFENYSRKIQETRRELTGEAQAEREAAKAHDEQVAALQRLIAQLDPVGTAFNRLVE 228 Q E K + R + ++ ++ L+ + A + ++E Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA---IAKHAVLE 256 Query: 229 QQKQLNEAKAKGMLSPEMYEELSGKLRAMRSELEVTQSQLSKT 271 Q+ + EA +LR +S+LE +S++ Sbjct: 257 QENKYVEA--------------VNELRVYKSQLEQIESEILSA 285
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 149 bits (378), Expect = 3e-48 Identities = 68/200 (34%), Positives = 101/200 (50%), Gaps = 30/200 (15%) Query: 1 MRKLCAVILSAVVWLVAAGTPASAAEHQSTLSAGYLQSHTDMPGNDDLKGVNVKYRYEFT 60 M+K+ + A V AGT +A ST++ GY QS N + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSMMAGPSVRVNEWFSAYAMAGV 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.8 bits (108), Expect = 6e-07 Identities = 28/192 (14%), Positives = 62/192 (32%), Gaps = 7/192 (3%) Query: 103 PEALRRFEEMVEEAARNAEAASQSAAAAKKSETAAASSKNAAKTSETNAANSAQAAAASQ 162 + + E+ E + E ++ + K E + A E + + + + Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 163 TASANSATAAKKSETNAKNSETAAKTSETNAKSSQTAAKTSETNAKA---SETAAKNSQN 219 +A++ AK++ +N + T + T T + T+ + SE++ K Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 220 AAAESESAAAGSATSAAGSATAAANSQKAAKTSETNAKSSQTAAKTS----ETNAKASET 275 S + S + + ++ TNA S AK S+ Sbjct: 1223 HRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQH 1282 Query: 276 AAKNSQDAAAQS 287 ++ + Q Sbjct: 1283 ISQLEMNNEGQY 1294 Score = 42.4 bits (99), Expect = 9e-06 Identities = 28/152 (18%), Positives = 50/152 (32%), Gaps = 13/152 (8%) Query: 222 AESESAAAGSATSAAGSATAAANSQKAAKTSETNAKSSQTAAKTSETNAKASETAAKNSQ 281 + + S + A +A A S+T +E + + S+T KN Q Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 282 DA------------AAQSESAAAGSASAAASSATASANSQKAAKTSETNAKASETAAANS 329 DA A+S A + A S + + +Q + E A + Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 330 AKASAASQTAAKASEDAAREYASQ-AAEPYKQ 360 K + ++ S + Q AEP ++ Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 308 bits (791), Expect = e-109 Identities = 86/250 (34%), Positives = 132/250 (52%), Gaps = 21/250 (8%) Query: 5 LIAFLCTLIITGCSDG--------------IGDSPSPPGKNVELVGIPGQGVAVASNGTS 50 + L +++ GCS G + P+ P + + +PG G A+ +NG Sbjct: 10 IAGILIPILLNGCSSGKNKAYLDPKVFPPQVEGGPTVPSPDEPGLPLPGPGPALPTNGAI 69 Query: 51 PTFGSNSTDFPDVSIMSTGGAMLTVWARPVRNWLWGYTPFDSVSFGENRNWKVVDGKDAG 110 P + VS+M+ G++LT+W+R + LW Y DS SFGE RNW+++ G Sbjct: 70 PIPEPGTAPA--VSLMNMDGSVLTMWSRGAGSSLWAYYIGDSNSFGELRNWQIMPGTRPN 127 Query: 111 TVKFVNVAQGTCMEAFK-----NGVIHNTCDDNSLSQEFQLLPSTNGNVLIRSSALQTCI 165 T++F NV GTCM +F + C +FQ + + NGN ++S + CI Sbjct: 128 TIQFRNVDVGTCMTSFPGFKGGVQLSTAPCKFGPERFDFQPMATRNGNYQLKSLSTGLCI 187 Query: 166 RADYLSRTILSPFAFTITLEKCPGAKEETQEMLWAISPPVRAAKPNLIKPELRPFRPLPI 225 RA++L RT SP+A T+T+E+CP + E+ E +W+IS P+R A + KPE+RPF P PI Sbjct: 188 RANFLGRTPSSPYATTLTMERCPSSGEKNFEFMWSISEPLRPALATIAKPEIRPFPPQPI 247 Query: 226 PPHDKPDGME 235 P + G E Sbjct: 248 EPDEHSTGGE 257
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 431 bits (1109), Expect = e-157 Identities = 150/264 (56%), Positives = 185/264 (70%) Query: 2 KKLLFLLMILPGISFADLSDFKVATWNLQGSNAPTENKWNTHVRQLVTGSGAVDILMVQE 61 K ++ L++ L + ADL+DF+VATWNLQG++A TE+KWN +VRQL++G AVDIL VQE Sbjct: 3 KYIISLIVFLSFYAQADLTDFRVATWNLQGASATTESKWNINVRQLISGENAVDILAVQE 62 Query: 62 AGSIPSSATLTEREFRTPGIPMNEYIWNTGTNSRPQQLFIYFSRTDALSNRVNLAIVSNR 121 AGS PS+A T +PGIP+ E IWN TNSRPQQ++IYFS DAL RVNLA+VSNR Sbjct: 63 AGSPPSTAVDTGTLIPSPGIPVRELIWNLSTNSRPQQVYIYFSAVDALGGRVNLALVSNR 122 Query: 122 RADEVIVLSPPTVASRPIIGIRIGNDVFFSTHALANRGIDSGAIVNSVFEFFNRQTDPIR 181 RADEV VLSP RP++GIRIGND FF+ HA+A R D+ A+V V+ FF DP+ Sbjct: 123 RADEVFVLSPVRQGGRPLLGIRIGNDAFFTAHAIAMRNNDAPALVEEVYNFFRDSRDPVH 182 Query: 182 QAANWMIAGDFNRSPAMLFSTLEPGIRNHVNIIAPPDPTQASGGVLDYAVVGNSVSFVLP 241 QA NWMI GDFNR PA L L +R II+P TQ S LDYAV GNSV+F Sbjct: 183 QALNWMILGDFNREPADLEMNLTVPVRRASEIISPAAATQTSQRTLDYAVAGNSVAFRPS 242 Query: 242 LLRASLLFGLLRGQIASDHFPVGF 265 L+A +++G R QI+SDHFPVG Sbjct: 243 PLQAGIVYGARRTQISSDHFPVGV 266
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 40.8 bits (95), Expect = 1e-06 Identities = 24/109 (22%), Positives = 39/109 (35%), Gaps = 17/109 (15%) Query: 87 GHVQIKNPDGNECL----AILNGQLAVAKQCTESNRNALFTFITSETGAVQIKSIGNGQC 142 +Q +N D C+ G C F + + G Q+KS+ G C Sbjct: 127 NTIQFRNVDVGTCMTSFPGFKGGVQLSTAPCKFGPERFDFQPMATRNGNYQLKSLSTGLC 186 Query: 143 -----LGNGESV---TDFKLTKCVNDLSRPFDTVSPGLLWMLNPPLSPA 183 LG S T + +C + + F+ +W ++ PL PA Sbjct: 187 IRANFLGRTPSSPYATTLTMERCPSSGEKNFE-----FMWSISEPLRPA 230
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 33.2 bits (75), Expect = 0.005 Identities = 25/133 (18%), Positives = 53/133 (39%), Gaps = 8/133 (6%) Query: 545 GHDQSITVANDRCITVRNDQTLQVTNDRTVSVSNDDGLYVRNDRKVTVEGKQEHKTTGNH 604 G +S + +R + + + Q R+ +S D + + +R + G +T G+ Sbjct: 1091 GP-ESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAGADSTQTAGDR 1149 Query: 605 VSLVEGKHSLVVKGDLARKVSGALGIKVDGDIVLESSSRISLKVGGSFVVIHSGGVDIVG 664 L+ G +S + GD ++ +G D +L + R L G + ++ ++G Sbjct: 1150 SKLLAGNNSYLTAGDRSKLTAG-------NDCILMAGDRSKLTAGINSILTAGCRSKLIG 1202 Query: 665 PKISLNSGGSPGT 677 S + G Sbjct: 1203 SNGSTLTAGENSV 1215 Score = 30.9 bits (69), Expect = 0.027 Identities = 15/69 (21%), Positives = 35/69 (50%) Query: 567 QVTNDRTVSVSNDDGLYVRNDRKVTVEGKQEHKTTGNHVSLVEGKHSLVVKGDLARKVSG 626 Q+ + R+ ++ + + +R + + GK +T G +L+ G S+ + G+ + ++G Sbjct: 1080 QIASHRSSLIAGPESTQITGNRSMLIAGKGSSQTAGYRSTLISGADSVQMAGERGKLIAG 1139 Query: 627 ALGIKVDGD 635 A + GD Sbjct: 1140 ADSTQTAGD 1148
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 27.9 bits (62), Expect = 0.033 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 13/51 (25%) Query: 167 LNDMYAFIPGDNYYFIKS------SGYKFVND-------KWFTLKSINNIF 204 + M AFI D Y FIKS +G+ ND K ++ I ++F Sbjct: 4 VIKMEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVF 54
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 31.2 bits (70), Expect = 0.001 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPIETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 940 bits (2430), Expect = 0.0 Identities = 498/869 (57%), Positives = 653/869 (75%), Gaps = 10/869 (1%) Query: 15 QVLILPRFARLTFALGLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYR 74 + + F RL A A AE YFNPRFL++D DLS F G+E PPGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 75 VDIYLNDEFMASRDITFIADDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSADKHVPDN 134 VDIYLN+ +MA+RD+TF D+ ++PCL+ L S+G+ +++ + ++ + Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV-------SGMNLLAD 132 Query: 135 SACTPLQDRLADASSEFDVGQQHLSLSVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFD 194 AC PL + DA+++ DVGQQ L+L++PQ ++ ARGY+ P+LW+ GINAGLLNY+F Sbjct: 133 DACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFS 192 Query: 195 GNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTS 254 GNS N G S+YAYLNLQSG+NIG+WRLRDN+TWSYNS S+S NKWQHINT Sbjct: 193 GNS---VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 255 AERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTA 314 ERDIIPLRSRLT+GD YT GDIFD +NFRG ++ S + MLPDSQ GFAPVIHGIARGTA Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 315 QVSVKQNGYDVYQTTVPPGPFTIDDINSAANGGNLQVTIKEADGSIQTLYVPYSSVPVLQ 374 QV++KQNGYD+Y +TVPPGPFTI+DI +A N G+LQVTIKEADGS Q VPYSSVP+LQ Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 375 RAGYTRYALAMGEYRSGNNLQSTPKFVQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGK 434 R G+TRY++ GEYRSGN Q P+F Q++L+HGL WT YGG Q+A+ Y+AFN GIGK Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGK 429 Query: 435 DLGLFGAFSFDITQANTTLADDTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNL 494 ++G GA S D+TQAN+TL DD++H GQSV+ +Y+KS ++GTNIQ+ GYRYST G++N Sbjct: 430 NMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 495 SDSAYSRMSGYTVKPPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASR 554 +D+ YSRM+GY ++ G + F DY+NL Y+KRG+ Q++++QQLG T + S S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 555 QSYWNTSRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTD 614 Q+YW TS D+Q GLN F DI +L+YS + N WQ RD +LA +N+PFSHW+R+D Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSD 609 Query: 615 SQSAFHNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTQGGNTSSGTSGYS 674 S+S + +++ASYSMS+DL G MTNL+GVYGTLL DNNL+YSVQ G GG+ +SG++GY+ Sbjct: 610 SKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYA 669 Query: 675 SLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNV 734 +LNYRG YGN N+GYS S D Q+YYG+SGG++AHA+G+T GQPL DT+VLVKAPGA + Sbjct: 670 TLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDA 729 Query: 735 KIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARAT 794 K+ENQTG+ TDWRGYA+LP+ATEYRENRVAL+ N+LADNV+LD V V+PT GAI RA Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 795 FNAQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGK 854 F A++G K+LMTL + NK +PFGA+VT +++ IVA+NGQVYL+G+P +GK+QV WG+ Sbjct: 790 FKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGE 849 Query: 855 DKNSNCIVDYKLPVVSPGTLLNQQTAICR 883 ++N++C+ +Y+LP S LL Q +A CR Sbjct: 850 EENAHCVANYQLPPESQQQLLTQLSAECR 878
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 34.8 bits (80), Expect = 3e-04 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 1 MRILVAGATGSIGIHVVNTAIAMGHQPVTL---------VRNRRKIKLLPRGTDIFY-GD 50 M+ LV GA G IG HV + GHQ V + + +++LL + F+ D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 51 VSIPETLTDLPKD 63 ++ E +TDL Sbjct: 61 LADREGMTDLFAS 73
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.5 bits (131), Expect = 3e-10 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 8/192 (4%) Query: 36 LSDIAHSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLS 95 L DIA+ F+ A + T + ++ + + ++ Q+ ++LL+ ++ V+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FLSWS-FTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGL 154 F+ S F++L+++R A F ++ + R P R +A LI + A+ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 PLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSI 214 +G ++ Y W I + +IT+ L+KLL + LMS+ Sbjct: 157 AIGGMIAHYIHWSY-LLLIPMITIITVPFLMKLLK------KEVRIKGHFDIKGIILMSV 209 Query: 215 YLLTVVVVTAHY 226 ++ ++ T Y Sbjct: 210 GIVFFMLFTTSY 221
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.7 bits (103), Expect = 9e-07 Identities = 42/239 (17%), Positives = 83/239 (34%), Gaps = 18/239 (7%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVIFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSNSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEK---------IIATETGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYV 233 S K + W + A L F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRW--ARGMTVVAALMAV--FFIMQLVGQVPAALWVIFG 237 Score = 34.0 bits (78), Expect = 0.001 Identities = 22/155 (14%), Positives = 60/155 (38%), Gaps = 2/155 (1%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVIF-SLGFGI 65 +AL+A ++ + I+ ++ IG ++ + + ++ G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 66 LADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFADNL 125 +A + ++R ++L + A +G+I + + L+ + L+A + + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQV 328 Query: 126 SSNSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI 160 + ++ + ++ +GP L T + SI Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (251), Expect = 1e-27 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAIEEMLASLPAEWSNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 228 INTL 231 ++ L Sbjct: 248 MHNL 251
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 28.7 bits (64), Expect = 0.031 Identities = 16/100 (16%), Positives = 34/100 (34%), Gaps = 19/100 (19%) Query: 183 DISVNWQGAAKAYSFDEVIVDSNGKKLDMRFGGNLTAAEEKKTGCLVCLDSCPVGIVSNA 242 ++ V+W+ + + +V++ + G + ++ G G LV Sbjct: 298 ELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGA--------LGSLV--------DARGL 341 Query: 243 TYTYGAV---EKRGEVKFKGNASVLPADNTPATVTFKITE 279 Y V E G + ++L +N A + T Sbjct: 342 DYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETY 381
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 36.9 bits (85), Expect = 3e-05 Identities = 35/192 (18%), Positives = 55/192 (28%), Gaps = 58/192 (30%) Query: 8 PPRALLLV-DLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVI-----ASQD--- 58 P RA+LL+ D+QN F +L + C G V+ SQ+ Sbjct: 28 PNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 59 -------WHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAI 111 W P + + + P D + T W Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDDDLV-LTKW---------------------- 124 Query: 112 AAVFHKGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDAL 171 YSAF +T L + +R ++LI+ G+ T +A Sbjct: 125 -------------RYSAFK------RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAF 165 Query: 172 QLGYKVNVITDG 183 K + D Sbjct: 166 MEDIKAFFVGDA 177
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 1/129 (0%) Query: 88 ALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMY-WLIFFRFLMGTG 146 A M + IG+ G + D G +R ++I + + LI RF+ G G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 147 MGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWRIMFLLGG 206 A + +IP RGK + + + AIG ++ + W + L+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 207 IGILLAWFL 215 I I+ FL Sbjct: 177 ITIITVPFL 185
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 29.3 bits (65), Expect = 0.021 Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 13/81 (16%) Query: 165 ETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 213 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 214 TDRVYLNPQDCSVINDEALNR 234 ++ +P D ++ E L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 510 bits (1314), Expect = 0.0 Identities = 240/388 (61%), Positives = 282/388 (72%), Gaps = 33/388 (8%) Query: 1 MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKHYFSSNDADDGDTTYVR 60 MK+ +A+ V ++L A +A AAEIYNKD NKLDLYGKV+ HYFS + + DGD TY+R Sbjct: 1 MKRKVLAL--VIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMR 58 Query: 61 LGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAFAGLKFGDYGSIDYGRNYG 120 +GFKGETQINDQLTG+GQWEY + N E +G++ TRLAFAGLKFGDYGS DYGRNYG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQANTTEGEGANS-WTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 121 VAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNNDFFGLVDGLNFAAQYQGKND 180 V YD+ WTD+LPEFGGD++T D +MTGR GVATYRN DFFGLVDGLNFA QYQGKN+ Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 181 R----------------TDVTEANGDGFGFSTTYEY-EGFGVGATYAKSDRTNDQVIYGN 223 D+ NGDGFG STTY+ GF GA Y SDRTN+QV G Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 224 NSLNASGQNAEVWAAGLKYDANNIYLATTYSETQNMTVFG------NNHIANKAQNFEVV 277 A G A+ W AGLKYDANNIYLAT YSET+NMT +G + +ANK QNFEV Sbjct: 238 T--IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVT 295 Query: 278 AQYQFDFGLRPSVAYLQSKGKDLG----AWGDQDLVEYIDVGATYYFNKNMSTFVDYKIN 333 AQYQFDFGLRP+V++L SKGKDL D+DLV+Y DVGATYYFNKN ST+VDYKIN Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 334 LIDKSD-FTKASGVATDDIVAVGLVYQF 360 L+D D F K +G++TDDIVA+G+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (293), Expect = 8e-38 Identities = 102/103 (99%), Positives = 102/103 (99%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTVARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQT ARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 459 bits (1183), Expect = e-162 Identities = 287/324 (88%), Positives = 304/324 (93%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSGRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQSNTSGRDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPIS 326 +GYPGGVPGALSNQPAP N API+ Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIA 328
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 341 bits (876), Expect = e-119 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 369 bits (948), Expect = e-133 Identities = 224/228 (98%), Positives = 226/228 (99%) Query: 1 MSDNLPWKTWMPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTW PDDLAPPQAEFVP+VEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHEQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGH+QGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPRVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAP VV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 202 bits (514), Expect = 4e-70 Identities = 145/147 (98%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQKRQST 120 +TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQ+RQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 468 bits (1206), Expect = e-168 Identities = 366/375 (97%), Positives = 370/375 (98%) Query: 1 MIRLAPLITANVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITA+VDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLVSDIVSDAQQADLLIPVDETLPVINDEQSTSTPLTTAQTMTLAAVADKNTTKDEKA 120 GEPL+SDIVSDAQQA+LLIPVDET PVINDEQSTSTPLTTAQTM LAAVADKNTTKDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLP EKPTLFTKLTS QLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTADASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTA ASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMISPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQM+SPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQGRVTGNSGVDIFA 375 LQGRVTGNSGVDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 385 bits (989), Expect = e-136 Identities = 85/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 20 ILSQAEIDALLNGDS--EVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFA 77 +LSQ EID LL S + E +S I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 78 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 137 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 138 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 197 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 198 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 255 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 256 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 312 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 313 GVPVLTSQYGTLNGQYALRIEHLI 336 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 210 bits (537), Expect = 5e-74 Identities = 126/137 (91%), Positives = 134/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSGKSAADAVFQQFGGGDVSGALQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T+ KSAADAVFQQ GGGDVSGA+QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 335 bits (860), Expect = e-119 Identities = 242/245 (98%), Positives = 244/245 (99%) Query: 1 MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRLLSVAPVLLWL+TPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFNEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPF+EEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGEQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKG QPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.044 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 32.9 bits (75), Expect = 8e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 37 AQKLAADDDVDMLVILTACYFHDIVSLAKDHPQRQRSSILAAEETRRLLREEFVQFPA-- 94 +KLA + + D+ +ILT + +L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEEG--HFKAGS 273 Query: 95 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 124 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 444 bits (1144), Expect = e-158 Identities = 205/395 (51%), Positives = 256/395 (64%), Gaps = 36/395 (9%) Query: 11 MKRKVLAMLVPALLVAGAANAAEIYNKDGNKVDFYGKMVGERIWSNTDDNNSENEDTSYA 70 MKRKVLA+++PALL AGAA+AAEIYNKDGNK+D YGK+ G +S D++S++ D +Y Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFS---DDSSKDGDQTYM 57 Query: 71 RFGVKGETQITSELTGFGQFEYNLDASKPEGE-NQEKTRLTFAGLKYNELGSFDYGRNYG 129 R G KGETQI +LTG+GQ+EYN+ A+ EGE TRL FAGLK+ + GSFDYGRNYG Sbjct: 58 RVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 130 VAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNYDFFGLVDGLDFAIQYQGKNS 189 V YD +TDML E+GGDS+ ADN+M GR NGVATYRN DFFGLVDGL+FA+QYQGKN Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 190 NRS----------------TKKQNGDGYALSVDYNI-NGFGIVGAYSKSDRTNDQVA--- 229 ++S + NGDG+ +S Y+I GF AY+ SDRTN+QV Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 230 -DGNGSNAELWSLAAKYDANNVYAVVMYGETRNMTPGSIDTGVADREGNTIMRDQLINET 288 G A+ W+ KYDANN+Y MY ETRNMTP + + + N+T Sbjct: 238 TIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYG--------KTDKGYDGGVANKT 289 Query: 289 QNFEAVVQYQFDFGLRPSLGYVYSKGKDIKGVPGHRYVDADRVNYIEVGTWYYFNKNMNV 348 QNFE QYQFDFGLRP++ ++ SKGKD+ D D V Y +VG YYFNKN + Sbjct: 290 QNFEVTAQYQFDFGLRPAVSFLMSKGKDL-TYNNVNGDDKDLVKYADVGATYYFNKNFST 348 Query: 349 YTAYKFNMLDKDDA--AITGAAADDQFAVGIVYQF 381 Y YK N+LD DD G + DD A+G+VYQF Sbjct: 349 YVDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF 383
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 28.3 bits (63), Expect = 0.038 Identities = 7/29 (24%), Positives = 14/29 (48%) Query: 160 GLPESEDVAAALQWAIENDRFVISLCHGP 188 G + + + + +AIE +IS+ G Sbjct: 122 GSGQYDWIIQGIYYAIEQKVDIISMSLGG 150
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 1e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 39 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 98 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 99 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 154 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>cloacin#Cloacin signature. Length = 551 Score = 32.4 bits (73), Expect = 0.003 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 6/88 (6%) Query: 36 EWNRAKAELDALDEQIAREEELRRQDQAYVDESGPEERQNNEAENGKKAVEEKRAAAFNR 95 + RA+AEL+ +E +AR +E QA + + +A N A FNR Sbjct: 322 NYERARAELNQANEDVARNQE----RQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNR 377 Query: 96 FLRAGFAELNAEERNLMRELRAQSVTTD 123 F A + + M L+AQ TD Sbjct: 378 FAHDPMAGGHRMWQ--MAGLKAQRAQTD 403
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 51.2 bits (122), Expect = 2e-08 Identities = 22/70 (31%), Positives = 44/70 (62%) Query: 28 QQLRERLIQELNLTPQQLHEESNLIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLA 87 + +R+++ + L TP+ + ++ +L+ GLDS+R+M + +R+ G +T EL PT+ Sbjct: 233 ENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIE 292 Query: 88 AWNQLMLSRS 97 W +L+ +RS Sbjct: 293 EWQKLLTTRS 302
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 45.8 bits (108), Expect = 1e-06 Identities = 32/156 (20%), Positives = 55/156 (35%), Gaps = 19/156 (12%) Query: 1561 LVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCR------CDVGD 1614 +TGA G+G L +GA + A + L V R DV D Sbjct: 12 FITGAAQGIGEAVARTLASQGAH---IAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 1615 AGQLATVLDDLAAN-GGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQLLQTLR 1673 + + + + G I ++ AGVL + L D + A F+V + +++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 1674 NH-----DGRYLILYSSAAAT----LGAPGQSAHAL 1700 + G + + S+ A + A S A Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAA 164
>INTIMIN#Intimin signature. Length = 939 Score = 75.1 bits (184), Expect = 2e-17 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 181 QQIASTSQLIGSLLAEDMNSEQAANIARGWASSQASGVMTDWLSRFGTARITLGVDEDFS 240 QQ AS + S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224
>INTIMIN#Intimin signature. Length = 939 Score = 65.5 bits (159), Expect = 4e-13 Identities = 63/344 (18%), Positives = 123/344 (35%), Gaps = 24/344 (6%) Query: 301 SGGKVRTNSSGQA--------PVVLTSNKVGTYTVTASFHNG-VTIQTQTTVKVTGNPS- 350 GG+++ + S A V + V T A NG + T+ V N Sbjct: 495 QGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQV 554 Query: 351 --TAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLTVYFALKSGSTTLTSLTAV 408 V F AD ++ A ++ T ATV+ +G + V F + SG+ L++ +A Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 409 TDQNGIATTSVKGAITGSVTVSTVTSAGGMQTVDISLVAVPADASQSILKNNQSSLKGDF 468 T+ +G AT ++K V + +A ++ + V SI + Sbjct: 614 TNGSGKATVTLKSD-KPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVA 672 Query: 469 TDSAELHLVLHDISGNPIKVSEGMEFVQSGTNVPYMKISAIDYSQNINGDYKATVTGDGE 528 + + + G+ ++ + F + + S + NG K T+T Sbjct: 673 NGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKL-----SNSTEKTDTNGYAKVTLTSTTP 727 Query: 529 GIATLIPVLNGVHQAGLSTTIEFISAETRPMTGTVSVNGANLPTASFPSQGFTGAYYQLN 588 G + + ++ V + +EF G + + G + P+ L Sbjct: 728 GKSLVSARVSDVAVDVKAPEVEFF-TTLTIDDGNIEIVGTGV-KGKLPTVWLQYGQVNL- 784 Query: 589 NDNFAPGKTAADYSFSSSASWVGVDATGKVTFKNDGDSNTVIIT 632 + G + ++ A ++G+VT K G + +I+ Sbjct: 785 --KASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVIS 826 Score = 52.0 bits (124), Expect = 7e-09 Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 16/233 (6%) Query: 13 AVTDADGKAKVTLKGTKAGAHTVTASMVGGKS--EQLVVNFTADTLTAQVNLNVTEDNFI 70 A T+ GKA VTLK K G V+A S V F T + + + + Sbjct: 612 ANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAV 671 Query: 71 ANNIGMTRLQATVTDGNGNPVEGIKVNFRGTSVTLSSTSVETDDQVFAEILVTSTEVGLK 130 AN V PV +V F T LS+++ +TD +A++ +TST G Sbjct: 672 ANGQDAITYTVKVMK-GDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 131 TVSASLADKPTEVISRLLN----AKVDVNSATI----TSQEIPEGQVMVAQDIAVKAHVN 182 VSA ++D +V + + +D + I ++P + Q + N Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN 790 Query: 183 DQFGNPVTHQPATFSAAPSSQMIISQNTVSTNTQGVAEVTMTPERNGSYTVKA 235 ++ + A S Q+ + + +T + V + + +YT+ Sbjct: 791 GKYTWRSANPAIASVDASSGQVTLKEKGTTTIS-----VISSDNQTATYTIAT 838 Score = 51.6 bits (123), Expect = 7e-09 Identities = 45/170 (26%), Positives = 64/170 (37%), Gaps = 7/170 (4%) Query: 271 TLTATLTSANGTPVEGQVINFSVTLEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTAS 330 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V+A Sbjct: 579 TYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK 637 Query: 331 FHNGV-TIQTQTTVKVTGNPSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGL 389 + + V + A + AD +T A D T V G + Sbjct: 638 TAEMTSALNANAVIFVDQ--TKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQ 694 Query: 390 TVYFALKSGSTTLTSLTAVTDQNGIATTSVKGAITGSVTVSTVTSAGGMQ 439 V F G + + T TD NG A ++ G VS S + Sbjct: 695 EVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVD 742 Score = 40.4 bits (94), Expect = 2e-05 Identities = 35/213 (16%), Positives = 63/213 (29%), Gaps = 18/213 (8%) Query: 4 NFTLSDGDKAVTDADGKAKVTLKGTKAGAHTVTASMVGGKSE--QLVVNFTADTLTAQVN 61 TD +G AKVTL T G V+A + + V F N Sbjct: 701 TLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGN 760 Query: 62 LNVTEDNFIANNIGMTRLQATVTDGNGN-PVEGIKVNFRGTSVTLSSTSVETDDQVFAEI 120 + + + + + G N G + S + SV+ Sbjct: 761 IEI-----VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQ---- 811 Query: 121 LVTSTEVGLKTVSASLADKPTEVISRLLNAKVDVNSATITSQEIPEGQVMVAQDIAVKAH 180 VT E G T+S +D T + + + ++ + V ++ Sbjct: 812 -VTLKEKGTTTISVISSDNQT--ATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGG--- 865 Query: 181 VNDQFGNPVTHQPATFSAAPSSQMIISQNTVST 213 N + + + AA + S T+ + Sbjct: 866 KLPSSQNELENVFKAWGAANKYEYYKSSQTIIS 898
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 39/259 (15%), Positives = 96/259 (37%), Gaps = 18/259 (6%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHNQAAAKKRIPVIEALLRHPGAFLKIIA 257 W L ++ ++ ++ +++ + + + ++ +L + + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 258 LRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRR 317 + + L +++ + + GL + + IG+L GG+ T+ F + + Sbjct: 228 VSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 318 VYITGALIGTLSAFPFFMA 336 ++ A IG++ FP M+ Sbjct: 287 HQLSTAEIGSVIIFPGTMS 305
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.2 bits (107), Expect = 1e-07 Identities = 33/170 (19%), Positives = 63/170 (37%), Gaps = 25/170 (14%) Query: 1 MNILLFGKTGQVGWELQRALAPLGN-LIALDVHSTDY--------------------CGD 39 M L+ G G +G+ + + L G+ ++ +D + Y D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 40 FSNPEGVAETVKRIRPDVIVNAAAHTAVDKAESEPEFAQLLNATSVESIAKAANEVG-AW 98 ++ EG+ + + + + AV + P N T +I + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 99 VIHYSTDYVFPGNGDTPWLEMDATA-PLNVYGETKLAGEKALQEHCAKHL 147 +++ S+ V+ N P+ D+ P+++Y TK A E L H HL Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE--LMAHTYSHL 168
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 181 bits (462), Expect = 1e-56 Identities = 88/360 (24%), Positives = 149/360 (41%), Gaps = 48/360 (13%) Query: 1 MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLT--YAGNL-ESLADVSDSERYVFEHA 57 MK LVTG AGFIG V + ++ VV +D L Y +L ++ ++ + F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDAAAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSA 117 D+ D M +FA + V V S+ P A+ ++N+ G +LE R+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LDGDKKNSFRFHHISTDEVYGDLPHPDEVNNKEQLPLFTETTAYAPSSPYSASKASSDHL 177 + S+ VYG ++P T+ + P S Y+A+K +++ + Sbjct: 117 ------KIQHLLYASSSSVYGL---------NRKMPFSTDDSVDHPVSLYAATKKANELM 161 Query: 178 VRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVE 237 + YGLP YGP+ P+ + LEGK++ +Y G RD+ Y++ Sbjct: 162 AHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYID 221 Query: 238 D-------------HARALYTVVTEGQA-----GETYNIGGHNEKKNIDVVLTICDLLDE 279 D HA +TV T A YNIG + + +D + + D L Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG- 280 Query: 280 IVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRELGWKPQETFESGIRKTVEWYLANAK 339 + +K+ +PG + D + + +G+ P+ T + G++ V WY K Sbjct: 281 -IEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.8 bits (124), Expect = 3e-09 Identities = 48/369 (13%), Positives = 106/369 (28%), Gaps = 87/369 (23%) Query: 53 SYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPG-----ATKQAQQSPAGGR------- 100 S + R V ++ IA G+ + + A G + + Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 101 --RGMRAG-PLA---PVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDG--QLMALHF 152 +R G L + A + L T ++ ++ +L Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 153 QEGQQVKAGDLLAEI------------DPSQFKVALAQAQGQLA-------KDKATLANA 193 Q V ++L Q ++ L + + + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 194 RRDLSRYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVA----------------- 236 + L + L +++ + Q+ E ++ ++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 237 --------------------------SAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSG 269 + + S I APV +V LK G +++ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 270 DTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSL 328 +T +V++ + +++ + DI + Q A + VEA+ T L + ++L Sbjct: 354 ETL-MVIVPEDDTLEVTALVQNKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINL 410 Query: 329 DNQIDATTG 337 D D G Sbjct: 411 DAIEDQRLG 419
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 920 bits (2379), Expect = 0.0 Identities = 300/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 913 bits (2361), Expect = 0.0 Identities = 288/1035 (27%), Positives = 503/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+A+L ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 ++ +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRGERS---ETAQQIIDRLRKKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP ER+ +A+ +I R + +L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALQLFNAPFSLIALIGIMLLIGIVKKNAIMMVYFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 79.5 bits (196), Expect = 4e-17 Identities = 76/448 (16%), Positives = 160/448 (35%), Gaps = 26/448 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRGERSETAQQIIDRLRKKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L+ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQANASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQEDNGAE-- 703 V ++ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLIYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALQLFNAPFSLIALIGIMLLIGIVKKNAIMMVYFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPKQA 1022 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGG 510
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 125 bits (316), Expect = 1e-33 Identities = 97/429 (22%), Positives = 189/429 (44%), Gaps = 23/429 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLM-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + LM L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKL 257 G +L++VG+ L F+ + V V++ ++++ H + L Sbjct: 202 KGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRNFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYTWLSMAF 441 +Y+ L + F Sbjct: 428 LYSNLLLLF 436
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 34.0 bits (78), Expect = 0.001 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALSTLLAALATF------PLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSE 217 RQ + L+ A L AL P L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GRLAEDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>SECA#SecA protein signature. Length = 901 Score = 27.9 bits (62), Expect = 0.024 Identities = 10/60 (16%), Positives = 23/60 (38%) Query: 23 GKHLAVPRWQETCDYYNQMMERERLTVCFHAQLKQRHATMRFEEMNDVERERLVCAIDEL 82 L + W + ++ RER+ +++ + E M E+ ++ +D L Sbjct: 715 DLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSL 774
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 26.6 bits (58), Expect = 0.027 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 11/88 (12%) Query: 18 EGEMKKIAAISLISVFLMSGCAVHNDETSIGKFGLAYKSNIQ-------RKLDNQYYTEA 70 + ++KKI +S+++ ++ GC+ H ++ I K AYK + L+ E Sbjct: 2 KNQVKKILGMSVVAAMVIVGCS-HAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK 60 Query: 71 EASLARGRISGAENIVKNDAVHFCVTQG 98 + + GR AE+++ N+ V + Q Sbjct: 61 YSGVFLGR---AEDLITNNDVDYSTNQA 85
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 31.6 bits (71), Expect = 0.004 Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSLE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQMQGVLRELRFNQLILETAGVPQTVELA 246 A + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 17/268 (6%) Query: 29 LSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGAVLMYFAAQQ 88 L S G A A+ ++G+++DRF ++ + ++ AGA + Y Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAI--- 89 Query: 89 TTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIG-WIASGLACGF 147 A F +L + T A T ++A A + D+ R R G + G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 148 LPQMLGY-ADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILL 206 P + G SP + P A + L + FL K + + L A Sbjct: 148 -PVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRW 205 Query: 207 RDKN------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFML 260 VFF + +P A + IF G + + Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265 Query: 261 ALPFFTKRFGIKKVLLLGLVTAAIRYGF 288 R G ++ L+LG++ Y Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYIL 293 Score = 34.0 bits (78), Expect = 0.001 Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L++G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVN 372 + V D R G ++ C GFG + G LGG+M F+ P Sbjct: 109 TGATGAVAGAYIAD-ITDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGG--FSPHAP-- 162 Query: 373 GLTFNWAGMWTFGAVMIAIIAVLFMIFFRESDN 405 + A + + + ES Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186 Score = 28.6 bits (64), Expect = 0.049 Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 4/114 (3%) Query: 7 LSFMMFVEWFIWGAWFVPLWLWL----SKSGFSAGEIGWSYACTAIAAILSPILVGSITD 62 ++ +M V + + VP LW+ + + A IG S A I L+ ++ Sbjct: 212 VAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 63 RFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYSLTYMPTIALTNSIA 116 ++ L + M A A T FP+++ + + AL ++ Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLS 325
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.024 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 66 KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 106 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.5 bits (63), Expect = 0.043 Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 93 NITLSNNQ---TSFTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSA-----SSS 144 NI LS N+ T T + T++ S ++ + S G + + + + S+S Sbjct: 297 NIILSKNEDQSTQNTDSQTRTISKNTSTSRTHTSEVHGNAEVHASFFDIGGSVSAGFSNS 356 Query: 145 TRGSAAVQFLLCLLGGKSW 163 + A+ L L G ++W Sbjct: 357 NSSTVAIDHSLSLAGERTW 375
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 2e-14 Identities = 22/113 (19%), Positives = 48/113 (42%), Gaps = 2/113 (1%) Query: 19 VMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 78 +++ DD +R + Q L +G++V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 79 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 131 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.5 bits (69), Expect = 0.015 Identities = 19/124 (15%), Positives = 46/124 (37%), Gaps = 20/124 (16%) Query: 339 EMHNGKLTIVG-----RLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEF--- 390 E +G + G +++ + + ++++ + H +++ + + + ++ Sbjct: 19 ESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVNSDYGVI 78 Query: 391 ---------GHRPVAVVEYDQQSVDLDEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQ 441 GHR V EY SV + + V + + L P + GIK Q Sbjct: 79 KDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDC-IELAPLHNPANI--EGIKACTQ 135 Query: 442 ALKE 445 + + Sbjct: 136 IMPD 139
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 32.1 bits (73), Expect = 5e-04 Identities = 13/74 (17%), Positives = 29/74 (39%), Gaps = 12/74 (16%) Query: 1 MIDWQDLHHSDLSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLEGENRHIL 52 M++ D++H+ LS ++ L LR F + D ++ ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNN----TTYLF 56 Query: 53 GWHNGTLVAYARIL 66 G + T++ R + Sbjct: 57 GIKDNTVICSLRFI 70
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 251/251 (100%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADSLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD+LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 25.6 bits (56), Expect = 0.033 Identities = 6/31 (19%), Positives = 19/31 (61%) Query: 56 EGYTFIPNAFLEKLLKEDISVSQFNDVLKVF 86 + + IP+ +++ + + + F+D+L++F Sbjct: 111 KEWVDIPDFLIKRWQEGKMLDAWFSDILRLF 141
>PF07675#Cleaved Adhesin Length = 1358 Score = 27.8 bits (61), Expect = 0.037 Identities = 14/52 (26%), Positives = 24/52 (46%) Query: 133 MTAPAGLSIPEGMIILVDPEVEPRNGKLVVAKLEGENEATFKKLVIDAGRKF 184 +T + IP G+ EP +GK+ +A G A + +AG+K+ Sbjct: 458 VTGQGEVVIPGGVYDYCITNPEPASGKMWIAGDGGNQPARYDDFAFEAGKKY 509
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 122 bits (308), Expect = 2e-32 Identities = 92/404 (22%), Positives = 167/404 (41%), Gaps = 17/404 (4%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIILLTVVSVISLISLVIWES 257 ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLIS-PLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376 G M ++I + G ++ ++ +V + S T F II+ G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 377 FAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 + ++TI S L + S+ NF LS G ++ Sbjct: 362 LSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 74.1 bits (182), Expect = 1e-16 Identities = 47/277 (16%), Positives = 94/277 (33%), Gaps = 46/277 (16%) Query: 61 AKNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDYNRRV----PLAKQGVIS 113 K + Q + L + AE + + Y+ R+ L + I+ Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 114 KEALEHTKDTLI----------SSKAALNAAIQAYKANKALVMNTPLNRQPQVIEAADAT 163 K A+ ++ + S + + I + K + T L + + + T Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE--YQLVTQLFKNEILDKLRQTT 308 Query: 164 KE----------AWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPGQSLMAVVPARQ-MWV 211 + + I++PV+ + Q V G V+ ++LM +VP + V Sbjct: 309 DNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEV 368 Query: 212 NANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNAFSLLPAQNATGNWIK 271 A + + + +GQ+ I + F G +G + + Sbjct: 369 TALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK---VKNINLDAIEDQRLG 419 Query: 272 IVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 304 +V V +S++ L PL G+++TA I T Sbjct: 420 LVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-17 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 2e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.024 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%) Query: 34 QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATA 93 Q + ++ + + + E+ Q Q K AT +KA+ + + Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122 Query: 94 DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153 K Q + +S +Q Q + + V I + D Q + + Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177 Query: 154 NMTE 157 N+ + Sbjct: 1178 NVEQ 1181
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.019 Identities = 12/90 (13%), Positives = 32/90 (35%), Gaps = 14/90 (15%) Query: 374 VDDGVTARAIENRLLEEQAAQLLPRGDRQVYQSEIANSQRIIENLTEQRAQILAEDPAGS 433 + A+ + +LE++ + + +VY+S++ + I + E+ + Sbjct: 244 LHKQAIAK---HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL----- 295 Query: 434 GKALSRARSDKQARLRDIDQRIRQAQERLE 463 +++ +LR I L Sbjct: 296 ------FKNEILDKLRQTTDNIGLLTLELA 319
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.6 bits (63), Expect = 0.023 Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 6/81 (7%) Query: 16 NEQPVDGGTAPAASEPSAPAGDNPAPVGDPSQQEGDKPQPVADGDKPADDKKPENDKQDE 75 N QP+ P S PA +NPAP +P + +P P + D D + D Sbjct: 324 NAQPL-----PEVSPAENPA-NNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDS 377 Query: 76 KKDGDKPEGAPEKYEFQAAEG 96 D+P G K + +G Sbjct: 378 PAVPDRPNGRHRKERKEGEDG 398
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 116 bits (292), Expect = 1e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 41 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 93 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 94 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 153 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 154 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 212 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 213 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 272 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 273 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 322 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 323 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 379 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 380 PDKVVAIGAAI 390 P VA G Sbjct: 321 PLTCVARGGGK 331
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 106 bits (267), Expect = 1e-30 Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 21/151 (13%) Query: 18 GCQSPQGKFTPEQVAAMQSYGFTESAGDWSLGLSDAILFAKNDYKLLPESQQQIQTMAAK 77 G +P P +Q+ FT L +LF N L PE Q + + ++ Sbjct: 194 GEAAPVVAPAPAPAPEVQTKHFT---------LKSDVLFNFNKATLKPEGQAALDQLYSQ 244 Query: 78 LASTGLTHARMD--GHTDNYGEDSYNEVLSLKRANVVADAWAMGGQIPRSNLTTQGLGKK 135 L++ + G+TD G D+YN+ LS +RA V D + + IP ++ +G+G+ Sbjct: 245 LSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVD-YLISKGIPADKISARGMGES 303 Query: 136 YPIASNKTAQGR---------AENRRVAVVI 157 P+ N + A +RRV + + Sbjct: 304 NPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>cloacin#Cloacin signature. Length = 551 Score = 27.8 bits (61), Expect = 0.029 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Query: 50 PYGFTARANSGAEAVVLFPDGDRSHAVVVTVSD 82 P GFT N+ +AV+ FP +AV V+VSD Sbjct: 258 PAGFTQGGNT-RDAVIRFPKDSGHNAVYVSVSD 289
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 27.9 bits (62), Expect = 0.024 Identities = 10/45 (22%), Positives = 18/45 (40%), Gaps = 5/45 (11%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDL 40 M QR I E + + +EL ++ T T+ +D+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDI 45
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 372 bits (956), Expect = e-126 Identities = 125/388 (32%), Positives = 193/388 (49%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RLGLSRVVLSAGARNLLQHYNFPGNVRELEHAIHRAVVLSRATRSGDEVIL-----EAQH 433 + GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPPPEAAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + + V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.035 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%) Query: 5 TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 59 T++ E+AK AGV++ + + + +E P L Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 60 KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 92 L VT + E++FH E Sbjct: 92 ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.4 bits (84), Expect = 2e-04 Identities = 53/338 (15%), Positives = 123/338 (36%), Gaps = 34/338 (10%) Query: 93 LGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 151 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 152 GHTLLAEFSPRRHRGVLLGAFSVVWT----VGYVLASIAGHHFISESPEAWRWLLASAAL 207 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 208 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLF-- 265 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 266 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 312 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 313 LNALLIVGALLGLVLTHLLAHRRFLLGSFLLLTATLVVMACLPSGSSLTLLLFVLFSTTI 372 + ++ G + ++ ++ G +L + ++ S F+L +T+ Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS-----VSFLTASFLLETTSW 349 Query: 373 SAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVS 410 +V +L SF + S V + GA +S Sbjct: 350 FMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMS 387
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (274), Expect = 8e-31 Identities = 74/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%) Query: 36 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEK-QGVEVD 94 M+ ++GK A +TG G+G+A A LA GA++ + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 95 FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 154 D+ A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 155 FELSYEAAKIMIPQKSGKIINICSLFSYSGGQWSPAYSATKHALAGFTKAYCDELGQYNI 214 F S +K M+ ++SG I+ + S + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 215 QVNGISPGYYATDI--TLATRSNPETNQRVLDY-------IPANRWGDTQDLMGAAVFLA 265 + N +SPG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 266 SPASNYVNGHLLVVDGG 282 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.006 Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 41 GFSNTEIGLIMSTFGIAAIIFYA-PSGVIADKFSHRKMITSAMIITGLLGLIMATYPPLW 99 + T IG+ ++ FGI + A +G +A + R+ + MI G +++A W Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 100 VMLCIQVAFAITTILM 115 + I V A I M Sbjct: 302 MAFPIMVLLASGGIGM 317 Score = 30.6 bits (69), Expect = 0.012 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIIFYAPSGVIADKFSHRKMITSAMIITGLLGLIMATYPPLWVMLCIQVA 107 G++++ + + G ++D+F R ++ ++ + IMAT P LWV+ ++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 30.3 bits (68), Expect = 0.005 Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 30 NASWSEVLNQYQRRTDLIPNLVASIKGYSSHEQEVLEAVTLARSQANRASSDLQKTPGDE 89 +AS ++ ++ Q D + L S GY + + N+ + P + Sbjct: 294 SASIEQIQSKIQELGDTLEELRDSFDGY------------INNAFVNQIHLNFVMPPQAQ 341 Query: 90 QKLQAWQQAQAQAQAQ 105 Q+ QQ QAQA AQ Sbjct: 342 QQQGQGQQQQAQATAQ 357
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 80.4 bits (198), Expect = 1e-18 Identities = 44/142 (30%), Positives = 63/142 (44%), Gaps = 14/142 (9%) Query: 402 PEQKMEVTASLQVQTVRLDSMSLFDVGQARLKDGSTKVL---VDALVNIRAKPGWLILVA 458 +Q + L S LF+ +A LK L L N+ K G ++V Sbjct: 200 VAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDG-SVVVL 258 Query: 459 GYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATCFAVQGLGESQPAATNDTPQGR-- 516 GYTD G + NQ LS RRA++V ++ L + IPA + +G+GES P N + Sbjct: 259 GYTDRIGSDAYNQGLSERRAQSVVDY-LISKGIPADKISARGMGESNPVTGNTCDNVKQR 317 Query: 517 -------AVNRRVEISLVPRSD 531 A +RRVEI + D Sbjct: 318 AALIDCLAPDRRVEIEVKGIKD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.011 Identities = 35/189 (18%), Positives = 66/189 (34%), Gaps = 34/189 (17%) Query: 512 IMTLRQEGTDSTELQQQLRTHQGFAPLLALDVDARAVATVVADWTG----IPLSSLL--- 564 + + ++ +L +++ + P+L + + + A G +P L Sbjct: 52 VTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Query: 565 RDEQSDLLSMEQSLENR----------VVGQRPALCAIAQRL-RAAKTGLTPENGPQGVF 613 L+ + ++ +VG+ A+ I + L R +T LT Sbjct: 112 IGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT--------L 163 Query: 614 LLTGPSGTGKTETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGGV 673 ++TG SGTGK A L D + IN++ S+L G + G Sbjct: 164 MITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGA 215 Query: 674 LTEAVRKRP 682 T A + Sbjct: 216 FTGAQTRST 224
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 30.6 bits (69), Expect = 0.042 Identities = 15/71 (21%), Positives = 24/71 (33%), Gaps = 6/71 (8%) Query: 274 LRLAHTLAERGIAHWQSVL---KPLLAGGAFSSLRLRGLMFSPPLAAVPEAAPHAWLPSP 330 + +T ER I +S L G F + RG + +P +P Sbjct: 243 WQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLP---DSQRGFAP 299 Query: 331 VWAGVTGDNAR 341 V G+ A+ Sbjct: 300 VIHGIARGTAQ 310
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.010 Identities = 13/83 (15%), Positives = 35/83 (42%), Gaps = 9/83 (10%) Query: 33 ESKSVASAVFYKQIKILHLDFFSR---------SALNTDAEDTPLSTMVHVWQLKTREDF 83 + + V+Y+ K + LD S+ + + + ++D+ S ++ + K + + Sbjct: 161 INSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLEL 220 Query: 84 DKADYDTLFMQEEKTLEKDVLAK 106 + D F++E T + + Sbjct: 221 NNKSIDINFIKENLTEFQHAFSL 243
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.048 Identities = 34/215 (15%), Positives = 62/215 (28%), Gaps = 20/215 (9%) Query: 235 WPIFMAGMVVMAGLGGTGLW-GWSQLNQPDALIQRIQLSVMPLP-QSLESGELAKLDVKD 292 P + +M L + Q+ ++ S + +E+ + ++ VK+ Sbjct: 56 RPRLV-AYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 293 -------KALLAQDRT-----IAASQMQLEQLNKLPARWPLEQGYRQLRQLDAL----WP 336 LL +Q L Q R+ + +L +L L P Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 337 DNPQVRALNAQWRKQRELSALSAEALNGYAQAQSQLQRLSAQLDALDERKGRYLTGSELK 396 V S N Q + L + A+ + R RY S ++ Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQ-NQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 397 TAVYGIRQSLKEPPLEELLRQLEEQKQTGEVSPTL 431 + SL LE++ + E L Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNEL 268
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 41.1 bits (96), Expect = 2e-06 Identities = 45/212 (21%), Positives = 67/212 (31%), Gaps = 47/212 (22%) Query: 4 MKKVIVVSALAMAGVFSAQALADRGKTGFYVTGKAGASVVTQTDQRFRQDFGDDVYKYKG 63 MKK + A+A+AG + A + T +Y K G S + D + Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNT-WYTGAKLGWS-----------QYHDTGFINNN 48 Query: 64 GDKNDTVFGAGLAVGYDFYQHYNVPVRTEVEFYGRGAADSHYTLDTWHSPMGDGGREDTQ 123 G ++ GAG GY V ++ GR + G Q Sbjct: 49 GPTHENQLGAGAFGGYQVNP--YVGFEMGYDWLGRMPYKGS----------VENGAYKAQ 96 Query: 124 NRLSVNTLMVNTYYDFRNSSAFTPWVSVGLGYARIHHKATYTDTSWNKSGEVSDISALHY 183 V Y + +T +G R DT N G+ Sbjct: 97 ---GVQLTAKLGYPITDDLDIYT---RLGGMVWR-------ADTKSNVYGKN-------- 135 Query: 184 SGYDNNFAWSIGAGVRYDITPDIALDLSYRYL 215 +D + GV Y ITP+IA L Y++ Sbjct: 136 --HDTGVSPVFAGGVEYAITPEIATRLEYQWT 165
>PF03627#PapG Length = 336 Score = 602 bits (1554), Expect = 0.0 Identities = 336/336 (100%), Positives = 336/336 (100%) Query: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT Sbjct: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 Query: 61 WNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF 120 WNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF Sbjct: 61 WNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF 120 Query: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVTIPYTSGMQ 180 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVTIPYTSGMQ Sbjct: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVTIPYTSGMQ 180 Query: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY Sbjct: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 Query: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY Sbjct: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 Query: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP Sbjct: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 268 bits (685), Expect = 2e-95 Identities = 155/167 (92%), Positives = 157/167 (94%), Gaps = 1/167 (0%) Query: 11 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE 70 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE Sbjct: 1 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE 60 Query: 71 ITKTISISCTYKSGSPWIKVTGNAMA-GQTNVLATNIANFGIALYQGKGMSTPLTLGNGS 129 +TK ISISC YKSGS WIKVTGN M GQ NVLATNI +FGIALYQGKGMSTPLTLGNGS Sbjct: 61 VTKNISISCPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNGS 120 Query: 130 GNGYRVTAGLDTARSTFTFTSVPFRNGSRTLNGGDFRTTASMSMIYN 176 GNGYRVTAGLDTARSTFTFTSVPFRNGS LNGGDFRTTASMSMIYN Sbjct: 121 GNGYRVTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMIYN 167
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 296 bits (760), Expect = e-106 Identities = 124/173 (71%), Positives = 142/173 (82%) Query: 1 MKKIRGLCLPVMLGAVLMSQHVHAVDNLTFRGKLIIPACTVSNTTVDWQDVEIQTLSQNG 60 MKKIRGLCLPVMLGAVLMSQHVHA DNLTF+GKLIIPACTV N V+W D+EIQ L Q+G Sbjct: 1 MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVQNAEVNWGDIEIQNLVQSG 60 Query: 61 NHEKEFTVNMRCPYNLGTMKVTITATNTYNNAILVQNTSNTSSDGLLVYLYNSNAGNIGT 120 ++K+FTV+M CPY+LGTMKVTIT+ N+ILV NTS S DGLL+YLYNSN IG Sbjct: 61 GNQKDFTVDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGN 120 Query: 121 AITLGTPFTPGKITGNNADKTISLHAKLGYKGNMQNLIAGPFSATATLVASYS 173 A+TLG+ TPGKITG + I+L+AKLGYKGNMQ+L AG FSATATLVASYS Sbjct: 121 AVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASYS 173
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 734 bits (1897), Expect = 0.0 Identities = 241/882 (27%), Positives = 361/882 (40%), Gaps = 67/882 (7%) Query: 1 MRGMKDRI-PFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLP 59 + K R+ F V + +++ + FN L + D +RF + P Sbjct: 16 LHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPP 75 Query: 60 GQYLLDVIVNGQSISPASLQISFVEPALSGDKAEKKLPQACLTSDMVRLMGLTAESLDKV 119 G Y +D+ +N + A+ ++F CLT + MGL S+ + Sbjct: 76 GTYRVDIYLNNGYM--ATRDVTFNTGDSEQGI------VPCLTRAQLASMGLNTASVSGM 127 Query: 120 VYWHDGQCADF-HGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGLML 178 D C + + D G L + +PQA++ ++PP WD GI +L Sbjct: 128 NLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLL 187 Query: 179 DYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNFTW 238 +YN +G +N GG+SH N G N+G WRLR + S S + + + Sbjct: 188 NYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSS--DSSSGSKNKWQH 245 Query: 239 SRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIA 298 +L R I R+ LTLG+ DIF ++ GA L SDD MLP RG+AP I GIA Sbjct: 246 INTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIA 305 Query: 299 ETNARVVVSQQGRVLYDSMVPAGLFSIQDLD-SSVRGRLDVEVIEQNGRKKTFQVDTASV 357 A+V + Q G +Y+S VP G F+I D+ + G L V + E +G + F V +SV Sbjct: 306 RGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSV 365 Query: 358 PYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALAA 417 P L R G RY + +G R + E P F GL W++YGG LA Y A Sbjct: 366 PLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 418 GAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSERN 477 G G ++G G LS D+TQ+ + + + G+S R Y+K + + +I GYR+S Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 478 YMTMEQYLNARYR--------------------NDYSSREKEMYTVTLNKNVADWNTSFN 517 Y +R + + ++ +T+ + + + + Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS-TLY 544 Query: 518 LQYSRQTYWDIRKTD-YYTVSVNRYFNVFGLQGVAVGLAASRSKYLGRD--NDSAYLRIS 574 L S QTYW D + +N F + L+ S +K + + L ++ Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFE-----DINWTLSYSLTKNAWQKGRDQMLALNVN 599 Query: 575 VPLGT------------GTASYSGSMSND-RYVNMAGYTDT-FNDGLDSYSLNAGLNSGG 620 +P +ASYS S + R N+AG T D SYS+ G GG Sbjct: 600 IPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGG 659 Query: 621 GLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGG 680 S A ++R N + S SGG G L G Sbjct: 660 DGNSGSTGYATLNYRGGYGNANIG-YSHSDDIKQLYYGVSGGVLAHANGVTL--GQPLND 716 Query: 681 TRLLVDTDGVGGVPVDGGQVV-TNRWGTGVVTDISSYYRNTTSVDLKRLPDDVEATRSVV 739 T +LV G V+ V T+ G V+ + Y N ++D L D+V+ +V Sbjct: 717 TVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVA 776 Query: 740 ESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLS 799 T GAI +F G +L L + PFGA VTSE + G+VAD G +LS Sbjct: 777 NVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLS 835 Query: 800 GVTPGETLSVNW--DGKIQCQVNVPETAISDQQLL----LPC 835 G+ + V W + C N S QQLL C Sbjct: 836 GMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 30.4 bits (68), Expect = 0.003 Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 27/172 (15%) Query: 29 GMTLPEYWG----EEHVWWDGRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDL-QNGF 83 G+ LP G +HV F G+++ PACT+ + ++ G+ +++L Q+G Sbjct: 6 GLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVQNAE----VNWGDIEIQNLVQSG- 60 Query: 84 SGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGET---PDKFNLSGQAKGINLQI 140 G ++ F++ + NC ++ ++ +T +G G + P+ SG I L Sbjct: 61 -GNQKDFTVDM-NCPYS------LGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYN 112 Query: 141 ADAR--GNIARAGKVMPAIPLTGNEEALDYTLRIVR----NGKKLEAGNYFA 186 ++ GN G + +TG A TL N + L+AG + A Sbjct: 113 SNNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSA 164
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 168 bits (426), Expect = 5e-58 Identities = 104/104 (100%), Positives = 104/104 (100%) Query: 1 MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS 60 MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS Sbjct: 1 MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS 60 Query: 61 RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSAFD 104 RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSAFD Sbjct: 61 RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSAFD 104
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 66/387 (17%), Positives = 130/387 (33%), Gaps = 39/387 (10%) Query: 52 TPYLKEQLDLSATQI---GVLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVN 108 P L L S G+L + + V+ +L+D+ + + L A+ Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY 87 Query: 109 VGLGFSTAFWIFAALVILNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNIGGGI 168 + + W+ I+ G+ G IA+ ER R F +S G G+ Sbjct: 88 AIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERAR--HFGFMSACFGFGM 144 Query: 169 VA-PIVGAAFALLGSEHWQSASYIVPACVAIVFAVIVLILGKGSPHQEGLPSLEEMMPEE 227 VA P++G A + A + + + L +PE Sbjct: 145 VAGPVLGGLMGGFSPH----APFFAAAALNGLNFLTGCFL----------------LPE- 183 Query: 228 KVVLNTRQTVKAPENMSAFQIFCTYVLRNKNAWYVSLVDVFVYMVRFGMISWLPIYLLTV 287 + + + P A ++ +L+ VF M G + + Sbjct: 184 -----SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 288 KHFSKEQMSVAFLFFEWA---AIPSTLLAGWLSDKLFKGRRMPLAMICMALIFICLIGYW 344 F + ++ + ++ ++ G ++ +L + R + L MI +I L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 345 KSESLFMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTS 404 + F + + A G + Q + S Q E GS L ++ I G L T+ Sbjct: 299 RGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS-LTSIVGPLLFTA 357 Query: 405 LFGIMVDHIGWHGGFYLLGCGIICCII 431 ++ + W+G ++ G + + Sbjct: 358 IYAASITT--WNGWAWIAGAALYLLCL 382
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 240 bits (615), Expect = 7e-77 Identities = 113/479 (23%), Positives = 191/479 (39%), Gaps = 83/479 (17%) Query: 10 SILLIDDDADVLDAYTQLLEQSGYRVFACNNPFEAQAWIQPDWPGIVLSDVCMPGCSGID 69 +IL+ DDDA + Q L ++GY V +N WI +V++DV MP + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 70 LMMLFHQDDQQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLSLVEEALRQRQS 129 L+ + LP+L+++ A+ A +KGA+D+L KP D +L+ ++ AL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 130 IIARRQYCQQTLQVELIGRSEWINQYRRRLQQLSETDIAVWLYGAPGTGRMTGARYLHQF 189 ++ + Q L+GRS + + R L +L +TD+ + + G GTG+ AR LH + Sbjct: 125 RPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 190 GRNAQGEFVYRELTPDNAPQLND------------------------FIALAQGGTLVLS 225 G+ G FV N + A+GGTL L Sbjct: 184 GKRRNGPFV-----AINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 226 HPEHLTREQQYHLVQ-LQSQEHRP----------FRLIGIGDTSLVELAASNHIIAELYY 274 + + Q L++ LQ E+ R++ + L + +LYY Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 275 CFAMTQIACLPLTQRPDDIEPLFRHYLCKACQRLNHPVPEVGKEMLKEMMRRMWPNNVRE 334 + + PL R +DI L RH++ +A + V +E L+ M WP NVRE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 335 LANAAE--------------------------------LFTVGVLPLAE---------TA 353 L N G L +++ A Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 354 NPLMHVGTPTPLDRRVEDAERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLS 412 + + DR + + E +I AL +G + A+ L + R L ++++ G+S Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.5 bits (68), Expect = 0.017 Identities = 12/40 (30%), Positives = 18/40 (45%), Gaps = 5/40 (12%) Query: 110 LPVGPVAEK----EQWRHDMLIRFPEDTGTLP-WILLRTP 144 PV E D++I FP D+G P +++ R P Sbjct: 447 TPVKATPETYPGVITLPEDLIIGFPADSGIKPIYVMFRDP 486
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 33.4 bits (76), Expect = 6e-04 Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 137 ITNFLQLVLTWSLLIILS--CGVGLIF----MVVGKTFPEMQKVL---PILLKPLYFISC 187 + L SLL L GL F MVV P + +++ P+ F+S Sbjct: 135 VAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSG 194 Query: 188 IMFPLHSIPKQYWSYLLWNPLVHVVELSREAVMPGYISE-GVSLNYLAMFTLVTLFIGLA 246 +FP+ +P + + + PL H ++L R ++ + + + L ++ ++ F+ A Sbjct: 195 AVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTA 254 Query: 247 LYRTR 251 L R R Sbjct: 255 LLRRR 259
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.011 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 1 MRRARAGFTLLEMLVAIAIFASLA-LMAQQVTNGVTRVNSAVAGHD 45 + R GFTLLE++V I I LA L+ + + + A D Sbjct: 4 TDKQR-GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 32.2 bits (73), Expect = 3e-04 Identities = 13/24 (54%), Positives = 18/24 (75%) Query: 2 KRGFTLLEVMLALAIFALAAMAVL 25 +RGFTLLE+ML L + ++A VL Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVL 26
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 77.3 bits (190), Expect = 3e-20 Identities = 42/196 (21%), Positives = 71/196 (36%), Gaps = 41/196 (20%) Query: 1 MPERGFTLLEIMLVIFLIGLASAGVVQTFATASEPPAKKAAQDFLTRFAQFKDRAVIEGQ 60 M +RGFTLLE+ML++ L+G+++ V+ F + + A + F + + R + GQ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 61 TLGVLIDPPGYQFMQRRHGQWLPVSATRLSAQVTVPKQVQMLLQPGSDIWQKEYALELQR 120 GV + P +QF+ + P D W L L+ Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPA-------------------PADDGWSGYRWLPLRA 101 Query: 121 RRL----TLHDIELEL-----QKEAKKKTPQIRFSPFEPATPFTLRFYSAAQNACWAVKL 171 R+ ++ +L L + P + P TPF L L Sbjct: 102 GRVATSGSIAGGKLNLAFAQGEAWTPGDNPDVLIFPGGEMTPFRLT-------------L 148 Query: 172 AHDGALSLNQCDERMP 187 ++ N E +P Sbjct: 149 GEAPGIAFNARGESLP 164
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 218 bits (556), Expect = 2e-76 Identities = 91/146 (62%), Positives = 109/146 (74%), Gaps = 3/146 (2%) Query: 6 RTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRL 65 R + GFTLLE+MVVIVI+GVLASLVVPNL+GNKEKAD+QKA+SDIVALENALDMY+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 66 DNGRYPTTEQGLEALIQQPANMADARNYRTGGYIKRLPKDPWGNDYQYLSPGEKGLFDVY 125 DN YPTT QGLE+L++ P A NY GYIKRLP DPWGNDY ++PGE G +D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 126 TLGADGQENGEGAGADIGNWNLQEFQ 151 + G DG+ E DI NW L + + Sbjct: 122 SAGPDGEMGTED---DITNWGLSKKK 144
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 453 bits (1167), Expect = e-161 Identities = 226/406 (55%), Positives = 301/406 (74%), Gaps = 1/406 (0%) Query: 1 MALFYYQALERNGRKTKGMIEADSARHARQLLRGKDLIPVHI-EARMNASAGGLLQRRRH 59 MA ++YQAL+ G+K +G EADSAR ARQLLR + L+P+ + E R + G Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 AHRRVATADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHVKSLGMALRSRIQEGYTL 119 R++T+DLAL TRQLATLV A+MPLE L AV++QSEK H+ L A+RS++ EG++L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQRQRLKSRLLQAMLYPLVLL 179 +D+++ P F+ L+C+MVAAGE SGHLD VLNRLADYTEQRQ+++SR+ QAM+YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 VVATGVVTILLTAVVPKIIEQFDHLGHALPASTRMLIAMSDALQASGVYWLAGLLGLLVL 239 VVA VV+ILL+ VVPK++EQF H+ ALP STR+L+ MSDA++ G + L LL + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 GQRLLKNPAMRLRWDKTLLRLPVTGRVARGLNTARFSRTLSILTASSVPLLEGIQTAAAV 299 + +L+ R+ + + LL LP+ GR+ARGLNTAR++RTLSIL AS+VPLL+ ++ + V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 SANRYVEQQLLLAADRVREGSSLRAALADLRLFPPMMLYMIASGEQSGELETMLEQAAVN 359 +N Y +L LA D VREG SL AL LFPPMM +MIASGE+SGEL++MLE+AA N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QEREFDTQVGLALGLFEPALVVMMAGVVLFIVIAILEPMLQLNNMV 405 Q+REF +Q+ LALGLFEP LVV MA VVLFIV+AIL+P+LQLN ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 575 bits (1483), Expect = 0.0 Identities = 295/668 (44%), Positives = 429/668 (64%), Gaps = 34/668 (5%) Query: 24 LLPLMLAAALCSSPVWEEEATFTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRT 83 L L++ AAL P EE F+A+FK TD++ FI TV NLNKT+I+ P V+G +++R+ Sbjct: 11 SLTLLIFAALLFRPAAAEE--FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 84 MTPLNERQYYQLFLNLLEAQGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEM 143 LNE QYYQ FL++L+ G+AV+ M N VLKVV+S AK +P+ + + GDE+ Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPG-IGDEV 127 Query: 144 VTKVVPVRNVSVRELAPILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVD 203 VT+VVP+ NV+ R+LAP+LRQ+ D+AG G+VV+Y+PSNV+++TGRA+V++RL +++RVD Sbjct: 128 VTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVD 187 Query: 204 HAGNRTEEVIPLDNASASEIARVLESLTKNSGENQ-PATLKSQIVADERTNSVIVSGDPA 262 +AG+R+ +PL ASA+++ +++ L K++ ++ P ++ + +VADERTN+V+VSG+P Sbjct: 188 NAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 263 TRDKMRRLIRRLDSEMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSG 322 +R ++ +I++LD + GN++V YLKY+KA DLV+VL +S T+ + K+ A+ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPV-AAL 306 Query: 323 REVVSIAASKHSNALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGV 382 + + I A +NALIVTA D+M L+ VI QLDIRR QV VEA+I EV + +N G+ Sbjct: 307 DKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGI 366 Query: 383 QWGSKDAGLMQFANGTQIPIGTLGAAISAAKPQKGSTVISENGATTINPDTNGDLST-LA 441 QW +K+AG+ QF N + +PI T A + +G +S+ LA Sbjct: 367 QWANKNAGMTQFTN-SGLPISTAIAG-------------------ANQYNKDGTVSSSLA 406 Query: 442 QLLSGFSGTAVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTG 501 LS F+G A G +G+W L+ A+ + + +++L+TPSI TLDN EA F VGQ+VPVLTG Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 502 STVGSNNSNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTS-----LDVV 556 S S N FNTVERK VGI LKV PQINEG++V + IEQEVS V S L Sbjct: 467 SQTTSG-DNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT 525 Query: 557 FGERKLKTTVLANDGELIVLGGLMDDQAGESVAKVPLLGDIPVIGNLFKSTADKKEKRNL 616 F R + VL GE +V+GGL+D ++ KVPLLGDIPVIG LF+ST+ K KRNL Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 617 MVFIRPTILRDGMAADGVSQRKYNYMRAEQIYR--DEQGLSLMPHTAQPILPAQNQALPP 674 M+FIRPT++RD S +Y Q + E +++ I P Q+ A Sbjct: 586 MLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFR 645 Query: 675 EVRAFLNA 682 +V A ++A Sbjct: 646 QVSAAIDA 653
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 119 bits (300), Expect = 2e-34 Identities = 71/284 (25%), Positives = 116/284 (40%), Gaps = 38/284 (13%) Query: 3 RGMFWLMLLIISAKMAYSLWRYFSFSAEYTAVSSSVN-KPLRADAKPFDKNDVQLVSQQN 61 R +F+L++L+ ++A WR A SSV P +A +P ND L Sbjct: 16 RILFYLLMLLFCQQLAMIFWR---IGLPDNAPVSSVQITPAQARQQPVTLNDFTL----- 67 Query: 62 WFGKY-QPVAAPV-KQPESAPVAETRLNVVLRGIAFG---ARPGVVIEEGGKQQVYLQGE 116 FG + A + + + + LN+ L G+ G +R +I + +Q E Sbjct: 68 -FGVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNE 126 Query: 117 RLGSHNAVIEEINRDHVMLRYQGKMERLSLAEEERPPVAVTSKKAASDEAKQAVAEPVVS 176 + +NA I I D V+L+YQG+ E L L +E + SD A Sbjct: 127 EVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQE---------DSGSDGVPGAQVN---- 173 Query: 177 APVEIPAAVRQALAKDPQKIFNYIQLTPVRKEG-IVGYAVKPGADRSLFDASGFREGDIA 235 Q + + +Y+ +P+ + + GY + PG F G ++ D+A Sbjct: 174 ---------EQLQQRASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMA 224 Query: 236 IALNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARYDISIAL 279 +ALN D D M ++ + + LTV R G R DI + Sbjct: 225 VALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 283 bits (726), Expect = 1e-97 Identities = 111/276 (40%), Positives = 151/276 (54%), Gaps = 12/276 (4%) Query: 31 LTMLFDVFQQYPAAMPILATVGGLIIGSFLNVVIWRYPIML-RQQMAEFHGETPSTQSKI 89 + +L ++ P L + L+IGSFLNVVI R PIML R+ AE+ + Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGV 60 Query: 90 -----SLALPRSHCPHCQQTIRVRDNIPLLSWLMLKGRCRDCQAKISKRYPLVELLTALA 144 +L +PRS CPHC I +NIPLLSWL L+GRCR CQA IS RYPLVELLTAL Sbjct: 61 DEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALL 120 Query: 145 FLLASLVWPESGWGLAVMILSAWLIAASIIDLDNQWLPDVFTQGVLWTGLIAAWAQQSPL 204 + ++ LA ++L+ L+A + IDLD LPD T +LW GL+ + Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNL-LGGFV 179 Query: 205 TLQDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGWVGPLSLPNVALIAS 264 +L DAV G + G++ +SL W ++ KE +G GD L AALG W+G +LP V L++S Sbjct: 180 SLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSS 239 Query: 265 CCGLIYAVI-----TKRGSTTLPFGPCLSLGGIATL 295 G + S +PFGP L++ G L Sbjct: 240 LVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIAL 275
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 48.0 bits (114), Expect = 1e-07 Identities = 29/107 (27%), Positives = 41/107 (38%), Gaps = 8/107 (7%) Query: 46 PEVKPDPTPTPEPTPEPTPDPEPTPDPTPD-PEPTPEPEPEPVPTKTGYLTLGGSQRVTG 104 V+P P P EP PEP P PEP + +P P+P+P+P P K ++ Sbjct: 64 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKK-------VEQPKR 116 Query: 105 ATCNGESSDGFTFTPGNTVSCVVGSTTIATFNTQSEAARSLRAVDKV 151 ES F + T AT + A RA+ + Sbjct: 117 DVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRN 163 Score = 41.1 bits (96), Expect = 2e-05 Identities = 14/87 (16%), Positives = 21/87 (24%), Gaps = 1/87 (1%) Query: 35 TPSVDSGSGTLPEVKPDPTPTPEPTPEPTPDPEPTPDPTPDPEPTPEPEPEPVPT-KTGY 93 P PE P+P E P+ + +PV + Sbjct: 69 PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASP 128 Query: 94 LTLGGSQRVTGATCNGESSDGFTFTPG 120 R T +T +S T Sbjct: 129 FENTAPARPTSSTATAATSKPVTSVAS 155 Score = 38.8 bits (90), Expect = 9e-05 Identities = 16/58 (27%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 31 SSSDTPSVDSGSGTLPEVKPDPTPTPEPTPEPTPDPEPTPDPTPDPEPTPEPEPEPVP 88 S + + + + P P P PEP +P P+PEP PEP E Sbjct: 36 SVHQVIELPAPAQPISVTMVAPADLEPP-QAVQPPPEPVVEPEPEPEPIPEPPKEAPV 92 Score = 36.9 bits (85), Expect = 4e-04 Identities = 16/46 (34%), Positives = 19/46 (41%) Query: 46 PEVKPDPTPTPEPTPEPTPDPEPTPDPTPDPEPTPEPEPEPVPTKT 91 P T EP +P P+P +PEP PEP PEP Sbjct: 46 PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP 91 Score = 36.1 bits (83), Expect = 6e-04 Identities = 17/40 (42%), Positives = 17/40 (42%) Query: 50 PDPTPTPEPTPEPTPDPEPTPDPTPDPEPTPEPEPEPVPT 89 P P T D EP P PEP EPEPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 32.7 bits (74), Expect = 0.002 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 112 VSVKNTSHCGALSYFAEMITH-KGLVAIVMTQTDTC 146 V VK+ S CG + AE T+ KG+ A M DTC Sbjct: 406 VVVKSCSDCGTCTSCAEATTYWKGVAATHMCVVDTC 441
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 6e-23 Identities = 30/129 (23%), Positives = 56/129 (43%) Query: 2 RILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRD 61 IL+ +DD I + LS+ G+ V + + + D V+ D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNG 121 +L ++ PVL+++A++ ++ GA DYL KPF L E+ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 QASNELRHG 130 + S Sbjct: 125 RPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 37/176 (21%), Positives = 60/176 (34%), Gaps = 29/176 (16%) Query: 284 DRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQANIDVRLTLNANG 343 +A ++ L L R SL ++ L D L +V+D Y + RL Sbjct: 191 TKAREMLTSLSELMRY-SLRYSNA-RQVSLADEL--TVVDSYLQLASIQFEDRLQFENQI 246 Query: 344 IKRTGQ----PLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADN----FIVRDNGPGVTPE 395 P+L+ LV N + + + PQG + + DN V + G Sbjct: 247 NPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN 306 Query: 396 ALARIGERFYRPPGQTATGSGLGLSIV-QRIAKLHDMNVEFG-NAEQGGFEAKVSW 449 T +G GL V +R+ L+ + + +QG A V Sbjct: 307 ---------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 688 bits (1777), Expect = 0.0 Identities = 233/878 (26%), Positives = 401/878 (45%), Gaps = 70/878 (7%) Query: 14 HAIKNALSG------VVCSLLFVLPVH--AVEFNVDMIDAEDRENIDISRFEKKGYIPPG 65 H K+ L+G V C+ P+ + FN + + + D+SRFE +PPG Sbjct: 17 HIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPG 76 Query: 66 RYLVRVQINKNMLPQTLILEWVKADNESGSLLCLTKENLTNFGLNTEFIESLQNIAGSEC 125 Y V + +N + + + D+E G + CLT+ L + GLNT + + +A C Sbjct: 77 TYRVDIYLNNGYMATRDV-TFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDAC 135 Query: 126 LDLSQR-QELTTRLDKATMILSLSVPQAWLKYQATNWTPPEFWDTGIAGFILDYNVYASQ 184 + L+ + T +LD L+L++PQA++ +A + PPE WD GI +L+YN + Sbjct: 136 VPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNS 195 Query: 185 YAPHHGDSTQNVSSYGTLGFNLGAWRLRSDYQYNQNFADGRSVNRDS-EFARTYLFRPIP 243 G ++ G N+GAWRLR + ++ N +D S +++ + T+L R I Sbjct: 196 VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDII 255 Query: 244 SWSSKFTMGQYDLSSNLYDTFHFTGASLESDESMLPPDLQGYAPQITGIAQTNAKVTVAQ 303 S+ T+G +++D +F GA L SD++MLP +G+AP I GIA+ A+VT+ Q Sbjct: 256 PLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQ 315 Query: 304 NGRVLYQTTVAPGPFTISDL-GQSFQGLLDVTVEEEDGRTSTFQVGSASIPYLTRKGQVR 362 NG +Y +TV PGPFTI+D+ G L VT++E DG T F V +S+P L R+G R Sbjct: 316 NGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTR 375 Query: 363 YKTSLGKPTSVGHNDINNPFFWTAEASWGWLNNVSLYGGGMFTADDYQAITTGIGFNLNQ 422 Y + G+ S P F+ + G ++YGG AD Y+A GIG N+ Sbjct: 376 YSITAGEYRSGNAQQE-KPRFFQSTLLHGLPAGWTIYGGTQL-ADRYRAFNFGIGKNMGA 433 Query: 423 FGSLSFDVTGADASLQQQNSGNLRGYSYRFNYAKHFESTGSQITFAGYRFSDKDYVSMSE 482 G+LS D+T A+++L G S RF Y K +G+ I GYR+S Y + ++ Sbjct: 434 LGALSVDMTQANSTLPDD--SQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFAD 491 Query: 483 YLSSRNGDESID--------------------NEKESYVISLNQYFETLELNSYLNVTRN 522 SR +I+ N++ +++ Q YL+ + Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT-STLYLSGSHQ 550 Query: 523 TYWDS-ASNTNYSVSVSKNFDIGDFKGISASLAVSRIR--WDDDEENQYYFSFSLPL--- 576 TYW + + + ++ F+ I+ +L+ S + W + + ++P Sbjct: 551 TYWGTSNVDEQFQAGLNTA-----FEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHW 605 Query: 577 --------QQNRNISYSMQRTGSSNTSQMISWYDS--SDRNNIWNISASATDDNIRDGEP 626 ++ + SYSM + + + Y + D N +++ + Sbjct: 606 LRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGS 665 Query: 627 TLRGSYQHYSPWGRLNINGSVQPNQYNSVTAGWYGSLTATRHGIALHDYSYGDNARMMVD 686 T + + +G NI S + + G G + A +G+ L ++ ++V Sbjct: 666 TGYATLNYRGGYGNANIGYSHS-DDIKQLYYGVSGGVLAHANGVTLGQPL--NDTVVLVK 722 Query: 687 TDGISGIEINSNRTV-TNGLGIAVIPSLSNYTTSMLRVNNNDLPEGVDVENSVIRTTLTQ 745 G ++ + V T+ G AV+P + Y + + ++ N L + VD++N+V T+ Sbjct: 723 APGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTR 782 Query: 746 GAIGYAKLNATTGYQIVGVIRQENGRFPPLGVNVTDKATGKDVGLVAEDGFVYLSGIQEN 805 GAI A+ A G +++ + N + P G VT + + G+VA++G VYLSG+ Sbjct: 783 GAIVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVTS-ESSQSSGIVADNGQVYLSGMPLA 840 Query: 806 STLHLTWGD---NTCEVT---PPNQSNISESAIILPCK 837 + + WG+ C PP + + C+ Sbjct: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.4 bits (120), Expect = 2e-08 Identities = 47/287 (16%), Positives = 92/287 (32%), Gaps = 16/287 (5%) Query: 197 PNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQ 256 N A+ + + E R A + + ++ E +QE+ + Sbjct: 999 TPNNIQAD-VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA---ENSKQESKTVEKN 1054 Query: 257 EQQVKTRTAEQNAKIAAFEAERRREAE-QTRILAERQIQETEIDREQAVRSRKVEAEREV 315 EQ TA+ + A EA+ +A QT +A+ + E + + VE E + Sbjct: 1055 EQDATETTAQN--REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 316 RIKEIEQQQVTEIANQTKSIAIAAKSEQ---QSQAEARANLALAEAVSAQQNVETTRQTA 372 +++ + Q+V ++ +Q +++ Q + E + + E S T Q A Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 373 EADRAKQVALIAAAQDAET------KAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGL 426 + + + + T T +E + R Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Query: 427 AEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKAI 473 A + ND V + TS L A ++ KA+ Sbjct: 1233 NVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAV 1279
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.0 bits (65), Expect = 0.029 Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 347 GVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRL 383 G FD + GH+ + +L D++ VAV + + + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPM 43
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.014 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 19 VLITGATGLVGGHLLRMLINEP 40 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 28.5 bits (63), Expect = 0.017 Identities = 30/144 (20%), Positives = 53/144 (36%), Gaps = 17/144 (11%) Query: 57 ALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVE 116 AL +I + + +A L D+ K +K D+ T+D YL G ++ Sbjct: 307 ALDLLVINKQQSNFQKEAHEIIFDLALDGADQTKEQL--IKTDEELGTDDEDFYLKGAMQ 364 Query: 117 ----VNALVPDSQLRRITT----------DNAQINLVTQDVTSEDLVTLYGTTFNSSGLK 162 VN + P + +T + + T +TSE Y T + K Sbjct: 365 NFSYVNYVSPLKVISDPSTGIVSSKKNNAEMKSKQMSTDQMTSEKEFDYYTETLKALLEK 424 Query: 163 M-RGNLRSKNAELIEKVRTSYEIQ 185 L +L+E ++ +Y I+ Sbjct: 425 EDSAELNENEKKLVETIKKAYTIE 448
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 7e-13 Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 4/115 (3%) Query: 528 VLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDI 587 +L+ +D V L + G V + G+ DLV+ D+ +PD D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 588 SRELTKRYPREDLPPLVALTA-NVLKDKQEYLNAGMDDVLSKPLSVPALTAMIKK 641 + K P P++ ++A N + G D L KP + L +I + Sbjct: 66 LPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.1 bits (143), Expect = 1e-11 Identities = 81/455 (17%), Positives = 158/455 (34%), Gaps = 46/455 (10%) Query: 40 LLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMV 99 + +++ + L ++ +F + +A ++ G + G + D+ G + ++ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 100 TSIVLFSAGTLACGFAPGYITMFI-ARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGF 158 I++ G++ + ++ I AR + G G A V PK R KA G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 159 LISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKA 218 + S ++G V + ++ W L I ++ II +L K + + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR--------- 194 Query: 219 PVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQ 278 +G I I++ + IV+VL L IF+ + + Sbjct: 195 ---------IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL---IFVKHIRK 242 Query: 279 STGK----RWPTGVMLMVVVLFAFLYSWPIQA---LLPTYLKTDLAYDPHTVANVLFFSG 331 T + M+ VL + + ++P +K + +V+ F G Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 332 -FGAAVGCCVGGFLGDWLGTRK-AYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQML 389 + +GG L D G + S + F + W + +++ F Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLET-TSWFMTIIIVFVLGG 361 Query: 390 GQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAP-ILGALIA-----QRL---- 439 ++ ++ + AG+ L I+G L++ QRL Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPME 421 Query: 440 -DLGTALAS---LSFSLTFVVILLIGLDMPSRVQR 470 D T L S L FS V+ L+ L++ QR Sbjct: 422 VDQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQR 456
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.5 bits (61), Expect = 0.026 Identities = 8/27 (29%), Positives = 16/27 (59%) Query: 127 IEADKSGTVKAILVESGQPVEFDEPLV 153 I+ ++ VK I+V+ G+ V + L+ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLL 125
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 27.4 bits (60), Expect = 0.014 Identities = 11/17 (64%), Positives = 12/17 (70%) Query: 13 DPNMSYQKLRWARKNEI 29 DPNM+ LRW R NEI Sbjct: 456 DPNMTNSGLRWYRVNEI 472
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 883 bits (2282), Expect = 0.0 Identities = 398/866 (45%), Positives = 570/866 (65%), Gaps = 28/866 (3%) Query: 19 KRVVPLLLVIMPACSIA--------GMRFNPAFLSGDTEAVADLSRFEKGMTYLPGSYEV 70 R+ + + AC+ A + FNP FL+ D +AVADLSRFE G PG+Y V Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRV 80 Query: 71 EVWVNDSPLLSRTVTFKADDANQ-LIPCLSLADLLSLGINKNALPEQALASSENSCLDLR 129 ++++N+ + +R VTF D+ Q ++PCL+ A L S+G+N ++ L + +++C+ L Sbjct: 81 DIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA-DDACVPLT 139 Query: 130 IWFPDVHYMPELDAQRLKLTFPQAIIKRDARGYIPPEQWDNGITAFLLNYDFSGN--NDR 187 D ++ QRL LT PQA + ARGYIPPE WD GI A LLNY+FSGN +R Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 188 GDYSSNNYYLNLRAGINIGAWRFRDYSTWSR-----GSNSAGKLEHISSTLQRVIIPFRS 242 +S+ YLNL++G+NIGAWR RD +TWS S S K +HI++ L+R IIP RS Sbjct: 200 IGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRS 259 Query: 243 ELTLGDTWSSSDVFDSVSIRGIKLESDENMLPDSQSGFAPTVRGIAKSRAQVTIKQNGYV 302 LTLGD ++ D+FD ++ RG +L SD+NMLPDSQ GFAP + GIA+ AQVTIKQNGY Sbjct: 260 RLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYD 319 Query: 303 IYQTYMPPGPFEISDLNPTSSAGDLEVTIKESDNSETVYTVPYAAVPILQREGHSKYSTT 362 IY + +PPGPF I+D+ ++GDL+VTIKE+D S ++TVPY++VP+LQREGH++YS T Sbjct: 320 IYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSIT 379 Query: 363 VGQYRSNSYNQKSPYIFQGELIWGLPWDITAYGGAQFSEDYRALALGLGLNLGVFGATSF 422 G+YRS + Q+ P FQ L+ GLP T YGG Q ++ YRA G+G N+G GA S Sbjct: 380 AGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSV 439 Query: 423 DVTQANSSLVDGSKHQGQSYRFLYSKSLVQTGTAFHIIGYRYSTQGFYTLSDTTYQQMSG 482 D+TQANS+L D S+H GQS RFLY+KSL ++GT ++GYRYST G++ +DTTY +M+G Sbjct: 440 DMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNG 499 Query: 483 TVVDPKTLDDKDYVYNWNDFYNLRYSKRGKFQASVSQPFGNYGSMYLSASQQTYWNTDKK 542 ++ + + + D+YNL Y+KRGK Q +V+Q G ++YLS S QTYW T Sbjct: 500 YNIETQDGVIQVKPK-FTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNV 558 Query: 543 DSLYQVGYNTSIKGIYLNVAWNYSKSPGTN-ADKIVSLNVSLPISNWLSSTNDGRSSSNA 601 D +Q G NT+ + I ++++ +K+ D++++LNV++P S+WL S D +S Sbjct: 559 DEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRS--DSKSQWRH 616 Query: 602 MTATYGYSQDNHGQVNQYTGVSGSLLEQHNLSYNIQHGFANQDNSSSGSVG---VNYRGA 658 +A+Y S D +G++ GV G+LLE +NLSY++Q G+A + +SGS G +NYRG Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 659 YGSLNSAYSYDNEGNQQINYGISGALVVHENGLTLSQPLGETNVLIKAPGANNVDVQRGT 718 YG+ N YS+ + +Q+ YG+SG ++ H NG+TL QPL +T VL+KAPGA + V+ T Sbjct: 677 YGNANIGYSHSD-DIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQT 735 Query: 719 GISTDWRGYAVVPYATEYRRNNISLDPMSMNMHTELDITSTEVIPGKGALVRAEFAAHIG 778 G+ TDWRGYAV+PYATEYR N ++LD ++ + +LD V+P +GA+VRAEF A +G Sbjct: 736 GVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVG 795 Query: 779 IRGLFTVRYRNKSVPFGATASAQIKNSSQITGIVGDNGQLYLSGLPLEGVINIQWGDGVQ 838 I+ L T+ + NK +PFGA +++ SSQ +GIV DNGQ+YLSG+PL G + ++WG+ Sbjct: 796 IKLLMTLTHNNKPLPFGAMVTSE---SSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 839 QKCQANYKLPETELDNPVSYATLECR 864 C ANY+LP ++ + ECR Sbjct: 853 AHCVANYQLPPESQQQLLTQLSAECR 878
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 4e-05 Identities = 20/92 (21%), Positives = 32/92 (34%), Gaps = 16/92 (17%) Query: 55 VACIDGIVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMID------MCD 108 + ++ +G + I + + D + D R K GV +AL+ + I+ C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKFGFEIEG 140 L I N A Y K F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 32.0 bits (72), Expect = 0.005 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 13/80 (16%) Query: 272 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMQKYGF-GSADAMQIMAEAEKYA 330 R P+ G+ R + SMPPP G H +I N+ F Q G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNL--KFFKQFDGYVGGQTAWGILSELEKGR 133 Query: 331 YADRSEYLGDPDFVKVPWQA 350 Y P F WQ+ Sbjct: 134 Y---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 28.4 bits (63), Expect = 0.020 Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.042 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTTGDI 61 +V+ G G GKSTL+ + GL+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 3e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPKQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.8 bits (121), Expect = 1e-08 Identities = 43/208 (20%), Positives = 67/208 (32%), Gaps = 21/208 (10%) Query: 20 QTPEK-ETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAANVVEVTEQV 78 TP + +V + EEI + E T AE + VE EQ Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 79 AESEKAQ---------------PEAEVVAQPESVVEETPEPVAIEREELPLPEDVNAEAV 123 A AQ + VAQ S +ET E + E E Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET- 1116 Query: 124 SPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALAAEVAEEA-VMVVSPSEEEQPVE 182 E E V + ++E ++ EP + +E + ++ EQP + Sbjct: 1117 ---EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 183 EIAQEQEKPTKEGFFARLKRSLLKTKEN 210 E + E+P E S+++ EN Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Score = 47.0 bits (111), Expect = 2e-07 Identities = 36/179 (20%), Positives = 61/179 (34%), Gaps = 9/179 (5%) Query: 19 EQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAANVVEVTEQV 78 TP + TE E E + A+E + + A EV + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 79 AESEKAQPEAEVVAQPESVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIV 138 +E+++ Q + +V +E E +E E+ V ++ VSP++ Q+E + Sbjct: 1090 SETKETQTTE--TKETATVEKE--EKAKVETEKTQEVPKVTSQ-VSPKQEQSETVQPQ-A 1143 Query: 139 EAAEEEAAKEEITDEEPEAQALAAEVA---EEAVMVVSPSEEEQPVEEIAQEQEKPTKE 194 E A E I + + + A E + V P E V E P Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT 1202 Score = 42.0 bits (98), Expect = 6e-06 Identities = 28/156 (17%), Positives = 45/156 (28%), Gaps = 14/156 (8%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASE------HAVEEQPQAHTEAEAETFAAN 70 Q +T E T + E+ VE + P S+ + QPQA E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 71 VVEVTEQVAESEKAQPEAEVVAQPESVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQA 130 ++ ++ QP E + E V E+ V + PE+ P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQPTVNSE 1214 Query: 131 EAETVEI-------VEAAEEEAAKEEITDEEPEAQA 159 + + E A D A Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALC 1250 Score = 40.8 bits (95), Expect = 1e-05 Identities = 25/176 (14%), Positives = 54/176 (30%), Gaps = 2/176 (1%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAEAETFAANVVEVTE 76 +E E ++ V+ E E + +E E +A+ EV + Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 77 QVAESEKAQPEAEVVAQPESVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETVE 136 ++ Q ++E V QP++ +P + +E + A+ P + + Sbjct: 1125 VTSQVSPKQEQSETV-QPQAEPARENDPT-VNIKEPQSQTNTTADTEQPAKETSSNVEQP 1182 Query: 137 IVEAAEEEAAKEEITDEEPEAQALAAEVAEEAVMVVSPSEEEQPVEEIAQEQEKPT 192 + E+ + + E A + + V + E T Sbjct: 1183 VTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 53.3 bits (128), Expect = 8e-10 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 13 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 70 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 129 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 187 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 188 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 240 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 241 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 296 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 297 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 355 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 356 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 389 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>BORPETOXINB#Bordetella pertussis toxin B subunit signature. Length = 226 Score = 27.7 bits (61), Expect = 0.048 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 10/77 (12%) Query: 204 GQRHVTWARLRGLSDKQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVG- 262 R +T A LRG D Q RH+ R S+ + G ++G GG +I++ PG Sbjct: 53 KTRALTVAELRGSGDLQEYLRHVTRGWSIFALYD-GTYLGGEYGG--VIKD--GTPGGAF 107 Query: 263 ----RYAVSAIFNRDYP 275 + + N P Sbjct: 108 DLKTTFCIMTTRNTGQP 124
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.008 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLALKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.029 Identities = 10/23 (43%), Positives = 13/23 (56%), Gaps = 1/23 (4%) Query: 28 EIVAIL-GPNGAGKSTLLRQLTG 49 + +L G G GKSTL+ L G Sbjct: 596 DYSVVLEGTGGIGKSTLINTLVG 618
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 58.3 bits (141), Expect = 5e-11 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 18/147 (12%) Query: 3 IATAGHVDHGKTTLLQAI---TGV------------NADRLPEEKKRGMTIDLGYAYWPQ 47 I HVD GKTTL +++ +G D E++RG+TI G + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 48 PDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLTGNPML 107 + +V ID PGH FL+ + + +D A+L+++ DGV AQTR L+ G P + Sbjct: 66 ENTKV-NIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTI 124 Query: 108 TVALTKADRVDEARVDEVERQVKEVLR 134 + K D+ + V + +KE L Sbjct: 125 -FFINKIDQNG-IDLSTVYQDIKEKLS 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.8 bits (150), Expect = 2e-12 Identities = 55/314 (17%), Positives = 102/314 (32%), Gaps = 82/314 (26%) Query: 66 ITLQVTGIVTEVTDKNNQLIQKGEVLFKLDPVR------------YQARVD--RLQA--- 108 I IV E+ K + ++KG+VL KL + QAR++ R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 109 ------------------------DLMTATHNIK----TLRAQLTEAQANTTQVSAERDR 140 +++ T IK T + Q + + N + AER Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 141 LFKNYQRY----------LKGSQAAVNPFS---------ERDIDDARQNF---LAQDALV 178 + RY L + ++ + E +A +Q + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 179 KGSVAE----QAQIQSQLDSMVNGE----QSQIVSLRAQLTEAKYNLEQTVIRAPSNGYV 230 + + + + + + I L +L + + + +VIRAP + V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 231 TQVLIR-PGTYAAALPLRPVMVFIPEQKRQIV-AQFRQNSLLRLKPGDDAEVVFNALPGQ 288 Q+ + G +MV +PE V A + + + G +A + A P Sbjct: 339 QQLKVHTEGGVVT--TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 289 VFH---GKLTSILP 299 + GK+ +I Sbjct: 397 RYGYLVGKVKNINL 410
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 62.5 bits (152), Expect = 4e-14 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 1506 ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGV-SMVSANGRWVYKLQ 1564 +L G+A+ A++ L Q G + S G Y ++A+A+GV S ++ + Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 1565 GSTNSQGEYSAALGAGIQW 1583 +T + G S G ++ Sbjct: 62 FNTYN-GGMSYGASVGYEF 79
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (260), Expect = 7e-28 Identities = 77/348 (22%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLDI 47 +VTG AGFIG ++ K L + G ++ +DNL D +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.3 bits (66), Expect = 0.032 Identities = 18/55 (32%), Positives = 22/55 (40%), Gaps = 15/55 (27%) Query: 74 GHIELGKWADLVILAPA----------TADLIARVAAGMANDLVSTICLATPAPV 118 G +E+GK ADLV+ PA IA G N + TP PV Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNA-----SIPTPQPV 473
>SECA#SecA protein signature. Length = 901 Score = 39.9 bits (93), Expect = 4e-05 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 18/129 (13%) Query: 244 NLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARVVAEIERDM-ALDVPMM 302 LS L+ F A+ L + L+N + A A R ++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 303 ---RLVQGDV-----GSGKTLVAALAA-LRAVAHGKQVALMAPTELLAEQHANNFRNWFA 353 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R F Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 354 PLGIEVGWL 362 LG+ VG Sbjct: 149 FLGLTVGIN 157
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 34.1 bits (78), Expect = 0.001 Identities = 79/491 (16%), Positives = 168/491 (34%), Gaps = 73/491 (14%) Query: 7 RQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRLLEQWL-GQWRINVEKRAGAGVM 65 + +L+ + I +A ++ + L + + ++KR M Sbjct: 45 SKCQLVVLFF-KTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKR-----M 98 Query: 66 LSAENIADLLHLDHLLVAECEEIDGVMNNARRVKIASQLLSETPNETSISKLSERYFISG 125 + H ++ + + ++ +++ + L+ + ++ + +F+S Sbjct: 99 I-------SCQFTHP--SKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSN 149 Query: 126 ASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEGQVRQAMALLINGIINHNEPQGVVYS 185 +S + L L L S I G E ++R +ALL G+ Sbjct: 150 SSAYRMREALIPLLRNFELKL----SKNKIVGEEYRIRYLIALL-------YSKFGIKVY 198 Query: 186 RLDPGSYKALVHYFGEEEVLFVQSLLLDMENELSWSLGEPYYVNIFTHILIMMYRNTHGN 245 L K ++H F L S L LS E + F IL+ + H Sbjct: 199 DLTQQD-KNIIHSF-----LSHSSTHLKTSPWLS----ESFS---FYDILLALSWKRHQF 245 Query: 246 ALSREEDQTRQYDENIF---NVASQMIHKIEQRIAHTLPDDEVWFIYQ-YIISSGVAIDG 301 +++ + + Q + +F ++ IE ++ ++Y YI ++ Sbjct: 246 SVTIPQTRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASL 305 Query: 302 Q---KDVSIISHMQASNEA-RLITWRLITVFSDIVD---------CDFSEDSALYDGLLV 348 Q + + + N+ RL+ +IT+ ++ + FS+ S L++ L Sbjct: 306 QWTPEHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSK-SFLFN--LQ 362 Query: 349 HIKPLINRLNYRIHIRNPLLEDIKAELADVWRLTQYVVNQVFKTWGENAVSEDEVGYLTV 408 H P N + N L + + W + K G+ ++ Sbjct: 363 HFIPETNLFVSPYYKGNQKLYTSLKLIVEEW---------MAKLPGKRYLNHKHFHLFCH 413 Query: 409 HFQAAMERQIARKRVLLVCSTGIGTSHLLKSRILRAFPEWTI---VDVISAANLSQVLPD 465 + + + V+ V S I +HLL R F + +I + N+ Q+ Sbjct: 414 YVEQILRNIQPPLVVVFVASNFI-NAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDL 472 Query: 466 NIELIISTINL 476 +L+I+ L Sbjct: 473 KPDLVITHSQL 483
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 3e-05 Identities = 34/208 (16%), Positives = 72/208 (34%), Gaps = 13/208 (6%) Query: 33 IIVEFLPVSLLTP----MAQDLGISEGVA---GQSVTVTAFVAMFASLFITQTIQATDRR 85 + ++ + + L+ P + +DL S V G + + A + + + RR Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 86 YVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 145 V+++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 146 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAAMG----VLCIFWIIKSLPSLPGE 201 + +V LG +G F AAAA+ + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 202 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 229 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 1e-04 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG-AEYAD---------APA 71 V+R D +I N ILD + G + I +K IA +G A D P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 1e-05 Identities = 64/408 (15%), Positives = 135/408 (33%), Gaps = 60/408 (14%) Query: 30 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 87 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 88 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 144 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 145 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLC 203 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 204 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 263 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 264 YVV-----RAAINDWGN-----------LYMSEMLGVDLVTANTAVTMFELGGFIGALVA 307 +++ R + + + + + V ++ + + A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 308 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 366 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 367 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 396 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 2e-05 Identities = 28/142 (19%), Positives = 57/142 (40%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 424 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----DASAVTLQGWQQDERLMLVIEDDGSGLPPDSGQ-HGFGLTGMRERVTALG 478 +KH + L+G + + + L +E+ GS ++ + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLTISCLHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.0 bits (148), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.048 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 8e-04 Identities = 40/196 (20%), Positives = 62/196 (31%), Gaps = 51/196 (26%) Query: 180 KHALEHPKPTNAVSRALQHDLSDVVGQEQG----KRGLEITAAGGHNLLLIGPPGTGKTM 235 AL PK + D +VG+ R L L++ G GTGK + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 236 LASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSA--------SLTA 287 +A ++ R PF + + +A L Sbjct: 176 VARALHDYGK-------------------------RRNGPFVAINMAAIPRDLIESELFG 210 Query: 288 MVGG---GAIP-GPGEISLAHNGVLFLDEL----PEFERRTLDALREPIESGQIHLSRTR 339 G GA G A G LFLDE+ + + R L L++ G+ Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQ----GEYT--TVG 264 Query: 340 AKITYPARFQLVAAMN 355 + + ++VAA N Sbjct: 265 GRTPIRSDVRIVAATN 280
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.002 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVAEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 602 bits (1553), Expect = 0.0 Identities = 206/478 (43%), Positives = 299/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESNVPESTSHMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.0 bits (98), Expect = 2e-06 Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVARA 232 T E++ Q T T+Q V + + + A+TQ + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 357 bits (916), Expect = e-127 Identities = 171/262 (65%), Positives = 204/262 (77%), Gaps = 6/262 (2%) Query: 30 WLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGVGSHYDVGIW 89 W HQS+NV+G +RFGP++ ND Y EY +KDWFDFYGY+D P FFG G+ GIW Sbjct: 34 WWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYIDAPVFFG-GNSTAKGIW 92 Query: 90 DEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTD 149 ++GSPLF EIEPRFSIDKLT +L+FGPFKEW+ ANNY+YDMG N S QSTWYMGLGTD Sbjct: 93 NKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNDSQEQSTWYMGLGTD 152 Query: 150 IDTGLPIKLSANIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTNLFGGRLVYNSFTNFD 209 IDTGLP+ LS N+YAKYQWQNYGA+NENEWDGYRFK+KY +PLT+L+GG L Y FTNFD Sbjct: 153 IDTGLPMSLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFD 212 Query: 210 FGSDLADKSHNN-----KRTSNAIASSHILSLLYEHWKFAFTLRYFHNGGQWNAGEKVNF 264 +GSDL D + + RTSN+IASSHIL+L Y HW ++ RYFHNGGQW K+NF Sbjct: 213 WGSDLGDDNFYDLNGKHARTSNSIASSHILALNYAHWHYSIVARYFHNGGQWADDAKLNF 272 Query: 265 GDGPFELKNTGWGTYTTIGYQF 286 GDGPF +++TGWG Y +GY F Sbjct: 273 GDGPFSVRSTGWGGYFVVGYNF 294
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.019 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 18 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 49 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.007 Identities = 6/21 (28%), Positives = 12/21 (57%) Query: 179 FGNLDDPSSEISQLLRQKPTY 199 GNL++P+ ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 50 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 109 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 110 AEMTELSTNVKRHDAHRFYLREGY 133 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.019 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 69 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 122 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 123 TTVGWVSQFL 132 V F Sbjct: 656 ADAEAVKAFF 665
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 2e-15 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAVTIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ +T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 8e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.4 bits (58), Expect = 0.012 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.028 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.4 bits (84), Expect = 8e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>PF06704#DspF/AvrF protein Length = 129 Score = 25.2 bits (55), Expect = 0.047 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 6/85 (7%) Query: 28 RTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAA-GEQVVPAS 86 + + + +S + SL A Q+GV A L+ Q E ++ + E V+ Sbjct: 2 NNSPTDFSRLIKSLGAQLGTSLTA-QNGVCA----LYDSQDNEAAVIEMPDHSEMVIFHC 56 Query: 87 ELAAAMKQIKELQRLLNKTPDVSRL 111 + + + +LQ+LL+ DV+R+ Sbjct: 57 RVGRSPDRAADLQKLLSLNFDVARM 81
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 411 bits (1057), Expect = e-137 Identities = 202/339 (59%), Positives = 270/339 (79%), Gaps = 1/339 (0%) Query: 1 MIQARNQLLAEAAKSPA-LNMVRPNGMNDEPQFQILIDDEKVQAFKLSMSDVDNIMSAAW 59 + QARNQLL AA+ PA L VRPNG+ D QF++ +D EK QA +S+SD++ +S A Sbjct: 694 LTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTAL 753 Query: 60 GSMYVNDFNDRGRVKKVYIQGEPGSRISPQDFDKWYVRNSDGDMVSFASFATGKWIYGSP 119 G YVNDF DRGRVKK+Y+Q + R+ P+D DK YVR+++G+MV F++F T W+YGSP Sbjct: 754 GGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 813 Query: 120 KLEQYNGISAVEILGEPAPGYSSGDAMKAIEDIAARLPEGFHISWTGLSFEERLSGSQAP 179 +LE+YNG+ ++EI GE APG SSGDAM +E++A++LP G WTG+S++ERLSG+QAP Sbjct: 814 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAP 873 Query: 180 ALYALSLLIVFLCLAALYESWSIPFSVMLVVPLGVLGAVCATLLRGLGNDVFFQVGLLTT 239 AL A+S ++VFLCLAALYESWSIP SVMLVVPLG++G + A L NDV+F VGLLTT Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 240 IGLSAKNAILIVEFARELHEKEGLSIKEAAVEAARVRLRPIIMTSLAFVMGVIPLAVSTG 299 IGLSAKNAILIVEFA++L EKEG + EA + A R+RLRPI+MTSLAF++GV+PLA+S G Sbjct: 934 IGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNG 993 Query: 300 ASSGSKHAIGTGVVGGMITATILAIFYIPLFYMLIAGFF 338 A SG+++A+G GV+GGM++AT+LAIF++P+F+++I F Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCF 1032 Score = 77.2 bits (190), Expect = 1e-17 Identities = 64/322 (19%), Positives = 125/322 (38%), Gaps = 21/322 (6%) Query: 29 EPQFQILIDDEKVQAFKLSMSDVDNIMSAA----WGSMYVNDFNDRGRVKKVYIQGEPGS 84 + +I +D + + +KL+ DV N + G+ I + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ-TR 239 Query: 85 RISPQDFDKWYVR-NSDGDMVSFASFAT---GKWIYGSPKLEQYNGISAVEILGEPAPGY 140 +P++F K +R NSDG +V A G Y + + NG A + + A G Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV--IARINGKPAAGLGIKLATGA 297 Query: 141 SSGDAMKAI----EDIAARLPEGFHISW---TGLSFEERLSGSQAPALYALSLLIVFLCL 193 ++ D KAI ++ P+G + + T + + A+ ++VFL + Sbjct: 298 NALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI--MLVFLVM 355 Query: 194 AALYESWSIPFSVMLVVPLGVLGAVCATLLRGLGNDVFFQVGLLTTIGLSAKNAILIVEF 253 ++ + VP+ +LG G + G++ IGL +AI++VE Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 254 ARELHEKEGLSIKEAAVEAARVRLRPIIMTSLAFVMGVIPLAVSTGASSGSKHAIGTGVV 313 + ++ L KEA ++ ++ ++ IP+A G++ +V Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 314 GGMITATILAIFYIP-LFYMLI 334 M + ++A+ P L L+ Sbjct: 476 SAMALSVLVALILTPALCATLL 497
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.0 bits (171), Expect = 4e-18 Identities = 33/63 (52%), Positives = 41/63 (65%) Query: 10 RHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFNEKKDLLRQV 69 R TK A+ETR+ ILDVA F + G S T+L IA AG TRGAIYW+F +K DL ++ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 IER 72 E Sbjct: 63 WEL 65
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 6e-12 Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 3/139 (2%) Query: 3 TIVIVEDEPIELESLRQIISQCVENAAIHEASTGKKAIHLIDQLSQIDMILVDINIPLPN 62 TI++ +D+ L Q +S+ + S I D+++ D+ +P N Sbjct: 5 TILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMPDEN 61 Query: 63 GKQVIEYLKKKNSDTKIIVITANDDFDIVRSMYNLKVDDYLLKPVKKCILTDTIKKTLAF 122 ++ +KK D ++V++A + F DYL KP L I + LA Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 DEGENEKSRALKQKVFAMI 141 + K Q ++ Sbjct: 122 PKRRPSKLEDDSQDGMPLV 140
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 53.1 bits (127), Expect = 4e-09 Identities = 50/312 (16%), Positives = 106/312 (33%), Gaps = 18/312 (5%) Query: 121 SRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDS 180 + ++ QERA + N L + +D ++ LT L+ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE---ELSNAKEKLRKND 105 Query: 181 ARLKALVDEL-ELAQLSANNRQELARLRSELAEKES--QQLDAYLQALRNQLNSQRQQEA 237 L ++ EL A+ + L + + + L+A AL + + ++ Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKAL 164 Query: 238 ERALESTEQLAESSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVR 297 E A+ + + L + A EL AL +++ + ++ + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 298 QALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQ 357 L + L + A A++ L + L+ A+L + Sbjct: 225 ARKADLEKA---LEGAMNFSTADSAKIKTLEA--EKAALEARQAELEKALEGAMNFSTAD 279 Query: 358 PLLRQIHQADGQPLTAE------QNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSN 411 + +A+ L AE Q+++L A ++ R L++ + L E KL+ N Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 412 GQLEDALKEVNE 423 E + + + Sbjct: 340 KISEASRQSLRR 351 Score = 40.4 bits (94), Expect = 4e-05 Identities = 52/257 (20%), Positives = 93/257 (36%), Gaps = 59/257 (22%) Query: 20 ATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLERIKQYQEVIDNYPKL 79 A A + + LE A A ++ L++ ALE R+ LE+ + Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM------NF 275 Query: 80 SATLRAQLNNMRDEPRSVSPGMSNDALNQEILQISS--QLLDKSRQAQQEQERAREIADS 137 S A++ + E AL E + Q+L+ +RQ+ + A Sbjct: 276 STADSAKIKTLEAE---------KAALEAEKADLEHQSQVLNANRQSLRRDLDA------ 320 Query: 138 LNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSA 197 +R ++E L N+ + QS L A Sbjct: 321 ----------SREAKKQLEAEHQKL---EEQNKISEASRQSLRRDLDAS----------- 356 Query: 198 NNRQELARLRSEL--AEKESQQLDAYLQALRNQLNSQRQQEAERALESTEQLAESSADLP 255 R+ +L +E E++++ +A Q+LR L++ R EA++ +E + A S Sbjct: 357 --REAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR--EAKKQVEKALEEANSKLA-- 410 Query: 256 KDIVAQFKINRELSAAL 272 A K+N+EL + Sbjct: 411 ----ALEKLNKELEESK 423
>SECA#SecA protein signature. Length = 901 Score = 31.8 bits (72), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 259 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLDDFEPRIDRDEENK-PIRV 317 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 318 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 377 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 378 SLQVRMPIVDWRRLCKQEPALIDY 401 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.027 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 179 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 232 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 145 bits (366), Expect = 1e-44 Identities = 86/256 (33%), Positives = 133/256 (51%), Gaps = 8/256 (3%) Query: 7 LAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLNQEGIQAVAAPFN 66 + GK ITG+AQGIG +A L GA I D E+ E V L E A A P + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQ 126 V ID IE+++GPID+LVN AG+ R ++EW +VN T VF S+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 AVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGI 186 +V+++M++R++G ++ + S + + R ++ YA+SK A M T+ + +ELA +NI+ N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 APGYFKTEMTKALVEDE--------AFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDF 238 +PG +T+M +L DE P + P ++ A +FL S + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 239 VNGHLLFVDGGMLVAV 254 + H L VDGG + V Sbjct: 246 ITMHNLCVDGGATLGV 261
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 58/324 (17%), Positives = 106/324 (32%), Gaps = 25/324 (7%) Query: 39 TGATNAELGFLMTAYGLVNFLLYLPGGWAADRFSARKLMTFSLISTGISGFYYATFPSYT 98 + A G L+ Y L+ F G +DRF R ++ SL + AT P Sbjct: 38 SNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW 97 Query: 99 MICLLHALWAVTTVFTFWAVCVRIIRTLGTSEEQGRLYGYWFLGKGLTSIVLGFLSVPVF 158 ++ + + +T T AV I + +E+ R +G+ + G ++ PV Sbjct: 98 VLYIGRIVAGITGA-TG-AVAGAYIADITDGDERARHFGF--MS---ACFGFGMVAGPVL 150 Query: 159 AKFGEGVDGLRATIIFYSVVTILAGVLAWFVCQDETHSEDKANFRLADMAF-----VLKM 213 G A + + L + F+ + E + R A M Sbjct: 151 GGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM 209 Query: 214 PTVWLAGVVTFCMWSI-YIGFGMVTPYLTQILHMGESEVAVASILRAYVLFAMGGLIGGQ 272 V V F M + + + + H + + ++ + L Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGIS----LAAFGILHSLAQAM 265 Query: 273 LADRCASRTRFMIYAFIGMIVFTTVYFFLP--GESRYVTIALANMVALGVFIYSANAVFF 330 + A+R +GMI T Y L + + + G+ + + A+ Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLS 325 Query: 331 SIIDEVRIPAKVTGTAAGLISLLT 354 +DE R G G ++ LT Sbjct: 326 RQVDEER-----QGQLQGSLAALT 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 223 bits (570), Expect = 8e-68 Identities = 81/355 (22%), Positives = 156/355 (43%), Gaps = 41/355 (11%) Query: 327 RKIAQQQISTNANFTFDSLHAASGGMKQVLLIARRAIKSISPILINGEEGVGKLSLAMAI 386 K ++ ++ L S M+++ + R +++ ++I GE G GK +A A+ Sbjct: 122 PKRRPSKLEDDSQ-DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 387 HNESEQRDGPFISVDCQMLSPENILHELLGSDVG-------PSPSKFELAHNGTLYLDKV 439 H+ ++R+GPF++++ + + I EL G + G S +FE A GTL+LD++ Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 440 EYLSGEVQSVLLKVLKTGLVTRSDSHRLIPVRFRLITCTSSSLREYVQQGAFSRQLYYEI 499 + + Q+ LL+VL+ G T I R++ T+ L++ + QG F LYY + Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 500 SMNEIEIPPLRKRREALKQMIDDIIDKYQERTRKKMTITPDANSVLLEYRWPGNISEFKN 559 ++ + +PPLR R E + ++ + + ++ +A ++ + WPGN+ E +N Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 560 RMEKVFINCNRLVLGLENIPLDIRQN-----NSSGDDDIPHLT----------------- 597 + ++ + V+ E I ++R L+ Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 598 -----------SLAELEMQAIEHTCRVCEWNLTKAAEVLKIGRTTLWRKLKIYNL 641 LAE+E I N KAA++L + R TL +K++ + Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 54.6 bits (131), Expect = 4e-12 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 62 DEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFN 121 A + +IAV DY+++G+G ALL I+ ++ L LE + N +A Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 122 EATIRRNYYPTTDG-REDAI 140 + Y E AI Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 27.2 bits (60), Expect = 0.038 Identities = 11/47 (23%), Positives = 24/47 (51%), Gaps = 3/47 (6%) Query: 76 AVAQSAGGV---FVSLPEIEEVENADINQRLLEVIEQIGSYSKQIRS 119 A+ + G+ F + + ++ +N + ++QI +Y+KQI S Sbjct: 131 ALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIAS 177
>cloacin#Cloacin signature. Length = 551 Score = 41.6 bits (97), Expect = 1e-05 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 4/142 (2%) Query: 522 DQQRLNDLQEKKRQKDLQDAK--EQAERNYQEQQKRRNAENAALNRMNETEAARHQREIA 579 DQ + +E +RQ++ E AERNY+ + N N + R E +A Q + Sbjct: 294 DQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNS 353 Query: 580 RINAMQYADQAVRDA-AIQRENERYEKALASGKKKTRETRNDEATRLLLQYSQQQAQVEG 638 R + + A++ + DA A ++ R+ +G + + +A R + +QA + Sbjct: 354 RKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDA 413 Query: 639 QIAAARQSAGIATERMTEAHKQ 660 A + A A E+ K+ Sbjct: 414 -AAKEKSDADAALSSAMESRKK 434
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 141 bits (357), Expect = 4e-45 Identities = 68/202 (33%), Positives = 106/202 (52%), Gaps = 34/202 (16%) Query: 1 MRK-VCAAILSAAICLAVSGAPAWASEHQSTLSAGYLHASTNVPG-SDDLNGINVKYRYE 58 M+K C + L+A LA + + A+ ST++ GY A ++ G + + G N+KYRYE Sbjct: 1 MKKIACLSALAA--VLAFTAGTSVAA--TSTVTGGY--AQSDAQGQMNKMGGFNLKYRYE 54 Query: 59 FTDT-LGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMA 117 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + Sbjct: 55 EDNSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVV 106 Query: 118 GVAYSRVSTFSGDYLRVTDNKGKKHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIA 177 GV Y + T T+ KHD S+ ++GAG+QFNP E+VA+D + Sbjct: 107 GVGYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFS 149 Query: 178 YEGSGSGDWRTDGFIVGVGYKF 199 YE S +I GVGY+F Sbjct: 150 YEQSRIRSVDVGTWIAGVGYRF 171
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.4 bits (107), Expect = 9e-07 Identities = 38/217 (17%), Positives = 75/217 (34%), Gaps = 12/217 (5%) Query: 114 EEAARNAEAASQSAAAAKKSETAAASSKNAAKTSETNAANSAQAAASSQTASANSATAAK 173 E + E ++ + K E + A E + + + S +A++ AK Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 174 KSETNAKNSETAAKTSETNAK-----SSQTAAKTSETNAKASETAAKNSQVAAAQSESAA 228 ++ +N + T + T T + T A T T S KN + +S Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Query: 229 AGSATSAAGSATAAANSQKAAKTSETNAKSSQTAAKTSETNAKASETAAKNSQDAAAQSE 288 AT+++ + A ++ TNA S AK + +Q E Sbjct: 1234 VEPATTSSNDRSTVA--LCDLTSTNTNAVLSDARAKAQFVALNVGKAV----SQHISQLE 1287 Query: 289 SAAAGSASAAAASATASANSQKAAKTSETNAKTSETA 325 G S T+ + +++ ++K+++T Sbjct: 1288 MNNEG-QYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQ 1323 Score = 42.4 bits (99), Expect = 8e-06 Identities = 29/159 (18%), Positives = 49/159 (30%), Gaps = 14/159 (8%) Query: 211 ETAAKNSQVAAAQSESAAAGSA--TSAAGSATAAANSQKAAKTSETNAKSSQTAAKTSET 268 E +N V + A S + A +A A S+T +E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 269 NAKASETAAKNSQDA------------AAQSESAAAGSASAAAASATASANSQKAAKTSE 316 + + S+T KN QDA A+S A + A S + + +Q Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 317 TNAKTSETAAANSAKASAASQTAAKASEDAAREYASQAA 355 + E A + K + ++ S + Q Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.029 Identities = 17/68 (25%), Positives = 25/68 (36%), Gaps = 6/68 (8%) Query: 4 PLFLIGPRGCGKTTVGMALADSLNRRFVDTDLWL----QSQLNMTVAEIVEREEWAGFRA 59 + L G G GK+T+ L F DT + S + E E FR Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL--DFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRR 655 Query: 60 RETAALEA 67 + A++A Sbjct: 656 ADAEAVKA 663
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.4 bits (66), Expect = 0.020 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 229 FISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 287 +G ++D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 288 DVIVLGGGM 296 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 17 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 73 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 74 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 133 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 134 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 193 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 194 RDEAKGKLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 241 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 242 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFFG 298 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 299 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 352 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 2e-04 Identities = 40/264 (15%), Positives = 81/264 (30%), Gaps = 11/264 (4%) Query: 162 LNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSL 221 A P E E + E + Q S V + + A + + A Q+ Sbjct: 1029 APATPSETTETVAENSK-----QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 222 TASLQVLTDEEKQLITAQQQEQQSLNWLTRLD-ELQQEGSRRQQALQQALAEEEKAQPQL 280 + +E Q ++ +++ E QE + + + E QPQ Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 281 AALSLAQPARNLRPHWE---RIAEYSTALAHTRQQIEEVNTRLQSTMALRASIRHHAAKQ 337 P N++ A+ T +E+ T + + + + Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 338 SAELQQQQQSLNAWLQEHDRLRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLN 397 A Q S ++ ++ R + + ++DR + T+ L+ Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA-TTSSNDRSTVALCDLTSTNTNAVLS 1262 Query: 398 ALAAITLTLTADEVASALAQHAEQ 421 A + + V A++QH Q Sbjct: 1263 DARAKAQFVALN-VGKAVSQHISQ 1285 Score = 33.9 bits (77), Expect = 0.005 Identities = 27/139 (19%), Positives = 54/139 (38%), Gaps = 13/139 (9%) Query: 738 QQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQ 797 Q DV + S + A+ D A A E T T E KQ + + Q Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPP-------APATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 798 TLVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDAD 857 TA+ ++ + V E+AQ+ + +E T++ + ++++ Sbjct: 1057 DATETTAQNREVAKEAKS-----NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEK 1111 Query: 858 NRQQQQTLMQQIAQMTQQV 876 + + + Q++ ++T QV Sbjct: 1112 AKVETEK-TQEVPKVTSQV 1129
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 4e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 28.9 bits (64), Expect = 0.006 Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 34 NMFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 70 N KK+LF ++ GCA+ T+ PT P++ Sbjct: 4 NKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 12/144 (8%) Query: 195 KQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQK 254 ++ + L A QV R +++ ++ S+ +Q++A + Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK---KQLEAEHQ 333 Query: 255 ELGEMDDAPD-ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDW 312 +L E + + ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D Sbjct: 334 KLEEQNKISEASRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Query: 313 MVQVPWNARSKVKKDLRQAQEILD 336 + A+ +V+K L +A L Sbjct: 391 SRE----AKKQVEKALEEANSKLA 410
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 27.1 bits (60), Expect = 0.021 Identities = 24/138 (17%), Positives = 41/138 (29%), Gaps = 20/138 (14%) Query: 1 MQTQIKVRGYHLDVYQHVNNARYL-------EFLEEARWHGLENSDSFHWMTAH------ 47 +Q I + Y N Y E++ + N FH + Sbjct: 361 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR 420 Query: 48 ------NIAFVVVN-ININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVA 100 + FV N IN + + + + Q+ L+P+ + Sbjct: 421 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH 480 Query: 101 DALITFVCIDLKTQKALA 118 LI FV +L A+A Sbjct: 481 SQLIPFVHHELTKGIAVA 498
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 10/64 (15%) Query: 197 LTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGN----------AMPQLRAELPH 246 TVL Q L + D +A + + ++ + +P+++ P Sbjct: 16 RTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPD 75 Query: 247 LPVI 250 LPV+ Sbjct: 76 LPVL 79
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.4 bits (71), Expect = 0.002 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 40 TKEHLLPHFL-EHLGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 92 T EHL F+ HL + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 93 AGESKI 98 ++KI Sbjct: 114 ENQNKI 119
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 528 bits (1360), Expect = 0.0 Identities = 313/317 (98%), Positives = 316/317 (99%) Query: 1 MRAKLLGIVLTPPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 MRAKLLGIVLT PIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS Sbjct: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 Query: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR Sbjct: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 Query: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI Sbjct: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 Query: 181 GSFPNGERAIGYKQRFKIPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYDPGKRIT 240 GSFPNGERAIGYKQRFK+PYIGLTGSYRYEDFELGGTFKYSGWVE+SDNDEHYDPGKRIT Sbjct: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 Query: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNDNTSDYSKNGA 300 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHN+NTSDYSKNGA Sbjct: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA 300 Query: 301 GIENYNFITTAGLKYTF 317 GIENYNFITTAGLKYTF Sbjct: 301 GIENYNFITTAGLKYTF 317
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 29/184 (15%), Positives = 67/184 (36%), Gaps = 34/184 (18%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDR-GVELRFV 363 + M +S+++ + + N + + LADE+ V + + LA + L+F Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQ-LASIQFEDRLQFE 243 Query: 364 GDECQVAGDPLMLRRALSNLLSNALRY----TPTGETIVVRCQTVDHLVQVTVENPGTPI 419 D + + L+ N +++ P G I+++ + V + VEN G+ Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 420 APEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSDVRGTRFVI 476 E +G GL V+ ++ + + ++ ++ Sbjct: 304 LKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 477 ILPA 480 ++P Sbjct: 346 LIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.3 bits (89), Expect = 5e-05 Identities = 25/189 (13%), Positives = 60/189 (31%), Gaps = 13/189 (6%) Query: 254 QAQTVNSDSLQSVKLPA-GLPSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + + L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SLFATRQTL 436 L Sbjct: 260 KYVEAVNEL 268
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 693 bits (1789), Expect = 0.0 Identities = 213/1059 (20%), Positives = 438/1059 (41%), Gaps = 54/1059 (5%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRRGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ + +G V L+DVA+V++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVV 352 +G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEG 472 N + + E D + + ++ AL ++++ FIP+ G G Sbjct: 415 NVERVMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 473 RLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRF----------LI 522 ++ + T AMA + L+A+++ P L ++ + E F + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKP-VSAEHHENKGGFFGWFNTTFDHSV 523 Query: 523 RVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISA 582 Y + K+L LL+ AL V ++ ++ FLP+ ++G L M G + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 583 AEAASMLQKTDKLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQW-RPG 639 +L + + V VF G + + + LKP ++ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDE 640 Query: 640 MTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DTMAE 698 + + +I + + + +++ + I +G + + Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 699 QIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGE 758 + A+ + S LE +E+++EKA G++++D+ +++A+GG V + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 759 TVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENA 818 ++ + ++ +R P+ + +L + + + + + G L+ N Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 819 RPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPM 878 P+ I +A L + +A K L G ++G + ++ +V + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 879 TLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGGAA 938 + +++F+ L + + ++ VP +VG + V G + G +A Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 939 EFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPI 998 + ++++ + + +E E + + EA +R+RP MT I G+LP+ Sbjct: 939 KNAILIVEFAKDLMEKE----------GKGVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 999 LWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037 GAGS + + ++GGM++A LL++F +P + + Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 23/269 (8%) Query: 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 187 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 188 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 244 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 245 IIITGEQLSSYEYGLLQVPIFGALIAGNL----LLARLTSRRTVRSLIIMGGWPIMIGLL 300 +I GE ++ + + + I +L + + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 301 VAAAATVISSHAYLWMTAGLSIYAFGIGL 329 + A AT ++ + + + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 218 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 331 DR + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 332 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.6 bits (123), Expect = 1e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 2 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 62 RFTEIMSRQYQAFFSDVSDAP 82 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.006 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSTFSFGMGNAAGLLFAGIML-GFMRANHPTFG-YIPQ--GALSMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGINNGLGAIGGQM--LIAGLIVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.043 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.017 Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 46 LTLLGPSGCGKTTVLRLIAGLE-TVDSGRIMLDNED 80 + L G G GK+T++ + GL+ D+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.048 Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 20/69 (28%) Query: 389 NACKYCLE------FVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQ 442 N K+ + + + + + + + VE+ G + +E Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------------ST 311 Query: 443 GVGLAVARE 451 G GL RE Sbjct: 312 GTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 5e-22 Identities = 31/124 (25%), Positives = 62/124 (50%) Query: 2 RVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLS 61 +LV +D+A +R L + AG+ V +A ++ D+ + D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSG 121 L+ R + LP+LV++A+ ++ ++ GA DY+ KPF + E++ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 LASQ 125 S+ Sbjct: 125 RPSK 128
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.5 bits (63), Expect = 0.032 Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 23/157 (14%) Query: 82 QELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQ 141 Q +QT T V + + P V + Q + + D ++A T Sbjct: 391 QPAEQTTTTTTHTVVQQQTGGIPQHKVALMPQERRRFSDRRDSQGSVASTH--------- 441 Query: 142 FVSPGQMGNIVDKFKEGGNEKVILCDRGA-NFGYDNLVVDMLGFSIMKKVSGNSPVIFDV 200 +V+ + E G + L YD + D G+S+++ SG+ P V Sbjct: 442 --WSDSSSEVVNPYAEVGGARNSLSAHQPEEHIYDEVAADP-GYSVIQNFSGSGP----V 494 Query: 201 THALQCRDPFGAASGGRRAQVAELA-RAGMAVGLAGL 236 T L G G ++ A LA G+ +G+ GL Sbjct: 495 TGRL-----IGTPGQGIQSTYALLANSGGLRLGMGGL 526
>INTIMIN#Intimin signature. Length = 939 Score = 256 bits (654), Expect = 5e-79 Identities = 120/378 (31%), Positives = 193/378 (51%), Gaps = 21/378 (5%) Query: 32 GEQAKAFALGKVRDALSQQVNQHVDSWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 91 G+ AK ALG + S Q+ WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGNQASSQLQA----WLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 92 DRYLTWSQLGLTQQDDGLVSNVGVGQRWARGSWLVGYNTFYDNLLDENLQRAGFGAEAWG 151 ++ L + Q+G D +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 152 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDR 209 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 210 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 269 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 270 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 329 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 330 RSRYGIRQLIWQGDTQILS-----LTPGAQANSEEGWTLIMPDWQNGEGASNHWRLSVVV 384 +S+YG+ +++W D+ + S G+Q S + + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 385 EDNQGQRVSSNEITLTLV 402 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 52.9 bits (127), Expect = 2e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWVQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.011 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 29.8 bits (67), Expect = 0.043 Identities = 21/105 (20%), Positives = 36/105 (34%), Gaps = 2/105 (1%) Query: 526 PIDVELTESCLIENDELALSVIQQFSRLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQV 585 P+ V S I L S + FS + + ++ Q+ D + Sbjct: 425 PLVVVFVASNFINAHLLTDSFPRYFS--DKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQ 482 Query: 586 FVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKEDAFLTK 630 + +H + V I L++Q + V+ K A LTK Sbjct: 483 LIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTK 527
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.4 bits (120), Expect = 1e-09 Identities = 51/260 (19%), Positives = 98/260 (37%), Gaps = 22/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK +TG A I +A+ + +GA + A Y +KL+ V A+ Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDI 119 DV + A+ID + A + + D V+ G L + A F + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN--- 116 Query: 120 SSYSFVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 S+ F A + M++ +++T+ A + +KA+ + + + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 PEGVRVNAISAGPIRTLAASGI--------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +R N +S G T + + + L + P+++ D+ ++ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 231 FLCSDLSAGISGEVVHVDGG 250 FL S + I+ + VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 7e-12 Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 8 MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLSVGQIYRYFANKDAIIE 67 M K + ++ + I++ A R F + G + S+ +IA A ++ G IY +F +K + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 68 EMVRR 72 E+ Sbjct: 61 EIWEL 65
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.9 bits (114), Expect = 4e-08 Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Query: 52 PVSVVSELTGR-TSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNE 110 V +V+ G+ T + S E++P I+++ + KEG+ V+ G L ++ A +A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 111 ARAALQQAQA 120 +++L QA+ Sbjct: 139 TQSSLLQARL 148 Score = 30.6 bits (69), Expect = 0.010 Identities = 15/116 (12%), Positives = 32/116 (27%), Gaps = 9/116 (7%) Query: 94 QPLYQIDAASYQAAWN--EARAALQQAQALVKADCQKAQRYTRLVKENGVSQQDADDAQS 151 L A + A + K+ ++ + KE Q ++ Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE--YQLVTQLFKN 298 Query: 152 TCAQDKASVEAKKAALET----ARINLDWTTVTAPISGRI-GISSVTPGALVTASQ 202 L + + AP+S ++ + T G +VT ++ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1161 bits (3004), Expect = 0.0 Identities = 584/1033 (56%), Positives = 760/1033 (73%), Gaps = 6/1033 (0%) Query: 3 SRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKVSATYTGASAETLENSV 62 + FF+RRP+FAWV+AI++M+AG LAI LPVAQYP +APP + VSA Y GA A+T++++V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 63 TQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQVQVQNKIQQAESRLPSE 122 TQVIEQ + G+DNL+Y SSTS S GSV+I +TF+ GTDPD AQVQVQNK+Q A LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 VQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFGAE 182 VQQ G++VEKS S++L++A + DI+D++ SNV+D L+R+ GVG +Q+FGA+ Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ 181 Query: 183 YAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSRLQ 242 YAMRIWLD L Y L P DV + ++ QN Q+ AG++G P+ QQL A++ AQ+R + Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 243 TVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALN 302 ++F + ++ SDG+VVR+KDVARVE+G E+Y I ++NG P+AG+ + L+ GANAL+ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 303 TATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQN 362 TA +K K+AE Q PQG + YP D+T F+++S+ +V++TLFEAI+LV VMYLFLQN Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 363 LRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMR 422 +RATLIP +AVPVVLLGTF +LA FGYSINTLT+F MVLAIGLLVDDAIVVVENVER+M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 423 DEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAMLLS 482 ++ LP +EATEKSM +I GALV IA+VLSAVF+PMAFFGGSTG IYRQFSITI+SAM LS Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 483 VVVALTLTPALCGSVL----QHVPPHKKGFFGAFNRFYRRTEDKYQRGVIYVLRRAARTM 538 V+VAL LTPALC ++L +K GFFG FN + + + Y V +L R + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 539 GLYVVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINE 598 +Y ++ GM ++ +LP SFLP EDQG + LPAGAT RT +V Q+ D++L NE Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 599 KANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDAT 658 KAN + +FTV+GFSFSG QN GMAFVSLK W +R G EN+A+A+ RA ELG IRD Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 659 VFAMTPPAVDGLGQSNGFTFELLANGGADRETLLQMRNQLIEKANQSP-ELHSVRANDLP 717 V PA+ LG + GF FEL+ G + L Q RNQL+ A Q P L SVR N L Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 718 QMPQLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSA 777 Q ++++D KA +LG+SL+D+ T+S+A GGTYVNDFIDRGRVKK+Y+Q D++FR Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 778 PSDLGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMT 837 P D+ K +VR ++ M PFSAF T+ W+YG RL RYNG + EIQGE A G SSGDAM Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 838 KMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVI 897 ME LA+ LPAG + W+G+S QE+L+ QA +L A+S +VVFLCLAALYESWS+P SV+ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 898 LVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFA-EAAVAEGYSLSR 956 LV+PLG++G LAA + + NDVYF V LLTTIGLS+KNAILIVEFA + EG + Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 957 AALRAAQTRLRPIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFV 1016 A L A + RLRPI+MTSLAFI GV+PLAI+ GAG+ ++ A+G G++GG ++ATLLAIFFV Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 1017 PLFFVLVKRLFAG 1029 P+FFV+++R F G Sbjct: 1022 PVFFVVIRRCFKG 1034 Score = 75.3 bits (185), Expect = 1e-15 Identities = 53/330 (16%), Positives = 117/330 (35%), Gaps = 19/330 (5%) Query: 721 QLQVDIDSNKAVSLGLSLNDVTDTLSSA----WGGTYVNDFIDRGRVKKVYIQGDSEFRS 776 +++ +D++ L+ DV + L G G+ I + F++ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 777 APSDLGKWFVRGSDN-AMTPFSAFATTRWLYGPER--LVRYNGSAA-----YEIQGENAT 828 P + GK +R + + ++ A L G + R NG A G NA Sbjct: 243 -PEEFGKVTLRVNSDGSVVRLKDVARVE-LGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 829 GFSSGDAMTKMEELANSLPAG--TTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAAL 886 + K+ EL P G + + + +L+ +LV + + Sbjct: 301 DTAKA-IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV-MYLF 358 Query: 887 YESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEA 946 ++ + +P+ LLG + + ++ IGL +AI++VE E Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 947 AVAEGYSLSRAALRAAQTRLR-PIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGT 1005 + E + A + ++++ ++ ++ A +P+A G+ I+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 1006 LTATLLAIFFVPLFFVLVKRLFAGKPRRQE 1035 + L+A+ P + + + + + Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.026 Identities = 24/166 (14%), Positives = 49/166 (29%), Gaps = 11/166 (6%) Query: 70 DVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSLANGTVTTAEADGTVSSYTLDL 129 A AD ++ Q +RS L + + + + Sbjct: 128 TALGAEADTLKTQSSLLQARL----EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 130 FGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAKETMASAENS 189 R SL + TW ++ + AE T + + + ++ Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTV-------LARINRYENLSRVEKSR 236 Query: 190 LKIIQRQQQVGTAAATDVSEAMSVYQQARASVASYQTQVMQDKNAL 235 L A V E + Y +A + Y++Q+ Q ++ + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 67.9 bits (166), Expect = 1e-14 Identities = 68/312 (21%), Positives = 114/312 (36%), Gaps = 18/312 (5%) Query: 5 SLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTITQLTLTASLIGLGVGQLLFGP 64 L L L +G L +P LP + L + +T L + Q P Sbjct: 6 PLIVILSTVALDAVG---IGLIMPVLPGLLRDLVHSNDVTA-HYGILLALYALMQFACAP 61 Query: 65 ----LSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWRFIQGIAGAGGSVLSRSIA 120 LSD+ GR+ L++SL V + AT ++ L + R + GI GA G+V IA Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 121 RDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDWRTLFWVMAEISTVLLLGCLL 180 D G + F + G V PVLGG + F F+ A ++ + L Sbjct: 122 -DITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 181 FINETLPENKRGSSL----LLTGRSVVQNRRFMRFCLIQSFMLAGLFAYIGSSSFVL--Q 234 + E+ +R L + + + F + L + ++ +V+ + Sbjct: 180 LLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF-IMQLVGQVPAALWVIFGE 238 Query: 235 KEFGFSPMQFSLVFGLNGI-GLIIASWIFSRLARRINAMTLLRGGLIAAILCALLTVLCA 293 F + + GI + + I +A R+ L G+IA +L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 294 WVQLPIPALVAL 305 + P +V L Sbjct: 299 RGWMAFPIMVLL 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGKSLIAKAI 53 + GESG+GK L+A+A+ Sbjct: 165 ITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 343 bits (882), Expect = e-118 Identities = 126/341 (36%), Positives = 183/341 (53%), Gaps = 23/341 (6%) Query: 11 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 70 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 71 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 130 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 131 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 190 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 191 IMLMAEHFAIQMCREIKLPLFPGFTEHARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 250 I + HF Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 251 PLDDIIID---PFKRRPSEEAIAVSENTSLPTLPLD------------------LREFQM 289 + I + P E+A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 290 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 330 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 507 bits (1308), Expect = 0.0 Identities = 288/317 (90%), Positives = 301/317 (94%), Gaps = 1/317 (0%) Query: 1 MRAKLLGIVLTTPIAICSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGQKVS 60 MRAKLLGIVLTTPIAI SFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGG+KVS Sbjct: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 Query: 61 QLDWKFNNAAIIKGAINWDLMPQVSVGAAGWTTLGQKGGNMIDRDWQDPDKPGIWTDESR 120 QLDWKFNNAAIIKGAINWDLMPQ+S+GAAGWTTLG +GGNM+D+DW D PG WTDESR Sbjct: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 Query: 121 HPDTRLNFANEFDLNIKGWLLNESNYRLGLMAGYQESRYSFTARGGSYIYSDE-GFRDDI 179 HPDT+LN+ANEFDLNIKGWLLNE NYRLGLMAGYQESRYSFTARGGSYIYS E GFRDDI Sbjct: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 Query: 180 GSIPNGERVIGYKQRFKMPYIGLTGSYRYEDFEFGGTFKYSGWVEASDNDEHYARVKRIT 239 GS PNGER IGYKQRFKMPYIGLTGSYRYEDFE GGTFKYSGWVE+SDNDEHY KRIT Sbjct: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 Query: 240 YRSKVKDQNYYSIAVNAGYYVTPNAKVYVEGAWNRVTNKKGDTSLYDHNDNTSEYSKNGA 299 YRSKVKDQNYYS+AVNAGYYVTPNAKVYVEGAWNRVTNKKG+TSLYDHN+NTS+YSKNGA Sbjct: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA 300 Query: 300 GIENYNFITTAGLKYTF 316 GIENYNFITTAGLKYTF Sbjct: 301 GIENYNFITTAGLKYTF 317
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 581 bits (1500), Expect = 0.0 Identities = 312/388 (80%), Positives = 337/388 (86%), Gaps = 16/388 (4%) Query: 1 MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYFSDNSAKDGDQSYARLG 60 MK KVLAL+IPALLAAGAAHAAE+YNKDGNKLDLYGKVDGLHYFSD+S+KDGDQ+Y R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQLTGYGQWEYNIQANNTESSTNQSWTRLAFAGLKFADYGSFDYGRNYGVMY 120 FKGETQINDQLTGYGQWEYN+QAN TE SWTRLAFAGLKF DYGSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 121 DIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFFGLVNGLNFAVQYQGNNEGAS 180 D+EGWTDMLPEFGGDSYT ADN+MTGRANGVATYRNTDFFGLV+GLNFA+QYQG NE S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 181 N-----GQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAYTSSDRTNDQVNH--TAA 233 G NNG D+R++NGDG+G+STTYD+GMGFSAGAAYT+SDRTN+QVN T A Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 234 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDS----DYAVANKTQNFEVTAQYQF 289 GGDKADAWTAGLKYDANNIYLATMYSETRNMTP+G + D VANKTQNFEVTAQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 290 DFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATYYFNKNMSTYVDYKIN 349 DFGLRPAVSFLMSKG+DL N DDKDLVKYADVGATYYFNKN STYVDYKIN Sbjct: 301 DFGLRPAVSFLMSKGKDL-----TYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 350 LLDEDDSFYAANGISTDDIVALGLVYQF 377 LLD+DD FY GISTDDIVALG+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 424 bits (1093), Expect = e-151 Identities = 95/346 (27%), Positives = 178/346 (51%), Gaps = 2/346 (0%) Query: 5 SDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSVIWFGGVSLARRLSGMLSAGL 64 S +KTE PTP ++ AR++GQ+ +S+E+ S +++ +++ S ++ + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML--I 59 Query: 65 HFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLVAIISPVMLGGLVFSGKSLQPKF 124 + S + + + ++ E PL++ L+AI S V+ G + SG++++P Sbjct: 60 PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 125 SKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTGFFLWHHWPQMMRLMAESPITAMGN 184 K+NP+ G KR+FS ++ E LK+ILK +L+ + + + +++L Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 185 AMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKQSEGDPHVKGRIR 244 ++ ++ +G + + D F+ + ++K+L+MS+ +I+ E+K+ EG P +K + R Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 245 QMQRAAARRRMMADVPKADVIVNNPTHYSVALQYDENKMSAPKVVAKGAGLVALRIREIG 304 Q + R M +V ++ V+V NPTH ++ + Y + P V K +R+I Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 305 AENNVPTLEAPPLARALYRHAEIGQQIPGQLYAAVAEVLAWVWQLK 350 E VP L+ PLARALY A + IP + A AEVL W+ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 9e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGLDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.4 bits (162), Expect = 3e-14 Identities = 35/188 (18%), Positives = 73/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSVPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPL-----------------VGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 2e-05 Identities = 22/151 (14%), Positives = 48/151 (31%), Gaps = 52/151 (34%) Query: 374 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 431 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 432 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 491 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 492 KRNIQEMGG---HVEIQSMQGTGTTIRILLP 519 + +Q + G +++ QG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.009 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 32.7 bits (74), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 201 bits (514), Expect = 1e-66 Identities = 257/261 (98%), Positives = 261/261 (100%) Query: 1 MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 M+QVTS+QWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEMFNLLADIISELPLI 261 EHLFSE+FNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.0 bits (117), Expect = 2e-08 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Query: 132 AMMLH-IRQQAQAQLPEAITQAVIGRPINFQGLGSDEANTQAQGILERAAKRAGFKDVVF 190 M+ H I+Q + ++ P+ + + + I E +A+ AG ++V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV-------ERRAIRE-SAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 35.1 bits (81), Expect = 5e-04 Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 23/137 (16%) Query: 332 RLSYRLV---RSAEESKIALSSV--AETRASLPFISDELAT------LISQQGLESALNQ 380 R +Y + +AE K + S + + LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 381 PLARILEQVQLALDNAQEKPDV--------IYLTGGSARSPLIKKALAEQLPGIPIAGGD 432 PL I+ V +AL+ Q P++ + LTGG A + + L E+ GIP+ + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 433 D-FGSVTAGLARWAEVV 448 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.6 bits (103), Expect = 4e-07 Identities = 42/195 (21%), Positives = 77/195 (39%), Gaps = 18/195 (9%) Query: 4 MPKFRVSLFSLALMLAVPFAPQAVAKTVAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 62 M R+ + SL + +P A A + + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 63 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 119 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 120 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 172 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 173 HNVSTARDLTKLLIA 187 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.6 bits (64), Expect = 0.017 Identities = 5/33 (15%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 164 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKR 194 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (281), Expect = 4e-32 Identities = 70/253 (27%), Positives = 116/253 (45%), Gaps = 12/253 (4%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTARKVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I + E + + + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 63 NLPEGAQALEKLIQRLWRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIA 122 + + ++ + + ID+LVN AG + ++ +EW F+V+ G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVA 182 ++ M+ + + G I+ + S P +AY ++K A TK + LEL + I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPMN-----GMDGGD--VKPDAEP---SIPLRRFGTTHEIASLVAWLCSEGANYT 232 PG+ T M +G + +K E IPL++ +IA V +L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.3 bits (66), Expect = 0.018 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 122 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 179 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 180 HIDWQAIGE-IRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVK 238 ++ I E +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 239 YNEPRMP 245 E +P Sbjct: 308 MEETGIP 314
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 60.3 bits (146), Expect = 4e-12 Identities = 77/385 (20%), Positives = 146/385 (37%), Gaps = 55/385 (14%) Query: 13 ALPVISAQFGVPAGSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVA 72 +LP I+ F P ST + ++L F++G +YG ++D G K ++L G ++ +V Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI 95 Query: 73 CALAQTIDQLIVM-RFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMA 131 + + L++M RF G AAA ++ ++ PKE + + + + + Sbjct: 96 GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVG 155 Query: 132 PIVGGWVLVWLSWHYIFWILAVAAILASAMIFFLIKETLPPERR-QPFHIRTTIGNFAA- 189 P +GG + ++ W Y+ I + I + FL+K R F I+ I Sbjct: 156 PAIGGMIAHYIHWSYLLLIPMITII----TVPFLMKLLKKEVRIKGHFDIKGIILMSVGI 211 Query: 190 ----------------------------------------LFRHKRVLSYMLASGFSFAG 209 L ++ + +L G F Sbjct: 212 VFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGT 271 Query: 210 MFSFLSAGPFVYIEINHVAPENFGYYFAL-NILFLFVMTIFNSRFVRRIGALNMFRSGLW 268 + F+S P++ +++ ++ G + + + V R G L + G Sbjct: 272 VAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIG-- 329 Query: 269 IQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDEF-PHMAGTASSLA 327 + F+ +++ S LL W + + + +G +S + ++ AG SL Sbjct: 330 VTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLL 389 Query: 328 GTFRF---GIG-AIVGALLSLATFN 348 F G G AIVG LLS+ + Sbjct: 390 NFTSFLSEGTGIAIVGGLLSIPLLD 414
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.027 Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 503 LHVSTPASEYSQGQ-DLF---NPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNL 558 L V+ E + + LF QR H V+ +T+ + K L N NG+Y YN Sbjct: 926 LQVADKTGEPNHNELTLFDASKAQRDHLNVSLV-GNTVDLGAWKYKLR-NVNGRYDLYNP 983 Query: 559 RGERVKDEKP 568 E+ Sbjct: 984 EVEKRNQTVD 993
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 48.9 bits (116), Expect = 2e-09 Identities = 35/164 (21%), Positives = 51/164 (31%), Gaps = 37/164 (22%) Query: 19 GAANDPTIKGGRGDAAFTLGNAGSVVDISTYEYTLLDNGNHSWSLAENRV---------- 68 A FTL N VDI TY Y L NGN WSL + Sbjct: 522 ANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQP 581 Query: 69 -----------------------QMPPSTTDVLN---MAAAQPLVFDVELDTVRGRLGSV 102 ++ + +N + A L + E + + RLG + Sbjct: 582 GPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWY-AESNALSKRLGEL 640 Query: 103 KGVNYDTAMWSSAINSRNNVNTDAGAGFEQTLTGLTLGIDSRFS 146 + W R ++ AG F+Q + G LG D + Sbjct: 641 RLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVA 684
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 534 bits (1377), Expect = 0.0 Identities = 254/383 (66%), Positives = 293/383 (76%), Gaps = 20/383 (5%) Query: 1 MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLG 60 MK KVL+L++PALL AGAA+AAE+YNKDGNKLDLYGKVDGLHYFSDD S DGDQTYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVTDQLTGYGQWEYQIQGNSAENE-NNSWTRVAFAGLKFQDVGSFDYGRNYGVVY 119 FKGETQ+ DQLTGYGQWEY +Q N+ E E NSWTR+AFAGLKF D GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTYG-SDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGSVS 178 DV WTD+LPEFGGD+Y +DN+M R NG ATYRNTDFFGLVDGLNFA+QYQGKN S S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 ------GEGMTNNGRGALRQNGDGVGGSITYDY-EGFGIGGAISSSKRTDDQN-SPLYIG 230 G NNG NGDG G S TYD GF G A ++S RT++Q + I Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 231 NGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL------GWANKAQNFEAVAQYQF 284 GD+A+ +T GLKYDANNIYLA Y++T N T G G ANK QNFE AQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 285 DFGLRPSLAYLQSKGKNLGR---GYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLD-D 340 DFGLRP++++L SKGK+L DD+D++KY DVGATYYFNKN STYVDYKINLLD D Sbjct: 301 DFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDD 360 Query: 341 NQFTRDAGINTDNIVALGLVYQF 363 + F +DAGI+TD+IVALG+VYQF Sbjct: 361 DPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 9e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 1 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 60 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 114 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQKGKKFTPESVSRLLE 139 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-17 Identities = 29/106 (27%), Positives = 48/106 (45%) Query: 811 ILVVDDHPINRSLLADQLGSLGYQCKTANDGVDALNVLNKNHIDIVLSDVNMPNMDGYRL 870 ILV DD R++L L GY + ++ + D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 871 TQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVI 916 RI++ LPV+ ++A + E G L KP L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 562 bits (1449), Expect = 0.0 Identities = 181/484 (37%), Positives = 269/484 (55%), Gaps = 35/484 (7%) Query: 1 MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPE 60 MT IL+ DD+ +R +L+ A + G++ +N T A D+V+ D+ MP+ Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 MDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRAL 120 + L ++ PV++M+A TA++A GA+DY+ KPFDL EL I+ RAL Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QLQSMKKEIRHLHQALSTSWQWGH-ILTNSPAMMDICKDTAKIALSQASVLISGESGTGK 179 + L Q G ++ S AM +I + A++ + +++I+GESGTGK Sbjct: 120 AEP------KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 180 ELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEG 239 EL+ARA+H +R GPF+ +N AA+P L+ESELFGHEKGAFTGAQT G FE+A G Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 240 TLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFR 299 TL LDEIG+MP+ Q +LLR+LQ+ E+ +GG I+ D+RI+AATN+DL+ + +G FR Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 300 EDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWP 359 EDL+YRLNV+ L LPPLRDR EDI L HF+Q+ E + D A+ L+ A WP Sbjct: 294 EDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWP 352 Query: 360 GNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPV---------CNAGEAKTAPVGERN- 409 GN+REL N++ R + +I E + ++R + +G + E N Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 410 ----------------LKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQE 453 + +E +I+ L GN+ + A +LG++R L K++E Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472 Query: 454 YGID 457 G+ Sbjct: 473 LGVS 476
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.1 bits (104), Expect = 7e-07 Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASMLMALMALALWRGLPQMKSETHLNY 196 + G++A+ W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.018 Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 23 PYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRR 111 SS ++ D L + GW RE+ RR Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRR 842
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 131 bits (332), Expect = 1e-35 Identities = 97/405 (23%), Positives = 169/405 (41%), Gaps = 23/405 (5%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 135 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 195 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 196 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTD 255 + D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 195 I-KGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 DNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 315 +P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGF- 373 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 374 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 416 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 292 bits (750), Expect = e-105 Identities = 131/170 (77%), Positives = 148/170 (87%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA++ILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>cloacin#Cloacin signature. Length = 551 Score = 33.9 bits (77), Expect = 8e-04 Identities = 16/30 (53%), Positives = 18/30 (60%) Query: 266 GSSSSSSGGGSSGGGFSGGGGSSGGGGASG 295 GS S GG SG G GG G+SGGG +G Sbjct: 49 GSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78 Score = 31.2 bits (70), Expect = 0.005 Identities = 12/23 (52%), Positives = 14/23 (60%) Query: 272 SGGGSSGGGFSGGGGSSGGGGAS 294 SG G+ GG + GGGS GG S Sbjct: 60 SGHGNGGGNGNSGGGSGTGGNLS 82 Score = 29.7 bits (66), Expect = 0.016 Identities = 11/32 (34%), Positives = 14/32 (43%) Query: 263 SRKGSSSSSSGGGSSGGGFSGGGGSSGGGGAS 294 S S G G G SGGG +GG ++ Sbjct: 52 SGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 29.3 bits (65), Expect = 0.022 Identities = 13/30 (43%), Positives = 16/30 (53%) Query: 266 GSSSSSSGGGSSGGGFSGGGGSSGGGGASG 295 S ++ GGGS G GGG G GG +G Sbjct: 40 SSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Score = 28.5 bits (63), Expect = 0.038 Identities = 13/38 (34%), Positives = 16/38 (42%) Query: 258 SKERASRKGSSSSSSGGGSSGGGFSGGGGSSGGGGASG 295 S E G S S G G +GGG + GGG+ Sbjct: 40 SSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGT 77 Score = 28.1 bits (62), Expect = 0.042 Identities = 12/30 (40%), Positives = 13/30 (43%) Query: 263 SRKGSSSSSSGGGSSGGGFSGGGGSSGGGG 292 S G G +GGG GG SG GG Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.038 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%) Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265 P L N + A+ +E K YE+GK I+L + + ++ + + Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206 Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321 S++F LE K I I++ L E F+Y ++L D+F Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266 Query: 322 TNTKILKEGIEK 333 K+ K G EK Sbjct: 267 YMNKLEKGGFEK 278
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.1 bits (65), Expect = 0.002 Identities = 27/114 (23%), Positives = 43/114 (37%), Gaps = 29/114 (25%) Query: 8 QQGFSLPEVMLAMVLMVMIVTA----------------LSGFQRTLMNSLASRNQYQQLW 51 Q+GF+L E+ML ++LM + L+ F+ L Q Q + Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 52 -----RHGWQ--QTQLRAISPPA----NWQVNRMQTSQAGCVSISVTLVSPGGR 94 WQ + R + PA W R +AG V+ S ++ GG+ Sbjct: 63 GVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSI--AGGK 114
>PilS_PF08805#PilS N terminal Length = 185 Score = 28.7 bits (64), Expect = 0.016 Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 3/51 (5%) Query: 72 ALSARRNRRMPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTNT 122 +LSARR + +++G +L+EVL+ + + VL A + +Q ++ Sbjct: 15 SLSARRKKE---QDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSN 62
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.003 Identities = 9/24 (37%), Positives = 18/24 (75%) Query: 1 MKTQRGYTLIETLVAMLILVMLSA 24 QRG+TL+E +V ++I+ +L++ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLAS 27
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 611 bits (1577), Expect = 0.0 Identities = 189/571 (33%), Positives = 314/571 (54%), Gaps = 7/571 (1%) Query: 168 QTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEEAANEFRRYS 227 +I + A+ GVAIA+ + + + + S D + E E+LT ALE++ E R Sbjct: 2 HHKITGIAASSGVAIAKAFIHLEPNV--DIEKTSITDVSTEIEKLTAALEKSKEELRAIK 59 Query: 228 KRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSV-AEWAVKTVIEKFAEQFAAL 286 + A + A IF + +L D L + +++ + AE+A+K V + F F ++ Sbjct: 60 DQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESM 119 Query: 287 SDNYLKERAGDLRALGQRLLFHLDDANQGPNAW-PERFILVADELSATTLAELPQDRLVG 345 + Y+KERA D+R + +R+L HL G A E +++A++L+ + A+L + + G Sbjct: 120 DNEYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKG 179 Query: 346 VVVRDGAANSHAAIMVRALGIPTVMGA-DIQPSVLHRRTLIVDGYRGELLVDPEPVLLQE 404 G SH+AIM R+L IP V+G ++ + H +IVDG G ++V+P ++ Sbjct: 180 FATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKA 239 Query: 405 YQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEKLGSRIDGIGLYRTE 464 Y+ + + + V P+ K G +++ N G + + L + +GIGLYRTE Sbjct: 240 YEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTE 299 Query: 465 IPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQLPYMPISEE-NPCLGWR 523 +M + P+EEEQ Y+ ++Q + KPV +RTLD+G DK+L Y+ + +E NP LG+R Sbjct: 300 FLYMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFR 359 Query: 524 GIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVDEARRLIERAGREVEEMI 583 IR+ L++ +IF Q+RA+LRA + GNL ++ PM+ +L+E+ +A+ +++ ++ Sbjct: 360 AIRLCLEKQDIFRTQLRALLRA-STYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEG 418 Query: 584 GYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQYILAVDRNNTRVANIYDSL 643 +GIM+E+PS AK VDF S+GTNDL QY +A DR N RV+ +Y Sbjct: 419 VDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPY 478 Query: 644 HPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILIGLGYRHLSMNGRSVARVKYLL 703 HPA+LR + M+ + A G + +CGEMAGD + + +L+GLG SM+ S+ + L Sbjct: 479 HPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQL 538 Query: 704 RRIDFAEAENLAQRSLEAQLATEVRHQVAAF 734 ++ E + AQ++L A EV V Sbjct: 539 LKLSKEELKPFAQKALMLDTAEEVEQLVKKT 569
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.7 bits (178), Expect = 3e-16 Identities = 30/184 (16%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 90 GLGSGVIINANKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 137 + SGV++ + +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVGKDT--LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 138 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIISALG 190 D+A+++ + ++++ + +V G P ++ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 191 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 250 MART 253 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 168 bits (428), Expect = 9e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKELYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 2e-10 Identities = 29/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQVLFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG VL + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.4 bits (63), Expect = 0.043 Identities = 12/72 (16%), Positives = 20/72 (27%), Gaps = 3/72 (4%) Query: 296 MMPQVLPSPDAMGPKLPEPATGITQPTPQQPATGNAVTAPAAPTQPAANRSPQRATPPQS 355 P+ +P P P + E +P P+ V P +P +R Sbjct: 78 PEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK---KVEQPKRDVKPVESRPASPFENTAP 134 Query: 356 GAQPPARAPGGQ 367 + A Sbjct: 135 ARPTSSTATAAT 146
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 576 bits (1487), Expect = 0.0 Identities = 347/347 (100%), Positives = 347/347 (100%) Query: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60 Query: 61 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ Sbjct: 61 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120 Query: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG Sbjct: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180 Query: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN Sbjct: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240 Query: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 Query: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.017 Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 150 IVVTGASGGVGSTAVALLHKLGYQVVAV 177 +VTGA+G +G L + G+QVV + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 127 bits (321), Expect = 7e-39 Identities = 77/209 (36%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK EA +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQDHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL + A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 98 ATYQASYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 299 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQASY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191 Score = 29.0 bits (65), Expect = 0.031 Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 65 AEVRPQVSGIVLNRN-FTEGSDVQAGQSLYQIDP 97 + +R VS V TEG V ++L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1405 bits (3639), Expect = 0.0 Identities = 1029/1034 (99%), Positives = 1032/1034 (99%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIQEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI EVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPP+EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKMELGKIRDG 660 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEER+GDENSAEAVIHRAKMELGKIRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRM 780 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK+YVQADAKFRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVIRRCFKG 1034 VPVFFVVIRRCFKG Sbjct: 1021 VPVFFVVIRRCFKG 1034
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 83.9 bits (207), Expect = 4e-21 Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 15/200 (7%) Query: 59 EFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGNEQKRY 118 +F+L + +N AG DA N L+++L G++ +D S +I++ NEQ Sbjct: 64 DFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSR 122 Query: 119 SLNEALESAPGT--FIRKINKTSVVFETHGHYEKVTLH-------PGLP--DIIKQPDSE 167 +NE + PG I I VV + G YE + L+ G+P + +Q Sbjct: 123 GVNEEV---PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQR 179 Query: 168 NQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVS 227 ++DY+ +PI + ++ G RLNP ++F LQ D+A+ +N L L ++ Sbjct: 180 ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAK 239 Query: 228 QALSLLLTQQSAQFTIRRNG 247 +A+ + + T+ R+G Sbjct: 240 KAMERMADVHNFTLTVERDG 259
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 716 bits (1850), Expect = 0.0 Identities = 344/629 (54%), Positives = 466/629 (74%), Gaps = 11/629 (1%) Query: 11 ITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRS 70 +T + AALL A E++ A+F DI++F+ V ++L KT++IDPSV+GTI+VRS Sbjct: 12 LTLLIFAALLF---RPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 71 NDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELV 130 D ++++YYQFFLS+LD+YG++VI ++NG LKVVRS + KT+ +A + PG+GDE+V Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVV 128 Query: 131 TRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 190 TR+VPL NV ARDLAPLLRQ+ D VG+VVHYEPSNVL++TGRA+ I +L+ +++RVD Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 191 IGTEKQQIIHLEYASAEDLAEILNQLISESHGKSQMPALLSAKIVADKRTNSLIISGPEK 250 G + L +ASA D+ +++ +L ++ KS +P + A +VAD+RTN++++SG Sbjct: 189 AGDRSVVTVPLSWASAADVVKLVTEL-NKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 251 ARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNSRKPSSTS 310 +RQRI +++K LD +++ +GNT+V YLKYAKA++LVEVLTG+S ++ EK ++ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAK--PVAA 305 Query: 311 AMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLG 370 N+ I A QTN+L++TA V L VIA+LDIRR QVLVEAII EVQD +GLNLG Sbjct: 306 LDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLG 365 Query: 371 VQWANKNVGAQQFTNTGLPVFNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNGD 430 +QWANKN G QFTN+GLP+ A G Y K+G ++S+ S++NG+AAGF+ G+ Sbjct: 366 IQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLA--SALSSFNGIAAGFYQGN 423 Query: 431 WGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKT 490 W +LLTAL+S+ KNDILATPSIVTLDN A+FNVGQ+VPVL+GSQTTSGDN+FNTVERKT Sbjct: 424 WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKT 483 Query: 491 VGTKLKVTPQVNEGDAVLLEIEQEVSSVD---SSSNSTLGPTFNTRTIQNAVLVKTGETV 547 VG KLKV PQ+NEGD+VLLEIEQEVSSV SS++S LG TFNTRT+ NAVLV +GETV Sbjct: 484 VGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETV 543 Query: 548 VLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSL 607 V+GGLLD + KVPLLGDIP++G LFR TS + +KRNLM+FIRPT+IRD D YR Sbjct: 544 VVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQA 603 Query: 608 SKEKYTRYRQEQQLRIDGKSKALIGSEDL 636 S +YT + Q + ++ + ++DL Sbjct: 604 SSGQYTAFNDAQSKQRGKENNDAMLNQDL 632
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 512 bits (1321), Expect = 0.0 Identities = 195/405 (48%), Positives = 283/405 (69%), Gaps = 8/405 (1%) Query: 2 NYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQK-------SSGVKTRRP 54 Y Y+A+ G+K +G +A+ RQAR LRE GL L + + S+G+ RR Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 -RISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNNRLADVLNQVRSAILEGHPLSD 113 R+S S+L L TRQLATL AA++PLEE+L + +QS L+ ++ VRS ++EGH L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 114 ALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKLIQSLIYPCMLTTV 173 A++ FP F+ LY +V AGE SG L VL +LADY E RQ++RS++ Q++IYPC+LT V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 174 AIVVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTGPTLLATVFIVAVGFW 233 AI VV ILL+ VVPK+ EQF+HMKQ LPLSTR+L+G+SD ++ GP +L + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 234 LWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQSSGVPLLDGMNLSTESLN 293 + L++ R FH LL + LIG + +N+ARY RTLSIL +S VPLL M +S + ++ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 294 NLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVASGEKSGQLGTLMVRAADNQE 353 N R RL+ A + VR+G S+H +LEQTA+FPPMM +M+ASGE+SG+L +++ RAADNQ+ Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 354 TLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQLNSMIN 398 +++ L L +FEP L+++MA +VLFIV+++LQP+LQLN++++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 249 bits (636), Expect = 1e-88 Identities = 144/145 (99%), Positives = 144/145 (99%) Query: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNHRYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 LDNH YPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145 LSAGPDGEMGTEDDITNWGLSKKKK Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 142 bits (358), Expect = 9e-46 Identities = 50/154 (32%), Positives = 76/154 (49%), Gaps = 18/154 (11%) Query: 3 QQRGFTLLEMMLVLALVAITASVVLFTYGREDAASTRARETAARFTAALELAIDRATLSG 62 +QRGFTLLEMML+L L+ ++A +VL + + A +T ARF A L R +G Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFP--ASRDDSAAQTLARFEAQLRFVQQRGLQTG 59 Query: 63 QPVGIHFSDSAWRIMV----PGKTP-------SAWRWVPLQEDAADESKNDWGEELSIQL 111 Q G+ W+ +V G P S +RW+PL+ S + G +L++ Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNLAF 119 Query: 112 ---QPFKPDDSNQPQVVILADGQITPFSLLMANA 142 + + P D P V+I G++TPF L + A Sbjct: 120 AQGEAWTPGD--NPDVLIFPGGEMTPFRLTLGEA 151
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.0 bits (70), Expect = 9e-04 Identities = 18/91 (19%), Positives = 42/91 (46%), Gaps = 4/91 (4%) Query: 14 MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQ--RTAIERMRNETLALWIADNQLQSQD 71 +KQ G TLLE+++ + I +A ++ ++ G + ++ ++ +AL A + + D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK-LD 62 Query: 72 SFDEENTSSSGKELINGEELINGEEWNWRSD 102 + T+ + L+ L N+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTL-PPLAANYNKE 92
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.8 bits (77), Expect = 2e-04 Identities = 12/47 (25%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 4 RQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKEIQQFNQ 50 RQ+GFTLLE+M L + + + + + F + + + + + +F Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRD--DSAAQTLARFEA 46
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 152 bits (386), Expect = 1e-47 Identities = 88/262 (33%), Positives = 119/262 (45%), Gaps = 47/262 (17%) Query: 5 LPLFILVGFIAGYFVNVMAYHL---------------SPLEDKTALTFRQVLVH------ 43 L L + G F+NV+ + L +D+ L+ Sbjct: 16 FSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCCP 75 Query: 44 FWQKKYAWHDTVPLI-------------------------LCVAAAIACALAPFTPIVTG 78 + +PL+ L ++A A+ T Sbjct: 76 HCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGTL 135 Query: 79 ALFLYFCFALTLSVIDFRTQLLPDKLTLPLLWLGLVFNAQSGLIDLHDAVYGAVAGYGVL 138 A L + L+ ID LLPD+LTLPLLW GL+FN G + L DAV GA+AGY VL Sbjct: 136 AALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVL 195 Query: 139 WCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRR 198 W +YW L+ KEG+GYGDFKLLAA GAW GWQ LP++LL++SL G I LL+ Sbjct: 196 WSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNH 255 Query: 199 TITT-IAFGPWLALGSMINLGY 219 + I FGP+LA+ I L + Sbjct: 256 HQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 35.2 bits (81), Expect = 3e-05 Identities = 28/150 (18%), Positives = 59/150 (39%), Gaps = 24/150 (16%) Query: 5 TKVINYLNKLLGNE---LVAINQYFLHARMFKNWGLKRLNDVEYHESIDEM-----KHAD 56 T V N LN L N ++++ +W +K + HE +E+ + D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRF--------HWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 57 RYIERILFLEGLPN--LQDLGKL------NIGEDVEEMLRSDLALELDGAKNLREAIGYA 108 ER+L + G P +++ + EM+++ + + + IG A Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 109 DSVHDYVSRDMMIEILRDEEGHIDWLETEL 138 + D + D+ + ++ + E + L + L Sbjct: 123 EENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKILELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.7 bits (64), Expect = 0.023 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 164 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 222 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 223 SK 224 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 132 bits (334), Expect = 5e-40 Identities = 79/226 (34%), Positives = 124/226 (54%), Gaps = 9/226 (3%) Query: 28 AAKPATTADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 12 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 69 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 70 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 119 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 120 RYDALNRYPMSDVLR 134 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.004 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 50.3 bits (120), Expect = 4e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKV-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.046 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 83.3 bits (206), Expect = 9e-20 Identities = 71/408 (17%), Positives = 138/408 (33%), Gaps = 81/408 (19%) Query: 6 RHLAWWGVGALAVAAVVAWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++ +G L +A +++ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.4 bits (66), Expect = 0.023 Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 24/109 (22%) Query: 215 VITAENGIVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRN 272 ++ E I RE RG GP +L + ++ + + + L T + N Q Sbjct: 58 LLNLEEAITLRE------RGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLK 107 Query: 273 AHPNQSLKNTLAVHL------------PKRLVERLQQLGQIPDVSLKQL 309 A N LK L ++L P R++ QQL + +V L Sbjct: 108 ALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.1 bits (143), Expect = 1e-11 Identities = 41/184 (22%), Positives = 80/184 (43%), Gaps = 1/184 (0%) Query: 7 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 66 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 67 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLMVLIAASAMQGMGTGVGGVMARTLPRD 125 +SD++G + ++L G+ I +++ V S +LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 126 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 185 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 186 PETR 189 E R Sbjct: 191 KEVR 194
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 49/262 (18%), Positives = 105/262 (40%), Gaps = 43/262 (16%) Query: 197 ILFALATVLLA-SVLSFFW-YRRYLRSRQLLQDEMKRKEKLVALGHLAAGV-AHEIRNPL 253 I+F + V S+L F W + + + ++ Q +M + L L A + H + N L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 254 SSIKGLAKYFAERAPAGGEAHQLAQVM---AKEADRLNRVVSELLELVKPTHLALQAVEL 310 ++I+ L +A L+++M + ++ +++ L +V ++L L +++ Sbjct: 180 NNIRALILEDPTKAREM--LTSLSELMRYSLRYSNARQVSLADELTVVD-SYLQLASIQF 236 Query: 311 NTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLL-NLYLNAIQAIGQHG 369 + Q+ + ++Q+ P L Q L+ N + I + Q G Sbjct: 237 EDRLQFENQI---NPAIMDVQV--------------PPMLVQTLVENGIKHGIAQLPQGG 279 Query: 370 VISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGG 429 I + ++ V + V ++G + E TG GL V ++ G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGTGLQNVRERLQMLYG 327 Query: 430 ---TIQVASQEGKGATFTLWLP 448 I+++ ++GK + +P Sbjct: 328 TEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 526 bits (1356), Expect = 0.0 Identities = 184/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKTLNPAIPVLIMTAYSSIETAVEALKTGALDYLIKPLDFDNLQSTLEKALAHTHSV 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVSASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ S +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLVQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.7 bits (72), Expect = 6e-04 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 37 IANFFVAEKVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVA 96 IA+FFV EK+LQ + Q+H S P+ R+ + V G +QVE R + E Sbjct: 81 IADFFVTEKMLQHFIKQVHSNSF---MRPSPRVLVCVPV------GATQVERRAIRESAQ 131 Query: 97 GA 98 GA Sbjct: 132 GA 133
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 1e-04 Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 78 IDPDVRGCGVGRMLVKHALSMAPE-----LTTNVNEQNEQAVGFYKKVGFKVTG 126 + D R GVG L+ A+ A E L + N A FY K F + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/58 (24%), Positives = 23/58 (39%) Query: 294 ETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYK 351 ET+ PD+ L A P L Y + N D +T + + QL+++ Sbjct: 544 ETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNAT 601
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.019 Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 17/87 (19%) Query: 348 SGLEPLNIGEDSLFVNVGERTN---VTGSA----KFKRLIKEEKYSEALDVARQQVENGA 400 +P+ + ++ + +TN VT + +R+I + LD+ R QV A Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQ------LDIRRPQVLVEA 351 Query: 401 QIIDINMDEGMLDAEAAMVRFLNLIAG 427 I ++ D L+ +++ N AG Sbjct: 352 IIAEVQ-DADGLNLG---IQWANKNAG 374
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.017 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.7 bits (103), Expect = 1e-06 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLDWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRS 260 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 261 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 315 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 316 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 353 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 39.0 bits (91), Expect = 3e-05 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 401 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITG-VTMKETANR 444 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 7e-05 Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 34/182 (18%) Query: 181 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 237 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 238 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDGGAV-MAVEDE 292 + + D+ V ML++ LVEN ++ PQG I++K +D G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 293 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWI 351 G + + G GL V R+ L+ + ++ ++ A + Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 352 RL 353 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 42/121 (34%), Positives = 60/121 (49%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVSTARMAEQSLEAGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY S A + + AG LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>PF06580#Sensor histidine kinase Length = 349 Score = 203 bits (518), Expect = 4e-64 Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 14/214 (6%) Query: 203 RKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLAFLEDAQRTETMVHDFSDMMRYL 262 + ++ EA+ AL QINPHF+FN LN I L LED + M+ S++MRY Sbjct: 149 IDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALI-LEDPTKAREMLTSLSELMRYS 207 Query: 263 LRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVENF 322 LR ++ ++L +E+ V++Y+ + ++ DR + I +DV P +++Q LVEN Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENG 267 Query: 323 FNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINN 382 + + +L++ T D V +EV + G +T + G+ N Sbjct: 268 IKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK----------ESTGTGLQN 317 Query: 383 IKNRLKLLFGESYGLEIMSPNKPRMGTTIKLRFP 416 ++ RL++L+G +++ + P Sbjct: 318 VRERLQMLYGTEAQIKLSEKQG---KVNAMVLIP 348
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 28.8 bits (64), Expect = 0.017 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 9e-23 Identities = 34/139 (24%), Positives = 61/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFDVEVFERGLPVLDKARQQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+DV + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.006 Identities = 41/182 (22%), Positives = 72/182 (39%), Gaps = 40/182 (21%) Query: 312 LRQARLENRQEVVLTAVDVAALFR---RVSEARTVQLAE--KNITLHVM--------PTE 358 +R LE+ + ++ L R R S AR V LA+ + ++ + Sbjct: 182 IRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 359 VNVASEPALLEQALGNLL-----DNA----IDFTPESGCITLSAEVDQEYVTLKVLDTGS 409 PA+++ + +L +N I P+ G I L D VTL+V +TGS Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 410 GIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE-VARLFNGEVTLR-NVQEGGVLASL 467 N ++S+G GL V E + L+ E ++ + ++G V A + Sbjct: 302 LALK----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 468 RL 469 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122