PredictBias

		>ENTEROVIROMP#Enterobacterial virulence outer membrane protein

		           signature.

		          Length = 171

		

		 Score = 75.7 bits (186), Expect = 2e-20

		 Identities = 34/106 (32%), Positives = 50/106 (47%), Gaps = 16/106 (15%)

		

		Query: 22  DIKYYSFLAGPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKST 81

		             +YY   AGPAYR+ND+ S YG+VG+ + K +            E   Y          

		Sbjct: 82  KNQYYGITAGPAYRINDWASIYGVVGVGYGKFQ----------TTEYPTY---KHDTSDY 128

		

		Query: 82  DFAYAAGVIINPWGNMSVNVGYEGTKADIYGKHSVNGFTVGVGYRF 127

		            F+Y AG+  NP  N++++  YE ++        V  +  GVGYRF

		Sbjct: 129 GFSYGAGLQFNPMENVALDFSYEQSRI---RSVDVGTWIAGVGYRF 171

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 37.1 bits (86), Expect = 4e-05

		 Identities = 18/82 (21%), Positives = 31/82 (37%), Gaps = 12/82 (14%)

		

		Query: 160 AAGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTD 219

		           A   GK+ + G           IK  E+ I        ++V  G+SV+ G  +  + +  

		Sbjct: 84  ATANGKLTHSGRSK-------EIKPIENSIV-----KEIIVKEGESVRKGDVLLKLTALG 131

		

		Query: 220 AASVRLHFQIRYRATAIDPLRY 241

		           A +  L  Q       ++  RY

		Sbjct: 132 AEADTLKTQSSLLQARLEQTRY 153

		

		

		>TYPE3OMGPROT#Type III secretion system outer membrane G protein

		           family signature.

		          Length = 607

		

		 Score =  448 bits (1155), Expect = e-154

		 Identities = 158/536 (29%), Positives = 271/536 (50%), Gaps = 54/536 (10%)

		

		Query: 34  YVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALIERLSAQMGLIWYD 93

		           YVA  E+LR       +      +VS     K +SG F+   P   ++ +++   L+WY 

		Sbjct: 38  YVAKGESLRDLLTDFGANYDATVVVSDKINDK-VSGQFEHDNPQDFLQHIASLYNLVWYY 96

		

		Query: 94  DGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGD-GNGTFYVSGPPV 152

		           DG  +YI+ +SE+ + LI L++    E    L++SG++  R+  + D  N   YVSGPP 

		Sbjct: 97  DGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWEPRFGWRPDASNRLVYVSGPPR 156

		

		Query: 153 YVDLVVNAAKLMEQNSD--GIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLS 210

		           Y++LV   A  +EQ +     + G   + I  L     +DRT   R +++  PG+A +L 

		Sbjct: 157 YLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDEVAAPGVATILQ 216

		

		Query: 211 TLLNNNIKQSTGVNVLSEISSRQQLKNVSRMPPFPGAEEDDDLQVEKIISTAGAPETDDI 270

		            +L++              ++ QQ+   ++  P                  A    +   

		Sbjct: 217 RVLSD--------------ATIQQVTVDNQRIPQ-----------------AATRASAQA 245

		

		Query: 271 QIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTDLEQLGADWSG 330

		           ++ A P  N+++V+ +  ++   ++L+  LD P   IE++L I+DI+   L +LG DW  

		Sbjct: 246 RVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRV 305

		

		Query: 331 TIKIGSSLSASFNNSG----------SISTLDG---TQFIATIQALAQKRRAAVVARPVV 377

		            I+ G++       +G            S +D       +A +  L  +  A VV+RP +

		Sbjct: 306 GIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTL 365

		

		Query: 378 LTQENIPAIFDNNRTFYTKLVGERTAELDEVTYGTMISVLPRFAARN---QIELLLNIED 434

		           LTQEN  A+ D++ T+Y K+ G+  AEL  +TYGTM+ + PR   +    +I L L+IED

		Sbjct: 366 LTQENAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIED 425

		

		Query: 435 GNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTYESRKIPILGSIPFI 494

		           GN+   + + ++ +P + RT++ T+ARV  G+SL+IGG  RD  +    K+P+LG IP+I

		Sbjct: 426 GNQ-KPNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYI 484

		

		Query: 495 GKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDE 550

		           G LF  +       VR+F+IEPR IDE + ++   A  + + +   +    EI+++

		Sbjct: 485 GALFRRKSELTRRTVRLFIIEPRIIDEGIAHHL--ALGNGQDLRTGILTVDEISNQ 538

		

		

		>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE)

		           signature.

		          Length = 372

		

		 Score =  240 bits (613), Expect = 2e-78

		 Identities = 128/321 (39%), Positives = 195/321 (60%)

		

		Query: 14  AREVSRLEDIITEDNEDIEAEMPKMRDDPAGKEARFLQATDEMSAALTQFMKKKIYEEQL 73

		           +R+ S  +     D +  E +       P  +  +F+Q+TDEMSAAL QF  ++ YE++ 

		Sbjct: 16  SRQASHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSAALAQFRNRRDYEKKS 75

		

		Query: 74  ANFLDGEEYVLEDQPIEKTDKVMEALKAATTHDYEVYSFAKKLFPDESDLVVVLRAILRK 133

		           +N  +  E VLED+ + K  ++++ +        +    A+ LFPD SDLV+VLR +LR+

		Sbjct: 76  SNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFPDPSDLVLVLRELLRR 135

		

		Query: 134 KQISENVRLNAEALLRKVNQETTKKFINSGINSALKAKLFGQALSLNPKLLRASYRQFLM 193

		           K + E VR   E+LL+ V ++T  K + +GIN ALKA+LFG+ LSL P LLRASYRQF+ 

		Sbjct: 136 KDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQ 195

		

		Query: 194 AEDDAVDTYVEWIGSYGYQNRMLVTKFIKETLFSDINALDASCSSLEFGMFLNKLSQLLS 253

		           +E   V+ Y +WI SYGYQ R++V  FI+ +L +DI+A DASCS LEFG  L +L+QL  

		Sbjct: 196 SESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSRLEFGQLLRRLTQLKM 255

		

		Query: 254 LQSAEALFLKTLMNNPIIKKFISAEDYWIFFLISLIKFPETAEELLNNALVTLPADANYK 313

		           L+SA+ LF+ TL++    K F + E  W+  ++SL++ P   + LL + +       ++K

		Sbjct: 256 LRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHK 315

		

		Query: 314 DKTLLLKAIYSGCTNLPFSLF 334

		           +    L+  Y  C  +P SLF

		Sbjct: 316 EHASFLQIFYQVCKAIPSSLF 336

		

		

		>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature.

		          Length = 1291

		

		 Score = 31.2 bits (70), Expect = 0.019

		 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 3/60 (5%)

		

		Query: 597 EIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLAL---SGINIPIKDIILLGSVDIRR 653

		           EI +R+  G    A  T L L ASE     +N +++L   + +N+    + L+G+V + R

		Sbjct: 202 EINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYDGATLNLASNSVKLMGNVWMGR 261

		

		

		>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M

		           signature.

		          Length = 147

		

		 Score = 42.8 bits (100), Expect = 7e-08

		 Identities = 41/142 (28%), Positives = 74/142 (52%)

		

		Query: 2   LSKVNRLIRRTAQSLAACEASLQKLNAEKEKLAEKERLYDMQLKNLQSLLDMKELLGEVV 61

		           L+++  L RR     + CE+ L +   E  +L  +E     Q+  L+ LLD        +

		Sbjct: 4   LTRIKVLQRRCTVFHSQCESILLRYQDEDRRLQVEEEAIVEQIAGLKLLLDTLRAENRQL 63

		

		Query: 62  FRQDIFYSLRKVTVIQQQIAEINLEKQKIAERRKILNKEIVQQQAQRKHWWLKGEKYDRL 121

		            R++I+  LRK +++++QI ++ L+  +I E+R  L K+  + Q + K+W  K   Y R 

		Sbjct: 64  SREEIYALLRKQSIVRRQIKDLELQIIQIQEKRSELEKKREEFQEKSKYWLRKEGNYQRW 123

		

		Query: 122 KKRIKKQLLNQMLYQDELEQEE 143

		             R K+  + + + Q+E E EE

		Sbjct: 124 IIRQKRLYIQREIQQEEAESEE 145

		

		

		>SSPANPROTEIN#Salmonella invasion protein InvJ signature.

		          Length = 336

		

		 Score = 48.6 bits (115), Expect = 5e-10

		 Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 3/75 (4%)

		

		Query: 31  ENELTYQFQRWGQNHTVRILESSEG-IRLKPSDTLVSDRLHEAQHNDVTAQRWVLTEQDE 89

		           ++ LTY+FQRWG +++V I     G   L PS+T V  RLH+   N    QRW LT +D+

		Sbjct: 260 DSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNG-NPQRWHLT-RDD 317

		

		Query: 90  RQGQRHQPHEEQENE 104

		           +Q  + Q H +Q  E

		Sbjct: 318 QQNPQQQQHRQQSGE 332

		

		

		>TYPE3OMOPROT#Type III secretion system outer membrane O protein

		           family signature.

		          Length = 303

		

		 Score =  156 bits (395), Expect = 1e-47

		 Identities = 91/292 (31%), Positives = 136/292 (46%), Gaps = 13/292 (4%)

		

		Query: 35  KENGEDVALLMPEFSAKWLPIAEESGSWSGWVLLREIFPLISAELAGMALMPETERLIGE 94

		           + +G +  L  P     W+ +++    WS W+   +    +S  LAG A+    E L+  

		Sbjct: 23  QRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWLEHVSPALAGAAVSAGAEHLVVP 82

		

		Query: 95  WLSLSSSPLNLKYPELKYNRLCVGKVFDGVLSPAQPLIRIWTGELNLWLDKVTVCQYENA 154

		           WL+ +  P  L  P L   RLCV     G   P   L+ I +    LW + +        

		Sbjct: 83  WLAATERPFELPVPHLSCRRLCVENPVPGSALPEGKLLHIMSDRGGLWFEHLPELPAVGG 142

		

		Query: 155 PTLDKKSLYWPIHFVIGFSKTCYRTIVDIEVGDVLLISNNMAYAVIYNTKICDLIYPEEL 214

		                K L WP+ FVIG S T    +  I +GDVLLI  + A            +Y    

		Sbjct: 143 GRP--KMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTSRA-----------EVYCYAK 189

		

		Query: 215 KMADHFQYEEDFETDDFDIKKSESEIYDENDEQMINSFEELPVKIEFVLGKKIMNLYEID 274

		           K+    + E     +  DI+  E E       + +    +LPVK+EFVL +K + L E++

		Sbjct: 190 KLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAELE 249

		

		Query: 275 ELCAKRIISLLPESEKNIEIRVNGALTGYGELVEVDDKLGVEIHSWLSGHNN 326

		            +  ++++SL   +E N+EI  NG L G GELV+++D LGVEIH WLS   N

		Sbjct: 250 AMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESGN 301

		

		

		>TYPE3IMPPROT#Type III secretion system inner membrane P protein

		           family signature.

		          Length = 224

		

		 Score =  226 bits (577), Expect = 2e-77

		 Identities = 151/223 (67%), Positives = 181/223 (81%), Gaps = 5/223 (2%)

		

		Query: 1   MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQQVPSNMTLNGVALLLS 60

		           M N ISLIA+L+  TLLPFIIASGTCF+KFSIVFV+VRNALGLQQ+PSNMTLNGVALLLS

		Sbjct: 1   MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60

		

		Query: 61  MFVMMPVGKEIYYNSQNENLSFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQK 120

		           MFVM P+  + Y   ++E+++FN+++S+   V+ G+ GY+ YLIKYS+ ELV FFE  Q 

		Sbjct: 61  MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120

		

		Query: 121 VNSSEDNEEIIDDD-----NISIFSLLPAYALSEIKSAFIIGFYIYLPFVVVDLVISSVL 175

		                +  E +  D       SIF+LLPAYALSEIKSAF IGFY+YLPFVVVDLV+SSVL

		Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180

		

		Query: 176 LTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLS 218

		           L LGMMMMSPVTISTPIKL+LFVA+DGWT+LSKGLILQY D++

		Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIA 223

		

		

		>TYPE3IMQPROT#Type III secretion system inner membrane Q protein

		          family signature.

		          Length = 86

		

		 Score = 78.7 bits (194), Expect = 4e-23

		 Identities = 59/86 (68%), Positives = 73/86 (84%)

		

		Query: 1  MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQEQTLPFGVKLLCVSICF 60

		          MDD+VFAGN+ALYL+L++S  P  VAT +GLLVGLFQTVTQLQEQTLPFG+KLL V +C 

		Sbjct: 1  MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60

		

		Query: 61 FLMSGWYGEKLYSFGIEMLNLAFARG 86

		          FL+SGWYGE L S+G +++ LA A+G

		Sbjct: 61 FLLSGWYGEVLLSYGRQVIFLALAKG 86

		

		

		>TYPE3IMSPROT#Type III secretion system inner membrane S protein

		           family signature.

		          Length = 354

		

		 Score =  310 bits (796), Expect = e-106

		 Identities = 112/340 (32%), Positives = 185/340 (54%), Gaps = 5/340 (1%)

		

		Query: 2   ANKTEKPTQKKLQDASKKGQILKSRDLTVSVIMLVG--TLYLGYVFDVHHIMSILEYILD 59

		             KTE+PT KK++DA KKGQ+ KS+++  + +++     L     +   H   ++    +

		Sbjct: 3   GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62

		

		Query: 60  HNAKPDIWD---YFKAMGIGWLKTIIPFLLVCMFTTILVSWFQSKMQLATEAVKLKFDSL 116

		            +  P           + + +     P L V     I     Q    ++ EA+K     +

		Sbjct: 63  QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122

		

		Query: 117 NPVNGLKRIFGLKTVKEFVKAILYIIFFALEIKVFWSNHKSLLFKTLDGDIISLLSDWGE 176

		           NP+ G KRIF +K++ EF+K+IL ++  ++ I +    +   L +     I  +    G+

		Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182

		

		Query: 177 MLFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQEVKREYKEQEGNPEIKSKRRERH 236

		           +L  L++ C    +++ I D+  EY+ ++K++KM K E+KREYKE EG+PEIKSKRR+ H

		Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242

		

		Query: 237 QEILSEQLKSDVSNSRLMIANPTHIAIGIYFKPHLSPIPLISVRETNEVALAVRKYAKEI 296

		           QEI S  ++ +V  S +++ANPTHIAIGI +K   +P+PL++ + T+     VRK A+E 

		Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302

		

		Query: 297 GIPIITDKKLARKIYATHRRYDYVSFENIDEILRLLLWLE 336

		           G+PI+    LAR +Y       Y+  E I+    +L WLE

		Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLE 342

		

		

		>FLGMRINGFLIF#Flagellar M-ring protein signature.

		          Length = 559

		

		 Score = 34.6 bits (79), Expect = 3e-04

		 Identities = 22/126 (17%), Positives = 49/126 (38%), Gaps = 5/126 (3%)

		

		Query: 4   ISLLLFILLLCGCKQQE-LLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTD 62

		           +++++ ++L         L ++L  Q    ++A L + NI     +       I V    

		Sbjct: 35  VAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGA---IEVPADK 91

		

		Query: 63  FASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIV 122

		                  L    LP    +    +   +    S  +E+     A+E  L ++++ +  + 

		Sbjct: 92  VHELRLRLAQQGLPKGGAVGFE-LLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVK 150

		

		Query: 123 SSRVHV 128

		           S+RVH+

		Sbjct: 151 SARVHL 156

		

		

		>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD

		           chaperone signature.

		          Length = 168

		

		 Score = 75.0 bits (184), Expect = 1e-19

		 Identities = 25/143 (17%), Positives = 58/143 (40%), Gaps = 5/143 (3%)

		

		Query: 22  ALSKGENLALLHGLTPDILDRIYAYAFDYHEKGNVTDAEIYYKLLCIYAFENHEYLKGFA 81

		            L  G  +A+L+ ++ D L+++Y+ AF+ ++ G   DA   ++ LC+    +  +  G  

		Sbjct: 18  FLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLG 77

		

		Query: 82  SVCQSKKKYQQAYDLYKLSYNYSPYDDYSVIYRMGQCQIGAKNIDNAMQCFYH----IIN 137

		           +  Q+  +Y  A   Y          +    +   +C +    +  A    +     I +

		Sbjct: 78  ACRQAMGQYDLAIHSYSYGAIMDI-KEPRFPFHAAECLLQKGELAEAESGLFLAQELIAD 136

		

		Query: 138 NCEDASVKSKAQAYIELLTDNSE 160

		             E   + ++  + +E +    E

		Sbjct: 137 KTEFKELSTRVSSMLEAIKLKKE 159

		

		

		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

		          Length = 800

		

		 Score = 29.3 bits (65), Expect = 0.038

		 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%)

		

		Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265

		              P L  N +  A+ +E  K   YE+GK I+L +         +   ++       + +

		Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206

		

		Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321

		               S++F   LE   K   I  I++ L E        F+Y         ++L   D+F 

		Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266

		

		Query: 322 TNTKILKEGIEK 333

		              K+ K G EK

		Sbjct: 267 YMNKLEKGGFEK 278

		

		

		>cloacin#Cloacin signature.

		          Length = 551

		

		 Score = 36.2 bits (83), Expect = 1e-04

		 Identities = 17/31 (54%), Positives = 18/31 (58%)

		

		Query: 266 GSSSSSSGGGSSGGGSGGGFSGGGGSSGGGG 296

		           GS S    GG SG G+GGG    GG SG GG

		Sbjct: 49  GSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79

		

		

		

		 Score = 36.2 bits (83), Expect = 1e-04

		 Identities = 14/33 (42%), Positives = 17/33 (51%)

		

		Query: 266 GSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGAS 298

		           GS     GG   G G G G SGGG  +GG  ++

		Sbjct: 51  GSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83

		

		

		

		 Score = 35.5 bits (81), Expect = 2e-04

		 Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 5/39 (12%)

		

		Query: 266 GSSSSSSGGGSS-----GGGSGGGFSGGGGSSGGGGASG 299

		            S ++  GGGS      GGGSG G  GG G+SGGG  +G

		Sbjct: 40  SSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78

		

		

		

		 Score = 30.8 bits (69), Expect = 0.007

		 Identities = 17/38 (44%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

		

		Query: 266 GSSSSSSGGGSS----GGGSGGGFSGGGGSSGGGGASG 299

		           G +S  SG  S     GGGSG G   GGGS  G G   

		Sbjct: 31  GGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGN 68

		

		

		

		 Score = 29.7 bits (66), Expect = 0.016

		 Identities = 13/35 (37%), Positives = 18/35 (51%)

		

		Query: 264 RKGSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGAS 298

		           R  ++ + S  G+  GG  G   GGG S G G +S

		Sbjct: 7   RGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSS 41

		

		

		

		 Score = 28.1 bits (62), Expect = 0.048

		 Identities = 11/27 (40%), Positives = 13/27 (48%), Gaps = 2/27 (7%)

		

		Query: 272 SGGGSSGGGSGGGFSGGGGSSGGGGAS 298

		           SG G+ GG    G  GG G+ G   A 

		Sbjct: 60  SGHGNGGGNGNSG--GGSGTGGNLSAV 84

		

		

		>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein

		           signature.

		          Length = 533

		

		 Score = 27.2 bits (60), Expect = 0.047

		 Identities = 17/74 (22%), Positives = 29/74 (39%), Gaps = 12/74 (16%)

		

		Query: 36  NASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDE 95

		           +AS  ++ ++ Q   D +  L  S  GY            +  +  N+   +    P  +

		Sbjct: 294 SASIEQIQSKIQELGDTLEELRDSFDGY------------INNAFVNQIHLNFVMPPQAQ 341

		

		Query: 96  QKLQAWQQAQAQVT 109

		           Q+    QQ QAQ T

		Sbjct: 342 QQQGQGQQQQAQAT 355

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 29.4 bits (66), Expect = 0.029

		 Identities = 21/103 (20%), Positives = 45/103 (43%), Gaps = 8/103 (7%)

		

		Query: 48  GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVA 107

		           G++++ + +         G ++D+F  R ++  ++    +   +MAT P LWV+   ++ 

		Sbjct: 46  GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105

		

		Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147

		             IT      +    A + + D     E+ +  G+M    G G

		Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  104 bits (261), Expect = 4e-29

		 Identities = 72/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%)

		

		Query: 11  MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEN-QGVEVD 69

		           M+   ++GK A +TG   G+G+A A  LA  GA++    +  +  E        +    +

		Sbjct: 1   MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60

		

		Query: 70  FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 129

		               D+    A  +I A      G +DILVN AG+ +   +      +W+    VN T  

		Sbjct: 61  AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120

		

		Query: 130 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189

		           F  S   +K M+ ++SG I+ + S  + +      AY+++K A   FTK    EL +YNI

		Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180

		

		Query: 190 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 240

		           + N ++PG   TD+  +L    N    Q +          IP  +     D+  A +FL 

		Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239

		

		Query: 241 SQASNYVNGHLLVVDGG 257

		           S  + ++  H L VDGG

		Sbjct: 240 SGQAGHITMHNLCVDGG 256

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 30.6 bits (69), Expect = 0.011

		 Identities = 16/84 (19%), Positives = 36/84 (42%), Gaps = 12/84 (14%)

		

		Query: 276 IIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGS 335

		           I+ATA+G++ ++G +         IK      ++      ++V+E + V+ G  +  + +

		Sbjct: 82  IVATANGKLTHSGRSK-------EIKP---IENSIV--KEIIVKEGESVRKGDVLLKLTA 129

		

		Query: 336 TGTSSTRLHFEIRYKGKSVNPLRY 359

		            G  +  L  +       +   RY

		Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRY 153

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score =  389 bits (1000), Expect = e-131

		 Identities = 140/373 (37%), Positives = 203/373 (54%), Gaps = 39/373 (10%)

		

		Query: 350 YQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVLKQVEMVAQSDSTVLILG 409

		             E+  +  R + E      +L +   +   ++GRS AM  + + +  + Q+D T++I G

		Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167

		

		Query: 410 ETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRF 469

		           E+GTGKEL+ARA+H+   R N   V +N AA+P  L+ES+LFGHE+GAFTGA  +  GRF

		Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227

		

		Query: 470 ELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRDLKKMV 529

		           E A+  +LFLDE+GDMP++ Q +LLRVLQ+ E+  +G    I++DVR++AATN+DLK+ +

		Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287

		

		Query: 530 ADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAFTFKIARRLGRNIDSIPAETLRTL 589

		               FR DLYYRLNV P+ LPPLR+R EDIP L + F  + A + G ++     E L  +

		Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELM 346

		

		Query: 590 SNMEWPGNVRELENVIERAVLLTRGNVLQLSL---------------------PDIALPE 628

		               WPGNVRELEN++ R   L   +V+   +                       +++ +

		Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406

		

		Query: 629 PETPPAATVVAQEG--------------EDEYQLIVRVLKETNGVVAGPKGAAQRLGLKR 674

		                     A  G              E EY LI+  L  T G       AA  LGL R

		Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQI---KAADLLGLNR 463

		

		Query: 675 TTLLSRMKRLGID 687

		            TL  +++ LG+ 

		Sbjct: 464 NTLRKKIRELGVS 476

		

		

		>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature.

		          Length = 1147

		

		 Score = 27.0 bits (59), Expect = 0.012

		 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 8/75 (10%)

		

		Query: 12  IDGNQAKVD--VCGIQRDVDLTLVGSCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLD 69

		           I GNQ + D    G+  D  L      ++NG+P  G W+ + + F   + ++ ++ D  +

		Sbjct: 171 IIGNQIRTDQKFMGV-FDESLKERQEAEKNGEPTGGDWLDIFLSF---IFDKKQSSDVKE 226

		

		Query: 70  ALQN--MFDVEPDVG 82

		           A+    +  V+PD+ 

		Sbjct: 227 AINQEPVPHVQPDIA 241

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 28.4 bits (63), Expect = 0.035

		 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%)

		

		Query: 2   TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 56

		           T++ E+AK AGV++  +           +        +     +E     P      L  

		Sbjct: 32  TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91

		

		Query: 57  KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 89

		                L   VT      +   E++FH      E

		Sbjct: 92  ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score =  373 bits (960), Expect = e-127

		 Identities = 125/388 (32%), Positives = 195/388 (50%), Gaps = 33/388 (8%)

		

		Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLK 198

		           I A   GA               +I +  ++          ++     ++G S  M ++ 

		Sbjct: 91  IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150

		

		Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258

		           + +  +  +DL ++I+GE+GTGKELVA+A+H+   R   P V +N AA+P  + ESELFG

		Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210

		

		Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 318

		           H KGAFTGA +  +G+FE A+ GTLFLDEIG++ +  Q +LLRVLQ G+   VG    +R

		Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270

		

		Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378

		            DVR++AATN+DL++ +  G FR DL++RL+V PL +PPLR+R +D+  L  +F +Q   

		Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329

		

		Query: 379 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433

		           ++GL        A  L++ + +PGNVRELE+ + R   L        E+I      E   

		Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389

		

		Query: 434 FAFPEVTLPPPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476

		               +       ++    V++N+R                       +   I  AL    

		Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449

		

		Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504

		            N    A +L  +   L +  + LG+  

		Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477

		

		

		>PRTACTNFAMLY#Pertactin virulence factor family signature.

		          Length = 910

		

		 Score =  230 bits (587), Expect = 3e-64

		 Identities = 216/888 (24%), Positives = 347/888 (39%), Gaps = 95/888 (10%)

		

		Query: 629  NDGGTLDVREKGSATGIQQSSQGAL-VATTRATRVTGTRADGVAFSIEQGAANNILLANG 687

		            N+   +   E+     IQ S  G +  A+    +V+G +A G+     +  A  +   NG

		Sbjct: 37   NNQSIVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGILL---ENPAAELQFRNG 93

		

		Query: 688  GVLT----VESDTSSDKTQVNTGGREIVKTKATATGTTLTGGEQ----IVEGVANETTIN 739

		             V +     +         V     ++V   AT      T  +      V G   + +I 

		Sbjct: 94   SVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLANVGDTWDDDGIALYVAGEQAQASIA 153

		

		Query: 740  DGGIQTVS-------ANGEAIKTTINEGGTLTVNDNGKATDIVQNSGAALQTSTANGIEI 792

		            D  +Q          AN    ++ I +GG           + +  S   L+ +    +  

		Sbjct: 154  DSTLQGAGGVQIERGANVTVQRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPA 213

		

		Query: 793  SGTHQY------------GTFSISGNLATNMLLENGGNLLVLAGTEARDSTVG------- 833

		            SG                G     G  A    ++     L  A     D+  G       

		Sbjct: 214  SGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGA 273

		

		Query: 834  -KGGAMQNQGQDSATKVNSGGQYTL---GRSKDEFQALARAEDLQVA-----GGTAIVYA 884

		              GGA+              G Y +   G S +  Q++  A +L  A     G    V  

		Sbjct: 274  VPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGARVTVSG 333

		

		Query: 885  GTLA--DASVSGATGSLSLMTPRDNVTPVKLEGAIRITDSATLTIGNGVDTTLADLTAA- 941

		            G+L+    +V    G+     P+     + L+        A L         L     A 

		Sbjct: 334  GSLSAPHGNVIETGGARRFA-PQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGAD 392

		

		Query: 942  SRGSVWLNSNNSCAGTSNCEYR---------------VNSLLLNDGNVYLSAQTA----- 981

		            ++G +      S  GTS                    V+SL +++    ++  +      

		Sbjct: 393  AQGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALR 452

		

		Query: 982  ---------APATTNGIYNTLTTNELSGSGNFYLHTNVAGSRGDQLVVNNNATGNFKIFV 1032

		                           G +  LT N L+GSG F ++        D+LVV  +A+G  +++V

		Sbjct: 453  LASDGSVDFQQPAEAGRFKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWV 512

		

		Query: 1033 QDTGVSPQSDDAMTLVKT-GGGDASFSLGNTGGFVDLGTYEYVLKSDGNSNWNLTNDVKP 1091

		            +++G  P S + + LV+T  G  A+F+L N  G VD+GTY Y L ++GN  W+L     P

		Sbjct: 513  RNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAP 572

		

		Query: 1092 NPDPNPNPNPNPKPDPKPDPKPDPKPDPTPE-PTPTPVPEKRITPSTAAVLNMA--ATLP 1148

		                     P PKP P+P P+P   P P PE P P P   + ++ +  A +N        

		Sbjct: 573  ---------PAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLAS 623

		

		Query: 1149 LVFDAELNSIRERLNIMKASPHNNNVWGATYNTRNNVTTDAGAGFEQTLTGMTVGIDSPN 1208

		             ++ AE N++ +RL  ++ +P     WG  +  R  +   AG  F+Q + G  +G D   

		Sbjct: 624  TLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAV 683

		

		Query: 1209 DIPEGIATLGAFMGYSHSHIGFDRGGHGSVGSYSLGGYASWEHESGFYLDGVVKLNRFES 1268

		             +  G   LG   GY+    GF   G G   S  +GGYA++  +SGFYLD  ++ +R E+

		Sbjct: 684  AVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLEN 743

		

		Query: 1269 NVAGKMSSGGAANGSYHSNGLGGHIETGMRFT-DGNWNLTPYASLTGFTADNPEYHLSNG 1327

		            +     S G A  G Y ++G+G  +E G RFT    W L P A L  F A    Y  +NG

		Sbjct: 744  DFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANG 803

		

		Query: 1328 MESKSVDTRSIYRELGATLSYNMRLGNGMEIEPWLKAAVRKEFVDDNRVKVNNDGNFVND 1387

		            +  +     S+   LG  +   + L  G +++P++KA+V +EF     V  N   +   +

		Sbjct: 804  LRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAH-RTE 862

		

		Query: 1388 LSGRRGIYQAGIKASFSSTLSGHLGVGYSHGAGVESPWNAVAGVNWSF 1435

		            L G R     G+ A+     S +    YS G  +  PW   AG  +S+

		Sbjct: 863  LRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910

		

		

		>TONBPROTEIN#Gram-negative bacterial tonB protein signature.

		          Length = 239

		

		 Score = 63.5 bits (154), Expect = 1e-13

		 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 2/62 (3%)

		

		Query: 338 SPLPEPEPEPEPEPEPEP-EPEPEPEPEPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEP 395

		           +P     P+    P     EPEPEPEP PEP  E P    +P+P+P+P+P+P  + + +P

		Sbjct: 51  TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110

		

		Query: 396 IR 397

		            R

		Sbjct: 111 KR 112

		

		

		

		 Score = 62.7 bits (152), Expect = 3e-13

		 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 2/67 (2%)

		

		Query: 330 IETSLDFSSPLPEPEPEPEPEPEPEPEP-EPEPEPEPEPEPEPE-PEPEPEPEPEPEPEP 387

		               +  +   P     P+    P     EPEPEPEP PEP  E P    +P+P+P+P+P

		Sbjct: 41  PAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 100

		

		Query: 388 EPEPEPE 394

		           +P  + +

		Sbjct: 101 KPVKKVQ 107

		

		

		

		 Score = 61.9 bits (150), Expect = 4e-13

		 Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 1/58 (1%)

		

		Query: 341 PEPEPEPEPEPEPEPEPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIR 397

		           P PEP  EPEPEPEP PEP  E P    +P+P+P+P+P+P  + + +P+ + +P   R

		Sbjct: 63  PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120

		

		

		

		 Score = 61.9 bits (150), Expect = 5e-13

		 Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 1/66 (1%)

		

		Query: 339 PLPEPEPEPEPEPEPEPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIR 397

		           P PEP  EPEPEPEP PEP  E P    +P+P+P+P+P+P  + + +P+ + +P      

		Sbjct: 63  PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPA 122

		

		Query: 398 SSLKEN 403

		           S  +  

		Sbjct: 123 SPFENT 128

		

		

		

		 Score = 43.8 bits (103), Expect = 5e-07

		 Identities = 12/60 (20%), Positives = 26/60 (43%)

		

		Query: 339 PLPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIRS 398

		             P+  P    +P+P+P+P+P+P  + + +P+ + +P       P     P        +

		Sbjct: 80  EPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTAT 139

		

		

		

		 Score = 41.5 bits (97), Expect = 3e-06

		 Identities = 14/66 (21%), Positives = 28/66 (42%)

		

		Query: 339 PLPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIRS 398

		           P   P    +P+P+P+P+P+P  + + +P+ + +P       P     P          +

		Sbjct: 82  PKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAA 141

		

		Query: 399 SLKENT 404

		           + K  T

		Sbjct: 142 TSKPVT 147

		

		

		

		 Score = 38.0 bits (88), Expect = 3e-05

		 Identities = 11/67 (16%), Positives = 26/67 (38%)

		

		Query: 339 PLPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIRS 398

		           P+   +P+P+P+P+P+P  + + +P+ + +P       P     P             + 

		Sbjct: 86  PVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKP 145

		

		Query: 399 SLKENTE 405

		                + 

		Sbjct: 146 VTSVASG 152

		

		

		

		 Score = 32.7 bits (74), Expect = 0.002

		 Identities = 10/65 (15%), Positives = 22/65 (33%)

		

		Query: 339 PLPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPIRS 398

		             P+P+P+P+P+P  + + +P+ + +P       P     P                   

		Sbjct: 90  EKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSV 149

		

		Query: 399 SLKEN 403

		           +    

		Sbjct: 150 ASGPR 154

		

		

		>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein

		           signature.

		          Length = 522

		

		 Score = 29.0 bits (64), Expect = 0.014

		 Identities = 15/46 (32%), Positives = 32/46 (69%), Gaps = 2/46 (4%)

		

		Query: 27  EICGTKIALERRSKEREKAEKAEKAAEKKRRREEQKQKDKLKIQKL 72

		           E+   K ALE+  + +E+A+KA+K  +K+ +R+E++ K++  ++ L

		Sbjct: 140 ELEEQKKALEKEKEAKEQAQKAQK--DKREKRKEERAKNRANLENL 183

		

		

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 26.3 bits (58), Expect = 0.032

		 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%)

		

		Query: 4   KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61

		           K +    AVL  + AG   LER ++     Q + +  + VS+  +  GMT  ++  A   

		Sbjct: 69  KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122

		

		Query: 62  PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88

		             MSD    N    +     G  G+T 

		Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 28.1 bits (62), Expect = 0.024

		 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%)

		

		Query: 34   QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATA 93

		            Q  +  ++ + +     +  E+ Q        Q    K  AT    +KA+ +  +     

		Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122

		

		Query: 94   DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153

		             K   Q    + +S  +Q Q     + +  V      I +         D  Q   + + 

		Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177

		

		Query: 154  NMTE 157

		            N+ +

		Sbjct: 1178 NVEQ 1181

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 50.5 bits (121), Expect = 2e-09

		 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%)

		

		Query: 63  VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118

		           ++DG++ DFF    +++  +       F R         P G      R      + AG 

		Sbjct: 76  MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135

		

		Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169

		               +++EP A A    L   +  G  VVDIGGGTT +A++    V YS+    GG

		Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191

		

		

		>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase

		           signature.

		          Length = 572

		

		 Score =  614 bits (1585), Expect = 0.0

		 Identities = 202/567 (35%), Positives = 331/567 (58%), Gaps = 8/567 (1%)

		

		Query: 117 LYGNVLASGVGVGTLTLLQSDSLDSYRAIPA-SAQDSTRLEHSLATLAEQLNQQLRERDG 175

		           + G   +SGV +    +    ++D  +      + +  +L  +L    E+L     + + 

		Sbjct: 5   ITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEA 64

		

		Query: 176 ----ESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIIRNMEQVCAKLSASASDYL 231

		               +   I +AHL ++ D E    I+  +  +      A+    +   +   +  ++Y+

		Sbjct: 65  SMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYM 124

		

		Query: 232 RERVSDIRDISEQLL-HITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMIL 290

		           +ER +DIRD+S+++L H+   E      +   + T+++AEDLTPS    L+ + + G   

		Sbjct: 125 KERAADIRDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFAT 182

		

		Query: 291 EKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCGVLAINPNDAVSGYYQV 350

		           +  GRTSH+ I++R+  IP + G          G   ++D   G++ +NP +     Y+ 

		Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEE 242

		

		Query: 351 AQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPGAFANGAEGVGLFRTEMLY 410

		            +   +K++++ A+   + + ++D   +++AANIGT  +  G  ANG EG+GL+RTE LY

		Sbjct: 243 KRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY 302

		

		Query: 411 MDRDSEPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVR 470

		           MDRD  P E+EQFEAY++V+     KP++ RT+DIGGDK + YL +P+E NPFLG+RA+R

		Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIR 362

		

		Query: 471 IYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHGLDQILWVKGEIQKAIVELKRDGLRHA 530

		           +  E   +FRTQLRA+LRA+++GN ++M PM+  L+++   K  +Q+   +L  +G+  +

		Sbjct: 363 LCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422

		

		Query: 531 ETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMTQYLYAVDRNNPRVSPLYNPITPSF 590

		           ++I +GIMVE+PS     + F  EVDFFSIG+ND+ QY  A DR N RVS LY P  P+ 

		Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482

		

		Query: 591 LRMLQQIVTTAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIPAVKSQLRQLD 650

		           LR++  ++  AH  GKWVG+CGE+ G+   +PLLLGLGLDE SMS+  I   +SQL +L 

		Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLS 542

		

		Query: 651 SEACRELARQACECRSAQEIEALLTAF 677

		            E  +  A++A    +A+E+E L+   

		Sbjct: 543 KEELKPFAQKALMLDTAEEVEQLVKKT 569

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 55.2 bits (133), Expect = 5e-11

		 Identities = 21/132 (15%), Positives = 57/132 (43%), Gaps = 6/132 (4%)

		

		Query: 2   KVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDG 61

		            +++ +D+   +  L+  +        V    +   + +++     D +  D+ +P  + 

		Sbjct: 5   TILVADDDAAIRTVLNQALS--RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62

		

		Query: 62  V-LLAQNISQFAHKPFIVFITAWK--EHAVEAFELEAFDYILKPYQESRITGMLQKLEAA 118

		             LL +        P +V ++A      A++A E  A+DY+ KP+  + + G++ +  A 

		Sbjct: 63  FDLLPRIKKARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121

		

		Query: 119 WQQQQTSSTPAA 130

		            +++ +     +

		Sbjct: 122 PKRRPSKLEDDS 133

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  223 bits (570), Expect = 3e-70

		 Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 11/207 (5%)

		

		Query: 348 RAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIE 407

		              ++  MA +A+L AL+++INPHF+FNALN I + I  +P  AR+++ +LS  +RY++ 

		Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209

		

		Query: 408 LKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEV-NCCIPSLLIQPLVENAIV 466

		             +  Q+ +  EL  +  Y+ +   +F D+L     I+  + +  +P +L+Q LVEN I 

		Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIK 269

		

		Query: 467 HGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHR 526

		           HGI      G + +   +    V + V +TG        E            GL NV  R

		Sbjct: 270 HGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------STGTGLQNVRER 321

		

		Query: 527 VKLLYGE--GLHIRRLEPGTEIAFYIP 551

		           +++LYG    + +   +        IP

		Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVLIP 348

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 76.4 bits (188), Expect = 2e-16

		 Identities = 30/105 (28%), Positives = 51/105 (48%)

		

		Query: 890 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNVDGFE 949

		           +IL+ADD    R +L + L+  GYDV   ++       ++    DL++TDV MP+ + F+

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 950 LTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLD 994

		           L  ++++    LP+  ++A        K    G    L KP  L 

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 49.1 bits (117), Expect = 3e-09

		 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%)

		

		Query: 4   IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63

		           ++ DD       +   L +   ++    +   +  + +     D+V+ DV +P  N   +

		Sbjct: 7   LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65

		

		Query: 64  LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123

		           L  ++K +    ++++SA+N                          + AI+A++ G   +

		Sbjct: 66  LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101

		

		Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148

		              PF L      +    + L    ++ 

		Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 78.7 bits (194), Expect = 5e-18

		 Identities = 63/412 (15%), Positives = 122/412 (29%), Gaps = 96/412 (23%)

		

		Query: 13  RRKYFSLLAIVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71

		           RR       I+ F+  +   +    ++E + + +      G +  I    +  V  +  K

		Sbjct: 55  RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113

		

		Query: 72  DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97

		           +   VR+GD+L+ L    A     K                                   

		Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173

		

		Query: 98  ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136

		                             K   +    Q  +  L   +  AE  +   +   Y+      

		Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233

		

		Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182

		             R+     L  +  I+K              +      S    + + I + K    LV 

		Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293

		

		Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233

		                     L +    +        +     + + I++PV+  + Q  V   G  V+  

		Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353

		

		Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292

		           ++LM +VP    + V A  +   +  + +GQ+  I  +       F     G  +G    

		Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404

		

		Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340

		              +         + +V  V   +S++   L       PL  G+++TA I T

		Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score =  120 bits (302), Expect = 1e-31

		 Identities = 97/408 (23%), Positives = 169/408 (41%), Gaps = 25/408 (6%)

		

		Query: 19  VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78

		           + I L + +F  +L+  + NV++P I+           WV T+F +  +I   V G+L+ 

		Sbjct: 15  ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74

		

		Query: 79  RIGELRLFLLSVTFFSLSSLMCSLSIN-LDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137

		           ++G  RL L  +      S++  +  +   +LI  R +QG  A     L   ++ R  P 

		Sbjct: 75  QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134

		

		Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197

		           E R  A  L    V +    GP +GG I     W   +L+ +PM  I+    L  L  +E

		Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192

		

		Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVIFLISLVIWES 257

		                   ++ G+ L+ +G+  +  ML        F +S  I   +VSV+  +  V    

		Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241

		

		Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317

		              +P +D  L K+  F IG++     +   +G + ++P ++++    +    G      

		Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301

		

		Query: 318 GIMPLLISPLIG-----RYGNKIDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQ 372

		           G M ++I   IG     R G    + + VTF     +V +   S     T  F  II+  

		Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL----SVSFLTASFLLETTSWFMTIIIVF 357

		

		Query: 373 FFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420

		              G +       ++TI  S L   +     S+ NF   LS   G ++

		Sbjct: 358 VLGGLSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403

		

		

		>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family

		           signature.

		          Length = 1024

		

		 Score = 28.0 bits (62), Expect = 0.037

		 Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 4/129 (3%)

		

		Query: 93  GQARYQSLAAAEATGGLGSTATGNQLAAIAPTLGQNWLS--GQMNNYNNLANIGLGALTG 150

		           G+   Q + A  A  GL ++A    L A A TL  + LS     + +     I   +   

		Sbjct: 284 GKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRF 343

		

		Query: 151 QANAGQNYANNVSQLYQQQAAASAANANKPSGLQSFATGAIGGAASGAMIGSAVPVIGTG 210

		           +   G +  + ++  +++  A  A+     + L S +   I  AA+ +++G+ V  +   

		Sbjct: 344 KK-LGYDGDSLLAAFHKETGAIDASLTTISTVLASVS-SGISAAATTSLVGAPVSALVGA 401

		

		Query: 211 IGALAGGVI 219

		           +  +  G++

		Sbjct: 402 VTGIISGIL 410

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 34.9 bits (80), Expect = 4e-04

		 Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 7/120 (5%)

		

		Query: 229 LSFAEISSVV------FILMSVYMVAKSQNSNGLQYDA-LFIPSMAFSILVFSFNGGIIS 281

		           LS AEI SV+       +++  Y+     +  G  Y   + +  ++ S L  SF     S

		Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348

		

		Query: 282 KIISNKVMILLGDASFSFYLVHTIVISTLSKFFNVSGLGAISVIKFIVMALFASLFISIM 341

		             ++  ++ +LG  SF+  ++ TIV S+L +    +G+  ++   F+      ++   ++

		Sbjct: 349 WFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 27.8 bits (62), Expect = 0.011

		 Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 7/66 (10%)

		

		Query: 57  IMLAQHALLIAISSDLNAYGVVCEFDWN----DGNGQEGWPSMDGSEGIRITD---IDTS 109

		           + LA   L I +  D   +G   +F       DG GQ       G+    IT+   +D  

		Sbjct: 22  VRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALILDHW 81

		

		Query: 110 GIFNSD 115

		           GI  +D

		Sbjct: 82  GIVKAD 87

		

		

		>YERSSTKINASE#Yersinia serine/threonine protein kinase signature.

		          Length = 732

		

		 Score = 31.2 bits (70), Expect = 0.007

		 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 7/54 (12%)

		

		Query: 122 HIHSKGLMHFDIKPNNIMISNRN-EAMLSDFGLSQLVNE------ESRAAPEFG 168

		           H+   G++H DIKP N++    + E ++ D GL     E      ES  APE G

		Sbjct: 260 HLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELG 313

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 30.0 bits (67), Expect = 5e-04

		 Identities = 9/24 (37%), Positives = 14/24 (58%)

		

		Query: 10 GVGIPEVAKACGVSERAVYKWLKN 33

		             + E+AKA GV+  A+Y   K+

		Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKD 54

		

		

		>FLGMOTORFLIG#Flagellar motor switch protein FliG signature.

		          Length = 344

		

		 Score = 27.8 bits (62), Expect = 0.039

		 Identities = 17/77 (22%), Positives = 27/77 (35%), Gaps = 11/77 (14%)

		

		Query: 2   KNIAAQMVNFDREQM-----------RRIANNMPEQYDEKPQVQQVAQIINGVFSQLLAT 50

		            N+A ++   DR              +++A+   E Y     V  V +IIN    +    

		Sbjct: 165 TNVARRIALMDRTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224

		

		Query: 51  FPASLANRDQNELNEIR 67

		              SL   D     EI+

		Sbjct: 225 IIESLEEEDPELAEEIK 241

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 27.1 bits (60), Expect = 0.004

		 Identities = 10/30 (33%), Positives = 17/30 (56%), Gaps = 4/30 (13%)

		

		Query: 10  DMLVEAYE----NQTEVARILNCSRNTVRK 35

		            +++ A      NQ + A +L  +RNT+RK

		Sbjct: 439 PLILAALTATRGNQIKAADLLGLNRNTLRK 468

		

		

		>SHIGARICIN#Ribosome inactivating protein family signature.

		          Length = 289

		

		 Score =  144 bits (364), Expect = 4e-43

		 Identities = 53/277 (19%), Positives = 115/277 (41%), Gaps = 35/277 (12%)

		

		Query: 4   ILFKWVLCLLLGFSSVSYSREFTIDFSTQQSYVSSLNSIRTEISTPLEHISQGTTSVSVI 63

		           +    +L L L   +V     F +  +T  SY   ++++R  +    +        + ++

		Sbjct: 6   VFSLLILTLFLTAPAVEGDVSFRLSGATSSSYGVFISNLRKALPYERK-----LYDIPLL 60

		

		Query: 64  NHTPPGSYFAVDIRGLDVYQARFDHLRLIIEQNNLYVAGFVNTATNTFYRFSDFT----- 118

		             T PGS     I  L  Y    + + + I+  N+YV G+   A +T Y F++ +     

		Sbjct: 61  RSTLPGSQRYALIH-LTNYAD--ETISVAIDVTNVYVMGY--RAGDTSYFFNEASATEAA 115

		

		Query: 119 HISVPGVT-TVSMTTDSSYTTLQRVAALERSGMQISRHSLVSSYLALMEFSGNTMTRDAS 177

		                     V++    +Y  LQ  A   R  + +   +L S+   L  ++ N+    A+

		Sbjct: 116 KYVFKDAKRKVTLPYSGNYERLQIAAGKIRENIPLGLPALDSAITTLFYYNANS----AA 171

		

		Query: 178 RAVLRFVTVTAEALRFRQIQREFRQALSETAPVYTMTPGDVDLTLNWGRISNVLPEYRGE 237

		            A++  +  T+EA R++ I+++  + + +T   +  +   + L  +W  +S  +      

		Sbjct: 172 SALMVLIQSTSEAARYKFIEQQIGKRVDKT---FLPSLAIISLENSWSALSKQIQIASTN 228

		

		Query: 238 DGV----------RVGRISFNNISA--ILGTVAVILN 262

		           +G           +  R++  N+ A  +   +A++LN

		Sbjct: 229 NGQFETPVVLINAQNQRVTITNVDAGVVTSNIALLLN 265

		

		

		>PF06291#Lambda prophage Bor protein

		          Length = 102

		

		 Score =  163 bits (413), Expect = 3e-56

		 Identities = 89/97 (91%), Positives = 91/97 (93%)

		

		Query: 1   MKKMLLATALALLITGCAQQTFTVQNKQTAVAPKETITHHFFVSGIGQKKTVDAAKICGG 60

		           MKKML + ALA+LITGCAQQTFTV NK TAV PKETITHHFFVSGIGQKKTVDAAKICGG

		Sbjct: 6   MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65

		

		Query: 61  TENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 97

		            ENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ

		Sbjct: 66  AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 30.6 bits (69), Expect = 0.008

		 Identities = 17/91 (18%), Positives = 29/91 (31%), Gaps = 25/91 (27%)

		

		Query: 179 KILKAEQALDRNIARIESIERSLL----------------TLDVLAETAPKLRADRERIN 222

		           K ++A   L    +++E IE  +L                 LD L +T   +      + 

		Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319

		

		Query: 223 AARDKLRAETDILTNQRRGVVTPVSDIVSSL 253

		              ++          Q   +  PVS  V  L

		Sbjct: 320 KNEERQ---------QASVIRAPVSVKVQQL 341

		

		

		>CHANLCOLICIN#Channel forming colicin signature.

		          Length = 522

		

		 Score = 33.1 bits (75), Expect = 0.004

		 Identities = 21/101 (20%), Positives = 46/101 (45%), Gaps = 10/101 (9%)

		

		Query: 613 QEVAAQQQALQQQQAELQMREMAGRVAKLEADAARAHAAAQRDNASAQREVALTQGQRYV 672

		           +E  A ++A Q+  AE + +E+     + +A+  R    A+ +    +R  AL++  + V

		Sbjct: 141 KEAEAAEKAFQE--AEQRRKEIE----REKAETERQLKLAEAEE---KRLAALSEEAKAV 191

		

		Query: 673 DALNQAHTAEIITGVQNMEQEQDVLQQQMLYTLQQRMNEMS 713

		           +   +   +   + V  M+ E   L  ++  ++  R  EM 

		Sbjct: 192 EIAQKK-LSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMK 231

		

		

		>CHANLCOLICIN#Channel forming colicin signature.

		          Length = 522

		

		 Score = 34.7 bits (79), Expect = 0.001

		 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 4/111 (3%)

		

		Query: 130 KNTQATQSKESAAASAKSASDSAK--TATSRAAEAGQKATDATEAATRAVTAAGNAEESS 187

		           K TQA Q+  + AA+   A   A     T R  +   +A     + T + T   +A  ++

		Sbjct: 63  KKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAA 122

		

		Query: 188 TRAGESEKAAGADAEKARQHAEKARLAQESAGEILKRAEAATVSAEEARRM 238

		            +A +         EKAR+ AE A  A + A +  +R E     AE  R++

		Sbjct: 123 MQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQ--RRKEIEREKAETERQL 171

		

		

		>ENTEROVIROMP#Enterobacterial virulence outer membrane protein

		           signature.

		          Length = 171

		

		 Score =  110 bits (276), Expect = 2e-32

		 Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 31/167 (18%)

		

		Query: 79  SGYEGKDKNPQGINIRYRYEITDD-FGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPA 137

		           S  +G+     G N++YRYE  +   GVI SFT+T                     K+  

		Sbjct: 35  SDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTE--------------------KSRT 74

		

		Query: 138 ASARTDIRANYWSLLAGPSWRVNQYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNS 197

		           AS+    +  Y+ + AGP++R+N + S+Y + G+G  K             +   +  + 

		Sbjct: 75  ASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQT----------TEYPTYKHD 124

		

		Query: 198 TKKNSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGITAGIGLKF 244

		           T     ++ AG QFN  E+V LD +YE S           AG+G +F

		Sbjct: 125 TSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF 171

		

		

		>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature.

		          Length = 52

		

		 Score = 33.6 bits (77), Expect = 2e-06

		 Identities = 13/47 (27%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

		

		Query: 1  MSQKSLIT--VTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCK 45

		          + + SL+   + +C+T++   ++   SLCE R      E AAF+  +

		Sbjct: 3  LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYE 49

		

		

		>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP

		           signature.

		          Length = 245

		

		 Score = 28.6 bits (64), Expect = 0.018

		 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 3/56 (5%)

		

		Query: 68  MVTSFT---AVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEP 120

		           M+TSFT    V  + R       A P Q  L +     F  M+PVI ++Y    +P

		Sbjct: 60  MMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQP 115

		

		

		>AUTOINDCRSYN#Autoinducer synthesis protein signature.

		          Length = 216

		

		 Score = 34.8 bits (80), Expect = 6e-05

		 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%)

		

		Query: 1  MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52

		          M+E  D++H+ LS ++   L  LR   F               +   D +    +  ++ 

		Sbjct: 1  MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56

		

		Query: 53 GWKNDELVAYARILKSDDD 71

		          G K++ ++   R +++   

		Sbjct: 57 GIKDNTVICSLRFIETKYP 75

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 32.0 bits (72), Expect = 0.007

		 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 17/74 (22%)

		

		Query: 24  PGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYKKDSGTILFQGKEIDFHSAK 83

		           PG K  D   +         L G  G GKSTL+  L G+         F     D  + K

		Sbjct: 591 PGCKF-DYSVV---------LEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGK 633

		

		Query: 84  EALENGISMVHQEL 97

		           ++ E    +V  EL

		Sbjct: 634 DSYEQIAGIVAYEL 647

		

		

		>AEROLYSIN#Aerolysin signature.

		          Length = 493

		

		 Score = 29.2 bits (65), Expect = 0.029

		 Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 1/35 (2%)

		

		Query: 359 QRNTIKTQNYQ-TRDPQVFAAGDIVEGDKTVVYAV 392

		            +  IK  N+    DP  F  GD+ + D+ +V  V

		Sbjct: 189 DKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTV 223

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 51.4 bits (123), Expect = 4e-09

		 Identities = 62/407 (15%), Positives = 142/407 (34%), Gaps = 29/407 (7%)

		

		Query: 22  RVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGAGLLGLTAGALLCGPLS 81

		           +++I   ++      +   +    PDI   +         +  A +L  + G  + G LS

		Sbjct: 14  QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73

		

		Query: 82  DRFGRKRVIELCVFLFGALSLASAFS-PDLQTLVFLRFLTGLGLGGAMPNTIT-MTSEYL 139

		           D+ G KR++   + +    S+           L+  RF+ G G   A P  +  + + Y+

		Sbjct: 74  DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AAAFPALVMVVVARYI 132

		

		Query: 140 PARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLPLMLFVALLVVLPE 199

		           P   RG    L+     +G   G  +   +   I W  +L++  +  + +   L+ +L +

		Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPF-LMKLLKK 191

		

		Query: 200 SPRWQVRRQLPQAVI-----------AKTVSAITRERYVDTHFYLIESASVTKGSIRQLF 248

		             R +    +   ++             + S       V +    ++             

		Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPG 251

		

		Query: 249 MGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASRVTAAFQI-------G 301

		           +G+ +P  ++  +   +    +    S +P ++     D+   S       I        

		Sbjct: 252 LGKNIPF-MIGVLCGGIIFGTVAGFVSMVPYMMK----DVHQLSTAEIGSVIIFPGTMSV 306

		

		Query: 302 GTLGALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDG-LWLMALAIFGTGIGISGS 360

		              G +  G+L+D+  P  VL +     ++  +      +   W M + I     G+S +

		Sbjct: 307 IIFGYIG-GILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFT 365

		

		Query: 361 QVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNF 407

		           +  ++ + ++    Q    G+S  N         G    G ++++  

		Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412

		

		

		

		 Score = 39.1 bits (91), Expect = 3e-05

		 Identities = 41/200 (20%), Positives = 78/200 (39%), Gaps = 5/200 (2%)

		

		Query: 251 RQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASRVTAAFQIGGTLGALALG 310

		           R   I + L ++ F S+L   +L+  +P + N         + V  AF +  ++G    G

		Sbjct: 11  RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70

		

		Query: 311 VLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTAT 370

		            L D+    R+L     I     V+  +      L+ +A F  G G +     +  + A 

		Sbjct: 71  KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130

		

		Query: 371 LYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAVMLTLL 430

		             P ++R        +I   G  VG   GG M+A    +  L  I      I+ + +  L

		Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGG-MIAHYIHWSYLLLI----PMITIITVPFL 185

		

		Query: 431 ITVVRQSTSVPDSLPRAGVV 450

		           + ++++   +       G++

		Sbjct: 186 MKLLKKEVRIKGHFDIKGII 205

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 28.9 bits (64), Expect = 0.033

		 Identities = 13/80 (16%), Positives = 32/80 (40%), Gaps = 2/80 (2%)

		

		Query: 79  NVALALLDERERNQQYIKRRDQENEEIALTVGKLRVELEAAKSKLNEQREYYEGVIADGS 138

		           N + A   + +  +      + E  ++      L    ++ +  L+  RE  + + A+  

		Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333

		

		Query: 139 KRIAELEKQCAEWERKALSN 158

		           K   E + + +E  R++L  

		Sbjct: 334 K--LEEQNKISEASRQSLRR 351

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 24.1 bits (52), Expect = 0.037

		 Identities = 7/23 (30%), Positives = 11/23 (47%)

		

		Query: 10  VGTITFVYSVTKRGWVFPGLSVI 32

		           VG + F+   T     F  +SV+

		Sbjct: 209 VGIVFFMLFTTSYSISFLIVSVL 231

		

		

		>FLGMOTORFLIG#Flagellar motor switch protein FliG signature.

		          Length = 344

		

		 Score = 27.1 bits (60), Expect = 0.009

		 Identities = 14/51 (27%), Positives = 21/51 (41%)

		

		Query: 17  RRIANNMPEQYDEKPQVQQVAQIINGVFRQLLATFPASLANRDQNELNEIR 67

		           +++A+   E Y     V  V +IIN   R+       SL   D     EI+

		Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIK 241

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 30.8 bits (69), Expect = 0.006

		 Identities = 23/119 (19%), Positives = 44/119 (36%), Gaps = 17/119 (14%)

		

		Query: 134 KEVITRTVKVTNVGKPSVAEERSEITPATAIKVTP-------------TSGTVAKGKTTT 180

		           ++ IT TVKV    KP   +E +  T    +  +              TS T  K   + 

		Sbjct: 675 QDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734

		

		Query: 181 LT--VSFEPESATDKTFRAVSADPSKATI--SVKDMTITVNGVATGKVQIPVVSGNGQF 235

		               V+ + ++   + F  ++ D     I  +     +    +  G+V +    GNG++

		Sbjct: 735 RVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKY 793

		

		

		>LCRVANTIGEN#Low calcium response V antigen signature.

		          Length = 326

		

		 Score = 34.3 bits (78), Expect = 0.002

		 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%)

		

		Query: 529 DLWKAESQYAVL-KEAATKRQLSEQEKSLLAHKDETLEYKRQLAELG---DKVEYQKRLN 584

		           +++KA ++Y +L K   T  Q+   EK +++ KD      ++   LG   +   Y K  N

		Sbjct: 205 EIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNN 264

		

		Query: 585 ELAQQAVRFEEQQSAKQAAISAKARGLTDRQAQRESEAQRL 625

		           EL+  A    ++       +S K   L+D  ++  S  + L

		Sbjct: 265 ELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEAL 305

		

		

		>ENTEROVIROMP#Enterobacterial virulence outer membrane protein

		           signature.

		          Length = 171

		

		 Score =  141 bits (358), Expect = 3e-45

		 Identities = 63/195 (32%), Positives = 99/195 (50%), Gaps = 29/195 (14%)

		

		Query: 7   VILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG-SDDLNGINVKYRYEFMDA-LG 64

		           +   + +  V A T  ++    ST++ GY  A ++  G  + + G N+KYRYE  ++ LG

		Sbjct: 4   IACLSALAAVLAFTAGTSVAATSTVTGGY--AQSDAQGQMNKMGGFNLKYRYEEDNSPLG 61

		

		Query: 65  LITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRV 124

		           +I SF+Y        T  S T    D  +N+++ + AGP+ R+N+W S Y + GV Y + 

		Sbjct: 62  VIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKF 113

		

		Query: 125 STFYGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYEGSGSG 184

		            T        T+     HD          S+   ++GAG+QFNP E+VA+D +YE S   

		Sbjct: 114 QT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYEQSRIR 156

		

		Query: 185 DWRTDGFIVGVGYKF 199

		                 +I GVGY+F

		Sbjct: 157 SVDVGTWIAGVGYRF 171

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 38.9 bits (90), Expect = 4e-05

		 Identities = 47/289 (16%), Positives = 90/289 (31%), Gaps = 30/289 (10%)

		

		Query: 9    LKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDE-AGRYSMDVEYGQYSVILLVEGF 67

		            + D TG+P  N      A +     +  ++     D  A +Y +    G+Y +      +

		Sbjct: 928  VADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDL------Y 981

		

		Query: 68   PPSHAGTITVYEDSQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEA 127

		             P         + +   T N+    +       E + R +         A  ++      

		Sbjct: 982  NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE----TT 1037

		

		Query: 128  ETSARNAGISSSKAEASAANADTSAGDALESARQAA-ESAAAAKQSEDASSSSASAAAQK 186

		            ET A N+   S   E +  +A  +     E A++A     A  + +E A S S +   Q 

		Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097

		

		Query: 187  ASESSQSAAEA------------ELSRKTAESAAGNAARDAT-TATEKARE-----SAES 228

		                  +  E             E+ + T++ +      +      E ARE     + + 

		Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157

		

		Query: 229  AQSAEQSRIAAEEAVNRIPTVVGPPGPKGEQGPAGPQGPKGDKGERGDT 277

		             QS   +    E+      + V  P  +      G    +  +     T

		Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  219 bits (560), Expect = 8e-69

		 Identities = 63/216 (29%), Positives = 115/216 (53%), Gaps = 3/216 (1%)

		

		Query: 343 LGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIKAVIRRDSEQA 402

		           L  G     + +       +  +M  ++++  L AQ+NPHF+FNALN I+A+I  D  +A

		Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193

		

		Query: 403 SQLVQYLSTFFRKNLKR-PSEFVTLADEIEHVNAYLQIEKARFQSRLQVNIAIPQELSQQ 461

		            +++  LS   R +L+   +  V+LADE+  V++YLQ+   +F+ RLQ    I   +   

		Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253

		

		Query: 462 QLPAFTLQPIVENAIKHGTSQLLDTGRVAISVRREGQHLMLEIEDNAGL-YQPVTNASGL 520

		           Q+P   +Q +VEN IKHG +QL   G++ +   ++   + LE+E+   L  +    ++G 

		Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313

		

		Query: 521 GMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLP 556

		           G+  V +RL+  +G +  I ++ +        + +P

		Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 71.4 bits (175), Expect = 1e-16

		 Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 12/177 (6%)

		

		Query: 2   IKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRIS 61

		             +L+ DD+   R  L   L  ++  ++    SNA      +     D++  D+ MP  +

		Sbjct: 4   ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61

		

		Query: 62  GLEMVGMLDPEHRPYI--VFLTAFD--EYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQ 117

		             +++  +  + RP +  + ++A +    AIKA E+ A+DYL KP D   L   + R   

		Sbjct: 62  AFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120

		

		Query: 118 ERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVT--SHEGKE 172

		           E  ++   L  ++Q  +  +   G S       + +A +      + +T  S  GKE

		Sbjct: 121 EPKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 27.3 bits (60), Expect = 0.028

		 Identities = 19/94 (20%), Positives = 31/94 (32%)

		

		Query: 36  LNGTEIAITYVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKL 95

		           +   + AITY  K  K  K  S  ++ F +          KT     AK    +    K 

		Sbjct: 671 VANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730

		

		Query: 96  TYTDTYAQENVTIDMEKVDFKALQGISGINVSAE 129

		             +   +   V +   +V+F     I   N+   

		Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score =  714 bits (1844), Expect = 0.0

		 Identities = 241/843 (28%), Positives = 395/843 (46%), Gaps = 35/843 (4%)

		

		Query: 2   LRMTPLASAI---VALLLGIEAHAAEETFDTHFMMGGMKGEQVTNLRL--DDNQPLPGQY 56

		            R+      +    A        +AE  F+  F+      + V +L    +  +  PG Y

		Sbjct: 21  HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78

		

		Query: 57  DIDIYVNKQWRGKYEIIVKDNPHET----CLTREIVKRLGIN-----SDNFARENQCLTF 107

		            +DIY+N  +    ++       E     CLTR  +  +G+N       N   ++ C+  

		Sbjct: 79  RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138

		

		Query: 108 EQLVQGGSYSWDIGIFRLDLAVPQAWVEELENGYVPPENWERGINAFYTSYYVSQYYSDY 167

		             ++   +   D+G  RL+L +PQA++     GY+PPE W+ GINA   +Y  S      

		Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198

		

		Query: 168 KASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTDNNP-----GEWKSNTLYLEHGFSQIL 222

		           +  GNS   Y+   SGLN+  W+L  + ++S   ++       +W+    +LE     + 

		Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258

		

		Query: 223 GTLRIGDMYTSADIFDSVRFTGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282

		             L +GD YT  DIFD + F G +L  D  MLP+S++ F P + GIA+  A VTI+QNG+

		Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318

		

		Query: 283 VVYQKEVPPGPFSISDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 342

		            +Y   VPPGPF+I+D+  AG   DL V++KEADGS   + VPY++VP + + G ++Y  

		Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378

		

		Query: 343 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGTMVANNYYAFTLGTGWNT-RIGAIS 400

		            AG      A ++   F Q+   +G     T+YGGT +A+ Y AF  G G N   +GA+S

		Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438

		

		Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFLSQTSTRFGLAAWRYSSRDYRTFNDYVWANNK 460

		           VD T+++S   +    DGQS +  YNK L+++ T   L  +RYS+  Y  F D  ++   

		Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498

		

		Query: 461 DNYRRDKNDVYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516

		                 ++ V  +     DYY   + ++      ++Q L     ++ LS   + YWG S 

		Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557

		

		Query: 517 SSKDYQLSYSNNWRRISYTLAASQAYDENHAE-EKRFNIFISIPFD--WGDDVTTPRRQI 573

		             + +Q   +  +  I++TL+ S   +      ++   + ++IPF      D  +  R  

		Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617

		

		Query: 574 YMSNSTTFDDQGFASNNTGLSGTVGNRDQFNYGINLSHQHQGN---ETTAGANLTWTAPA 630

		             S S + D  G  +N  G+ GT+   +  +Y +   +   G+    +T  A L +    

		Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677

		

		Query: 631 ATVNGSYSQSSTYRQVGASVSGGLVAWSGGVNLANRLSETFAVMHAPGIKDAYVNGQKYR 690

		              N  YS S   +Q+   VSGG++A + GV L   L++T  ++ APG KDA V  Q   

		Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737

		

		Query: 691 TTNCNGVVVYDGLTPYRENHLMMDVSQSDSETELRGNRKMTAPYRGAVVLVDFDTDQRKP 750

		            T+  G  V    T YREN + +D +      +L        P RGA+V  +F   +   

		Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796

		

		Query: 751 WFIKALRSDGQPLTFGYEVNDMHGHNIGVVGQGSQIFIRTNEIPPAVNVAIDKQQGLSCT 810

		             +  L  + +PL FG  V      + G+V    Q+++    +   V V   +++   C 

		Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856

		

		Query: 811 ITF 813

		             +

		Sbjct: 857 ANY 859

		

		

		>TYPE3OMGPROT#Type III secretion system outer membrane G protein

		          family signature.

		          Length = 607

		

		 Score = 27.9 bits (62), Expect = 0.008

		 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

		

		Query: 6  KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 46

		          ++L G LLL++S +WA            ++K E L   + DF

		Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 33.9 bits (77), Expect = 7e-04

		 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 2/92 (2%)

		

		Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214

		           A+G E K   I GA   IG    +   + GA  + A+D + EKL    S    +  ++  

		Sbjct: 3   AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61

		

		Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELA 246

		             A    S   +    ++  E   +   V +A

		Sbjct: 62  FPADVRDSAAIDEITARIEREMGPIDILVNVA 93

		

		

		>PF03309#Bvg accessory factor

		          Length = 271

		

		 Score = 26.7 bits (59), Expect = 0.012

		 Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 7/31 (22%)

		

		Query: 36  KLPVIEITDPQSVSGR-------AGEYWVYL 59

		            L  +E+T P+SV G+       AG  + + 

		Sbjct: 169 ALRRVELTRPRSVIGKNTVECMQAGAVFGFA 199

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 28.3 bits (63), Expect = 0.015

		 Identities = 11/72 (15%), Positives = 26/72 (36%)

		

		Query: 9   VEKQPAAMRRIIGKHLAVPRWQDTCDYYNQMMERERLTVCFHAQLKQRHATMRFEEMNDV 68

		           +      ++      L +  W D     ++   RER+        +++   +  E M   

		Sbjct: 703 IPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHF 762

		

		Query: 69  ERERLVCAIDEL 80

		           E+  ++  +D L

		Sbjct: 763 EKGVMLQTLDSL 774