>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 28.5 bits (63), Expect = 0.021 Identities = 12/30 (40%), Positives = 16/30 (53%) Query: 205 LRKLLKQTYDLPKSHFYTSSYWKIGCNEGE 234 +R L Q + L +S T YWKI N+G Sbjct: 173 IRHQLTQIHGLYRSSDKTGGYWKITMNDGS 202
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 43.6 bits (103), Expect = 1e-06 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 8/56 (14%) Query: 348 LAGLTLNAAKALGIEESVGSLVVGKQADFCLWDIATPAQLAYSYGVNPCKDVVKNG 403 +A T+N A A G+ +GSL VGK+AD LW+ PA +GV P V+ G Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN---PAF----FGVKP-DMVLLGG 453 Score = 31.6 bits (72), Expect = 0.007 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 23 YGAITNAAIAVKDGKIAWLGPRSE---LPAFDVL---SIPVYRGKGGWITPGLIDAHTHL 76 + I A I +KDG+IA +G P ++ V G+G +T G +D+H H Sbjct: 80 HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139 Query: 77 V 77 + Sbjct: 140 I 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 43.4 bits (102), Expect = 6e-08 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 3/93 (3%) Query: 57 QQVSYREQYPHAISYILFYQQQAVGKLMLDLNEHRVHLVDFI-ITPSMRGRGLGSAVLEA 115 VSY E+ A ++ + + +G++ + N + L++ I + R +G+G+A+L Sbjct: 55 MDVSYVEEEGKAA-FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHK 113 Query: 116 VKLEASQRQLP-VHLSVESENTQAKSLYLRHGF 147 A + + L + N A Y +H F Sbjct: 114 AIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 44.5 bits (105), Expect = 6e-06 Identities = 40/189 (21%), Positives = 57/189 (30%), Gaps = 42/189 (22%) Query: 3348 ALGSLLLLSVTQQA-QATDWYVEGFIGQAQADKTLPELNVQVGEGQLINVDDSDTAFGVS 3406 A+ +V Q A + WY +G +Q T N ++ G Sbjct: 9 AVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTH-------ENQLGAGAF 61 Query: 3407 LGYQWTPTVALELGYADFG---------EGSAKIKGATLTPEQYHELVKTVTPVLADGVM 3457 GYQ P V E+GY G G+ K +G LT K P+ D + Sbjct: 62 GGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTA-------KLGYPITDDLDI 114 Query: 3458 LGLRFTLLQHQGWRFEVPVGLFHWQADISSTMGNTRIKTDLDGTDWYAGVRFSYQFSDAW 3517 +G W+AD T N K G Y + Sbjct: 115 YT---------------RLGGMVWRAD---TKSNVYGKNHDTGVSPVFAGGVEYAITPEI 156 Query: 3518 SVGLGYQYI 3526 + L YQ+ Sbjct: 157 ATRLEYQWT 165
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 31.1 bits (70), Expect = 0.013 Identities = 17/119 (14%), Positives = 34/119 (28%), Gaps = 12/119 (10%) Query: 608 TNLHLVRSEVKDEDRWNDETVTYASPSKATAFIGWRGETQKIRLQAEHSFSAESD---YR 664 TN H+V + D + S + ++I +S E D + Sbjct: 116 TNKHVVDATHGDPHA----LKAFPSAINQDNYPNGGFTAEQI-----TKYSGEGDLAIVK 166 Query: 665 FKTDDGLASELDSYTTLDLLGSIDLPVGTLSYGIENLLDKDYSTLWGQRAVYFYSPTYG 723 F ++ + + + + V DK +T+W + Y Sbjct: 167 FSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEA 225
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 175 bits (444), Expect = 3e-49 Identities = 102/447 (22%), Positives = 173/447 (38%), Gaps = 87/447 (19%) Query: 4 NLRNIAIIAHVDHGKTTLVDKLLSQSGTLATRGEATE--RVMDSNDLEKERGITILAKNT 61 + NI ++AHVD GKTTL + LL SG + G + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVLSMVDSVLLLVDAVDGPMPQTRFVTKKAFAQGL 121 + +W + ++NI+DTPGH DF EV R LS++D +LL+ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKIDRPGARPDWVIDQVFD-------------LFDNLGATDEQLD--------- 159 I INKID+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPVVYASALNGFATLDPDEVGTDMTPLF 187 FPV + SA N +G D L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNN--------IGID--NLI 231 Query: 188 QTIVEKVSSPAADAEGPFQMQISQLDYNSYVGVIGVGRIKRGSIKTNQQVTVIGADGKTR 247 + I K S + ++ +++Y+ + R+ G + V + + Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKI 291 Query: 248 NGKMGQVLGYMGLERTEVDVANAGDIVAITGLGELKISDTVCAAGNVEALPP---LSVDE 304 + G E ++D A +G+IV + LK++ + G+ + LP + Sbjct: 292 TEMYTSING----ELCKIDKAYSGEIVILQNEF-LKLNSVL---GDTKLLPQRERIENPL 343 Query: 305 PTLTMTFQVNTSPFAGKEGKYVTSRNILERLQQELVHNVALRVEETDSPDRFAVSGRGEL 364 P L T + + +L+ L + + LR + +S G++ Sbjct: 344 PLLQTTVEPSKPQQREM---------LLDALLEISDSDPLLRYYVDSATHEIILSFLGKV 394 Query: 365 HLSILIENMRRE-GYELAVSRPEVILK 390 + + ++ + E+ + P VI Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYM 421 Score = 37.5 bits (87), Expect = 1e-04 Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Query: 389 LKTIDGELCEPYETLTVDVEEEHQGTVIEKLGVRKAEMKDMQLDGKGRVRVDFIIPSRGL 448 LK EL EPY + + +E+ A + D QL V + IP+R + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCI 586 Query: 449 IGFQTEFLTATSGTGLIYHSFDHYGPHKG 477 ++++ T+G + Y G Sbjct: 587 QEYRSDLTFFTNGRSVCLTELKGYHVTTG 615
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (271), Expect = 1e-30 Identities = 73/240 (30%), Positives = 114/240 (47%), Gaps = 14/240 (5%) Query: 6 KTAVVTGAAGGIGQAIIRKLLAEGARVVAADLSADALKVFNDFPADKLVT---FSVDVTD 62 K A +TGAA GIG+A+ R L ++GA + A D + + L+ + F DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 YKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGILAG 122 ++ + + G +DIL+N AG+ L L+ ++E +VN GV++ + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 GRQFQAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAALELAPLGVRVCAVA 182 + + S G I+ S A + Y SKAA M TKC LELA +R V+ Sbjct: 128 SKYMMDRRS-GSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGRVDTPMLRQY--EALGLWEHIR--KEQMR-----QEFTQPNEIADVVAFLVSDEANCI 233 PG +T M + G + I+ E + ++ +P++IAD V FLVS +A I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 69 EHAEIKSMRTAATYKQQGIASKVLQHLINDAKAAGVQRLSLETGSMAFFQPARNLYAKFG 128 +A I+ + A Y+++G+ + +L I AK L LET + A + YAK Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINI--SACHFYAKHH 145 Query: 129 FELCG 133 F + Sbjct: 146 FIIGA 150
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (266), Expect = 5e-30 Identities = 71/248 (28%), Positives = 114/248 (45%), Gaps = 15/248 (6%) Query: 5 VLVTGSSRGIGKAIALKLAAAGYDIALHYHSNQAAADASAAELSALGVNVSLLKFDVADR 64 +TG+++GIG+A+A LA+ G IA N + + L A + DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 65 AAVKAAIEADIEANGAYYGVILNAGINRDNAFPAMSEAEWDSVIHTNLDGFYNVIHPCVM 124 AA+ G ++ AG+ R ++S+ EW++ N G +N V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS-VS 128 Query: 125 PMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGLIGATKALSLELAKRKITVNCIAPG 184 + R+ G I+T+ S Y++SKA + TK L LELA+ I N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 LIETDM----------VADIPKDMVEQL---VPMRRMGKPNEIAALAAFLMSDDAAYITR 231 ETDM + K +E +P++++ KP++IA FL+S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 232 QVISVNGG 239 + V+GG Sbjct: 249 HNLCVDGG 256
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 28.5 bits (63), Expect = 0.023 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 3/71 (4%) Query: 72 PKIQGNSQQGDSKAGVSSPQSFSQKVSIKVGDNTHELLTQLELE---GERMTLVGLAPLG 128 P+ +S GDSKA ++ +Q S + G H +L Q LE G+R Sbjct: 138 PRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPS 197 Query: 129 QALFTLVYDGN 139 LF + GN Sbjct: 198 YNLFGVKASGN 208
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 39.4 bits (92), Expect = 6e-05 Identities = 33/152 (21%), Positives = 58/152 (38%), Gaps = 23/152 (15%) Query: 691 TLKLLGLALVIALLLFSLSFGVKRAALVV--AVPALAALLTLAILGLAGSPLSLFHALAL 748 +K L A+++ L+ L RA L+ AVP + L T AIL G ++ + Sbjct: 340 VVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVP-VVLLGTFAILAAFGYSINTLTMFGM 398 Query: 749 ILVFGIGIDYS---------------LFFASAAQHG-KAVMMAVFMSACSTLLAFGLLAF 792 +L G+ +D + L A + + A+ A F +AF Sbjct: 399 VLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAF 458 Query: 793 SQTQA---IHYFGLTLSLGIGFTFVLSPLILT 821 F +T+ + + +++ LILT Sbjct: 459 FGGSTGAIYRQFSITIVSAMALSVLVA-LILT 489 Score = 32.1 bits (73), Expect = 0.010 Identities = 22/117 (18%), Positives = 43/117 (36%), Gaps = 17/117 (14%) Query: 694 LLGLA-LVIALLLFSLSFGVKRAALVVAVPALAALLTLAILGLAGSPLSLFHALALILVF 752 L+ ++ +V+ L L +L V+ V L + L L ++ + L+ Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 753 GIGIDYSLFFASAA-----QHGKAVMMAV-----------FMSACSTLLAFGLLAFS 793 G+ ++ A + GK V+ A M++ + +L LA S Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS 991
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 26.2 bits (57), Expect = 0.015 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Query: 1 MQNREQILAMLTTILVDEFEIDADAITTEAN--LYQELDLDSIDAVDLVIKLQQL--TGK 56 M+N + +L + T L+ +AD++TT + + +DL S+ DL +L + GK Sbjct: 9 MKNVKLLLMLGTAALLAACSNEADSLTTSIDAPVTASIDLQSVSYTDLATQLNDVSDFGK 68 Query: 57 KIQPDEFKSVRTVN 70 I + R V+ Sbjct: 69 MIILKDNGFNRQVH 82
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 88.1 bits (218), Expect = 5e-23 Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 12/118 (10%) Query: 77 NVLFPNDSAYIAPEYYPQIEEIAMFLRQY--PTTKVTIEGHTSRTGTDERNAVLSQERAD 134 +VLF + A + PE ++++ L V + G+T R G+D N LS+ RA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 135 AVTAVLADRFSIDRSRLTAIGYGSSRPLVLEHTPDAETR---------NRRVVAEVTG 183 +V L + I +++A G G S P+ + + R +RRV EV G Sbjct: 280 SVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 314 bits (805), Expect = e-104 Identities = 92/432 (21%), Positives = 197/432 (45%), Gaps = 11/432 (2%) Query: 29 RLIIWALAAMVACFLLWAGFAKLDKVTTGSGKVIPSSQVQVIQSLDGGIMQELFVREGDI 88 RL+ + + + + + +++ V T +GK+ S + + I+ ++ I++E+ V+EG+ Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 89 VTKGQPLVRIDDTRFRSDFAQQEQEVLGLKTNAIRMRAELDSILISDMTSDWREQVKITK 148 V KG L+++ +D + + +L + R + SI E K+ + Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSI----------ELNKLPE 167 Query: 149 KALVFPDSITEAEPALVRRQQEEYNGRLDNLSNQLEILVRQIQQRQQEIDDLASKTTTLT 208 L V R + NQ + +++ E + ++ Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 209 TSMQLISRELELTRPLAKKGIVPEVELLKLERAVNDAQGELNSLRLLRPKLKAALDEAIL 268 ++ L+ L K + + +L+ E +A EL + ++++ + A Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 269 KRREAVFVYAADLRAQLNETQTRLSRMNEAQVGAQDKVSKAVITSPVNGTIKTVHINTLG 328 + + ++ ++ +L +T + + +++ +VI +PV+ ++ + ++T G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 329 GVVQPGVDIIEIVPSEDQLLIETKILPKDIAFLHTGLPAVVKVTAYDFTRYGGLKGTVEH 388 GVV ++ IVP +D L + + KDI F++ G A++KV A+ +TRYG L G V++ Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 389 ISADTSQDDEGNSFYLIKVRTEESSLIKDDGTQMPIIPGMLTTVDVITGQRSILEYILNP 448 I+ D +D + + + EE+ L +P+ GM T ++ TG RS++ Y+L+P Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLS-TGNKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Query: 449 ILRAKDTALRER 460 + + +LRER Sbjct: 467 LEESVTESLRER 478
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 91.2 bits (226), Expect = 3e-20 Identities = 46/123 (37%), Positives = 60/123 (48%), Gaps = 2/123 (1%) Query: 5622 HSDEFDQSGANDKADIILGGAGNDILFGQGGNDYLDGGAGKDTLYGGNGNDTLIGGAGND 5681 +D FD SG ++ I L + G GN + G + GG+GND L+G + ++ Sbjct: 300 GTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADN 359 Query: 5682 TLIGGAGNDTLIGGLGDDVLRGDSGNDTFVWRYADADK--GTDHIMDFNVSEDKLDLSDL 5739 L GGAGND L GG G D L G +G DTFV+ D I DF DK+DLS Sbjct: 360 ILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAF 419 Query: 5740 LQG 5742 Sbjct: 420 RNE 422 Score = 53.1 bits (127), Expect = 3e-08 Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 3/90 (3%) Query: 4974 NGDFTHQPFNTGAKQTDASSGQDTVYGSNGNDHIVSTNGGGDHLLGYAGNDVLVGGDAIQ 5033 F ++ + V G GN I ++ +G +GND+LVG A Sbjct: 301 TDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTI-ENAIGGSGNDILVGNSA-- 357 Query: 5034 GDTINGGTGNDILVAGLGQDSLYGGEGNDI 5063 + + GG GND+L G G D+LYGG G D Sbjct: 358 DNILQGGAGNDVLYGGAGADTLYGGAGRDT 387 Score = 49.2 bits (117), Expect = 5e-07 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Query: 4983 NTGAKQTDASSGQDTVYGSNGNDHIVSTNGGGDHLLGYAGNDVLVGGDAIQGDTINGGTG 5042 G ++ ++ + +G D L+G + +++L GG D + GG G Sbjct: 319 EGSFSDVGGLKGNVSIAHGVTIENAIGGSGN-DILVGNSADNILQGGAG--NDVLYGGAG 375 Query: 5043 NDILVAGLGQDSLYGGEGND 5062 D L G G+D+ G G D Sbjct: 376 ADTLYGGAGRDTFVYGSGQD 395 Score = 35.3 bits (81), Expect = 0.007 Identities = 17/82 (20%), Positives = 25/82 (30%), Gaps = 2/82 (2%) Query: 4982 FNTGAKQTDASSGQDTVYGSNGNDHIVSTNGGGDHLLGYAGNDVLVGGDAIQGDTINGGT 5041 F T + A G S + G+ VGG +I G Sbjct: 281 FYTATDSSKALIFSVWDAGGTDTFD-FSGYSNNQRINLNEGSFSDVGGLK-GNVSIAHGV 338 Query: 5042 GNDILVAGLGQDSLYGGEGNDI 5063 + + G G D L G ++I Sbjct: 339 TIENAIGGSGNDILVGNSADNI 360 Score = 33.8 bits (77), Expect = 0.023 Identities = 16/75 (21%), Positives = 22/75 (29%), Gaps = 1/75 (1%) Query: 4991 ASSGQDTVYGSNGNDHIVSTNGGGDHLLGYAGNDVLVGGDAIQGDTINGGTGNDILVAGL 5050 +S + + G GND + G D L G AG D V G D Sbjct: 354 GNSADNILQGGAGNDVLYG-GAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGID 412 Query: 5051 GQDSLYGGEGNDIAV 5065 D ++ Sbjct: 413 KIDLSAFRNEGQLSF 427 Score = 33.4 bits (76), Expect = 0.032 Identities = 15/72 (20%), Positives = 22/72 (30%), Gaps = 1/72 (1%) Query: 4983 NTGAKQTDASSGQDTVYGSNGNDHIVSTNGGGDHLLGYAGNDVLVGGDAIQGDTINGGTG 5042 N+ +G D +YG G D + G D + +G D V D G Sbjct: 355 NSADNILQGGAGNDVLYGGAGADTL-YGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDK 413 Query: 5043 NDILVAGLGQDS 5054 D+ Sbjct: 414 IDLSAFRNEGQL 425
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 332 bits (853), Expect = e-117 Identities = 165/304 (54%), Positives = 203/304 (66%), Gaps = 15/304 (4%) Query: 6 ISLLSHSLAQSPWLFITLSFVFAATIGSFLNVVIHRFPVMMKREWQQECNQYLQEYHADV 65 ++LL PWL+ +L F+F+ IGSFLNVVIHR P+M++REWQ E Y Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPD---- 56 Query: 66 VEQIGIEKLNKPIDTYPEKYNLVVPGSACPKCKTAIKPWHNLPIVGWLMLRGKCAACNTA 125 YNL+VP S CP C I N+P++ WL LRG+C C Sbjct: 57 -----------DEGVDEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAP 105 Query: 126 ISSRYPIIELVTGLLVATLAWHFGPSWQFVFAAVLTFVLIALTGIDLDEMLLPDQMTLPL 185 IS+RYP++EL+T LL +A P W + A +LT+VL+ALT IDLD+MLLPDQ+TLPL Sbjct: 106 ISARYPLVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPL 165 Query: 186 LWLGLLINLNHTFTTPTDAVIGAAAGYLSLWSVFWLFKLLTGKEGMGYGDFKLLAVFGAW 245 LW GLL NL F + DAVIGA AGYL LWS++W FKLLTGKEGMGYGDFKLLA GAW Sbjct: 166 LWGGLLFNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAW 225 Query: 246 LGWQMLPLVILLSSLVGALVGITLIVLKRNQLANPIPFGPYIAAAGWIALIWGQPIVDWY 305 LGWQ LP+V+LLSSLVGA +GI LI+L+ + + PIPFGPY+A AGWIAL+WG I WY Sbjct: 226 LGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWY 285 Query: 306 LSTL 309 L+ Sbjct: 286 LTNF 289
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 391 bits (1007), Expect = e-136 Identities = 122/405 (30%), Positives = 214/405 (52%), Gaps = 9/405 (2%) Query: 25 TFEWKGLNRDGQKTSGELRGASAAEIRSQLKSQGVNP--------KTVRKQSAALFKLGD 76 + ++ L+ G+K G SA + R L+ +G+ P + S L Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 77 AKISPMDIAMITRQIATMLAAGVPLVTTIELLGRGHEKAKMRELLGSILSEIQSGIPLSD 136 ++S D+A++TRQ+AT++AA +PL ++ + + EK + +L+ ++ S++ G L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 137 SLRPHRRYFDDLYVDLVAAGEHSGSLDVVFDRIATYREKSEALKSKIKKAMFYPAAVVVV 196 +++ F+ LY +VAAGE SG LD V +R+A Y E+ + ++S+I++AM YP + VV Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 197 AILVTTLLLLFVVPQFEEIFKGFGAELPAFTQLVLHISRGLQSSWYIFLGAIVAGVFLFV 256 AI V ++LL VVP+ E F LP T++++ +S +++ L A++AG F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAF- 241 Query: 257 RAHRNSQMVRDRVDEAVLKIPAIGPILHKGAMARFARTLATTFAAGVPLIDGLESAAGAS 316 R + R +L +P IG I AR+ARTL+ A+ VPL+ + + Sbjct: 242 RVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVM 301 Query: 317 GNAVYRKAILKIRQEVMAGMQMNVAMRTTGLFPDMLIQMVMIGEESGSLDNMLNKVANIY 376 N R + V G+ ++ A+ T LFP M+ M+ GE SG LD+ML + A+ Sbjct: 302 SNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQ 361 Query: 377 EMQVDDAVDGLSSLIEPIMMVVIGTVVGGLIVAMYLPIFQMGKVV 421 + + + L EP+++V + VV +++A+ PI Q+ ++ Sbjct: 362 DREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.9 bits (93), Expect = 5e-07 Identities = 14/32 (43%), Positives = 24/32 (75%), Gaps = 1/32 (3%) Query: 5 KMNKNAQGFTLIELMIVVAIIGILAAVALPAY 36 +K +GFTL+E+M+V+ IIG+LA++ +P Sbjct: 3 ATDKQ-RGFTLLEIMVVIVIIGVLASLVVPNL 33
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 109 bits (275), Expect = 6e-28 Identities = 59/269 (21%), Positives = 87/269 (32%), Gaps = 88/269 (32%) Query: 210 TDRGPEFIGADQMWQGTATQGGLPVKGEGMVVGIIDTGINTDHVAFADDEEYARLNPYKG 269 RG E I A +W T +G G+ V ++DTG + DH Sbjct: 22 IPRGVEMIQAPAVWNQT--------RGRGVKVAVLDTGCDADHPDLKA------------ 61 Query: 270 QAIGDCGAFPELCNNKLVGLHSYPEITDVYAAPEFQTSSGAKKRIRPANAEDYAGHGSHT 329 +++G ++ + + P +DY GHG+H Sbjct: 62 ---------------RIIGGRNFTDDDE----------------GDPEIFKDYNGHGTHV 90 Query: 330 ASTVAGNTLKDTPLQGFTGDKVSDGVDVPFTFPQTSGVAPRAHIIAYQVCWPGTSGDPYA 389 A T+A ++ GVAP A ++ +V SG Sbjct: 91 AGTIAAT-----------ENENG-----------VVGVAPEADLLIIKVLNKQGSGQ--- 125 Query: 390 GCPESAILSAFEDAIADGVDAINFSIGGAENMPWGDPMELAFLSAREAGISVAAAAGNSG 449 I+ AI VD I+ S+GG E+ + A A + I V AAGN G Sbjct: 126 ---YDWIIQGIYYAIEQKVDIISMSLGGPED---VPELHEAVKKAVASQILVMCAAGNEG 179 Query: 450 AYWTADH------SSPWVTTVGATTHDRK 472 V +VGA DR Sbjct: 180 DGDDRTDELGYPGCYNEVISVGAINFDRH 208 Score = 72.6 bits (178), Expect = 2e-15 Identities = 32/131 (24%), Positives = 48/131 (36%), Gaps = 32/131 (24%) Query: 627 NNLATFSSLGPSKTNNTLVPDLTAPGVDIYAANADDQPFTNNPSASDWTFMSGTSMAAPH 686 + + FS+ DL APG DI + + SGTSMA PH Sbjct: 207 RHASEFSNSNNE-------VDLVAPGEDILSTVPG----------GKYATFSGTSMATPH 249 Query: 687 VTGAMTLLTQL-----HPDWTPAEIQSALMLTAGPVVLNTGYELVEPYYNFMAGAGAINV 741 V GA+ L+ QL D T E+ + L+ P+ + E G G + + Sbjct: 250 VAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKME----------GNGLLYL 299 Query: 742 ARAADTGLVMD 752 + + D Sbjct: 300 TAVEELSRIFD 310
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 5e-04 Identities = 21/80 (26%), Positives = 31/80 (38%), Gaps = 2/80 (2%) Query: 145 PMAYDDTPVAVSPPVRVTTSMQYSPSEGRMVSNMPTNSATVISQTGVSTTRASTASAEQM 204 P + +T P + T+S P N NS + T T ++E Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVN-TGNSVVENPENTTPATTQPTVNSE-S 1215 Query: 205 ANVPRARAARSVSSLPSNAR 224 +N P+ R RSV S+P N Sbjct: 1216 SNKPKNRHRRSVRSVPHNVE 1235
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.0 bits (122), Expect = 4e-09 Identities = 60/322 (18%), Positives = 106/322 (32%), Gaps = 22/322 (6%) Query: 52 VAHVSYAISAYALGVVVGSPIIMVLGVRIKRRTLLIALAAMMAVANGLSALAPSLNWLVF 111 AH ++ YAL +P++ L R RR +L+ A AV + A AP L L Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYI 101 Query: 112 FRFLSGLPHGAYFGVAMLLAASLVPPEMKARAVSRVIIGLTLATIVGVPFATWMGQTVGW 171 R ++G+ GA VA A + + +AR + + G MG Sbjct: 102 GRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSP 159 Query: 172 RSGIGIVAIIAAVTAVMLYFLAPNVAVPQNASPKKELQTLKNREVWLTLGIAAIGFGGIF 231 + A + + + FL P + + N + Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPE---SHKGERRPLRREALNPLASFRWARGMTVVAALM 216 Query: 232 CVYTYLAETLIQVTQV------------EPFKIPVMMAVFGI-GATLGTLVCGWAADK-S 277 V+ ++ + + QV + I + +A FGI + ++ G A + Sbjct: 217 AVF-FIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLG 275 Query: 278 ALAAAFWSLVLSTLVLALYPSLTGSYWALMPI-VFFVGSGIGLATTVQARLMDVAPDGQA 336 A ++ L + W PI V GIG+ V + Q Sbjct: 276 ERRALMLGMIADGTGYILL-AFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 337 MTGALVQCAFNLANAIGPWVGS 358 + +L + +GP + + Sbjct: 335 QLQGSLAALTSLTSIVGPLLFT 356
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 53.9 bits (129), Expect = 7e-11 Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 5/183 (2%) Query: 2 ILITGASSGLGAALAALYAKDNQALTLTGRDANRLHTVANALSPFSTQSISAISADLADE 61 ITGA+ G+G A+A A + + +L V ++L + + A AD+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRDS 69 Query: 62 ASVEALFDGL---TDTPNTVIHCAGSGYFGTLETQGTSEIQALLNNNVTSTILLVRELVK 118 A+++ + + + +++ AG G + + E +A + N T R + K Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 119 RYK-QQAVKVVIVMSTAALTAKAGESTYCAAKWAVRGFIESVRLELKQSPMKLIAVYPGG 177 +++ +V V S A + + Y ++K A F + + LEL + ++ V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 MDT 180 +T Sbjct: 190 TET 192
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.002 Identities = 10/32 (31%), Positives = 14/32 (43%) Query: 120 IEAKRDGIVGAIWVKDGDEVAFDQPLFTLIET 151 I+ + IV I VK+G+ V L L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTAL 130
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.002 Identities = 16/154 (10%), Positives = 45/154 (29%), Gaps = 12/154 (7%) Query: 76 EVQAQIARQQQAELAIAAADRAIYNPEL-GLNYQNADTDTYSLGLSQTLDWGDKRGVATR 134 + + QA L + EL L + Y +S+ + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 135 LAQLEAQILLADIQLERSQMLAERLLALAEQAQSNKALTFAEQQLRFTQAQLNIAEQRFA 194 + + Q ++ L++ + AE+ + E R +++L+ Sbjct: 195 FSTWQNQKYQKELNLDKKR---------AERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 195 AGDLSDVELQLLKLELASNTADYALAEQAALVAD 228 ++ + + + + L + + Sbjct: 246 KQAIAKHAVLEQENKYVEAVNE--LRVYKSQLEQ 277
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 1e-10 Identities = 31/138 (22%), Positives = 55/138 (39%), Gaps = 9/138 (6%) Query: 156 EVAKAQAEYINAAAEWSRVRR---MSEGAVSVSRRMQAQVDAELKRAILEAIKMTDAQIR 212 V + + +Y+ A E + E + ++ V K IL+ ++ T I Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 213 TLE----STPEAIGSYQLLAPIDGRVQQ-DIAMLGQVFTAGTPLMQLT-DESHLWVEAQL 266 L E + + AP+ +VQQ + G V T LM + ++ L V A + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 267 TPAQAANVNVGGPALVQV 284 +NVG A+++V Sbjct: 373 QNKDIGFINVGQNAIIKV 390 Score = 42.9 bits (101), Expect = 2e-06 Identities = 26/149 (17%), Positives = 54/149 (36%), Gaps = 5/149 (3%) Query: 100 SFSNLNLDTMATATLVVDRDRTATLAPQLDVRVQARHVVPGQEVKKGEPLLTLGG----A 155 + + A L R+ + P + V+ V G+ V+KG+ LL L A Sbjct: 76 VLGQVEIVATANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134 Query: 156 EVAKAQAEYINAAAEWSRVRRMSEGAVSVSRRMQAQVDAELKRAILEAIKMTDAQIRTLE 215 + K Q+ + A E +R + +S D + + E + + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 216 STPEAIGSYQLLAPIDGRVQQDIAMLGQV 244 + YQ +D + + + +L ++ Sbjct: 195 FSTWQNQKYQKELNLDKKRAERLTVLARI 223
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 654 bits (1690), Expect = 0.0 Identities = 224/1077 (20%), Positives = 438/1077 (40%), Gaps = 72/1077 (6%) Query: 9 AIKNRLLVVLALLAVVAASVAMLPKLNLDAFPDVTNVQVTINTAAEGLAAEEVEKLISYP 68 I+ + + + ++ A + +L + +P + V+++ G A+ V+ ++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 69 VESAMYALPAVTEVRSLS-RTGLSIVTVVFAEGTDIYFARQQVFEQLQAAREMIPSGVGV 127 +E M + + + S S G +T+ F GTD A+ QV +LQ A ++P V Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 128 PEIGPNTSGLGQIYQYILRADPSSGINAAELRSLNDYLVKLIMMPVGGVTDVLSFGGEVR 187 I S + +D + G ++ VK + + GV DV FG + Sbjct: 125 QGISVEKSSSSYLMVAGFVSD-NPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ-Y 182 Query: 188 QYQVQVDPNKLRAYGLSMAQVSEALESNNRNAGGWFMDQGQEQLVVRGYGMLPAGEAGLA 247 ++ +D + L Y L+ V L+ N + G L + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLG-GTPALPGQQLNASIIAQTRFK 241 Query: 248 AIAQIPLTEVR----GTPVRVGDIAQVDFGSEIRVGAVTMTRRDEAGQAQDLGEVVAGVV 303 + +R G+ VR+ D+A+V+ G E + G+ + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-----GK-----PAAGLGI 291 Query: 304 LKRMGANTKATIDDIDARINLIEQALPKGVSFEVFYDQADLVDKAVTTVRDALLMAFVFI 363 GAN T I A++ ++ P+G+ YD V ++ V L A + + Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 364 VVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVAIGMLVDGSVV 423 +++ LFL N+RATL+ +++PV + +++ +G S N +++ G+ +AIG+LVD ++V Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 424 MVENIFKHLTQPDRRHLAQARSRADGEVDPYHGDEDGSAHAVEADNNMAVRIMLAAKEVC 483 +VEN+ R + ++ P + ++ Sbjct: 412 VVENV--------------ERVMMEDKLPPKEA------------------TEKSMSQIQ 439 Query: 484 SPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAVPALAVYLFK- 542 + ++ VF P+ G G +++ +++I+ AM ++LVALI PAL L K Sbjct: 440 GALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKP 499 Query: 543 ---------RGVVLKESVVLAPLDSAYRKLLSATLARPKLVMTSALLMFAMSMVLLPRLG 593 G + + Y + L + L+ A +VL RL Sbjct: 500 VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLP 559 Query: 594 TEFVPELEEGTINLRVTLAPTASLGTSLDVAPKLEAMLLEFPEVEYALSRIGAPELGGDP 653 + F+PE ++G + L A+ + V ++ L+ + S Sbjct: 560 SSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVE-SVFTVNGFSFSG 618 Query: 654 EPVSNIEVYIGLKPIEEWQSASSRLE--LQRLMEEKLSVFPGLLLTFSQPIATRVDELLS 711 + + ++ LKP EE + E + R E + G ++ F+ P + EL + Sbjct: 619 QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGT 675 Query: 712 GVKAQLA-IKLFGPDLDVLSEKGQVLTDLVAKIPGAV-DVSLEQVSGEAQLVVRPDRAQL 769 I G D L++ L + A+ P ++ V + AQ + D+ + Sbjct: 676 ATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKA 735 Query: 770 ARYGISVDQVMSLVSQGIGGASAGQVIDGNARYDINLRLAAQYRSSPDVIKDLLLSGSNG 829 G+S+ + +S +GG ID + ++ A++R P+ + L + +NG Sbjct: 736 QALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANG 795 Query: 830 ATVRLGEVASVEVEMAPPNIRRDDVQRRVVVQANVA-GRDMGSVVKDIYALVPQADLPAG 888 V + P + R + + +Q A G G + + L + LPAG Sbjct: 796 EMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAG 853 Query: 889 YTVIVGGQYENQQRAQQKLMLVVPISIALIALLLYFSFGAVKQVLLIMANVPLALIGGIV 948 G ++ + + +V IS ++ L L + + + +M VPL ++G ++ Sbjct: 854 IGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLL 913 Query: 949 ALFVSGTYLSVPSSIGFITLFGVAVLNGVVLVDSINQ-RRQSGESLYDSVYEGTVGRLRP 1007 A + V +G +T G++ N +++V+ + G+ + ++ RLRP Sbjct: 914 AATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRP 973 Query: 1008 VLMTALTSALGLIPILVSSGVGSEIQKPLAVVIIGGLFSSTALTLLVLPTLYRWLYR 1064 +LMT+L LG++P+ +S+G GS Q + + ++GG+ S+T L + +P + + R Sbjct: 974 ILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 106 bits (266), Expect = 2e-25 Identities = 85/550 (15%), Positives = 186/550 (33%), Gaps = 68/550 (12%) Query: 10 IKNRLLVVLALLAVVAASVAMLPKLNLDAFPDVTNVQVTIN-TAAEGLAAEEVEKLI--- 65 + + +L +VA V + +L P+ G E +K++ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 66 -SYPVESAMYALPAVTEVRSLSRTGLS----IVTVVFAEGTDIYFARQQVFEQLQAAREM 120 Y +++ + +V V S +G + + V + + A+ Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME 653 Query: 121 ---IPSGVGVPEIGPNTSGLGQIYQYILRADPSSGINAAELRSLNDYLVKLIMMPVGGVT 177 I G +P P LG + +G+ L + L+ + + Sbjct: 654 LGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 178 DVLSFGGEVR-QYQVQVDPNKLRAYGLSMAQVSEALES--NNRNAGGWFMDQGQEQLVVR 234 V G E Q++++VD K +A G+S++ +++ + + + ++L V+ Sbjct: 714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQ 773 Query: 235 GYGMLPAGEA-GLAAIAQIPLTEVRGTPVRVGDIAQVDFGSEIRVGAVTMTRRDEAGQAQ 293 A + ++ + G V + G+ + R + + Sbjct: 774 ----ADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVY----GSPRLERYNGLPSME 825 Query: 294 DLGEVVAGVVLKRMGANTKATIDDIDARINLIEQALPKGVSFEVFYDQADLVDKAVTTVR 353 GE G D A + + LP G+ ++ + + + Sbjct: 826 IQGEAAPGTSS-----------GDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAP 873 Query: 354 DALLMAFVFIVVILALFLVNIRATLLVLLSIPVSIGLALMVMSYYGLSANLMSLGGLAVA 413 + ++FV + + LA + + V+L +P+ I L+ + + ++ + GL Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 414 IGMLVDGSVVMVENIFKHLTQPDRRHLAQARSRADGEVDPYHGDEDGSAHAVEADNNMAV 473 IG+ ++++VE A+ +G+ VEA Sbjct: 934 IGLSAKNAILIVE-------------FAKDLMEKEGK------------GVVEA------ 962 Query: 474 RIMLAAKEVCSPIFFATAIIIVVFAPLFALEGVEGKLFQPMAVSIILAMISALLVALIAV 533 ++A + PI + I+ PL G + + ++ M+SA L+A+ V Sbjct: 963 -TLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 534 PALAVYLFKR 543 P V + + Sbjct: 1022 PVFFVVIRRC 1031
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 28.9 bits (64), Expect = 0.036 Identities = 17/98 (17%), Positives = 39/98 (39%), Gaps = 16/98 (16%) Query: 248 ASDITQRIIKSHAIRDAANIAHATSQSTVEQANRGVQLLDATVNTSNAIAAQTHKTTESM 307 ++ +T+ +I +H ++ ++H+ Q + AT+ + + + + S Sbjct: 23 SATLTEGVIGAHRVKVETALSHSNLQKKLS----------ATIKHNQSGRSMLDRKLTSD 72 Query: 308 LKLNEQSQSIQAIVATISAIADQTNLLALNAAIEAARA 345 K N++S T S I + L+ + A R Sbjct: 73 GKANQRSSF------TFSMIMYRMIHFVLSTRVPAVRE 104
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.003 Identities = 32/195 (16%), Positives = 74/195 (37%), Gaps = 33/195 (16%) Query: 468 LQSVLTLIQQEVSRADSIISRLRNLLKK--RPVSKQLLYLHQLVNDTAPLLAY-ELEQ-- 522 L ++ LI ++ ++A +++ L L++ R + + + L + + +Y +L Sbjct: 179 LNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTV---VDSYLQLASIQ 235 Query: 523 --HHIQLSTNVSGEAYQLPLDEVGMQQLLLNLLKNAADACVQRQQSEVDASKPYQPTIDI 580 +Q ++ + + + +Q L+ N +K+ A P I + Sbjct: 236 FEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGI------------AQLPQGGKILL 283 Query: 581 DLRYQEHKLLLTVTDNGTGLTEDANLLMQAFYSTKSEGLGLGLVICRDIAESHGGRFSLE 640 + L V + G+ ++ + +S G GL V R + +G ++ Sbjct: 284 KGTKDNGTVTLEVENTGSLALKN---------TKESTGTGLQNVRER-LQMLYGTEAQIK 333 Query: 641 -TALSGGCQAQVSLP 654 + G A V +P Sbjct: 334 LSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 97.2 bits (242), Expect = 8e-26 Identities = 29/119 (24%), Positives = 52/119 (43%) Query: 7 VYLIDDDESVRRSLRFMLESYGLNIRDFDSAEAFFAAIDLSQPGCALVDVRMPGLSGPQL 66 + + DDD ++R L L G ++R +A + I + DV MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 HAQLVQHNSPLAVIYLTGHGDVPMAVEALKLGAVDFFQKPADGAKLADAVVKALEHAKA 125 ++ + L V+ ++ A++A + GA D+ KP D +L + +AL K Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 52.0 bits (124), Expect = 1e-08 Identities = 53/316 (16%), Positives = 102/316 (32%), Gaps = 10/316 (3%) Query: 598 EYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRD 657 EL LS A+E L+ + +E S++ + L + L A Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSA 141 Query: 658 DLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQLWLEEQKEQALEAR 717 ++ L EK + KA K + + E ++ LE Sbjct: 142 KIKTLEAEK---AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 718 MEKQAYWQEVIGALDNQLGQIKATIDARRESAKAEQKACETWYKNELKSRGVDEDNILKL 777 +E + A L KA + AR+ + + + + E L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 778 KQQIRELETKISRAEQRRSEVLRFDDWY-----QHTWLIRKPKLQTQLSDVKR-AASEID 831 + + ELE + A + + Q+Q+ + R + Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 832 QQLKAKTQEVKTRRQQLETERKASDAAQIEASENLTKLRAVMRKLAELKLPANNEEAQGS 891 + ++++ Q+LE + K S+A++ +L R ++L E + E+ + S Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL-EAEHQKLEEQNKIS 377 Query: 892 LGERLRQGEDLLLKRD 907 R DL R+ Sbjct: 378 EASRQSLRRDLDASRE 393 Score = 33.5 bits (76), Expect = 0.006 Identities = 50/346 (14%), Positives = 112/346 (32%), Gaps = 27/346 (7%) Query: 360 WRADMENLSERHKLQTEKHQDIEAAYNARRSKIGEQLNRELEGLHAEQDKQREARDKQRE 419 + + + K+ D+ A + N EL + ++ DK Sbjct: 55 VQERADKFEIENNTLKLKNSDLSFNNKAL-----KDHNDELTEELSNAKEKLRKNDKSLS 109 Query: 420 VARADLDALEAQWRSQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLSLAIFDE 479 + + LEA + D KA + +A L + + ++ Sbjct: 110 EKASKIQELEA---RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL----EK 162 Query: 480 RIHRADEEQESCNAKVERLTGEERKLRAKRDQANEALRIASLRVNERQTALDELHHMLFP 539 + A + +AK++ L E+ L A++ + +AL A + L Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 222 Query: 540 QSHTL--LEFLRKEAQGWEQSLGKVIAPELLHRTDLHPTVTGESDTVFGVHLDLKAIDVP 597 + LE + A + + I + L + Sbjct: 223 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL------------E 270 Query: 598 EYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRD 657 ++ E + + +A+ E Q +N L R+L +R A K Sbjct: 271 GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330 Query: 658 DLRRLFDEKRSEQDKINKALAERKAFAQQRLTQLDGELKQLKHQHQ 703 + ++L ++ + + ++L +++ QL+ E ++L+ Q++ Sbjct: 331 EHQKLEEQNKI-SEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 70.7 bits (173), Expect = 1e-16 Identities = 46/215 (21%), Positives = 97/215 (45%), Gaps = 1/215 (0%) Query: 37 LYFLIFGNLVGSRIGDMGGVSYMEFIAPGLIMMSVITNS-YSNVASSFYSAKFQRNLEEL 95 +Y G +G +G +GGVSY F+A G++ S +T + + + ++F + QR E + Sbjct: 44 IYLFGLGAGLGVMVGRVGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAM 103 Query: 96 MVAPVPHYVMIAGYVGGGVARGLCVGLIVTLVAMFFVDISLHHAGLVVMTVFLTSVLFSL 155 + + ++ G + + G + +VA + + LT + F+ Sbjct: 104 LYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLYALPVIALTGLAFAS 163 Query: 156 GGLINAVFAKSFDDISIIPTFVLTPLTYLGGVFYSLSLLPSFWQGVSALNPVVYMINVFR 215 G++ A S+D T V+TP+ +L G + + LP +Q + P+ + I++ R Sbjct: 164 LGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIR 223 Query: 216 YGFLGFADISIPLSIGIMVGFCAVLWGVAYYLISR 250 LG + + +G + + + + ++ L+ R Sbjct: 224 PIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRR 258
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.4 bits (61), Expect = 0.047 Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 165 EGFDAAKLNQVLGLREKGLCASVVVALGYRSEEDFNAK 202 +GF L + + LRE+G +++ G+ +D Sbjct: 54 DGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIY 91
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 272 bits (696), Expect = 4e-97 Identities = 131/168 (77%), Positives = 150/168 (89%) Query: 2 PLLDSFTVDHTRMNAPAVRVAKHMSTPKGDAITVFDLRFCAPNKDILSERGIHTLEHLFA 61 PLLDSFTVDHTRMNAPAVRVAK M TPKGD ITVFDLRF APNKDILSE+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRDHLNGSDVEIIDISPMGCRTGFYMSLIGEPSERQVADAWLASMEDVLKVVEQSEIP 121 GFMR+HLNG VEIIDISPMGCRTGFYMSLIG PSE+QVADAW+A+MEDVLKV Q++IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNEYQCGTYEMHSLEQAQDIARNIIAAGVSVNRNDDLKLSDEILGQL 169 ELNEYQCGT MHSL++A+ IA+NI+ GV+VN+ND+L L + +L +L Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLREL 168
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.0 bits (119), Expect = 2e-09 Identities = 40/189 (21%), Positives = 75/189 (39%), Gaps = 10/189 (5%) Query: 12 VLITGASSGIGLQLAKDYLAAGWHVIACGRDKAKLDALAETVLIGA---TCISFDINERS 68 ITGA+ GIG +A+ + G H+ A + KL+ + ++ A D+ + + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 69 QVQENALRIKDLLTQCACQLDLVILNAGGCEYIDDAKHFDDRLFERVVHTNLIAMGFCLG 128 + E RI+ + +D+++ N G D +E N + Sbjct: 71 AIDEITARIEREMGP----IDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 129 AFLPLMP--RGARLALMSSSATYLAFPRAEAYGASKAGVQYLAASLRLDLAQHGISVSVI 186 + M R + + S+ + AY +SKA L L+LA++ I +++ Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 CPGFVATPL 195 PG T + Sbjct: 186 SPGSTETDM 194
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 31.3 bits (70), Expect = 0.019 Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 11/138 (7%) Query: 138 VLDDFAKADVLFKRTEPAPFKSVNVLAEGRRAL------EVANVEMGLALAEDEIDYLVE 191 ++ D AK V+ + K ++AEG + V + +++A E +L+E Sbjct: 102 LMSDVAKGTVVASQEATIVAKCSGMVAEGANKVVEMSKKAVQETQKAVSVA-GEATFLIE 160 Query: 192 NFVRLNRNPNDIELMMFAQ--ANSEHCRHKIFNADWTIDGEAQ-PKSLFKMIKNTFETTP 248 + LN++PN+ EL + + A E + + ++ +D Q + + M+ + Sbjct: 161 KQIMLNKSPNNKELELTKEEFAKVEQVKETLMASERALDETVQEAQKVLNMVNGLNPSNK 220 Query: 249 DHVLSAYKDNAAVMEGSV 266 D VL A KD A + V Sbjct: 221 DQVL-AKKDVAKAISNVV 237
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.8 bits (80), Expect = 3e-04 Identities = 19/106 (17%), Positives = 39/106 (36%), Gaps = 9/106 (8%) Query: 18 ADAVQQQLEQASTYEGLPFIERLSLLVEHEQLSREQRKQARLVKQARLKLQATVQEVDYQ 77 A++ + A Y PF + + L+ +R+ ++L ++ + + Q Sbjct: 88 MTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQ 147 Query: 78 SARNLERSQVANLAQGEWLRRGQNLLITGPCGCGKTYLACALGYQA 123 + ++ + L+ITG G GK +A AL Sbjct: 148 EIYRVLA-RLM--------QTDLTLMITGESGTGKELVARALHDYG 184
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 0.001 Identities = 40/281 (14%), Positives = 83/281 (29%), Gaps = 19/281 (6%) Query: 437 FYGQRPFGSDDKADPDAEDEAELDDEFGDAVNTLFSTPSTVEEKFGASEESDEAPADKEE 496 D D E+ + ++ +L S ++E + ++A Sbjct: 75 DLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMN 134 Query: 497 GPKGFLGWLSACAEVNKTRSPEQRQALWQEAIADYEAAKTEVRRTC----AAANRIRELI 552 + ++ L ++A+ T A + Sbjct: 135 FSTADSAKIKTLEAEKA-ALAARKADL-EKALEGAMNFSTADSAKIKTLEAEKAALEARQ 192 Query: 553 QALCKTRKQVAEQSEALRTLESKLADAVNQLSRL--DAEENRPASMALKQCLY------- 603 L K + S A L L+ D E+ +M Sbjct: 193 AELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 252 Query: 604 -ELEVHQARKPGFWAKVFSFWGAQRDWDAKRKRLESHHDLAKSEFSRIARLTKQLGASRE 662 E +AR+ + AK K LE+ ++E + + ++ L A+R+ Sbjct: 253 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQ 312 Query: 663 SLEKHTADTRRALQRLRSQCQ--AHMQDAIDVAREG-QADH 700 SL + +R A ++L ++ Q + +R+ + D Sbjct: 313 SLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDL 353
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 28.0 bits (62), Expect = 0.048 Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 6/44 (13%) Query: 225 QFDVPYLYRK-SGSLAQPRDFARDLRALVAKQSLP-----GYEL 262 Q ++PY + SG++ P D +LR +A+Q LP G+EL Sbjct: 71 QMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFEL 114
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 108 bits (270), Expect = 2e-27 Identities = 93/461 (20%), Positives = 189/461 (40%), Gaps = 28/461 (6%) Query: 36 LLLAGFVTIFDLFVVNVAIPSMQANLGASFAQIGFIVAGYELAFGVLLIMGGRLGDLFGR 95 L + F ++ + V+NV++P + + A ++ + L F + + G+L D G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 96 RRLFIVGMAGFTLASAMCGLAPS-AEILIVARVLQGLAAALLFPQVYASIRVNFDGDDSR 154 +RL + G+ S + + S +LI+AR +QG AA FP + + + ++R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVVVARYIPKENR 137 Query: 155 -RAFGLLGMTLGLAAIAGQVLGGWLVHADLFGLSWRTIFLINVPIGLFAITAASCIPESR 213 +AFGL+G + + G +GG + H + W + LI + I + + + + Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHY----IHWSYLLLIPM-ITIITVPFLMKLLKKE 192 Query: 214 AEQSPALDWSGVILVSSGLALLLVPLIEGPGQGWPAWSLWSLGGAVALMVTFYRYQERQR 273 D G+IL+S G+ ++ + +S+ + +++F + + R Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFMLFT-----------TSYSISFLIVSVLSFLIFVKHIR 241 Query: 274 IAGRFPLVDMQLMRQRRFALGALLVLLVYSTSSSFFLSFALLVQTGLGLDPFVAGSIFA- 332 P VD L + F +G L +++ T + F +++ L GS+ Sbjct: 242 KVTD-PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 333 PCSVGFVLASLTAPRLVALWGARAIVAGALVYAISIGLLITQVQMAGAELLPVTLIPVLI 392 P ++ ++ LV G ++ + + +S+ L + +I + Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTF-LSVSFLTASFLLETTSWFMTIII---V 356 Query: 393 IVGAGQGLIMTPLLNLVLGFVKENQAGMASGVISTVQQVGAALGVAIVGILFGTALTASN 452 V G T + +V +K+ +AG +++ + G+AIVG L L Sbjct: 357 FVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQR 416 Query: 453 GALAQADQYASAFVSGMLYNLGAALLICFL--LLILARSQR 491 + D ++ S +L ++I +L L + SQR Sbjct: 417 LLPMEVD-QSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQR 456
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 30.2 bits (68), Expect = 0.002 Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 4/69 (5%) Query: 70 SLELGAAAQPGGAIYTLEATNGGLISFGGGVVLHDELGRTIGAV---GVAGATVEADQII 126 + +G + + GG+++ GV L L T+ V G A VE + Sbjct: 679 NANIGYSHSDDIKQLYYGVS-GGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 127 ALQAAGRSL 135 G ++ Sbjct: 738 RTDWRGYAV 746
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.5 bits (139), Expect = 3e-11 Identities = 97/384 (25%), Positives = 145/384 (37%), Gaps = 27/384 (7%) Query: 16 VTAFAIGVAEFIVVGILPAIADDL---NVPLARAGGLVGLYALALAVGTPIVVLTLARLP 72 T V +++ +LP + DL N A G L+ LYAL P++ R Sbjct: 12 STVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFG 71 Query: 73 RKPLLMALVAVFLAGNLISALSASYELLLAGRILTAVAHGSFFAIGATVAARLAPKGQAS 132 R+P+L+ +A I A + +L GRI+ + G+ A+ A + + + Sbjct: 72 RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERA 130 Query: 133 RAIAMMFAGLTLAMVVGVPLGSLIGNALGWRLPFFAVAGLAGLAFLATARWVP------- 185 R M A MV G LG L+G PFFA A L GL FL +P Sbjct: 131 RHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGER 189 Query: 186 -ALPTQATGPVGTQLAALASAPILAMMAITVLG--FGASFATFTFINPILTDITGFSTHT 242 L +A P+ + A + A+MA+ + G A I D + T Sbjct: 190 RPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE--DRFHWDATT 247 Query: 243 VSLLLVVFGVA-TLVGNLAGGRWAASLGWPVALRRMLAGLLLVLVALAVALPLKWVMVPL 301 + + L FG+ +L + G AA LG AL + + LA A W+ P+ Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG-WMAFPI 306 Query: 302 LFVWGVLAFGMSPGFQAGMLETAGRWTPRAVDFASALNISAFNLGITLGETLGSGLVAQE 361 + + GM P QA + + +L +G L + + A Sbjct: 307 MVLLASGGIGM-PALQAMLSRQVDE---ERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 362 QMDMTPWA---GVALVLLAQLPLL 382 WA G AL LL LP L Sbjct: 363 ITTWNGWAWIAGAALYLLC-LPAL 385
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.4 bits (68), Expect = 0.020 Identities = 35/154 (22%), Positives = 53/154 (34%), Gaps = 23/154 (14%) Query: 254 GIFGPGIATGLVSGAPQL----GAGAMAGAAVGAVGTGVAIGAAATGVGAAVAAGARMAP 309 G FGPG ++ G + + +A + V A G AI G V+ G+ AP Sbjct: 281 GGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAI-RVGRGARVTVSGGSLSAP 339 Query: 310 AAAKLAGAGARAATSAAGNARSAFQAGSTAAGGG-------------AKGAAAGLGNVAK 356 + GAR A QAG+ A G G A G++ Sbjct: 340 HGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVA 399 Query: 357 TSAQAASRRVASGASAAGQKMTSSFRAGWNGSSD 390 T + G S + + +A W G++ Sbjct: 400 TELPS-----IPGTSIGPLDVALASQARWTGATR 428
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.0 bits (62), Expect = 0.043 Identities = 13/73 (17%), Positives = 21/73 (28%) Query: 26 PPPTISLDESVLAQPLPEPLAPVEVVAVPEPLALPAQLKPLPEVDAAPAAPEPADEKVRV 85 PP + + +P PEP E + + KP P+ +P + V Sbjct: 62 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPV 121 Query: 86 SRANAEARIAPTR 98 A Sbjct: 122 ESRPASPFENTAP 134
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.002 Identities = 35/264 (13%), Positives = 85/264 (32%), Gaps = 35/264 (13%) Query: 393 QASVQSIEQQASKAQRIAKQNGEEAQALMQQTDQIATAIEEMSTSIRDVANHAQDGANQS 452 +V+ EQ A++ ++ +EA++ ++ Q AQ G+ Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV--------------AQSGSETK 1093 Query: 453 QQVDLAAKEGQQQQTQVVQDLLKLSQQLSSSHQAVEKVSQE-SEAISKVTEVINSIAEQT 511 + KE + + + Q + QE SE + E + Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE-----PARE 1148 Query: 512 NLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRTQSSI---LEISQTIDKLQSQVKTTT 568 N +N ++ + A+ T S++ + S T++ S V+ Sbjct: 1149 NDPTVNIKEPQSQTNTTA--------DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 569 SQMAQSHQLGIASANQGEETGKQLEEITRRIGELAISSRNIASATEQQSSVAQEITHNLH 628 + + Q + S + + + + + +++ +S+VA + + Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSV----PHNVEPATTSSNDRSTVALCDLTSTN 1256 Query: 629 QISELANEGEHRAAETVNSANDLS 652 + L++ +N +S Sbjct: 1257 TNAVLSDARAKAQFVALNVGKAVS 1280
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 380 bits (977), Expect = e-117 Identities = 208/1046 (19%), Positives = 431/1046 (41%), Gaps = 52/1046 (4%) Query: 1 MIKAFVENGRLVSLVIALLLVAGFGAMSSLPRTEDPHITNRFASVITPYPGASAERVEAL 60 M F+ ++ +L++AG A+ LP + P I SV YPGA A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTEVLENQLRRLEEIKLIQSTS-RPGISVIQLELKDTVTDTDPVWSR--ARDLLADARNT 117 VT+V+E + ++ + + STS G I L + TDP ++ ++ L A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS---GTDPDIAQVQVQNKLQLATPL 117 Query: 118 LPDGIQTPTL-DDQVGYAYTAILSLVWNDSSQPRVDMLNRYAKELQSRLRLLSGTDFVKL 176 LP +Q + ++ +Y + V ++ + D+ + A ++ L L+G V+L Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 177 YGAPEEEILVQLDGYKMSQLQLTPGTIAKILSSADSKIAAGEINN------NHFRALVEV 230 +GA + + + LD +++ +LTP + L + +IAAG++ A + Sbjct: 178 FGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 231 SGELDSQSRIRQVPLKVDAQGQIIRLGDIAHISRQPKTPADSIALVDGEQGVFVAARMLN 290 + +V L+V++ G ++RL D+A + + + IA ++G+ + ++ Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENY-NVIARINGKPAAGLGIKLAT 295 Query: 291 NTRVDIWQGQVKQLVDEFNQELPANIKVQWLFEQNSYTSERLGGLIVNLLQGFVIILAVL 350 +K + E P +KV + ++ + + ++ L + +++ V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 351 LLTLG-LRNAIIVALSLPLTALFTLACMKYIGLPIHQMSVTGLVVALGIMVDNAIVIVDA 409 L L +R +I +++P+ L T A + G I+ +++ G+V+A+G++VD+AIV+V+ Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 410 IAQRRQ-QGMSRLSAVSETLHHLWLPLAGSTITTILAFAPIVLMPGAAGEFVGGIAMSVM 468 + + + A +++ + L G + F P+ G+ G +++++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 469 FALLGSYVISHTLIAGLAGRF--SLEGKHP-------VWYQHGINVPLVSGYFQASLRFA 519 A+ S +++ L L + +H W+ + V+ Y S+ Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD-HSVNHY-TNSVGKI 533 Query: 520 LNRPLLSATFIGIIPLLGFYASGKMTEQFFPPSDRDMFQIELYLAPHVSLENTLNQV-QL 578 L +I ++ F P D+ +F + L + E T + Q+ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 579 MDKQLHQIEGIIQVDWVVGGNTPSFYYNLTQRQQGATNYAQAMVK-----ASDFERANAL 633 D L + ++ + V G ++ + + Q A A +K D A A+ Sbjct: 594 TDYYLKNEKANVESVFTVNG------FSFSGQAQNA-GMAFVSLKPWEERNGDENSAEAV 646 Query: 634 IPELQQTLDK---AFPEAQVLVRKLEQGPPFNAPVELM-IFGPNLETLRSLGDEVRNILA 689 I + L K F + +E G EL+ G + L +++ + A Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 690 ATP-DVLHTRATLSAGAPKVWLQVNEDASLISGLTLTDIARQVQMATTGVIGGSVLEQTE 748 P ++ R + L+V+++ + G++L+DI + + A G +++ Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGR 766 Query: 749 SLPIRVRLGDTSREQASRLSEIQLVTPSGTAVPLSALSHNEVQVSRGAIPRRNGQRVNTI 808 + V+ R + ++ + + +G VP SA + + + R NG I Sbjct: 767 VKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEI 826 Query: 809 EAYIVSGVLPAQVLNDVKAKVAAISLPAGYRIEIGGESAKRNEAVGNLLSNLILVVTLLL 868 + G + ++ A LPAG + G S + + + + + ++ Sbjct: 827 QGEAAPGTSSGDAMALMEN--LASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVF 884 Query: 869 ATVVLSFNSFRLTAIILLSALQSAGLGLLAVYVFGYPFGFPVIIALLGLMGLAINAAIVI 928 + + S+ + ++L LLA +F ++ LL +GL+ AI+I Sbjct: 885 LCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILI 944 Query: 929 LAELEDTDNARA-GDKEVIITTVSSCGRHISSTTITTVGGFIPLII---AGGGFWPPFAI 984 + +D G E + V R I T++ + G +PL I AG G I Sbjct: 945 VEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGI 1004 Query: 985 AIAGGTLLTTLLSLVWVPTMYLLLMK 1010 + GG + TLL++ +VP ++++ + Sbjct: 1005 GVMGGMVSATLLAIFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 5e-06 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 4/117 (3%) Query: 75 SGKLSELTVDSGAKVTQGQVLAKLDTRLLDAEHQEIQASLAQTQADVDLATSTLNRNLEL 134 + + E+ V G V +G VL KL +A+ + Q+SL Q + + L+R++EL Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ-TRYQILSRSIEL 162 Query: 135 KKSGYVSEQLLDENRTQLASLE-AAKKRLLASQRANQLKRDKSQLLAPFDGIISQRQ 190 K + L DE Q S E + L ++ + + K Q D ++R Sbjct: 163 NKLPELK--LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Score = 37.1 bits (86), Expect = 9e-05 Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 16/145 (11%) Query: 101 RLLDAEHQ--EIQASLAQTQADVDLATSTLNR---NLELKKSGYVSEQL--LDENRTQLA 153 +L+ E++ E L ++ ++ S + +L + +E L L + + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 154 SLEAAKKRLLASQRANQLKRDKSQLLAPFDGIISQRQ-HNLGEVVAAGSPVFTLVGSVNT 212 L N+ ++ S + AP + Q + H G VV + +V +T Sbjct: 313 LLTLEL-------AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 213 -EAYIGVPVAVAQQFVNGQNVTVSV 236 E V GQN + V Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKV 390
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.1 bits (179), Expect = 3e-18 Identities = 40/197 (20%), Positives = 68/197 (34%), Gaps = 5/197 (2%) Query: 11 RSEQKKQQVLVAAIDLFCRQGFPHTSMDEVAKQAGVSKQTVYSHYGSKDDLFVAAIE--S 68 +++ +Q +L A+ LF +QG TS+ E+AK AGV++ +Y H+ K DLF E Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 69 KCVGHNLNADLLSNPSQPEATLTEFALQFGEMIVSPEAITVFKACVAQSESHP---EVSR 125 +G P P + L E + E V+ E + + V + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 126 LFFEAGPQHMLAMLTKYLGAVEALGVYRFSQPHHCAVRLCLMLFGELKLRLELGLETESL 185 + + L + A + L ++ L Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDL 187 Query: 186 LGEREQYIRGCAEMFLK 202 E Y+ EM+L Sbjct: 188 KKEARDYVAILLEMYLL 204
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 32.6 bits (74), Expect = 0.007 Identities = 24/159 (15%), Positives = 56/159 (35%), Gaps = 11/159 (6%) Query: 418 EITLPPLEKSKLLSDSQFNTIKENDLNKAYFECKKIRNELIKLQY---LITEAKKLASKL 474 + P +E + + K DLN +E K Y L + S+ Sbjct: 623 NLREPNIEIDDISDSLLGLSFK--DLNNKLYEIYSKNIVYFKKIYFSFLDQWWTEYYSQY 680 Query: 475 NLDSKKSSSTLE-KIDKIELKINKKYKNLSQLIKFYGYFEFSKFLTT---REIESWTQPQ 530 + ++ + ++ + K+ +LS+ + + T ++ + +Q Sbjct: 681 FELICMAKQSILAQESLVKQIVQNKFTDLSKASIPPDTLKLIRETTEKTFIDLSNESQIS 740 Query: 531 INQMTERYYEAFLSSCVQVFKLVESACNKLQDRINELKT 569 +N++ +A S CV V + + ++ IN + Sbjct: 741 MNRVDNFLNKA--SICVFVEDIYPKFISYMEKYINNINI 777
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.6 bits (186), Expect = 1e-17 Identities = 41/231 (17%), Positives = 78/231 (33%), Gaps = 54/231 (23%) Query: 6 TILITGGTGSFGQKYTKTILERY-----------------KPKRLIIFSRDELKQYEMQQ 48 L+TG G G +K +LE K RL + ++ + ++ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 49 VFNAPCMRYFIGDVRDGDRLKQAFKDVDF--VIHAAALKQVPAAEYNPMECIKTNIHGAE 106 D+ D + + F F V + V + NP +N+ G Sbjct: 59 -----------IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFL 107 Query: 107 NVIRAAISNNVVKVIALST---------------DKAASPINLYGATKLASDKLFVAANN 151 N++ N + ++ S+ D P++LY ATK A++ + ++ Sbjct: 108 NILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 152 VVGDGKTRFAAVRYGNVVGSRGS---VVPFFKQLIANGATSLPITHPDMTR 199 + G +R+ V G G + F + + G + + M R Sbjct: 168 LYG---LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKR 215
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.4 bits (63), Expect = 0.034 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 88 VLKQGSYNNNEPYYLNNISARCPLKGNPGQQLHVDSALP 126 VLK+G Y N Y + N + PL+ + QL LP Sbjct: 166 VLKRGDYAVNVNYNVQNAGEK-PLEISSFGQLKQSITLP 203
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 26.6 bits (58), Expect = 0.041 Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 1/48 (2%) Query: 1 MKRYLFIVAALLLTGCAAK-DKYVQWEDVPPSSFPKLTAIGYAPLATQ 47 +K L + A LL C+ + D D P ++ L ++ Y LATQ Sbjct: 12 VKLLLMLGTAALLAACSNEADSLTTSIDAPVTASIDLQSVSYTDLATQ 59
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 3e-13 Identities = 25/128 (19%), Positives = 53/128 (41%), Gaps = 12/128 (9%) Query: 180 HIMVIDDSAVARKQIIRALESLNLQIDTAKDGREALDKLKAIAGEMNNVAEEIPLIISDI 239 I+V DD A R + +AL + + + A G+ L+++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD---------LVVTDV 55 Query: 240 EMPEMDGYTLTAEIRDDPKLKHIKVVLHTSLSGVFNQAMVQKVGANDFIAK-FNPDELAA 298 MP+ + + L I+ + V++ ++ + + GA D++ K F+ EL Sbjct: 56 VMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 299 AVNKHLSL 306 + + L+ Sbjct: 114 IIGRALAE 121
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 32.6 bits (74), Expect = 3e-04 Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 99 NVNVMEEMADMISASRSYQMNVQVAEAAKSMLQQTLGM 136 VN+ EE ++ + Y N QV + A ++ + + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 28.4 bits (63), Expect = 0.011 Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 8 DVAGSGMSAQSLRLNTTASNIANADSVSSSVDKTYRSRHPIFEAEMAKAQSQQQASQGVT 67 + A SG++A LNT ++NI++ + Y + I + + GV Sbjct: 5 NNAMSGLNAAQAALNTASNNISSYN------VAGYTRQTTIMAQANSTLGAGGWVGNGVY 58 Query: 68 VKGI 71 V G+ Sbjct: 59 VSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 40.3 bits (94), Expect = 1e-05 Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 2 SFNIALSGISAAQKDLNTTANNIANANTIGFKESR 36 N A+SG++AAQ LNT +NNI++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37 Score = 37.2 bits (86), Expect = 1e-04 Identities = 13/49 (26%), Positives = 25/49 (51%) Query: 405 SLSSSALEQSNIDLTTELVDLISAQRNFQANSRTLEVNNTLQQTVLQIR 453 LS+ S ++L E +L Q+ + AN++ L+ N + ++ IR Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.6 bits (105), Expect = 2e-07 Identities = 19/119 (15%), Positives = 41/119 (34%), Gaps = 4/119 (3%) Query: 145 EDATSITVSAEGEVSVKTPGAAENQVVGQLSMTDFINPSGLDPMGQNLYTETG---ASGT 201 D I +++E + + + Q + + +L ++ G A+ Sbjct: 427 TDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLK 486 Query: 202 PIQGTASLDGMGAIRQGALETSNVNVTEELVNLIESQRIYEMNSKVISAVDQMLAYVNQ 260 T + + S VN+ EE NL Q+ Y N++V+ + + + Sbjct: 487 TSSATQGNV-VTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 35.7 bits (82), Expect = 2e-04 Identities = 9/36 (25%), Positives = 20/36 (55%) Query: 5 LWISKTGLDAQQTDIAVISNNVANASTVGYKKSRAV 40 + + +GL+A Q + SNN+++ + GY + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI 39
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 147 bits (373), Expect = 2e-46 Identities = 75/215 (34%), Positives = 106/215 (49%), Gaps = 9/215 (4%) Query: 11 LLLAACSSTPKKPIADDPFYAPVYPEAPPTKIAATGSIYQDSQAA-----SLYSDIRAHK 65 L L C+ P P+ A P P A GSI+Q +Q L+ D R Sbjct: 17 LSLTGCAWIPSTPLVQGATSAQPVPGPTP---VANGSIFQSAQPINYGYQPLFEDRRPRN 73 Query: 66 VGDIITIVLKEATQAKKSAGNQIKKGSDMTLDPIYAGGSNVSL-GGIPLDLRYKDSMNTK 124 +GD +TIVL+E A KS+ + L G D+ Sbjct: 74 IGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFN 133 Query: 125 RESDADQSNSLDGSISANIMQVLNNGNLVVRGEKWISINNGDEFIRVTGIVRSQDIKPDN 184 + A+ SN+ G+++ + QVL NGNL V GEK I+IN G EFIR +G+V + I N Sbjct: 134 GKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSN 193 Query: 185 TIDSTRMANARIQYSGTGTFAEAQKVGWLSQFFMS 219 T+ ST++A+ARI+Y G G EAQ +GWL +FF++ Sbjct: 194 TVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLN 228
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 370 bits (952), Expect = e-130 Identities = 157/367 (42%), Positives = 222/367 (60%), Gaps = 14/367 (3%) Query: 5 LIVALAMLVLSLPSQAE--RIKDIANVQGVRSNQLIGYGLVVGLPGTGEK---TNYTEQT 59 L+ + + + P+QA+ RIKDIA++Q R NQLIGYGLVVGL GTG+ + +TEQ+ Sbjct: 11 LVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQS 70 Query: 60 FTTMLKNFGINLPDNFRPKIKNVAVVAVHADMPAFIKPGQQLDVTVSSLGEAKSLRGGTL 119 ML+N GI + KN+A V V A++P F PG ++DVTVSSLG+A SLRGG L Sbjct: 71 MRAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNL 129 Query: 120 LQTFLKGVDGNVYAIAQGSLVVSGFSAEGLDGSKVIQNTPTVGRIPNGAIVERSVATPFS 179 + T L G DG +YA+AQG+L+V+GFSA+G D + + Q T R+PNGAI+ER + + F Sbjct: 130 IMTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFK 188 Query: 180 SGDYLTFNLRRADFSTAQRMADAINDL----LGPDMARPLDATSVQVSAPRDVSQRVSFL 235 L LR DFSTA R+AD +N G +A P D+ + V PR V+ + Sbjct: 189 DSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLM 247 Query: 236 ATLENLDVIPAEESAKVIVNSRTGTIVVGQHVKLLPAAVTHGGLTVTIAEATQVSQPNAL 295 A +ENL + + AKV++N RTGTIV+G V++ AV++G LTV + E+ QV QP Sbjct: 248 AEIENL-TVETDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPF 306 Query: 296 ANGETVVTANTTIGVNESDRRMFMFSPGTTLDELVRAVNLVGAAPSDVLAILEALKVAGA 355 + G+T V T I + ++ G L LV +N +G ++AIL+ +K AGA Sbjct: 307 SRGQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGA 365 Query: 356 LHGELII 362 L EL++ Sbjct: 366 LQAELVL 372
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 149 bits (378), Expect = 2e-44 Identities = 67/160 (41%), Positives = 95/160 (59%), Gaps = 2/160 (1%) Query: 219 RETQKTLKFGSREEFLATLYPHAEKAAKALGTQPEVLLAQSALETGWGQKIVRGSNGAPS 278 R +L S+ FLA L A+ A++ G ++LAQ+ALE+GWGQ+ +R NG PS Sbjct: 139 RNYDDSLPGDSKA-FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPS 197 Query: 279 HNLFNIKADRRWLGDKANVSTLEFEQGIAVRQKADFRVYTDFEHSFNDFVTFIAEGERYQ 338 +NLF +KA W G ++T E+E G A + KA FRVY+ + + +D+V + RY Sbjct: 198 YNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYA 257 Query: 339 DAKKVAASPTQFIRALQDAGYATDPKYAEKVIKVMQTISQ 378 A AAS Q +ALQDAGYATDP YA K+ ++Q + Sbjct: 258 -AVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKS 296 Score = 87.8 bits (217), Expect = 1e-21 Identities = 39/93 (41%), Positives = 61/93 (65%), Gaps = 3/93 (3%) Query: 12 DLGGLDSLRAQAQKDEKGTLKQVAQQFEGIFVQMLMKSMRDANAVFESDSPLNSQYTKFY 71 D L+ L+A+A +D ++ VA+Q EG+FVQM++KSMRDA D +S++T+ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALP---KDGLFSSEHTRLY 70 Query: 72 EQMRDQQLSVDLSDKGVLGLADMMVQQLSPESS 104 M DQQ++ ++ LGLA+MMV+Q++PE Sbjct: 71 TSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQP 103
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 219 bits (560), Expect = 6e-66 Identities = 127/460 (27%), Positives = 193/460 (41%), Gaps = 29/460 (6%) Query: 4 DLLNIARTGVLASQSQLGVTSNNIANANTAGYHRQVATQSTLESQRLGNSFYGTGTYVDD 63 L+N A +G+ A+Q+ L SNNI++ N AGY RQ + S + G G YV Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 64 VKRIYNDYAARELRIGQTTLSGAEASYGKLSELDQLFSQIGKMVPQSLNSLFTGLNSLAD 123 V+R Y+ + +LR QT SG A Y ++S++D + S + + FT L +L Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 124 LPADLGIRSSTLNDAKQLANSLNQMQSSLNGQMTQTNDQITGMTKRINEISKELANLNLE 183 D R + + ++ L N L Q Q N I +IN +K++A+LN + Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 184 LMKSPNQDAM-----LLDKQDALIQELSQYAQVNVIPQENGAKSIMLGGSVMLVSGEIAM 238 + + A LLD++D L+ EL+Q V V Q+ G +I + LV G A Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 239 TMDTKTGDPFPNELQLTSSIGSQSVAADPSKL--GGQLGALFEYRDQTLIPASHELDQLA 296 + P+ + G+ P KL G LG + +R Q L + L QLA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LGIADNFNKMQAQGFDLNGQVGSNIFRDINDPLMSLGRVGGYSNNTGNATLGVNIDDTRL 356 L A+ FN GFD NG G + F + V + N G+ +G + D Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA------IGKPAVLQNTKNKGDVAIGATVTDASA 355 Query: 357 LTGGSYELSF-------TAPASYELRDTETGVITPLTLNGSTLEGGAGFSIDIKAGAMAS 409 + Y++SF T AS + +G L G A Sbjct: 356 VLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFT---------GTPAV 406 Query: 410 GDRFVIRPTAGAANGITVEMTDPKGIAAASPKITADAANS 449 D F ++P + A + V +TD IA AS + D+ N Sbjct: 407 NDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNR 446 Score = 89.6 bits (222), Expect = 8e-21 Identities = 38/103 (36%), Positives = 55/103 (53%) Query: 535 AEGDNSNAVAMAKLSESKVMNGGKSTLADVFENTKIDIGSKTKAAEVRVGSAEAIYQQAY 594 + DN N A+ L + GG + D + + DIG+KT + + + Q Sbjct: 441 GDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLS 500 Query: 595 ARVESESGVNLDEEAANLMRFQQAYQASARIMTTAQQIFDTLL 637 + +S SGVNLDEE NL RFQQ Y A+A+++ TA IFD L+ Sbjct: 501 NQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALI 543
>FLAGELLIN#Flagellin signature. Length = 507 Score = 58.1 bits (140), Expect = 2e-11 Identities = 63/359 (17%), Positives = 119/359 (33%), Gaps = 8/359 (2%) Query: 20 QTATSKILEQLSSGKKVNTAGDDPVAALGIDNLNQRNALVDQFMKNIDYATNRLAVTESK 79 Q++ S +E+LSSG ++N+A DD + + Q +N + + TE Sbjct: 21 QSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGA 80 Query: 80 LGSAENLASSIREQVMRAVNGTLADSERQMIADEMKGSLEELLSIANSKDESGNYMFSGY 139 L N +RE ++A NGT +DS+ + I DE++ LEE+ ++N +G + S Sbjct: 81 LNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVLSQ- 139 Query: 140 STDKEPFAFDNSTPPKIVYSGDSGIRNSLVQSGVALGTNVPGDTAFMKAPNGLGDYSVNY 199 + N + ++ V+S G NV G +V Sbjct: 140 DNQMKIQVGANDGETITID-----LQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTG 194 Query: 200 LASQQGEFSVKTAKIADPATYLADTYTFNFSDNGSGGTNLQVLDSANNPVANIANFDAAT 259 + + + A T N Q+ + F Sbjct: 195 YDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTK 254 Query: 260 PVSFNGIEVNISGKPSAGDSFTMEPQSEVSIFDTISRAIALIEDPNSANTPQGRSQLAQI 319 + I+G G V+ TI + + T G + Sbjct: 255 STAGTAEAKAIAGAIKGGKEGDTFDYKGVTF--TIDTKTGNDGNGKVSTTINGEKVTLTV 312 Query: 320 LNDIDSGVNQISSARSVAGNNLKAVESYKDTHIEEQVLNTSALSLLEDLDYASAITEFA 378 + N ++ + N +V + + T ++ ++ LS LE + ++ Sbjct: 313 ADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKIT 371
>FLAGELLIN#Flagellin signature. Length = 507 Score = 134 bits (337), Expect = 4e-38 Identities = 93/271 (34%), Positives = 125/271 (46%), Gaps = 10/271 (3%) Query: 2 AITVNTNVTSMKAQKNLNTSSSGLATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN S+ Q NLN S S L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTVQAENGANSTDDLDAIQKEINQLSE 121 RNAND ISIAQ EGA+ E N LQR+R+L+VQA NG NS DL +IQ EI Q E Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITAIGDSTAFGNTLLMTGLFSTGKTFQVGHQEGEDITISVGTTNAGSL--------SVN 173 EI + + T F +++ QVG +GE ITI + + SL Sbjct: 121 EIDRVSNQTQFNGVKVLSQ--DNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPK 178 Query: 174 ALAIASAGGRSTALANIDAAIKTIDNQRANLGAKQNRLAYNISNSANTQANVADAKSRIV 233 + + D + R ++ + + A Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 234 DVDFAKETSVMTKNQVLQQTGSAMLAQANQL 264 D + K + A A + Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 85.9 bits (212), Expect = 4e-21 Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 4/213 (1%) Query: 60 GLDVGMRNANDAISIAQIAEGAMQEQTNMLQRMRDLTVQAENGANSTDDLDAIQKEINQL 119 + + +++A I GA LQ +++ NG + DD + Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 120 SEEITAIGDSTAFGNTLLMTGLFSTGKTFQVGHQEGEDITISVGTTNAGSLSVNALAIAS 179 E A+ + + G + + T + S +N A A+ Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGK----TMFIDKTASGVSTLINEDAAAA 413 Query: 180 AGGRSTALANIDAAIKTIDNQRANLGAKQNRLAYNISNSANTQANVADAKSRIVDVDFAK 239 + LA+ID+A+ +D R++LGA QNR I+N NT N+ A+SRI D D+A Sbjct: 414 KKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYAT 473 Query: 240 ETSVMTKNQVLQQTGSAMLAQANQLPQVALSLL 272 E S M+K Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 474 EVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>FLAGELLIN#Flagellin signature. Length = 507 Score = 139 bits (350), Expect = 5e-40 Identities = 98/270 (36%), Positives = 129/270 (47%), Gaps = 10/270 (3%) Query: 2 AITVNTNVTSLKAQKNLNTSASGLATSMERLSSGLRINSAKDDAAGLAISNRLNSQVRGL 61 A +NTN SL Q NLN S S L++++ERLSSGLRINSAKDDAAG AI+NR S ++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 EVGMRNANDAISIAQISEGAMQEQTNMLQRMRDLTVQSENGANSTDDLDAIQKEIDQLAL 121 RNAND ISIAQ +EGA+ E N LQR+R+L+VQ+ NG NS DL +IQ EI Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITEIGDNTAFGSTKLLDGTFSGKTFQVGHQSGEDITISVAKTTASALKVDSLDITGSAR 181 EI + + T F K+L QVG GE ITI + K +L +D ++ G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 ASALAA---------IDAAIKTIDSQRADLGAKQNRLAYNISNSANTQANIADAKSRIVD 232 A+ D + R D+ + + A D Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 233 VDFAKETSQMTKNQVLQQTGSAMLAQANQL 262 + K + A A + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAI 269 Score = 84.3 bits (208), Expect = 1e-20 Identities = 63/212 (29%), Positives = 101/212 (47%), Gaps = 4/212 (1%) Query: 60 GLEVGMRNANDAISIAQISEGAMQEQTNMLQRMRDLTVQSENGANSTDDLDAIQKEIDQ- 118 + + +++A I+ GA LQ +++ NG + DD + Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 119 LALEITEIGDNTAFGSTKLLDGTFSGKTFQVGHQSGEDITISVAKTTASALKVDSLDITG 178 L G++ + +G + ++ I + S L + Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTM---FIDKTASGVSTLINEDAAAAK 414 Query: 179 SARASALAAIDAAIKTIDSQRADLGAKQNRLAYNISNSANTQANIADAKSRIVDVDFAKE 238 + A+ LA+ID+A+ +D+ R+ LGA QNR I+N NT N+ A+SRI D D+A E Sbjct: 415 KSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATE 474 Query: 239 TSQMTKNQVLQQTGSAMLAQANQLPQVALSLL 270 S M+K Q+LQQ G+++LAQANQ+PQ LSLL Sbjct: 475 VSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 52.5 bits (126), Expect = 2e-11 Identities = 17/87 (19%), Positives = 30/87 (34%), Gaps = 3/87 (3%) Query: 8 TQQAVALSYDGKN--APKVVASGEGLVADEIIALAKASGVFIHQDPHLSNFL-RLLELGE 64 T A+ + Y P V + +A+ GV I Q L+ L + Sbjct: 265 THIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDH 324 Query: 65 EIPKELYLLIAELIAFVYMLDGKFPEQ 91 IP E AE++ ++ + + Sbjct: 325 YIPAEQIEATAEVLRWLERQNIEKQHS 351
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 229 bits (584), Expect = 2e-77 Identities = 87/222 (39%), Positives = 126/222 (56%), Gaps = 4/222 (1%) Query: 44 PRDPFEGFNRAMWDFNYLYLDRYIYRPVAHGYNDYLPLPAKTGINNFVQNLEEPSSLVNN 103 DP EGFNR M++FN+ LD YI RPVA + DY+P PA+ G++NF NLEEP+ +VN Sbjct: 28 RSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNY 87 Query: 104 ALQGKWGWAANAGGRFTVNTTIGLLGVFDVADMMGMPRKQDE---FNEVLGYYGVPNGPY 160 LQG RF +NT +G+ G DVA M ++ E F LG+YGV GPY Sbjct: 88 FLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPY 147 Query: 161 FMAPFAGPYVVRELASDWVDGLYFPLSELTVWQSIVKWGLKSLHARASAIDQERLVDNAL 220 PF G + +R+ D D LY LS LT S+ KW L+ + RA +D + L+ + Sbjct: 148 VQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSS 207 Query: 221 DPYTFVKDAYLQHMDYKVYDGNV-PQKQEDDELLDQYMQELE 261 DPY V++AY Q D+ G + PQ+ + + + +++++ Sbjct: 208 DPYIMVREAYFQRHDFIANGGELKPQENPNAQAIQDDLKDID 249
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.6 bits (217), Expect = 4e-21 Identities = 28/101 (27%), Positives = 44/101 (43%) Query: 7 SILWVEDDPVFRQIVATFLIGRGAKVVQACDGEQGLYIFKQQRFDIILADLSMPKLGGLD 66 +IL +DD R ++ L G V + D+++ D+ MP D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 MLKEMSKLEPLVPSIVVSGNNVMADVVEALRVGACDYLVKP 107 +L + K P +P +V+S N ++A GA DYL KP Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 175 bits (445), Expect = 4e-54 Identities = 83/361 (22%), Positives = 149/361 (41%), Gaps = 51/361 (14%) Query: 1 MKILVTGGAGFIGSAVIRHIIMNTNDSVINVDKLT--YAGNLESLKL-VSTNPRYNFEQV 57 MK LVTG AGFIG V + ++ + V+ +D L Y +L+ +L + P + F ++ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDRATLERVFSQYQPDAVMHLAAESHVDRSITGPSDFIQTNIVGTYILLEAARQYWTQ 117 D+ DR + +F+ + V V S+ P + +N+ G +LE R Q Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 LDAERKAAFRFHHISTDEVYGDLPHPDEQEGQAVNQYLPLFTETTPYAPSSPYSASKASS 177 + S+ VYG N+ +P T+ + P S Y+A+K ++ Sbjct: 120 ---------HLLYASSSSVYGL------------NRKMPFSTDDSVDHPVSLYAATKKAN 158 Query: 178 DHLVRAWLRTYGFPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKSLPIYGKGDQIRDWL 237 + + + YG P YGP+ P+ + LEGKS+ +Y G RD+ Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218 Query: 238 YVEDHARALYKVV------------------TEGKVGETYNIGGHNEKQNIEVVKTICSI 279 Y++D A A+ ++ YNIG +E++ I ++ Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS---SPVELMDYIQAL 275 Query: 280 LDSLVPKATPYAEQITFVTDRPGHDRRYAIDASKMSAELNWQPQETFETGLRKTIEWYLA 339 D+L +A + + +PG + D + + + P+ T + G++ + WY Sbjct: 276 EDALGIEA-----KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 340 N 340 Sbjct: 331 F 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.2 bits (120), Expect = 3e-09 Identities = 32/161 (19%), Positives = 58/161 (36%), Gaps = 27/161 (16%) Query: 1 MKILVTGSNGQVGSCLVKLLNQIPEIEFLAVD--------------REQL---------- 36 MK LVTG+ G +G + K L + + + +D E L Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 37 DITDYEAVNKLVSEFKPDAIINAAAHTAVDKAEQEVELSYAINRDGPQFLAQAANSVG-A 95 D+ D E + L + + + + AV + + N G + + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 96 TILHISTDYVFAGDKVGEYVETDEVA-PQGIYGKSKLAGEL 135 +L+ S+ V+ ++ + D V P +Y +K A EL Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL 160
>PF06291#Lambda prophage Bor protein Length = 102 Score = 29.6 bits (66), Expect = 0.002 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 19 MKLSQISLALLALMITACSEPAKTVANEPVAAPHQDTQTN 58 MK S AL A++IT C++ TV N+P A ++T T+ Sbjct: 6 MKKMLFSAAL-AMLITGCAQQTFTVGNKPTAVTPKETITH 44
>PF06580#Sensor histidine kinase Length = 349 Score = 46.8 bits (111), Expect = 8e-08 Identities = 36/197 (18%), Positives = 75/197 (38%), Gaps = 36/197 (18%) Query: 266 NTMQDGLGLIERNLSRAAELV--------HNFKRTAADQSVLERERFNLKTYIFQIFSSL 317 N + + LI + ++A E++ ++ + + A Q L E + +Y+ + S Sbjct: 177 NALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQ-LAS-- 233 Query: 318 RPLMR-KKNIVLNVELDDDIFIESYPGAIAQIFTNLVANSFRHGFPESFTGDKSITIRVQ 376 ++ + + +++ I P + Q LV N +HG + G K I ++ Sbjct: 234 ---IQFEDRLQFENQINPAIMDVQVPPMLVQT---LVENGIKHGIAQLPQGGK-ILLKGT 286 Query: 377 KQDSNICMQYQDNGVGMSDEVKLKAFEPFFTTARKDGGTGLGMSIIYNLVTQKLHGTI-- 434 K + + ++ ++ G K TG G+ + + Q L+GT Sbjct: 287 KDNGTVTLEVENTGSLALKNTK--------------ESTGTGLQNVRERL-QMLYGTEAQ 331 Query: 435 LLASSPDQGVKVEIQIP 451 + S V + IP Sbjct: 332 IKLSEKQGKVNAMVLIP 348
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 79.9 bits (197), Expect = 2e-18 Identities = 32/165 (19%), Positives = 81/165 (49%), Gaps = 4/165 (2%) Query: 434 VSIVEERTIGPSLGAENIESGVQAMIWGMAVVLIFMLVYYR-SFGLIANLALTANLVMVV 492 + I ++GP + E + + V +++ V++ ++ V + F L A +AL ++++ V Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 493 GVMSMIPGAVLTLPGIAGMVLTVGMAVDGNVLIYERIREELRA--GRSVQQAIHEGYGNA 550 G+ +++ L +A ++ G +++ V++++R+RE L ++ ++ Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 551 FSTIADANITTFLTALILFAVGTGAIKGFAVTLMIGIATSMFTAI 595 S +TT L + + G I+GF ++ G+ T ++++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSV 298
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 314 bits (807), Expect = e-109 Identities = 111/309 (35%), Positives = 178/309 (57%), Gaps = 14/309 (4%) Query: 2 LEILSLKRTVNFLRHALPISIMSAILVFGSLVSLATKGINWGLDFTGGTVVEMEFTQPVD 61 L+++ K +F R + +++ S++ G+N+G+DF GGT + E T +D Sbjct: 5 LKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAID 64 Query: 62 LNVLRTKLSAPELDGAVVQNFGSSR------DVLVRLSVKE--------GVSSDVQVKSV 107 + V R L EL ++ ++R+ ++E G V V Sbjct: 65 VGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKV 124 Query: 108 MAAAQQVDAGVQQKRVEFVGPQVGKELAEQGGLAVLVALICIMIYVSFRFEWRLAFGSVA 167 A VD ++ E VGP+V EL ++L A + IM Y+ RFEW+ A G+V Sbjct: 125 ETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVV 184 Query: 168 ALAHDVIVTLGVFSVFQLEFDLTVLAGVLTVVGYSLNDTIVVFDRIRENFLKMRKSEPEE 227 AL HDV++T+G+F+V QL+FDLT +A +LT+ GYS+NDT+VVFDR+REN +K + + Sbjct: 185 ALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRD 244 Query: 228 VVNVSITQTMSRTIITTGTTLVTVVALFLKGGTMIHGFATALLLGIFVGTYSSIYVASYL 287 V+N+S+ +T+SRT++T TTL+ +V + + GG +I GF A++ G+F GTYSS+YVA + Sbjct: 245 VMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNI 304 Query: 288 AIKLGICRE 296 + +G+ R Sbjct: 305 VLFIGLDRN 313
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 57.4 bits (138), Expect = 2e-10 Identities = 46/269 (17%), Positives = 96/269 (35%), Gaps = 22/269 (8%) Query: 406 NGLYNQGNALMQLGKPDKAKERYQAALDKQPDFPQAKANLELAEKLLNQ----------- 454 NG Y+ N ++ + Q D P +N E ++ Sbjct: 975 NGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS 1034 Query: 455 QQSQQNADNQEKQSQGDENQQGQNQNDQQQGQNQQQGQQGDQQSSQNDQAQDQSQEQQSQ 514 + ++ A+N +++S+ E + + QN++ ++ N Q + +Q Sbjct: 1035 ETTETVAENSKQESKTVEKN--EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 515 QQNNPDQADEKPSQEQESSSEQSNLEQGAQDKQQASDDKAKQDQQDAQQEQQQAEQQANQ 574 ++ + E + E+E + + E+ + + S KQ+Q + Q Q + + Sbjct: 1093 KETQTTETKETATVEKEEKA-KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA----R 1147 Query: 575 QNRADNNAEDKEEQASNEAKMQAQVEDDKSKAEQEQQQAVAQKADKEKQSQADKNPDTAI 634 +N N ++ + Q + A + ++ S EQ V + + +NP+ Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQP----VTESTTVNTGNSVVENPENTT 1203 Query: 635 ESVEAPPSNSEPLPAEMQRALRGVSEDPQ 663 + P NSE R R V P Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Score = 54.7 bits (131), Expect = 1e-09 Identities = 35/189 (18%), Positives = 70/189 (37%), Gaps = 3/189 (1%) Query: 495 DQQSSQNDQAQDQSQEQQSQQQNNPDQADEKPSQEQESSSEQSNLEQGAQDKQQASDDKA 554 + Q+ + + + + P A PS+ E+ +E S E +K + + Sbjct: 1002 NIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATET 1061 Query: 555 KQDQQDAQQEQQQAEQQANQQNRADNNAEDKEEQASNEAKMQAQVE-DDKSKAEQEQQQA 613 ++ +E + + Q N + + +E + E K A VE ++K+K E E+ Q Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 614 VAQKADKE--KQSQADKNPDTAIESVEAPPSNSEPLPAEMQRALRGVSEDPQVLLRNKMQ 671 V + + KQ Q++ A + E P+ + P + + N Q Sbjct: 1122 VPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQ 1181 Query: 672 LEYQKRRQN 680 + N Sbjct: 1182 PVTESTTVN 1190 Score = 34.3 bits (78), Expect = 0.002 Identities = 38/269 (14%), Positives = 79/269 (29%), Gaps = 20/269 (7%) Query: 360 AMQAYQAEDYANAAQKFETPQWQGAAQYKAGEYEQALKNFEQDSSANGLYNQGNALMQLG 419 + + + K Q A + A E A + + AN Q N + Q G Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAK-SNVKAN---TQTNEVAQSG 1089 Query: 420 KPDKAKERYQAALDKQPDFPQAKANLELAEKLLNQQQSQQNADNQEKQSQGDENQQGQNQ 479 K + + + KA +E + + + Q + QE+ + + Sbjct: 1090 SETKETQT-TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Query: 480 NDQQQGQNQQQGQQGDQQSSQN-----------DQAQDQSQEQQSQQQNNPDQADE---K 525 ND + Q Q ++ + + + NP+ + Sbjct: 1149 NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Query: 526 PSQEQESSSEQSNLEQGAQDKQQASDDKAKQDQQDAQQEQQQAEQQANQQNRADNNAEDK 585 P+ ESS++ N + + + + A D + + N ++A K Sbjct: 1209 PTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV-ALCDLTSTNTNAVLSDARAK 1267 Query: 586 EEQASNEAKMQAQVEDDKSKAEQEQQQAV 614 + + + + E Q V Sbjct: 1268 AQFVALNVGKAVSQHISQLEMNNEGQYNV 1296
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 8e-04 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 19/139 (13%) Query: 28 LIALIANG--HLLVEGPPGLAKT---RAVKALCDGVEGDFHRIQ---FTPDLLPADLTG- 78 ++A + L++ G G K RA+ G F I DL+ ++L G Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH 211 Query: 79 -----TDIYRSQTGTFEFEAGPIFHNLILADEINRAPAKVQSALLEAMAEGQVT-VGKNS 132 T TG FE G + DEI P Q+ LL + +G+ T VG + Sbjct: 212 EKGAFTGAQTRSTGRFEQAEG----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 133 YKLPPLFLVMATQNPLENE 151 + +V AT L+ Sbjct: 268 PIRSDVRIVAATNKDLKQS 286
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 2e-19 Identities = 30/144 (20%), Positives = 59/144 (40%), Gaps = 6/144 (4%) Query: 2 ISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMG 61 +I + DD +RT + + L G V + + T +W + D+++ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRITS-NAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVL----QAIRQ 117 + +I + +P ++V++ K + GA YL K E++ +A+ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 118 VSRGQRYLSPEIAQQMALSQFNPA 141 R L + M L + A Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAA 145
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 119 bits (299), Expect = 1e-31 Identities = 60/247 (24%), Positives = 102/247 (41%), Gaps = 50/247 (20%) Query: 251 FVYNEQTKLNDPTEYKICINGHGLSVASSIAAIQNNGKGIASAVGSENIDIVPVKVIDSC 310 F +++ +Y NGHG VA +IAA +N + A ++ ++ +KV++ Sbjct: 69 FTDDDEGDPEIFKDY----NGHGTHVAGTIAATENENGVVGVAPEAD---LLIIKVLNKQ 121 Query: 311 TGSALTSDLIKAIYWAAKSDDTFEGLEPISEPVDVINLSLGSNKNELCEVGYNAFADAVD 370 GS +I+ IY+A + VD+I++SLG + +AV Sbjct: 122 -GSGQYDWIIQGIYYAIEQK------------VDIISMSLGGPE------DVPELHEAVK 162 Query: 371 YAKQKGIVVVAALGNDGVSGD----IFTPATCNGVIPVSSNNVHGQLSYFSSYLSDKRTL 426 A I+V+ A GN+G D + P N VI V + N S FS+ ++ L Sbjct: 163 KAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEV-DL 221 Query: 427 STIGEDMTLPKVTTTTYIDRNFIDTNCQGSIESCYATGQGTSYSAPIVSGLVSMVLMQNP 486 GED+ +T YAT GTS + P V+G ++++ Sbjct: 222 VAPGEDI------LSTVPG-------------GKYATFSGTSMATPHVAGALALIKQLAN 262 Query: 487 SLNPDEI 493 + ++ Sbjct: 263 ASFERDL 269
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 92.1 bits (229), Expect = 2e-28 Identities = 35/88 (39%), Positives = 52/88 (59%) Query: 2 NKAQLIQRIATSLEQSQASTRPVVEQILQQIHIALSEGEKVFLPQFGTFELRYHLPKSGR 61 NK LI ++A + E ++ + V+ + + L++GEKV L FG FE+R + GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGETMEIAGFNQPSFKAATALKQAI 89 NPQTGE ++I P+FKA ALK A+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.6 bits (76), Expect = 0.005 Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 1/50 (2%) Query: 182 QVLDGIIHSHANQVLHRDIKPDNILVDD-DGRVHVIDFGISKLMGEQGNG 230 ++LD H V+H DIKP N++ D G VID G+ GEQ G Sbjct: 253 RLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKG 302
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 664 bits (1715), Expect = 0.0 Identities = 262/1091 (24%), Positives = 470/1091 (43%), Gaps = 94/1091 (8%) Query: 7 SVKRPVTVWMFMLAIMLFGMVGFSRLAVKLLPDLSYPTLTIRTMYDGAAPVEVEQLVSKP 66 ++RP+ W+ + +M+ G + +L V P ++ P +++ Y GA V+ V++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 IEEAVGVVKGLRKISSISRS-GMSDVVLEFEWGTTMDMASLDVREKLDTI--ALPLDVKK 123 IE+ + + L +SS S S G + L F+ GT D+A + V+ KL LP +V++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 124 PLLLRFNPNLDPIMRLALSVPNASEAELKQMRTYAEEELKRRLEALSGVAAVRLSGGLEQ 183 + + +M N + Y +K L L+GV V+L G + Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGT-TQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QY 182 Query: 184 EVHIQLNQEKLSQLNLNADDIKRRINEENINLSAGKVIQGD------REYLVRTLNQFNS 237 + I L+ + L++ L D+ ++ +N ++AG++ + +F + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 LEELGQVIVYRDAQ-TLVRLFEVATITDAFKERSDITRIGSQESIELAIYKEGDANTVAV 296 EE G+V + ++ ++VRL +VA + + + I RI + + L I AN + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 AKKLRDELVKINQD-PKQNKLEVIYDQSEFIESAVSEVTSSALMGSILSMLVIYLFLRNI 355 AK ++ +L ++ P+ K+ YD + F++ ++ EV + +L LV+YLFL+N+ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 356 IPTLIISISIPFSVIATFNMMYFADISLNIMSLGGIALAIGLLVDNAIVVLENIDRC-RS 414 TLI +I++P ++ TF ++ S+N +++ G+ LAIGLLVD+AIVV+EN++R Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 415 EGMSKLDAAVTGTKEVAGAIFASTLTTLAVFVPLVFVDGIAGALFSDQALTVTFALLASL 474 + + +A ++ GA+ + AVF+P+ F G GA++ ++T+ A+ S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 475 LVALTSIPMLASREGFTALPELIKKTPKEKPTTKLGKLKHYSATVFSFPIVLLFSYLPSA 534 LVAL P L + L+K E K Sbjct: 483 LVALILTPALCAT--------LLKPVSAEHHENK-------------------------- 508 Query: 535 LLTLALVIGRFFSWLLGLVMRPLSSGFNFVYHAIESVYHKLLAMALRKQVATLLLTIGIT 594 G FF W FN + + Y + L LL+ I Sbjct: 509 --------GGFFGW------------FNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIV 548 Query: 595 GACISLLPRLGMELIPPMNQGEFYVEILLPPGTAVGETDKVLQQLAMSI--KDRPEVKHA 652 + L RL +P +QG F I LP G T KVL Q+ ++ V+ Sbjct: 549 AGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESV 608 Query: 653 YSQAGSGGLMTSDTARGGENWGRLQVVLNDHTAYHQVTQVLRDTARRIPELEAKIEQPEL 712 ++ G + +N G V L + R KI + Sbjct: 609 FTVNGFS------FSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 713 FSFKTPLEIEL---TGYDLHLLKRSADNLVKALSASERFA-----------DVNTSLRDG 758 F P +EL TG+D L+ ++ A + V + + Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 759 QPELSIRFDHARLAALGMDAPTVANRIAQRVGGTVASQYTVRDRKIDILVRSELNERDQI 818 + + D + ALG+ + I+ +GGT + + R R + V+++ R Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 819 SDIDALIINPNSPQPIALSAVAEVSLQLGPSAINRISQQRVALVSANLAYG-DLSDAVAE 877 D+D L + + + + SA G + R + + A G DA+A Sbjct: 783 EDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMAL 842 Query: 878 AQQILSAQVLPASVQARFGGQNEEMEHSFQSLKIALILAVFLVYLVMASQFESLLHPLLI 937 + + S LPA + + G + + S + ++ +V+L +A+ +ES P+ + Sbjct: 843 MENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 938 LFAVPMALAGSVLGLYITQTHLSVVVFIGLIMLAGIVVNNAIVLVDRINQL-RTEGVDKL 996 + VP+ + G +L + V +GL+ G+ NAI++V+ L EG + Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 997 EAIKVAAKSRLRPIMMTTLTTTLGLLPMALGLGDGSEVRAPMAITVIFGLSLSTLLTLIV 1056 EA +A + RLRPI+MT+L LG+LP+A+ G GS + + I V+ G+ +TLL + Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1057 IPVLYALFDRK 1067 +PV + + R Sbjct: 1021 VPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.2 bits (107), Expect = 3e-07 Identities = 38/202 (18%), Positives = 79/202 (39%), Gaps = 24/202 (11%) Query: 91 LAVIDAKRQ----QYDLDRSEAEVKIIEQELNRLK---KMTNKEFIS--ADSMAKLEYNL 141 AV++ + + +L +++++ IE E+ K ++ + F + D + + N+ Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Query: 142 QAAIARRDLAELQVKESHVVSPIDGIVAKRYVKA-GNMAQEFGDLFYIV-NQDELHGIVH 199 E + + S + +P+ V + V G + L IV D L Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL 371 Query: 200 LPEQQLTSLRLGQEAQV-FS--NQQSKNAIHAKVLRISP--VVDPQSGT-FKVTLAVP-- 251 + + + + +GQ A + + KV I+ + D + G F V +++ Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEEN 431 Query: 252 -----NQNAHLKAGMFTRVELK 268 N+N L +GM E+K Sbjct: 432 CLSTGNKNIPLSSGMAVTAEIK 453 Score = 40.2 bits (94), Expect = 9e-06 Identities = 12/49 (24%), Positives = 26/49 (53%) Query: 72 GLIEAINVEEGDRVQKGQILAVIDAKRQQYDLDRSEAEVKIIEQELNRL 120 +++ I V+EG+ V+KG +L + A + D ++++ + E R Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRY 153
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 21/101 (20%), Positives = 34/101 (33%), Gaps = 23/101 (22%) Query: 356 LMENAFRLCISQ------VQVSARYTDQGDFELIVEDDGPGVEEKLRQKIIQRGVRADTQ 409 L+EN + I+Q + + D G L VE+ G + ++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTK-DNGTVTLEVENTGSLALKNTKE------------ 309 Query: 410 SPGQGIGLA-VCDEIVSSYGGELSIE-ESHLEGARFRIRIP 448 G GL V + + YG E I+ + IP Sbjct: 310 --STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 2e-18 Identities = 31/120 (25%), Positives = 57/120 (47%), Gaps = 1/120 (0%) Query: 5 RILVVEDDLILSHHLKVQLSDLGNQVQVALTAKEGFFQATNYPIDVAIVDLGLPDQDGIS 64 ILV +DD + L LS G V++ A + D+ + D+ +PD++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 65 LIQQLREEGVKAPILILTARVNWQDKVEGLNAGADDYLVKPFQKEELVARLD-ALVRRSA 123 L+ ++++ P+L+++A+ + ++ GA DYL KPF EL+ + AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>INTIMIN#Intimin signature. Length = 939 Score = 61.2 bits (148), Expect = 2e-11 Identities = 50/212 (23%), Positives = 86/212 (40%), Gaps = 24/212 (11%) Query: 249 VVVKPIDAYSIALTITDSQGQELRNISHSV-PGSVIATLRKDGVPTSYQTISFNLTGQGT 307 + V + +TD + + + AT++K+GV + +SFN+ GT Sbjct: 546 ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIV-SGT 604 Query: 308 LNPSSGTALTDLNGHASVTLVTGTNAGAGTVTASFSLENETITDSFNFEVAGDAPGGNGE 367 S+ +A T+ +G A+VTL + G V+A + A N Sbjct: 605 AVLSANSANTNGSGKATVTLKSDK-PGQVVVSA---------------KTAEMTSALNAN 648 Query: 368 ANSLSIQLTNSQTGVPTTDISATQPGKVTVAL---VDKDSTPLVGKVVSFSSTLGNFLPT 424 A Q S T + +A G+ + V K P+ + V+F++TLG + Sbjct: 649 AVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGK--LS 706 Query: 425 QGTALTDSLGRASITLTAGSIEGAGEITATYG 456 T TD+ G A +TLT+ + G ++A Sbjct: 707 NSTEKTDTNGYAKVTLTSTTP-GKSLVSARVS 737 Score = 36.6 bits (84), Expect = 7e-04 Identities = 46/207 (22%), Positives = 81/207 (39%), Gaps = 16/207 (7%) Query: 32 GTTPQPSVVTVTLSISNSDNVSLDTPAEVQATVVDSKTGPKAGIVVTFKLDNDELGTFTP 91 G VT + S ATV + +A + V+F + + GT Sbjct: 552 GQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGV-AQANVPVSFNIVS---GTAVL 607 Query: 92 STGTQLTDSSGVAKIKLETRNLAGAGSVTASIVTGESASIGFYSKGDGAINPGTGNKLKL 151 S + T+ SG A + L++ +V+ ++A + + I Sbjct: 608 SANSANTNGSGKATVTLKS------DKPGQVVVSAKTAEMTSALNANAVIFVDQTKASIT 661 Query: 152 FLVNAQGQAITSISTATPGVVKALYTNSSDEPLVGKVITFTSTLGKFQPESGTALTDTQG 211 + + A+ + A VK + D+P+ + +TFT+TLGK + T TDT G Sbjct: 662 EIKADKTTAVANGQDAITYTVKVMK---GDKPVSNQEVTFTTTLGK--LSNSTEKTDTNG 716 Query: 212 LAKIAITAGTVAGAGKIIAKADDTESE 238 AK+ +T+ T G + A+ D + Sbjct: 717 YAKVTLTSTTP-GKSLVSARVSDVAVD 742 Score = 36.2 bits (83), Expect = 0.001 Identities = 64/300 (21%), Positives = 104/300 (34%), Gaps = 38/300 (12%) Query: 380 TGVPTTDISATQPGKVTV---ALVDKDSTPLVGKVVSFSSTLGNFLPTQGTALTDSLGRA 436 T SA G + A V K+ VSF+ G + + +A T+ G+A Sbjct: 561 TDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKA 620 Query: 437 SITLTAGSIEGAGEITATYGTAKAIIGFVTAGDEIDPVEASPEISFDIYDCNDVATWDKA 496 ++TL + G++ + TA + + A+ I D T KA Sbjct: 621 TVTLKSDKP---GQVVVSAKTA----------EMTSALNANAVIFVD--QTKASITEIKA 665 Query: 497 LKNFEVCKATDNITNDKPGIVGAKVTRSGSTQALQQVLITAATTIGAISPSSGTAITNAE 556 K V D IT KV + + Q+V T TT+G +S S+ T+ Sbjct: 666 DKTTAVANGQDAIT------YTVKVMKGDKPVSNQEV--TFTTTLGKLSNSTEK--TDTN 715 Query: 557 GKAILDLYANGNVGAGEISLKVKDVTATKAFEIGRVNISLKLETSLGGNLLPAGGSTI-- 614 G A + L + G +S +V DV A ++ + ++ + G+ + Sbjct: 716 GYAKVTLTST-TPGKSLVSARVSDV----AVDVKAPEVEFFTTLTIDDGNIEIVGTGVKG 770 Query: 615 -LDVTVLNPDGS--LATGQPFTLVFTSECQASNKAIIDSPVITNGGKGYATYRSTGCETQ 671 L L A+G + S A S +T KG T + Q Sbjct: 771 KLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQ 830
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 2e-18 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 4/110 (3%) Query: 8 IIIADDHPLFRNALRQALSSAFEHTQWYEADSADALQSVLDSQTVNYDLVLLDLQMPGSH 67 I++ADD R L QALS A + +A L + + DLV+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVR--ITSNAATLWRWIAAGD--GDLVVTDVVMPDEN 61 Query: 68 GYSTLIHLRSHYPELPVVVISAHEDINTISRAIHYGGSGFIPKSASMETL 117 + L ++ P+LPV+V+SA T +A G ++PK + L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 28.7 bits (64), Expect = 0.010 Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 21/97 (21%) Query: 15 AIEQRINQSEARVIKAVFPSITNHHNTLFGGEALAWMDETAFIAATRFCRKTLVTVSSDR 74 +E + A+V+ P++ N +A+ ET + V V+ Sbjct: 350 LLEN---EGSAQVVSR--PTLLTQENA----QAVIDHSETYY-----------VKVTGKE 389 Query: 75 IDFKKPIPAGTLAELIARVIHVGNTSLKVEVNIFVED 111 + K I GT+ + RV+ G+ S ++ +N+ +ED Sbjct: 390 VAELKGITYGTMLRMTPRVLTQGDKS-EISLNLHIED 425
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 302 bits (775), Expect = 3e-95 Identities = 110/418 (26%), Positives = 188/418 (44%), Gaps = 65/418 (15%) Query: 384 QPGDVLVTDMTDPDWEPIMK-RASAIVTNRGGRTCHAAIIARELGVPAVVGCGDVTDRIK 442 + ++ D+T D + K T+ GGRT H+AI++R L +PAVVG +VT++I+ Sbjct: 155 EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQ 214 Query: 443 NGQLVTVSCAEG---------DTGYIYEGKQEFEVVSNRVDALPALP--------MKIMM 485 +G +V V EG + E + FE L P +++ Sbjct: 215 HGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAA 274 Query: 486 NVGNPDRAFDFARLPNEGVGLARLEFIINRMIGIHPKALLEFNQQDAALQEEINEMIAGY 545 N+G P EG+GL R EF+ + +D EE E Y Sbjct: 275 NIGTPKDVDGVLANGGEGIGLYRTEFL--------------YMDRDQLPTEE--EQFEAY 318 Query: 546 DSPVEFYIARLVEGIASIGSAFYPKKVIVRMSDFKSNEYANLVGGDRYEPEEENPMLGFR 605 V+ K V++R D ++ + + P+E NP LGFR Sbjct: 319 KEVVQ---------------RMDGKPVVIRTLDIGGDKELSYL----QLPKELNPFLGFR 359 Query: 606 GASRYISESFRDCFALECEAIKRVRNEMGLKNVEVMIPFVRTVKEAEQVIELLKEQGLER 665 + + +D F + A+ R N++VM P + T++E Q +++E+ + Sbjct: 360 AIRLCLEK--QDIFRTQLRALLRAS---TYGNLKVMFPMIATLEELRQAKAIMQEEKDKL 414 Query: 666 GKDG------LRVIMMCEVPSNALLADQFLEHFDGFSIGSNDLTQLSLGLDRDSGIISHL 719 +G + V +M E+PS A+ A+ F + D FSIG+NDL Q ++ DR + +S+L Sbjct: 415 LSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYL 474 Query: 720 FDERNEAVKILLSMAIKAAKAKGAYIGICGQGPSDHADFAAWLVEQGIDTVSLNPDTV 777 + + A+ L+ M IKAA ++G ++G+CG+ D L+ G+D S++ ++ Sbjct: 475 YQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDE-VAIPLLLGLGLDEFSMSATSI 531
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 198 bits (506), Expect = 1e-58 Identities = 93/279 (33%), Positives = 140/279 (50%), Gaps = 27/279 (9%) Query: 225 GQGVTVAVLDTGYDLDHNDLAEQVLVSKDFTYSSNG----IDDLNGHGTHTAATIAGTGV 280 G+GV VAVLDTG D DH DL +++ ++FT G D NGHGTH A TIA T Sbjct: 40 GRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATEN 99 Query: 281 ESNGRWAGMAPGAKLLVGKVLTNAGSGSTSGILSGMQWAVAQGADVVSMSLGGSGTSCTG 340 E+ G+AP A LL+ KVL GSG I+ G+ +A+ Q D++SMSLGG Sbjct: 100 ENGV--VGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPE-DVPE 156 Query: 341 PLVDMVEALSDKALFVVSAGNS----FTRETVGIPGCAPSALTVGAVDRDNHTASFSSRG 396 + +A++ + L + +AGN + +G PGC ++VGA++ D H + FS+ Sbjct: 157 LHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSN 216 Query: 397 PSPDGHSAKPDIASQGVDVVSAASGGFGSTAYRALSGTSMSAPHVSGGAAIVMQARP--- 453 D+ + G D++S GG Y SGTSM+ PHV+G A++ Q Sbjct: 217 NE-------VDLVAPGEDILSTVPGG----KYATFSGTSMATPHVAGALALIKQLANASF 265 Query: 454 --ELSPRQVKEVLTSSVLPNDSHVLEQGAGPMDVNRAIA 490 +L+ ++ L +P + +G G + + Sbjct: 266 ERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEE 304
>INTIMIN#Intimin signature. Length = 939 Score = 31.2 bits (70), Expect = 0.017 Identities = 38/154 (24%), Positives = 57/154 (37%), Gaps = 15/154 (9%) Query: 134 VDSLSISVADEVAYYTDLNKQLLAIVDETAKAGANQEIAIKAAAFSAYLQMKERAGIERA 193 V LS S ++ LNK L + E KA Q+I + G A Sbjct: 73 VADLSKSQDINLSTIWSLNKHLYSSESEMMKAEPGQQIILPLKKLPFEYSALPLLG--SA 130 Query: 194 VLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVDGIRQLQ----NGNEVKE 249 L + G AG K+ K V++ N ++ L A QLQ NG+ K+ Sbjct: 131 PLVAAGGVAGHTNKL-TKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKD 189 Query: 250 VEALRQIATDQDNQKIQQQNPEDWFAK-STARID 282 IA +Q + ++Q W TA ++ Sbjct: 190 T--ALGIAGNQASSQLQ-----AWLQHYGTAEVN 216
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.038 Identities = 19/146 (13%), Positives = 42/146 (28%), Gaps = 15/146 (10%) Query: 68 DPVKADSVL----DTRIRAELLAMDWQ-RALGLAEGKLSVVDINLAPIPLAYGIINANKL 122 + V+ VL A+ L L + + ++ ++ L + Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 123 IFSRDEGRRMQEESRIMSQ----------MELDYSAPSHFIILDNAYITSLSLSLSQYQA 172 + E ++ S I Q EL+ + A I ++ Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 173 ELGELRQLLSQRSLSNLEYRAAERTL 198 L + LL +++++ E Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKY 261
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 29.1 bits (65), Expect = 0.015 Identities = 13/53 (24%), Positives = 26/53 (49%), Gaps = 7/53 (13%) Query: 60 FPDTFESSDTAVITRFFESLKAQLKADYLAKLRDTSLGQVHESELFYLWVKEI 112 F S D +++ F ++L YL +++ G + + +YLW+KE+ Sbjct: 520 FSKVVSSKDKSLVYSFLDNL-----MSYLETIKND--GPIDTDKKYYLWLKEV 565
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 320 bits (821), Expect = e-107 Identities = 121/344 (35%), Positives = 176/344 (51%), Gaps = 28/344 (8%) Query: 152 FDDIITLDPEMLLLKAKAQVLASHEVSVLICGESGTGKEMFARAIHNASARRDKPFVAIN 211 ++ M + L +++++I GESGTGKE+ ARA+H+ RR+ PFVAIN Sbjct: 136 GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAIN 195 Query: 212 CGAFPSELIDSILFGHKKGAFTGAVSDKVGVFELAHSGTLFLDEFGELDSSAQVRLLRVL 271 A P +LI+S LFGH+KGAFTGA + G FE A GTLFLDE G++ AQ RLLRVL Sbjct: 196 MAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 272 QDGKFTRLGDSKERSSNFHLITATNRDLMADVSKGRFREDLFYRVAIGVLSLPPLRSRQS 331 Q G++T +G S+ ++ ATN+DL +++G FREDL+YR+ + L LPPLR R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 332 DLDHLADQFTAMLTQEYPSLGGKKISTAAKKIISNHRWPGNIRELKATILRAALWSETAV 391 D+ L F +E L K+ A +++ H WPGN+REL+ + R V Sbjct: 316 DIPDLVRHFVQQAEKEG--LDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 392 LEEVDIRRAILSTF---------QNSESILERD----------------ISKGVDINSII 426 + I + S S S+ + + ++ Sbjct: 374 ITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVL 433 Query: 427 DLVERHYLERGLAFTSGNKRKAALLLGYNNHQTLNNRLKKLGLE 470 +E + L T GN+ KAA LLG N TL ++++LG+ Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGL-NRNTLRKKIRELGVS 476
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.032 Identities = 10/75 (13%), Positives = 29/75 (38%), Gaps = 10/75 (13%) Query: 106 DLQALKHQLSQAHGANSQLVQQLQQLQ----------SELDEQQNKNLTLENALTSATAK 155 + + ++++ + +L + EQ+NK + N L ++ Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ 274 Query: 156 LKHLEAQYQQAQQAL 170 L+ +E++ A++ Sbjct: 275 LEQIESEILSAKEEY 289
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 40.0 bits (93), Expect = 6e-06 Identities = 29/186 (15%), Positives = 60/186 (32%), Gaps = 38/186 (20%) Query: 45 TDGAHGVLIKPDWIVTAAH-ATFCITPGSDIR-----ILDTDHKVDSVFVHKKYQPGISH 98 T A GV++ D ++T H ++ I ++ + + Sbjct: 101 TFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG 160 Query: 99 DIALIKL------VDPVTDVTPARLYEQSDELGKNIWFIGAGGTGNGLTGQTVDNGANAG 152 D+A++K V PA + + E N G G+ Sbjct: 161 DLAIVKFSPNEQNKHIGEVVKPATM-SNNAETQVNQNITVTGYPGD----------KPVA 209 Query: 153 VLRKAQNSVEFAQGPLLTFTFDSGDEALPLEGVSGGGDSGGP---AYLTLEGIHYLLGIS 209 + +++ + + +G + + + GG+SG P + GIH+ G+ Sbjct: 210 TMWESKGKITYLKGEAMQYDLS-----------TTGGNSGSPVFNEKNEVIGIHW-GGVP 257 Query: 210 SRVGGG 215 + G Sbjct: 258 NEFNGA 263
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 31.1 bits (70), Expect = 0.003 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 1/65 (1%) Query: 92 LLSKERGGQALDCQCLGIIPTEIDELDRQILKAEGLPLPHMGWNQLTFSNPSQVHPLFTG 151 L+S E L Q G P+ + I + G+P+ + WN T S P QV+ F+ Sbjct: 48 LISGENAVDILAVQEAGSPPSTAVDTGTLI-PSPGIPVRELIWNLSTNSRPQQVYIYFSA 106 Query: 152 VPAGS 156 V A Sbjct: 107 VDALG 111
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 113 bits (284), Expect = 1e-36 Identities = 31/89 (34%), Positives = 56/89 (62%), Gaps = 1/89 (1%) Query: 2 TKSELIEKLATRQSQLSAKEVEGAIKEMLEQMATTLESGDRIEIRGFGSFSLHYRAPRTG 61 K +LI K+A ++L+ K+ A+ + +++ L G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAKVA-EATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGSSVELEGKYVPHFKPGKELRERV 90 RNP+TG ++++ VP FK GK L++ V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.7 bits (240), Expect = 6e-26 Identities = 72/258 (27%), Positives = 119/258 (46%), Gaps = 14/258 (5%) Query: 10 QGKNVVVVGGTSGINLAIANAFAQAGANVTVASRSQDKIDAAV--LQLKQSNPDGIHLGV 67 +GK + G GI A+A A GA++ + +K++ V L+ + + + Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA-- 64 Query: 68 SFDVRDLAAVEQGFEAIASEFGFIDVLVSGAAGNFPATAAKLSANGFKAVMDIDLLGSFQ 127 DVRD AA+++ I E G ID+LV+ A P LS ++A ++ G F Sbjct: 65 --DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 128 VLK-TAYPLLRRPQGNIIQISAPQASIAMPMQAHVCAAKAGVDMLTRTLAVEWGCEGIRI 186 + + ++ R G+I+ + + A + A ++KA M T+ L +E IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 187 NSIIPGPIADTEGFNRLAPSAALQQQVAQS-------VPLKRNGEGQDIANAAMFLGSEY 239 N + PG ++ A +Q + S +PLK+ + DIA+A +FL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 240 ASYITGVVLPVDGGWSLG 257 A +IT L VDGG +LG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 30.9 bits (70), Expect = 0.009 Identities = 34/161 (21%), Positives = 61/161 (37%), Gaps = 22/161 (13%) Query: 19 IKGLLLGSLVSMLLSTQAHAAIHPMDESILAKQIADIAPRHS-QVALLARDLSTNTLLYS 77 I+ ++ L ++ L+ A +QI + S +V ++ DL++ L + Sbjct: 4 IRLCIISLLATLPLAVHASPQPL--------EQIKLSESQLSGRVGMIEMDLASGRTLTA 55 Query: 78 QQADTLFIPASTQKVLTAVTALATLGPDFRYVTE--------LWSDAPIRQGHIAGSVYL 129 +AD F ST KV+ LA + + L +P+ + H+A + + Sbjct: 56 WRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTV 115 Query: 130 RFSGDPTLTQDDLKA---LFAHLQKQGITSIEGHLYLIGDK 167 +T D A L A + G + L IGD Sbjct: 116 GELCAAAITMSDNSAANLLLATV--GGPAGLTAFLRQIGDN 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 7e-16 Identities = 34/158 (21%), Positives = 66/158 (41%), Gaps = 1/158 (0%) Query: 875 GHILLAEDSPANQIIAGTMLTKAGFDITYACNGLEAVKLVAEKPFDLVLMDVRMPEMDGL 934 IL+A+D A + + L++AG+D+ N + +A DLV+ DV MP+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 935 EATEVILQNHPEQVILAMSANVMKEEIEHCYRVGMKDFIAKPVKQKTLLHAIQKWLPNAV 994 + I + P+ +L MSA G D++ KP L+ I + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 995 VSLPSSHKPAENTASLL-DEQLLAELEQTLGKASLSNM 1031 +++ L+ + E+ + L + +++ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDL 161
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 472 bits (1217), Expect = e-166 Identities = 147/477 (30%), Positives = 252/477 (52%), Gaps = 12/477 (2%) Query: 4 SALLVEDSMSLGALYTEYLRAEDINVTHVHYGADALKELSNWQPDLLILDIKLPDMSGLD 63 + L+ +D ++ + + L +V A + ++ DL++ D+ +PD + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 ILKQVQQSHPHISTIMITAHGSIDIAIDAMRSGAFDFLVKPFDAKRLSITVRNALKQKQL 123 +L +++++ P + ++++A + AI A GA+D+L KPFD L + AL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 124 LELVTQYENSLPKGHYQGFIGDSLAMQSVYKTIDCVANSKASVFIMGESGTGKEVCAQAI 183 + +G S AMQ +Y+ + + + ++ I GESGTGKE+ A+A+ Sbjct: 125 R----PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 184 HQVGNRADKPFIALNCASIPKELIESEIFGHCKGAFTGAHNNRDGAATRADGGTLFLDEI 243 H G R + PF+A+N A+IP++LIESE+FGH KGAFTGA G +A+GGTLFLDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 244 CEMDLELQSKLLRFIQTGTFQRVGGSKEEHVDIRFISATNREPWEEVKLGHFREDLFYRL 303 +M ++ Q++LLR +Q G + VGG D+R ++ATN++ + + G FREDL+YRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 304 HVIPIELPPLRARGNDVLLLAKQLLKTYSKEEGKKFIDFNPQAAAMLQAYDWPGNVRQLQ 363 +V+P+ LPPLR R D+ L + ++ K EG F+ +A +++A+ WPGNVR+L+ Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEK-EGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 364 NVIRQIVVLNDASHVEPSMFPTPLKPLAQPQTKAQLQTKMQVEATKVDIDTLVQVASREL 423 N++R++ L + + L+ + ++ A + ++ Q + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRS-------EIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 424 LSESTQEAHTHTADQQRIQPLWLTEKQTIEGAIALCDGNVPKAAALLDISPSTIYRK 480 + L E I A+ GN KAA LL ++ +T+ +K Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK 469
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 336 bits (864), Expect = e-113 Identities = 112/347 (32%), Positives = 184/347 (53%), Gaps = 30/347 (8%) Query: 178 ITAKSLVMQDTVSKAKRVAASEVPVLILGETGTGKEVMAQAIHRASLRAGQPLKIVNCGA 237 + +S MQ+ R+ +++ ++I GE+GTGKE++A+A+H R P +N A Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA 198 Query: 238 LAPNLVDSTLFGHKKGAFTGADKDYPGLFEQANNGTLFLDEVGELPLDVQVKLLRALQQG 297 + +L++S LFGH+KGAFTGA G FEQA GTLFLDE+G++P+D Q +LLR LQQG Sbjct: 199 IPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQG 258 Query: 298 EVTRLGDTKTINVDVRVIAATHQDLNKLVANGKFREDLFYRLAVGVIRIPSLRERQEDIP 357 E T +G I DVR++AAT++DL + + G FREDL+YRL V +R+P LR+R EDIP Sbjct: 259 EYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIP 318 Query: 358 LIVGQLVDQINHSASKHPQYISKKISEKGIKFLSSQYWPGNIRDLWSTLNRAFLWSDTSI 417 +V V Q K+ ++ ++ + + WPGN+R+L + + R + Sbjct: 319 DLVRHFVQQAEKEGLD-----VKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDV 373 Query: 418 MDEYELSQAMLT-----RSQVVEDVPISLTFNDKVD-------------------IVQLT 453 + + + + + SL+ + V+ ++ Sbjct: 374 ITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVL 433 Query: 454 DNLQKNYVVAALKASGNVKKHATQMLGLKDHQTLTNWMKRLGIATEK 500 ++ ++AAL A+ + A +LGL + TL ++ LG++ + Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGL-NRNTLRKKIRELGVSVYR 479
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.015 Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 164 RDLNKLSSTVFIINKMD-EVTDLSDPTLFSEQAAIKTETLKEKLQRAASLTDEEVKALRI 222 R L ++ V IIN M+ E+ LSD L KT + +L++ L + +A + Sbjct: 16 RTLRRMRKVVNIINAMEPEMEKLSDEELKG-----KTAEFRARLEKGEVLENLIPEAFAV 70 Query: 223 V 223 V Sbjct: 71 V 71
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 32.9 bits (74), Expect = 0.001 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 97 TPNEYLSLLNKYTNENIDGFDLQGLGQANSIVLSVPDRHVAPIIVRRLLQAAREQRCVDV 156 T + LL N++ +DL+ +G NS+++S+ + + LL+AA Q Sbjct: 69 TQEDTAKLLQSTVKHNLNNYDLRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGAR 128 Query: 157 DYVSLEHPSERGRNIAPHTLVFDGFRWHV 185 +VS S AP T V +G R H+ Sbjct: 129 GHVSSHSHSALH---APGTPVREGLRSHL 154
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.9 bits (77), Expect = 0.006 Identities = 56/290 (19%), Positives = 110/290 (37%), Gaps = 15/290 (5%) Query: 309 EKSDQDLTECRSKLDTSVENRTSLEQESEQLKPRLASAVEGEIFYKQGKQASVSLLKKEA 368 + + E K D S+ + S QE E K L A+EG + + A + L+ E Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 369 Q-LYESLSLSQLADEGADASRNKVEQANQDILDIQAQL-ADVQERFILLEKKAGQYRNAK 426 L + + A EGA + + +A L A E LE Sbjct: 151 AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210 Query: 427 SLLDSVKSWCGDSFELAKLKGMIEEYTAQSKQLALEADQLGNKLNSAE-NINEIHAKAAS 485 + + ++++ E A L + + + K+ + E + A+ A Sbjct: 211 AKIKTLEA------EKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE 264 Query: 486 LIRRAGDSIDPNVAKNWFISTELRLEEERPLAVSLEQMRNGLSALKRNHRTVNRMLDRFK 545 L + +++ + A + I T + L + + L N +++ R LD + Sbjct: 265 LEKALEGAMNFSTADSAKIKTLEAEKAA--LEAEKADLEHQSQVLNANRQSLRRDLDASR 322 Query: 546 QAKLPRMPSNESEYQQLTEDRGEALESAKEVKASVDARYEDERHIQEELK 595 +AK E+E+Q+L E + S + ++ +DA E ++ ++ E + Sbjct: 323 EAK----KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQ 368
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.0 bits (122), Expect = 8e-09 Identities = 22/90 (24%), Positives = 37/90 (41%), Gaps = 9/90 (10%) Query: 28 KILVVDDEPDVHTVTKLALSRFRLDGRALTFINAYSGEQAKELLAQEQDIAVAFIDVVME 87 ILV DD+ + TV ALSR D R + +A + DVVM Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-----TSNAATLWRWIAAGD-GDLVVTDVVMP 58 Query: 88 SDHAGLELVKWIREVQVNKNIRLILRTGQP 117 D +L+ I++ ++ +++ + Q Sbjct: 59 -DENAFDLLPRIKK--ARPDLPVLVMSAQN 85
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 42.0 bits (98), Expect = 1e-05 Identities = 60/379 (15%), Positives = 126/379 (33%), Gaps = 15/379 (3%) Query: 289 DTLQSARTKYYQLRGSLLDSFNKTVWSIELSKTALTSKQETLKKSVSDLHAELQAFKPEH 348 ++T + D F +++L + L+ + LK +L EL K + Sbjct: 42 AVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKL 101 Query: 349 DRLRSMESEAKSDHKSAVNRLHEIDTAIKIVEECRSKLLPLCPADSRNDQSLLAVLDEQI 408 + SE S + R +++ A++ + A + ++ A L + Sbjct: 102 RKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADS----AKIKTLEAEKAALAARK 157 Query: 409 KDCETEIASLLDQAAAIE-RMKNFTSVINRNKEELELRRKALENIDSKLSFLDTITPDAA 467 D E + ++ + A ++K + + KALE + + Sbjct: 158 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLE 217 Query: 468 SILLSINNNFAKLEITPSAEQKTVIQSFAALFASEAEAVYFCGAILPGVNLKRFNNADIK 527 + ++ A LE A + EAE Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFST 277 Query: 528 RELESVIDVLIAKIEHDEKQRATISQNCRLSKERQAEK--LKECTEDLEELRLQKQNLQ- 584 + + + K + ++ Q+ L+ RQ+ + L E ++L + Q L+ Sbjct: 278 ADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 585 GTELLNTQKTKAESDVIRSKE-------EFDKATREFKSASEKFENLSRRYNLANEELTS 637 ++ + D+ S+E E K + K + ++L R + + E Sbjct: 338 QNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 397 Query: 638 VGNPLRELNNQISRLEDLE 656 V L E N++++ LE L Sbjct: 398 VEKALEEANSKLAALEKLN 416
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 4e-07 Identities = 10/65 (15%), Positives = 24/65 (36%) Query: 524 SLLLVDDNLFNLEICRSVLESHFTHIHSADRAEEALRLFSTQRPFIVIVDYRLKDTDGLA 583 ++L+ DD+ + L + A R + +V+ D + D + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 584 LIKQM 588 L+ ++ Sbjct: 65 LLPRI 69
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.7 bits (168), Expect = 2e-14 Identities = 36/199 (18%), Positives = 70/199 (35%), Gaps = 19/199 (9%) Query: 255 KILLVDDQQSMVDYFSSLLRSHGLMVKGMTKPEQVLPTLEQFEPDLFIFDLYMPDVNGLE 314 IL+ DD ++ + L G V+ + + + + DL + D+ MPD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 315 LAKMIRQLDKYSSSPILVLSSDDTMQNKVSIIQAGSDDLISKQTAP--SLFVTQVISRAQ 372 L I++ P+LV+S+ +T + + G+ D + K + + Sbjct: 65 LLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 373 RGHDIRSSASRDSLTGLLNHTQILVAARRCYNLAKRINSSVCIAMLDLDHFKQVNDTYGH 432 + + L+ + + R + + ++ I G Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT--------------GE 168 Query: 433 SGGDKVLLAFAHLLQQSLR 451 SG K L+A A L R Sbjct: 169 SGTGKELVARA-LHDYGKR 186 Score = 53.7 bits (129), Expect = 1e-09 Identities = 27/123 (21%), Positives = 55/123 (44%), Gaps = 1/123 (0%) Query: 131 RIAIVEDDSNVGAMITKQLHEFGFNVQHFLNFTDFLGIQNTSPFDLVLLDLILPDYTEAA 190 I + +DD+ + ++ + L G++V+ N DLV+ D+++PD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 191 LFTAATEFEKNNTRVFVLSSRGDFEMRLLAIRANVSEYFVKPAETTLLVRKIHQWLKMSE 250 L + + + V V+S++ F + A +Y KP + T L+ I + L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 251 KQP 253 ++P Sbjct: 124 RRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 5e-14 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 7/107 (6%) Query: 3 IKVLVVDDSALIRNLLGKMIE-ADPELSLVGMAADAYMAKDMVNQHRPDVITLDIEMPKV 61 +LV DD A IR +L + + A ++ + AA + D++ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL---WRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGLTFLDRLMKARPTAVVMISSLTEEG-ADATFNALGLGAVDFIPKP 107 + L R+ KARP V++ ++ + A GA D++PKP Sbjct: 61 NAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP 105
>PF07520#Virulence protein SrfB Length = 1041 Score = 31.1 bits (70), Expect = 0.015 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 7/77 (9%) Query: 266 KAKRFTPAQDQQLQKYLVRRVLIEQDDNFKD---WADNLLPEMKSDDMFERRLRWAIREQ 322 K + F D + ++R+ ++D N D W + L EM D R +I E+ Sbjct: 175 KPREFRLVSDPGAMSWFLQRLEADEDGNAVDLQLWVSDWLKEMFLDFKRAERPGRSISEE 234 Query: 323 DS----THIARYLDLLS 335 + H ARYL L Sbjct: 235 NLPHMFEHWARYLSYLQ 251
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.6 bits (105), Expect = 2e-08 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 6/94 (6%) Query: 41 HMKNGDSVIFLALSEDNEPLGFAQLYPSFSSVAMKRMWYLNDLYVSENARKKGVGRALLQ 100 +++ FL +N +G ++ +++ A + D+ V+++ RKKGVG ALL Sbjct: 59 YVEEEGKAAFLYYL-ENNCIGRIKIRSNWNGYA-----LIEDIAVAKDYRKKGVGTALLH 112 Query: 101 KVAAFAKNTDAITVKLATAVSNEKAKSLYESEGY 134 K +AK + L T N A Y + Sbjct: 113 KAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 105 bits (263), Expect = 8e-27 Identities = 70/368 (19%), Positives = 139/368 (37%), Gaps = 62/368 (16%) Query: 22 VGIDLGTTNSLVAAVRSGVTATLPDENGQHSLPSIVRYTQDGIEVGQVAALSSAQDPKNT 81 + IDLGT N+L+ G+ + PS+V QD + Sbjct: 13 LSIDLGTANTLIYVKGQGIVL---------NEPSVVAIRQDR------------AGSPKS 51 Query: 82 IVSV----KRFMGRSLTDIQSGEQAFPYQFEASENGLPLFVTP--QGQVNPVQVSAEILR 135 + +V K+ +GR+ +I + + P G + V+ ++L+ Sbjct: 52 VAAVGHDAKQMLGRTPGNIAA-------------------IRPMKDGVIADFFVTEKMLQ 92 Query: 136 PLVERA-EKTLGGELQGVVITVPAYFDDAQRQGTKDAASLLGVKVLRLLNEPTAAAIAYG 194 +++ + V++ VP +R+ +++A G + + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSKQEGVIAIYDLGGGTFDISILRLNRGVFEVLATGGDSALGGDDFDHLLQAHMQQVWQ 254 L + + D+GGGT +++++ LN V +GGD FD + ++++ + Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 LANIDSQLSRQLLIEARRVKEALTDASEVEASL---TLADGTVLKQLVTKAEFDCLISAL 311 I + ++ E + A E + LA+G + E + Sbjct: 208 SL-IGEATAERIKHE---IGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP 263 Query: 312 VKKTIASCRRTLRD-AGVTADEVLE--TVMVGGSTRVPLVREQVEAFFGKAPLTSIDPDR 368 + +++ L A ++ E V+ GG + + + G + + DP Sbjct: 264 LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLT 323 Query: 369 VVAIGAAI 376 VA G Sbjct: 324 CVARGGGK 331
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 619 bits (1598), Expect = 0.0 Identities = 247/1036 (23%), Positives = 467/1036 (45%), Gaps = 35/1036 (3%) Query: 2 IIKAAISRRISTAVLAFGLAIFGALNLNMLPVDFLPSVKYPLIKLSIIWQGATPEDIDQN 61 + I R I VLA L + GAL + LPV P++ P + +S + GA + + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 LADPIERELASVDGLDYLSS-SAIEGLYQLDVNYRYGVDVDVAYQDTLAAFNRSTKNLPV 120 + IE+ + +D L Y+SS S G + + ++ G D D+A +T LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DIEAPVIIKADPSQLPIVQAVFESESMDLTQ--LRTWIDSWLTQRLLSASGVAAIDVAGG 178 +++ I S ++ A F S++ TQ + ++ S + L +GV + + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 179 LEREIRIFVDDEKLEAHGLDLTTLERVLSAENLQRVGGRVT------GKYRENIVRVMGE 232 + +RI++D + L + L + L +N Q G++ G+ + Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 233 FSQLAVIQDLVLSRDSSGSIVRIRDVAEVKDSHEDIRMLTRLNGHPAVKVNVIKQADANT 292 F + L +S GS+VR++DVA V+ E+ ++ R+NG PA + + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 293 VTTVDNVEDRLADLAPSFPKDIKFTLVENQADYINDSIRGVRNTALEAMALVVLVLFVFL 352 + T ++ +LA+L P FP+ +K + ++ SI V T EA+ LV LV+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 353 GNSRQVLIIAIALPFALLVNFFLMHLAGFSLNIFSLGGLVVAIGVLPDTSIIVVENISRL 412 N R LI IA+P LL F ++ G+S+N ++ G+V+AIG+L D +I+VVEN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER- 418 Query: 413 RSLHDKANPQSISEEATLEVGGAIMAATVTFIALFVPFLLVPGLITLLFKELVLVILGLM 472 + DK P+ +E++ ++ GA++ + A+F+P G ++++ + I+ M Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 473 IIAGLAAITLTPMLGGVLLKANQRE--------FAFSEKINHGLRWAYGALLHSALQFRL 524 ++ L A+ LTP L LLK E F + Y + L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 525 TTIFIFIGVAIGGVLLFKSAGSEFFPAVDDGRIVVKIRMPAGANLARMDAIAQQVEALVI 584 + I+ + G V+LF S F P D G + I++PAGA R + QV + Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 585 GDQR--VRSVFTLSGGAVRGLYTNKIGNEGEVDIELVPSSER---KITTTEYIKELRPKV 639 +++ V SVFT++G + G N G + L P ER + + I + ++ Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNA----GMAFVSLKPWEERNGDENSAEAVIHRAKMEL 654 Query: 640 AKLLAPGAILAVNQAKMRGIRSVGQAEIE-VEINGSEVDTLFDVANKLAAKLAERP-ELT 697 K + G ++ N + + + + E ++ G D L N+L A+ P L Sbjct: 655 GK-IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLV 713 Query: 698 NVYVSLDSSKPEWQVDIDRTLAAEHGLSTKEIAHVLNGYINGSVPTRYREASELYDIRII 757 +V + ++++++D+ A G+S +I ++ + G+ + + + + + Sbjct: 714 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQ 773 Query: 758 MPESQLRSRSDVENISIATPSGHYVRLKDVAKVTAATGPVEIIRKNQIKQVIVRCDPSA- 816 DV+ + + + +G V G + R N + + ++ + + Sbjct: 774 ADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG 833 Query: 817 TDLNSAKELVTNILTETTWPTGYTYSIGGKALQMTQMQTTVQSILGYAVFFSFIVLAVQF 876 T A L+ N+ ++ P G Y G + Q +++ + F+ LA + Sbjct: 834 TSSGDAMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALY 891 Query: 877 NNLRLPLVILFAAPFCLTGIGYGLFFASQPFGATVIIAAMIVLAANVIDGVLLIQTA-ER 935 + +P+ ++ P + G+ +Q ++ + + + + +L+++ A + Sbjct: 892 ESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDL 951 Query: 936 QKQQGITLLKATFDAGLSRLRPRLMTVLPAVLGFMPLALAFEEGGELLRPMAAAAIGGLL 995 +++G +++AT A RLRP LMT L +LG +PLA++ G + +GG++ Sbjct: 952 MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMV 1011 Query: 996 LNVFVALFLVPVLYTF 1011 +A+F VPV + Sbjct: 1012 SATLLAIFFVPVFFVV 1027
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.007 Identities = 20/116 (17%), Positives = 42/116 (36%), Gaps = 9/116 (7%) Query: 70 IVLTGTIEP-TKVASLASPAEGPILNLVVREGDTVNLGQEILRIGRTHAA-------DSL 121 G + + + + ++V+EG++V G +L++ A SL Sbjct: 84 ATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143 Query: 122 QTSAAEEVRKQVLNLKRIETLVKQHTLPEEQLDEALSSLEKAKAALSQAKQALNDY 177 + E+ R Q+L + IE ++ S E+ S K+ + + Sbjct: 144 LQARLEQTRYQIL-SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 1e-05 Identities = 35/214 (16%), Positives = 74/214 (34%), Gaps = 25/214 (11%) Query: 192 DTLKAKAADIRNLVKEQRARRDGILQTAALTSDDELAAEFSRIEPEFAAATAAKEQSVAA 251 DTLK +++ ++ +++ R + L+ EL P+ E+ V Sbjct: 135 DTLKTQSSLLQARLEQTRYQ--------ILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 252 HLAALKQRDSAQQLFAEFTRLQELQAEALSLNEQQAQIATQTARLDVAKQAIRV------ 305 + +K+ Q + + + L++++A+ T AR++ + RV Sbjct: 187 LTSLIKE-----QFSTWQNQKYQKELN---LDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 306 --KPLLDNVLSREQEASLAAAQRDSVQSTHDAAKIALAQAETAAQEIIPLEHKLRDLEQQ 363 LL + + + K L Q E+ E++L + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK-EEYQLVTQLFK 297 Query: 364 HSHLSALVPQLAEFASLEQALAQAKEILQHTKLQ 397 + L L L LA+ +E Q + ++ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331 Score = 32.1 bits (73), Expect = 0.012 Identities = 26/218 (11%), Positives = 65/218 (29%), Gaps = 20/218 (9%) Query: 602 AAAQALQQLQEQIKTLQQQESTLTQQLELERERYREQEGKVERLSGQFAEKALRIPEEYR 661 L +L + T + L+ E+ R Q + E L ++ Sbjct: 119 RKGDVLLKL-TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 662 TL--EVLNQAIADNQQQLEQIKRQIDALRAAQQQAAQQSVAAQTALSAAIEHCNGAADLQ 719 + E + + + ++Q + Q + + + ++ + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE------NLSR 231 Query: 720 VQAQQ-ALLAALDNAGFTDRDALREALLTDEQMQALAEGIETYHRQCSLNQSQLTQLKTK 778 V+ + ++L + + A+ E + + + Y Q +S++ K + Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQ---ENKYVEAVNELRVYKSQLEQIESEILSAKEE 288 Query: 779 LSESTSPDLDALEALLTERLAQLKTAEEVWSQLNTRLT 816 T + E L +L+ + L L Sbjct: 289 YQLVT-------QLFKNEILDKLRQTTDNIGLLTLELA 319
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.1 bits (65), Expect = 0.021 Identities = 11/51 (21%), Positives = 21/51 (41%) Query: 198 YFNQKKYKKAVGVLEVMVPLFPDDGRLWVQLAQFYLMVEDYDKSLATYDLA 248 + KY+ A V + + L D R ++ L + YD ++ +Y Sbjct: 46 QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 107 bits (268), Expect = 6e-31 Identities = 37/169 (21%), Positives = 65/169 (38%), Gaps = 10/169 (5%) Query: 39 TPVIEITMDRQDAKAQNKPRVVPKPPPPPEQPQKPDTTPPDTSSNID----TSMSFNMGG 94 P E + K PKP P P+ P S N Sbjct: 75 EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP 134 Query: 95 VEAGGHSAGGFKLGNMMTRDGDATPIVRIEPQYPIAAARDGKEGWVQLRFTINELGGVDD 154 +A + + + R +PQYP A EG V+++F + G VD+ Sbjct: 135 ARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDN 194 Query: 155 VEVIQAEPKRLFDKEAIRALKKWKYKPKIVDGKPLKQPGMTVQLDFTLD 203 V+++ A+P +F++E A+++W+Y+P G+ V + F ++ Sbjct: 195 VQILSAKPANMFEREVKNAMRRWRYEP------GKPGSGIVVNILFKIN 237
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 82.3 bits (203), Expect = 3e-19 Identities = 100/419 (23%), Positives = 170/419 (40%), Gaps = 57/419 (13%) Query: 1 MNKTLVATALAALFLAPTVSAIEIYKDDKNAVEIGGFIDARVINTQGETEVVNG-ASRIN 59 M + ++A + AL A A EIY D N +++ G +D + ++ +G + + Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSK--DGDQTYMR 58 Query: 60 FGFSRE--LTHGWNAFAKLEWGVNPVGSSDIVYNNRFESVQDEFFYNRLGYAGISHDEYG 117 GF E + + + E+ V N E + RL +AG+ +YG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQ---------ANTTEGEGANSW-TRLAFAGLKFGDYG 108 Query: 118 TITIGKQWGAWYDVVYNTNYGFVWDGNAAGVYTFNKDDGAVNGVGRGDKVVQYRNS---- 173 + G+ +G YDV T+ + G+ ++ D + GR + V YRN+ Sbjct: 109 SFDYGRNYGVLYDVEGWTDMLPEFGGD-----SYTYADNYMT--GRANGVATYRNTDFFG 161 Query: 174 -IGDVSFAVQAQLKNSSFYTCDIENITEEAC---EVEWNAGKKEAQQVTYDYTYGGSVT- 228 + ++FA+Q Q KN S D+ T ++ ++ G TYD G S Sbjct: 162 LVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGA 221 Query: 229 -YKAADKLSLMVGINRGEFDIAYGNGDQKTAVDLIYGVGATWGDFDKDGLYVAA------ 281 Y +D+ + V GD+ A + G +D + +Y+A Sbjct: 222 AYTTSDRTNEQVNAGG-----TIAGGDKADA----WTAGLK---YDANNIYLATMYSETR 269 Query: 282 NVHKEENHDTDNIGRLIKDAYGVETLVSYKFDNGLRPFVSYNILDAGKDYVIQPNFNADP 341 N+ D G + E Y+FD GLRP VS+ ++ GKD + N N D Sbjct: 270 NMTPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSF-LMSKGKD-LTYNNVNGDD 327 Query: 342 NDVFKRQFVVVGLHFVWDPNTVLYVEARKDYSDFTSSDQAQEARMSLSEDDGIAIGIRY 400 D+ K + VG + ++ N YV+ + + D D +S DD +A+G+ Y Sbjct: 328 KDLVK--YADVGATYYFNKNFSTYVDYKINLLD---DDDPFYKDAGISTDDIVALGMVY 381
>PF06776#Invasion associated locus B Length = 214 Score = 28.4 bits (63), Expect = 0.021 Identities = 12/78 (15%), Positives = 20/78 (25%), Gaps = 12/78 (15%) Query: 159 AAAATGAAGTAAVVAAPAPTSAQAAVNATSLTAP-------VDTSKAAGANPQQ--MLQY 209 A GA A A A + + + GA +Q ++Q Sbjct: 44 LARRNGARLMLAGAMAIALSFGWSDRADAQGAVRSVHGDWQIRCDTPPGAKAEQCALIQ- 102 Query: 210 WWLQADEKTRKEFMSWAI 227 E ++ I Sbjct: 103 --SVVAEDRSNAGLTVII 118
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 28.7 bits (64), Expect = 0.048 Identities = 10/44 (22%), Positives = 19/44 (43%) Query: 346 FLNKFLKTKFKMTDEQIRKAFYHYLCYQSAMRISLRTSSKKAPI 389 LN+ L K+K + + Y+ CY S+ + + K + Sbjct: 95 LLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCM 138
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 30.3 bits (68), Expect = 0.014 Identities = 22/122 (18%), Positives = 40/122 (32%), Gaps = 23/122 (18%) Query: 242 FDRKVKLPQVSVLDYLIARQLDFDKYKSDYIHLFPFTKNYKKNISVFA----ALFESNRI 297 F+R + +VLD I R P ++ + A + F N Sbjct: 35 FNRTMYNFNFNVLDPYIVR---------------PVAVAWRDYVPQPARNGLSNFTGN-- 77 Query: 298 ELRGVEQILNRFFASLEYVASTRMSSDVAINTIVLMVGLIEQHLEMSELVRRQNSSDLSF 357 L ++N F + + +NTI+ M G I+ + ++R Sbjct: 78 -LEEPAVMVNYF-LQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGS 135 Query: 358 SL 359 +L Sbjct: 136 TL 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 42 TLAIVGEAGSGKSTLARILVGAEPRSGG 69 TL I GE+G+GK +AR L R G Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNG 189
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 30.1 bits (68), Expect = 0.025 Identities = 50/203 (24%), Positives = 83/203 (40%), Gaps = 37/203 (18%) Query: 428 MFSRD---DVPTA------------LNKPDVV-----KAAFSDTVLRQGLNSE-VIELEP 466 MFS D D+ TA LN+P VV +A +V G +++ ++ P Sbjct: 8 MFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTP 67 Query: 467 NHVVVIR-MKEHHDAGTMPLAEVKADIAERLKQDQANEAARAKAQELMTQVKAGATDVSL 525 ++ IR MK+ G + V + + + + + + ++ V GAT V Sbjct: 68 GNIAAIRPMKD----GVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVER 123 Query: 526 TA--KTKLGRGAQDVD------AAIVGKAFQMPTPTATPVVDTVGLANGYAVIALDKVNA 577 A ++ G GA++V AA +G + T + VVD G AVI+L+ V Sbjct: 124 RAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVY 183 Query: 578 AESV---SDELVNALKQRLNAQY 597 + SV D A+ + Y Sbjct: 184 SSSVRIGGDRFDEAIINYVRRNY 206
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (297), Expect = 8e-39 Identities = 52/88 (59%), Positives = 69/88 (78%) Query: 2 NKSELIEKIASGADISKAAAGRALDSFIAAVTEGLKEGDKISLVGFGTFEVRERAERTGR 61 NK +LI K+A +++K + A+D+ +AV+ L +G+K+ L+GFG FEVRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGQEIKIAAAKIPAFKAGKALKDAV 89 NPQTG+EIKI A+K+PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.006 Identities = 15/86 (17%), Positives = 35/86 (40%), Gaps = 6/86 (6%) Query: 286 AEATVVRSYVDWMTSVPWSQRSKIKRDLAKAQEVLDTDHYGLEKVKDRILEYLAVQSRVR 345 A+ V + DW+ + W + ++++ L D+ +++ + V Sbjct: 527 ADMNRVHPFRDWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVA 586 Query: 346 QLKGP------ILCLVGPPGVGKTSL 365 ++ P + L G G+GK++L Sbjct: 587 RVMEPGCKFDYSVVLEGTGGIGKSTL 612
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.018 Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 13/70 (18%) Query: 64 KLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLRNSSPKDGVELGKSNILLIGPTG 123 + P+ E + ++G+ A +Y RL + +++ G +G Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAA----MQEIYRVLARLMQT---------DLTLMITGESG 170 Query: 124 SGKTLLAETL 133 +GK L+A L Sbjct: 171 TGKELVARAL 180
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 39.1 bits (91), Expect = 6e-05 Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 47/148 (31%) Query: 14 NAGKSTLFNAL---TGANQQVG---------NW------SGVTVEKKTGHFTLNGADVYL 55 +AGK+TL +L +GA ++G + G+T++ F V + Sbjct: 13 DAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNI 72 Query: 56 TDLPGIYDLLPAGNSCDCSLDEQIAQQYLAEQRVDGIINLVDA-------TNIERHLYLT 108 D PG D +A+ Y + +DG I L+ A T I L Sbjct: 73 IDTPGHMDF--------------LAEVYRSLSVLDGAILLISAKDGVQAQTRI-----LF 113 Query: 109 AQLRELSIPMVVVLNKIDAAIKRGIRVD 136 LR++ IP + +NKID GI + Sbjct: 114 HALRKMGIPTIFFINKIDQN---GIDLS 138
>INTIMIN#Intimin signature. Length = 939 Score = 32.0 bits (72), Expect = 0.008 Identities = 23/114 (20%), Positives = 40/114 (35%), Gaps = 13/114 (11%) Query: 325 PSISSASMDANGTVTVAVTLSNPATGTV--------YSESADKLKFISDLRVYAN----W 372 S S+ D NG V +T + P V A +++F + L + Sbjct: 705 LSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764 Query: 373 GTSFDYSTRSARSIRLPESTPVSGSNGTYTYTISGLTVPAGTEADHGGLAIQGR 426 GT + + SG NG YT+ + A +A G + ++ + Sbjct: 765 GTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSAN-PAIASVDASSGQVTLKEK 817 Score = 30.4 bits (68), Expect = 0.024 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 5/81 (6%) Query: 325 PSISSASMDANGTVTVAVTLSNPATGTVYSESADKLKFISDLRVYANWGTSFDYSTRSAR 384 S +SA+ + +G TV + P V SA + S L AN D + S Sbjct: 607 LSANSANTNGSGKATVTLKSDKPGQVVV---SAKTAEMTSALN--ANAVIFVDQTKASIT 661 Query: 385 SIRLPESTPVSGSNGTYTYTI 405 I+ ++T V+ TYT+ Sbjct: 662 EIKADKTTAVANGQDAITYTV 682
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 116 bits (292), Expect = 1e-33 Identities = 83/259 (32%), Positives = 119/259 (45%), Gaps = 15/259 (5%) Query: 4 LQGKVAIITGASSGIGYATAKRFAREGAKLVLGARRGAILASLVDEIITQGGEAIYLAGD 63 ++GK+A ITGA+ GIG A A+ A +GA + L +V + + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VTDEVYASDLVALAVEQYGGLDIAFNNVGINGELGVDSDALSRAEWENTLTTNLTSAFLA 123 V D ++ A + G +DI N G+ + S LS EWE T + N T F A Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHS--LSDEEWEATFSVNSTGVFNA 123 Query: 124 AKYQLPQMLKRGAGSIIFTSSFVGYTIGFPQT--AAYAASKAGMIGLTQSLAVEYGARGI 181 ++ M+ R +GSI+ S P+T AAYA+SKA + T+ L +E I Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGV---PRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 182 RVNALLPGGTDTPMGREFANTPEAMAFV--------KNLHALKRLADPAEIAQSALYLAS 233 R N + PG T+T M V K LK+LA P++IA + L+L S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 234 DAASFTTGIALLVDGGVSI 252 A T L VDGG ++ Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 46.9 bits (111), Expect = 2e-09 Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Query: 39 YLKRNQGLSFVAVSDSLVIGAVLVGTD-GRRGYVQHLAVSSDFRGQGIGKSLIQKATDAL 97 Y++ +F+ ++ IG + + ++ ++ +AV+ D+R +G+G +L+ KA + Sbjct: 59 YVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWA 118 Query: 98 SRIGISKTHLFVLIENVTAQDFYTK 122 L N++A FY K Sbjct: 119 KENHFCGLMLETQDINISACHFYAK 143
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 143 bits (363), Expect = 7e-41 Identities = 70/210 (33%), Positives = 97/210 (46%), Gaps = 24/210 (11%) Query: 126 AGMKVCIIDSGLDSSNPDFNWNNITG----DNDSGTGNWYQNGGPHGTHVAGTIGAADNN 181 G+KV ++D+G D+ +PD I G D+D G +++ HGTHVAGTI A +N Sbjct: 41 RGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENE 100 Query: 182 IGVVGMAPGVPMHIVKVFNASGWGYSSDLAYAANKCSNAGAKIISMSLGGGAANNTEKNA 241 GVVG+AP + I+KV N G G + IISMSLGG A Sbjct: 101 NGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEA 160 Query: 242 FDAFTAAGGLVVAAAGNDGNSVRS-----YPAGYPSVMMIGANDANNKIADFSQYPSCVS 296 A+ LV+ AAGN+G+ YP Y V+ +GA + + ++FS Sbjct: 161 VKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNS----- 215 Query: 297 GRGKKAVNDDGICVEVTAGGVDTLSTYPAG 326 V++ A G D LST P G Sbjct: 216 ----------NNEVDLVAPGEDILSTVPGG 235 Score = 53.3 bits (128), Expect = 9e-10 Identities = 19/70 (27%), Positives = 27/70 (38%), Gaps = 7/70 (10%) Query: 447 YGFMSGTSMATPAVSGMAALVWSN-----HSQCTGTQIRNALKATAMDAGTVGKDNYFGY 501 Y SGTSMATP V+G AL+ T ++ L + G G Sbjct: 237 YATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGN 294 Query: 502 GIVNAKAADA 511 G++ A + Sbjct: 295 GLLYLTAVEE 304
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 38.4 bits (89), Expect = 2e-05 Identities = 44/166 (26%), Positives = 79/166 (47%), Gaps = 23/166 (13%) Query: 186 GVILTMTMVMFT----SAAIVREREQGNMEFLITTPVRPLELMLGKI----TPYVLVGFV 237 G++ T M T AA R Q E ++ T +R +++LG++ T L G Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 238 QLAIILSAGH-----LLFAVPIRGGLDSIALAAMLFICASLTLGLVISTIAKTQLQSMQM 292 + + G+ LL+A+P+ IAL + F +LG+V++ +A + + Sbjct: 132 IGVVAAALGYTQWLSLLYALPV------IALTGLAFA----SLGMVVTALAPSYDYFIFY 181 Query: 293 TVFILLPSILLSGFMFPYEAMPVAAQWIAEALPATHFMRMSRAIVL 338 ++ P + LSG +FP + +P+ Q A LP +H + + R I+L Sbjct: 182 QTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML 227
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.8 bits (124), Expect = 2e-09 Identities = 30/144 (20%), Positives = 50/144 (34%), Gaps = 9/144 (6%) Query: 51 TVERDRLTLTAPVGELINQINVVEGQQVQAGEVLLELDSTAAKARLGQRQAELKQA---- 106 T + ++ +I V EG+ V+ G+VLL+L + A+A + Q+ L QA Sbjct: 91 THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150 Query: 107 ---QAKLEEAVTGARSEDIDKARAALDGANASVKEVQQNFERTQR--LFKTKVLSQADLD 161 Q E + + + Q K + +LD Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD 210 Query: 162 AALAARDTSLAKQAEAEQSLRLLQ 185 A R T LA+ E R+ + Sbjct: 211 KKRAERLTVLARINRYENLSRVEK 234 Score = 49.4 bits (118), Expect = 8e-09 Identities = 32/239 (13%), Positives = 73/239 (30%), Gaps = 30/239 (12%) Query: 76 QQVQAGEVLLELDSTAAKARLGQRQAELKQAQAKLEEAVTGARSEDIDKARAALDGANAS 135 Q V EVL K + Q + Q + L+ + + A ++ Sbjct: 177 QNVSEEEVLRLTS--LIKEQFSTWQNQKYQKELNLD-----KKRAERLTVLARINRYENL 229 Query: 136 VKEVQQNFERTQRLFKTKVLS--------------QADLDAALAARDTSLAKQAEAEQSL 181 + + + L + ++ +L + + ++ A++ Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY 289 Query: 182 RLLQNGTRSEQLEQARAAVEAAMAGVAQEQKALKDLSLVAARS----AVVDTLPWRVGDR 237 +L+ ++E L++ R + + K + R+ V G Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 238 VAAGSQLIGLLAIEHPY-VRVYLPATWLDRVKAGSQVKILVDG----RAQPIAGTVRNI 291 V L+ ++ + V + + + G I V+ R + G V+NI Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNI 408
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.7 bits (165), Expect = 5e-16 Identities = 26/155 (16%), Positives = 56/155 (36%), Gaps = 6/155 (3%) Query: 31 SDARQRLIAAAVTLFSERSYPTVSTREIAREAEVDAALIRYYFDSKAGLFEQMVRETLEP 90 + RQ ++ A+ LFS++ + S EIA+ A V I ++F K+ LF ++ + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 91 VIARLREISSAQAPND---IGELMQTYYRVMAPNLGLPRLIVRVLQEGDGTEAYRIMLSV 147 + E + + + E++ L+ + + + ++ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 148 FEQILSLSRQWVESAL---VNAGLLKEGLDPNLVR 179 + S +E L + A +L L Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA 164
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.0 bits (59), Expect = 0.046 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 91 AKVAELLGDLQKVMEQEVSFDQVASLLQKGADAAAYAKSLIEQQGVEQAMQSLKQMALAS 150 +KV + DL+ ++ + +V + A + AK+ + VEQA+ LK + Sbjct: 758 SKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAKATGDFSRVEQALADLKN--FSK 815 Query: 151 EQFAQQ 156 EQ AQQ Sbjct: 816 EQLAQQ 821
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 0.005 Identities = 25/125 (20%), Positives = 38/125 (30%), Gaps = 10/125 (8%) Query: 1128 QLQTSSSQAALALLGQKPAPQVQAPIQTAAPVA----VAVATPVAPAQAPVVQALAAEPK 1183 +L + ++ ++ QA PV P P +APVV +PK Sbjct: 42 ELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE-KPKPK 100 Query: 1184 ATVVPVSEPKVQQPQVTQQVAQPQVQTVAAATRALSEKPVVQQIETAMMAVVADKTGYPV 1243 P KV+QP+ + A+ + P TA A T Sbjct: 101 PKPKPKPVKKVEQPK-----RDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVAS 155 Query: 1244 EMLEL 1248 L Sbjct: 156 GPRAL 160
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 58.3 bits (141), Expect = 2e-11 Identities = 32/203 (15%), Positives = 73/203 (35%), Gaps = 8/203 (3%) Query: 87 IALAKAKSDYETVLNSVKANNEGVKAAEAKLQAMRASYNNSVKDAER---QERLYRQDPG 143 + L K +++ TVL + + +++L + + QE Y + Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266 Query: 144 AISVRRLEIAQASRETASSQVTAAEADVRRAIEAAGVNGENNSQLLSARSAVNKAERDRQ 203 + V + ++ Q E S++ E + + + K E +Q Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQ 326 Query: 204 NTHVVAPSRGVITDLNT-DVGQFINAGAPAMTLIAIHDV-WISADLTENNLGNIKVGNRV 261 + + AP + L G + M ++ D ++A + ++G I VG Sbjct: 327 ASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNA 386 Query: 262 SILLDSMPGQLF---SGQIRSIG 281 I +++ P + G++++I Sbjct: 387 IIKVEAFPYTRYGYLVGKVKNIN 409
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 30.9 bits (69), Expect = 0.006 Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 218 IEQQLLTLPILYLSRYIVQHKADYYRLLNQVTREGDWQSWLLFMLKGVEQMASWTCGKIA 277 +EQQL L + H+ Y + + ++G Q + + +G+EQ + + A Sbjct: 40 LEQQLAQLQMQ-------AHEQGYQAGIAEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQA 92 Query: 278 AVRELMEQ-TSEYVRT--ALPKIYSHELVQVIFEQPYCRIGNLVERDIAKRQTASVYLKQ 334 + M+Q SE+ T AL + + L+Q+ E IG D S +KQ Sbjct: 93 PIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVD------NSALIKQ 146 Query: 335 LADIGVLEELTIGKEKLFVHPKLMQ 359 + + E L GK +L VHP +Q Sbjct: 147 IQQLLQQEPLFSGKPQLRVHPDDLQ 171
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.8 bits (69), Expect = 0.008 Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%) Query: 248 YFFVSPKRPELAAAILAGLENMISDGSFDEMFNRELKIDKLYRDAQFE 295 Y+F SP++ I +N IS F+E+ +E DKL++ F+ Sbjct: 133 YYFESPEKFAFNKEIRTENQNEISLEKFNEL--KETIQDKLFKQDGFK 178
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 29.7 bits (66), Expect = 0.030 Identities = 13/38 (34%), Positives = 16/38 (42%) Query: 368 DVLTPHYNQVTTYVWERVVDFIKLHYCISDRTDSDFWL 405 DV P VT Y F +L Y + + DFWL Sbjct: 123 DVSFPQSYTVTRYQPRTESSFYRLEYWVGNSNGDDFWL 160
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.4 bits (84), Expect = 1e-05 Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 3 NKLFGFTLVELMVTIAVAAILLTIGVPSLISVYEGVRVNNNIAKI 47 +K GFTL+E+MV I + +L ++ VP+L+ E ++ I Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 61.1 bits (148), Expect = 5e-15 Identities = 25/75 (33%), Positives = 46/75 (61%), Gaps = 2/75 (2%) Query: 2 KKNRLQGFTLIEVMIAVVIVGILASIAYPSYIDYVVKSGRSEGVAAVMKVANLQEQYYLD 61 ++ +GFTL+E+M+ +VI+G+LAS+ P+ + K+ + + V+ ++ + N + Y LD Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 62 NRAYATDMTKLGLAA 76 N Y T T GL + Sbjct: 63 NHHYPT--TNQGLES 75
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.6 bits (74), Expect = 4e-04 Identities = 10/24 (41%), Positives = 18/24 (75%), Gaps = 2/24 (8%) Query: 13 QRGFSLIEVLVALVIL--VIGLIG 34 QRGF+L+E++V +VI+ + L+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVV 30
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.0 bits (65), Expect = 0.019 Identities = 10/36 (27%), Positives = 16/36 (44%), Gaps = 2/36 (5%) Query: 24 RPDFLAYSQELIQVCQRLTPSDIATLMKVSDNIAGL 59 ++E + + + LTPSD A L K + G Sbjct: 147 TGSLATIAEETVIIAEDLTPSDTAQLNK--QFVKGF 180
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 152 bits (384), Expect = 5e-45 Identities = 89/380 (23%), Positives = 147/380 (38%), Gaps = 61/380 (16%) Query: 7 MKNTLK--VVLLTSMLPLAASASQELTPWYVGAGLGVNNYEHIATDNGD----DNPYAWD 60 MK T V L +A +A ++ T WY GA LG + Y N + +N Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNT-WYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 61 IFAGYMFNDYFGAEIGYRDLGSADWTYAGIGNDADVKGATLGLVGVWPLGNRWSLSAEAG 120 F GY N Y G E+GY LG + + +G L +P+ + + G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 121 AMYYTLENNQRVGGVSSSYSENDFAPYFGAGVGYNFTDNLKLQAKYRRYENLDDNAGANA 180 M + + V G + +P F GV Y T + + +Y+ N+ G Sbjct: 120 GMVWRADTKSNVYG---KNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNI----GDAH 172 Query: 181 IVPVNADSNYWGLELSYRFGTAAAAPVAA-AVVAATPVDSDNDGVYDDKDQCPATPATHK 239 + D+ L +SYRFG AAPV A A A V + + + D Sbjct: 173 TIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSD------------ 220 Query: 240 VDSVGCTIYENVKKQEDVGSIQFANDSAVVKKEYYKDIERLANYM--NKNPEFTVEIAGH 297 + F + A +K E +++L + + + +V + G+ Sbjct: 221 --------------------VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGY 260 Query: 298 ASNVGKPEYNMVLSDKRADAVAKILVEKYGISQSRVTSNGYGITKPLVAGDS-------- 349 +G YN LS++RA +V L+ K GI ++++ G G + P V G++ Sbjct: 261 TDRIGSDAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNP-VTGNTCDNVKQRA 318 Query: 350 --KEAHAANRRIEAIVTTTE 367 + A +RR+E V + Sbjct: 319 ALIDCLAPDRRVEIEVKGIK 338
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.007 Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 4/58 (6%) Query: 14 ATSANMALKVSQLSWAIEGKTILSEISFALPQG----EMLGLIGPNGAGKSSLLRCLY 67 T + + + + ++ ++ + G + L G G GKS+L+ L Sbjct: 560 KTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLV 617
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.021 Identities = 14/71 (19%), Positives = 31/71 (43%), Gaps = 5/71 (7%) Query: 354 SGLEPLTIDAQTLFVNVGERTN---VTGSAKFLKLIKEGKFEQALDVAREQVESGAQIID 410 +P+ + + + +TN VT + + ++ + LD+ R QV A I + Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE--RVIAQLDIRRPQVLVEAIIAE 355 Query: 411 INMDEGMLDGV 421 + +G+ G+ Sbjct: 356 VQDADGLNLGI 366
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 31.4 bits (71), Expect = 0.003 Identities = 26/123 (21%), Positives = 40/123 (32%), Gaps = 20/123 (16%) Query: 112 AVDASLERLQIDTIDLY----QVHWPDRNTNFFG--ELFYDEQEIEQQTPILETLEALAE 165 V+ SL + LY + HW + +FF E F E ET++ +AE Sbjct: 12 LVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFE-----ELYDHAAETVDTIAE 66 Query: 166 VIRQGKVRYIGVSNETPWGLMK-YLQLAEKHGLPRIVTVQNPYNLLNRSFEVGMSEISHR 224 + IG P +K Y + A + L ++ SE Sbjct: 67 RLLA-----IGGQ---PVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFV 118 Query: 225 EEL 227 L Sbjct: 119 IGL 121
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 29.5 bits (66), Expect = 0.007 Identities = 9/52 (17%), Positives = 17/52 (32%), Gaps = 2/52 (3%) Query: 65 AADDILRTLEAYGFEWDDTVLYQSART--EAYQAKLDELLAEDNAYFCQCSR 114 I + + GFE Y S E ++ L + + +C + Sbjct: 27 PYSLIKKFMLENGFEHRQYSGYTSKEPINERRVIRIVNKLTKKFTWLGECVK 78
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.8 bits (67), Expect = 0.007 Identities = 7/26 (26%), Positives = 14/26 (53%) Query: 34 HQGHITLVKEAAKKCDHVVVSIFVNP 59 GH+ +++ + D V V++ NP Sbjct: 13 TFGHLDIIERGCRLFDQVYVAVLRNP 38
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 205 bits (524), Expect = 6e-62 Identities = 104/298 (34%), Positives = 140/298 (46%), Gaps = 39/298 (13%) Query: 128 WGMNNTGQNGGTVDADIDAPEAWEITTGSSDVVIGVIDTGVDYNHPDLQANMWVNGGEIP 187 N G + I AP W T G V + V+DTG D +HPDL+A + I Sbjct: 16 EQQVNEIPRGVEM---IQAPAVWNQTRGR-GVKVAVLDTGCDADHPDLKARI------IG 65 Query: 188 GNGIDDDGNGVIDDVHGYSAVNNNGNPMDGNGHGTHVSGTIGAKGNNGVGVVGVNWDVKI 247 G DD G + D NGHGTHV+GTI A N GVVGV + + Sbjct: 66 GRNFTDDDEGDPEI------------FKDYNGHGTHVAGTIAA-TENENGVVGVAPEADL 112 Query: 248 AACQFLDADGYGSTAGAIACLDYFTDLKVNHGVDIKATNNSWGGGSFSQALKDAIEAGGE 307 + L+ G G I + Y + VDI + S GG L +A++ Sbjct: 113 LIIKVLNKQGSGQYDWIIQGIYYA----IEQKVDI--ISMSLGGPEDVPELHEAVKKAVA 166 Query: 308 AGILFVAAAGNDAVDND--ASPHYPSSYDSDVVLSIASTDRNDRMSDFSQWGLTSVDMGA 365 + IL + AAGN+ +D YP Y+ V+S+ + + + S+FS VD+ A Sbjct: 167 SQILVMCAAGNEGDGDDRTDELGYPGCYNE--VISVGAINFDRHASEFSNSN-NEVDLVA 223 Query: 366 PGTAILSTIPGGGYATYSGTSMATPHVTGAAALVWSLNP-----DLSPVEMKTLLMAS 418 PG ILST+PGG YAT+SGTSMATPHV GA AL+ L DL+ E+ L+ Sbjct: 224 PGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKR 281
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 4e-22 Identities = 39/159 (24%), Positives = 65/159 (40%), Gaps = 6/159 (3%) Query: 1 MDKATILVVDDTPENIDILVGILG-EDYKVKVAIDGPRALALVAKTLPDLILLDVMMPGM 59 M ATILV DD +L L Y V++ + +A DL++ DV+MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NGYEVCKLLKQEPLTCHIPVIFVTALSEVADETQGFELGAVDYITKPVSAPVVKARVRTH 119 N +++ +K+ +PV+ ++A + + E GA DY+ KP + + Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LALYDQKRLLEQQVKERTQEL--EETRF-EIIRRLGRAA 155 LA ++ + + L EI R L R Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM 157
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 3e-16 Identities = 34/128 (26%), Positives = 54/128 (42%), Gaps = 5/128 (3%) Query: 1284 ILVADDNATARDIMRTTLESMGFRVDTVRSGEEAVTRCIQQEYAVALIDWKMPNLDGIET 1343 ILVADD+A R ++ L G+ V + + + + D MP+ + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1344 AKQIKQQAKKAPRILMVSAHANQDFLSQIEELGLAGYISKPISASRLLDGIINSLGRAGV 1403 +IK+ P ++M SA + E G Y+ KP L +I +GRA Sbjct: 66 LPRIKKARPDLPVLVM-SAQNTFMTAIKASEKGAYDYLPKPFD----LTELIGIIGRALA 120 Query: 1404 LPVRRQSE 1411 P RR S+ Sbjct: 121 EPKRRPSK 128 Score = 67.5 bits (165), Expect = 2e-13 Identities = 24/103 (23%), Positives = 42/103 (40%), Gaps = 2/103 (1%) Query: 1425 RILLVEDNEMNLEVATEFLEQVGIILSIATNGQIALDKLEQQSFDLVLMDCQMPVMDGYQ 1484 IL+ +D+ V + L + G + I +N + DLV+ D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1485 ATQALRKRPELTELPVVAMTANAMAGDKEMCLRAGMNDHIAKP 1527 ++K +LPV+ M+A G D++ KP Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.4 bits (128), Expect = 3e-12 Identities = 19/64 (29%), Positives = 38/64 (59%) Query: 5 RKGFTLIELMIAVAIIGILAAIAIPSFNEYLKQGRRFDAQQYLVSSAQALERHYSRNGLY 64 ++GFTL+E+M+ + IIG+LA++ +P+ ++ + A +V+ AL+ + N Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 65 PASQ 68 P + Sbjct: 67 PTTN 70
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.1 bits (91), Expect = 1e-06 Identities = 15/31 (48%), Positives = 23/31 (74%) Query: 2 AKRTKAGFTLVELLVAIAIIGILASIALPSY 32 A + GFTL+E++V I IIG+LAS+ +P+ Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNL 33
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.002 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 6/60 (10%) Query: 3 LSAKKQQAGFSLSELMIAMV-LGLIIMLAVVNFF-----APLKATVEESKRLENAADALR 56 + A +Q GF+L E+M+ +V +G++ L V N A + V + LENA D + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.2 bits (57), Expect = 0.025 Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 1 MKKILTLAAIVLAIGGCSGQQADSQTTPV 29 MKK+L AA+ + I GC+ Q P Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPT 34
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 549 bits (1415), Expect = 0.0 Identities = 184/689 (26%), Positives = 300/689 (43%), Gaps = 70/689 (10%) Query: 6 KYRNIGIFAHVDAGKTTTTERILKLTGKIHKLGEVHDGESTTDFMVQEAERGITIQSAAV 65 K NIG+ AHVDAGKTT TE +L +G I +LG V G + TD + E +RGITIQ+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 SCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIAVFCGSGGVEPQSETNWRYANESEV 125 S W++ + N+IDTPGH+DF EVYRSL VLDG I + GV+ Q+ + + + Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 126 ARIIFVNKLDRMGADFLRVVKQTKDVLAANPLVMVLPIGIEDEFTGVVDLLTRKAYVWDD 185 I F+NK+D+ G D V + K+ L+A ++ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ------------------------- 156 Query: 186 SGIPENFTVTDVPADMVDQVEEYREMLIESAVEQDDDLLEAYMEGEEPSIEDLKRCIRKG 245 V P V E + ++ +E +DDLLE YM G+ +L++ Sbjct: 157 -------KVELYPNMCVTNFTESEQ--WDTVIEGNDDLLEKYMSGKSLEALELEQEESIR 207 Query: 246 TRTMAFFPTFCGSAFKNKGMQLVLDAVVDYLPAPDEVDPQPLTDEEGNETGEYAIVSADE 305 + FP + GSA N G+ +++ + + + T +E Sbjct: 208 FHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS--------THRGQSE----------- 248 Query: 306 SLKALAFKI-MDDRFGALTFVRIYAGRLKKGDTILNSATGKTERIGRMCEMYANDRIEIE 364 L FKI ++ L ++R+Y+G L D++ S K +I M + +I+ Sbjct: 249 -LCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKID 306 Query: 365 SAEAGDIIAIVGMKNVQTGHTLCDVKHPCTLEAMVFPEPVISIAVAPKDKGGSEKMAIAI 424 A +G+I+ + + ++ L D K E + P P++ V P E + A+ Sbjct: 307 KAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDAL 365 Query: 425 GKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETIT 484 ++ DP R D + E IL +G++ +++ +L+ Y VE+ + EP V Y E Sbjct: 366 LEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYMERPL 425 Query: 485 QMVEDQYTHKKQSGGSGQFGKIEYIIRPGEPNSGFVFKSSVVGGNVPKEYWPAVEKGFAS 544 + E YT + + + I + P SG ++SSV G + + + AV +G Sbjct: 426 KKAE--YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRY 483 Query: 545 MMNTGTIAGFPVLDVEFELTDGAYHAVDSSAIAFEIAAKAAFRQSIAKAKPQLLEPIMKV 604 G + G+ V D + G Y++ S+ F + A Q + KA +LLEP + Sbjct: 484 GCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF 542 Query: 605 DVFSPEDNVGDVIGDLNRRRGMIKDQVAGVTGVRVKADVPLSEMFGYIGSLRTMTSGRGQ 664 +++P++ + D + I D V + ++P + Y L T+GR Sbjct: 543 KIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSV 602 Query: 665 FSMEFSHYSPC----------PNSVSDKV 683 E Y PNS DKV Sbjct: 603 CLTELKGYHVTTGEPVCQPRRPNSRIDKV 631
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 1e-04 Identities = 24/186 (12%), Positives = 53/186 (28%), Gaps = 5/186 (2%) Query: 74 QPELNQLISQVLSSNNDLTLATLTLQKARLQAGLARDDLYPQLSSNNTASVNKPLDGGSS 133 +P N ++ +++ + L +L A A D SS A + + S Sbjct: 100 KPIENSIVKEIIVKEGESVRKGDVL--LKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 134 SRAFQANL-SVSYEVDLWGKVSANIDQAQWTALAS--LEDRESTAQSLVATTASLYWQIG 190 L + + + + + + + T+L ++ + Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 191 YLHERIELSNKSIEHSRQTLALTQRQYASGAVTELNVLESQRSLAGQEASHSQLLQQLVE 250 + RI + L A+ + VLE + QL + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 251 AENALA 256 E+ + Sbjct: 278 IESEIL 283
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 64.5 bits (157), Expect = 2e-13 Identities = 36/199 (18%), Positives = 67/199 (33%), Gaps = 26/199 (13%) Query: 58 ANGMLQASKLVSVGAQVSGQIQSLPV------DLGQEVKKGDLIAQIDSLAQQNNLQNAL 111 N + ++ ++V A+++ V D + K IA+ L Q+N Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ-AIAKHAVLEQEN----KY 261 Query: 112 ASLKSINAQYRAKQAQIRQAKLEYTRQQEMLADKASSRADFETAEATLTVYQAELEQLQA 171 + Y+++ QI L + +++ F+ +L Q Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV------TQLFKNEILD------KLRQTTD 309 Query: 172 QKQQAEINVDSARIDLGYTKITAPMDGTVVYSAV-EVGQTVNANQTTPTIVEMAQLDTMT 230 + + + I AP+ V V G V +T IV + DT+ Sbjct: 310 NIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV--PEDDTLE 367 Query: 231 VKAQISEADIVNVHPGQAV 249 V A + DI ++ GQ Sbjct: 368 VTALVQNKDIGFINVGQNA 386 Score = 48.3 bits (115), Expect = 3e-08 Identities = 31/182 (17%), Positives = 70/182 (38%), Gaps = 15/182 (8%) Query: 7 MKKSSKRKLILILSGLVLLGGGAYFLLHKPEAAPSYVTEPVKRGDIENSVLANGMLQAS- 65 ++ R+ L+ ++G + S + + +E ANG L S Sbjct: 49 IETPVSRRPRLV--AYFIMGFLVIAFIL------SVLGQ------VEIVATANGKLTHSG 94 Query: 66 KLVSVGAQVSGQIQSLPVDLGQEVKKGDLIAQIDSLAQQNNLQNALASLKSINAQYRAKQ 125 + + + ++ + V G+ V+KGD++ ++ +L + + +SL + Q Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 126 AQIRQAKLEYTRQQEMLADKASSRADFETAEATLTVYQAELEQLQAQKQQAEINVDSARI 185 R +L + ++ + E ++ + + Q QK Q E+N+D R Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 186 DL 187 + Sbjct: 215 ER 216
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 2e-14 Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 8/167 (4%) Query: 1 MSQIKVAIADDHPLFRTALTQAVLKNVNTAEVLEAENFQELITLVENNPDIELIFLDLHM 60 M+ + +ADD RT L QA L +V N L + +L+ D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQA-LSRAG-YDVRITSNAATLWRWIAAGD-GDLVVTDVVM 57 Query: 61 PGNEGFTGLTLLQNHFPDIAVIMVSSDDQPEIIRKAINFGASAFIPKSASLTQISTAIAT 120 P F L ++ PD+ V+++S+ + KA GA ++PK LT++ I Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 121 VLEGEVWLPEHTDINVDQQ-----TAAEHQRLAKQLAQLTPQQYTVL 162 L P + + +A Q + + LA+L T++ Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 39.4 bits (92), Expect = 9e-05 Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 1055 ISVLVIDNDELMLKAISSLLLGWGCHVLTARDKASAEQQLTQQVLPKLIIADYHLDDDQN 1114 ++LV D+D + ++ L G V + A+ + + L++ D + D+ N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-AAGDGDLVVTDVVMPDE-N 61 Query: 1115 GVDLVQSLLTH 1125 DL+ + Sbjct: 62 AFDLLPRIKKA 72
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.024 Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 4/107 (3%) Query: 252 GIVGTIAGILYSRKQPLRLPIIRLSGLLIFLTVLGLSFGTAPWLQTLCAI-VLGFCIFLP 310 I G I GIL R+ PL + I ++ L + T W T+ + VLG F Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK 366 Query: 311 VTALVSIPHELPKMTSQKITVIFSLFWSISYLISTLVLWLFGKLVDI 357 + L Q+ SL S+L + + G L+ I Sbjct: 367 TVISTIVSSSL---KQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature. Length = 234 Score = 25.8 bits (56), Expect = 0.025 Identities = 14/59 (23%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 8 PALKQVQQMLKANQASINGELEELNRQWYALRDNYEGEGAENTEGMVMDLGSWLEEYTN 66 P Q++K +AS N +++L + + D + N+E + LGS + T+ Sbjct: 26 PVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTF-----TNSEVLDNSLGSMRIKNTD 79
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.002 Identities = 37/145 (25%), Positives = 62/145 (42%), Gaps = 17/145 (11%) Query: 30 RTVIRSLILGLLCSGHVLLEGLPGTAKTRSVKAL------ANALAISFGRIQFTPDLLPS 83 + + R L + +++ G GT K +AL N ++ DL+ S Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIES 206 Query: 84 DVTGTE--VLHEAEGKSTLRFQP---GPVFNQIVLADEINRAPAKVQAALLEAMAEGTIT 138 ++ G E A+ +ST RF+ G +F DEI P Q LL + +G T Sbjct: 207 ELFGHEKGAFTGAQTRSTGRFEQAEGGTLF-----LDEIGDMPMDAQTRLLRVLQQGEYT 261 Query: 139 -VAGQTHVLPELFMVLATQNPIEQE 162 V G+T + ++ +V AT ++Q Sbjct: 262 TVGGRTPIRSDVRIVAATNKDLKQS 286
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.8 bits (69), Expect = 0.019 Identities = 58/339 (17%), Positives = 130/339 (38%), Gaps = 26/339 (7%) Query: 340 NQSVEAMQLTMSNFVEQLQKSQAESGDREKALIADISHQVSKLSSQSEDIHQKLTSYVEN 399 ++S A+ T QL+K+QAE R KA +K + + + Q+L V Sbjct: 45 SESSAAIHATAKWSTAQLKKTQAEQAARAKAAAE----AQAKAKANRDALTQRLKDIVNE 100 Query: 400 QIGKISSQMQIREEASAKRDSELVNVIGQQVNELVNNSRRQGELLTSFVETQLNNLTKSF 459 + +S+ SA + N Q +E + + + E E ++ Sbjct: 101 ALRHNASR-----TPSATELAHANNAAMQAEDERLRLA-KAEEKARKEAEAAEKAFQEAE 154 Query: 460 DERDKRSTELETTRNN----KIEKQTEAIVKISNELISTVEKSVSEQLAAVKHLVSQGET 515 R + E T + E++ A + + + +K +S + V + + +T Sbjct: 155 QRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKT 214 Query: 516 LQNSVNASVEAAAQATQAMKESSIELRVSADHMRVLSSHVNDAGNKLSGAIKSAVDSTAD 575 L + +++S+ A + + EL ++ + L V + + +++ Sbjct: 215 LNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFE-- 272 Query: 576 LANQNQISAQRI-ENARESLMKDVSRFSELSDQIKALITSASSTFTELKSTQRDFIGNLK 634 A + ++ A +I E ++ + +R ++I A IT +++ + + I + Sbjct: 273 -ATRRRVGAGKIREEKQKQVTASETRI----NRINADITQIQKAISQVSNNRNAGIARVH 327 Query: 635 EEVESLSRKMTDMLEEYSQQANGQTAEHLKIWSQSVTDY 673 E E+L + ++L + A T Q++T+ Sbjct: 328 EAEENLKKAQNNLLNSQIKDAVDATVSFY----QTLTEK 362
>PF07472#Fucose-binding lectin II Length = 245 Score = 30.8 bits (69), Expect = 0.027 Identities = 19/81 (23%), Positives = 44/81 (54%), Gaps = 10/81 (12%) Query: 683 QSFRHTYISPILQAAGDEIESVRASLGRKLREKVGALMLRRVKEDNLERLPKKNMFVGLE 742 Q F H + +LQ AG++ +V+A+ + + +++ M ++ +E+LP+ ++FV + Sbjct: 3 QPFTHDDLYALLQLAGNDATAVQANGDQAVLDRMRQFMTTQL----VEKLPQYDVFVDIA 58 Query: 743 PTEWQYEPKLHSIMDSYQQKV 763 + ++ + S+Q KV Sbjct: 59 TIPYSFD------VGSWQNKV 73
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.2 bits (63), Expect = 0.041 Identities = 22/96 (22%), Positives = 43/96 (44%), Gaps = 22/96 (22%) Query: 70 RPAVQLTQEGLDAISELQQTPKGNLRISVPMVFGRLYIAPLIAEFLKRYPDIQLQMQMDD 129 + + TQ L A+ L+ + GNL++ PM+ + E Q + M + Sbjct: 367 KQDIFRTQ--LRAL--LRASTYGNLKVMFPMI-------ATLEEL------RQAKAIMQE 409 Query: 130 KTTDLIAGGFDLA--IRIG---ELPDSSLIARKIAP 160 + L++ G D++ I +G E+P +++ A A Sbjct: 410 EKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAK 445
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.029 Identities = 17/125 (13%), Positives = 46/125 (36%), Gaps = 12/125 (9%) Query: 107 YWPALITLFLAMLDMVVRLNLHKNALWFQAEFFKHRQDIDLSHWSLA----LPLLLFIQT 162 +W L+ + + + V L + + + + D+ L + +LF + Sbjct: 167 HWSYLLLIPMITIITVPFL------MKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS 220 Query: 163 ATY-FFALWRLFQRHKLRQQQRNEAPQQTLKLIRFR-WLFGLTLAMLFNWLLRVFVVVLP 220 + F + L ++ ++ P L + ++ G+ + + FV ++P Sbjct: 221 YSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVP 280 Query: 221 FYLGD 225 + + D Sbjct: 281 YMMKD 285
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 6e-08 Identities = 19/117 (16%), Positives = 47/117 (40%), Gaps = 15/117 (12%) Query: 59 VSSVKEAVLAFEVPGKVIKLHVKEGDFVKQDTVLAEIDDRDYQAQLDSAKSDLIVAKSDF 118 S + + E V ++ VKEG+ V++ VL ++ +A +S L+ A+ + Sbjct: 92 HSGRSKEIKPIE-NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150 Query: 119 QRYE---KALKADAVTPQAF-----------QQAKRNLEVAQAAFNQADKALTETKL 161 RY+ ++++ + + ++ R + + F+ + +L Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKEL 207 Score = 42.5 bits (100), Expect = 2e-06 Identities = 37/190 (19%), Positives = 74/190 (38%), Gaps = 29/190 (15%) Query: 100 YQAQLDSAKSDLIVAKSDFQRYEKALKADAVTPQAFQQAKRNLEVAQAAFNQADKALTET 159 Y++QL+ +S+++ AK ++Q + K + + Q N+ + + ++ + Sbjct: 271 YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR--QTTDNIGLLTLELAKNEERQQAS 328 Query: 160 KLIAPFAGRVVTREI-DLFATVHAKQPIMQL-HSESAYEMVVSVPESDWAQGERVNSAAD 217 + AP + +V ++ V + +M + + E+ V D V A Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGF-INVGQNAI 387 Query: 218 IKLDNQLFVTLTAFPDKRF---EGKITEFSGQADAAT--RT---YKVKVAFSVP------ 263 IK++ AFP R+ GK+ + DA R + V ++ Sbjct: 388 IKVE--------AFPYTRYGYLVGKVKNIN--LDAIEDQRLGLVFNVIISIEENCLSTGN 437 Query: 264 DKTPISSGMT 273 P+SSGM Sbjct: 438 KNIPLSSGMA 447
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 459 bits (1182), Expect = e-147 Identities = 220/1050 (20%), Positives = 445/1050 (42%), Gaps = 67/1050 (6%) Query: 3 IASVAINNRVVTLVLTVVMLIAGLYIFNGMSRLEDPEFTIKDALIITPYNGASALEVEQE 62 +A+ I + VL +++++AG + + P + Y GA A V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTELLEKTVQQLGELDKVTSKSER-GLSTITVTIKEQYNKETLPQVWNKLRQKIDDVKYY 121 VT+++E+ + + L ++S S+ G TIT+T + + + +++ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPD---IAQVQVQNKLQLATPL 117 Query: 122 LPPGA-GPSLVIDDYGDVYSIFMVV----SGDGYSFKELKTYVND-LQQQLLLVNGVGKI 175 LP + ++ S MV G + ++ YV ++ L +NGVG + Sbjct: 118 LPQEVQQQGISVEKSSS--SYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV 175 Query: 176 TTFGEKSEAIYIEFNRSRMAQLGISPEIVAAQLNGKGLVVDAGRAHVGSS------SIAV 229 FG + A+ I + + + ++P V QL + + AG+ + + ++ Sbjct: 176 QLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASI 234 Query: 230 STTGGFTKVSDFEKLLI--THDTKQFYLSDIAKVSRGYVSPSTQLINFDGKAGIGLGIST 287 F +F K+ + D L D+A+V G + +GK GLGI Sbjct: 235 IAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELG-GENYNVIARINGKPAAGLGIKL 293 Query: 288 VSGGNTVDMGEAVLAKLSELESQRPAGIEFGYVSLQSEGVKEAISGFTSSLAEAVIIVIV 347 +G N +D +A+ AKL+EL+ P G++ Y + V+ +I +L EA+++V + Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 348 VLLFFMG-LRSGLLIGFVLILTIAGSFIFLAPMGVALERISLGALIIALGMLVDNAIVVV 406 V+ F+ +R+ L+ + + + G+F LA G ++ +++ +++A+G+LVD+AIVVV Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 407 DGILIRMQK-GESAESAAPRVVNQSAWPLLGATLIAILAFAAIGTSNDATGEYCRSLFQV 465 + + M + + A + ++Q L+G ++ F + +TG R Sbjct: 414 ENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSIT 473 Query: 466 VMVSLLLSWVTAVTITPLLCVMYLKAPKSTDKTSPYQGTFYT-----------KYRGLLA 514 ++ ++ LS + A+ +TP LC LK + + G F+ Y + Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENK--GGFFGWFNTTFDHSVNHYTNSVG 531 Query: 515 SSIRHRYLSSASIIGIFALSLWGFSFVQQNFFPSSTRAQFMVDFWLPQGTHIEETQKHAE 574 + I A + F + +F P + F+ LP G E TQK + Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 575 SVENYLGNL--ANVEHVTTTIGEGALRFLLTYQPQQSNSSYAQF-LVDVDDYTVIKTLIP 631 V +Y ANVE V T G ++ Q N+ A L ++ + Sbjct: 592 QVTDYYLKNEKANVESVFTVNG-------FSFSGQAQNAGMAFVSLKPWEERNGDENSAE 644 Query: 632 KIEVELLQKY---PDALVYASP----FELGTGTAGKIQ-ARISGPDTDVLRETSDKVLEV 683 + + D V ELGT T + +G D L + +++L + Sbjct: 645 AVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 684 FSKE-SNTKGVRTDWRNKQLYIEAVLAEEQANINGINRGMVAEAIKESFEGVTTGVYREN 742 ++ ++ VR + + + +E+A G++ + + I + G + + Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 743 DLLLPIIIRANENERSDITNIENVQIWSPNAQKMIPLRQVVQSFETKFEDGLILRRNRER 802 + + ++A+ R +++ + + S N + M+P + + + R N Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGE-MVPFSAFT-TSHWVYGSPRLERYNGLP 822 Query: 803 TITIFADPVTG-TASELLATLKPQVEAIKIPPGYTLEWGGEYEDSSKAEKGLASSIPIFI 861 ++ I + G ++ + +A ++ K+P G +W G + + + I Sbjct: 823 SMEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880 Query: 862 LSMILITIVIFNSLKQTLVIWLCVPLALIGVTAGMLATNQPFGFMALLGFLSLIGMLIKN 921 + + L ++ S + + L VPL ++GV NQ ++G L+ IG+ KN Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 922 AIVLVDEIN-LEQSQGKSLINSILDSGVSRLRPVAMAALTTALGMIPLIFD-----AFFV 975 AI++V+ L + +GK ++ + L + RLRP+ M +L LG++PL Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 976 SMAVTIISGLMFATALTMIVLPIVYALIFK 1005 ++ + ++ G++ AT L + +P+ + +I + Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.6 bits (157), Expect = 4e-15 Identities = 30/184 (16%), Positives = 72/184 (39%), Gaps = 9/184 (4%) Query: 19 DEKRNELLCTAINLLVTDGYAGLSMRNLASKAQVTTGAITYYFSNKSELMKGVSDELFNR 78 E R +L A+ L G + S+ +A A VT GAI ++F +KS+L + + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 79 FSLLLA-------KNTEIDIKQAVEEWINWTYSDGGE-IWKAFLQVQFYAAEDKTFIDYA 130 L + +++ + + T ++ + + + + + A Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 131 QKRYDI-FISQLKHFIESGQKSKQIRNDIPAEILAEQLSAMGDGMMIMQSIYPERLSIEK 189 Q+ + +++ ++ ++K + D+ A + G+M P+ ++K Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 190 IAQF 193 A+ Sbjct: 190 EARD 193
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.5 bits (63), Expect = 0.021 Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 7/86 (8%) Query: 118 RLKRLEKRALVRGETFNPIKNIQPREFYTFHRIAISSGSNKQDYLLHIQKMVAK----EQ 173 + LEK +R +T NI F R+ + +GSN + L IQ+ A+ + Sbjct: 467 QFLELEKTKQLRLDTDQVYGNIATYNFEN-GRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 174 TEPLFSSYGVASNLQ--LNGTVPELS 197 L A N L T P+++ Sbjct: 526 DLNLVERRIAAVNPSDPLETTKPDMT 551
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 65.1 bits (158), Expect = 5e-13 Identities = 31/162 (19%), Positives = 59/162 (36%), Gaps = 10/162 (6%) Query: 99 QAAEAARLAAEQAEAQRIAEEQAARLAEQQAVEAARLAAEQAQAEQLAAEKAEAERIAAE 158 QA+ + +A A ++ + AE ++ E E Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 159 QAAKAQAEAQRVAEEQAVRLAEQQAVEAARLAAEQAQAEQLAAEKAEAERIAAEQAAAAQ 218 + + E E A + V+A E AQ+ E E + ++ A + Sbjct: 1053 KNEQDATETTAQNREVA--KEAKSNVKANTQTNEVAQSGS---ETKETQTTETKETATVE 1107 Query: 219 AEAEAQAEAERIA-----AAQIQAEQPLEQQPEPQAKPAKES 255 E +A+ E E+ +Q+ +Q + +PQA+PA+E+ Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149 Score = 61.2 bits (148), Expect = 8e-12 Identities = 32/187 (17%), Positives = 61/187 (32%), Gaps = 13/187 (6%) Query: 74 AEQAAKAQAEAQRVAEEQAASLAEQQAAEAARLAAEQAEAQRIAEEQAARLAEQQAVEAA 133 QA+ V +A A +E E + + E + VE Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ--ESKTVEKN 1054 Query: 134 RLAAEQAQAEQ-LAAEKAEAERIAAEQAAKAQAEAQRVAEEQAVRLAEQQAVEAARLAAE 192 A + A+ A++A++ A Q + E Q E VE + Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE------K 1108 Query: 193 QAQAEQLAAEKAEAERIAAE----QAAAAQAEAEAQAEAERIAAAQIQAEQPLEQQPEPQ 248 + +A+ + E ++ ++ Q + + +A+ E I+ Q Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 249 AKPAKES 255 +PAKE+ Sbjct: 1169 EQPAKET 1175 Score = 60.8 bits (147), Expect = 1e-11 Identities = 37/232 (15%), Positives = 75/232 (32%), Gaps = 33/232 (14%) Query: 17 DEVVEQTPVSTPSQTEQAEALAKQQAEEARLAAEKAAAEQALADKLAAEKAEAERIAAEQ 76 ++ V+ T ++TP+ + A + + E + A +E AE Sbjct: 989 NQTVDTTNITTPNNIQ-----ADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 77 AAKAQAEAQRVAEEQAASLAEQQAAEAARLAAEQAEAQRIAEEQAARLAEQQAVEAARLA 136 + + E + EQ A E E A+ + V+A Sbjct: 1044 SKQ---------ESKTVEKNEQDATETTAQNREVAKE------------AKSNVKANTQT 1082 Query: 137 AEQAQAEQLAAEKAEAERIAAEQAAKAQAEAQRVAEEQAVRLAEQQAVEAARLAAEQAQA 196 E AQ+ E E + ++ A E + A+ + + E V ++++ +Q Q+ Sbjct: 1083 NEVAQSGS---ETKETQTTETKE--TATVEKEEKAKVETEKTQEVPKV-TSQVSPKQEQS 1136 Query: 197 EQ-LAAEKAEAERIAAEQAAAAQAEAEAQAEAERIAAAQIQAEQPLEQQPEP 247 E + E Q++ A+ E+ A + + Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTT 1188
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 5e-18 Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 1/124 (0%) Query: 3 VLLVEDNRLLSNNIIQYLELSGIECDYAFNLAQADMLISQQQFDVVILDLNLPDGDGIKA 62 +L+ +D+ + + Q L +G + N A I+ D+V+ D+ +PD + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 63 CERWKAQCITSPIIMLTARSSLRERLDGFAVGADDYLVKPFAMEELVARL-KVVAQRRPA 121 R K P+++++A+++ + GA DYL KPF + EL+ + + +A+ + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 122 PQRL 125 P +L Sbjct: 126 PSKL 129
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 226 bits (578), Expect = 2e-79 Identities = 80/155 (51%), Positives = 113/155 (72%) Query: 5 AIYPGTFDPITNGHADLIERAAKLFKHVIIGIAANPSKQPRFTLEERVELVNRVTAHLDN 64 AIYPG+FDPIT GH D+IER +LF V + + NP+KQP F+++ER+E + + AHL N Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPN 62 Query: 65 VEVVGFSGLLVDFAKEQRASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEEN 124 +V F GL V++A++++A ++RGLR +SDFE E Q+AN N+ L+ DLE+VFLT + E Sbjct: 63 AQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEY 122 Query: 125 SFISSTLVKEVALHGGDVSQFVHPEVASALTAKLN 159 SF+SS+LVKEVA GG+V FV VA+AL + + Sbjct: 123 SFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQFH 157
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 182 bits (462), Expect = 5e-58 Identities = 72/295 (24%), Positives = 138/295 (46%), Gaps = 33/295 (11%) Query: 8 IAKAAGIPHKPLSQVVFWFGFILSLLLAAQITWKLVPSTSSPTAWSPTAVTTTGKGAGQV 67 I+K + + +++F+ +L A I W++ ++P + +V T A Q Sbjct: 3 ISKLPPLSPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVS----SVQITPAQARQQ 58 Query: 68 DLAGLQQLALFGRADAKSDKPKVEVVETVTDAPKTSLSIQLTGVVASTADQKGLAIIESS 127 + L LFG + K+ ++ +++ P ++L++ LTGV+A D + +AII Sbjct: 59 PV-TLNDFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKD 116 Query: 128 GSQETYSLGDKIKGTSASLKEVYADRIIITNAGRYETLMLDGLVYTSQSPANQQLQKAKS 187 Q + + +++ G +A + + DR+++ GRYE L L + Sbjct: 117 NEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPG------- 169 Query: 188 EKAEVVSRVDQRKNTEISQELAESRSELLADPSKITDYIAISPVRQGESVVGYRLNPGKD 247 A+V ++ QR + ++DY++ SP+ + GYRLNPG Sbjct: 170 --AQVNEQLQQR------------------ASTTMSDYVSFSPIMNDNKLQGYRLNPGPK 209 Query: 248 VNLFKQAGFKPNDLAKSINGYDLTVMSQALEMMSQLPELTEVSIMVEREGQLVEI 302 + F + G + ND+A ++NG DL QA + M ++ ++ ++ VER+GQ +I Sbjct: 210 SDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDI 264
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 594 bits (1534), Expect = 0.0 Identities = 327/681 (48%), Positives = 444/681 (65%), Gaps = 35/681 (5%) Query: 6 IRRKLIAGVVAGATMLTSQFVWSEQYAANFKGTDIQEFINIVGKNLNKTIIVDPTIRGKI 65 IR + ++ A + +E+++A+FKGTDIQEFIN V KNLNKT+I+DP++RG I Sbjct: 7 IRSFSLTLLIFAALLFRP--AAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTI 64 Query: 66 NVRSYDLLNDEQYYQFFLNVLQVYGYAIVEMENNVIKVIKDKDAKTAAIRVANDNDPGLG 125 VRSYD+LN+EQYYQFFL+VL VYG+A++ M N V+KV++ KDAKTAA+ VA+D PG+G Sbjct: 65 TVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG 124 Query: 126 DEMVTRIVALYNTEAKQLAPLLRQLNDNAGGGNVVNYDPSNVLMLSGRAAVVNKLVEIVR 185 DE+VTR+V L N A+ LAPLLRQLNDNAG G+VV+Y+PSNVL+++GRAAV+ +L+ IV Sbjct: 125 DEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVE 184 Query: 186 RVDKQGDTSVQVVPLEYASAGEMVRIIDTLYRATANQAQLPGQAPKVVADERINAVVVSG 245 RVD GD SV VPL +ASA ++V+++ L + T+ A VVADER NAV+VSG Sbjct: 185 RVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSG 244 Query: 246 DEKSRQRVVELIHRLDAEQASTGNTKVRYLRYAKAEDLVEVLTGFAQKLEGEKDPSAQAG 305 + SRQR++ +I +LD +QA+ GNTKV YL+YAKA DLVEVLTG + ++ EK + Sbjct: 245 EPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVA 304 Query: 306 GKRRNEINIMAHTDTNALVISAEPDQMRTIESVINQLDIRRAQVLVEAIIVEVAEGDNVG 365 +N I I AH TNAL+++A PD M +E VI QLDIRR QVLVEAII EV + D + Sbjct: 305 ALDKN-IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLN 363 Query: 366 FGVQWAAKADGGTQFNNLGPTIGEIGAGIWQAQDKEGTYITNPSTGEVIGKNPDTKGDVT 425 G+QWA K G TQF N G I AG + G V+ Sbjct: 364 LGIQWANKNAGMTQFTNSGLPISTAIAG---------------------ANQYNKDGTVS 402 Query: 426 -LLAQALGKVNGMAWGVAMGDFGALVQAVSADTNSNVLATPSITTLDNQEASFIVGDEVP 484 LA AL NG+A G G++ L+ A+S+ T +++LATPSI TLDN EA+F VG EVP Sbjct: 403 SSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVP 462 Query: 485 ILTGSTASSNNSNPFQTVERKEVGVKLKVVPQINEGNAVKLAIEQEVSGVNG-----NTG 539 +LTGS +++ N F TVERK VG+KLKV PQINEG++V L IEQEVS V ++ Sbjct: 463 VLTGSQ-TTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSD 521 Query: 540 VDISFATRRLTTTVMADSGQIVVLGGLINEEVQESVQKVPFLGDIPVLGHLFKSSSSKKT 599 + +F TR + V+ SG+ VV+GGL+++ V ++ KVP LGDIPV+G LF+S+S K + Sbjct: 522 LGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVS 581 Query: 600 KKNLMIFIKPTIIRDGVTMEGIAGRKYNYFRALQLEQ--QERGVNLMPNTQVPILEEWNQ 657 K+NLM+FI+PT+IRD + +Y F Q +Q +E ++ + I Q Sbjct: 582 KRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYP--RQ 639 Query: 658 SEYLPPEVNDILDRYKEGKGL 678 +V+ +D + G L Sbjct: 640 DTAAFRQVSAAIDAFNLGGNL 660
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 508 bits (1309), Expect = 0.0 Identities = 231/407 (56%), Positives = 307/407 (75%), Gaps = 1/407 (0%) Query: 1 MPAFEYKALDAKGKQLKGVIEADTARHARSQLRDQRMMPLEILPVTEKEAKSKGTGFS-P 59 M + Y+ALDA+GK+ +G EAD+AR AR LR++ ++PL + + KS TG S Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 FKRGISVAELALITRQIATLVAAGLPIEECLKAVGQQCEKARLASMIMAVRSRVVEGYSL 119 K +S ++LAL+TRQ+ATLVAA +P+EE L AV +Q EK L+ ++ AVRS+V+EG+SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 ADSLAEFPHIFDDLYRAMVASGEKSGHLEVVLNRLADYTERRQQLKSKLQQAMIYPIMLT 179 AD++ FP F+ LY AMVA+GE SGHL+ VLNRLADYTE+RQQ++S++QQAMIYP +LT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 IVAIGVVSVLLAAVVPKVVGQFEHMGAELPATTRFLIAASDFVQHYGLFVILAIGILLVV 239 +VAI VVS+LL+ VVPKVV QF HM LP +TR L+ SD V+ +G +++LA+ + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 FQRLLKSPIFKMKYHTFLLKMPVIGRVSKGLNTARFARTLSILSASSVPLLDGMRIASEV 299 F+ +L+ ++ +H LL +P+IGR+++GLNTAR+ARTLSIL+AS+VPLL MRI+ +V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 LQNVRVRAAVDDATARVREGTSLGAALTNTKLFPAMMLYMIASGEKSGQLEEMLERAADN 359 + N R + AT VREG SL AL T LFP MM +MIASGE+SG+L+ MLERAADN Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QDREFESNVTLALGVFEPMLVVSMAGVVLFIVMAILQPILALNNLIS 406 QDREF S +TLALG+FEP+LVVSMA VVLFIV+AILQPIL LN L+S Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 231 bits (591), Expect = 7e-82 Identities = 98/144 (68%), Positives = 119/144 (82%) Query: 1 MQMNKKHKGFTLLEVMVVIVILGILASMVVPNLMGNKDKADQQKAVSDIVALENALDMYK 60 M+ K +GFTLLE+MVVIVI+G+LAS+VVPNLMGNK+KAD+QKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNGVYPTTEQGLEALVQKPTISPEPRNYREEGYVKRLPQDPWRNNYLLLSPGENSKLDI 120 LDN YPTT QGLE+LV+ PT+ P NY +EGY+KRLP DPW N+Y+L++PGE+ D+ Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 FSAGPDGQPGTEDDIGNWNLQNFQ 144 SAGPDG+ GTEDDI NW L + Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 86.2 bits (213), Expect = 1e-23 Identities = 43/171 (25%), Positives = 70/171 (40%), Gaps = 39/171 (22%) Query: 4 LRHAGFTLMEVMLVILLMGLTAAAVTMSIGNSGSQQALEKNAQQFIAATELVLDETVLSG 63 +R GFTL+E+ML++LLMG++A V ++ S A + +F A V + +G Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQT-LARFEAQLRFVQQRGLQTG 59 Query: 64 QFIGIVVEKTSYQFVYYKDG---------------KWNPLEKDRILSEKQMEPGVVLNLV 108 QF G+ V +QF+ + +W PL R+ + Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGS---------- 109 Query: 109 LDGLPLVQEDEKDESWFDEPLIEPSAEDKKKHPEPQILLFPSGEMSAFELS 159 + G L + E+W P +L+FP GEM+ F L+ Sbjct: 110 IAGGKLNLAFAQGEAW-------------TPGDNPDVLIFPGGEMTPFRLT 147
>PilS_PF08805#PilS N terminal Length = 185 Score = 30.7 bits (69), Expect = 9e-04 Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 5 KGMTLLEVIVALAVFAIAAVSITKSLGEQMAN 36 KG TL+EV++ + V + A S K +N Sbjct: 26 KGATLMEVLLVVGVIVVLAASAYKLYSMVQSN 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 0.002 Identities = 14/41 (34%), Positives = 26/41 (63%), Gaps = 3/41 (7%) Query: 3 LKQTKAHKGFTLLEMLIAIAIFAMLGLAANAVLSTVLTNDE 43 ++ T +GFTLLE+++ I I +G+ A+ V+ ++ N E Sbjct: 1 MRATDKQRGFTLLEIMVVIVI---IGVLASLVVPNLMGNKE 38
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 91.3 bits (226), Expect = 4e-24 Identities = 71/257 (27%), Positives = 114/257 (44%), Gaps = 16/257 (6%) Query: 6 IALITGASRGLGKNAALTLAAQGVDIILTYQSNAAAAAEVVAEIEWHGRKAVALPLDVGD 65 IA ITGA++G+G+ A TLA+QG I N +VV+ ++ R A A P DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 66 SQSFSDFSLRVKAALEQTWLRDSFNYLVNNAGIGIHVPMAETSVEQFDTLMNIHVKGPFF 125 S + + + R++ + + LVN AG+ + S E+++ +++ G F Sbjct: 69 SAAIDEITARIEREMGP------IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 126 LTQALLPLLAD--NGSIINVSTGLTRFAVPGFGAYAIMKGAVETMTKYWAKELGPRGIRV 183 ++++ + D +GSI+ V + AYA K A TK EL IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NVLAPGAIETDFGGGAVRDNPKMNEFLAQQTA-------LGRVGLPEDIGGAISVLLSPA 236 N+++PG+ ETD D + + L ++ P DI A+ L+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 237 AAWINAQRIEASGGMFL 253 A I + GG L Sbjct: 243 AGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 341 bits (876), Expect = e-113 Identities = 120/375 (32%), Positives = 200/375 (53%), Gaps = 17/375 (4%) Query: 268 FHRDSALHVQTQALALTQTKSTRTLQDKPLNQLGVRFRDPLLERAWQQANKVITKQIPLL 327 F + + +ALA + + ++ D + R ++ ++ +++ + L+ Sbjct: 106 FDLTELIGIIGRALAEPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLM 164 Query: 328 VLGETGVGKEQFVKKLHAQSTRRAQPIVAVNCAALPAELVESELFGYQAGAFTGANRTGF 387 + GE+G GKE + LH RR P VA+N AA+P +L+ESELFG++ GAFTGA Sbjct: 165 ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRS- 223 Query: 388 IGKIRQAHGGFLFLDEIGEMPLAAQSRLLRVLQEREVVPVGSNQSFKVDIQIIAATHMDL 447 G+ QA GG LFLDEIG+MP+ AQ+RLLRVLQ+ E VG + D++I+AAT+ DL Sbjct: 224 TGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDL 283 Query: 448 ESLVAQGLFRQDLFYRLNGLQVRLPALRERQ-DIERIIH---KLHRRHRSSAQTLCTELL 503 + + QGLFR+DL+YRLN + +RLP LR+R DI ++ + + + E L Sbjct: 284 KQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEAL 343 Query: 504 AQLMRYDWPGNLRELDNLMQVACLMAEGEAVLEINHLPDYLAQKLMNLACEPQTLTEVAD 563 + + WPGN+REL+NL++ + + V+ + + L ++ + E + Sbjct: 344 ELMKAHPWPGNVRELENLVRRLTALYPQD-VITREIIENELRSEIPDSPIEKAAARSGSL 402 Query: 564 AEATAHPHELVESSSVTIDSLHGTINLN----------VLQAYRACDGNVSQCAKRLGIS 613 + + A + + + D+L + + +L A A GN + A LG++ Sbjct: 403 SISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLN 462 Query: 614 RNALYRKLKQLGIKD 628 RN L +K+++LG+ Sbjct: 463 RNTLRKKIRELGVSV 477
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 25/121 (20%), Positives = 51/121 (42%), Gaps = 12/121 (9%) Query: 274 IAYEAEQLEKLIAELLELSRVKLSTNETKVRLGLAESLSQVLDDAEFEADQQGKKIT--I 331 I + + +++ L EL R L + + + LA+ L+ V + + Q ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQ-VSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 332 DIDEAIELSHYPKSLSRAIENLLRNAIRYA------QSDIHLLASQANGQVQITIKDDGP 385 I+ AI P L ++ L+ N I++ I L ++ NG V + +++ G Sbjct: 245 QINPAIMDVQVPPML---VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 386 G 386 Sbjct: 302 L 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 2e-25 Identities = 46/163 (28%), Positives = 77/163 (47%), Gaps = 3/163 (1%) Query: 2 SRILLIDDDLGLSELLGQLLELEGFKLTLAYDGKQGLELALAGDYDLILLDVMLPKLNGF 61 + IL+ DDD + +L Q L G+ + + + AGD DL++ DV++P N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVLRALRQH-KQTPVLMLTARGDEIDRVVGLEIGADDYLPKPFNDRELIARIRAIIRRSH 120 ++L +++ PVL+++A+ + + E GA DYLPKPF+ ELI I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 LTAQEIHATPAQEFGDLRLDPSRQEAYCNEQLIILTGTEFTLL 163 ++ + + QE Y L L T+ TL+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIY--RVLARLMQTDLTLM 164
>PF01206#SirA family protein Length = 76 Score = 27.4 bits (61), Expect = 0.007 Identities = 5/35 (14%), Positives = 14/35 (40%) Query: 90 PLLMWRSRVTCEQSGKVVIIECLDERKRRSIIRWC 124 P+L + + +G+V+ + D + + Sbjct: 18 PILKAKKTLATMNAGEVLYVMATDPGSVKDFESFS 52
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 57.2 bits (138), Expect = 1e-12 Identities = 27/122 (22%), Positives = 40/122 (32%), Gaps = 12/122 (9%) Query: 1 MKKLSLVAVSLLSALVAGQASAAADTTGFYVGGAL-------NRVAVDVVDDSDTGTGFG 53 MKK +A+++ A A A AA +Y G L + + G G Sbjct: 1 MKKT-AIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 54 VYGGYNFNEWFGLEANLF----ATADLGDRDTDVTAGALTFTPKFTLQINDMFSAYAKVG 109 +GGY N + G E + A + T K I D Y ++G Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 110 VA 111 Sbjct: 120 GM 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 557 bits (1438), Expect = 0.0 Identities = 198/474 (41%), Positives = 294/474 (62%), Gaps = 12/474 (2%) Query: 5 VWILDDDSSIRWVLEKALQGAKLSTASFAAAESLWQALEISQPRVIVSDIRMPGTDGLTL 64 + + DDD++IR VL +AL A + A +LW+ + ++V+D+ MP + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 65 LERLQIHYPHIPVIIMTAHSDLDSAVSAYQAGAFEYLPKPFDIDEAISLVERALTHATEQ 124 L R++ P +PV++M+A + +A+ A + GA++YLPKPFD+ E I ++ RAL + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE--PK 123 Query: 125 SPAPAAQETQVKTPEIIGEAPAMQEVFRAIGRLSRSSISVLINGQSGTGKELVAGALHKH 184 ++ ++G + AMQE++R + RL ++ ++++I G+SGTGKELVA ALH + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 185 SPRKDKPFIALNMAAIPKDLIESELFGHEKGAFTGAANVRQGRFEQANGGTLFLDEIGDM 244 R++ PF+A+NMAAIP+DLIESELFGHEKGAFTGA GRFEQA GGTLFLDEIGDM Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 245 PLDVQTRLLRVLADGQFYRVGGHSAVQVDVRIIAATHQDLEQLVLKGGFREDLFHRLNVI 304 P+D QTRLLRVL G++ VGG + ++ DVRI+AAT++DL+Q + +G FREDL++RLNV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 305 RVHLPPLSQRREDIPQLATHFLASAAKEIGVEAKILTKETAAKLSQLPWPGNVRQLENTC 364 + LPPL R EDIP L HF+ A KE G++ K +E + PWPGNVR+LEN Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 365 RWLTVMASGQEILPQDLPQELLKEPASINPMAKGSQDWQSALTEWIDQKLSE-------- 416 R LT + I + + EL E ++ ++++ +++ + + Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 417 -GNSDLLTEVQPAFERILLETALRHTQGHKQEAAKRLGWGRNTLTRKLKELSMD 469 S L V E L+ AL T+G++ +AA LG RNTL +K++EL + Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 6e-06 Identities = 35/187 (18%), Positives = 72/187 (38%), Gaps = 33/187 (17%) Query: 167 LIIEQADRLRSLVDRL-------LGPQRPTQHSLHNIHQVVQKVYKLVEMALPANIQLKR 219 LI+E + R ++ L L Q SL + VV +L + +Q + Sbjct: 185 LILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFEN 244 Query: 220 DYDPSIPDIEMDPDQMQQAVLNILQNAVQALEHTGGEILIRTRTQHQVTIGSQRHKLVLT 279 +P+I D+++ P +Q V N +++ + L GG+IL++ + +T Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQ-GGKILLKGTKDNGT----------VT 293 Query: 280 LSIIDNGPGIPPELMDTLFYPMVTSREQGSGLGLSIAHNIARLHSG---RIDCVSSPGHT 336 L + + G + + ++ +G GL ++ G +I G Sbjct: 294 LEVENTGSL------------ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341 Query: 337 EFIISLP 343 ++ +P Sbjct: 342 NAMVLIP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 2e-13 Identities = 25/77 (32%), Positives = 33/77 (42%) Query: 1 MKTETQSTRQHILDVGYSLILKQGFSCLGLAQLLKAAQVPKGSFYHYFKSKEQFGEALLA 60 K E Q TRQHILDV L +QG S L ++ KAA V +G+ Y +FK K + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 GYFEQYQAELDSLLNET 77 + Sbjct: 65 LSESNIGELELEYQAKF 81
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 787 bits (2033), Expect = 0.0 Identities = 322/1038 (31%), Positives = 538/1038 (51%), Gaps = 36/1038 (3%) Query: 5 DIFIRRPVLAASISFLLLLLGFNALNSMQVREYPKMTNTVVTVSTSYYGADANLIQGFIT 64 + FIRRP+ A ++ +L++ G A+ + V +YP + V+VS +Y GADA +Q +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPLEQALAQADNVDFMTSESF-LGTSKISVYMKLNTDPNGALADILAKVNSVRSQLPKEA 123 Q +EQ + DN+ +M+S S G+ I++ + TDP+ A + K+ LP+E Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 EDPSVEMSTGSQTSVLYISFFSDQINSSQ--LTDYLERVVKPQLFTIDGVAKVNLYGGIK 181 + + + S + ++ F SD ++Q ++DY+ VK L ++GV V L+G + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-Q 181 Query: 182 YAMRIWLDPARMGAFKLSSSDVMQVLQANNYQSAVGQTNGVYTL------FNGTADTQVA 235 YAMRIWLD + +KL+ DV+ L+ N Q A GQ G L + A T+ Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 TIEELKRLVI-GSKDGLVVRLGDIADVSLEKSHDIYRALANGKEAVVIGLDVTPTANPLN 294 EE ++ + + DG VVRL D+A V L + A NGK A +G+ + AN L+ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 VAADTRALLPEIERNLPPSIGSSILYDSSLAIDESIKEVVKTIGEAAIIVIVVITLFLGS 354 A +A L E++ P + YD++ + SI EVVKT+ EA ++V +V+ LFL + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRAVVIPIVTIPLSLIGVAIIMQMFGFTLNLMTLLAMVLAIGLVVDDAIVVVENVDRHIK 414 +RA +IP + +P+ L+G I+ FG+++N +T+ MVLAIGL+VDDAIVVVENV+R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 LGESPFRAAII-GTREIAVPVISMTITLAAVYAPIALMGGITGSLFKEFALTLAGSVFIS 473 + P + A +I ++ + + L+AV+ P+A GG TG+++++F++T+ ++ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GIVALTLSPMMCAKILKP-----HTTPNRFEMGVENFLTGLTRRYSNMLDAVMLHRPVIV 528 +VAL L+P +CA +LKP H F Y+N + ++ + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 AFAIIVFASLPVLFKFIPSELAPNEDKGVVMMMGTAPSTANLDYIQANMGLVTDMIKAQP 588 ++ A + VLF +PS P ED+GV + M P+ A + Q + VTD Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 ESAASLAF----VGVPSSSQAFGIA--PLVPWSER----EKSQKQMQEFFAKEVKHIPGM 638 ++ F +Q G+A L PW ER ++ + E+ I Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK-MELGKIRDG 660 Query: 639 AITTFQMPE--LPGASSGLPIQFVITTSNSFASLFQIGTGVLEKVQKSPLFVYSEI-NLK 695 + F MP G ++G + + +L Q +L + P + S N Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 696 FDSGTMKLHIKRDLAGTYGVTMQDIGITLATMMSDGYVNRINLDGRSYEVIPQVERKLRA 755 D+ KL + ++ A GV++ DI T++T + YVN GR ++ Q + K R Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 756 NPESLANYYVKAADGKSIPLSSLVDIEMVAEPRSLPHFNQMNALTVGGVAAPGVAIGDAI 815 PE + YV++A+G+ +P S+ V L +N + ++ + G AAPG + GDA+ Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 816 NFLQNIGDNELPKGYSYDFLGEARQFVTEGSALYATFLLAIAIIFLVLASQFESLKDPLV 875 ++N+ ++LP G YD+ G + Q G+ A ++ ++FL LA+ +ES P+ Sbjct: 841 ALMENL-ASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 876 ILVSVPLAISGALIVLGWTHVFGLAKINIYTQVGLITLVGLITKHGILMCEVAKEEQLHR 935 +++ VPL I G L+ + K ++Y VGL+T +GL K+ IL+ E AK+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQ----KNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 936 GLSKLEAIKLAATIRLRPILMTTAAMIAGLLPLLFASGAGAVARFNIGIVIVAGLSIGTI 995 G +EA +A +RLRPILMT+ A I G+LPL ++GAG+ A+ +GI ++ G+ T+ Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 996 FTLFVLPVIYTYLAEKHE 1013 +F +PV + + + Sbjct: 1016 LAIFFVPVFFVVIRRCFK 1033
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 5e-07 Identities = 23/130 (17%), Positives = 33/130 (25%), Gaps = 35/130 (26%) Query: 71 TISNELAGRVTSINFENGSRVEKGQLLAELDAKVERANLKSKMVQLPAAEADFKRLSKLY 130 I V I + G V KG +L +L A A+ L A + R L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 131 -----------------------------------AQKSVSKQDLDNSESKYLALQADIE 155 Q S + E +A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 156 SLKATIERRE 165 ++ A I R E Sbjct: 218 TVLARINRYE 227 Score = 43.7 bits (103), Expect = 8e-07 Identities = 37/253 (14%), Positives = 75/253 (29%), Gaps = 71/253 (28%) Query: 88 GSRVEKGQLLAELDAKVERANLKSKMVQLPAAEADFKRLSKLYAQKSVSKQDLDNSESKY 147 + + AE + R N ++ S L +++++K + E+KY Sbjct: 204 QKELNLDKKRAERLTVLARINRYEN--LSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 148 LALQADIESLKATIER-------------------------------------------- 163 + ++ K+ +E+ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 164 ------REISAPFSGLVGIRNIN-LGEYLQPGT---DIVRLEDISTMKIRFTIPQTQLPR 213 I AP S V ++ G + IV +D T+++ + + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDD--TLEVTALVQNKDIGF 379 Query: 214 IAVGQKIHVFVDSYPEQ---PFEGEIAAIEP--------AVFYQSGLIQVQARIP--NDN 260 I VGQ + V+++P G++ I + + + + + N N Sbjct: 380 INVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKN 439 Query: 261 AKLRSGMFARVSI 273 L SGM I Sbjct: 440 IPLSSGMAVTAEI 452
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 7e-14 Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 6/136 (4%) Query: 2 DSKRDLILRSAEKIIATEGLHNLSMQKLAADAGVAAGTIYRYFKDKEDLIIELRKDVLQQ 61 R IL A ++ + +G+ + S+ ++A AGV G IY +FKDK DL E+ + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 62 IASKLLENINE--GSFDQKFRRLWFNIVALGRKQSHANLSFAQYSHL---PGVDAPEHQA 116 I LE + G R + +++ + L H G A QA Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 117 FEREIFQQLHQLFEQA 132 +R + + + EQ Sbjct: 130 -QRNLCLESYDRIEQT 144
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 174 bits (442), Expect = 2e-59 Identities = 88/136 (64%), Positives = 111/136 (81%), Gaps = 1/136 (0%) Query: 1 MSLIKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSIV 60 MS+IKEF+ FA RGNV+D+AVG+IIGAAFGKIVSS VADIIMPP+G+++GG++F ++ Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60 Query: 61 LQAAQGDAPAVVIAYGKFIQTIIDFTIIAFAIFMGLKAINSLKRKQEEAPKAPPAPTKDQ 120 L+ AQGD PAVV+ YG FIQ + DF I+AFAIFM +K IN L RK+EE P A PAPTK++ Sbjct: 61 LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEE 119 Query: 121 ELLSEIRDLLKAQQEK 136 LL+EIRDLLK Q + Sbjct: 120 VLLTEIRDLLKEQNNR 135
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 93.0 bits (231), Expect = 6e-23 Identities = 39/290 (13%), Positives = 91/290 (31%), Gaps = 28/290 (9%) Query: 71 LAQLEDNQFSAKVSQAEALLASAKADMQTLAAKVELQHALISQASAGVVAAQADKLRAEQ 130 + + + S + ++ + ++ + A A + + + Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 131 QLSRAKKLKVSNYSSQDDVDQLQAGFDSAAAGLDEAKA--------LLVAKERELAVFN- 181 +L L ++ V + + + A L K+ +L AKE V Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 182 ------AQLNQAGSVVEQSNAALELAKIQLNDTRVTAPFSGVIGKRGAM-VGQYVQPGQA 234 +L Q + L + + + + AP S + + G V + Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 235 LYSLVPDGAV-WITANFKETQIQHMQPGQSVQVSLDAFPDKTFTGVIDSLSPASGAKFSL 293 L +VP+ +TA + I + GQ+ + ++AFP G + K Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTR-YGYLV-------GKVKN 407 Query: 294 LPAENATGNFTKIVQRIPVRIRLDLSAE---EARVVPGLSAVVKVDTASH 340 + + +V + + I + + + G++ ++ T Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457 Score = 56.0 bits (135), Expect = 8e-11 Identities = 23/128 (17%), Positives = 47/128 (36%), Gaps = 2/128 (1%) Query: 59 VTDNQHVRKGELLAQLEDNQFSAKVSQAEALLASAKADMQTLAAKVELQHALISQASAGV 118 V + + VRKG++L +L A + ++ L A+ + L + Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR-SIELNKLPELKL 170 Query: 119 VAAQADKLRAEQQLSRAKKLKVSNYSS-QDDVDQLQAGFDSAAAGLDEAKALLVAKEREL 177 + +E+++ R L +S+ Q+ Q + D A A + E Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 178 AVFNAQLN 185 V ++L+ Sbjct: 231 RVEKSRLD 238
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (309), Expect = 2e-32 Identities = 89/421 (21%), Positives = 177/421 (42%), Gaps = 19/421 (4%) Query: 18 SEYERGSRRSWIAVFGGLIGAFMAILDIQITNASMKEIQGSLGATLEEGSWISTAYLVAE 77 + Y + + R + I +F ++L+ + N S+ +I +W++TA+++ Sbjct: 3 TSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 78 MIAIPLSGWLSTGLSVRRYLLWTTAAFIFASILCSISWN-LEAMIAFRALQGFFGGALIP 136 I + G LS L ++R LL+ F S++ + + +I R +QG A Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 137 LAFRLILEFLPENKRAVGMALFGVTATFAPSIGPTLGGWLTEHFSWHYLFYINVPPGLLV 196 L ++ ++P+ R L G +GP +GG + + W YL +P ++ Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITII 180 Query: 197 MAMLAYGLEKRPVVWDKLKNADLAGIVTMALGMGCLEVVLEEGNRKDWFGSDLIRNLAII 256 L K+ V + D+ GI+ M++G+ + F + + I+ Sbjct: 181 TVPFLMKLLKKEVRIKG--HFDIKGIILMSVGIVFFML----------FTTSYSISFLIV 228 Query: 257 AAVNLVLFVWIQLKRKDPLVNLRLLGKRDFVLSTIAYFLLGMALFGAIYLIPLYLSQVHD 316 + ++ ++FV K DP V+ L F++ + ++ + G + ++P + VH Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 317 YTPLEIGEVIMWMGFPQLLVL-PLVPRLMQRFDGRYLAAFGFFMFALSYYMNSQMTADYA 375 + EIG VI++ G +++ + L+ R Y+ G ++S+ S + Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL--LET 346 Query: 376 GPQMIASQVVRALG-QPFILVPIGMLATAHLKPHENPSASTVLNVMRNLGGAFGIALVAT 434 + +V LG F I + ++ LK E + ++LN L GIA+V Sbjct: 347 TSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 435 L 435 L Sbjct: 407 L 407
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.8 bits (90), Expect = 2e-06 Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 5/72 (6%) Query: 81 ASIGRVVVSPAGRGKGLAMPLMQRAIESVLSTWPAAGIQIGAQDYLKS---FYQKLGFSA 137 A I + V+ R KG+ L+ +AIE G+ + QD S FY K F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFII 148 Query: 138 CS-EMYLEDGIP 148 + + L P Sbjct: 149 GAVDTMLYSNFP 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 357 bits (918), Expect = e-121 Identities = 134/459 (29%), Positives = 219/459 (47%), Gaps = 41/459 (8%) Query: 34 LKQAAWNCVKAVSAAEALVLLQKYELRVAIAFISDTNQTALAKEIAIIQAEYPSLHWIAV 93 L +A ++ +AA + + + + + ++ A + I+ P L + + Sbjct: 23 LSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL-LPRIKKARPDLPVLVM 81 Query: 94 TD-SALEQHCSWLSAANFVDYYHRPFDWNRFADTLGHAWGMAQLTPSKGGKGPAKVLTTI 152 + + + DY +PFD +G A + PSK + + Sbjct: 82 SAQNTFMTAIKASEKGAY-DYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLV 140 Query: 153 KGEHPLLQQLRQRLHKFSQSDETVLLSGETGSGKGLCAKTLHSLSKRHEGPFITVNCGAL 212 G +Q++ + L + Q+D T++++GE+G+GK L A+ LH KR GPF+ +N A+ Sbjct: 141 -GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI 199 Query: 213 PTGLIHSTLFGHEKGAFTDADKRYIGHLEQAHGGTLFLDEIADLPLDLQVNLLHFLDDKH 272 P LI S LFGHEKGAFT A R G EQA GGTLFLDEI D+P+D Q LL L Sbjct: 200 PRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGE 259 Query: 273 IMRIGGNAPIKVDCRLLFASHQDLEAAIDEGRFREDLYHRINVLRLHVPSLRQYSDEVML 332 +GG PI+ D R++ A+++DL+ +I++G FREDLY+R+NV+ L +P LR ++++ Sbjct: 260 YTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPD 319 Query: 333 LAEQFLLE-HSDNCTQFHFSDEARCAMKHYNWPGNVRELRNRIRRAMVLTDDCIITAQLL 391 L F+ + + F EA MK + WPGNVREL N +RR L +IT +++ Sbjct: 320 LVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREII 379 Query: 392 GLD---SLTANRTSQ---------------------------------DLARCRAEHEAE 415 + + + + R AE E Sbjct: 380 ENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYP 439 Query: 416 VLLKAISDHKHNISAAARSLNISRATFYRLLKKCQIKVP 454 ++L A++ + N AA L ++R T + +++ + V Sbjct: 440 LILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVY 478
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 0.001 Identities = 21/107 (19%), Positives = 37/107 (34%), Gaps = 22/107 (20%) Query: 610 LVIRNLFSNAIKH---HDQAEGVIKVVCSASNTHYWFSVIDDGPGISTKYHGKVFEMFQT 666 ++++ L N IKH G I + + N V + G Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS---------------- 301 Query: 667 LRPRDEVEGSGLGLSLVKKTVESLGGK---IQLESEGRGCCFRFSWP 710 L ++ E +G GL V++ ++ L G I+L + P Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 6e-09 Identities = 23/109 (21%), Positives = 43/109 (39%), Gaps = 10/109 (9%) Query: 11 TILLVDDDDVDYMAVQRAMKQLRLLNPLVRARDGLEALSILTHSEAIKGSYLILLDLNMP 70 TIL+ DDD + +A+ + + + + + L++ D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGD----GDLVVTDVVMP 58 Query: 71 RMNGFEFLEHIRS-DPTLSSSVVFMLTTSSTDEDRMKAYSHHVAGYMVK 118 N F+ L I+ P L V +++ +T +KA Y+ K Sbjct: 59 DENAFDLLPRIKKARPDL---PVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 1e-12 Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 6/137 (4%) Query: 3 LLLIDDDEVDRTAIIRALRQSKLAFNVVEANCAFDGLNLALERHFDGILLDYLLPDANGL 62 +L+ DDD RT + +AL S+ ++V + A D ++ D ++PD N Sbjct: 6 ILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EVLIKLNSMTQDQTVVVMLSRYEDEKLAQRCIELGAQDFLLK---DEVNSRILSRAIRYA 119 ++L ++ D V+VM S A + E GA D+L K I+ RA+ Sbjct: 64 DLLPRIKKARPDLPVLVM-SAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 120 KQRSSMALALRNSHQKL 136 K+R S L Sbjct: 123 KRRPSKLEDDSQDGMPL 139
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 31.1 bits (70), Expect = 0.004 Identities = 35/200 (17%), Positives = 65/200 (32%), Gaps = 54/200 (27%) Query: 47 VAIQGGIDYSHDSGFYAGTWASNVDFGDDTSYELDLYAGYGGNITEDLSYDIGYLYYAYP 106 + G HD+GF +N + + GY + + +++GY + Sbjct: 30 TGAKLGWSQYHDTGFI-----NNNGPTHENQLGAGAFGGY--QVNPYVGFEMGYDWLGRM 82 Query: 107 DAEGSID-------------------------FGELHGAITWKWFELSYSQVINAGDDVA 141 +GS++ + L G + W + S V D Sbjct: 83 PYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMV---WRADTKSNVYGKNHDTG 139 Query: 142 AEPLDNKDMSYLAATASFPLTDKLSLSLHYGYSSGDVVESWFGEDNYADYNVTLSADTSM 201 P+ A + +T +++ L Y +++ N D + T+ Sbjct: 140 VSPV-------FAGGVEYAITPEIATRLEYQWTN-----------NIGDAH-TIGTRPDN 180 Query: 202 GTVSFMVSDTDLQGDDAKVV 221 G +S VS QG+ A VV Sbjct: 181 GMLSLGVSYRFGQGEAAPVV 200
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 109 bits (274), Expect = 3e-35 Identities = 44/88 (50%), Positives = 66/88 (75%) Query: 2 NKTELIAKIAENADITKAEAARALKSFEAAITESMKNGDKISIVGFGSFETTTRAARTGR 61 NK +LIAK+AE ++TK ++A A+ + +A++ + G+K+ ++GFG+FE RAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIQIAEATVPKFKAGKTLRDSV 89 NPQTG+EI+I + VP FKAGK L+D+V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 1/131 (0%) Query: 1 MQNPHILIVEDEAVTRNTLRSIFEAEGYVVTEANDGAEMHKAMQENKINLVVMDINLPGK 60 M IL+ +D+A R L GY V ++ A + + + +LVV D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELREIN-NIGLIFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLT 119 N L +++ ++ ++ ++ ++ + I E GA DY+ KPF+ EL L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RVNSAGNEVEE 130 +++E+ Sbjct: 121 EPKRRPSKLED 131
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.9 bits (70), Expect = 0.009 Identities = 18/81 (22%), Positives = 27/81 (33%), Gaps = 5/81 (6%) Query: 202 DYSAALLAEALKASAVEIWTDVAGIYTTDPRLAPNAHPIAEISFNEAAEMATFGAKVLHP 261 D + LAE + A I TDV G + E+ E + G Sbjct: 216 DLAGEKLAEEVNADIFMILTDVNGAALY--YGTEKEQWLREVKVEELRKYYEEGH--FKA 271 Query: 262 ATILPAVRQQIQVFVGSSKEP 282 ++ P V I+ F+ E Sbjct: 272 GSMGPKVLAAIR-FIEWGGER 291
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 3e-14 Identities = 27/159 (16%), Positives = 62/159 (38%), Gaps = 9/159 (5%) Query: 6 SVLVVDDHPLLRKGICQLIASDPDFSLFGEVGGGLDALSAVATDEPDIVLLDLNMKGMTG 65 ++LV DD +R + Q S + + +A + D+V+ D+ M Sbjct: 5 TILVADDDAAIRTVLNQ-ALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 66 LDTLNAMRQEGVTSRIVILTVSDAKQDVIRLLRAGADGYLLKDTEPDLLLDKLKNAMLGH 125 D L +++ +++++ + I+ GA YL K + L+ + A+ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL--- 119 Query: 126 RVISDEVEEYLYELKNAADEQEWISSLTPRELQILQQLA 164 E + +L++ + + + + +I + LA Sbjct: 120 ----AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>PF06580#Sensor histidine kinase Length = 349 Score = 40.6 bits (95), Expect = 1e-05 Identities = 26/140 (18%), Positives = 55/140 (39%), Gaps = 17/140 (12%) Query: 410 INEGVSTAYVQLRELLSTFRLTIKEPNLKN-AMEAMLEQLRANTDI-------KIHLDYK 461 I E + A L L R +++ N + ++ L + + + ++ + + Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 462 LSPQWLEAKQHIHILQITREATLNAIKHA-----NASQINIRCYKDDNGMVNISVSDNGI 516 ++P ++ + ++Q E N IKH +I ++ KD NG V + V + G Sbjct: 246 INPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKD-NGTVTLEVENTGS 301 Query: 517 GIGYLKERDQHFGIGIMHER 536 + G+ + ER Sbjct: 302 LALKNTKESTGTGLQNVRER 321
>PHPHLIPASEA1#Bacterial phospholipase A1 protein signature. Length = 289 Score = 217 bits (553), Expect = 1e-71 Identities = 107/300 (35%), Positives = 156/300 (52%), Gaps = 26/300 (8%) Query: 6 KGIALIGLLTCTGLQAEESLVKGRVQDE-----------LATSERPFVITPHKVNYILPA 54 +G L + + A+E+ VK V D L + PF + P+ NY++ Sbjct: 5 QGWLLPVFMLPMAVYAQEATVK-EVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYT 63 Query: 55 TYNPDPNMAPFAQDAAENDYTLDEMEAKFQISFKFPLWYNVFGDNGHLFFAYTNQSYWQL 114 + A + D AEN + E KFQ+S FPLW + G N L +YT +S+WQL Sbjct: 64 QTSDLNKEAIASYDWAENA---RKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQL 120 Query: 115 YNKDISSPFRETNHEPEIFMLFNNDWKIGSVTNSFWGFGAVHQSNGKSGLLSRSWNRIYG 174 N + SSPFRETN+EP++F+ F D++ T G H SNG+S SRSWNR+Y Sbjct: 121 SNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYT 180 Query: 175 TMIFDAGPLAFATKVWWRIPEDEKTDIHQPRGDDNPDIDEYIGKAEFVGVYGIDDHRFTL 234 ++ + G K W+ + DDNPDI +Y+G + Y + D + Sbjct: 181 RLMAENGNWLVEVKPWYVVGNT----------DDNPDITKYMGYYQLKIGYHLGDAVLSA 230 Query: 235 TLKTNFKDIDRGSAEFTWSYPIIGNLRLYTQYFNGYGESLIDYNYHNQRIGIGLSLNDIL 294 + N+ G AE SYPI ++RLYTQ ++GYGESLIDYN++ R+G+G+ LND+ Sbjct: 231 KGQYNWNT-GYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF 289
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 68.0 bits (166), Expect = 3e-14 Identities = 47/154 (30%), Positives = 70/154 (45%), Gaps = 17/154 (11%) Query: 41 VDDGKSTLIGRLLHDSAQIYEDQLASLKNDSAKMGTTGEAIDLALLVDGLQAEREQGITI 100 VD GK+TL LL++S I +L S+ + + D ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAI--TELGSVDKGTTRT-------------DNTLLERQRGITI 56 Query: 101 DVAYRYFSSDKRKFIIADTPGHEQYTRNMATGASTCDLAVILVDARYGVQTQTKRHAFIA 160 F + K I DTPGH + + S D A++L+ A+ GVQ QT+ Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 161 SLLGIRHFVVAVNKMDLLGFD-EQVFNRIRNDFS 193 +GI + +NK+D G D V+ I+ S Sbjct: 117 RKMGIPT-IFFINKIDQNGIDLSTVYQDIKEKLS 149
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 30/146 (20%), Positives = 53/146 (36%), Gaps = 23/146 (15%) Query: 478 SLVQDMLHTSWLRMKKQFHELNIDISPEIELNSYPGALGQVLENLVSNALTHAFEDV-GN 536 ++V L + ++ + + I+P I P L Q L V N + H + Sbjct: 223 TVVDSYLQLASIQFEDRLQ-FENQINPAIMDVQVPPMLVQTL---VENGIKHGIAQLPQG 278 Query: 537 GQINITAYSLEDAFVAITVTDNGGGMDDATLKQIFDPFFTTRRGKGGTGLGLHLAHQLVT 596 G+I + ++ V + V + G + K TG GL + + Sbjct: 279 GKILLKGT-KDNGTVTLEVENTGSLA--------------LKNTKESTGTGLQNVRERLQ 323 Query: 597 QLLGG--YIKVTSELGKGTCFTLTIP 620 L G IK++ + GK + IP Sbjct: 324 MLYGTEAQIKLSEKQGKVNA-MVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 42.5 bits (100), Expect = 5e-06 Identities = 23/146 (15%), Positives = 47/146 (32%), Gaps = 18/146 (12%) Query: 25 AVKILTVDDDINFQRSTAFALSTLTILGSKIELTQAFSYAEACQIVANEDDFAIALVDVV 84 IL DDD + ALS ++ + A + +A D + + DVV Sbjct: 3 GATILVADDDAAIRTVLNQALSRA-----GYDVRITSNAATLWRWIA-AGDGDLVVTDVV 56 Query: 85 METEDAGLRLVRGIREVLGNEKIRIILLTGQPGMAPVFNVMR----DY-----DINDYWT 135 M E+ L+ I++ + +++++ Q DY D+ + Sbjct: 57 MPDEN-AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG 113 Query: 136 KSELSADRLQTILTTNLRSYQQISNI 161 + + + Q + Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMPL 139
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 8e-04 Identities = 31/143 (21%), Positives = 47/143 (32%), Gaps = 12/143 (8%) Query: 249 VVNLLFAPAIGRFIGRIGERNALTVEYIGLFFVFVSYALVEQPHMAAALY---VIDHLLF 305 ++ AP +G R G R L + L V YA++ LY ++ + Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLL---VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITG 110 Query: 306 AMAIAMKTYFQKIADSKDIAAT---MSVSFTINHIAAVVIPVLLGLLWLSDPALVFYIGA 362 A Y I D + A MS F +A PVL GL+ P F+ A Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG---PVLGGLMGGFSPHAPFFAAA 167 Query: 363 GFAVCSLVLALNVPRHPSPGNET 385 + + + G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERR 190
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 78.0 bits (192), Expect = 1e-17 Identities = 31/172 (18%), Positives = 82/172 (47%), Gaps = 4/172 (2%) Query: 442 VTIVEERTIGPTLGAENIQNGFAALGLGMGITLLFMALWYR-RLGWVANVALIANMVILF 500 + I ++GP + E + +L + + ++ + + + A VAL+ ++++ Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 501 GLLALIPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFALA--IDTGFDSA 558 GL A++ L +A L+ G +++ V++F+R+++ L + ++ L ++ + Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 559 FSTIFDANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALI 610 S TT++ V + G I+GF + G+ T ++ ++ ++ ++ Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV 305
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 238 bits (609), Expect = 1e-79 Identities = 91/305 (29%), Positives = 154/305 (50%), Gaps = 20/305 (6%) Query: 2 KNINLTKWRYVSSAISIFLMLASLTIIGMKGFNWGLDFTGGVVTEVQLDRRITSSELQPL 61 N + +W++ + +I +M+AS+ + + G N+G+DF GG + I + Sbjct: 12 TNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAA 71 Query: 62 LNAAYQQEVTVISASEP--------------------GRWVLRYADTAQSNVDIAQTLAP 101 L +V + +P G N A Sbjct: 72 LEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAV 131 Query: 102 LGEVQVLNTSIVGPQVGKELAEQGGLALLVAMLCILGYLSYRFEWRLASGALFALVHDVI 161 +++ + VGP+V EL +LL A + I+ Y+ RFEW+ A GA+ ALVHDV+ Sbjct: 132 DPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 162 FVLAFFSLTQMEFNLTVLAAVLAILGYSLNDSIIIADRIRELLIAKPKLAIQEINNQAIV 221 + F++ Q++F+LT +AA+L I GYS+ND++++ DR+RE LI + ++++ N ++ Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVN 251 Query: 222 ATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISVGTSLPEFLGLT 281 T SRT++T TTL+ + + I GG + GF AM G+ TGT+SS+ V ++ F+GL Sbjct: 252 ETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLD 311 Query: 282 PEHYK 286 K Sbjct: 312 RNKEK 316
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.002 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 198 VLMVGPPGTGKTLLAKAIAGESK---VPFFT-----ISGSDFVEMFVGV------GASRV 243 +++ G GTGK L+A+A+ K PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 244 RD-MFEQAKKSAPCIIFIDEID 264 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>adhesinb#Adhesin B signature. Length = 310 Score = 31.4 bits (71), Expect = 0.003 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 142 REARRTFEVIAEELDIVIQKNGTMAFDNAIIAY----EPLWAVGTGKSATPEQAQEVHAF 197 +EA+ F I E +++ G F AY +W + T + TP+Q + + Sbjct: 186 KEAKEKFNNIPGEKKMIVTSEG--CFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEK 243 Query: 198 IRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQ 232 +RK + L+ S ++ Sbjct: 244 LRKT----------KVPSLFVESSVDDRPMKTVSK 268
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 121 bits (305), Expect = 2e-39 Identities = 64/110 (58%), Positives = 83/110 (75%) Query: 1 MYEVLVVVYLLVALGLIGLILIQQGKGADMGASFGAGASGTLFGSSGSGNFLTRTTAILA 60 MYE L+VV+L+VA+GL+GLI++QQGKGADMGASFGAGAS TLFGSSGSGNF+TR TA+LA Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 IAFFTLSLLIGNLSANHAKNEDAWKNLGADEQVTQPVDQATEKSETKIPD 110 FF +SL++GN+++N W+NL A + Q A K + IP+ Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN 110
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 69.1 bits (169), Expect = 4e-14 Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 18/133 (13%) Query: 396 IMGHVDHGKTSLLDYIRRAKVAAGEAG------------------GITQHIGAYHVETEN 437 ++ HVD GKT+L + + A E G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 438 GMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAV 497 + +DTPGH F A R D +L+++A DGV QT + +P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 498 NKMDKPEADIDRV 510 NK+D+ D+ V Sbjct: 128 NKIDQNGIDLSTV 140
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.3 bits (143), Expect = 4e-13 Identities = 36/160 (22%), Positives = 60/160 (37%), Gaps = 5/160 (3%) Query: 23 LAKALEVFWQKGFEGTSLTDLTQAMGINKPSLYAAFGNKEQLFLKAIELYEQRPCAFFYP 82 L AL +F Q+G TSL ++ +A G+ + ++Y F +K LF + EL E Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 83 SLEK--ETAYQVVEAMLYGAASSLVDESHPQGCLIVQGALACSEAGQAIKDTLITRRRDG 140 K V+ +L S V E + + + C G+ R Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK-CEFVGEMAVVQQAQRNLCL 135 Query: 141 E--QALCQRLQRAKDEGDLPADADPLLLSRYIGTVLQGMA 178 E + Q L+ + LPAD + + + G+ Sbjct: 136 ESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.6 bits (108), Expect = 2e-07 Identities = 23/123 (18%), Positives = 48/123 (39%), Gaps = 5/123 (4%) Query: 64 SVTLVPRVSGYIASVNFKEGALVKKGDVLFHIDASVFEAEVARLRADLASALSAE---QL 120 S + P + + + KEG V+KGDVL + A EA+ + ++ L A + Q+ Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 121 ATNDLERARKLFAQKAVSAELLDTRESNKRQTTAAVASVKAALLR--AELDLDYTQVRAP 178 + +E + + + E + T+ + + + +L+ + RA Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAE 215 Query: 179 IDG 181 Sbjct: 216 RLT 218 Score = 39.8 bits (93), Expect = 2e-05 Identities = 20/102 (19%), Positives = 41/102 (40%), Gaps = 10/102 (9%) Query: 101 EAEVARLRADLASALSAEQLATNDLERARKLFAQKAVSAELLDTRESNKRQTTAAVASVK 160 E+ ++ L S A + + +LF + + +L RQTT + + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLF-KNEILDKL--------RQTTDNIGLLT 315 Query: 161 AALLRAELDLDYTQVRAPIDGRASYANV-TAGNYVSAGQSVL 201 L + E + +RAP+ + V T G V+ ++++ Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1035 bits (2678), Expect = 0.0 Identities = 419/1043 (40%), Positives = 640/1043 (61%), Gaps = 18/1043 (1%) Query: 2 LSQFFIKRPIFAAVLSLLFFITGAIAVWQLPITEYPEVVPPTVVVTANYPGANPKVIAET 61 ++ FFI+RPIFA VL+++ + GA+A+ QLP+ +YP + PP V V+ANYPGA+ + + +T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 62 VASPLEQEINGVEDMLYMSSQATSDGRMTLTITFAIGTDVDRAQTQVQSRVDRAMPRLPQ 121 V +EQ +NG+++++YMSS + S G +T+T+TF GTD D AQ QVQ+++ A P LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EVQRLGIVTEKSSPDLTMVVHLLSPDNRYDMLYLSNYAALNVKDELARIKGVGAVRLFGA 181 EVQ+ GI EKSS MV +S + +S+Y A NVKD L+R+ GVG V+LFG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 182 GEYSLRIWLDPNKVSALGMSPAEIIAAVREQNQQAAAGSLGAQPSGNA-DFQLLINVKGR 240 +Y++RIWLD + ++ ++P ++I ++ QN Q AAG LG P+ I + R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LTELSEFEDIIIKVGQNGEVIRLKDVARVELGATSYALRSLLDNKDAVAIPVFQASGSNA 300 EF + ++V +G V+RLKDVARVELG +Y + + ++ K A + + A+G+NA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 IQISDDVRAEMARLAKSFPEGLQYEIVYDPTVFVRGSIHAVVKTLLEAVLLVVLVVVLFL 360 + + ++A++A L FP+G++ YD T FV+ SIH VVKTL EA++LV LV+ LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QTWRASIIPLVAVPVSLVGTFAFMHLMGFSLNALSLFGLVLAIGIVVDDAIVVVENVERN 420 Q RA++IP +AVPV L+GTFA + G+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 IAS-GLSPIAATQKAMKEVTGPIVATTLVLAAVFIPTAFMSGLTGQFYKQFALTITISTF 479 + L P AT+K+M ++ G +V +VL+AVFIP AF G TG Y+QF++TI + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 480 ISAINSLTLSPALSALLLKGHDAPKDALTRLMDKLFGGWLFTPFNRLFNRASEGYGYLVR 539 +S + +L L+PAL A LLK A G F FN F+ + Y V Sbjct: 480 LSVLVALILTPALCATLLKPVSAE--------HHENKGGFFGWFNTTFDHSVNHYTNSVG 531 Query: 540 KVIRFGGIIGLVYLGMVALTGVQFVNTPTGYVPGQDKQYLVAFAQLPDAASLERTDAVIK 599 K++ G L+Y +VA V F+ P+ ++P +D+ + QLP A+ ERT V+ Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 600 KMSDIALNH--PGVAHSIAFPGLSINGFTNSPNSGVVFVALDDFELRKSPELSANAIAGQ 657 +++D L + V G S +G + N+G+ FV+L +E R E SA A+ + Sbjct: 592 QVTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHR 649 Query: 658 LNQQFAGIQDAFIAIFPPPPVQGLGTIGGFRLQIQDRANLGYEALYQVTQQVMYKAWADP 717 + I+D F+ F P + LGT GF ++ D+A LG++AL Q Q++ A P Sbjct: 650 AKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 718 -QLAGIFSSYQVNVPQLELDIDRTKAKQQAVSLDQIFQTLQTYMGSTYVNDFNRFGRTYQ 776 L + + + Q +L++D+ KA+ VSL I QT+ T +G TYVNDF GR + Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK 769 Query: 777 VNMQADEAFRQSPQQISQLKVPNVNGDMIPLGSFINVSQSAGPDRVMHYNGFTTAEINGG 836 + +QAD FR P+ + +L V + NG+M+P +F G R+ YNG + EI G Sbjct: 770 LYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE 829 Query: 837 PAPGVSSGQAQAAIEKILAETLPIGMTYEWTELTYQQILAGNTGLLVFPLVILLVFMVLA 896 APG SSG A A +E + ++ LP G+ Y+WT ++YQ+ L+GN + + ++VF+ LA Sbjct: 830 AAPGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLA 888 Query: 897 AQYESLSLPLAIILIIPMTLLSALSGVLIYGGDNNIFTQIGLIVLVGLATKNAILIVEFA 956 A YES S+P++++L++P+ ++ L ++ N+++ +GL+ +GL+ KNAILIVEFA Sbjct: 889 ALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFA 948 Query: 957 KEKQDH-GMEVMESILEAARLRLRPILMTSIAFIMGVVPMVFSTGAGAEMRQAMGVAVFA 1015 K+ + G V+E+ L A R+RLRPILMTS+AFI+GV+P+ S GAG+ + A+G+ V Sbjct: 949 KDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMG 1008 Query: 1016 GMIGVTLFGLILTPLFYYALAKR 1038 GM+ TL + P+F+ + + Sbjct: 1009 GMVSATLLAIFFVPVFFVVIRRC 1031
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 64.1 bits (156), Expect = 2e-13 Identities = 51/237 (21%), Positives = 105/237 (44%), Gaps = 15/237 (6%) Query: 7 LWLCVLLMMFPQIMETIYSPALPNIAENFAVSVTSASQTLSVYFIAFAVGVFCWGRLADI 66 +WLC+L + E + + +LP+IA +F S + + + + F++G +G+L+D Sbjct: 17 IWLCILSFFSV-LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 67 IGRRNAMLAGLLCYAIGSACALM-ISDFTLLLFARVLSAFGAA----VGSVITQTMMRDS 121 +G + +L G++ GS + S F+LL+ AR + GAA + V+ + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 122 YNGEELAKVFSVMGMSLGISPIIGLLLGSILSAYWGYQGVFVALMVSAIVLLFLSVKSLP 181 G+ + S++ M G+ P IG ++ + +W Y + + + I+ + +K L Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSY---LLLIPMITIITVPFLMKLLK 190 Query: 182 ETKPEHTQKIAIVELAIKMLTDIGIIKNTLLVASFNLMWFSYFSLAPFMFEARGLST 238 + I + L +GI+ L S+++ + L+ +F Sbjct: 191 KEV-RIKGHFDIKGII---LMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKV 243
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 779 bits (2012), Expect = 0.0 Identities = 308/1032 (29%), Positives = 517/1032 (50%), Gaps = 28/1032 (2%) Query: 3 LSDVSVKRPVVAIVLSLLLCVFGLVSFTKLSVREMPDVESPVVTVSTSYSGASAAIMESQ 62 +++ ++RP+ A VL+++L + G ++ +L V + P + P V+VS +Y GA A ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITKTLEDELTGISGIDEITSTT-RNGSSRITVKFLLGWNLTEGVSDVRDAVARAQRRLPE 121 +T+ +E + GI + ++ST+ GS IT+ F G + V++ + A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DANDPVVSKDNGSGEPSVYVNLSSSVMDRTQ--LTDYAQRVLEDRFSLISGVSSISISGG 179 + +S + S + S TQ ++DY ++D S ++GV + + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 LYKVMYVKLRPEQMAGRNVTVTDIINALRKENVETPGGQVRNDTTV------MSVRTKRL 233 Y + + L + + +T D+IN L+ +N + GQ+ + S+ + Sbjct: 181 QYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YYTPKDFDYLVVRTASDGTPIYLKDVADVAVGAQNENSTFKSDGIVNLSLGVITQSDANP 293 + P++F + +R SDG+ + LKDVA V +G +N N + +G LG+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LIVAQEVHKEVDRIQDFLPEGTSLVVDFDSTVFIDRSINEVYNTLYVTGALVVLVLYIFI 353 L A+ + ++ +Q F P+G ++ +D+T F+ SI+EV TL+ LV LV+Y+F+ Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GQARATLIPAVTVPVSLISAFIAANMFGYSINLLTLMALILAIGLVVDDAIVVVENIFHH 413 RATLIP + VPV L+ F FGYSIN LT+ ++LAIGL+VDDAIVVVEN+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-ERGEEPLLAAYKGTREVGFAVVATTAVLVMVFLPISFMEGMVGLLFTEFSVMLAVSVL 472 + E P A K ++ A+V VL VF+P++F G G ++ +FS+ + ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 FSSLIALTLTPVLSSKLLKANVK-----PNRFNRFVDSGFARMEKVYRVGVTQAIRFKWL 527 S L+AL LTP L + LLK F + ++ F Y V + + Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 528 APLVILACVGGSAWLMQQVPSQLAPQEDRGVLFAFVKGAEGTSYNRMTANMDIVEDRLMP 587 L+ V G L ++PS P+ED+GV ++ G + R +D V D + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 588 LLGQGVLRSFSVQAPAFGGRAGDQTGFVIMQLEDWEHRHVTAQQALGIIS---NALKDIP 644 V F+V +F G+ G + L+ WE R+ A +I L I Sbjct: 600 NEKANVESVFTVNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 DVMVRPM-MPGFRGQ-SSEPVQFVL---GGSDYAELFKWAQVLKEEANASP-MMEGADLD 698 D V P MP ++ F L G + L + L A P + + Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 699 YAETTPELIVTVDKERAAELGISVDEVSQTLEVMLGGRKETTYVDRGEEYDVYLRGDENS 758 E T + + VD+E+A LG+S+ +++QT+ LGG ++DRG +Y++ D Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 759 FNNVGDLSQIYMRSAKGELVTLDTLTHIEEVASAQKLSHTNKQKSITLKANISKGYTLGE 818 D+ ++Y+RSA GE+V T V + +L N S+ ++ + G + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 819 ALKFLDNKAIELLPKDISIGYTGESKDFKENQSSILIVFGLALLVAYLVLAAQFESFINP 878 A+ ++N A + LP I +TG S + + + + ++ +V +L LAA +ES+ P Sbjct: 839 AMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 879 LVVMFTVPMGVFGGFLGLLVTSQGINIYSQIGMIMLIGMVTKNGILIVEFANQLRDR-GL 937 + VM VP+G+ G L + +Q ++Y +G++ IG+ KN ILIVEFA L ++ G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 938 ALDKAIIDASTRRLRPILMTAFTTLVGAVPLIFSSGAGSESRIAVGTVVFFGMAFATFVT 997 + +A + A RLRPILMT+ ++G +PL S+GAGS ++ AVG V GM AT + Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 998 LFVIPAMYRLIS 1009 +F +P + +I Sbjct: 1018 IFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 5e-09 Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 3/108 (2%) Query: 50 PLAQSISLIGKLA-ADRAVVIAPQVTGKIKQIAVTSNQAVKKGQLLIELDDMKAQAAVAE 108 + + GKL + R+ I P +K+I V ++V+KG +L++L + A+A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 109 ANAFLNDETRKLREFEKLISRNAITQTEIDAQKASVDIARARLASAQA 156 + L +L + I +I ++ K + ++ + Sbjct: 139 TQSSL--LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 29.0 bits (65), Expect = 0.006 Identities = 10/39 (25%), Positives = 17/39 (43%) Query: 71 LSDLAAMGAEPAWMTLALTLPEVNEAWLSGFSEGLFEAA 109 + DL G + ++ L L+ A + G GLF+ Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTV 39
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.4 bits (66), Expect = 0.020 Identities = 24/131 (18%), Positives = 50/131 (38%), Gaps = 13/131 (9%) Query: 127 RLPNIPVMFVDLEDWHE-NGHVLTALELDNENTSHLDFNETLIEESKRIATLLSNDLHLI 185 + N + FV L+ W E NG +A + + L I + I + + L Sbjct: 619 QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK----IRDGFVIPFNMPAIVELG 674 Query: 186 NSYLPDPFYMSFNQQPQEQLCERDKYKARLTTVARQH--NLNTRNLHIEEGLPEDTI--- 240 + D + + L + + +L +A QH +L + + E + + Sbjct: 675 TATGFDFELIDQAGLGHDALTQ---ARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVD 731 Query: 241 AKEARRLNVNM 251 ++A+ L V++ Sbjct: 732 QEKAQALGVSL 742
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.4 bits (86), Expect = 1e-04 Identities = 44/247 (17%), Positives = 79/247 (31%), Gaps = 19/247 (7%) Query: 138 KSEHQLTLLDSYANHRLLIDTVAASYQRCKQIEAELKQLEASQQERIARKQLVQYQVEEL 197 SE + + A L + + A++K LEA + ARK ++ +E Sbjct: 108 LSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA 167 Query: 198 DEFDLKVGEFEEIEQEHKRLANGTELVDSCQASLFLLTDGEESNIESLLNKAVGLAENLQ 257 + K L +++ QA L + + + L+ Sbjct: 168 MN------FSTADSAKIKTLEAEKAALEARQAEL----EKALEGAMNFSTADSAKIKTLE 217 Query: 258 SYDPALTNVSTMLNEALIQVQESAGELQHYLSKLELDPAHFAYLEERLSKAMQLARKHHV 317 + AL L +AL + + LE A A LE R ++ + Sbjct: 218 AEKAALAARKADLEKALEGAMNFSTADSAKIKTLE---AEKAALEARQAELEKALEGAMN 274 Query: 318 SPDKLAEHHLALKSELTTLDDDENKLEDIQRQVEASKVAYLANAQKLSQSRARYAK---E 374 + L++E L+ ++ LE Q + + + L SR + E Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLE---HQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 375 LDKLVTQ 381 KL Q Sbjct: 332 HQKLEEQ 338 Score = 32.0 bits (72), Expect = 0.007 Identities = 33/203 (16%), Positives = 72/203 (35%), Gaps = 3/203 (1%) Query: 161 ASYQRCKQIEAELKQLEASQQE-RIARKQLVQYQVEELDEFDLKVGEFEEIEQEHKRLAN 219 A + K +EAE L A + + A + + + + + E +E L Sbjct: 208 ADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEK 267 Query: 220 GTELVDSCQASLFLLTDGEESNIESLLNKAVGLAENLQSYDPALTNVSTMLNEALIQVQE 279 E + + E+ +L + L Q + ++ L+ + ++ Sbjct: 268 ALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQ 327 Query: 280 SAGELQHYLSKLELDPAHFAYLEERLSKAMQLARKHHVSPDKLAEHHLALKSELTTLDDD 339 E Q + ++ A L L + + ++ KL E + ++ +L D Sbjct: 328 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 387 Query: 340 ENKLEDIQRQVEASKVAYLANAQ 362 + + ++QVE K AN++ Sbjct: 388 LDASREAKKQVE--KALEEANSK 408
>FLAGELLIN#Flagellin signature. Length = 507 Score = 28.5 bits (63), Expect = 0.020 Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 94 AMDAVVALSTLLGAIQTDLEEDITNISKLSSSTVANYIETISDVDLTD 141 A+ V A+ + LGAIQ + ITN+ ++ + I D D Sbjct: 427 ALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSAR-SRIEDADYAT 473
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 7e-13 Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 2/124 (1%) Query: 680 QSLTVLAVDDNFANLKLIDTLLNELVTTVIAVNSGEEAVKQAKSRTFDLIFMDIQMPGTD 739 T+L DD+ A +++ L+ V ++ + + DL+ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 740 GISATKQIRQGSMNRNTPIIAVTAHAIAEERELILGSGMDGYLPKPIDEAALKAEINRWI 799 +I+ + P++ ++A G YLPKP D L I R + Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 800 TRPK 803 PK Sbjct: 120 AEPK 123
>YERSINIAYOPE#Yersinia virulence determinant YopE protein signature. Length = 219 Score = 25.8 bits (56), Expect = 0.042 Identities = 12/70 (17%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 17 SAVTSYFHAVIRWIKQ---DQTQFGLQVFVRATAALLAGYIAAATLACMLTQVLPMSRFE 73 ++S H+VI +I++ + + + A + + + ++ + + LP + Sbjct: 61 ERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQ 120 Query: 74 -STLTANMLA 82 ++L A ML Sbjct: 121 LNSLDAEMLQ 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 3e-18 Identities = 19/116 (16%), Positives = 52/116 (44%), Gaps = 2/116 (1%) Query: 18 IRVGLVEDQQLVRQGIASLIAISQHIEVSWQAENGQEALKRLQTDAVDVLLSDIRMPVLD 77 + + +D +R + ++ + + N + + D++++D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 78 GISLLKQLRAAQNSIPVIMLTTFDDSELFLNSLQAGANGFLLKDVSLDKLLEAIET 133 LL +++ A+ +PV++++ + + + + GA +L K L +L+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 6e-07 Identities = 20/97 (20%), Positives = 44/97 (45%), Gaps = 14/97 (14%) Query: 293 LVLQEGISNAVRHG-----HANQLTLSMQEEQAELIICLKDNGQGI--SQSPSQGVGLSS 345 +++Q + N ++HG ++ L ++ + + +++ G + S G GL + Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQN 317 Query: 346 MQERLSPFHGSARLQANHAGVDSSRTQGC-SLMIRLP 381 ++ERL +G A + S QG + M+ +P Sbjct: 318 VRERLQMLYG------TEAQIKLSEKQGKVNAMVLIP 348
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 35.4 bits (81), Expect = 7e-05 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 18/125 (14%) Query: 8 KTALLIIDMQQ---GLFYADAPPFNREQVLNNINLLIANAREAGAPIWAVRHTG---PE- 60 + LLI DMQ F A A P ++ NI L + G P+ G P+ Sbjct: 30 RAVLLIHDMQNYFVDAFTAGASPV--TELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 61 --------GSPIAAGTANWQLIESLAINPQLDNIFDKTKPSCFYQTGFAEALTHEGISEL 112 G + +G ++I LA D + K + S F +T E + EG +L Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDD-DLVLTKWRYSAFKRTNLLEMMRKEGRDQL 146 Query: 113 VIVGM 117 +I G+ Sbjct: 147 IITGI 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 1e-11 Identities = 32/167 (19%), Positives = 65/167 (38%), Gaps = 3/167 (1%) Query: 2 RNAEFDRAQVLRGAMAAFMHKGYTKTSMQDLTQATGLHPGSIYCAFSNKRGLLIAAIEQY 61 + A+ R +L A+ F +G + TS+ ++ +A G+ G+IY F +K L E Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 62 QQDRDEQFKLIFSN-GRPVLGNLKTYLDNIVVECLSCDSQQACLLTKALNEIAEQDDEIQ 120 + + E + L L+ L +++ ++ + ++ + + + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126 Query: 121 NIISQNLMLWQYAL-TAQFELADSQGMLHGELNSEQRAQYLMMGIYG 166 +NL L Y + ML +L + RA +M G Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR-RAAIIMRGYIS 172
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.012 Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 6/39 (15%) Query: 339 LFGYVENATFRGTVFTDFSLIRPGSLHKANGGVLLMDAI 377 LFG+ + A FT G +A GG L +D I Sbjct: 208 LFGHEKGA------FTGAQTRSTGRFEQAEGGTLFLDEI 240
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 452 bits (1164), Expect = e-158 Identities = 172/479 (35%), Positives = 263/479 (54%), Gaps = 17/479 (3%) Query: 7 RILLVGTPSERLSRLCCIFEFLGEQIEIVAIEKLSLCLQDTRFRALVVTADNMP----AD 62 IL+ + + L G + I + LVVT MP D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 ALKSLASQYPWQPILL---FGNVDDLQVSNVLG---HIEEPLNYPQLTELLHFCQVYGQV 116 L + P P+L+ ++ G ++ +P + +L ++ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 117 KRPQVPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLVLGQSGTGKEVVARNIH 176 + ++ + LVGRS + + +++++ +D T+++ G+SGTGKE+VAR +H Sbjct: 125 RPSKLEDDSQD---GMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 177 YLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIG 236 +RR+GPF+ +N AIP +L+ESELFGHEKG+FTGA + GRFE AEGGTLFLDEIG Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 237 DMPLQMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLETMISSNEFREDLYYRLN 296 DMP+ Q +LLRVLQ+ + VGG I +DVR+VAAT++DL+ I+ FREDLYYRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 297 VFPIEMPALSERKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNL 356 V P+ +P L +R +D+P L++ V + EG RF Q A+E +K H W GNVREL NL Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENL 361 Query: 357 VERLTILYPGGLVDVNDLPVKYRHIDVPEYCVEMSEEQQERDALASIFTSEEPVEIPETR 416 V RLT LYP ++ + + R ++P+ +E + + +++ EE + Sbjct: 362 VRRLTALYPQDVITREIIENELRS-EIPDSPIEKAAARSGSLSISQAV--EENMRQYFAS 418 Query: 417 FPSELPPEGVNLKDLLAELEIDMIRQALELQDNVVARAAEMLGIRRTTLVEKMRKYGMT 475 F LPP G+ +LAE+E +I AL +AA++LG+ R TL +K+R+ G++ Sbjct: 419 FGDALPPSGL-YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.033 Identities = 26/145 (17%), Positives = 50/145 (34%), Gaps = 22/145 (15%) Query: 205 GELINLNDVIENVVANCEPIVAKHGAELAVT-NISNSLMLANVNALSSAVNNLVMNSLEA 263 ++L D + V + + + L I+ ++M V + V LV N ++ Sbjct: 213 ARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPML--VQTLVENGIKH 270 Query: 264 GATQ------IQIVASDSNEQLHLNVIDNGKGLDAKMQQKVLEPFFTTKAQGTGLGLA-V 316 G Q I + + N + L V + G + TG GL V Sbjct: 271 GIAQLPQGGKILLKGTKDNGTVTLEVENTGSL------------ALKNTKESTGTGLQNV 318 Query: 317 VQSVVRNHGGQLQLSCMPNKGCTVS 341 + + +G + Q+ +G + Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNA 343
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 465 bits (1199), Expect = e-164 Identities = 171/483 (35%), Positives = 249/483 (51%), Gaps = 43/483 (8%) Query: 1 MSEAKLLLVEDDASLREALLDTLMLAQYDCIDVASGEEAIIVLKQHQFDLVISDVQMQGI 60 M+ A +L+ +DDA++R L L A YD ++ + DLV++DV M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLGLLNYLQQHHPKLPVLLMTAYATIGSAVSAIKLGAVDYLAKPFAPEVLLNQVSRYLP 120 LL +++ P LPVL+M+A T +A+ A + GA DYL KPF L+ + R L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 LKQNSDQPVVAD-----------EKSLALLSLAQRVAASDASVMILGPSGSGKEVLARYI 169 + + D + + R+ +D ++MI G SG+GKE++AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 170 HQHSSRADEAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEI 229 H + R + FVAIN AAIP +++E+ LFG+EKGAFTGA G+FEQA+GGTL LDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 230 SEMDLGLQAKLLRVLQEREVERLGGRKTIKLDVRVLATSNRDLKAVVAAGQFREDLYYRI 289 +M + Q +LLRVLQ+ E +GGR I+ DVR++A +N+DLK + G FREDLYYR+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 290 NVFPLTWPALNQRPADILPLARHLLTKHAKALSIIDVPEFDEAACRRLLGHRWPGNVREL 349 NV PL P L R DI L RH + + K +DV FD+ A + H WPGNVREL Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEG--LDVKRFDQEALELMKAHPWPGNVREL 358 Query: 350 DNVVQRALILRSGTVITANDIIIDAQDVPLSSDD-------------------------- 383 +N+V+R L VIT I + + S Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 384 -AEYCSEPEGLGEELKAQEHVIILETLAQCQGSRKLVAEKLGISARTLRYKMARMRDMGI 442 + L E+ +IL L +G++ A+ LG++ TLR K +R++G+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGV 475 Query: 443 QLP 445 + Sbjct: 476 SVY 478
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 58.5 bits (141), Expect = 1e-14 Identities = 31/101 (30%), Positives = 54/101 (53%) Query: 12 MQSLQGEIKPSFGISPNNIVQQVNNTSGADFGQLLSQAIGNVSGLQSTSSNLSTRLEMGD 71 +Q ++G I + + Q+ F L A+ +S Q+ + + + +G+ Sbjct: 3 IQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGE 62 Query: 72 TTVSLSDTVIAREKASVAFEATVQVRNKLVEAYKEIMSMPV 112 V+L+D + +KASV+ + +QVRNKLV AY+E+MSM V Sbjct: 63 PGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 299 bits (766), Expect = 1e-96 Identities = 158/560 (28%), Positives = 270/560 (48%), Gaps = 43/560 (7%) Query: 26 LGGVDMMRQITMILALAICLALAVFVMIWAQEPEYRPL-GKMETQEMVQVLDVLDKNKIK 84 L + +I +I+A + +A+ V +++WA+ P+YR L + Q+ ++ L + I Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 85 YQIEVD--VVKVPEDKYQEVKMMLSRAGVNSPAASTQDFLTQDSGFGVSQRMEQARLKHS 142 Y+ ++VP DK E+++ L++ G+ A + L Q FG+SQ EQ + + Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQ-EKFGISQFSEQVNYQRA 134 Query: 143 QEENLARAIEQLQSVSRAKVILALPKENVFARNTSQPSATVVINTRRG-GLGQGEVDAIV 201 E LAR IE L V A+V LA+PK ++F R PSA+V + G L +G++ A+V Sbjct: 135 LEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVV 194 Query: 202 DIVASAVQGLEPSRVTVTDSNGRLLNSGSQDGISARARRELELVQQKEAEYRTKIDSILS 261 +V+SAV GL P VT+ D +G LL + G +L+ E+ + +I++ILS Sbjct: 195 HLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDL-NDAQLKFANDVESRIQRRIEAILS 253 Query: 262 PILGPDNFTSQVDVSMDFTAVEQTAKRFNPDLPSLRSEMTVENNST-----GGSTGGIPG 316 PI+G N +QV +DF EQT + ++P+ + ++ + + G GG+PG Sbjct: 254 PIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPG 313 Query: 317 ALSNQPP---------------MESNIPQDAT-KATESVTAGNSHREATRNFELDTTISH 360 ALSNQP N PQ +T + S ++ R T N+E+D TI H Sbjct: 314 ALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSNYEVDRTIRH 373 Query: 361 TRQQIGVVRRVSVSVAVDFKPGAAGENGQVARVARTEQELTNIRRLLEGAVGFSAQRGDV 420 T+ +G + R+SV+V V++K A G+ + T ++ I L A+GFS +RGD Sbjct: 374 TKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIEDLTREAMGFSDKRGDT 428 Query: 421 LEVVTVPFMDQLVEDVPAPELWEQPWFWRAVKLGIGALVILVLILAVVRPMLKRLIYPDS 480 L VV PF + W+Q F + L L+L V + ++ + P Sbjct: 429 LNVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWL----LVLVVAWILWRKAVRPQL 483 Query: 481 VNMPEDSRLGNELAEIEDQYAADTLGMLNTKEAEYSYADDGSILIPNLHKDDDMIKAIRA 540 E+++ E A++ + L+ + E + + + M + IR Sbjct: 484 TRRVEEAKAAQEQAQVRQETEEAVEVRLS--KDEQLQQRRANQRLGA----EVMSQRIRE 537 Query: 541 LVANEPELSTQVVKNWLQDN 560 + N+P + V++ W+ ++ Sbjct: 538 MSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 290 bits (745), Expect = 4e-99 Identities = 109/348 (31%), Positives = 194/348 (55%), Gaps = 5/348 (1%) Query: 1 MAENKSKDAAETSSFNIKDLSGIEKTAILLLSLSEADAASILKHLEPKQVQKVGMAMAAM 60 M E K K+ + + L+G +K AILL+S+ ++ + K+L ++++ + +A + Sbjct: 1 MEEKKEKEILD-----VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKL 55 Query: 61 EDFGQEKVIGVHKLFLDDIQKYSSIGFNSEEFVRKALTAALGEDKAGNLIEQIIMGSGAK 120 E E V F + + I ++ R+ L +LG KA ++I + ++ Sbjct: 56 ETITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSR 115 Query: 121 GLDSLKWMDARQVATIIQNEHPQIQTIVLSYLEPDQAAEIFGQFPENTRLDLMMRIANLE 180 + ++ D + IQ EHPQ ++LSYL+P +A+ I P + ++ RIA ++ Sbjct: 116 PFEFVRRADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMD 175 Query: 181 EVQPAALQELNDIMEKQFAGQGGAQAAKMGGLKAAANIMNYLDTGVESQLMETMRETDEE 240 P ++E+ ++EK+ A GG+ I+N D E ++E++ E D E Sbjct: 176 RTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPE 235 Query: 241 MAQQIQDLMFVFENLIDVDDRGIQTLLREVQQDVLMKALKGADDQLKDKILGNMSKRAAE 300 +A++I+ MFVFE+++ +DDR IQ +LRE+ L KALK D +++KI NMSKRAA Sbjct: 236 LAEEIKKKMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAAS 295 Query: 301 LLRDDLEAMGPIRISEVEIAQKEILSIARRLSDSGEIMLGGGGGDEFL 348 +L++D+E +GP R +VE +Q++I+S+ R+L + GEI++ GG ++ L Sbjct: 296 MLKEDMEFLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 91.4 bits (226), Expect = 8e-24 Identities = 59/203 (29%), Positives = 106/203 (52%), Gaps = 9/203 (4%) Query: 48 YSPQQAPKAVAAETIAPPTMAEIEDIRAQAEEEGFNEGKTQGYAEGLEQGRLEGLEQGHT 107 + P P+ E P ++ ++ QA E QGY G+ +GR +G +QG+ Sbjct: 22 FVPIVEPEETIIEEAEPSLEQQLAQLQMQAHE--------QGYQAGIAEGRQQGHKQGYQ 73 Query: 108 EGLAQGHEQGLEAGLAEAKALVSRFEGLLSQFEKPLQLLDGDIEHSLMTLTMALAKSVIG 167 EGLAQG EQGL ++ + +R + L+S+F+ L LD I LM + + A+ VIG Sbjct: 74 EGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIG 133 Query: 168 HELKTHPEQILSALRLGVESLPIKEQSVSIRMHPDDVALVEQLYSSTQLNRNQWQLEADP 227 ++ ++ ++ P+ +R+HPDD+ V+ + +T L+ + W+L DP Sbjct: 134 QTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT-LSLHGWRLRGDP 192 Query: 228 SLNSGDCIISSQRSLVDLTLSSR 250 +L+ G C +S+ +D ++++R Sbjct: 193 TLHPGGCKVSADEGDLDASVATR 215
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 44.0 bits (103), Expect = 2e-08 Identities = 37/145 (25%), Positives = 71/145 (48%) Query: 1 MANADPLLLVLKLALDAEEQAALLLKSAQLECQKRQNQLDALNNYRLDYMKQMQSQQGQA 60 MA L + LA E AA LL + CQ+ + QL L +Y+ +Y + S Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ISASHYHQFHRFIRQIDEAIAQQNRVVADGEKQKNYRQQHWLEKQKKRKAVELLLDNKEK 120 I+++ + + +FI+ +++AI Q + + ++ + W EK+++ +A + L + + Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 KRQALELKKEQKMTDEFASQQFFRR 145 E + +QK DEFA + R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 53.7 bits (128), Expect = 8e-10 Identities = 49/198 (24%), Positives = 83/198 (41%), Gaps = 17/198 (8%) Query: 387 VAALSSGSEEADSEFKPVEFKAVPSLHSLATPATQRQDIPQVQLSLRQGVETQNQMQEMI 446 + A + E S PV A P + Q Q +P V + ++ Q+ Sbjct: 190 LVAEAQSKAEVISTPSPVTAAASPLITP-----HQTQPLPTVAAPVLSAPLGSHEWQQ-- 242 Query: 447 QRFSPVMKQQLVTMVSQGIQQAEIRLDPPELGHMLVKVQVHGDQTQVQFHVTQSQTRDVV 506 + Q + QG Q AE+RL P +LG + + ++V +Q Q+Q R + Sbjct: 243 -----SLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAAL 297 Query: 507 EQAIPRLRELLQEQGMQLADSHVSQGDHGQRREGGFGEAGGSSGGNVDDFSAEELD---- 562 E A+P LR L E G+QL S++S +++ + N + + E+ D Sbjct: 298 EAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPV 357 Query: 563 -LGLNQATSLNSGIDYYA 579 + L + NSG+D +A Sbjct: 358 PVSLQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 249 bits (636), Expect = 7e-83 Identities = 88/327 (26%), Positives = 165/327 (50%), Gaps = 12/327 (3%) Query: 1 MSDLLSQDEIDALLHGVDDVEEDNELDAAGLEARS----YDFSSQDRIVRGRMPTLEIVN 56 M+++LSQDEID LL + + E DA + YDF D+ + +M TL +++ Sbjct: 1 MTEVLSQDEIDQLLTAISSGDASIE-DARPISDTRKITLYDFRRPDKFSKEQMRTLSLMH 59 Query: 57 ERFARHLRISMFNMMRRAAEVSINGVQMLKFGEYVHTLFVPTSLNMVRFHPLKGTALITM 116 E FAR S+ +R V + V L + E++ ++ P++L ++ PLKG A++ + Sbjct: 60 ETFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEV 119 Query: 117 EARLVFILVDNFFGGDGRFHAKIEGREFTPTERRIVQLLLKIIFEDYKDAWAPVMDVEFD 176 + + F ++D FGG G+ R+ T E +++ ++ I + +++W V+D+ Sbjct: 120 DPSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPR 177 Query: 177 YLDSEVNPAMANIVSPTEVVVINSFHIEVDGGGGDFHITMPYSMIEPIRELLDAG--VQS 234 E NP A IV P+E+VV+ + +V G + +PY IEPI L + S Sbjct: 178 LGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSS 237 Query: 235 DKQDTDMRWSQALHDEIMDVKVGFDASVVEHELTLKDVMNFKAGDIIPIE---LPEYIMM 291 ++ + ++ L D++ V + A V L+++D++ + GDII + + + ++ Sbjct: 238 VRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVL 297 Query: 292 KIEDLPTYRCKMGRSRDNLALKIYEKI 318 I + + C+ G +A +I E+I Sbjct: 298 SIGNRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 111 bits (279), Expect = 6e-35 Identities = 54/122 (44%), Positives = 81/122 (66%) Query: 2 STDDDWAAAMAEQALEEANAIDLDELVDESQPISKAEAAKLDTILDIPVTISMEVGRSYI 61 + DD WA A+ EQ + +D I+DIPV +++E+GR+ + Sbjct: 14 ALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRM 73 Query: 62 SIRNLLQLNQGSVVELDRVAGEPLDVMVNGTLIAHGEVVVVNDKFGIRLTDVISQTERIK 121 +I+ LL+L QGSVV LD +AGEPLD+++NG LIA GEVVVV DK+G+R+TD+I+ +ER++ Sbjct: 74 TIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMR 133 Query: 122 KL 123 +L Sbjct: 134 RL 135
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 276 bits (707), Expect = 2e-96 Identities = 121/240 (50%), Positives = 175/240 (72%) Query: 8 FIGVSTLLFAASVGAADGVLPAVTVKTAADGSTEYSVTMQILLLMTSLSFIPAMVIMLTS 67 + V+ +L A LP +T + G +S+ +Q L+ +TSL+FIPA+++M+TS Sbjct: 4 LLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTS 63 Query: 68 FTRIIVVLSILRQAIGLQQTPSNQVLIGMSLFMTFFIMAPVFDKIYDQGVKPYIDEQLTL 127 FTRII+V +LR A+G P NQVL+G++LF+TFFIM+PV DKIY +P+ +E++++ Sbjct: 64 FTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISM 123 Query: 128 QQAFDKGKEPLRAFMLGQVRTTDLKTFIDISGYQNINSPEEAPMSVLVPAFITSELKTAF 187 Q+A +KG +PLR FML Q R DL F ++ + PE PM +L+PA++TSELKTAF Sbjct: 124 QEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAF 183 Query: 188 QIGFMLFVPFLVLDLVVASILMAMGMMMLSPMIVSLPFKIMLFVLVDGWGLVMGTLANSF 247 QIGF +F+PFL++DLV+AS+LMA+GMMM+ P ++LPFK+MLFVLVDGW L++G+LA SF Sbjct: 184 QIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 47.1 bits (112), Expect = 1e-10 Identities = 20/73 (27%), Positives = 39/73 (53%) Query: 4 EALIDIFREALAVIVMMVSAIVLPGLGIGLIVAVFQAATSINEQTLSFLPRLIVTLLALM 63 + L+ +AL +++++ + IGL+V +FQ T + EQTL F +L+ L L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VMGHWLVQTLMDF 76 ++ W + L+ + Sbjct: 62 LLSGWYGEVLLSY 74
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 123 bits (310), Expect = 4e-36 Identities = 94/243 (38%), Positives = 142/243 (58%), Gaps = 1/243 (0%) Query: 15 YMWPLFRVTSMLMVMVVFGATTTPTRVRLLLAVTITLAIAPVLPPVKDAELFSLSAVFIT 74 Y WPL RV +++ + + P RV+L LA+ IT AIAP LP D +FS A+++ Sbjct: 16 YFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLP-ANDVPVFSFFALWLA 74 Query: 75 AQQIIIGVAMGFVTQMVMQTFVLTGQIIGMQTSLGFASMVDPGSGQQTPVIGNFFLLLAT 134 QQI+IG+A+GF Q G+IIG+Q L FA+ VDP S PV+ +LA Sbjct: 75 VQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLAL 134 Query: 135 LIFLAVDGHLLMIRMLVASFETLPISNQGLTLTSYRSLAEWGSYMFGAALTMSLSAIIAL 194 L+FL +GHL +I +LV +F TLPI + L ++ +L + GS +F L ++L I L Sbjct: 135 LLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLITLL 194 Query: 195 LLVNLSFGVMTRAAPQLNIFSIGFPITMIGGLLILWLTLTPVMAHFEEVWASAQLLLCDI 254 L +NL+ G++ R APQL+IF IGFP+T+ G+ ++ + + E +++ LL DI Sbjct: 195 LTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254 Query: 255 LGL 257 + Sbjct: 255 ISE 257
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 337 bits (866), Expect = e-117 Identities = 98/347 (28%), Positives = 178/347 (51%), Gaps = 2/347 (0%) Query: 6 SGERSEEPTGRRLEQAREKGQVARSKELGTATVLLSAATGLYMLGPGIAKALSNVFERVF 65 SGE++E+PT +++ AR+KGQVA+SKE+ + ++++ + L L + S + + Sbjct: 2 SGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LI 59 Query: 66 TMERAAIFDTNQMFNVWGVVGSEIGWPLLKIMLLIVVVAFIGNVSLGGMNFSTQAMMPKA 125 E++ + + + V V E + ++ + ++A +V G S +A+ P Sbjct: 60 PAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 126 SKMSPIAGFKRMFGVQALVELTKGIAKFSVVAIAAYLLLSHYFNDILLLSADHLPGNVHH 185 K++PI G KR+F +++LVE K I K +++I ++++ +L L + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 186 ALDLLVWMFILLCSSVLVIVVIDVPFQIWNHNKQLKMTKQEVKDEYKDTEGKPEVKGRVR 245 +L + ++ +VI + D F+ + + K+LKM+K E+K EYK+ EG PE+K + R Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 246 QMQRELAQRRMMAEVPNADVIVVNPEHYAVAIKYDVKRSAAPFVIAKGVDEVAFKIREVA 305 Q +E+ R M V + V+V NP H A+ I Y + P V K D +R++A Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 306 RAHNIAIVSAPPLARAIYHTTKLEQQIPEGLFTAVAQVLAYVFQLRQ 352 + I+ PLARA+Y ++ IP A A+VL ++ + Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.026 Identities = 25/158 (15%), Positives = 51/158 (32%), Gaps = 19/158 (12%) Query: 485 VVDAATVVATHISQILTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDV-MPLGNVVK 543 V D + T ++Q L+ + L +A LV + DV MP N Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLV---VTDVVMPDENAFD 64 Query: 544 VMQNLLNEGVSVR--------DLRTIVQTL----LEYGTKSNDTEVLTAAVRIAL---KR 588 ++ + + T ++ +Y K D L + AL KR Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 589 MIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGP 626 + + +P++ + ++++ + D Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.013 Identities = 9/25 (36%), Positives = 12/25 (48%) Query: 238 VKQGGVVALVGPTGVGKTTSLAKLA 262 K V L G G+GK+T + L Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLV 617
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 3e-24 Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFNNTQEADDGSTALPMLQKGDFDFVVTDWNMPGMQGI 65 IL+ DD + +R ++ L G++ + +T + GD D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLKAIRADDSLKHLPVLMVTAEAKREQIIAAAQAGVNGYVVKPF 110 DLL I+ LPVL+++A+ I A++ G Y+ KPF Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF06580#Sensor histidine kinase Length = 349 Score = 45.6 bits (108), Expect = 4e-07 Identities = 28/182 (15%), Positives = 54/182 (29%), Gaps = 68/182 (37%) Query: 454 TLNKEIDLVLV---------GEETDLDKNLVEALADPLVH------LVRNSVDHGIEMPN 498 +L E+ +V + + + A+ D V LV N + HGI Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA--- 273 Query: 499 DREASGKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDEDTAARMTD 558 P+ G I L +++ + L++E+ G+ Sbjct: 274 -----QLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------------- 306 Query: 559 SEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNG---TVHIDSMKGKGTVLEIK 615 G G+ V+ R+ L G + + +GK + + Sbjct: 307 -------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VL 346 Query: 616 VP 617 +P Sbjct: 347 IP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 1e-13 Identities = 28/135 (20%), Positives = 56/135 (41%), Gaps = 7/135 (5%) Query: 2 AIKVLVVDDSSFFRRRVSEIVNQDPELEVIATASNGAEAVKMAAELNPQVITMDIEMPVM 61 +LV DD + R +++ +++ + SN A + A + ++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVREIMAKCP-TPILMFSSLTHDGAKATLDALDAGALDFLPKRF--EDIATNKDEA 118 + + I P P+L+ S+ + + A + GA D+LPK F ++ A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSA--QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 ILLLQQRVKALGRRR 133 + ++R L Sbjct: 119 LAEPKRRPSKLEDDS 133
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 172 bits (438), Expect = 5e-50 Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 10/217 (4%) Query: 142 TTPWGQTFVGATQLSDSQAG-NRTICIIDSGYDRGHSDLSGNNVTGTN--NSGTGNWYEP 198 P G + A + + G + ++D+G D H DL + G N + G+ Sbjct: 21 EIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIF 80 Query: 199 GNNNAHGTHVAGTIAAIANNDGVIGVMPNQNANIHVIKVFNEAGWGYSSSLVSAVDTCVA 258 + N HGTHVAGTIAA N +GV+GV P A++ +IKV N+ G G ++ + + Sbjct: 81 KDYNGHGTHVAGTIAATENENGVVGVAPE--ADLLIIKVLNKQGSGQYDWIIQGIYYAIE 138 Query: 259 NGANVVTMSLGGAGSSTTERNALAAHYNNGVLLIAAAGNDG-----NNTHSYPASYDAVM 313 ++++MSLGG A+ + +L++ AAGN+G + YP Y+ V+ Sbjct: 139 QKVDIISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVI 198 Query: 314 SVASVDNHKDHSAFSQYTNQVEISGPGEAILSTVTRG 350 SV +++ + S FS N+V++ PGE ILSTV G Sbjct: 199 SVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGG 235 Score = 67.9 bits (166), Expect = 3e-14 Identities = 28/146 (19%), Positives = 50/146 (34%), Gaps = 16/146 (10%) Query: 431 NAVKACKNAGASAVIVYSNSALPGLQNPFLVDANSEINMVSV-SVDRATGLALRNQLGAT 489 AVK + + N + L ++SV +++ + + Sbjct: 159 EAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNE 218 Query: 490 VTVSNQG--------NKDYEYYNGTSMATPHVSGVATLVWS-----YHPECSAAQVRNAL 536 V + G Y ++GTSMATPHV+G L+ + + + ++ L Sbjct: 219 VDLVAPGEDILSTVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQL 278 Query: 537 KQTAEDLGTAGRDDYYGYGLVNAVAA 562 + LG G GL+ A Sbjct: 279 IKRTIPLG--NSPKMEGNGLLYLTAV 302
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.0 bits (59), Expect = 0.024 Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 52 DVRTPEEFAEGHLANAVNIPFEQVAAEFAKRGIAKDA 88 D+ + E + A +N+P E V EF K GI +D+ Sbjct: 407 DILACDRLPEPNPAEDLNLPSETVNVEFQKSGIFQDS 443
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 487 bits (1254), Expect = e-157 Identities = 219/1066 (20%), Positives = 427/1066 (40%), Gaps = 79/1066 (7%) Query: 29 LLALLGLLLGLFAILVTPKEEEPQIDVTFADVFIPFPGATPTEVENLVTLPAEQVISELK 88 +LA++ ++ G AIL P + P I V +PGA V++ VT EQ ++ + Sbjct: 14 VLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGID 73 Query: 89 GIDTLYSFSQPDG-AMIIVIFKVGVTRNDAIVSLYNQIYSNMDKLPQGAGVGEPLIKPRG 147 + + S S G I + F+ G + A V + N++ LPQ V + I Sbjct: 74 NLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE--VQQQGISVEK 131 Query: 148 IDDVPIVSLTLWSKDKQVSAEQLTHLA-LGLETEIKRIPGTREIYTVGQHEMVANVRIDP 206 ++ S + + + ++ ++ + R+ G ++ G + + +D Sbjct: 132 SSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMR-IWLDA 190 Query: 207 AKMNSFNLTYDKLRQSLNDNN------HISMPASLVQGNQEIKVQAGQFLQSIDDVKQLV 260 +N + LT + L N + +L + A ++ ++ ++ Sbjct: 191 DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVT 250 Query: 261 VSISQDKQGKPIPVYLADTADISLKSDIPTQSVWHSDKTDIYPAVTIAIGKQPGQNAVDI 320 + ++ D V L D A + L + + K PA + I G NA+D Sbjct: 251 LRVNSDGS----VVRLKDVARVELGGENYNVIARINGK----PAAGLGIKLATGANALDT 302 Query: 321 ADATLARIAKVKNVLIPSNVEVTVSRNYGETAADKSNTLILKLIFATSAVVVLVFLTMGA 380 A A A++A+++ P ++V + + ++ L A V ++++L + Sbjct: 303 AKAIKAKLAELQPFF-PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 381 -RESLVVGVAIIITLAITLFASWAWGFTLNRVSLFALIFSIGILVDDAIVVVENIHRHMA 439 R +L+ +A+ + L T A+G+++N +++F ++ +IG+LVDDAIVVVEN+ R M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 440 LGKKSFSELIPVAVDEVGGPTILATFTVIAALLPMAFVSGLMGPYMSPIPINASMGMLIS 499 K E ++ ++ G + + A +PMAF G G I M +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 500 LVVAFMVTPWLSRKLLKHHSGSATNTAHSSDADAQMNESKMVRLFTRLIGPFLLGKGARK 559 ++VA ++TP L LLK S V +T +G L Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKIL----GST 537 Query: 560 ARIGLAAGVFVLIGIAVALPVGQLVVLKMLPFDNKSEFQVMVDMPEGTPVEQTQRVLQDL 619 R L + V + + L + LP +++ F M+ +P G E+TQ+VL + Sbjct: 538 GRYLLIYALIVAGMVVLFLRLPS----SFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 620 SRYLATVPEVEHLQLYAGTNAPMNFNGLVRHYFLRHSQELGDIQVNLVDKKHRKRDSHSI 679 + Y + ++ T +F+G +Q G V+L + R D +S Sbjct: 594 TDYYLKNEKANVESVF--TVNGFSFSGQ--------AQNAGMAFVSLKPWEERNGDENSA 643 Query: 680 ALSVREELQHIGAKYQANVKVVEVPPGPPVWSPIVAEVYGPSPAIREQAAYELQSLFRET 739 + +G V P + A G + +QA +L + Sbjct: 644 EAVIHRAKMELGKIRDGF---VIPFNMPAIVELGTAT--GFDFELIDQAGLGHDALTQAR 698 Query: 740 KDVVDIDIFLPAA-----------QQKWQVMIDRSKASLMAVPYSNIVDLIATSVGGKDV 788 ++ + PA+ ++++ +D+ KA + V S+I I+T++GG V Sbjct: 699 NQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYV 758 Query: 789 SYLHIAQQKQPVPIRLQLQEGAKIDLEQVLNMKLQSQTGQSVPVSELVTIKRGKIDAPII 848 + + + + +Q ++ E V + ++S G+ VP S T + Sbjct: 759 N--DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLE 816 Query: 849 HKNMIPMVMVVADMAGPLDSPLYGMFDMAGKIDGEGGLGFDQHYIHQPTGLDSVAVLWDG 908 N +P + + G G+ + P G + W G Sbjct: 817 RYNGLPSMEIQG-------------EAAPGTSSGDAMALMENLASKLPAG---IGYDWTG 860 Query: 909 EWKITYETFRDMGIAYAVGMIAIYLLVVAQFRSYLVPLIIMAPIPLTVIGVMPGHALLGA 968 + A+ + ++L + A + S+ +P+ +M +PL ++GV+ L Sbjct: 861 MSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQ 920 Query: 969 QFTATSMIGMIALAGIIVRNSILLVDFINQ-ETASGVPFERAVIHSGAVRAKPIMLTALA 1027 + M+G++ G+ +N+IL+V+F G A + + +R +PI++T+LA Sbjct: 921 KNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLA 980 Query: 1028 AMIGALFILDDP-----IFNGLAISLIFGIFISTLLTLIVIPVLYY 1068 ++G L + N + I ++ G+ +TLL + +PV + Sbjct: 981 FILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 75.6 bits (186), Expect = 8e-16 Identities = 83/518 (16%), Positives = 180/518 (34%), Gaps = 46/518 (8%) Query: 15 GRIAAAFQNSAITPLLALLGLLLGLFAI-LVTPKEEEPQIDVTFADVFIPFPGATPTEVE 73 S LL ++ G+ + L P P+ D I P E Sbjct: 527 TNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERT 586 Query: 74 NLVTLPAEQVI--SELKGIDTLYSFSQ-------PDGAMIIVIFK---VGVTRNDAIVSL 121 V +E ++++++ + + M V K ++ ++ Sbjct: 587 QKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 122 YNQIYSNMDKLPQGAGVGEPLIKPRGIDDVPIVSLTLWSKDKQ-VSAEQLTHLALGLETE 180 ++ + K+ G P P ++ D+ + + LT L Sbjct: 647 IHRAKMELGKIRDG--FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 181 IKRIPGTREIYTVGQHEMVA--NVRIDPAKMNSFNLTYDKLRQSLNDNNHISMPASLVQG 238 + P + E A + +D K + ++ + Q+++ + + Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 239 NQEIKV---QAGQFLQSIDDVKQLVVSISQDKQGKPIPVYLADTADISLKSDIPTQSVWH 295 + K+ +F +DV +L V G+ +P + + Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRS---ANGEMVP--FSAFTTSHWVYG-SPRLE-- 816 Query: 296 SDKTDIYPAVTIAIGKQPGQNAVDIADATLARIAKVKNVLIPSNVEVTVSRNYGETAADK 355 + + P++ I PG DA +A + + + L P+ + + G + ++ Sbjct: 817 --RYNGLPSMEIQGEAAPG---TSSGDA-MALMENLASKL-PAGIGYDWT---GMSYQER 866 Query: 356 SNTLILKLIFATSAVVVLVFLTMGAR-ESLVVGVAIIITLAIT----LFASWAWGFTLNR 410 + + A S V+VFL + A ES + V++++ + + L A+ + + Sbjct: 867 LSGNQAPALVAIS--FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV 924 Query: 411 VSLFALIFSIGILVDDAIVVVENIHRHMALGKKSFSELIPVAVDEVGGPTILATFTVIAA 470 + L+ +IG+ +AI++VE M K E +AV P ++ + I Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 471 LLPMAFVSGLMGPYMSPIPINASMGMLISLVVAFMVTP 508 +LP+A +G + + I GM+ + ++A P Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVP 1022 Score = 59.1 bits (143), Expect = 8e-11 Identities = 35/166 (21%), Positives = 76/166 (45%), Gaps = 10/166 (6%) Query: 915 ETFRDMGIAYAVGMIAIYLLVVAQFRSYLVPLIIMAPIPLTVIGVMPGHALLGAQFTATS 974 E + + A + + +YL + R+ L+P I +P+ ++G A G + Sbjct: 339 EVVKTLFEAIMLVFLVMYL-FLQNMRATLIPTIA---VPVVLLGTFAILAAFGYSINTLT 394 Query: 975 MIGMIALAGIIVRNSILLVDFINQETAS-GVPFERAVIHS-----GAVRAKPIMLTALAA 1028 M GM+ G++V ++I++V+ + + +P + A S GA+ ++L+A+ Sbjct: 395 MFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFI 454 Query: 1029 MIGALFILDDPIFNGLAISLIFGIFISTLLTLIVIPVLYYAAMKNR 1074 + I+ +I+++ + +S L+ LI+ P L +K Sbjct: 455 PMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPV 500
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 8e-06 Identities = 38/259 (14%), Positives = 76/259 (29%), Gaps = 66/259 (25%) Query: 75 AALLEITSKEQGAELASYEADLAKATALNVEAQAQYKRYKELFPQGAISK---------- 124 E+ ++ AE + A + + L+ +++ + L + AI+K Sbjct: 202 KYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKY 261 Query: 125 ----GAMDEATANAKAAEQAVSAAKARVI-----------------------------KA 151 + + + E + +AK K Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 152 TESLKYTVVSAPFSGIVTERLV-ELGETVSVGQPLLSGFSPSQ--MRAITQVPQRYIQQL 208 E + +V+ AP S V + V G V+ + L+ P + V + I + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV-IVPEDDTLEVTALVQNKDIGFI 380 Query: 209 KNAPEFMVRLS--DGRE---LTSKDLTIFSFADPVSH-----SYQVRINLPKDEP----- 253 ++++ L K I D + + V I++ ++ Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNI--NLDAIEDQRLGLVFNVIISIEENCLSTGNK 438 Query: 254 --NLQPGTWAKALFKNGER 270 L G A K G R Sbjct: 439 NIPLSSGMAVTAEIKTGMR 457 Score = 30.6 bits (69), Expect = 0.009 Identities = 18/75 (24%), Positives = 26/75 (34%), Gaps = 1/75 (1%) Query: 159 VVSAPFSGIVTERLVELGETVSVGQPLLSGFSPSQMRAITQVPQRYIQQLKNAPEFMVRL 218 + + IV E +V+ GE+V G LL + A T Q + Q + L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLK-LTALGAEADTLKTQSSLLQARLEQTRYQIL 156 Query: 219 SDGRELTSKDLTIFS 233 S EL Sbjct: 157 SRSIELNKLPELKLP 171
>PF06580#Sensor histidine kinase Length = 349 Score = 27.9 bits (62), Expect = 0.042 Identities = 15/103 (14%), Positives = 35/103 (33%), Gaps = 7/103 (6%) Query: 21 GFGLIKRKGLRTFVFIPLMINLVLFAAVIYVAIGQLDVLFTWMNAQLPEYLSWLNF---- 76 G+G+ L F F L + L + + +AI + ++ T + WL Sbjct: 19 GWGVY---TLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQ 75 Query: 77 LLWPLAVTTMLVMLAFVFSSVMNWLAAPFNGLLAEKVEQLLTG 119 ++ + +++ + + ++ W F L Sbjct: 76 IILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLAL 118
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 46.6 bits (110), Expect = 5e-07 Identities = 42/293 (14%), Positives = 104/293 (35%), Gaps = 9/293 (3%) Query: 616 AKQDNSQSLVQLSKEQTQLSEAIAECEQAKAIQQAKLDELAQQLTQVRDSLSQGTKRLHQ 675 A + + +L ++ + + + + L ++ + LS ++L + Sbjct: 44 ATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRK 103 Query: 676 LQLDKATKSTQLNNAEAQAKQREAKRGQLAETVARTQAELAELAEQLMLLAEQEDELAEA 735 + K++++ EA+ E A++ L + LA ++ +L +A Sbjct: 104 NDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKA 163 Query: 736 LEVSLEQQQQQSQDAQGDMARHQALKAQIGDAERRLASLNASLQSVTTRMAVSTEQIELQ 795 LE ++ S + A AL+A+ + E+ L + + ++ + Sbjct: 164 LEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAAL 223 Query: 796 RVRVSELVHSKETLSA--QLANVAAQEGDQQTVQLSEQLAQLLNQQQGQQQALKSLRSQQ 853 R ++L + E + + + + L + A+L +G + ++ Sbjct: 224 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 854 SSLTETLNSIGLKQKQELGKLEGLTQSLSTLKLRREGLKGQADSQLAALSEQQ 906 +L + E LE +Q L+ R+ L+ D+ A + + Sbjct: 284 KTLEAEKA----ALEAEKADLEHQSQVLNA---NRQSLRRDLDASREAKKQLE 329 Score = 43.1 bits (101), Expect = 6e-06 Identities = 30/182 (16%), Positives = 69/182 (37%), Gaps = 7/182 (3%) Query: 188 RENLERLGDIRSELAKQLEKLSQQAKAAKQYRELKQAERKTHAELLVMRYQELQSQMASL 247 + +LE+ + + + +A K E +QAE + E + +++ +L Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 248 SEQISSLELQQAAAQSLAQTGELESTELQLKLSQLAEQEQQAVEAYYLTGTEIAKLEQQL 307 + ++L ++A + + ST K+ L ++ A+LE+ L Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA-------RQAELEKAL 269 Query: 308 QSQKQRDAQLHNQLEQLSEQIIQNQAKLAAYQASFQALEAELSQLAPQHELQQEMMDELQ 367 + +++ L + +A+ A + Q L A L + +E +L+ Sbjct: 270 EGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLE 329 Query: 368 AQ 369 A+ Sbjct: 330 AE 331 Score = 42.7 bits (100), Expect = 8e-06 Identities = 58/361 (16%), Positives = 131/361 (36%), Gaps = 30/361 (8%) Query: 146 QGTISRLIESKPQDLRTFIEEAAGISRYKERRRETENRIRHTRENLERLGDIRSELAKQL 205 +S E ++ ++ E+A+ I + R+ + E + L + Sbjct: 91 TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150 Query: 206 EKLSQQAKAAKQYRELKQAERKTHAELLVMRYQELQSQMASLSEQISSLELQQAAAQSLA 265 L+ + ++ E + + + L+++ A+L + + LE A + + Sbjct: 151 AALAARKADLEKALEGAMNFSTADSA----KIKTLEAEKAALEARQAELEKALEGAMNFS 206 Query: 266 QTGELESTELQLKLSQLAEQEQQAVEAYYLTGTEIAKLEQQLQSQKQRDAQLHNQLEQLS 325 + L+ + + LA ++ +A ++++ + A L + +L Sbjct: 207 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 266 Query: 326 EQIIQNQAKLAAYQASFQALEAELSQLAPQHELQQEMMDELQAQWEMSVSRSEAQSESAR 385 + + A A + LEAE + L + ++ + Q A +S R Sbjct: 267 KALEGAMNFSTADSAKIKTLEAEKAALE---AEKADLEHQSQV--------LNANRQSLR 315 Query: 386 VLAAAVAQHKLQLELHRSKLAHQQQLNAHKTQLHQEQQQELASLNAHALEDNSASLNDEI 445 A + K QLE KL Q +++ Q +L + + + Sbjct: 316 RDLDASREAKKQLEAEHQKLEEQNKISEASRQ---------------SLRRDLDASREAK 360 Query: 446 TQLEQALAEQVEINQGFESTLAAVTHTLDVARGEFEQLSQRLTSMRARFELVEQWLAKQE 505 QLE + E N+ E++ ++ LD +R +Q+ + L ++ +E+ + E Sbjct: 361 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELE 420 Query: 506 E 506 E Sbjct: 421 E 421 Score = 42.0 bits (98), Expect = 1e-05 Identities = 47/282 (16%), Positives = 93/282 (32%), Gaps = 11/282 (3%) Query: 231 ELLVMRYQELQSQMASLSEQISSLELQQAAAQSLAQTGELESTELQLK---LSQLAEQEQ 287 L ++ +L +L + L + + A+ + + +E K L + Sbjct: 67 NTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLE 126 Query: 288 QAVEAYYLTGTEIAKLEQQLQSQKQRDAQLHNQLEQLSEQIIQNQAKLAAYQASFQALEA 347 +A+E T + + L+++K A LE+ E A A + LEA Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGA---MNFSTADSAKIKTLEA 183 Query: 348 ELSQLAPQHELQQEMMDELQAQWEMSVSRSEAQSESARVLAAAVAQHKLQLELHRSKLAH 407 E + L + ++ ++ ++ + LAA A + LE + Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 243 Query: 408 QQQLNAHKTQLHQEQQQELASLNAHALEDNSASLNDEITQLEQALAEQVEINQGFESTLA 467 + A L ALE + +++ AE+ + A Sbjct: 244 DSAKIKTLEAEKAALEARQAELEK-ALEGAMNFSTADSAKIKTLEAEKAALEA----EKA 298 Query: 468 AVTHTLDVARGEFEQLSQRLTSMRARFELVEQWLAKQEELSD 509 + H V + L + L + R + +E K EE + Sbjct: 299 DLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNK 340 Score = 34.3 bits (78), Expect = 0.003 Identities = 58/390 (14%), Positives = 124/390 (31%), Gaps = 28/390 (7%) Query: 430 NAHALEDNSASLNDEITQLEQALAEQVEINQGFESTLAAVTHTLDVARGEFEQLSQRLTS 489 +++ + E L+ ++ N+ + +T L A+ + + + L+ Sbjct: 51 TLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSE 110 Query: 490 MRARFELVEQWLA------------KQEELSDKPQLWQSIQVENGWEAAAELALQGLMTL 537 ++ + +E A + + L +A E AL+G M Sbjct: 111 KASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 170 Query: 538 PVGVNANEIGFYADAALSADVHLDGSPILDAKLNLAPWLKGLKWADNLASAQAQLPSLAA 597 +A A+ A + L+ +N + + + + +A+ +LAA Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFS-----TADSAKIKTLEAEKAALAA 225 Query: 598 DERIVTADGYLLGKGFLIAKQDNSQSLVQLSKEQTQLSEAIAECEQAKAIQQAKLDELAQ 657 + + A + S + L A E +A + L+ Sbjct: 226 RKADLEK-----------ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 658 QLTQVRDSLSQGTKRLHQLQLDKATKSTQLNNAEAQAKQREAKRGQLAETVARTQAELAE 717 T + L+ +KA Q A + E + +AE + Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Query: 718 LAEQLMLLAEQEDELAEALEVSLEQQQQQSQDAQGDMARHQALKAQIGDAERRLASLNAS 777 L EQ + L L+ S E ++Q + Q +++ +A R L + + Sbjct: 335 LEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREA 394 Query: 778 LQSVTTRMAVSTEQIELQRVRVSELVHSKE 807 + V + + ++ EL SK+ Sbjct: 395 KKQVEKALEEANSKLAALEKLNKELEESKK 424
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.004 Identities = 28/136 (20%), Positives = 42/136 (30%), Gaps = 21/136 (15%) Query: 70 AVRVRKANEAHTPEAPAFNPYLKQEAKAQPQPVEPVQVEPKPLFKQEPSMAQPDFSLQSP 129 +V A EAP P ++ E + E K + K E Q Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNE----------QDA 1058 Query: 130 TAKEQHRGPKASRQEPVLPGHSANLAQAHVGQSHAAMVAQKAAEEQRAQVQMPTQTALFD 189 T A + + AN V AQ +E + Q +TA + Sbjct: 1059 TETTAQNREVAKEAKSNVK---ANTQTNEV--------AQSGSETKETQTTETKETATVE 1107 Query: 190 EEEAYEEEQPQVVEQP 205 +EE + E + E P Sbjct: 1108 KEEKAKVETEKTQEVP 1123 Score = 29.6 bits (66), Expect = 0.020 Identities = 25/140 (17%), Positives = 46/140 (32%), Gaps = 13/140 (9%) Query: 70 AVRVRKANEAHTPEAPAFNPYLKQEAKAQPQPVEPVQVEPKPLFKQEPSMAQPDFSLQSP 129 + A E T + K KA Q E Q E Q + ++ Sbjct: 1052 EKNEQDATET-TAQNREVAKEAKSNVKANTQTNEVAQS------GSETKETQTTETKETA 1104 Query: 130 TAKEQHRGPKASRQEPVLPGHSANLA----QAHVGQSHAAMVAQKAAEEQRAQVQMPTQT 185 T +++ + + + +P ++ ++ Q+ Q A + + Q T T Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 186 ALFDEEEAYEEEQPQVVEQP 205 + E +E VEQP Sbjct: 1165 T--ADTEQPAKETSSNVEQP 1182
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 31.5 bits (71), Expect = 0.009 Identities = 15/107 (14%), Positives = 37/107 (34%), Gaps = 7/107 (6%) Query: 504 MLDRMGIKSATNLALAIEAAKTTTLPRFLYALGIREVGETTAANLAT---HFGSLEALRV 560 M + ++ ++ A + + + + E+ + HF L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 561 ATIEQLIQVEDIGEVVAQHVAHFFAQPHNL--EVIDALIAAGVNWPA 605 E +IGE+ ++ A F P ++ E++ ++ + V Sbjct: 61 EIWEL--SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER 105
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.019 Identities = 9/21 (42%), Positives = 12/21 (57%) Query: 31 PIALVGPNGAGKTTLFSLLCG 51 + L G G GK+TL + L G Sbjct: 598 SVVLEGTGGIGKSTLINTLVG 618
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 26.7 bits (59), Expect = 0.048 Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 134 ELVKSHVGFYQDNAADYEQELISLLKE 160 ++ FY+ N +Y +L L KE Sbjct: 160 AKDPNNKEFYEKNLKEYTDKLDKLDKE 186
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.6 bits (61), Expect = 0.004 Identities = 15/52 (28%), Positives = 21/52 (40%), Gaps = 8/52 (15%) Query: 3 KIALIAVSLMIVGLTGCSSLGVQ------PWEKGQFARADMALDSEKLDQAL 48 K+ L A++L L GC+S G P E F R + LD + Sbjct: 2 KLRLSALALGTTLLVGCASSGTDQQGRSDPLEG--FNRTMYNFNFNVLDPYI 51
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 31.4 bits (71), Expect = 0.009 Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 1/90 (1%) Query: 88 DLKLVVDSLTGASASGAVAQSDSQTFTRPSGNGQYKVAAGETPLDDTFHDTRVQGSANWS 147 DL++ + G++ V S R G+ +Y + AGE + + + Sbjct: 343 DLQVTIKEADGSTQIFTVPYSSVPLLQRE-GHTRYSITAGEYRSGNAQQEKPRFFQSTLL 401 Query: 148 QALNSDWKVNGGVYGSKEFDYMSMGINAGL 177 L + W + GG + + + GI + Sbjct: 402 HGLPAGWTIYGGTQLADRYRAFNFGIGKNM 431
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 4e-22 Identities = 33/119 (27%), Positives = 58/119 (48%), Gaps = 1/119 (0%) Query: 2 RIMLVEDNELLAQGICLSLAKMGMQVDHLSSYQQALVGIKNETFSAIVLDLGLPDGNGKE 61 I++ +D+ + + +L++ G V S+ I +V D+ +PD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLKAWRAEGVSIPTIVLTANTDFDTKLECLDIGADDYLGKPFDVRELAARI-RAIVRRQ 119 LL + +P +V++A F T ++ + GA DYL KPFD+ EL I RA+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 65.7 bits (160), Expect = 9e-14 Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 7/146 (4%) Query: 24 QLLFMLVFMVACGQMAQTIFVPALPLIAQGLAVDASKLQAVMACYLLAYGLCQFIYGPLS 83 Q+L L + + + + +LP IA + V ++L + + +YG LS Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 84 DRVGRKMPLLIGIGIFILGALMAA-EATSFNQLIFASLLQGLGTA-----SAGALCRSIP 137 D++G K LL GI I G+++ + F+ LI A +QG G A + R IP Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 138 RDHYFGDNLVRFNSYVSMAVVFLPLV 163 +++ G S V+M P + Sbjct: 134 KENR-GKAFGLIGSIVAMGEGVGPAI 158
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 45.6 bits (108), Expect = 3e-07 Identities = 29/147 (19%), Positives = 63/147 (42%), Gaps = 10/147 (6%) Query: 111 VNRLKAKLSSQQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEV 170 +L ++ L++ E ++ K Y+ +QL + L L Q N+ E+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQL--VTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 171 EEAELELSYTEIKAPIAGLVSRSEV-DIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDY 229 + E + I+AP++ V + +V G +V + ++L+ V + D + V+ + D Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT-AETLMVIVPEDDTLEVTALVQNKDI 377 Query: 230 ------LNAQRRLTSYSAKKEAEVEGK 250 NA ++ ++ + + GK Sbjct: 378 GFINVGQNAIIKVEAFPYTRYGYLVGK 404 Score = 37.9 bits (88), Expect = 6e-05 Identities = 21/176 (11%), Positives = 60/176 (34%), Gaps = 14/176 (7%) Query: 73 EVRARVDGFVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSSQ-------QAIL 125 E++ + V+E EG +V+ G++L ++ A + ++ L Q + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 126 DKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEVEEAELELSYTEIKAP 185 E + L ++ + + L + + + + + + EL+ + +A Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK--YQKELNLDKKRAE 215 Query: 186 IAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYSA 241 +++R I + +R+ + ++ L + + Sbjct: 216 RLTVLAR----INRYENLS-RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 964 bits (2494), Expect = 0.0 Identities = 425/1028 (41%), Positives = 618/1028 (60%), Gaps = 9/1028 (0%) Query: 1 MAQFFINRPIFASVISIVIVLLGVIAMFKLPVDQYPYITPPQVTISASYPGASSTTAAES 60 MA FFI RPIFA V++I++++ G +A+ +LPV QYP I PP V++SA+YPGA + T ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VATPLEQEVNGVPNMIYMSSKSTNSGGTSVTITFDVGTNADLAAVDVQNSAQQASGGLPI 120 V +EQ +NG+ N++YMSS S ++G ++T+TF GT+ D+A V VQN Q A+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 DVQTEGVTVSKDASVELLKLALTSNDERFDEIYLSNYATINIESALRRIPGVGRTRNTGS 180 +VQ +G++V K +S L+ S++ + +S+Y N++ L R+ GVG + G+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 RSYAMRIWLKPDAMAGYSLTTTDVINAIKAQNKESPAGTIGTQPNNDDISLTLPISVAGR 240 + YAMRIWL D + Y LT DVIN +K QN + AG +G P L I R Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LSSVQAFNEIIVRANPDGSIIRLRDIAGVELGSSAYTLQSQLNGENATILQVYLLPGANA 300 + + F ++ +R N DGS++RL+D+A VELG Y + +++NG+ A L + L GANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LEVTRKVKQTMAELSQKFPQGMKWEVFYDASIFIQESIDEVIHTLIEALVLVVLVVYLFL 360 L+ + +K +AEL FPQGMK YD + F+Q SI EV+ TL EA++LV LV+YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNVRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIGIVVDDAIVVVENVERL 420 QN+RATLIP IAVPV L+GT A + AFG++INT+++ +VLAIG++VDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 IHEKGMSAIDATRIAMKELSGALVATSLVLCAVFVPVSFLAGITGIMYREFAVAITVAVL 480 + E + +AT +M ++ GALV ++VL AVF+P++F G TG +YR+F++ I A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 ISTLVALTLSPALCALLLKPSKAPE----RGFFHWLNRKLDVGTNQYVGLVALTNKYAKR 536 +S LVAL L+PALCA LLKP A GFF W N D N Y V R Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 537 SYLAFAIMFGGTYFIMSHLPSSFMPDEDQGRFFIDMTLPDGSTVNRTEAILKKAEQYVRA 596 L +A++ G + LPSSF+P+EDQG F + LP G+T RT+ +L + Y Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 597 NPAV-AYSFTLAGENRRSGANQANGQFEVVLKPWAEREASHATVQSVMKAIDKDLKNVLE 655 N S SG Q G V LKPW ER + ++V+ +L + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 656 AEFNLYLPSAVPGLGNGSGVEMQLQDTSGTHFDGLIETANELVEQLKLQP-EVASASVSL 714 + A+ LG +G + +L D +G D L + N+L+ P + S + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 715 QSAIPQLHLTVDEAKAMAIGVNVSDIYSTIKTLTDSSTVNDFNLFGRVYRVKIQAEESYR 774 Q L VD+ KA A+GV++SDI TI T + VNDF GRV ++ +QA+ +R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 775 QFPHQIKDYYVRSSSGAMVPIGVLAKYDYTVGPSSVTHYNLFSSASINVTPATGYATGDV 834 P + YVRS++G MVP + G + YN S I A G ++GD Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 835 IQAIERVATPILPDEFKYEWTGITYQEVQSANQTGIAIGLALLFVFLFLAALYESWSIPV 894 + +E +A+ LP Y+WTG++YQE S NQ + ++ + VFL LAALYESWSIPV Sbjct: 840 MALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 895 AVLLIAPIALLGAAVTTLISGMQSNLFFQVAFIALIGMAAKNAILIVEFANQLH-QQGRT 953 +V+L+ P+ ++G + + +++++F V + IG++AKNAILIVEFA L ++G+ Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 954 RISAALEAATMRFRPILMTSMAFILGVLPLVLSEGPGAVSRQSISLPILGGMVLATTIGI 1013 + A L A MR RPILMTS+AFILGVLPL +S G G+ ++ ++ + ++GGMV AT + I Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1014 VFVPLFFV 1021 FVP+FFV Sbjct: 1019 FFVPVFFV 1026 Score = 108 bits (272), Expect = 4e-26 Identities = 74/513 (14%), Positives = 183/513 (35%), Gaps = 37/513 (7%) Query: 5 FINRPIFASVISIVIVLLGVIAMFKLPVDQYPYITPPQVTISASYPGASSTTAAESVATP 64 + +I +IV V+ +LP P P ++ + V Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 65 LEQ-----EVNGVPNMIYMSSKSTNSGGTSVTITF------DVGTNADLAAVDVQNSAQQ 113 + E V ++ ++ S + + + F + + +A V + A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 114 ASGGLP--------IDVQTEGVTVSKDASVELLKLALTSNDERFDEIYLSNYATINIESA 165 G + + E T + EL+ A +D L+ + A Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATG-FDFELIDQAGLGHDA------LTQARNQLLGMA 705 Query: 166 LRRIPGVGRTRNTGS-RSYAMRIWLKPDAMAGYSLTTTDVINAIKAQNKESPAGTIGTQP 224 + + R G + ++ + + ++ +D+ I + + Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 225 NNDDISLTLPISVAGRLSSVQAFNEIIVRANPDGSIIRLRDIAGVELGSSAYTLQSQLNG 284 + + A + +++ VR + +G ++ + L + NG Sbjct: 766 RVKKLYVQAD---AKFRMLPEDVDKLYVR-SANGEMVPFSAFTTSHWVYGSPRL-ERYNG 820 Query: 285 ENATILQVYLLPGANALEVTRKVKQTMAELSQKFPQGMKWEVFYDASIFIQESIDEVIHT 344 + +Q PG ++ + ++ ++L P G+ + S + S ++ Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASKL----PAGI-GYDWTGMSYQERLSGNQAPAL 875 Query: 345 LIEALVLVVLVVYLFLQNVRATLIPAIAVPVSLIGTLAAMLAFGFTINTVSLLALVLAIG 404 + + V+V L + ++ + + VP+ ++G L A F + ++ L+ IG Sbjct: 876 VAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIG 935 Query: 405 IVVDDAIVVVENVERLIHEKGMSAIDATRIAMKELSGALVATSLVLCAVFVPVSFLAGIT 464 + +AI++VE + L+ ++G ++AT +A++ ++ TSL +P++ G Sbjct: 936 LSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAG 995 Query: 465 GIMYREFAVAITVAVLISTLVALTLSPALCALL 497 + + ++ +TL+A+ P ++ Sbjct: 996 SGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 74.1 bits (182), Expect = 2e-15 Identities = 79/501 (15%), Positives = 172/501 (34%), Gaps = 37/501 (7%) Query: 539 LAFAIMFGGTYFIMSHLPSSFMPDEDQGRFFIDMTLPDGSTVNRTEAILKKAEQYVRANP 598 LA +M G I+ LP + P + P + + + EQ + Sbjct: 15 LAIILMMAGALAILQ-LPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGID 73 Query: 599 AVAYSFTLAGENRRSGANQANGQFEVVLKP-WAEREASHATVQSVMKAIDKDLKNVLEAE 657 + Y ++ + +G+ F+ P A+ + +Q + ++++ Sbjct: 74 NLMY---MSSTSDSAGSVTITLTFQSGTDPDIAQVQVQ-NKLQLATPLLPQEVQ------ 123 Query: 658 FNLYLPSAVPGLGNGSGVEMQLQDTSGTHFDGLIETANELVEQLKLQPEVAS--ASVSLQ 715 + + S M S + ++ + +K + V L Sbjct: 124 -----QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 716 SAIPQLHLTVDEAKAMAIGVNVSDIYSTIKTLTDSSTVNDFNLFGRVYRVKIQA---EES 772 A + + +D + D+ + +K D + ++ A ++ Sbjct: 179 GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 773 YRQFPHQIKDYYVRSS-SGAMVPIGVLAK-YDYTVGPSSVTHYNLFSSASINVTPATGYA 830 + P + +R + G++V + +A+ + + N +A + + ATG Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 831 TGDVIQAI-ERVAT--PILPDEFKYEWTGITYQEVQSANQT-----GIAIGLALLFVFLF 882 D +AI ++A P P K + T VQ + AI L L ++LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 883 LAALYESWSIPVAVLLIAPIALLGAAVTTLISGMQSNLFFQVAFIALIGMAAKNAILIVE 942 L ++ + + P+ LLG G N + IG+ +AI++VE Sbjct: 359 L----QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 943 FANQLHQQGRTRISAALEAATMRFR-PILMTSMAFILGVLPLVLSEGPGAVSRQSISLPI 1001 ++ + + A E + + + ++ +M +P+ G + S+ I Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 1002 LGGMVLATTIGIVFVPLFFVT 1022 + M L+ + ++ P T Sbjct: 475 VSAMALSVLVALILTPALCAT 495
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 32.3 bits (73), Expect = 0.003 Identities = 14/55 (25%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 246 SEPFAAYNAVKDWLNESKITEGHLFRSISRDGKTLRPYQISDNVT-SKSSLIRNS 299 ++ YN V +N +K+ G + + +GK Y +DN+ +K +L N+ Sbjct: 331 TDKVTRYNTVTVAMNTTKLANGISYYEVIENGKATGKYINADNIDGTKRTLKHNA 385
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 7e-05 Identities = 15/70 (21%), Positives = 32/70 (45%), Gaps = 10/70 (14%) Query: 420 EIDKGMIEKLVDPLT--HLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAV 477 +I+ +++ V P+ LV N + HGI + + G + LK ++ G++ + V Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEV 296 Query: 478 HDDGGGLNRE 487 + G + Sbjct: 297 ENTGSLALKN 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 1e-22 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%) Query: 1 MSK-KILIVDDSAAIRQMVEATLKSANYQVVLAKDGREALDLCGGQRFDFILTDQNMPRM 59 M+ IL+ DD AAIR ++ L A Y V + + D ++TD MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGLTLIKSLRGMSAFIRTPIVMLTTEAGEDMKAQGRAAGATGWMVKPFDPQKLLAITAKV 119 + L+ ++ A P+++++ + + GA ++ KPFD +L+ I + Sbjct: 61 NAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LG 121 L Sbjct: 119 LA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.7 bits (168), Expect = 2e-14 Identities = 28/104 (26%), Positives = 50/104 (48%) Query: 8 ILVIEDDLVTNQIITAFIHSKGWGVITCCSLEEASEEIYQQNIELILLDYFLPDGSALTL 67 ILV +DD ++ + G+ V + I + +L++ D +PD +A L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LEKLRYCESPVPVIVISADNEYQKILSCFRLGALDYIIKPINLE 111 L +++ +PV+V+SA N + + GA DY+ KP +L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.8 bits (67), Expect = 0.018 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 5/57 (8%) Query: 11 FAAVIGYFIGS---LVSFTLSTLVAVIIMLGWQFYRQSSASQPIPHSFATSAASGDW 64 A +G ++G + LS+LV + +G R S+PIP F A W Sbjct: 218 LLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNHHQSKPIP--FGPYLAIAGW 272
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 134 bits (338), Expect = 3e-36 Identities = 83/390 (21%), Positives = 172/390 (44%), Gaps = 15/390 (3%) Query: 50 LDTTIANVALPHMQGSMGATQDQISWVLTSYIVAAAIFMPLTGFLTARIGRKRVFMWAVV 109 L+ + NV+LP + +WV T++++ +I + G L+ ++G KR+ ++ ++ Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 110 GFTIASMLCGAAQNLEQIVLF-RLLQGVFGASLVPLSQSVLLDSYPPERHGSAMALWGVG 168 S++ + +++ R +QG A+ L V+ P E G A L G Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 169 VMVGPILGPSLGGWLTEYYNWRWVFYINLPFGLLAWFGLAAYVKETPLDHSRKFDLLGFA 228 V +G +GP++GG + Y +W + + +P + + + + FD+ G Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGII 205 Query: 229 MLSLAIGALQMLLDRGESLDWFSSREIVIEAIIAGMAFYLFIAHIFTHKHPFIEPGLFKD 288 ++S+ I + F++ + I++ ++F +F+ HI PF++PGL K+ Sbjct: 206 LMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKN 255 Query: 289 RNFSVGLIFIFIIGIILLATMALLPPFMQTLLGYPVIDVGY-LLAPRGVGTMIAMMTVGK 347 F +G++ II + ++++P M+ + ++G ++ P + +I G Sbjct: 256 IPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI 315 Query: 348 LAGKVDVRYQIFLGLMLTILSLWEMTGFNTNITGWDIVRTGVIQGLGLGFIFVPLSTITF 407 L + Y + +G+ +S F T W + V GL F +STI Sbjct: 316 LVDRRGPLYVLNIGVTFLSVSFLTA-SFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVS 374 Query: 408 ATLAAKYRNEGTALFSLMRNIGSSIGISVV 437 ++L + G +L + + GI++V Sbjct: 375 SSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 85.7 bits (212), Expect = 1e-20 Identities = 41/263 (15%), Positives = 83/263 (31%), Gaps = 29/263 (11%) Query: 99 AKLAQVKTDLAVLKASYHEKQAEITLAETKLAFAEKEQKRQENLIGKHFVS-------ES 151 + Q + +L +A A I E + +L+ K ++ E+ Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 152 QLEDARQNTDIARQNIQTLQKDLHRIAESLGGSP-DFPIEQHPSYLEALAQLNE------ 204 + +A + + ++ ++ ++ E F E + + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319 Query: 205 -AKLDLSRVEIKAPVSGVVSQLP--KLGQYVNVGAIALALV-ADHALWIEANFTETDLTH 260 + I+APVS V QL G V + +V D L + A D+ Sbjct: 320 KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGF 379 Query: 261 VKPGQKVNIHIDTFPDN---HWQGTVESLSPATGAEFSLIPAQNATGNWVKIAQRVPVRI 317 + GQ I ++ FP + G V++++ G + + Sbjct: 380 INVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEENC 432 Query: 318 AIDTALPEAPLRAGLSAVVDIDT 340 PL +G++ +I T Sbjct: 433 LST-GNKNIPLSSGMAVTAEIKT 454 Score = 54.4 bits (131), Expect = 3e-10 Identities = 22/138 (15%), Positives = 43/138 (31%), Gaps = 12/138 (8%) Query: 50 VKADKVPVSAQVAGNVDSLYVVENQRVEKGKVLFRLDDAMFKVMVDKASAKLAQVKTDLA 109 + V + V E + V KG VL +L + K + L Q + + Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151 Query: 110 VLKASY----HEKQAEITLAETK--LAFAEKEQKRQENLIGKHFVSESQLEDARQNTDIA 163 + K E+ L + +E+E R +LI + Q + Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI------KEQFSTWQNQKYQK 205 Query: 164 RQNIQTLQKDLHRIAESL 181 N+ + + + + Sbjct: 206 ELNLDKKRAERLTVLARI 223
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.5 bits (66), Expect = 0.025 Identities = 11/39 (28%), Positives = 16/39 (41%) Query: 95 LINSLISKITQLNQGTEAFSSTLADFGLQLQTKPDVCTL 133 LIN L+ + LN +FS L G L + + Sbjct: 187 LINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKHLNGV 225
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 71.5 bits (175), Expect = 1e-16 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 2/92 (2%) Query: 142 ELALGMNVQFRTGSSELESHFLPQLDNVAKVMKRSSESN--LELKGYADRRGDLAYNQAL 199 L +V F + L+ LD + + + + + GY DR G AYNQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 200 SEQRLLEVRGYLIKQGVAPERITTQAFGARMP 231 SE+R V YLI +G+ ++I+ + G P Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNP 305
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 4e-14 Identities = 29/134 (21%), Positives = 54/134 (40%), Gaps = 5/134 (3%) Query: 3 RIAIVEDEAAIRENYKDVLQQHGYSVQTYADRPSAMLAFNTRLPDLAIIDIGLGNEIDGG 62 I + +D+AAIR L + GY V+ ++ + DL + D+ + +E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NA 62 Query: 63 FMLCQSLRAMSSTLPIIFLTARDSDFDTVCGLRLGADDYLSKEVSFPH---LTARLAALF 119 F L ++ LP++ ++A+++ + GA DYL K + R A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 120 RRSELATSQTPQEN 133 +R Q+ Sbjct: 123 KRRPSKLEDDSQDG 136
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 42.4 bits (100), Expect = 3e-06 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Query: 191 AAKRAGFVDVAFLFEPLAAGMDYEASLSADQTVLVVDVGGGTTDCSVVKMGPKHQASFDR 250 +A+ AG +V + EP+AA + +S +VVD+GGGTT+ +V+ + Sbjct: 129 SAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN--------- 179 Query: 251 SADCLGHSGQRIGGNDLDIAL 271 + S RIGG+ D A+ Sbjct: 180 --GVVYSSSVRIGGDRFDEAI 198
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.7 bits (72), Expect = 0.007 Identities = 17/36 (47%), Positives = 24/36 (66%) Query: 137 NIVIDIGGGSTEVVLGQKNTPTYLSSLRCGCVSFNE 172 ++V+DIGGG+TEV + N Y SS+R G F+E Sbjct: 161 SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDE 196
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.010 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGRSLLARAI 53 + GESG+G+ L+ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.2 bits (60), Expect = 0.024 Identities = 22/106 (20%), Positives = 36/106 (33%), Gaps = 14/106 (13%) Query: 51 LEGEMVGCAAIKAGSGPVGELGYLVVSPLYRRRGIAQGLTLKRIEVAKAQGIALLFATIR 110 LE +G I++ + + V+ YR++G+ L K IE AK L + Sbjct: 72 LENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131 Query: 111 DENNASRVNLLKAGFHFWRNYLSIRGTGNTVGWYYLALQESVDIDG 156 D N S HF+ + +G L + Sbjct: 132 D-INISAC-------HFYAKH------HFIIGAVDTMLYSNFPTAN 163
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 20/106 (18%), Positives = 34/106 (32%), Gaps = 26/106 (24%) Query: 327 LISNAIRY----TEPGGKITVQWRSVATGGLFSVTDTGEGIAPQHISRLTERFYRVDSAR 382 L+ N I++ GGKI ++ V +TG Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 383 SRQTGGSGLGLAIVKHALSHHHSE---LNISSELGKGSTFSFVIPS 425 +G GL V+ L + + +S + GK + +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 2e-23 Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 4/130 (3%) Query: 3 ARILIVEDELAIREMLTFVMEQHGFTTSAAEDFDSAIALLKEPYPDLILLDWMFPGGSGI 62 A IL+ +D+ AIR +L + + G+ + + + DL++ D + P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QLAKRLKQDEFTRQIPIIMLTARGEEEDKVKGLEVGADDYITKPFSPKELVARIKAVL-- 120 L R+K+ +P+++++A+ +K E GA DY+ KPF EL+ I L Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 RRSAPTRLEE 130 + P++LE+ Sbjct: 122 PKRRPSKLED 131
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 81.0 bits (200), Expect = 1e-19 Identities = 79/335 (23%), Positives = 126/335 (37%), Gaps = 33/335 (9%) Query: 7 KTLLASALASATLASAYAAEPLTVYGKLNV---TAQSNDEKGDST------TTIQSNASR 57 K+L+A LA+ +A A +T+YG + T++S G T I S+ Sbjct: 3 KSLIALTLAALPVA---AMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSK 59 Query: 58 FGVKGDFELSSSLEAFYTVEYEVDTGAATSDNFKARNQFVGLKGAFGSFSVGRNDTLLKI 117 G KG +L + L+A + VE + A T + R F+GLKG FG VGR +++LK Sbjct: 60 IGFKGQEDLGNGLKAIWQVEQKASI-AGTDSGWGNRQSFIGLKGGFGKLRVGRLNSVLK- 117 Query: 118 SQGNVDQFNDLSGDL--KSLFKGENRLGQTATYLSPSIGGFVFGATYAAEGDADQQAQDG 175 G+++ ++ S L + + E RL + Y SP G YA +A + + Sbjct: 118 DTGDINPWDSKSDYLGVNKIAEPEARL-ISVRYDSPEFAGLSGSVQYALNDNAGRHNSES 176 Query: 176 FSLAAMYGDAKLKKSPFYAAIAYDSDVKGYEILRASVQGKI----ADLTLGGMYQQQEQT 231 + Y + A + + I + + + D + QQ+ Sbjct: 177 YHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQDA 236 Query: 232 YKNSLPVNTDSVNGYLLSAAYDINAVTLKAQY----------QDMEDLGDSWSVGADYSL 281 + +S + AY VT + Y + + D VGA+Y Sbjct: 237 KLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYDF 296 Query: 282 GKPTKVFAFYT--NRSMEASNDDDKYIGVGLEHKF 314 K T S GVGL HKF Sbjct: 297 SKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.006 Identities = 10/41 (24%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 81 ESLEEKVAQIEDEENRKLAKKEKDALKD-EIITSLLPRAFS 120 ++E ++ ++ DEE + + + L+ E++ +L+P AF+ Sbjct: 29 NAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFA 69
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.0 bits (132), Expect = 1e-11 Identities = 21/134 (15%), Positives = 44/134 (32%), Gaps = 4/134 (2%) Query: 13 DKRQQLISTAFKLFYFQSVHGVGINQILQESAIAKKTLYHHFASKDELVEAVVLYRDRVF 72 + RQ ++ A +LF Q V + +I + + + + +Y HF K +L + + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 73 YQWLSERVLAV-EMGTAGIRVLFMALDDWFNQRVPQLCEFRGCFFINVSAEFTDASHPVH 131 + E + +R + + + + + F EF V Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTE-ERRRLLMEIIF--HKCEFVGEMAVVQ 127 Query: 132 RLCAEHKQRVADLI 145 + D I Sbjct: 128 QAQRNLCLESYDRI 141
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 137 bits (345), Expect = 3e-43 Identities = 65/132 (49%), Positives = 88/132 (66%), Gaps = 2/132 (1%) Query: 25 KAAQENIRLGNEFLAQNKNQEGVKTTASGLQYQVLQQGTGTVHPKASDTVTVHYHGTLID 84 K A+EN G+ FL+ NK++ G+ SGLQY+++ GTG P SDTVTV Y GTLID Sbjct: 99 KKAEENKAKGDAFLSANKSKPGIVVLPSGLQYKIIDAGTGA-KPGKSDTVTVEYTGTLID 157 Query: 85 GTVFDSSVERGEPIAFPLNRVIKGWTEGVQLMVEGDKYRFFIPSELAYGNRST-GKIGGG 143 GTVFDS+ + G+P F +++VI GWTE +QLM G + F+P++LAYG RS G IG Sbjct: 158 GTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPN 217 Query: 144 SVLIFDVELLKI 155 LIF + L+ + Sbjct: 218 ETLIFKIHLISV 229
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 46.2 bits (109), Expect = 5e-07 Identities = 33/170 (19%), Positives = 65/170 (38%), Gaps = 15/170 (8%) Query: 542 WEIDADNGDILNAMHEGLGHGEGTMPPANKAPIANAGADITVTGTADVTLNGSASRDPEN 601 ++D + + + + G+ T NK P A +D +V ++ +G+ S+D + Sbjct: 744 HKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDG 803 Query: 602 GALSYQWSQVSGPSLSISNADMANAVVQLSEAASDVVYVFSLQVTDPEGLSSTDTVTLTH 661 +Y+W G ++ A A + ++ Y L VTD G +T++ + Sbjct: 804 EIKAYEWDFGDG-----EKSNEAKATHKYNKTGE---YEVKLTVTDNNGGINTESKKI-- 853 Query: 662 KAETANQAPVV--TVPASVTVEAGQSVSINATAT---DADGDSLTYAWTV 706 K V+ + P + +A Q N + S Y + V Sbjct: 854 KVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDV 903
>FLAGELLIN#Flagellin signature. Length = 507 Score = 31.6 bits (71), Expect = 0.008 Identities = 14/87 (16%), Positives = 33/87 (37%), Gaps = 4/87 (4%) Query: 282 QLASAMEEMSSTIAEVAQNTQLTSTSINTAYDLCLKSSANMKANTQKVEQLAKSVADAAN 341 +A+ + + ++N + T + + N Q+V +L+ + N Sbjct: 48 AIANRFTSNIKGLTQASRNANDGISIAQTTE----GALNEINNNLQRVRELSVQATNGTN 103 Query: 342 NAHQLNKEAERVASAMGEIDSIAEQTN 368 + L + + + EID ++ QT Sbjct: 104 SDSDLKSIQDEIQQRLEEIDRVSNQTQ 130
>SECA#SecA protein signature. Length = 901 Score = 32.5 bits (74), Expect = 0.004 Identities = 37/175 (21%), Positives = 67/175 (38%), Gaps = 46/175 (26%) Query: 220 SQVVYPVEQRRKRELLSELIGK-KNWQQVLVFTATRDAADTLVKELNLDGIPSEVVHGEK 278 +VY E + + ++ ++ + Q VLV T + + ++ + EL GI V++ Sbjct: 424 PDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLN--- 480 Query: 279 AQGSRRRALREFVSGKVR---VLVATEVAARGLDI---------------PSLEYVVNFD 320 A+ A V+ V +AT +A RG DI P+ E + Sbjct: 481 AKFHANEA--AIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIK 538 Query: 321 LPFLAED---------YV-----H---RI-----GRTGRAGKSGVAISFVSREEE 353 + ++ H RI GR+GR G +G + ++S E+ Sbjct: 539 ADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDA 593
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.7 bits (129), Expect = 6e-10 Identities = 46/320 (14%), Positives = 95/320 (29%), Gaps = 80/320 (25%) Query: 66 ITPAVKGLVISVEAKPNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQLAAAWE 125 I P +V + K +++GDVL ++ EA + +++LL A E + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 126 AAKANV---------ARVAADRERNKSAY--------------------DRYEQGHRKGG 156 + + N E + ++ + Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 157 ANSPFTALE---------LDNRRQLF---FASEAQLTAAQAE--ELRARLA-YESNVDGV 201 + E LD+ L ++ + + + E L Y+S ++ + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 202 NSKVAGLQGDL-----------------------------ESALYNLEQTVVRAPADGIV 232 S++ + + + +V+RAP V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 233 TQMALR-PGAMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLL-RLQEGDEAEVVLDAAPGQ 290 Q+ + G V +M +P++ A QN + + G A + ++A P Sbjct: 339 QQLKVHTEG--GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 291 ---VFKGKVAKVLPAMAEGE 307 GKV + E + Sbjct: 397 RYGYLVGKVKNINLDAIEDQ 416
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.039 Identities = 55/293 (18%), Positives = 102/293 (34%), Gaps = 66/293 (22%) Query: 272 RAPATQATTDDKATVQP-DAPKGVLLLGVQGSGKSLAAKAV---AGVWQRPLLRLDMGAL 327 R+ A Q A + D +++ G G+GK L A+A+ P + ++M A+ Sbjct: 142 RSAAMQEIYRVLARLMQTDLT--LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI 199 Query: 328 YNKYIGETE-------------KNLRNALELADMMSPCILWIDEIEKGLSGSSS------ 368 I E+E E A+ + L++DEI + + Sbjct: 200 PRDLI-ESELFGHEKGAFTGAQTRSTGRFEQAEGGT---LFLDEIGD-MPMDAQTRLLRV 254 Query: 369 -DEGTSTRILGTLLTWMAERKSEVFVVATANDIQVLPPELMRKGRMDE-------IFFVD 420 +G T + G +S+V +VA N + + +G E + + Sbjct: 255 LQQGEYTTVGGR-----TPIRSDVRIVAATN---KDLKQSINQGLFREDLYYRLNVVPLR 306 Query: 421 LPDEAIRQAI---------FLIHCQRRGIDVTRLD---LAQLSRHSQGFSG--AEIEQAV 466 LP +R F+ ++ G+DV R D L + H + G E+E V Sbjct: 307 LP--PLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHP--WPGNVRELENLV 362 Query: 467 --IAAMYSARSLARSLDQDMLLEELTKTKPLSIVMGDKINALRQWAAGRTVNA 517 + A+Y + R + ++ L E+ + ++ Q Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQY 415
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 31.3 bits (71), Expect = 0.005 Identities = 10/28 (35%), Positives = 13/28 (46%), Gaps = 2/28 (7%) Query: 17 GCGELGKEVAIELQRLGVEVIGVD--RY 42 G L K V LQ+ G V+G +Y Sbjct: 62 GWATLDKAVGGILQQQGWPVVGWSSLKY 89
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 31.9 bits (72), Expect = 0.006 Identities = 23/112 (20%), Positives = 40/112 (35%), Gaps = 20/112 (17%) Query: 372 GMIWFRLPLEGDKRVWPLSTLIAVAQQQPLAPHIELEIL--------NQANTEPAQHEAP 423 MI++R+ L + V + A A+QQP+ + + + A P Sbjct: 31 AMIFWRIGLPDNAPVSSVQITPAQARQQPVTLN-DFTLFGVSPEKNKAGALDASQMSNLP 89 Query: 424 KTSLFQLVLVNKGNLAGELPGQLSLAAQACSGY-------DAQNGYQAKLTQ 468 + L L G +AG+ S+A + + GY AK+ Sbjct: 90 PS---TLNLSLTGVMAGDDD-SRSIAIISKDNEQFSRGVNEEVPGYNAKIVS 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 6e-19 Identities = 31/169 (18%), Positives = 60/169 (35%), Gaps = 23/169 (13%) Query: 10 TLLLVDDEPVNLRVLKQVLHQ-DYHLIFAKSGEEALRLAQTELPSLILLDIMMPNMTGLE 68 T+L+ DD+ VL Q L + Y + + R L++ D++MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 VCQLLKNISETQSIPVIFVTALNDEHDEAAGFAVGGVDYIVKPISATIVKARVKTHLSLV 128 + +K +PV+ ++A N G DY+ KP T + + L+ Sbjct: 65 LLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 129 QADELRRTR---------------LQVIQRLGRAAEYKDN-----ETGT 157 + + ++ + L R + E+GT Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGT 171
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 2e-12 Identities = 27/122 (22%), Positives = 46/122 (37%), Gaps = 5/122 (4%) Query: 789 TLLVVDDIQQNIDLLSVWLTRQGHKVITARDGEQALLRMQKADIDITLMDLQMPVMDGLT 848 T+LV DD +L+ L+R G+ V + + D D+ + D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 849 AAKMRREQEAESQLPHMPIIALTASVLEQDKSAAEQAGMDGFANKPIDFALLTREIARVL 908 + P +P++ ++A A + G + KP D L I R L Sbjct: 65 L-----LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 909 QL 910 Sbjct: 120 AE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 4e-06 Identities = 24/121 (19%), Positives = 47/121 (38%), Gaps = 7/121 (5%) Query: 106 DYEADLMQAEATLAQATAALNEEIARGEVAKIEFKGYDKGLPPELGLRIPQLKKEQANVK 165 + E ++A L + L + + AK E++ + E+ + +L++ N+ Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI---LDKLRQTTDNIG 312 Query: 166 YAQAALARAQRNLERTVIRAPFDGIIKARNV-DLGQYVTLGTNLGELY---DTSIAEIRL 221 LA+ + + +VIRAP ++ V G VT L + DT + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 222 P 222 Sbjct: 373 Q 373 Score = 37.9 bits (88), Expect = 6e-05 Identities = 25/125 (20%), Positives = 53/125 (42%), Gaps = 11/125 (8%) Query: 62 GVVTPKYKTQLVTEVQGRMLSISPQFVA-GGIVKKGDQLAQIEPSDYEADLMQAEATLAQ 120 G +T +++ + ++ + + V G V+KGD L ++ EAD ++ +++L Q Sbjct: 88 GKLTHSGRSKEIKPIENSI--VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145 Query: 121 ATA------ALNEEIARGEVAKIEFKGYD--KGLPPELGLRIPQLKKEQANVKYAQAALA 172 A L+ I ++ +++ + + E LR+ L KEQ + Q Sbjct: 146 ARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Query: 173 RAQRN 177 + Sbjct: 206 ELNLD 210
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 498 bits (1283), Expect = e-161 Identities = 213/1043 (20%), Positives = 448/1043 (42%), Gaps = 49/1043 (4%) Query: 11 FARNSVAANLLMWALLIGGLFSTVLINKEVFPSFNLNLLSITVAYPGAAPQEIEEGINIK 70 F R + A +L L++ G + + + +P+ +S++ YPGA Q +++ + Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 71 IEEAIQDINGIKKVTSVA-SEGVGAITVEVEDDYDVQTVLDEAKLRLDAI-STFPVNIEK 128 IE+ + I+ + ++S + S G IT+ + D + + +L P +++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 129 PQIFKIEPENNVIWV----SVYGDMSLHDMKELAKS-VRDDLTQLPSVTRAKVTGVRDYE 183 I + ++ + V S + D+ + S V+D L++L V ++ G Y Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQYA 183 Query: 184 IGIEVSEDKLREYGLTFSQVALAVQNSSIDLPGGSIRAEDG------DILLRTKGQAYTG 237 + I + D L +Y LT V ++ + + G + + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 238 DDFANIVVTTRTDGSRVMLPQVATIKDDFEERLEYTRFNGKPAAIIEVTSVNDQNALDIA 297 ++F + + +DGS V L VA ++ E R NGKPAA + + NALD A Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 298 QQVKDYVEKRRATLPANAQLDTWGDLTHYLKGRLNMMMSNMFYGALLVFVILALFL-DLK 356 + +K + + + P ++ D T +++ ++ ++ +F +LVF+++ LFL +++ Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 357 LAFWVMMGLPVCFLGTMLIMPLEPFSMTINMLTLFAFILVLGIVVDDAIVIGESAYSE-V 415 + +PV LGT I+ F +IN LT+F +L +G++VDDAIV+ E+ + Sbjct: 364 ATLIPTIAVPVVLLGTFAILAA--FGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 416 ERHGHSIDNVIRGAQKVAMPATFGVLTTIAAFIPMLMVSGPMGIIWKSIGMVVIMCLAFS 475 E + + ++ + A FIPM G G I++ + ++ +A S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 476 LVESKFILPAHLAHM-KFRKPGE---PTGFFGRFKDRFNNHVQHFIHHSYRNFLERCIQH 531 ++ + + PA A + K GFFG F F++ V H+ +S L Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYT-NSVGKILGSTG-- 538 Query: 532 RYNVVAAFIGVLILSIALVASGKVRWVFFPDIPSDFIQVQLEMDEGSSEQNTLKVVQDIE 591 RY ++ A I ++ + L ++ F P+ +++ G++++ T KV+ + Sbjct: 539 RYLLIYALIVAGMVVLFL----RLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVT 594 Query: 592 EALYKMNAKMEKDNGSEVVKHSFINMSSRTSAFIFAELTKGEDRDVDGET---IAAAWRE 648 + K + + V SF ++ + F L E+R+ D + + + Sbjct: 595 DYYLKNEKANVESVFT-VNGFSFSGQ-AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 649 QLPELLSVKKLDFNAS-----GNGGGGGDISFRLTSSDLEELSAAARELKQKLATY-EGV 702 +L ++ + FN G G + L+ A +L A + + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 703 YDIADNFSSGSHEIRLKI-RPEAEALGLTLSDLARQVRYGFYGYEAQRILRNKEEIKVMV 761 + N + + +L++ + +A+ALG++LSD+ + + G + K+ V Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 762 RYPLEQRRTVGYLENMLIRTPQGKSVPFSTVAEVEKGESYASITRVDGKRAITIIANANK 821 + + R ++ + +R+ G+ VPFS + R +G ++ I Sbjct: 773 QADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE--- 829 Query: 822 HKVEPSKVVNEIQQDFLPQLQAKYPK-IQTTLDGGSLDEQNAMVGLMQGFFFALFTIYAL 880 P + + L +K P I G S E+ + + ++ Sbjct: 830 --AAPGTSSGDA-MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLC 886 Query: 881 MAVPLKSYSQPLIIMSVIPFGIIGALFGHLIQGLAMSVLSLCGIVALAGVVVNDSLILVD 940 +A +S+S P+ +M V+P GI+G L + V + G++ G+ +++++V+ Sbjct: 887 LAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE 946 Query: 941 FVNRARE-QGQSVRQAAVDSGCYRFRAIILTSLTTFVGLVPIILERSLQAQIVIPMATSL 999 F E +G+ V +A + + R R I++TSL +G++P+ + + + + Sbjct: 947 FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGV 1006 Query: 1000 AFGILFSTVVTLILVPLLYIILD 1022 G++ +T++ + VP+ ++++ Sbjct: 1007 MGGMVSATLLAIFFVPVFFVVIR 1029
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (294), Expect = 1e-33 Identities = 74/258 (28%), Positives = 120/258 (46%), Gaps = 6/258 (2%) Query: 34 LKGKVGLITGSTSGIGLATAHVLAEQGCHLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93 ++GK+ ITG+ GIG A A LA QG H+ PE + +++ AE H + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--P 63 Query: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153 AD+RD +I + +G IDILVN AG+ + ++W ++N + F+ Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 154 IQQAVPAMAEKRWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVAIECAEQGITVN 213 + M ++R G I+ + S V + AAY ++K V TK + +E AE I N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 214 AICPGWVDTPLINK-QIEAIASNKGLSYDEAKYQLVTAKQPLPEMLDPRQIGEFVLFLCS 272 + PG +T + + + + + ++ PL ++ P I + VLFL S Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGI---PLKKLAKPSDIADAVLFLVS 240 Query: 273 SAARGITGASLAMDGAWT 290 A IT +L +DG T Sbjct: 241 GQAGHITMHNLCVDGGAT 258
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 31.3 bits (71), Expect = 0.007 Identities = 22/114 (19%), Positives = 45/114 (39%), Gaps = 14/114 (12%) Query: 169 MALAAIINLILDPLLIFGIGPFPRLEIQGAAIATLFSWLIALSLSGYLLIIKRNMLEWAA 228 AL A++ L+ D LL G+ +L+ +A L + + S++ +++ Sbjct: 178 FALGAVVALVHDVLLTVGLFAVLQLKFDLTTVAALLT-ITGYSINDTVVV---------- 226 Query: 229 FDIDRMRANWSKLAHIAQPAALMNLINP-LANAVIMAMLAHIDHSAVAAFGAGT 281 DR+R N K + + +N L+ V+ M + + +G Sbjct: 227 --FDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDV 278
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 1e-06 Identities = 43/274 (15%), Positives = 91/274 (33%), Gaps = 49/274 (17%) Query: 25 SSVQASAIRPVKLFEVMQLEGGDFRTFPAR--VSANSRAELSFRISGELTDLALVEGQ-- 80 +V A R L V + DF + + ++ ++ E + + +L + + Q Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 81 QIRQGSLLAKLDDRDAYNNLMTREAEHELLAADFQRKTELLKRKLISQAEFDSAQAQLKS 140 QI L AK E++L+ F+ + + + Sbjct: 277 QIESEILSAKE--------------EYQLVTQLFKNEI---------LDKLRQTTDNIGL 313 Query: 141 AKAALAAARDQLSYTKLIAPFSGTVAKRLVDNH-QIVQANQGILTL-QNNSLLDVSIQVP 198 LA ++ + + AP S V + V +V + ++ + + L+V+ V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQ 373 Query: 199 EAMAASLNNYIQQQNFTAKVRFSALAGMEF---DAKFKEYSTQVTPGTQ---AYEVVFSL 252 + A ++ A + K K + + + V+ S+ Sbjct: 374 NKDIGFI-----NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISI 428 Query: 253 PQP------KDIQLLPGMSAELTLALVKTPDQTA 280 + K+I L GM+ A +KT ++ Sbjct: 429 EENCLSTGNKNIPLSSGMAVT---AEIKTGMRSV 459 Score = 28.6 bits (64), Expect = 0.036 Identities = 11/84 (13%), Positives = 30/84 (35%), Gaps = 5/84 (5%) Query: 68 SGELTDLALVEGQQIRQGSLLAKLDDRDAYNNLMTREAEHELLAADFQRKTELLKRKLIS 127 + + ++ + EG+ +R+G +L KL A + + ++ + R + L Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR-----YQILSR 158 Query: 128 QAEFDSAQAQLKSAKAALAAARDQ 151 E + + ++ Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEE 182
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 492 bits (1267), Expect = e-159 Identities = 207/1046 (19%), Positives = 441/1046 (42%), Gaps = 54/1046 (5%) Query: 3 IAEYSIRHKVISWMFVLLLLVGGGVSFTGLGQLEFPEFTIKEALVITAYPGASPEQVEEE 62 +A + IR + +W+ ++L++ G ++ L ++P V YPGA + V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTLPLEDALQQLDAVKHVTSI-NSAGLSQIQIEIKETYDKTSLPQVWDEVRRKVNDTAGQ 121 VT +E + +D + +++S +SAG I + + T +V+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQ---SGTDPDIAQVQVQNKLQLATPL 117 Query: 122 LPPGTSTPKVYDDFGD---VYGILFNLSGPDYSNRELSNYAD-YLRRELVLVPGVKKVSV 177 LP + + + F P + ++S+Y ++ L + GV V + Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 178 AGSVTEQVVIEISQQKLSALGLDQSYIYGLINNQNVVSNAGSLVVGDN------RIRIHP 231 G+ + I + L+ L + + QN AG L I Sbjct: 178 FGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 232 TGEFSSVQDLARLIVSPPGSTELIYLGDIAHIEKDYDETPDVLYHNRGEAALSLGISFSS 291 F + ++ ++ + ++ L D+A +E + + N G+ A LGI ++ Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN-GKPAAGLGIKLAT 295 Query: 292 GVNVVEVGKSVSERLAELESQRPIGMNLDTVYNQSLAVDDTVNGFLINLLESIAIVIAVL 351 G N ++ K++ +LAEL+ P GM + Y+ + V +++ + L E+I +V V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 352 LLFMG-LRSGLLMGLILLLTILGTFIVMKVLGIELQLISLGALIIALGMLVDNAIVVTEG 410 LF+ +R+ L+ + + + +LGTF ++ G + +++ +++A+G+LVD+AIVV E Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 411 ILIGLRRGKTR-LEAAKQIVTQTQWPLLGATVIAIIAFAPIGLSQNAAGEFCRSLFQVLM 469 + + K EA ++ ++Q Q L+G ++ F P+ + G R ++ Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 470 ISLFISWITAITLTPFFCHLLFKDAPADD-EEQDPYKGWFFSLYRASLTFA-------LR 521 ++ +S + A+ LTP C L K A+ E + + GWF + + S+ L Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 522 FRIASILLVGAMLVTAVIGFGHIKNVFFPASNTPIFFVDIWMPEGTDIKGTERFTADIEQ 581 +L+ ++ V+ F + + F P + +F I +P G + T++ + Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 582 LLLKQAEEQHSGLKHLTTVIG-------QGAQRFVLPYQPEKGYPAFAQLIIEMEDLASL 634 LK + ++ + TV G Q A + +P + + Sbjct: 596 YYLKNEKA---NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSA--EAVIHRA 650 Query: 635 KVYMSELERQLNQRFPQAQYRFKNMENGPSPAAKIEARFYGDDPEVLRALGAQAEAIFHA 694 K+ + ++ F + ++ + + +A Sbjct: 651 KMELGKIRDGFVIPFNMP--AIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 695 EPSMDGVRHDWRNQVPLIRPQLQNAQARETGISKQDLDNALLINFSGKQIGLYRETSHLL 754 S+ VR + + ++ +A+ G+S D++ + G + + + + Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 755 PIVARAPAEERLQADSLWKLQIWSSEHSTFVPATQVVSQFETQWENPLVKRRDRMRMLAV 814 + +A A+ R+ + + KL + S + VP + + + +P ++R + + + + Sbjct: 769 KLYVQADAKFRMLPEDVDKLYV-RSANGEMVPFSAFTT-SHWVYGSPRLERYNGLPSMEI 826 Query: 815 LADPKLGSD-ETADSVLRKVKDKVEAISIPAGYHLEWGGEYETAGEAQTAVFSSIPLGYL 873 + G+ A +++ + K +PAG +W G + + + + ++ Sbjct: 827 QGEAAPGTSSGDAMALMENLASK-----LPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 874 AMFLITVFLFNSVRQPLVIWFTVPLALIGVSAGLLIFDAPFSFMALLGLLSLSGMVIKNG 933 +FL L+ S P+ + VPL ++GV +F+ ++GLL+ G+ KN Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 934 IVLVDQIN-LELDEGKPAYIALVDSSVSRVRPVMMAAITTMLGMIPLIPDAFFGS----- 987 I++V+ L EGK A + + R+RP++M ++ +LG++PL GS Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNA 1001 Query: 988 MAITIIFGLGFASLLTLIVLPVMYSL 1013 + I ++ G+ A+LL + +PV + + Sbjct: 1002 VGIGVMGGMVSATLLAIFFVPVFFVV 1027 Score = 74.1 bits (182), Expect = 2e-15 Identities = 44/219 (20%), Positives = 96/219 (43%), Gaps = 13/219 (5%) Query: 813 AVLADPKLGSDETADSVLRKVKDKVEAI--SIPAGYHLEWGGEYETAGEAQTAVFSSIPL 870 A KL + A + +K K+ + P G ++ Y+T Q ++ + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQG--MKVLYPYDTTPFVQLSIHEVVKT 343 Query: 871 GYLAMFL--ITVFLF-NSVRQPLVIWFTVPLALIGVSAGLLIFDAPFSFMALLGLLSLSG 927 + A+ L + ++LF ++R L+ VP+ L+G A L F + + + G++ G Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 928 MVIKNGIVLVDQINLELDEGKPAYIALVDSSVSRVR-PVMMAAITTMLGMIPL-----IP 981 +++ + IV+V+ + + E K + S+S+++ ++ A+ IP+ Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 982 DAFFGSMAITIIFGLGFASLLTLIVLPVMYSLAFNIKPN 1020 A + +ITI+ + + L+ LI+ P + + Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>cloacin#Cloacin signature. Length = 551 Score = 26.2 bits (57), Expect = 0.039 Identities = 16/70 (22%), Positives = 23/70 (32%), Gaps = 1/70 (1%) Query: 40 AKNAAVKATTGVSGRCTPEKAAERTAKDAKDAVGDAKDKVTDSVSDKVDDIKPDDKLSD- 98 A A +S K E + A++ + D K+K D D P K + Sbjct: 414 AAKEKSDADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKDYGHDYHPAPKTENI 473 Query: 99 KAADALKQDK 108 K LK Sbjct: 474 KGLGDLKPGI 483
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.5 bits (79), Expect = 0.001 Identities = 26/140 (18%), Positives = 49/140 (35%), Gaps = 22/140 (15%) Query: 412 GEILGIE---HKQELVDLHRANGRNVVQGDASDTDFWEKLDRAPNLELVLLAMPHHAGNL 468 +I+G+E ++ ANG ++VQG S + + + +A Sbjct: 209 NQIVGVEVSVQDGGTYNITMANGYSLVQG--STARQLAAVPSSADPSRTTVAYVDGTAG- 265 Query: 469 FAVEQLKKLNYQGKLSAIV--------QYGDDAASLRSSGVHSVYNLYEA-------AGA 513 +E +KL G L I+ Q + L + + ++A AG Sbjct: 266 -NIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGE 324 Query: 514 GFVDHVVHELLPDSETKADA 533 F +L +++ K D Sbjct: 325 DFFAIGKPAVLQNTKNKGDV 344
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.031 Identities = 11/41 (26%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 124 LAAGLSSSGALVVAFGTAISDSSQLHLSPMAVAQLAQRGEY 164 A GLS+S A +A++ L +SP++ +A + + Sbjct: 296 AAQGLSTSAAAAGLIASAVT----LAISPLSFLSIADKFKR 332
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 557 bits (1437), Expect = 0.0 Identities = 315/348 (90%), Positives = 333/348 (95%), Gaps = 1/348 (0%) Query: 1 MFKKLRGIFSNDLSIDLGTANTLIYVRDEGIVLNEPSVVAIRGERSSSGQKSVAAVGTEA 60 M KK RG+FSNDLSIDLGTANTLIYV+ +GIVLNEPSVVAIR +R+ S KSVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGS-PKSVAAVGHDA 59 Query: 61 KQMLGRTPGNIQAIRPMKDGVIADFYVTEKMLQHFIKQVHNNSFFRPSPRVLVCVPVGAT 120 KQMLGRTPGNI AIRPMKDGVIADF+VTEKMLQHFIKQVH+NSF RPSPRVLVCVPVGAT Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESAMGAGAREVYLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAIISLN 180 QVERRAIRESA GAGAREV+LIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA+ISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GVVYSSSVRIGGDKFDDAIINYVRRNYGSLIGEATAERIKHTIGTAYPGDEVLEIEVRGR 240 GVVYSSSVRIGGD+FD+AIINYVRRNYGSLIGEATAERIKH IG+AYPGDEV EIEVRGR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTLNSNEILEALQEPLSGIVSAVMVALEQSPPELASDISERGMVLTGGGAL 300 NLAEGVPR FTLNSNEILEALQEPL+GIVSAVMVALEQ PPELASDISERGMVLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLMQETGIPVMVADDPLTCVARGGGKALEMIDMHGGDLFSEE 348 LR+LDRLLM+ETGIPV+VA+DPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 33.7 bits (77), Expect = 3e-04 Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 8 RIARSSRGFTLVEMVTVILILGIL 31 R RGFTL+E++ VI+I+G+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVL 25
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 37.6 bits (87), Expect = 1e-05 Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 4/58 (6%) Query: 21 KQQGFTLIELVVGMLVIAIAIVM-LSSMLFPQADRAAKTLHRVKSA-ELA--HSVMNE 74 +Q+GFTL+E+++ +L++ ++ M L + + D AA+TL R ++ + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTG 59
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 39.9 bits (93), Expect = 9e-07 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Query: 8 RQFGFTLVELVTTIILIGILSVTVLPRLFNQSSYSAFSLRNEFMAELRQVQQKALNNTDR 67 RQ GFTL+E++ ++L+G+ + VL SA F A+LR VQQ+ L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQT-GQ 60 Query: 68 CYRVVVSATGYQVSQFASR 86 + V V +Q +R Sbjct: 61 FFGVSVHPDRWQFLVLEAR 79
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 44.9 bits (106), Expect = 1e-08 Identities = 14/31 (45%), Positives = 23/31 (74%) Query: 2 MKRQQGFTLIELVVVIIILGILAVTAAPKFI 32 +Q+GFTL+E++VVI+I+G+LA P + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.3 bits (102), Expect = 8e-08 Identities = 15/36 (41%), Positives = 27/36 (75%) Query: 4 KQNGFSLIELVIVIVILGLLAATAIPRFLNVTDDAE 39 KQ GF+L+E+++VIVI+G+LA+ +P + + A+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD 41
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 303 bits (778), Expect = e-102 Identities = 119/407 (29%), Positives = 209/407 (51%), Gaps = 6/407 (1%) Query: 1 MPVYQYRGRSGQGQAVTGQLDAASEGAAADMLLARGIIPLEVKV----AKETKSFTLAQL 56 M Y Y+ QG+ G +A S A +L RG++PL V +++ S L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FKRKVGLDELQIFTRQMYSLTRSGIPILRAIAGLSETAHSQRMKDALNDISEQLTAGRPL 116 K ++ +L + TRQ+ +L + +P+ A+ +++ + + + + ++ G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SSAMNQHPDVFDSLFVSMVHVGENTGKLEDAFIQLSGYIEREQETRRRIKAAMRYPIFVL 176 + AM P F+ L+ +MV GE +G L+ +L+ Y E+ Q+ R RI+ AM YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPC-VL 179 Query: 177 IAIALAMV-ILNIMVIPKFAEMFARFGADLPWATKVLIGTSNLFVNYWPLMLVILLGTII 235 +A+A+V IL +V+PK E F LP +T+VL+G S+ + P ML+ LL + Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 236 GIRYWHHTEKGEKQWDKWKLHIPAVGSIIERSTLSRYCRSFSMMLSAGVPMTQALSLVAD 295 R EK + + LH+P +G I +RY R+ S++ ++ VP+ QA+ + D Sbjct: 240 AFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGD 299 Query: 296 AVDNAYMHDKIVGMRRGIESGESMLRVSNQSKLFTPLVLQMVAVGEETGQIDQLLNDAAD 355 + N Y ++ + G S+ + Q+ LF P++ M+A GE +G++D +L AAD Sbjct: 300 VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 356 FYEGEVDYDLKNLTAKLEPILIGIVAAIVLVLALGIYLPMWDMLNVV 402 + E + EP+L+ +AA+VL + L I P+ + ++ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.4 bits (94), Expect = 1e-05 Identities = 38/187 (20%), Positives = 64/187 (34%), Gaps = 13/187 (6%) Query: 70 NSVNPVASSQTQPDNASPQIDTSPLETETTKSTYTTIPTEPTAEMVQVSPSSTEVPAKDM 129 N P + + T D P +TS + + T E + + +T P + Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 130 SASAESAPSVAQSARLNAAQVEP--TSEPRAEPVATNTSTDTSNNAALTQESAQTQAESQ 187 +S + +S R VEP TS VA T T+ NA L+ A+ Q + Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVAL 1273 Query: 188 QVAVKANQADVNANQSEVKIIQTDPKASEPVVPAATQASRQTS---PQASSPASAQAQST 244 V +Q + ++ + + V + T ++ S + S S Q Q Sbjct: 1274 NVGKAVSQ--------HISQLEMNNEGQYNVWVSNTSMNKNYSSSQYRRFSSKSTQTQLG 1325 Query: 245 GQMAIRE 251 I Sbjct: 1326 WDQTISN 1332 Score = 37.4 bits (86), Expect = 1e-04 Identities = 31/169 (18%), Positives = 57/169 (33%), Gaps = 15/169 (8%) Query: 73 NPVASSQTQPDNASPQIDTSPLETETTKSTYTTIPTEPTAEMVQ-----VSPSSTEVPAK 127 NP + Q +DT+ + T E+ + V P + P++ Sbjct: 982 NPEVEKRNQT------VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE 1035 Query: 128 DMSASAESAPSVAQSARLN---AAQVEPTSEPRAEPVATNTSTDTSNNAALTQESAQTQA 184 AE++ +++ N A + + A+ +N +T N S + Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 185 ESQQVAVKANQADVNANQSEVKIIQTDPKASEPVVPAATQASRQTSPQA 233 ++ + A + E + Q PK + V P Q S PQA Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ-SETVQPQA 1143
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 187 bits (476), Expect = 7e-54 Identities = 78/317 (24%), Positives = 144/317 (45%), Gaps = 28/317 (8%) Query: 237 ELKETLSAIIGDTGGGRQVVVT--PQAGLVTIRAYPNELRQVRAFLNSAESHLQRQVILE 294 ++ A + +++ Q + + A P+ + + + + + QV++E Sbjct: 292 TMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIR-RPQVLVE 350 Query: 295 AKILEVTLSDGYQQGIQWDNVLGHV---GNTNINFGTSAGAGLS----DKITASLGGVTS 347 A I EV +DG GIQW N + N+ + T+ +++SL S Sbjct: 351 AIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALS 410 Query: 348 ------LSIKGSDFNTMISLLDTQGDVDVLSSPRVTASNNQKAVIKVGTDEYFVTDVSST 401 ++ +++ L + D+L++P + +N +A VG + +T S Sbjct: 411 SFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLT--GSQ 468 Query: 402 TVAGTTPVTTPQVELTPFFSGIALDVTPQIDKDGNVLLHVHPSVIDVKEQTKDIKVSSES 461 T +G T + + GI L V PQI++ +VLL + V V + SS S Sbjct: 469 TTSGDNIFNTVERKTV----GIKLKVKPQINEGDSVLLEIEQEVSSVADAA-----SSTS 519 Query: 462 LELPLAQSEIRESDTVIRAASGDVVVIGGLMKSENTEVVSQVPLLGDIPLVGELFKNRSK 521 +L + R + + SG+ VV+GGL+ ++ +VPLLGDIP++G LF++ SK Sbjct: 520 SDLGATFN-TRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSK 578 Query: 522 QKKKTELIIMLKPTVVG 538 + K L++ ++PTV+ Sbjct: 579 KVSKRNLMLFIRPTVIR 595
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 44.7 bits (105), Expect = 1e-07 Identities = 36/197 (18%), Positives = 73/197 (37%), Gaps = 33/197 (16%) Query: 55 LEEGVKQLSQNIPQLDWLINCIGMLHTE--DKGPEKSVQAVDGDFFLHNIKLNTLPSMVL 112 ++E ++ + + +D L+N G+L ++ +A +N+ Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT--------FSVNSTGVFNA 123 Query: 113 AKHFESALKRSASARFAVVSAKVGSISDNRLGGWYSYRASKAALNMFLKTLSIEWQRTMK 172 ++ + S V + + + +Y +SKAA MF K L +E Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMA---AYASSKAAAVMFTKCLGLELAEYNI 180 Query: 173 HCVVLSLHPGTTDTRLSKP------------------FQQNVPKQKLFTPEYVAQCLVSI 214 C ++S PG+T+T + F+ +P +KL P +A ++ + Sbjct: 181 RCNIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 215 IANATPAQTGSFLAYDG 231 ++ T L DG Sbjct: 239 VSGQAGHITMHNLCVDG 255
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 2e-22 Identities = 26/110 (23%), Positives = 57/110 (51%) Query: 3 RLLIIEDDQALAGVLARRLTRHGFECRLSHDASNALLVAREFCPSHILLDMKLAEANGLS 62 +L+ +DD A+ VL + L+R G++ R++ +A+ ++ D+ + + N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LIVPLRNLLPKVIMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAA 112 L+ ++ P + +++++ + TA++A GA +YL KP D L+ Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Score = 48.3 bits (115), Expect = 3e-09 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 116 NSQASALPEDEIDDSPLSPKRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLK 173 S ALP + D L +E+ I L A +GN A LG++R TL++K+ + Sbjct: 417 ASFGDALPPSGLYDRVL--AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 66.0 bits (161), Expect = 2e-14 Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 24/160 (15%) Query: 3 NIMVTGATGLLGRAVVKQLTAAGHRVIATGF---------SRAEAGIHLL---------- 43 +VTGA G +G V K+L AGH+V+ G S +A + LL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 44 DLTQAAEVEAFIAREQPEVIVHCAAERRPDVSERSPEHALALNLSASQTLAEVAKTHQ-A 102 DL + A E + S +P NL+ + E + ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 103 WLLYISTDYVF-DGTTPPYAE-DAVPNPVNFYGESKLQGE 140 LLY S+ V+ P++ D+V +PV+ Y +K E Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE 159
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 28.3 bits (63), Expect = 0.005 Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 5/56 (8%) Query: 3 KSAIVSILLCAAVLLGAMYFGGWTKHPYVQELTTEIRKASAVIEPKKPSAEAMQDT 58 ++ V IL+ AA + + G + +E TE+RK VI P + E + T Sbjct: 44 RALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRK---VIWPTRQ--ETLHTT 94
>cloacin#Cloacin signature. Length = 551 Score = 28.1 bits (62), Expect = 0.029 Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 11/91 (12%) Query: 16 PVFAASNSSINIAEVDKAASTLNIEKLQQLSTTTQDYEAAYANYRLAIS---------AN 66 V+ + + ++ +V + N + QQ T EAA NY A + A Sbjct: 282 AVYVSVSDVLSPDQVKQRQDEEN--RRQQEWDATHPVEAAERNYERARAELNQANEDVAR 339 Query: 67 VMGQKTLAEQALTSAQTSLEAINNTQADAES 97 ++ A Q S ++ L+A N T ADA + Sbjct: 340 NQERQAKAVQVYNSRKSELDAANKTLADAIA 370
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.006 Identities = 59/352 (16%), Positives = 114/352 (32%), Gaps = 65/352 (18%) Query: 10 QKIAWVYLINLAFYLIPLFVTPYPSWQIGLILAVLIPFIYSYFWAYRCHTRVAYRPISVM 69 Q I W F L+ +P I I L+ + + AYR R + Sbjct: 16 QGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLT--HAYR---SFIKRQGWLK 70 Query: 70 LLLAIAITPINPGSISLFTFASFFIGFFYPLRVSLLSWFGILALLFLLNHFSQFNNLYFP 129 L + I + P + LL++ + F L ++ F Sbjct: 71 LNMGQIILRVLPACV----VIGMVWFVANTSIWRLLAFINTKPVAFTL---PLALSIIFN 123 Query: 130 LYGSALVFGVGMLGIAEQKRYQHRLKERQSAQEISTLATMVERERIARDLHDIMGH---- 185 + ++ + G K Y+ E + +A+M + ++ I H Sbjct: 124 VVVVTFMWSLLYFGWHFFKNYKQA--EIDQWK----MASMAQEAQLMALKAQINPHFMFN 177 Query: 186 SLSSIALKAELAEKLLAKQEYQLATTQLQELGQIARESLSQIRH----------TVSDYK 235 +L++I L ++ A L L ++ R SL V Y Sbjct: 178 ALNNIRA--------LILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSY- 228 Query: 236 HKGLASCVTQLCHSLR-DKGIAVELLG-ELPKLSARAESQLGLVLTELVNNILRH----- 288 L Q L+ + I ++ ++P + ++ LV N ++H Sbjct: 229 ---LQLASIQFEDRLQFENQINPAIMDVQVPPM----------LVQTLVENGIKHGIAQL 275 Query: 289 SSASQCRIQFREQADSLIVDVQDN----APTSPIIEGNGLTGIRERLTSLGG 336 + ++ + ++ ++V++ + G GL +RERL L G Sbjct: 276 PQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYG 327
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 8e-20 Identities = 30/117 (25%), Positives = 51/117 (43%), Gaps = 1/117 (0%) Query: 2 HILLAEDQAMVRGALAALLTLAGGFTITQASNGDEALNLLKQQHFDLLLTDIEMPGRTGL 61 IL+A+D A +R L L+ AG + + SN + DL++TD+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 ELATWLKEQHSHTKVVVITTFGRAGYIKRAIEAGVGGFLLKDAPSETLVHAIQQVIA 118 +L +K+ V+V++ +A E G +L K L+ I + +A Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.7 bits (90), Expect = 5e-05 Identities = 33/149 (22%), Positives = 57/149 (38%), Gaps = 17/149 (11%) Query: 202 QAKQALEIAAAGNHNLLMLGPPGTGKTMLASRIMALLPILNYE-EALEVAAIHSVAGINI 260 + + L + L++ G GTGK ++A + N A+ +AAI Sbjct: 148 EIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI-------- 199 Query: 261 KPQDFLKRPFRAPHHTSSSISLVGGGSIPKPGEISLAHRGVLFLDEVAEFPRKVLDCLRE 320 P+D ++ H + + G G A G LFLDE+ + P L Sbjct: 200 -PRDLIESELFG--HEKGAFT---GAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLR 253 Query: 321 PMETGEVVISRAAAKLTFLSRFQLIAAMN 349 ++ GE + + S +++AA N Sbjct: 254 VLQQGE--YTTVGGRTPIRSDVRIVAATN 280
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 33.6 bits (77), Expect = 6e-04 Identities = 20/90 (22%), Positives = 31/90 (34%), Gaps = 17/90 (18%) Query: 164 IGYEKAFEQIRTGDVIYCDPP-------YAPLSTTASFTTYVGAGFSLDDQALLARYSRH 216 I E ++ V+ +P Y T T+ D Q R Sbjct: 245 IQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYT----DAQVQ---TVRK 297 Query: 217 MALEQRIPVVISNHDIPLTRELYRGAHLAK 246 +A E+ +P++ IPL R LY A + Sbjct: 298 IAEEEGVPIL---QRIPLARALYWDALVDH 324
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.027 Identities = 16/65 (24%), Positives = 24/65 (36%) Query: 14 ALVERLHHVASYSDQLLVLVGAHGSGKTTLLTALATDFDESNAALVICPMHADNAEIRRK 73 V R+ D +VL G G GK+TL+ L S+ I +I Sbjct: 583 GHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGI 642 Query: 74 ILVQL 78 + +L Sbjct: 643 VAYEL 647
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.002 Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 8/64 (12%) Query: 9 LVGPMGAGKSTIGRHLAQML-----HLEFHDSDQEIEQRTGADIAWVFDVEGEEGFRRRE 63 L G G GKST+ L + H + EQ G +++ FRR + Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAG---IVAYELSEMTAFRRAD 657 Query: 64 AQVI 67 A+ + Sbjct: 658 AEAV 661
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 249 bits (638), Expect = 1e-75 Identities = 99/411 (24%), Positives = 189/411 (45%), Gaps = 38/411 (9%) Query: 306 GDITLRLDDVPWDQALDLILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQEVKELA 365 GD ++ + W A D++ L+K + L + + E N Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 366 PLYSEYLQ----------------INYAKATDIAELLKGADSSLLSPRG----------- 398 ++ + YAKA+D+ E+L G S++ S + Sbjct: 250 QRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKN 309 Query: 399 -SVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWG 457 + +TN ++V +++ ++ R++ LDI QVL+E+ + V+D +LGI+W Sbjct: 310 IIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA 369 Query: 458 VTDQQGSKGTSGTLEGAGSIANGVVPSLDNRLNVNLPAAVTNPTSIAFHVAKLADGTILD 517 + ++ T+ L + +IA + D ++ +L +A+++ IA + Sbjct: 370 NKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN----WA 425 Query: 518 LELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYV-----QSTSSGATSVTFKKAV 572 + L+AL K +I+A+P I T + A G E+P + S + +V K Sbjct: 426 MLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVG 485 Query: 573 LSLRVTPQITPDNRVILDLEITQDSQGKT-VDTPTGPAVAIDTQRIGTQVLVDNGETIVL 631 + L+V PQI + V+L++E S T + +T+ + VLV +GET+V+ Sbjct: 486 IKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVV 545 Query: 632 GGIYQQNLISRVSKVPILGDIPLVGFLFRNTTDKNERQELLIFVTPKIVNE 682 GG+ +++ KVP+LGDIP++G LFR+T+ K ++ L++F+ P ++ + Sbjct: 546 GGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRD 596 Score = 46.8 bits (111), Expect = 2e-07 Identities = 33/175 (18%), Positives = 75/175 (42%), Gaps = 14/175 (8%) Query: 275 SLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLR-LDDVPWDQALDLILQTKGLDKR 333 S +F+ ++ + ++ N ++ +V G IT+R D + +Q L Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVL----D 86 Query: 334 IEGNILMVAPSEELAIRESQNLKNKQEVK--ELAP-----LYSEYLQINYAKATDIAELL 386 + G ++ + L + S++ K + AP + + + + A D+A LL Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 387 KGADSSLLSPRGSVAVDERTNTVLVKDTAEIIENIHRLVEVLDIPIRQVLIESRM 441 + + + + GSV E +N +L+ A +I+ + +VE +D + ++ + Sbjct: 147 RQLNDN--AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPL 199
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 42.8 bits (101), Expect = 1e-06 Identities = 32/156 (20%), Positives = 57/156 (36%), Gaps = 34/156 (21%) Query: 199 VDIGANMTTFCVVESGETTFIREQAFGGELFTQSILSFYGMSY------EQAEKAKIE-- 250 VDIG T V+ + GG+ F ++I+++ +Y AE+ K E Sbjct: 164 VDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIG 223 Query: 251 -------------------GDLPRNY------MFEVLSPFQTQLLQQIKRTLQIYCTSSG 285 +PR + + E L T ++ + L+ Sbjct: 224 SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELA 283 Query: 286 KDKVDY-LVLCGGTSKLEGMANLLTNELGVHTIIAD 320 D + +VL GG + L + LL E G+ ++A+ Sbjct: 284 SDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAE 319
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.005 Identities = 18/132 (13%), Positives = 41/132 (31%), Gaps = 3/132 (2%) Query: 36 QAATKGHEERAFNPQNERTADQTQQQARLLEQNQQQVQDKQQQQQSSQQQSQQQQEKQAP 95 + A + N Q A Q + E + ++ ++ + + + ++ ++ P Sbjct: 1067 EVAKEAKSNVKANTQTNEVA---QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 96 IVAADRALPKTLKVPVRGPAALQRKDIRLKVGQNTPRPANTTANTTTATTRQPMQGESPQ 155 V + + + V+ A R++ + NTTA+T E P Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 156 FYQQVGQRIGQY 167 Sbjct: 1184 TESTTVNTGNSV 1195
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 5e-18 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 3/118 (2%) Query: 14 TKGKILIVDDQPLNIKILHQLFH-EEYEMFMATSGEQALQVCQKMQPDLVLLDIEMPEMT 72 T IL+ DD +L+Q Y++ + ++ + DLV+ D+ MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 73 GYEVCQRLKADPATANIGVIFITAHFDEMEEVKGFQLGAVDFIHKPINPIITSARVKN 130 +++ R+K A ++ V+ ++A M +K + GA D++ KP + + Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 4e-15 Identities = 35/156 (22%), Positives = 68/156 (43%), Gaps = 7/156 (4%) Query: 1287 TLLVVEDNQLNREVIDELLTYEGATVVLAEGGIEGVTQVLDSGDMFDAVIMDMQMPDIDG 1346 T+LV +D+ R V+++ L+ G V + + + D V+ D+ MPD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVMPDENA 62 Query: 1347 LEATRRIRADGRFDQLPILAMTANASQADKQECLEAGMNAHVSKPIDMQQLLPNILRLVG 1406 + RI+ LP+L M+A + + E G ++ KP D+ +L+ I R + Sbjct: 63 FDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 1407 RDAAQFAEPESMHLDAQHNLEGET--LLDDIRLILR 1440 + ++ E L G + + + R++ R Sbjct: 121 EPKRRPSKLED-DSQDGMPLVGRSAAMQEIYRVLAR 155 Score = 61.8 bits (150), Expect = 1e-11 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 1138 LSGYRILVVDDNQITTEILSKILSDYGCVVETASGGYQAIEKVKQATANAQQFDVVLMDW 1197 ++G ILV DD+ +L++ LS G V S + A D+V+ D Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-----AGDGDLVVTDV 55 Query: 1198 RMPDIDGLQTAEMLKNAGTGSYTPLVVMLTAYG 1230 MPD + +K A P++VM +A Sbjct: 56 VMPDENAFDLLPRIKKA--RPDLPVLVM-SAQN 85
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 100 bits (251), Expect = 1e-26 Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 4/133 (3%) Query: 6 SKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLIVLDLMLPGEDGL 65 + ILV DDD +R +L + L GY VR +NA + R + + L+V D+++P E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 SICRRLRQQGSTIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQI 125 + R+++ +P+++++A+ + I E GA DYLPKPF+ EL+ I R + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII----GRAL 119 Query: 126 QDVPGAPAQQEAE 138 + P++ E + Sbjct: 120 AEPKRRPSKLEDD 132
>PF06580#Sensor histidine kinase Length = 349 Score = 47.6 bits (113), Expect = 4e-08 Identities = 19/120 (15%), Positives = 41/120 (34%), Gaps = 24/120 (20%) Query: 325 DCPEALFQGLAIKRVLSNLVENAFRYG------SGWVRISSQFDGKRIGFSVEDNGPGID 378 A+ ++ LVEN ++G G + + D + VE+ G Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL 304 Query: 379 ESQIPKLFQPFTQGDIARGSVGSGLGLA-IIKRIIDRHQGQVTLS-NRTEGGLKAQVWLP 436 ++ +G GL + +R+ + + + + +G + A V +P Sbjct: 305 KNTKE----------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348