>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 35.9 bits (83), Expect = 2e-04 Identities = 31/158 (19%), Positives = 58/158 (36%), Gaps = 12/158 (7%) Query: 31 VLDLDAFESNLRQMQAWADRHGV--ALRPHAKAHKCPEIARRQLALGARGICCQKVSEAL 88 LDL A + NL ++ A V ++ +A H I A + + EA+ Sbjct: 8 SLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN--LEEAI 65 Query: 89 PFVAAGI-DDVHISNEVVGAAKLALLAQLARAARVSVCVDDAGNLADISAAMARAQAQVE 147 G + + A L + R++ CV L + A R +A ++ Sbjct: 66 TLRERGWKGPILMLEGFFHAQDLEIYD----QHRLTTCVHSNWQLKALQNA--RLKAPLD 119 Query: 148 VLVELDVGQGRCGVPDAAAAVALARQAQALPGVTFGGL 185 + ++++ G R G + +Q +A+ V L Sbjct: 120 IYLKVNSGMNRLGFQPDRVL-TVWQQLRAMANVGEMTL 156
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (298), Expect = 2e-34 Identities = 70/252 (27%), Positives = 120/252 (47%), Gaps = 10/252 (3%) Query: 5 LKSKTALVTGAYSGLGRHFAGLLAGAGARVALCGRRTELGHEVAEAIRQQGGQACVVPMD 64 ++ K A +TGA G+G A LA GA +A E +V +++ + A P D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VTRPDSVQAAIDAAASELGPLDIVINNAGVALSEPALDISEQAWTGLIDVNLNGAWRVAQ 124 V ++ E+GP+DI++N AGV +S++ W VN G + ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 125 ASARHFRAQGRPGSIVNIASILGQRVASHVAPYAAAKAGLLHLTRALALEWARHGIRVNA 184 + +++ + R GSIV + S + +A YA++KA + T+ L LE A + IR N Sbjct: 126 SVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 185 LAPGYIATDLNREFFASPAGEALIKR---------VPQRRLGQPQDLDGPLLLLASDASA 235 ++PG TD+ +A G + + +P ++L +P D+ +L L S + Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 236 FMTGSVIDVDGG 247 +T + VDGG Sbjct: 245 HITMHNLCVDGG 256
>PERTACTIN#Pertactin signature. Length = 922 Score = 41.6 bits (97), Expect = 3e-05 Identities = 99/477 (20%), Positives = 154/477 (32%), Gaps = 79/477 (16%) Query: 350 SVQTSGEGSHGAY---AHDGGTIVLNGDSLSAGGNHAYGMYAKDPGSAIDATNVTVNTEG 406 S+ +GE HG + + G G ++ G A G+ ++P + + N +V + G Sbjct: 40 SIIKAGERQHGIHIKQSDGAGVRTATGTTIKVSGRQAQGVLLENPAAELRFQNGSVTSSG 99 Query: 407 LYGFGARAENGGAITLKGGSISTDNATGQGTQDGDGSRAYALSADGANSSISAQDGVVIS 466 G +T+K G + D+AT D AL G + S D + Sbjct: 100 QLFDEGVRRFLGTVTVKAGKLVADHATLANVSDTRDDDGIALYVAGEQAQASIADSTLQG 159 Query: 467 TKGQRA-YGAYAT--------NGGHI---------ELGGGSVTTQGFMAYGLYASGNGST 508 G R GA T G HI +L V + ASG + Sbjct: 160 AGGVRVERGANVTVQRSTIVDGGLHIGTLQPLQPEDLPPSRVVLGDTSVTAVPASGAPAA 219 Query: 509 VDANGVDITT------SGGVGDGVWAYQGGTVNLNGGSVTVNGEPNANSPHETANGLVAV 562 V G + T +GG GV A G V+L ++ P A G V Sbjct: 220 VFVFGANELTVDGGHITGGRAAGVAAMDGAIVHLQRATIRRGDAP--------AGGAVPG 271 Query: 563 GGTGSAAAGTINASDLSIVTRGANSAGAKAGATVDTDNTYGVINLERSTITVQGQAAVAA 622 G A G D + ++L +S + A A Sbjct: 272 GAVPGGA--------------VPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAPQLGA-AI 316 Query: 623 EINYGSTLTATDSTLVSEQGDGIVLNDNASVSLASTRVEAAGASLVSNLNAAGQTQNITV 682 G+ +T + +L + G+ I A R AS +S AG Sbjct: 317 RAGRGARVTVSGGSLSAPHGNVIETGGGA-------RRFPPPASPLSITLQAGAR----- 364 Query: 683 GSGSNLTQNNGTLLQVNRGQEGMDGIVNLTLAAGSSSSGDVVDLDGLDQDSGLRDGGGKT 742 G L V LTLA G+ GD+V + G Sbjct: 365 AQGRALLYRVLPE------------PVKLTLAGGAQGQGDIVATELPPIPGAS---SGPL 409 Query: 743 NFTVAQGASWIGIVRGINDLAAEDGGEIINVGGEPIAGNVTGGQDSTIVFQNGADIG 799 + +A A W G R ++ L+ ++ ++ G + D ++ FQ A+ G Sbjct: 410 DVALASQARWTGATRAVDSLSIDNATWVMT--DNSNVGALRLASDGSVDFQQPAEAG 464
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 488 bits (1258), Expect = e-177 Identities = 246/347 (70%), Positives = 291/347 (83%), Gaps = 1/347 (0%) Query: 1 MIGFMRSYFSTDLAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKIIQAVGHEA 60 M+ R FS DL+IDLGTANTLIYV+G+GIVL+EPSVVAIR + + K + AVGH+A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVA-AVGHDA 59 Query: 61 KQMLGRVPGNIEAIRPMKDGVIADFTVTEQMLKQFIRMVHPRNMLAPSPRIIVCVPCGST 120 KQMLGR PGNI AIRPMKDGVIADF VTE+ML+ FI+ VH + + PSPR++VCVP G+T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESALGAGASHVYLIEEPMAAAIGAGLAVSDASGSMVVDIGGGTTEVAVISLG 180 QVERRAIRESA GAGA V+LIEEPMAAAIGAGL VS+A+GSMVVDIGGGTTEVAVISL Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEPTAELIKKEIGSAFPGSEVREIEVKGR 240 G+VY SVR+GGD+FDEAI+NY+RRNYG LIGE TAE IK EIGSA+PG EVREIEV+GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTVSSNEILESLTDPLNQIVSAVKIALEQTPPELGADITDKGIALTGGGAL 300 NLAEGVPR FT++SNEILE+L +PL IVSAV +ALEQ PPEL +DI+++G+ LTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLQEETGLPVVVAEESLTCVVRGCGQALDQLERLGEIFLRD 347 LR+LDRLL EETG+PVVVAE+ LTCV RG G+AL+ ++ G + Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSE 346
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 43.9 bits (103), Expect = 5e-06 Identities = 94/459 (20%), Positives = 156/459 (33%), Gaps = 75/459 (16%) Query: 215 GASASVDRSRILTRGRDADGVSVK---HGGIAVVSKSSIQTSGRSADGISVSGE------ 265 A A + I+ G G+ ++ GG+ S ++I+ SGR A GI + Sbjct: 31 AAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGILLENPAAELQF 90 Query: 266 RSLVVGDSLKISTKGENSHGVDVEDGGTLLLSRGDVESKGKDGRGVAIDDGGRAVIVGSK 325 R+ V S ++S G V K G+ VA + + Sbjct: 91 RNGSVTSSGQLSDDGIRRFLGTVTV---------------KAGKLVA-----DHATLANV 130 Query: 326 VSASGDRGIALHVDDKDSQAIVIGSRLQSSGRSGQAVLIEDGADALIAGSTIVADGLGV- 384 D GIAL+V + +QA + S LQ +G V IE GA+ + S IV GL + Sbjct: 131 GDTWDDDGIALYVAGEQAQASIADSTLQGAG----GVQIERGANVTVQRSAIVDGGLHIG 186 Query: 385 QVQGKGSQLIGLDVDIDAESEARYRQSREPALGLRVEDQAKALLVGGSIQA--------- 435 +Q + + + ++ + + V ++ L GG I Sbjct: 187 ALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAM 246 Query: 436 -------------KGDQATGVSVGGSGSLVFAAG-----TDIRATGDDSTGMRVSRDARA 477 +GD G +V G A D G+ VS + Sbjct: 247 QGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVS-GSSV 305 Query: 478 ILVGSDIQGGGKGLDI--TKGGQAGTVGGTVTATDARGVALSVSGRDSVAATIGTNLTAD 535 L S ++ G I +G + GG+++A + +G A L+ Sbjct: 306 ELAQSIVEAPELGAAIRVGRGARVTVSGGSLSAPHG---NVIETGGARRFAPQAAPLSIT 362 Query: 536 GQDGVAVEVRDAGRAYLIDSSLNARAVGLRAEGKDA--SVVSVGSSITAGTEIVPVGRAY 593 Q G G+A L + L G DA +V+ GT I P+ A Sbjct: 363 LQAG----AHAQGKALLYRVLPEPVKLTL-TGGADAQGDIVATELPSIPGTSIGPLDVAL 417 Query: 594 SEPAVGV-ASDTGATVILIGGDVTALGDNSVAAQATSGD 631 + A A+ ++ + +++V A + D Sbjct: 418 ASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASD 456
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.3 bits (58), Expect = 0.020 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 2/36 (5%) Query: 10 QEFMLEAVRMVRGGQSMAAVAKILGISPKTLHNWVK 45 +L A+ RG Q AA +LG++ TL ++ Sbjct: 438 YPLILAALTATRGNQIKAA--DLLGLNRNTLRKKIR 471
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 25.7 bits (56), Expect = 0.025 Identities = 9/47 (19%), Positives = 18/47 (38%), Gaps = 4/47 (8%) Query: 21 GVSVEEVCRKVGVSQATFYAWKKKYAGVGVS----ELRRLRQLEDEN 63 S+ E+ + GV++ Y K + + + +LE E Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEY 77
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 36.4 bits (84), Expect = 6e-05 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 98 FAFGTWRLNAQQESVLRQFVPEILTIANDELGKNILKRVVIEGYTDKTGSYLTNLNLSLQ 157 F F L + ++ L Q ++ + + VV+ GYTD+ GS N LS + Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKD------GSVVVLGYTDRIGSDAYNQGLSER 276 Query: 158 RSQKV 162 R+Q V Sbjct: 277 RAQSV 281
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.3 bits (68), Expect = 0.028 Identities = 64/338 (18%), Positives = 124/338 (36%), Gaps = 52/338 (15%) Query: 288 LGEVIASSIDQSLKTPLDEIASSVKSASGDQSKAAIDMLNDVMVHFSQRLNDLFGGQISG 347 + + + I +L++ A+ + SA G +K A+ + + RL I Sbjct: 1 MTTITTAQIKSTLQSAKQSAANKLHSA-GQSTKDALKKAAEQTRNAGNRL-------ILL 52 Query: 348 INELNKETAQSMQDAVTALNTLLGKVEDSGKR--ATEEMALKMASSIQAMEERQASINAQ 405 I + K S+ D V + L +V+ K A + A + + ER +I Sbjct: 53 IPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTI--- 109 Query: 406 TQDFVDQIRKLVESSQSETQQKLQGTLESVGQQMT---TILETLNTSQAQVFAQNQAREQ 462 F Q+ KL++ Q + L G E++G + IL T + + E Sbjct: 110 ---FAPQLDKLLQKYQ-KAGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDEL 165 Query: 463 AMADRASHTVSQMSGSVEAAIQEISAASKAMTESVSALSSATSTSVEKMNAGAERLGIAA 522 ++ VS S +KA E ++ L ++ +N+ +++L Sbjct: 166 IKKQKSGGNVSS------------SELAKASIELINQLVDTVASLNNNVNSFSQQLNTLG 213 Query: 523 SSFANAGERVAEVITQTTSIGNKLTEVSSSLSTSSTSLHEALGDYRVQREALAHVLAEVR 582 S +N +GNKL + + L L + ++ +L+ + Sbjct: 214 SVLSNT--------KHLNGVGNKLQNLPN-LDNIGAGL-----------DTVSGILSAIS 253 Query: 583 EMIGLAGKEANITADALQRIEVSTTKLGLAQKAADEYL 620 L+ +A+ A +E++T LG K +Y+ Sbjct: 254 ASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYI 291
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 28.6 bits (64), Expect = 0.005 Identities = 5/26 (19%), Positives = 18/26 (69%) Query: 19 LSNLLAESVLDNAALKDQLVDGFVAD 44 + +L++E ++ + AL+++ + F+ + Sbjct: 72 IEDLISEVLVSSVALENKFISQFILE 97
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 29.1 bits (65), Expect = 0.031 Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Query: 335 VVLMGGCGAAMGVLFGAIATFWHFYLRLAPVIERFLQIFSGVFFVSEQLPEQLRIWILWS 394 + L G A++G++ A+A + +++ ++ + SG F +QLP + + Sbjct: 154 IALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFL 213 Query: 395 PFAHGMQLLRSAYFSAYTSQDA---SLGYFLTSLVFLMVLALAAERLAR 440 P +H + L+R + F + AL RL R Sbjct: 214 PLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRRLLR 262
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 75.4 bits (185), Expect = 7e-20 Identities = 44/153 (28%), Positives = 73/153 (47%), Gaps = 8/153 (5%) Query: 25 PKAVAI----DPQRYAGKWYEIARLPTPLQRRCVGDVTVEYTVAPQSALHIDNRCRT-KH 79 P++V + Y GKWYE+ARL +R + VT EY V + + NR + + Sbjct: 20 PESVKPVSDFELNNYLGKWYEVARLDHSFERG-LSQVTAEYRVRNDGGISVLNRGYSEEK 78 Query: 80 GDVAAMSGLAVPREQAAGAQYRAEFLQP-TPDYWIIGLDSE-YRWAVVGSPDRKTLWILS 137 G+ G A + + F P Y + LD E Y +A V P+ + LW+LS Sbjct: 79 GEWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDRENYSYAFVSGPNTEYLWLLS 138 Query: 138 RTPQLPASLLEQARQAARAQGYRLDELRYTPQR 170 RTP + +L++ + ++ +G+ + L Y Q+ Sbjct: 139 RTPTVERGILDKFIEMSKERGFDTNRLIYVQQQ 171
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 28.2 bits (63), Expect = 0.043 Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 149 VLITGESGLGKSELALELISRGHGLVADDAV 179 L+TG +G ++ L+ GH +V D + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL 33
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 30.4 bits (68), Expect = 0.032 Identities = 34/159 (21%), Positives = 55/159 (34%), Gaps = 16/159 (10%) Query: 598 AANGEIRNITGLFDETLNDGEKRLVTGA--FEETIDGDVTQTIKGGGTFTETIMANHIHD 655 A N + +I G E + G + + GD +++ + + + Sbjct: 391 AINEAMSDIFGTLVEFYANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSK--R 448 Query: 656 LTGTQDSTITGAVTHTVNGTFTQTVTEPLTVNADTSMTVNTPSWTVSGAKQAFWTGSFLR 715 TGTQD+ G V HT +G + L V+ + F+ Sbjct: 449 YTGTQDN---GGV-HTNSGIINKAAY--LLSQGGVHYGVSVTGIGRDKMGKIFYRALVYY 502 Query: 716 GTP------ARATVVLAAADLWGVRQQVYAGINSQWSTV 748 TP RA V AAADL+G Q + ++ V Sbjct: 503 LTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAV 541
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 130 bits (329), Expect = 4e-35 Identities = 77/401 (19%), Positives = 160/401 (39%), Gaps = 14/401 (3%) Query: 88 FMQMLDSTVVATALPVMAQALGSTAVRLNVAITSYLLAVAVFVPVSGWAADRYGARRVFM 147 F +L+ V+ +LP +A N T+++L ++ V G +D+ G +R+ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 148 AAIALFTLSSVACALSQNLTQ-LVLARIVQGIAGAMMVPVGRIILLRVVPKQDLLKAMSF 206 I + SV + + L++AR +QG A + +++ R +PK++ KA Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 207 LSIPALLGPVIGPPLGGFMVTYMSWHWIFLINIPIGILGIALVRRYVPEIREASTPRLDW 266 + +G +GP +GG + Y+ HW +L+ IP+ + + + D Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 267 LGFLLSAICLATLVSAFEALGHSLIPPLAVASLAATGLLCGALYVLHARRAAHPIIDLTL 326 G +L ++ + + L S +L ++V H R+ P +D L Sbjct: 202 KGIILMSVGIVFFM---------LFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 327 LREPTFAISVLGGNLCRFAVGAMPFLLAVQLQVGFGLTPFSAG-LITFASAAGALLMKFV 385 + F I VL G + V ++ ++ L+ G +I F ++ ++ Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 386 ATPIVQRFGFRRVLTVNAVLTGLFIVACAAFTATTPVWLLIGILLAGGFFRSLQFTGVNT 445 +V R G VL + + + + TT ++ I I+ G + T ++T Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK-TVIST 371 Query: 446 LTYADIPPERMSSASSFAAMAQQLGISLGVGVAAVTLNLSM 486 + + + + + S L G+ + L++ + Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 237 bits (607), Expect = 6e-80 Identities = 124/270 (45%), Positives = 157/270 (58%), Gaps = 1/270 (0%) Query: 5 FAVDPGWAIAMAALLGLVVGSWLSVPAHRLPRMMEREWLQQYQEFRPAASGPEPAASAYT 64 P ++ L L++GS+L+V HRLP M+EREW +Y+ + Y Sbjct: 8 AHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEP-PYN 66 Query: 65 LWRPGWHCPACAAPVRGWRRLPVLGWLLLRGRCGACGEAIGWRYPAVEVTAALLFALCAW 124 L P CP C P+ +P+L WL LRGRC C I RYP VE+ ALL A Sbjct: 67 LMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAM 126 Query: 125 RFGPTPIALCAMGLCAALLALAWIDLQTSLLPDAITLPLAWAGLLVNLGGALAPLPLAVL 184 P L A+ L L+AL +IDL LLPD +TLPL W GLL NL G L AV+ Sbjct: 127 TLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVI 186 Query: 185 GAVVGYVFLWLLFHMFRLLTGREGMGYGDFKLLAALGAWFGLAALPGLLLVASLAGVAGA 244 GA+ GY+ LW L+ F+LLTG+EGMGYGDFKLLAALGAW G ALP +LL++SL G Sbjct: 187 GAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMG 246 Query: 245 GILRLTGHARRGQPLPFGPYLALAGMVMLL 274 L L + + +P+PFGPYLA+AG + LL Sbjct: 247 IGLILLRNHHQSKPIPFGPYLAIAGWIALL 276
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 8e-07 Identities = 24/194 (12%), Positives = 53/194 (27%), Gaps = 37/194 (19%) Query: 8 TPTPRRKRRLAAIVLLLLAAAVAAWLLFKPGGSQQAATRGGRGFGGAATMNMPVPVRVAE 67 TP RR R +A ++ L A + Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFI-LSVLGQ------------------------------ 79 Query: 68 AGTQDINIVLRALGTVTAY-NTVTVRSRVDGELVRVAFAEGQRVKAGDLLAQIDPRPFEV 126 + IV A G +T + ++ + + + EG+ V+ GD+L ++ E Sbjct: 80 -----VEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA 134 Query: 127 ALAQAQGQQQQNQALLANARRDLQRYQTLFKQDSIARQQLDTQAALVRQYEGTQKIDQAA 186 + Q Q + + + + + + Q + + + Sbjct: 135 DTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194 Query: 187 VDNAKLQLSYTRIT 200 + Q + Sbjct: 195 FSTWQNQKYQKELN 208
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 844 bits (2181), Expect = 0.0 Identities = 289/1036 (27%), Positives = 506/1036 (48%), Gaps = 29/1036 (2%) Query: 4 SRLFILRPVATTLSMVAILIAGFIAYRLLPVSALPEVDYPTIQVVTLYPGASPDVMTSLV 63 + FI RP+ + + +++AG +A LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TSPLERQFGQMPGLNQMSSTS-SGGASVITLQFSLDLSLDVAEQEVQAAINAASNLLPSD 122 T +E+ + L MSSTS S G+ ITL F D+A+ +VQ + A+ LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 LPVPPIYNKVNPADAPVLTLAISS--PTMPLPQVRDLVDTRMAQKLSQVPGVGLVGVAGG 180 + I + + ++ S P + D V + + LS++ GVG V + G Sbjct: 122 VQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QRPAVRIQVNPRALAAAGMSLADLRTAVVGANVNQPKGNLDGP------ERSTTIDANDQ 234 Q A+RI ++ L ++ D+ + N G L G + + +I A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 235 LKSPTDYNDLII-AYRNNAPLRLSDVATAVQGAEDVRQAAWAGGQPAILLNVQRQPGANV 293 K+P ++ + + + + +RL DVA G E+ A G+PA L ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 IDVVDRIRAMLPQAQAALPATLDVSIVSDRTQTIRASVSDVQFEMMLAVALVVMVTFLFL 353 +D I+A L + Q P + V D T ++ S+ +V + A+ LV +V +LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 RSLTATFIPSVVVPLSLVGTFGIMYLAGFSINNLTLMALTIATGFVVDDAIVMIENIARH 413 +++ AT IP++ VP+ L+GTF I+ G+SIN LT+ + +A G +VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 L-EQGETPMQAALKGAAQIGFTLISLTFSLIAVLIPLLFMTEVVGRLFREFAITLAVAIL 472 + E P +A K +QI L+ + L AV IP+ F G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 ISLVVSLTLTPMMCARLLRPESEQRH---GRFHQATGAFIDRTIAHYDRMLQWVLAHQRL 529 +S++V+L LTP +CA LL+P S + H G F D ++ HY + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 530 TLLVALGTFVLTALLYIAIPKGFFPQQDTGMIQAITQAPASVSFPAMAQRQQEAARIVLQ 589 LL+ +L++ +P F P++D G+ + Q PA + + + L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 590 D--PDVESVSSFIGVDGTNATLNTGRMQIALKPHGERDGD---LAEVTRRLQQALDAQQG 644 + +VESV + G + N G ++LKP ER+GD V R + L + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 645 LKVYMQPVQDLTIEDRVSRTQYQMTL---SNPDIAVLAEWAPKLVERLSQLP-ELTDVAH 700 V P I + + T + L + L + +L+ +Q P L V Sbjct: 660 GFVI--PFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 701 DLQDDGLQTWVDIDRDAAARLGISTSAIDEALYNAFGQRLISTIFTQSNQYRVVLEVLPQ 760 + +D Q +++D++ A LG+S S I++ + A G ++ + ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 761 FRQSPEALGQIHLATESGTLVPLSAVAHISQGRTMLAINRLDQFPMTTVSFNLAPGASLS 820 FR PE + ++++ + +G +VP SA + R + P + APG S Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 821 AAVDAIAEAEAGIGMPASIETRYQGAALAFQNSLSSTLWLILAAVITMYIVLGVLYESYI 880 A+ + + +PA I + G + + S + L+ + + +++ L LYES+ Sbjct: 838 DAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 881 HPVTILSTLPSAAVGALLALMISGTELDMIGIIGIILLIGIVKKNAIMMIDFALEAERKR 940 PV+++ +P VG LLA + + D+ ++G++ IG+ KNAI++++FA + K Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 941 GLAPRAAIHEAALLRFRPILMTTLAALFGALPLMLSTGTGAELRQPLGLVMVGGLLLSQV 1000 G A A +R RPILMT+LA + G LPL +S G G+ + +G+ ++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1001 LTLFTTPVIYLMFDRL 1016 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 791 bits (2045), Expect = 0.0 Identities = 291/1032 (28%), Positives = 504/1032 (48%), Gaps = 28/1032 (2%) Query: 7 FIVRPVATVLLCLGLVLAGVLSFRLLPVAPLPEVDLPIISVTANLPGASPETMASSVATP 66 FI RP+ +L + L++AG L+ LPVA P + P +SV+AN PGA +T+ +V Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LERSLGSIAGVTEMTSR-NSQGSTRITLQFDLSRDIDGAARDVQAAINAARSLLPTGLRS 125 +E+++ I + M+S +S GS ITL F D D A VQ + A LLP ++ Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ- 123 Query: 126 NPTYHKVNPSSAPIMVLALTSDT--LSQGRLYDLASTIVAQKLAQVNGVGEVTVGGSSLP 183 SS+ +MV SD +Q + D ++ V L+++NGVG+V + G+ Sbjct: 124 QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY- 182 Query: 184 AVRVNLIPGALSSRGVSLDEVRATLTEANANRPKGVVENDRY------HWQIMASDQLER 237 A+R+ L L+ ++ +V L N G + + I+A + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 AEQYRPLVV-AWRDGAAVRLSDVATVEDSVEDLFQTGFYNNRQAILLILRRQADANIIET 296 E++ + + DG+ VRL DVA VE E+ N + A L ++ AN ++T Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 297 VEAIRAQLPQLAALLPGDVDMTVAQDRTPSIRASLHEAELTLVVAVALVMLVVLLFLRHW 356 +AI+A+L +L P + + D TP ++ S+HE TL A+ LV LV+ LFL++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 357 RAALIPSVAVPVSLVGTFCIMYLCGYTLNTISLMALIVATGFVVDDAIVVLENIMRHI-E 415 RA LIP++AVPV L+GTF I+ GY++NT+++ +++A G +VDDAIVV+EN+ R + E Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 416 QGASPMRAALRGSREVGFTVLSMSLSLVAVFIPILLMGGVVGRLFREFAVTLSAAIMVSL 475 P A + ++ ++ +++ L AVFIP+ GG G ++R+F++T+ +A+ +S+ Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 476 VVSLTLTPMMCARLLR--TQDHGRAPGRLSRAIGRGFDAVLARYRRSLSWALAHGRIMLL 533 +V+L LTP +CA LL+ + +H G FD + Y S+ L LL Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLL 542 Query: 534 LLAAAIGLNVYLYAVVPKGFFPQQDTGQLLGFFRVDQGTSFQATVPKLEYFRKVILSDP- 592 + A + V L+ +P F P++D G L ++ G + + T L+ L + Sbjct: 543 IYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602 Query: 593 ----AVASITVHAGGRGGSNSSFMSIQLKPQAERKASANDV---VNRLRGRLQNTPGARV 645 +V ++ + N+ + LKP ER N ++R + L V Sbjct: 603 ANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 646 FLVPQQDIFLGGGQGSGSYDYTLLAGELSL-LRTWMPKV-QQAMAALPELTDVDTSVEDK 703 I G ++ AG L ++ A L V + + Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 704 GRQVELVIDREAATRLGISMSDISAVLNNSFSQRQVSVMYGPLNQYHVVMGVVQRFAQDA 763 Q +L +D+E A LG+S+SDI+ ++ + V+ + + +F Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 764 ESLKQVHVITQDGRRVPLAAFAHFESGNAPLSVRHNGLLAADEISFNLAPGVSLDQAIRA 823 E + +++V + +G VP +AF + L + EI APG S A+ Sbjct: 783 EDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMAL 842 Query: 824 IDAAVARIGLPSDQIQAGFLGTAAAQQEVQSQQPWLILGALVTMYIVLGILYENLVHPLT 883 ++ ++ LP+ I + G + ++ +Q P L+ + V +++ L LYE+ P++ Sbjct: 843 MENLASK--LPAG-IGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 884 ILSTLPSAGIGALLALMLVGSEFTIIALIGVFLLIGIVKKNAIMMVDFALDAERRRGLSP 943 ++ +P +G LLA L + + ++G+ IG+ KNAI++V+FA D + G Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 944 RDAIFEACLTRFRPIMMTTLAAIFGALPLVLATGAGVEMRQPLGVTIVGGLILSQILTLY 1003 +A A R RPI+MT+LA I G LPL ++ GAG + +G+ ++GG++ + +L ++ Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1004 TTPVVYLYLDRF 1015 PV ++ + R Sbjct: 1020 FVPVFFVVIRRC 1031 Score = 91.8 bits (228), Expect = 8e-21 Identities = 75/502 (14%), Positives = 166/502 (33%), Gaps = 29/502 (5%) Query: 5 APFIVRPVATVLLCLGLVLAGVLSFRLLPVAPLPEVDLPIISVTANLPGASPETMASSVA 64 + +L+ +V V+ F LP + LPE D + LP + + V Sbjct: 531 GKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVL 590 Query: 65 TPLER-----------SLGSIAGVTEMTSRNSQGSTRITLQFDLSRDIDGAARDVQAAIN 113 + S+ ++ G + + G ++L+ + +G +A I+ Sbjct: 591 DQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLK--PWEERNGDENSAEAVIH 648 Query: 114 AARSLLPTGLRSNPTYHKVNPSSAPIMVLALTSDTLSQG-----RLYDLASTIVAQKLAQ 168 A+ L + + + Q L + ++ Sbjct: 649 RAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 169 VNGVGEVTVGGSS-LPAVRVNLIPGALSSRGVSLDEVRATLTEANANRPKGVVEND-RYH 226 + V G ++ + + GVSL ++ T++ A + R Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 227 WQIMASDQLER--AEQYRPLVVAWRDGAAVRLSDVATVEDSVEDLFQTGFYNNRQAILLI 284 + +D R E L V +G V S T + + + + Sbjct: 769 KLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWV----YGSPRLERYNGLPSM 824 Query: 285 LRRQADANIIETVEAIRAQLPQLAALLPGDVDMTVAQDRTPSIRASLHEAELTLVVAVAL 344 + A + +A A + LA+ LP + + R S ++A + ++ + Sbjct: 825 EIQGEAAPGTSSGDA-MALMENLASKLPAGIGYDWT-GMSYQERLSGNQAPALVAISFVV 882 Query: 345 VMLVVLLFLRHWRAALIPSVAVPVSLVGTFCIMYLCGYTLNTISLMALIVATGFVVDDAI 404 V L + W + + VP+ +VG L + ++ L+ G +AI Sbjct: 883 VFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAI 942 Query: 405 VVLENIM-RHIEQGASPMRAALRGSREVGFTVLSMSLSLVAVFIPILLMGGVVGRLFREF 463 +++E ++G + A L R +L SL+ + +P+ + G Sbjct: 943 LIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAV 1002 Query: 464 AVTLSAAIMVSLVVSLTLTPMM 485 + + ++ + ++++ P+ Sbjct: 1003 GIGVMGGMVSATLLAIFFVPVF 1024
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (257), Expect = 1e-28 Identities = 72/263 (27%), Positives = 118/263 (44%), Gaps = 18/263 (6%) Query: 8 LEGRHALVTGGARGIGLSCAQALLQRGAAVTLLGRDRAALDAAAAALGRLG-AVRAVAAD 66 +EG+ A +TG A+GIG + A+ L +GA + + + L+ ++L A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VADQASVQAAFEQAAQDGGAVDILVNNAGQAASQRFERTDAALWQAMLAVNLTGTYYCIQ 126 V D A++ + ++ G +DILVN AG W+A +VN TG + + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 AALPGMLAAGWGRIVNVASTAGLIGYAYVSAYCAAKHGVVGLTRALALEVARKGVTVNAV 186 + M+ G IV V S + ++AY ++K V T+ L LE+A + N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 CPGFTETDIVRGAVDNIMQKTGRTASEARAELAARN--------PQGRLVQPEEVAEAVA 238 PG TETD MQ + ++ + P +L +P ++A+AV Sbjct: 186 SPGSTETD---------MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 239 WLALPASASINGQAIAVDGGEVM 261 +L + I + VDGG + Sbjct: 237 FLVSGQAGHITMHNLCVDGGATL 259
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 27.8 bits (62), Expect = 0.001 Identities = 12/45 (26%), Positives = 19/45 (42%), Gaps = 4/45 (8%) Query: 10 GWVYDEEAGL-PDEGIAPGTRWEDVPP---NWVCPECGARKEDFE 50 G D G P EG+A GTR + P +++ + E+ Sbjct: 220 GKSIDTSMGFTPLEGLAMGTRSGSIDPSIISYLMEKENISAEEVV 264
>SECA#SecA protein signature. Length = 901 Score = 27.1 bits (60), Expect = 0.025 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 8/72 (11%) Query: 18 IAIGNTLTRQARPLEIIFSEIREARFARIGQLLQQWQPQRVVVGLALASDGGEQPATARC 77 I +G + + LE +E E A Q + V+ L G E+ + Sbjct: 513 IVLGGSWQAEVAALENPTAEQIEKIKADW-----QVRHDAVLEAGGLHIIGTERHES--- 564 Query: 78 RRFANQLRGRYG 89 RR NQLRGR G Sbjct: 565 RRIDNQLRGRSG 576
>PF07132#Harpin protein (HrpN) Length = 356 Score = 27.7 bits (61), Expect = 0.027 Identities = 26/87 (29%), Positives = 36/87 (41%) Query: 43 GGCANRSASSGVYSYDQAQREQIVRIGTVTGVRPITIQDDKSSGVGMIAGGALGGVAGNA 102 GG ++SA G S Q I+ G G+G GG GG+ G Sbjct: 32 GGSPSQSAFGGQRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGG 91 Query: 103 VGGGTGRALATVGGAILGALAGNAVEN 129 +GGG G +L + G+ LG G A+ Sbjct: 92 LGGGLGSSLGSGLGSALGGGLGGALGA 118
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.039 Identities = 34/288 (11%), Positives = 69/288 (23%), Gaps = 47/288 (16%) Query: 707 HLDALPLPPAHAPEQPYRMLVAGMGGTGVITIGAIVSVAAHLQGLSASVLDLTGLAQKGG 766 HL+ + P + P ++ + ++++ V + A G + Sbjct: 45 HLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIEN 104 Query: 767 TVVSHIRLAP-PHAPEGPV--RLDWQQADAAILCDPVAAVAPDSLGALRRGHTQVVVNTY 823 ++V I + +G V +L A+A L +++ L R + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTL-KTQSSLLQARLEQTRYQILSRSIELN 163 Query: 824 VAPVSEFTRNPDAALRPEALLAKIRHAAGEARTAALDAHQAALALFGDSILSNMFMLGYA 883 P + P E + ++ Q Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLI----KEQFSTWQNQKY---------------- 203 Query: 884 WQRGAVPLSHAALARAIELNGVAVQANRDAFEAGRLAAHQPQALE----DALRP--AAQV 937 ELN +A R A +E D Q Sbjct: 204 ---------------QKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 938 VQLHVPESFERAVARRERDLTAYQN--AAYARQYRELVDRVAQREREL 983 + H E +L Y++ + + + Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 64.8 bits (158), Expect = 1e-13 Identities = 76/321 (23%), Positives = 113/321 (35%), Gaps = 16/321 (4%) Query: 10 NRAIALLALAAFVSASAFRICDPMLPRLAADFGTSTGQAAATVTAFAVAYGLLQMFFGPV 69 NR + ++ + A + P+LP L D + A Y L+Q PV Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLRDL-VHSNDVTAHYGILLALYALMQFACAPV 62 Query: 70 G----DRYGKYRVVAVATFACAIGSMGAVLAPSLDVLVVCRALSGAAGAGIVPLSMAWIG 125 DR+G+ V+ V+ A+ AP L VL + R ++G GA ++ A+I Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIA 121 Query: 126 DNVPYEQRQATLARFLTGTILGMAAGQLAGGWFADTVGWRWAF---GALVAGYLIVGLLL 182 D ++R GM AG + GG F AL + G L Sbjct: 122 DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFL 180 Query: 183 WREVAQQAAASAARPAPGPRQGFAAQVRVVLGVPWARVVLATVFVEGLLVFGALAFAPAY 242 E + R A P F R + V ++A F+ L+ A + Sbjct: 181 LPESHKGERRPLRREALNPLASFRW-ARGMTVVAA---LMAVFFIMQLVGQVPAALWVIF 236 Query: 243 LHARFGLSLTAAGAVVAVY-ALGGLLYTLVAGPVLRRLGERGLAAAG-GLVLCSAFLIYL 300 RF T G +A + L L ++ GPV RLGER G L+ Sbjct: 237 GEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAF 296 Query: 301 LGPAWGWGLAASMLAGFGYYL 321 W +LA G + Sbjct: 297 ATRGWMAFPIMVLLASGGIGM 317
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 863 bits (2231), Expect = 0.0 Identities = 327/1033 (31%), Positives = 555/1033 (53%), Gaps = 33/1033 (3%) Query: 3 LSEICIKRPVFASVLSLIIVLVGLISYSRLTVREYPNIDEPIVSVNTIYKGASPEVIESQ 62 ++ I+RP+FA VL++I+++ G ++ +L V +YP I P VSV+ Y GA + ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTKPLEDQLAGIEGVNVMTSRS-RTERSQINIKFDLSRDPDAAAAEVRDKVSRARRYLPD 121 VT+ +E + GI+ + M+S S I + F DPD A +V++K+ A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 EIDEPIIGKVEADAYPIIYIAVES--GSLSAIQTSDYINRYIKTRLSVLPGAAEVRVYGE 179 E+ + I ++ + ++ S + SDY+ +K LS L G +V+++G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 RLPSMRIYVDRDKLAAYNLTVQDVETALASQNVEIPAGRI------ESRDREFSVVSSTD 233 + +MRI++D D L Y LT DV L QN +I AG++ + S+++ T Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 LQTPAQFAAIVV-ANVKGYPVRLGDVAKVEIGAADDRILSRFNGRPAINIGLTRQSTANP 292 + P +F + + N G VRL DVA+VE+G + +++R NG+PA +G+ + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 293 LDLSKAVRAEVAQLNETLPAGMKLNIAYDSSVFIERSIQSVFRTIGEAIVLVVLVIFFFL 352 LD +KA++A++A+L P GMK+ YD++ F++ SI V +T+ EAI+LV LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 353 RNLRASIIPIVTIPVSLIGACGLMYLFGFSVNTLTLLAMVLAIGLVVDDAIVVLENIFRH 412 +N+RA++IP + +PV L+G ++ FG+S+NTLT+ MVLAIGL+VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 413 I-EEGMPRRQAAFQGAKEIGFAVVAMTLTLVTVYAPLAFATGRTGRLFIEFALTLAGAVL 471 + E+ +P ++A + +I A+V + + L V+ P+AF G TG ++ +F++T+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 472 VSGFVALTLTPMMCSVLLR-----HEPRHNRWYNLVEGWLEALARGYRRALGLALRHRGV 526 +S VAL LTP +C+ LL+ H ++ + Y ++G L G Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 527 VVVVGLLVAGASGVLFSVVKSELAPIEDRGVIFGTVSAPEGATLNYTLESMLEIEHFYSQ 586 +++ L+ VLF + S P ED+GV + P GAT T + + ++ +Y + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 587 IPEAE------ANQVSVGYPTVSDATAILRLKPWEQRERK---QQEIARELQPKFAGLPG 637 +A N S + A + LKPWE+R + + + + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 638 VKAFPTNPP---SLGQSARSKPVEFVIMSQASYPELARMVNVFVDALRSYPG-LQNLDTD 693 P N P LG + E + + + L + N + +P L ++ + Sbjct: 660 GFVIPFNMPAIVELGTATGFDF-ELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 694 LRLNTPELRVQVDRDKMADVGAGVDVVGRTLESMLGGRQVTRFKDEGEQYDVIVQVLPRD 753 +T + +++VD++K +G + + +T+ + LGG V F D G + VQ + Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 754 RANPADISGIYVRTRDGSMVQLDNLLSVHESVSPQSLNHFNRLRAVKVEAAVAPGYALGE 813 R P D+ +YVR+ +G MV + H L +N L +++++ APG + G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 814 VLEHMHEVARQVLPHTVVTDLDGQAREFRDSSGSIYLVFAMALAFIYLVMAAQFESWRNP 873 + M +A + LP + D G + + R S + A++ ++L +AA +ESW P Sbjct: 839 AMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 874 FIIMLSVPLSMTGALLALWASGGTLSIYSQIGLITLVGLITKHGILIVEFANQLRD-QGR 932 +ML VPL + G LLA +Y +GL+T +GL K+ ILIVEFA L + +G+ Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 933 ELVDAVVEASVLRLRPILMTTGAMVLGTLPLAVSHGAGAESRQQIGWVLVGGLMLGTLLT 992 +V+A + A +RLRPILMT+ A +LG LPLA+S+GAG+ ++ +G ++GG++ TLL Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 993 LFVVPVAYTLIAT 1005 +F VPV + +I Sbjct: 1018 IFFVPVFFVVIRR 1030 Score = 77.2 bits (190), Expect = 2e-16 Identities = 64/369 (17%), Positives = 135/369 (36%), Gaps = 36/369 (9%) Query: 668 PELARMVN-VFVDALRSYPGLQNLDTDLRLNTPE--LRVQVDRDKMADVGAGVDVVGRTL 724 +++ V D L G+ D++L + +R+ +D D + V L Sbjct: 152 DDISDYVASNVKDTLSRLNGV----GDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQL 207 Query: 725 ES----MLGGRQVTRFKDEGEQYDVIVQVLPRDRANPADISGIYVRT-RDGSMVQLDNLL 779 + + G+ G+Q + + R NP + + +R DGS+V+L ++ Sbjct: 208 KVQNDQIAAGQLGGTPALPGQQLNASIIAQTR-FKNPEEFGKVTLRVNSDGSVVRLKDVA 266 Query: 780 SVHESVSPQ-SLNHFNRLRAVKVEAAVAPG---YALGEVLEHMHEVARQVLPHTVVTDLD 835 V + N A + +A G + ++ + P + Sbjct: 267 RVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGM----- 321 Query: 836 GQAREFRDSSGSI---------YLVFAMALAFIYLVMAAQFESWRNPFIIMLSVPLSMTG 886 + D++ + L A+ L F LVM ++ R I ++VP+ + G Sbjct: 322 -KVLYPYDTTPFVQLSIHEVVKTLFEAIMLVF--LVMYLFLQNMRATLIPTIAVPVVLLG 378 Query: 887 ALLALWASGGTLSIYSQIGLITLVGLITKHGILIVE-FANQLRDQGRELVDAVVEASVLR 945 L A G +++ + G++ +GL+ I++VE + + +A ++ Sbjct: 379 TFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQI 438 Query: 946 LRPILMTTGAMVLGTLPLAVSHGAGAESRQQIGWVLVGGLMLGTLLTLFVVPV-AYTLIA 1004 ++ + +P+A G+ +Q +V + L L+ L + P TL+ Sbjct: 439 QGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLK 498 Query: 1005 TVRRKPGHA 1013 V + Sbjct: 499 PVSAEHHEN 507
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 2e-04 Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 3/56 (5%) Query: 90 VHDCAVLPAAQGLGVAQALLQGGLEHARRRGLCHTSLVALR---PAVSYWERLGYR 142 + D AV + GV ALL +E A+ C L A ++ + + Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 2e-16 Identities = 37/178 (20%), Positives = 68/178 (38%), Gaps = 3/178 (1%) Query: 1 MADRGRPRSFD-RDTALQKAMDLFWEKGYASTSLADLTAAMGINAPSLYSAFGSKEQLFR 59 MA + + + + R L A+ LF ++G +STSL ++ A G+ ++Y F K LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 60 DAVALYGSREGGCTQAELLSAP-TVRAGIENMLLAAVRAGTQPGRPKGCLIVLGAPT-GT 117 + L S G P + + +L+ + + R + + ++ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 118 DEHAPVQKMLCDSRRHTQALILQRLREAVRHGELPAHTDLPALASYYATVLHGMAIQA 175 E A VQ+ + + I Q L+ + LPA A + G+ Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 1e-39 Identities = 88/253 (34%), Positives = 136/253 (53%), Gaps = 15/253 (5%) Query: 4 LQGKIAFVTGGSRGIGAAIARHLAARGADVAITYVSTPERAQELVAELRGAGRRAHAYAA 63 ++GKIAF+TG ++GIG A+AR LA++GA +A PE+ +++V+ L+ R A A+ A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 64 DAADHQQVRAAVEQAVRDLGGLDILVNNAGIFIAGGLDTLSHADFQRTLDVNVSAVFAAT 123 D D + + R++G +DILVN AG+ G + +LS +++ T VN + VF A+ Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 QAALPHLP--RGGRIINIGSCLAGRAGDAGLAAYSASKAAVAGLTKGAARDLGPRGITVN 181 ++ ++ R G I+ +GS AG +AAY++SKAA TK +L I N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAG-VPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 VVHPGPIDTDMNP---AQREGAAESAARLA--------LQRYGHVDDIAGMVGYLASPAA 230 +V PG +TDM A GA + L++ DIA V +L S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 231 GYVTGAEISVDGG 243 G++T + VDGG Sbjct: 244 GHITMHNLCVDGG 256
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 39.4 bits (92), Expect = 1e-05 Identities = 24/103 (23%), Positives = 36/103 (34%), Gaps = 13/103 (12%) Query: 155 AMIESRQGLWHADEIAAVEGIDMLLVGAGDL-----AADLGAAGPA-----VQAALRDAF 204 M+E A+ A + +D +G DL AAD + A+ Sbjct: 429 IMVEIPSTAVAANLFA--KEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLV 486 Query: 205 DTVIAACKRHGKAAGA-GGLAGQLDLLAEVVAAGVRYVSAGTD 246 D VI A GK G G +AG + ++ G+ S Sbjct: 487 DMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSAT 529
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.6 bits (87), Expect = 8e-05 Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 11/134 (8%) Query: 35 IAGPMLQSDLGLNLDALGWLTGIFAVLGVAGGIPAGVVIGSVGGRRALVGGLLATAVGAA 94 ++ P + +D + W+ F + G G + +G +R L+ G++ G+ Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 95 VGAAS-PVYGWLLASRVIEGAGFLFITVAGPAVLQ--RQDMVRADRRDLAFALWSCFMPA 151 +G + L+ +R I+GAG A PA++ + + R AF L + Sbjct: 95 IGFVGHSFFSLLIMARFIQGAG----AAAFPALVMVVVARYIPKENRGKAFGLIG----S 146 Query: 152 GMAIAMLVGPLLGG 165 +A+ VGP +GG Sbjct: 147 IVAMGEGVGPAIGG 160
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 89.6 bits (222), Expect = 2e-23 Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 11/126 (8%) Query: 101 KVNIPSNVSFDTDKAVLKPALLPVLDSVARALNQH--PELRAKVVGHTDSTGSAAHNQTL 158 + S+V F+ +KA LKP LD + L+ + V+G+TD GS A+NQ L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 159 SENRARSVTDYLGKQGVAPARMTIEGRAARDPIGDNATAEGR---------AANRRVEVY 209 SE RA+SV DYL +G+ +++ G +P+ N + A +RRVE+ Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333 Query: 210 LYAVKQ 215 + +K Sbjct: 334 VKGIKD 339
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.0 bits (67), Expect = 0.008 Identities = 13/60 (21%), Positives = 25/60 (41%) Query: 59 EQSEQLQSELNTANLDRQRLRTQLAEAVAQRDANQATRDQASADLEQARARIQALNQEFK 118 E +QL++E + DA++ + Q LE+A +++ AL + K Sbjct: 358 EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNK 417 Score = 28.9 bits (64), Expect = 0.017 Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 14/74 (18%) Query: 59 EQSEQLQSELNTANLDRQRLRTQLAEAVA--------------QRDANQATRDQASADLE 104 + L+ + N +RQ LR L + Q ++A+R DL+ Sbjct: 295 AEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 354 Query: 105 QARARIQALNQEFK 118 +R + L E + Sbjct: 355 ASREAKKQLEAEHQ 368
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.5 bits (66), Expect = 0.014 Identities = 22/81 (27%), Positives = 31/81 (38%), Gaps = 14/81 (17%) Query: 126 NAAEIAATPGVQRLAF--------GSLDYGLDLGLTTDSDGAGVVL------DHARVQVL 171 N E RLAF GS DYG + G+ D +G +L + Sbjct: 84 NTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLYDVEGWTDMLPEFGGDSYTYADNY 143 Query: 172 LRSRAAGLAPALDGVFPGVQD 192 + RA G+A + F G+ D Sbjct: 144 MTGRANGVATYRNTDFFGLVD 164
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 30.9 bits (69), Expect = 0.008 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 1/91 (1%) Query: 273 ADDARFASNASRLQHREALRDELAALLAGHDAAALAEQLLRQGVPAAAVQNVEDVLHHPH 332 AD+ + + +S ++ + D +LAG A +E L + +P ++ V V H+ Sbjct: 127 ADNNFYGAASSYFEYVDTYGDNAGRILAGALATYQSEYLAHRRIPPENIRRVTRVYHNGI 186 Query: 333 TRHRGMVLEHGNYRGVGSPIKLSRTPATLRR 363 T E+ N R V + + P T RR Sbjct: 187 TGET-TTTEYSNARYVSQQTRANPNPYTSRR 216
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.007 Identities = 12/42 (28%), Positives = 15/42 (35%) Query: 254 AAARPGTGAPAAPTRPPAPPAAAPAAQPAPQPAPQPAPATPR 295 P P P PP AP P+P P+P P + Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.8 bits (119), Expect = 1e-08 Identities = 66/321 (20%), Positives = 114/321 (35%), Gaps = 10/321 (3%) Query: 86 GGLVAVFAVIPMLMSVRAGQWIDRVGVRRPVTLGNGLVVTGTVLPFAF-QTQWALLVAAC 144 G L+A++A++ + G DR G RRPV L + A W L + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFG-RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI 104 Query: 145 SIGVGFMLHQVSTQDVLGHAEPQRRLRNFSWLSLAMAGSGFSGPLIAGLAIDHLGSRMAF 204 G+ V+ + + R R+F ++S +GP++ GL F Sbjct: 105 VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPF 163 Query: 205 GILA-LGPLVALAGLRRLQPALRAMDHAIEPTERQARRR-PVAELLKLPPLRRILMVNTI 262 A L L L G L + + + A + + + Sbjct: 164 FAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQ 223 Query: 263 LSGAWDTHLFVVPLFGV-AIGLSATTIGSILAAF-ALGTFLIRLVLPFIQTRVRSWTLIR 320 L G L+V +FG ATTIG LAAF L + ++ + R+ + Sbjct: 224 LVGQVPAALWV--IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM 281 Query: 321 TAMGITAADFLIYPLFAEVTTLIGLSFILGLALGCCQPSILSLLHQHTPHGRAAEAVGLR 380 M +++ FA + +L + G P++ ++L + R + G Sbjct: 282 LGMIADGTGYILL-AFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSL 340 Query: 381 MAFINASQVSLPLTFGALGAV 401 A + + + PL F A+ A Sbjct: 341 AALTSLTSIVGPLLFTAIYAA 361
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (298), Expect = 1e-34 Identities = 68/250 (27%), Positives = 109/250 (43%), Gaps = 18/250 (7%) Query: 6 ALITGASRGIGRAIAVRLIEDGYDVVNFSRGAPAALLAGETF---------VSVDLADAA 56 A ITGA++GIG A+A L G + + D+ D+A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 57 RTSQAVAELAAQREVL-YLVNNAGMIKVADIERVSGQAMQETLAVNLVAPLLLLQGLLPS 115 + A + + + LVN AG+++ I +S + + T +VN + + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 116 MRRRGHGRVVNIGSRAA-LGKPGRTAYGASKAGLAGMTRTWALELAASGITVNAVAPGPV 174 M R G +V +GS A + + AY +SKA T+ LELA I N V+PG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 175 ATELFNQSNPPDHPRTRELAAS-------IPVGRIGQPEDVAHAVAMLLDPRAGFITGQT 227 T++ ++ + + S IP+ ++ +P D+A AV L+ +AG IT Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHN 250 Query: 228 LYVCGGMTVG 237 L V GG T+G Sbjct: 251 LCVDGGATLG 260
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.6 bits (66), Expect = 0.012 Identities = 26/110 (23%), Positives = 31/110 (28%), Gaps = 5/110 (4%) Query: 103 PPARPAPAVETAPPNDAATPVPAVPAAALETGASATTGNAPAEPAPAEPAAPAAAPQPPA 162 P V P P P E +P E APA A Sbjct: 79 PEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTA 138 Query: 163 VPAPA----SALVITKPLRSGQRVY-ARHTDLVVIGMVSQGAEVIADGNV 207 A + S + L Q Y AR L + G V +V DG V Sbjct: 139 TAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRV 188
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.021 Identities = 17/107 (15%), Positives = 35/107 (32%), Gaps = 25/107 (23%) Query: 392 LLDNLIGNALHHGEPP------VDVSLRREGGMAMLDVADHGRGIAPERRSEALRPFARL 445 L+ L+ N + HG + + ++ G L+V + G + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST------- 311 Query: 446 DDARTRTGNVGLGLA-LAEAIARAHGGQLAL-LQADSGGLLVRITLP 490 G GL + E + +G + + L G + + +P Sbjct: 312 ----------GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (257), Expect = 1e-27 Identities = 52/148 (35%), Positives = 79/148 (53%), Gaps = 1/148 (0%) Query: 6 TKLLVVDDDPALRQLLADYLNRHGYDTLLAPDANDLAARIARYAPDLLVLDRMLPGGDGA 65 +LV DDD A+R +L L+R GYD + +A L IA DL+V D ++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DACRRLREQGEDIPVILLTARDEAVDRIIGLEAGADDYLGKPFDPRELLARIE-AVLRRK 124 D R+++ D+PV++++A++ + I E GA DYL KPFD EL+ I A+ K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 125 RGPSALTKDAPVSFGPFVFDPAMRQLLR 152 R PS L D+ AM+++ R Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYR 151
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 55.6 bits (134), Expect = 3e-10 Identities = 36/236 (15%), Positives = 62/236 (26%), Gaps = 42/236 (17%) Query: 268 GRLAYSSTVGVLNYTDMAARSGAIDYGVTAGSGTLRYGLTPELTLESQMQSAPDLSTRGL 327 G YS T G A TL +GL T+ Q A Sbjct: 372 GHTRYSITAGEYR------SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 328 GSTYSAGDLGTFQAGATQSSFD-----DINAWRYRFGYNVNLFE---SVSLAVTNEQIGA 379 G + G LG TQ++ + RF YN +L E ++ L + Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLV-GYRYSTS 484 Query: 380 GFGDLAQY-------------------------RNGVAAAPQMRNTLAAGVPIMGWGTLT 414 G+ + A +A + + L + TL Sbjct: 485 GYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLY 544 Query: 415 GTYSGLRQSGEPIEQR-FGLQHSMLIA-PSVRLAVGADRDVVTGDYEMRAGVTMPV 468 + S G F + + L+ ++ + + + + Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.018 Identities = 17/78 (21%), Positives = 32/78 (41%), Gaps = 4/78 (5%) Query: 158 LSMLHERWPDVPRIALTATATAATRVEIAQRLALDQARHFVASFDRPNIRYRIV-EKNEV 216 L + + PD+P + ++A T T ++ +++ A D FD + I E Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDY---LPKPFDLTELIGIIGRALAEP 122 Query: 217 RRQLLDLIRAEHEGDSGV 234 +R+ L +G V Sbjct: 123 KRRPSKLEDDSQDGMPLV 140
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 51.3 bits (123), Expect = 2e-09 Identities = 27/132 (20%), Positives = 47/132 (35%), Gaps = 24/132 (18%) Query: 1 MRILLIGGTGFLGRHMAARLAGHGHVLIV---------PTRQYGRGRDLQLL--PTLTLV 49 M+ L+ G GF+G H++ RL GH ++ + + R L+LL P Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR---LELLAQPGFQFH 57 Query: 50 EADVHDDAVLDRLLR--ECDAVINLAGILHGGRGQPYGAGFARVHVQLP----QRIAQAC 103 + D+ D + L + V Y + I + C Sbjct: 58 KIDLADREGMTDLFASGHFERVFISP----HRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 104 RRHGVRRLLHVS 115 R + ++ LL+ S Sbjct: 114 RHNKIQHLLYAS 125
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 68.5 bits (167), Expect = 4e-19 Identities = 29/74 (39%), Positives = 52/74 (70%) Query: 4 KDVLEDCVRASLERYFEDLGESEPHDMWDMVMRCVERPVLEVALQRSGGNQSRASEMLGI 63 + L D V+ +L+ YF L + +D++++V+ VE+P+L++ +Q + GNQ+RA+ M+GI Sbjct: 24 QKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGI 83 Query: 64 TRNTLRKKLQAHNI 77 R TLRKKL+ + + Sbjct: 84 NRGTLRKKLKKYGM 97
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 26.6 bits (59), Expect = 0.016 Identities = 11/55 (20%), Positives = 19/55 (34%) Query: 17 KSVGVAYLLWFFLGGVGGHRFYAGKTGSAIAIIALTIIGVLLSVVGVGFFLLFIV 71 K V ++ L+W + G G L I L V+ F++ + Sbjct: 146 KVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISI 200
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.8 bits (67), Expect = 0.033 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 4/50 (8%) Query: 319 ALAALSYGIVRVTRLLRTMRVAAWASLGPYLAIAAALAAIYLVGQDIWVW 368 +L GI LLR + GPYLAIA +A ++ G I W Sbjct: 239 SLVGAFMGIGL--ILLRNHHQSKPIPFGPYLAIAGWIALLW--GDSITRW 284
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 26.2 bits (57), Expect = 0.018 Identities = 12/36 (33%), Positives = 16/36 (44%) Query: 54 RREAQEVRNETAAMADDAIAAELADNWVRKPAGKGG 89 R EAQ V++ M + LA+ WV G G Sbjct: 51 REEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNG 86
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.033 Identities = 12/66 (18%), Positives = 25/66 (37%), Gaps = 3/66 (4%) Query: 203 IVIPVILAQLWRRALLSKGQAAFDRALERIGPL---SIAALLLTLVLLFAFQGEAIIRQP 259 I+I L + +A R+ P+ S+A +L L L + + + Sbjct: 942 ILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNA 1001 Query: 260 LVIAML 265 + I ++ Sbjct: 1002 VGIGVM 1007
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.040 Identities = 13/46 (28%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARRLAADGFPVRRSHITRMAD---AVR---------YLLPA 201 +Q EL L DG+ V ++ ++R V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 26.0 bits (57), Expect = 0.043 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 5/34 (14%) Query: 14 GRTFGRGWRAY--ARGERWAS---NWLVSKGVPA 42 G T G AY ER A ++L+SKG+PA Sbjct: 259 GYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPA 292
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 98.6 bits (245), Expect = 8e-27 Identities = 61/199 (30%), Positives = 86/199 (43%), Gaps = 16/199 (8%) Query: 3 VNNKVAVVTGAASGLGLATCKALAAAGARVVGFD------LDAKTVQAALAPDIRGLAVD 56 + K+A +TGAA G+G A + LA+ GA + D + A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 57 VANEADIKTGIDTVLELHGAIHIVVNCAGILGPCKTLSKGQMFPTELWERVIAVNLSGTF 116 V + A I + G I I+VN AG+L P S E WE +VN +G F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHS----LSDEEWEATFSVNSTGVF 121 Query: 117 NMIRHAALAMSRNEPDESGDRGVIVNTASGAAWQGQMGQAAYSASKAGVIGMTLPIARDL 176 N R + M G IV S A + AAY++SKA + T + +L Sbjct: 122 NASRSVSKYMMDRR------SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 177 AEHGIRMVAIAPGLFDTGM 195 AE+ IR ++PG +T M Sbjct: 176 AEYNIRCNIVSPGSTETDM 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (322), Expect = 3e-38 Identities = 80/259 (30%), Positives = 123/259 (47%), Gaps = 12/259 (4%) Query: 4 NLFSLHGKTALITGASSGIGQHVAGVFARAGATVVLAARRMDRIEAAVAALREQGHAAHG 63 N + GK A ITGA+ GIG+ VA A GA + +++E V++L+ + A Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 64 IYLDVTRTETIAAAFDRAEQQCGAPIDILYNNSGVIHVSPFVEQKEEEIARIFDTNLKGA 123 DV + I R E++ G PIDIL N +GV+ +EE F N G Sbjct: 62 FPADVRDSAAIDEITARIEREMG-PIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 124 MLVAQEAARRMLPQRAGAIVNIASVAGMRAGGWLASYAASKAALIHLTKVMALELAAKGI 183 ++ ++ M+ +R+G+IV + S +A+YA+SKAA + TK + LELA I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 184 RVNAICPGTIESDMHDALSDFQEGLLKR-----------TPLRRFGRQDDLDGVSLLLAS 232 R N + PG+ E+DM +L + G + PL++ + D+ L L S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 233 DAGRYIVGAAIPVDGGQAL 251 +I + VDGG L Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 83.9 bits (207), Expect = 5e-22 Identities = 46/203 (22%), Positives = 80/203 (39%), Gaps = 13/203 (6%) Query: 33 KSQDEQYQLKRQAVIAEASRAFGHRGYQNVSLDEIAKSLNVTKPALYHYFKSKQELLYEC 92 + ++ Q RQ ++ A R F +G + SL EIAK+ VT+ A+Y +FK K +L E Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 93 HNLSME-IGDMALEEAMTTGKNGLEKLEKFVSIYIRDFASE----LGASAVLHEYSGMTP 147 LS IG++ LE + L L + + + +E L + H+ Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF--V 120 Query: 148 KDRKQIMARRRQFDLRLRDLI----QEGIDDKTIAE-CNPKLAVFWFMGAITS-IPRWYR 201 + + +R L D I + I+ K + + A G I+ + W Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 202 LDGDLSGADIAQTFVHFLVKGIQ 224 A+ +V L++ Sbjct: 181 APQSFDLKKEARDYVAILLEMYL 203
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 4e-33 Identities = 75/258 (29%), Positives = 117/258 (45%), Gaps = 13/258 (5%) Query: 4 LEGKVAFITGGGAGIGCASALLFAQEGAQVVIAERDTAAGEQTAAIVEKSTGRPARFIHT 63 +EGK+AFITG GIG A A A +GA + + + E+ + K+ R A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS-SLKAEARHAEAFPA 64 Query: 64 DVTEPESLEAAVKRTVAEFGRFDVLYNNAGGSTVRDSRVTDAPVDEFWSKMKLDLFGTWL 123 DV + +++ R E G D+L N AG +R + +E+ + ++ G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAG--VLRPGLIHSLSDEEWEATFSVNSTGV-F 121 Query: 124 GCRYGIQAMMDAGNGGSVINSTSIFALIGTHGKDAYTAAKGAVSALTRSMAVEYAQYRIR 183 + M GS++ S A + AY ++K A T+ + +E A+Y IR Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 184 VNAVAPGATATERVLKLLKDDGVTSKSLDGQ---------LFGLVQPEDIAHAALYLASD 234 N V+PG+T T+ L D+ + + G L L +P DIA A L+L S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 235 ESRSTTGHILAVDGGLTI 252 ++ T H L VDGG T+ Sbjct: 242 QAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 2e-11 Identities = 28/159 (17%), Positives = 59/159 (37%), Gaps = 10/159 (6%) Query: 25 RRLQPEEREQQIVEKAIEHFTRNGFEG-STRELAKQIGVTQPLLYRYFSSKEALIERVYT 83 + + +E Q I++ A+ F++ G S E+AK GVT+ +Y +F K L ++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 84 EVFQWRREWEAQIKDRSVP-----LRDRLHAFYMDYSTVILREEWIRIFIFAGLTRDGIN 138 E E + + + LR+ L ++ + R + IF G Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIH-VLESTVTEERRRLLMEIIFHKCEFVG-E 122 Query: 139 NRYLTRLRTQVFLPVLAELRAEF--GVDEPRDRAEVDAE 175 + + + + L + ++ A++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR 161
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 5e-11 Identities = 23/150 (15%), Positives = 54/150 (36%), Gaps = 9/150 (6%) Query: 82 RVRLANDLAEAKASVATAKAQLAAAEREDKRYRGLADVVAPQELDVRRTAAETARAQYEQ 141 V N+L K+ + ++++ +A+ E + L +L Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKL-------RQTTDNIGL 313 Query: 142 AIASLDRARINLERAEVRSPVNGIITNFSLL-PGAYAIAGQPVMALV-DQDSFYVAGYFE 199 L + + + +R+PV+ + + G + +M +V + D+ V + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQ 373 Query: 200 ETKLSRMGVGMPATIHLMGESRSLKGHVEG 229 + + VG A I + + G++ G Sbjct: 374 NKDIGFINVGQNAIIKVEAFPYTRYGYLVG 403 Score = 54.1 bits (130), Expect = 2e-10 Identities = 24/163 (14%), Positives = 56/163 (34%), Gaps = 12/163 (7%) Query: 6 QSSRVLKIALTLALAVLGAFTLWHLYAYYTYSPQTRDGKVRAD--VVALAADVSGRVDEV 63 SR ++ + L + + T +GK+ + + V E+ Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFILSVLGQVE-IVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 64 RVRDNQVVKHGDVLFVIDRVRLANDLAEAKASVATAKAQLA--AAEREDKRYRGLADVVA 121 V++ + V+ GDVL + + D + ++S+ A+ + L ++ Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 122 PQELDVRRTAAE-------TARAQYEQAIASLDRARINLERAE 157 P E + + E + Q+ + +NL++ Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR 213
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 7e-28 Identities = 72/256 (28%), Positives = 113/256 (44%), Gaps = 10/256 (3%) Query: 7 LQGRVAMITGGAGGIGLDIAKTYGRLGARVVLASRNQDRLDHAAAQLSEEGIDVLAVRAD 66 ++G++A ITG A GIG +A+T GA + N ++L+ + L E A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VRNYDEVKAAVESAVTHFGALDILVNNAAGNFYCPTAELSPNGWRTVIDIDLNGTFYGCH 126 VR+ + G +DILVN A LS W ++ G F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 AAYKHLKQSPFGGCIISIVTMLGLSGWPGAAHAGAAKAGILSLSRTLAVEWGADNIRVNT 186 + K++ G I+++ + A ++KA + ++ L +E NIR N Sbjct: 126 SVSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 187 ISPGPIGDTEGVRRLYQETGREE------LERKKTA--LGRFGRKTDIANAATYLASDMA 238 +SPG +T+ L+ + E LE KT L + + +DIA+A +L S A Sbjct: 185 VSPGST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 239 AYITGENMIVDGGRWL 254 +IT N+ VDGG L Sbjct: 244 GHITMHNLCVDGGATL 259
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 27.9 bits (62), Expect = 0.040 Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 212 MSWLKTLSLWDMTKNVVDLPMGAFLGGAF 240 MS +K + M NVVDL +G +G AF Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAF 29
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 354 bits (911), Expect = e-119 Identities = 124/366 (33%), Positives = 191/366 (52%), Gaps = 29/366 (7%) Query: 217 SLSQEVTSLRSELAFYRREYSGAHPYPNELQQIVGDSDAIRQLKSDIVKVAPLNVPVLII 276 L++ + + LA +R S + +VG S A++++ + ++ ++ ++I Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Query: 277 GESGTGKELAARAIHELSPRSKKRMVFVNAAALPTSLVESELFGYEGGAFTGAGKAGRKG 336 GESGTGKEL ARA+H+ R V +N AA+P L+ESELFG+E GAFTGA + G Sbjct: 167 GESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA-QTRSTG 225 Query: 337 KFEMADSGSLFFDEIGDMPIEIQVKLLRILQDGVYERLGGNQVGHSDFRLICASNRNFQS 396 +FE A+ G+LF DEIGDMP++ Q +LLR+LQ G Y +GG SD R++ A+N++ + Sbjct: 226 RFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQ 285 Query: 397 MIRDGQFRLDLYYRISGVTIRMPSLRERLDDIPVLVQSILVSFADRHRASVKLVSPRVYD 456 I G FR DLYYR++ V +R+P LR+R +DIP LV+ + + VK + Sbjct: 286 SINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALE 344 Query: 457 FLREQPWPGNVRQLLHEVEKAAIFCDGPEISIENFRLTT--KIPAPGTAEIRPWEEQQTI 514 ++ PWPGNVR+L + V + I+ E +IP + +I Sbjct: 345 LMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSI 404 Query: 515 PAAI-------------------------ESLERNMVKEALLRHRGNKKKAAEELGISRA 549 A+ +E ++ AL RGN+ KAA+ LG++R Sbjct: 405 SQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRN 464 Query: 550 YLYKKL 555 L KK+ Sbjct: 465 TLRKKI 470
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 366 bits (942), Expect = e-123 Identities = 129/369 (34%), Positives = 210/369 (56%), Gaps = 19/369 (5%) Query: 210 MGDEIKRLQQEISFYQRSLPRLSGNMQGMEFIVGESDAIRKLKERIKKIARLDVSVLLVG 269 + + I + + ++ +R +L + Q +VG S A++++ + ++ + D+++++ G Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 270 ESGVGKDLVAHAIHQLSPRAARDMVLVNAAAIPGNLVEAELFGYEGGAFTGAEKRGRTGK 329 ESG GK+LVA A+H R V +N AAIP +L+E+ELFG+E GAFTGA + TG+ Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA-QTRSTGR 226 Query: 330 FEQADQTTLFLDEIGDMPLDIQVKVLRTLQDGTFQRVGSAAQRHSDFRLISATNRDFQRM 389 FEQA+ TLFLDEIGDMP+D Q ++LR LQ G + VG SD R+++ATN+D ++ Sbjct: 227 FEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQS 286 Query: 390 LATGDFRLDLFYRISAVTIRVPPLRERLEDVPLLAHTFLERFMQRHNVQGKHFGPGVMAY 449 + G FR DL+YR++ V +R+PPLR+R ED+P L F+++ + + K F + Sbjct: 287 INQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALEL 345 Query: 450 LQSLPWPGNVRQLQHTVERAAIFSEQDEISCEDC------EVPLEVDSGPGIQGITGTLR 503 +++ PWPGNVR+L++ V R QD I+ E E+P + + ++ Sbjct: 346 MKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSIS 405 Query: 504 E---------MNMPDDSLSPGKLPSVHQAKSRIELGMIREALQRFEGNKKKAAEYLGISR 554 + D+L P L + + +E +I AL GN+ KAA+ LG++R Sbjct: 406 QAVEENMRQYFASFGDALPPSGL--YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNR 463 Query: 555 SHLYKILSE 563 + L K + E Sbjct: 464 NTLRKKIRE 472
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.6 bits (193), Expect = 2e-19 Identities = 65/256 (25%), Positives = 112/256 (43%), Gaps = 14/256 (5%) Query: 4 ELIYVTGASRGIGAMIACQLARRGFEVGCLSRSGHRPQVENVPGEIAARW-HTVACDVTD 62 ++ ++TGA++GIG +A LA +G + + + + + + AR DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 GEALKDAMSKLRDDLGISVRGLVNNAGLHTEAPSVDLPMDEFRRLMDINAVSLLRACQIA 122 A+ + +++ ++G + LVN AG+ L +E+ +N+ + A + Sbjct: 69 SAAIDEITARIEREMG-PIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 YPMLKESGGGLIVNIGSFYDKLGVKRN--IAYCASKAAVGAITRCLAVEWARDGIQVIDV 180 + + G IV +GS + GV R AY +SKAA T+CL +E A I+ V Sbjct: 128 SKYMMDRRSGSIVTVGS--NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 181 APGYIETDLNR--------EAMQAGPLREYLEKRIPRKKPGEAGDVAVLVSSLFQPGMEF 232 +PG ETD+ E + IP KK + D+A V L Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 233 LTGETIYIDGAQSVSV 248 +T + +DG ++ V Sbjct: 246 ITMHNLCVDGGATLGV 261
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.3 bits (65), Expect = 0.049 Identities = 16/36 (44%), Positives = 24/36 (66%), Gaps = 5/36 (13%) Query: 180 VSDIYSEQLYIGGLLSTVWVSDYDDMMVALDQDDRE 215 +S ++QL +GG+LS D D M+VALD+ +RE Sbjct: 456 LSSAATKQLDMGGVLS-----DLDTMLVALDKAERE 486
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.3 bits (66), Expect = 0.036 Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 37 PGADVIDVGGKTVMPGLIDCHVHVIA 62 PG +VI GK V G +D H+H I Sbjct: 116 PGTEVIAGEGKIVTAGGMDSHIHFIC 141
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.8 bits (132), Expect = 3e-10 Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 4/155 (2%) Query: 19 KLLLMGGLGFAFEALDAGIIAFILPVLRTQWSLSSLEV---GFLASSTYIGFLIGALLAG 75 + L++ A +A+ G+I +LP L S+ G L + + A + G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 76 LLGDRFGRRGVMMWALAIFCVMSIANAMTHDWHLFFLFRMLAGIGMGAEGAIIAPFLAEF 135 L DRFGRR V++ +LA V A + ++ R++AGI GA GA+ ++A+ Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADI 123 Query: 136 VASRYRGRFTGSLAGFFSFGFVIAALLGYFIVPLS 170 R R G ++ F FG V +LG + S Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFS 158 Score = 38.3 bits (89), Expect = 6e-05 Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 5/142 (3%) Query: 51 LSSLEVGF-LASSTYIGFLIGALLAGLLGDRFGRRGVMMWALAI-FCVMSIANAMTHDWH 108 + +G LA+ + L A++ G + R G R +M + + T W Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 109 LFFLFRMLAGIGMGAEGAIIAPFLAEFVASRYRGRFTGSLAGFFSFGFVIAALLGYFIVP 168 F + +LA G+G + L+ V +G+ GSLA S ++ LL I Sbjct: 303 AFPIMVLLASGGIGMPA--LQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 169 LSDNGWR-WVLVISAVPVVVLL 189 S W W + A ++ L Sbjct: 361 ASITTWNGWAWIAGAALYLLCL 382
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 116 bits (291), Expect = 4e-33 Identities = 75/264 (28%), Positives = 124/264 (46%), Gaps = 21/264 (7%) Query: 31 LAGKVALVSGGGSSGPGWSIGKASCATLARHGAVVCVLDASLEAAQDALAAVQALGGQGL 90 + GK+A ++G IG+A TLA GA + +D + E + +++++A Sbjct: 6 IEGKIAFITGAAQG-----IGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 91 ALQADVADAVAMERAVQAVMDRYGRLDILQANAGIGKVGGPEDTALADWERIQKVNVDSL 150 A ADV D+ A++ + G +DIL AG+ + G + +WE VN + Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 151 LIASRLVLPIMSQQGGGAIVTVSSVAGLRYLGYPHL---AYNVTKAAVIHFARMIAQQYA 207 ASR V M + G+IVTV S G P AY +KAA + F + + + A Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPA----GVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 208 GQGIRANTVVPGLIDTPRVRNTVARMFSADDFEQARAARDRQ-----VPMGRMGTPWEVA 262 IR N V PG +T + +++ ++ + + +P+ ++ P ++A Sbjct: 177 EYNIRCNIVSPGSTETDMQWS----LWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIA 232 Query: 263 NAVAFLASDEASYITGTELVVDGG 286 +AV FL S +A +IT L VDGG Sbjct: 233 DAVLFLVSGQAGHITMHNLCVDGG 256
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.4 bits (86), Expect = 2e-04 Identities = 18/111 (16%), Positives = 29/111 (26%), Gaps = 14/111 (12%) Query: 291 SEKRWQVLTSEPAAAPPATPAVATL------PQTAPAQLSPPTPSTPPQRETPVAASESS 344 S K+ Q T +P A P A P T E PV S + Sbjct: 1130 SPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTV 1189 Query: 345 LQTKPSPMQPPASDDQPDDESQRSALLQEHI-------ISPAPTTDRLQSI 388 T S ++ P + + ++ + P + Sbjct: 1190 -NTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATT 1239
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 27.3 bits (60), Expect = 0.038 Identities = 15/52 (28%), Positives = 18/52 (34%), Gaps = 2/52 (3%) Query: 119 IKVDGVLKYKAEPKPAGSEQDAAEQSAAPAPAPQEVPVPEASEPVNEPADEA 170 I V V EP A Q E P P P+ +P P PV + Sbjct: 45 ISVTMVTPADLEPPQA--VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP 94
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 27.8 bits (62), Expect = 0.036 Identities = 11/49 (22%), Positives = 19/49 (38%) Query: 155 LDLLMEQSMLARLPMAYGLLEGHRLALDVPVLTKALGDLIRNGTLSATA 203 L + +Q+ + + H L LD P L + I N ++A Sbjct: 55 LRAIKDQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEY 103
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 4e-04 Identities = 15/63 (23%), Positives = 32/63 (50%), Gaps = 5/63 (7%) Query: 94 SGWCGW--VQSMVVSPSWRRMGIAESLMHELLQWFSLLGVTKVVLESTQV---AEAMYQK 148 S W G+ ++ + V+ +R+ G+ +L+H+ ++W ++LE+ + A Y K Sbjct: 84 SNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAK 143 Query: 149 LGF 151 F Sbjct: 144 HHF 146
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 49.9 bits (119), Expect = 9e-09 Identities = 79/375 (21%), Positives = 145/375 (38%), Gaps = 52/375 (13%) Query: 43 LPMIETAFSVPVAIAAQLVTAFTLAYGLGSPIFVALLPAHQQRAGLLFALGLFVLANAAS 102 LP I F+ P A + TAF L + +G+ ++ L + LLF + + + Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 103 ALS-TDFTVLMVFRAIAGIGAGVYLAMGIAASAALSPPDQRGKSIAVIMGGMASGTVLGV 161 + + F++L++ R I G GA + A+ + A P + RGK+ +I +A G +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 162 PLSLLLAEQLGWESALWLVTLLGAIAFVGLIARLPSLPTVQAIPLKAKIALLTDSHVVVI 221 + ++A + W S L L+ ++ I L+ L ++ I L++ V + Sbjct: 157 AIGGMIAHYIHW-SYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFM 215 Query: 222 LLVS----LLAAISSLGMYTFLAPLIAAAEPNSSP------------------------- 252 L + +S L F+ + +P P Sbjct: 216 LFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGF 275 Query: 253 -SVTPY-----------------LWVWGVGGVLGSFLIGPLVDRVKGPTLTLWI-MAILA 293 S+ PY ++ + ++ ++ G LVDR +GP L I + L+ Sbjct: 276 VSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDR-RGPLYVLNIGVTFLS 334 Query: 294 VALLLLPASLSTGPWLVMLPIAIWGAVGWALQVPQNNELIKAREQQGDGNLAVALNESAL 353 V+ L L T W + + I + + + + +QQ G LN ++ Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS- 393 Query: 354 YLGSALGAAMGGVLL 368 +L G A+ G LL Sbjct: 394 FLSEGTGIAIVGGLL 408
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 30/173 (17%), Positives = 69/173 (39%), Gaps = 5/173 (2%) Query: 13 SRERGRPREFDIHTALDRAILYFREHGYNGVSIADLSQALKLSAGSIYKAFHSKHGLFTA 72 +++ + I LD A+ F + G + S+ ++++A ++ G+IY F K LF+ Sbjct: 5 TKQEAQETRQHI---LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 73 ALDRYMALRGQQIAEITASAESG-REKLRRLLVFYAESSHAAEGRYGCLVVVGAVELSST 131 + + G+ E A LR +L+ ES+ E R + ++ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 132 DEAIAAKV-ASALSANERRLKAIIEQGQQDGSISRTAEPGTTAKLMLALLQGM 183 + A+ + + + R++ ++ + + A +M + G+ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 3e-05 Identities = 64/372 (17%), Positives = 119/372 (31%), Gaps = 45/372 (12%) Query: 47 ISAQLNLSEQASGLIVTLTQLGYGLGLLLVVPLGDLFENRRLAISILAVGAIGLLISGFA 106 I+ N ++ + T L + +G + L D +RL + + + G +I Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 107 GSVEPFL-AASFLVGLGSVTVQILVPYA-AHLAPDATRGRVVGNVMSGLMLGIMLARPVA 164 S L A F+ G G+ LV A P RG+ G + S + +G + + Sbjct: 100 HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159 Query: 165 SMITYFTSWRVVFFLSFIGMVLLAGVLRFALPTRPVVARLRY-HQMLASMA--------- 214 MI ++ W + + I ++ + +++ + +L S+ Sbjct: 160 GMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT 219 Query: 215 -------------------HLVRTT-----PALRRRALYHASMFGAFSLFWTTTPLLLAG 250 H+ + T P L + + + +F T + Sbjct: 220 SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMV 279 Query: 251 PQ-----FGLS--QKGIALFALAGVAGAIAAPIAGRIADRGWIRSATAAAMLLGIGAFAI 303 P LS + G + ++ I I G + DR + +F Sbjct: 280 PYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLT 339 Query: 304 TYIGDIGTSLSLAMFVIAGVVLDFAVSANLVLGQRVIFSLAPEIRGRLNGLYMTTFFCGG 363 TS + + ++ VL V+ V SL + G L T F Sbjct: 340 ASFLLETTSWFMTIIIVF--VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSE 397 Query: 364 AIGSALGGWLFA 375 G A+ G L + Sbjct: 398 GTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.001 Identities = 17/93 (18%), Positives = 30/93 (32%), Gaps = 8/93 (8%) Query: 37 ALSNLATKAGGSAQSTQVAALETRLAELGQQLEAQRQQPDTLTTAQFETERQAIEQRVSR 96 S+L K + V E + E +L + Q Q E+E + ++ Sbjct: 239 DFSSLLHK--QAIAKHAVLEQENKYVEAVNELRVYKSQ-----LEQIESEILSAKEEYQL 291 Query: 97 IEQALGERLTAESLSPLHSRIEQLESRLTKAAQ 129 + Q + + L I L L K + Sbjct: 292 VTQLF-KNEILDKLRQTTDNIGLLTLELAKNEE 323
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.5 bits (66), Expect = 0.013 Identities = 15/58 (25%), Positives = 21/58 (36%), Gaps = 4/58 (6%) Query: 94 DERRRYAELQVQVEARRVEKTLAYQRAYDAAWQRLHPGMQRVNLPGANIASGASATSS 151 D RR QV VEA E A W + GM + G I++ + + Sbjct: 341 DIRRP----QVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQ 394
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 25.0 bits (54), Expect = 0.024 Identities = 6/24 (25%), Positives = 14/24 (58%) Query: 40 VDVHRQEIYERIHPGSASHFSGKH 63 +D+H +++ R GS+ +G+ Sbjct: 367 LDIHYEDLIRRKTDGSSKFINGRE 390
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 33.3 bits (76), Expect = 0.002 Identities = 6/53 (11%), Positives = 20/53 (37%), Gaps = 4/53 (7%) Query: 84 TQKAENERLRQREGAIDRRIQSALETERNQLKNDREQVA----SERQQTQGLL 132 K +++RL+ + + + + + + + K + + + G L Sbjct: 289 YAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGEL 341
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.0 bits (171), Expect = 1e-16 Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 3/174 (1%) Query: 43 EERCKRILEAAERVFARVGYGAATMEEMAREAGMSKRTLYAFYADKRELFTAVIGDVEGF 102 +E + IL+ A R+F++ G + ++ E+A+ AG+++ +Y + DK +LF+ + E Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 103 SGKRPHVPAAAGRDALIVELHDRLLEMARFVLSERQIRITRLII-SEAENHPELAVDFWS 161 G+ A + L + L+ + ++E + R+ II + E E+AV + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 162 R--IVVRVQAYLVDGLKELQRADETLREYDANRLASTIFGAILSDLHLRTLFGQ 213 + + + + LK A + R A + G I + Q Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 33.4 bits (76), Expect = 0.004 Identities = 23/94 (24%), Positives = 32/94 (34%), Gaps = 6/94 (6%) Query: 486 GNRLKSHLDDGQFLARVEGDMFVLVVPDCDVHRAALVAAHLQRVAGAPIDISGFSLDPTV 545 G + + L R + VP VH L A G + GF L Sbjct: 62 GGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAV---GFELLDQE 118 Query: 546 SIGISQYPESSRDREDL---LRNAKSAMGQVKAS 576 GISQ+ E + L L +G VK++ Sbjct: 119 KFGISQFSEQVNYQRALEGELARTIETLGPVKSA 152
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.9 bits (67), Expect = 0.023 Identities = 20/102 (19%), Positives = 29/102 (28%), Gaps = 17/102 (16%) Query: 386 TSAAASPATSTAAEPPSTTSVTPTPVISPRSPVAQAVSNDGVDALLDLLGTPDIEPPPIE 445 TS A+P S T V P + P++ P +EP P Sbjct: 35 TSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPP--------------EPVVEPEPEP 80 Query: 446 APLNEPT---VPDQPLEPIDPEPTAPQSEIEAKDARTSPSGE 484 P+ EP P+P + + R E Sbjct: 81 EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 2e-23 Identities = 68/257 (26%), Positives = 107/257 (41%), Gaps = 9/257 (3%) Query: 3 KRFEGKVVIVTGAAQGIGRGVALRAAAEGGRVLFVD---RAEFVTEVAAEAPGGNTVGLI 59 K EGK+ +TGAAQGIG VA A++G + VD + +A + Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 60 ADLETYEGARSAMAFAAEKFGGIDILINGVGGAIRMRPYAEFEPEQIDAEIRRSLMPTLY 119 AD+ A + G IDIL+N V G +R E+ +A + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 120 ACHAVLPHLLARGGGTIVNVSSNA--TRGIRRVPYSTAKGGVNALTQSLAMEYAPYNIRV 177 A +V +++ R G+IV V SN Y+++K T+ L +E A YNIR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 178 VATAPGGTNAPPRRVPRNAAGDSQQEQAWMREAVQQVTESNFFKRYGSLDDQVGPILFMA 237 +PG T + + D + ++ +++ K+ D +LF+ Sbjct: 183 NIVSPGSTETD---MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 238 SDEAAYITGTVLPVAGG 254 S +A +IT L V GG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 27.1 bits (59), Expect = 0.035 Identities = 14/37 (37%), Positives = 15/37 (40%) Query: 18 REARHLDEREWEPWLDLYAPDAEYWMPAWDDDDQLTV 54 R R W WL + A A PAW DD TV Sbjct: 5 RAIRQTARTGWLTWLAILAVTAPVTSPAWADDPPATV 41
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.6 bits (121), Expect = 6e-09 Identities = 70/380 (18%), Positives = 128/380 (33%), Gaps = 65/380 (17%) Query: 53 LAPSIAENFGLEVGSFAPVFAAGLFGLMVGALLLGPIADKIGRRWLVIAATFTFGLFTFL 112 + + ++G+ + +A A +LG ++D+ GRR +++ + + + Sbjct: 37 HSNDVTAHYGILLALYA-------LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAI 89 Query: 113 TASASSINEFVILRFLTGLGLGGAMPNLTALATEYSPR----RYQGMIVAWLFAGIPIGA 168 A+A + I R + G+ G A + + R+ G + A G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGP 148 Query: 169 IVGGLLSSWLLPFAGWQAAFHVGGVLPMLLALVLVFTLPESLRFLILKQDNPRRVLAIAN 228 ++GGL+ + A F L L L F LPES + + P R A+ Sbjct: 149 VLGGLMGGF-----SPHAPFFAAAALNGLNFLTGCFLLPESHK----GERRPLRREAL-- 197 Query: 229 RIVPSGFPPEQQFSSPQKPVTGIPVRHLFTNGRWSGTLLLWIPYFMNLLIIYFI---ISW 285 P+ T L+ ++FI + Sbjct: 198 -----------------NPLASFRWARGMTVVAA-------------LMAVFFIMQLVGQ 227 Query: 286 LPAML-------RQSGMPITAGIEAATAFSFGGAIGCLGTGKLLQMFGARKVALIEFVAT 338 +PA L R T GI A + TG + G R+ ++ +A Sbjct: 228 VPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIAD 287 Query: 339 ILFILLLSTYSDAYWSVMLIAGFLGFTVQGAQAALNALVAGFYPTAIRSTGIGWALGIGR 398 +LL+ + W I L AL A+++ + G + Sbjct: 288 GTGYILLAFATR-GWMAFPIMVLLAS-GGIGMPALQAMLSRQVDEERQGQLQGSLAALTS 345 Query: 399 VGSIIGPLIGGLMLSMHWQT 418 + SI+GPL+ + + T Sbjct: 346 LTSIVGPLLFTAIYAASITT 365
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 26.3 bits (58), Expect = 0.041 Identities = 15/60 (25%), Positives = 25/60 (41%), Gaps = 4/60 (6%) Query: 8 DILIVTKLDRHGRDAI-DISTTVRTLAEMGVRVYCLALGGADLTSSAGTMTMNVLNAVAQ 66 D+LI+ L++ G I + E V + ++LGG + + V AVA Sbjct: 111 DLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPE---DVPELHEAVKKAVAS 167
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.1 bits (179), Expect = 3e-18 Identities = 33/160 (20%), Positives = 59/160 (36%), Gaps = 2/160 (1%) Query: 12 AVIDAAMDVFWTNGFEASSTQELCERTGLGRGSLYHAFGSKQNLYEQALRRYQE-LGLKA 70 ++D A+ +F G ++S E+ + G+ RG++Y F K +L+ + + +G Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELE 74 Query: 71 QTEILNGPGTAKERLQALLQWGVDGDLDPEKRRSCMA-LFSVMERGSKDPVIDQINRAYV 129 PG L+ +L ++ + E+RR M +F E + V+ Q R Sbjct: 75 LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLC 134 Query: 130 NRLEAVICHVIAVGQRNGELADDRPALEVARAFLASYYGL 169 I + L D A GL Sbjct: 135 LESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 82/368 (22%), Positives = 130/368 (35%), Gaps = 36/368 (9%) Query: 37 VTQIGYLISLYAIGMVVGGPLLTVGLLKLRVPNKQALLWLLGFYAVAQSVAASATSYDIM 96 G L++LYA+ P+L G L R + LL L AV ++ A+A ++ Sbjct: 42 TAHYGILLALYALMQFACAPVL--GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVL 99 Query: 97 AAARVATGVAGSACFGVSLAICAEIVGAESR----GRAASIVVGGLMLATVLGVPIATII 152 R+ G+ G A V+ A A+I + R G ++ G++ VLG + Sbjct: 100 YIGRIVAGITG-ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF- 157 Query: 153 DQHWGWRASFWLVVALAVLCATVITFLVPRSKAAGTVSLGAELAEFKNRHLWAAYATSGL 212 A F+ AL L FL+P S L E WA T Sbjct: 158 ----SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVA 213 Query: 213 IIGATFAAFSYFAPILTEV--------TGFAAASIPWLLGVYGAANVVGNMVVGRYADKH 264 + A F + + + A +I L +G + + ++ Sbjct: 214 ALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAAR 273 Query: 265 --TMPIMVWGLIVLGAALAVFSIFAQNQVLSLGALIVIGLVGV--PMNPAMIARVMKTAH 320 ++ G+I G + FA ++ ++++ G+ P AM++R + Sbjct: 274 LGERRALMLGMIADGTGY-ILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEER 332 Query: 321 PGAL--VNTVHTSVINIGLGVGAWVGGLGIAAGYGNRSPLWVGVALAVLGLLSL--LPYL 376 G L TS+ +I VG L A Y W G A L L LP L Sbjct: 333 QGQLQGSLAALTSLTSI-------VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPAL 385 Query: 377 GRKAASRA 384 R S A Sbjct: 386 RRGLWSGA 393
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 33.3 bits (76), Expect = 9e-04 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 12/46 (26%) Query: 168 SQSELARRLAADGYPVQQSHISRMVD---AVR---------YLLPA 201 +Q EL L DGY V Q+ +SR + V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.028 Identities = 18/115 (15%), Positives = 43/115 (37%), Gaps = 4/115 (3%) Query: 36 QTMNDQADQEQLASRLQRLEAQAAGLAETIEAIQQRPAV-ATAADLKDTRQILEARAAQV 94 +T+ + + QE +A A + + V A + + E + Q Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 95 EKTLSSYAAADDLQALRVEVEQIK--ARQTAAPAPRAAAPARPRASGKAAAKPEP 147 +T + + +A +VE E+ + + T+ +P+ + + A + +P Sbjct: 1098 TETKETATVEKEEKA-KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151
>PF02370#M protein repeat Length = 168 Score = 30.8 bits (69), Expect = 0.007 Identities = 20/118 (16%), Positives = 39/118 (33%), Gaps = 9/118 (7%) Query: 30 SSSAPPAADAGAKLTPEEMKALGIEGDTPRDTVATLVAQVKQLRTELQTVLSDNKSQREE 89 SS + + KL E L E + + + R ++ E Sbjct: 2 SSISNVNTSSNGKLI-TEYNKLVEENSKLQKQLEEYLDSSDSKRENDP----QYRALMGE 56 Query: 90 NQRLRQRENSIDQRINSAL----ESERSNLRRDQQQAASERQQTEGLLADLQRRLESI 143 NQ LR+RE +I E + RR++ + + + + Q+ + + Sbjct: 57 NQDLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQL 114
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 121 bits (305), Expect = 1e-35 Identities = 80/259 (30%), Positives = 124/259 (47%), Gaps = 10/259 (3%) Query: 3 KRLENKVAFITGAAGGQGRAAAVVFAREGAKVAVVDVDEKGIEETARLVKETGGEAIAIR 62 K +E K+AFITGAA G G A A A +GA +A VD + + +E+ +K A A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVSNEEQVKGAIQKTVDTFGKLTTLYNNAGIAHKNFMILAHELSVEEWEKIQNVNTKGM 122 DV + + + G + L N AG+ L H LS EEWE +VN+ G+ Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLR---PGLIHSLSDEEWEATFSVNSTGV 120 Query: 123 FLVVKYGIPELLKAGGGTIINTSSTAGLINSPGGPSYTASKGAIISFTRHLAATYAKKGI 182 F + ++ G+I+ S + +Y +SK A + FT+ L A+ I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 183 RANAIAPGYVITLMTKAM---EDLLPEVDKVASE----ATPLGRGAQPEEIANVALFLAS 235 R N ++PG T M ++ E+ +V K + E PL + A+P +IA+ LFL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 236 DESSFVTGAVIVADGGMTI 254 ++ +T + DGG T+ Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.9 bits (64), Expect = 0.043 Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 380 AASQPATVETAQPGAGVPGVAAPGNAATPTPEPEARP 416 + P+ E P G PG A P N A P PEP P Sbjct: 43 GPTVPSPDEPGLPLPG-PGPALPTNGAIPIPEPGTAP 78
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.9 bits (64), Expect = 0.042 Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 380 AASQPATVETAQPGAGVPGVAAPGNAATPTPEPEARP 416 + P+ E P G PG A P N A P PEP P Sbjct: 43 GPTVPSPDEPGLPLPG-PGPALPTNGAIPIPEPGTAP 78
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.010 Identities = 25/115 (21%), Positives = 46/115 (40%), Gaps = 6/115 (5%) Query: 8 VDQAPESNEPAPAVPA-----TVEALQAELAAVRAELEAAQATVAGQQEQVLRARADAEN 62 VD+AP PAPA P+ E + E V + A T A +E A+++ + Sbjct: 1020 VDEAPVP-PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKA 1078 Query: 63 VRRRAQEDVSKARKFGIESFAESLVPVKDSLEAALAQPDQTLEALREGVEVTLKQ 117 + + S + ++ + E A + ++T E + +V+ KQ Sbjct: 1079 NTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQ 1133
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 141 bits (356), Expect = 4e-39 Identities = 86/396 (21%), Positives = 142/396 (35%), Gaps = 93/396 (23%) Query: 2 SKIIGIDLGTTNSCVAVMDGGQVKIIENAEGART----TPSIVAYMDDGETLVGAPAKRQ 57 S + IDLGT N+ + V G V + R +P VA VG AK+ Sbjct: 10 SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVA-------AVGHDAKQM 62 Query: 58 AVTNPKNTLYAVKRLIGRKFDEKAVQKDIDLMPYSIVKADNGDAWVEARGKKIAPPQVSA 117 P N + A++ + + IA V+ Sbjct: 63 LGRTPGN-IAAIRPM---------------------------------KDGVIADFFVTE 88 Query: 118 DVLRK-MKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAA 176 +L+ +K+ + ++ VP +R+A +++ + AG +I EP AAA Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAA 148 Query: 177 LAFGLDKSEKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQR 236 + GL SE V D+GGGT +V++I + V + +GG+ FD+ Sbjct: 149 IGAGLPVSE--ATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEA 197 Query: 237 IIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSS----QQTEINLPYITADAS 292 II+Y+ + G + AE+ K E+ S+ + EI + Sbjct: 198 IINYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEG 244 Query: 293 GPKHLNLKITRAKLEALVEEL----------IERTIDPCRVAIKDAGVKVSEIDDVILVG 342 P+ L + LEAL E L +E+ I + G ++L G Sbjct: 245 VPRGFTLN-SNEILEALQEPLTGIVSAVMVALEQCPPELASDISERG--------MVLTG 295 Query: 343 GMTRMPKVQEKVKEFFGKDPRKDVNPDEAVAAGAAI 378 G + + + E G +P VA G Sbjct: 296 GGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 9e-06 Identities = 13/60 (21%), Positives = 25/60 (41%) Query: 92 NKYTVEHSVYIDARFRGRGLAEALMRTLIARARERQLHVLVGGIDAANTASIRLHEKLGF 151 N Y + + + +R +G+ AL+ I A+E L+ N ++ + K F Sbjct: 87 NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.031 Identities = 22/102 (21%), Positives = 33/102 (32%), Gaps = 8/102 (7%) Query: 15 ALGKAENWAKD-ERRVCARLTKPCDCTIIVAEPCQPIARTAPRAPLLPPPMPAAQSPAAP 73 A K E+ L KP D T ++ I R P + P Sbjct: 83 AQNTFMTAIKASEKGAYDYLPKPFDLTELIGI----IGRALAEPKRRPSKLEDDSQDGMP 138 Query: 74 RFDGTERYVATDDLKLAVNAALTLQRPLLIKGEPGTGKTMLA 115 + + ++ T L+I GE GTGK ++A Sbjct: 139 LVGRSAAM--QEIYRVLARLMQT-DLTLMITGESGTGKELVA 177
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 7e-06 Identities = 77/389 (19%), Positives = 147/389 (37%), Gaps = 20/389 (5%) Query: 12 KIAVPAFGPSILYGISNGAILPVVALSARELDAS---VATSGLIVALIGIGSLVSNIPAA 68 + + L + G I+PV+ R+L S A G+++AL + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 69 MITSRYGERLSMMGAAALSVLALLLCIFAGHAAVLAVGVFLIGMASSVFMLARQTYMIDA 128 ++ R+G R ++ + A + + + A VL +G + G+ + +A Y+ D Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADI 123 Query: 129 VPAYMRARALSTLAGTMRIGVFVGPFAGAALIHFMGLQGAYWVAAVAMAGAGLIAHLAPD 188 RAR ++ G+ GP G + F + AA+ L P+ Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 189 MTPPERRDAAVQAKPRV----LDVARTHRRVFLTLGLGILLVSAVRASRQVVIPLWADHL 244 ERR +A + T + + + LV V A+ V+ D Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 245 GINPTTTSI---IYGLVAAIDMSVFYPAGTLMDRRGRLWVAVPSTLLMGFALIGTSLTSG 301 + TT I +G++ ++ ++ G + R G + + G I + + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMI--TGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 302 VIGFLIVSMMLGMGNGIGSGIVMTLGADAAPSTGRTEFLGIWRLVSDLGSSLGPVVLSAI 361 + ++L G GIG + + + + + G ++ L S +GP++ +AI Sbjct: 300 GWMAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358 Query: 362 TALVSLAAAVAAMGTFGLAGAAVFWRWLP 390 A A+ G +AGAA++ LP Sbjct: 359 YA----ASITTWNGWAWIAGAALYLLCLP 383
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.3 bits (164), Expect = 1e-15 Identities = 40/170 (23%), Positives = 66/170 (38%), Gaps = 7/170 (4%) Query: 85 QRLTALRRQLILDAAQRVFERDGLEKTTVRAIAKEAGCTTGAIYPWFGGKEAIYAELLEA 144 ++ RQ ILD A R+F + G+ T++ IAK AG T GAIY F K +++E+ E Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 145 SLERLRDRLASALAQGGG---GAARRVIEAFFGYYAERATEFSLGMYLFQ---GLGPRGL 198 S + + A+ G R ++ L +F +G + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 199 GREADDRLNARLRG-CVDLLGRGLRAAKPWPDEMVAVEQMQVFTYLMGLL 247 ++A L L + A D M + + Y+ GL+ Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 96.8 bits (241), Expect = 1e-24 Identities = 82/385 (21%), Positives = 138/385 (35%), Gaps = 59/385 (15%) Query: 1 MKKTLLAAALLAGFAGVAQAETSVTLYGIIDTGIGYNKVKGAGFDGSRVGMING--VQNG 58 MKK+L+A L A A VTLYG I G+ ++ + V G Sbjct: 1 MKKSLIALTLAAL---PVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 59 SRWGLRGTEDLGDGLQAVFQLESGFNSGNGNHAQDGRLFGRQATIGLQSDSWGRLDFGRQ 118 S+ G +G EDLG+GL+A++Q+E + + RQ+ IGL+ +G+L GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGW----GNRQSFIGLKGG-FGKLRVGRL 112 Query: 119 TNIASKYFGSIDPFGAG---FGQANIGMGLSAMNTVRWDNMVMYQTPSYSGFQFGVGYSF 175 ++ G I+P+ + G I + + +VR+D+ P ++G V Y+ Sbjct: 113 NSVLKDT-GDINPWDSKSDYLGVNKIAEPEARLISVRYDS------PEFAGLSGSVQYAL 165 Query: 176 SVDDNTTDDDRVGFRTADNVRGITTGLRYVNGPLNVALSYDQLNASNAQAQDEVDATPRS 235 + + N G Y NG V Q ++ + Sbjct: 166 NDNAG-----------RHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIE-KYQI 213 Query: 236 YGIGASYDFEVVKVALAYARTTDGWFGGQGINGIGAVDSDADGVDDQFPLSSNRFADGFK 295 + + + YD + + ++ + D + + V + RF + Sbjct: 214 HRLVSGYDNDALYASV-AVQQQDAKLVEEN-----YSHNSQTEVAATL---AYRFGNVTP 264 Query: 296 SNSYMVGLTAPIGGASKLFGSWQMVDPSNDKLTGGEEKMNVFSLGYTYDLSKRTNLYAYG 355 SY G + +G YD SKRT+ Sbjct: 265 RVSYAHGFKGSFDAT------------------NYNNDYDQVVVGAEYDFSKRTSALVSA 306 Query: 356 SYAKNYAFIDDVKSTAVGVGIRHRF 380 + + STA GVG+RH+F Sbjct: 307 GWLQEGKGESKFVSTAGGVGLRHKF 331
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.0 bits (59), Expect = 0.014 Identities = 11/49 (22%), Positives = 20/49 (40%) Query: 59 WGWRYGTVEWIGILTLAGLLLIWLVSFRAGPALAVGGVCAVAAPVLAWI 107 W + T+E ++ L S AG L + G+ V + ++I Sbjct: 460 WKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYI 508
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 114 bits (287), Expect = 7e-30 Identities = 75/412 (18%), Positives = 160/412 (38%), Gaps = 15/412 (3%) Query: 17 RQRQALAALCLAVLVAQVDTAAVNLATRAVGLHFHAGVQALQWVIDSYNLAYAALLLTGG 76 R Q L LC+ + ++ +N++ + F+ + WV ++ L ++ G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 77 LLADLWGRRRVFLLGAGLFCAASLGCALAPSVAA-LVAARVGAGVGAALLIPASLALIRV 135 L+D G +R+ L G + C S+ + S + L+ AR G GAA PA + ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVVVA 129 Query: 136 GWPDPAARARVLGIWAACNGLALAVGPTLGGILMQHYGWPGIFLAAIPLGVAAMALAWRA 195 + R + G+ + + VGP +GG++ + W +L IP+ Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMK 187 Query: 196 IPESSDPRGRRWDAGAQAMAAVALAALALAAIESHTTPWLAVVAATVAAMAVAGFIRIER 255 + + +D + +V + L + ++ + ++ + F++ R Sbjct: 188 LLKKEVRIKGHFDIKGIILMSVGIVFFMLFT---TSYSISFLIVSVLSFLI---FVKHIR 241 Query: 256 RAEAAALVPLSLFRSARFCGALAATSAMTFGMYGALFLLPLAWQDSGRFDAVQAGLALMP 315 + V L ++ F + + + G + ++P +D + + G ++ Sbjct: 242 KVT-DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 316 MALVFVLIS-PWSGLLCGRLGRRAMTAGGVAIIGAGLWLIALGAASAALAPALAGLAATG 374 + V+I G+L R G + GV + + + + + + Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV-- 358 Query: 375 LGMGLATGPLMDTAV-SSVPAARAGTASALVNVARMVGATLGVALSGSLYTL 425 LG T ++ T V SS+ AG +L+N + G+A+ G L ++ Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 48.0 bits (114), Expect = 6e-08 Identities = 58/296 (19%), Positives = 105/296 (35%), Gaps = 46/296 (15%) Query: 256 SLVVTDIPDVLDRIGQFIERENQALTRRVRLLFEEI--TVVANDSAEGGIDWKAVYDSAR 313 +L+VT PDV++ + + I Q RR ++L E I V D GI W Sbjct: 320 ALIVTAAPDVMNDLERVI---AQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMT 376 Query: 314 AAVAATLPVA-----------AGGAAAALGATVDS------GPFQGT-RAIVSALSQTGA 355 + LP++ G +++L + + S G +QG +++ALS + Sbjct: 377 QFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTK 436 Query: 356 VLRHSSVPVLTLNRRPVTHAVRTTFSYIDQVQSTAVPGIDAALGSTALPSVSISQKQETV 415 ++ ++TL+ T V + Q+T S ++ +K TV Sbjct: 437 NDILATPSIVTLDNMEATFNVGQEVPVLTGSQTT----------SGDNIFNTVERK--TV 484 Query: 416 GTFLTLVPDAQADGRILLSIAYDNTVAQPIKSVTFGTQGNQIQVQQITIDGNGTVQQVAL 475 G L + P +LL + Q + SV T + V + Sbjct: 485 GIKLKVKPQINEGDSVLL------EIEQEVSSVADAASSTS-SDLGATFNTRTVNNAVLV 537 Query: 476 SPGQPVILSGF--DRRQDEYDRRRLSADAPLLAG--GQDRASSERLTTVVLVTAQV 527 G+ V++ G D D+ L D P++ + ++ + V Sbjct: 538 GSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTV 593 Score = 30.3 bits (68), Expect = 0.021 Identities = 16/63 (25%), Positives = 24/63 (38%), Gaps = 6/63 (9%) Query: 229 ALQAVRVRIL-----PFLTQAGTIADLDGGGS-SLVVTDIPDVLDRIGQFIERENQALTR 282 L V R L AG + + S L++T V+ R+ +ER + A R Sbjct: 133 PLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDR 192 Query: 283 RVR 285 V Sbjct: 193 SVV 195
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 150 bits (380), Expect = 1e-41 Identities = 68/253 (26%), Positives = 113/253 (44%), Gaps = 20/253 (7%) Query: 161 NMVLLDVQVVEIPSARLREFGLQWDALSQGGLHAGGV-WQPGSSLQLAD---------AA 210 VL++ + E+ A G+QW + G +++ A+ ++ Sbjct: 345 PQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSS 404 Query: 211 QPPALSMQGMGAAGYFGVNALLSARLAALAQRGEAVMLAQPQLLARSGTTASFLAGGEVP 270 ALS AAG++ N + L AL+ + +LA P ++ A+F G EVP Sbjct: 405 LASALSSFNGIAAGFYQGN--WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVP 462 Query: 271 Y---STTDAQGNS--STEFKPYGVSLNITPRIDRNGAIRSRIEVEASSIDTSLSVAG--- 322 S T + N + E K G+ L + P+I+ ++ IE E SS+ + S Sbjct: 463 VLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDL 522 Query: 323 GPALRTRRAVTEFNVRSGQTLVLGGFLSRERSHERSGLPVLQDIPLLGALFSSRRDQHKE 382 G TR V SG+T+V+GG L + S +P+L DIP++GALF S + + Sbjct: 523 GATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSK 582 Query: 383 TELAIFVTPRIVS 395 L +F+ P ++ Sbjct: 583 RNLMLFIRPTVIR 595
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 32.1 bits (73), Expect = 0.002 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 12/142 (8%) Query: 97 RLRGRRLARFEQQLPGALLALASALRAGVGVSTALRHIVDHSEPPLAQEFGLMLREQRLG 156 RL LA +QL A+ + A + + AL + SE P ++ R Sbjct: 64 RLSTSDLALLTRQL-------ATLVAASMPLEEALDAVAKQSEKP---HLSQLMAAVRSK 113 Query: 157 VSFDAALARLSQRVPSEASALVAAALRVATHTGGNLAETLDGIARTLRERLQLQGKVR-A 215 V +LA + P L A + A T G+L L+ +A +R Q++ +++ A Sbjct: 114 VMEGHSLADAMKCFPGSFERLYCAMVA-AGETSGHLDAVLNRLADYTEQRQQMRSRIQQA 172 Query: 216 LTAQGRLQAWIVGALPLLLAAV 237 + L + + +LL+ V Sbjct: 173 MIYPCVLTVVAIAVVSILLSVV 194
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 32.1 bits (73), Expect = 0.002 Identities = 13/50 (26%), Positives = 23/50 (46%) Query: 192 MRAGMPRAAALKALADRADSPAVRSWIAALTQADSLGMSLGAVLRGHAAQ 241 + A MP AL A+A +++ P + +AA+ G SL ++ Sbjct: 81 VAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCFPGS 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.013 Identities = 13/70 (18%), Positives = 25/70 (35%), Gaps = 5/70 (7%) Query: 217 RVGAAVGVGAGTEERVEKLAAAGVDVIIVDTAHGHSAGVLERVRWVKQNYPKVEVI---- 272 R G V + + +AA D+++ D + + +K+ P + V+ Sbjct: 25 RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA-FDLLPRIKKARPDLPVLVMSA 83 Query: 273 GGNIATAAAA 282 TA A Sbjct: 84 QNTFMTAIKA 93
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.4 bits (63), Expect = 0.009 Identities = 12/76 (15%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 7 PYLVAAHVTAVVFLVGGLLAQERMVNAISQSPPQEQIGMLAALLRFDRLVTTPA-LLLTW 65 PY + + + + ++M P Q++I ++ + P+ L+L + Sbjct: 463 PYYILP-----ILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYY 517 Query: 66 IFGLSLALSAGWLSSR 81 I + + L R Sbjct: 518 IVSNLVTIIQQQLIYR 533
>PF05043#Transcriptional activator Length = 493 Score = 29.1 bits (65), Expect = 0.022 Identities = 14/53 (26%), Positives = 25/53 (47%) Query: 8 LNLLVTLEALLAEQNVTRAAERLHLSQPAVSTQLSRLRTLFDDPLLIPTQRGM 60 L LL L + + AE L+ ++ AV LS +++ F D + + G+ Sbjct: 13 LELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGI 65
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 168 bits (428), Expect = 1e-53 Identities = 123/256 (48%), Positives = 183/256 (71%), Gaps = 1/256 (0%) Query: 1 MINFTQQQLDAWLLQFLWPFVRMLALVGSAPLFSESTIPIRIKVALAFMLTVAVAPGLEP 60 M+ T +Q +WL + WP +R+LAL+ +AP+ SE ++P R+K+ LA M+T A+AP L Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 PPAIPPGSYAGLWLLGQQVLIGIAMGFTMRIVFAAVQTAGEFVGLQMGLSFASFFDPSTG 120 P S+ LWL QQ+LIGIA+GFTM+ FAAV+TAGE +GLQMGLSFA+F DP++ Sbjct: 61 NDV-PVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 ANTAVLSRLLNIVAMLVFLALDGHLLVLAALVRSFDVLPLTQLTLDPNGWGILVQWGQTI 180 N VL+R+++++A+L+FL +GHL +++ LV +F LP+ L+ N + L + G I Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 181 FVSGLLLALPLICALLTINLAMGILNRAAPQLSVFAVGFPVSLITGLLLLAAVLPHAAPF 240 F++GL+LALPLI LLT+NLA+G+LNR APQLS+F +GFP++L G+ L+AA++P APF Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 241 LEGLMRDGLQAISDVL 256 E L + ++D++ Sbjct: 240 CEHLFSEIFNLLADII 255
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 59.4 bits (144), Expect = 1e-15 Identities = 26/78 (33%), Positives = 44/78 (56%) Query: 4 ETVMSMTYQALKIALAMAGPLLLVTLAVGLVIAVFQAATQINEMTLSFIPKLLAMCGVLV 63 + ++ +AL + L ++G +V +GL++ +FQ TQ+ E TL F KLL +C L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 LMGPWLLGLMTDYIRQLI 81 L+ W ++ Y RQ+I Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 283 bits (725), Expect = 7e-99 Identities = 162/243 (66%), Positives = 190/243 (78%), Gaps = 2/243 (0%) Query: 19 LAAAALAGLALFPAGVVAQATLPALTATPGPGGAQTYSLSMQTLLLMTSLSFLPAALLMM 78 L + A L L AQ LP +T+ P PGG Q++SL +QTL+ +TSL+F+PA LLMM Sbjct: 4 LLSVAPVLLWLITPLAFAQ--LPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMM 61 Query: 79 TGFTRIIIVLGLLRSALGTAMSPPNHVLIGLALFLTFYTMSPVFDRIYSEAYKPLSEGSI 138 T FTRIIIV GLLR+ALGT +PPN VL+GLALFLTF+ MSPV D+IY +AY+P SE I Sbjct: 62 TSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKI 121 Query: 139 PFETAVERAAAPLHTFMLHQTRENDLTLFANLANQPALEDPSQVPMKILVPAFITSELKT 198 + A+E+ A PL FML QTRE DL LFA LAN L+ P VPM+IL+PA++TSELKT Sbjct: 122 SMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKT 181 Query: 199 AFQIGFTIFIPFLIIDLVVASVLMALGMMMVPPVTVALPFKLMLFVLADGWNLLLGSLAS 258 AFQIGFTIFIPFLIIDLV+ASVLMALGMMMVPP T+ALPFKLMLFVL DGW LL+GSLA Sbjct: 182 AFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQ 241 Query: 259 SFY 261 SFY Sbjct: 242 SFY 244
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 136 bits (345), Expect = 5e-44 Identities = 78/133 (58%), Positives = 94/133 (70%), Gaps = 13/133 (9%) Query: 46 DDWAGAMAEQASAASTAPAAAAPAAAPAARPAGGSVFKPLADAAGGNGNDIDLIMDVPVQ 105 D WA A+ EQ + + + A A GG V + D IDLIMD+PV+ Sbjct: 17 DLWADALNEQKATTTKSAADAVFQQL-----GGGDVSGAMQD--------IDLIMDIPVK 63 Query: 106 LTVELGRTRLTIKNLLQLGQGSVVELDGLAGEPMDIFVNGYLIAQGEVVVVEEKYGIRLT 165 LTVELGRTR+TIK LL+L QGSVV LDGLAGEP+DI +NGYLIAQGEVVVV +KYG+R+T Sbjct: 64 LTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRIT 123 Query: 166 DIITPSERINRLN 178 DIITPSER+ RL+ Sbjct: 124 DIITPSERMRRLS 136
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 278 bits (712), Expect = 2e-94 Identities = 97/318 (30%), Positives = 165/318 (51%), Gaps = 8/318 (2%) Query: 7 LSQDEVDALLAGV-TGESDSE-SRDEADARGARAYDLSSPDRVVRRRMQTLELINERFAR 64 LSQDE+D LL + +G++ E +R +D R YD PD+ + +M+TL L++E FAR Sbjct: 5 LSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFAR 64 Query: 65 QLRHLLLNFMRRNADITVGSIKILKYADFERNLPVPSNLNMIQMKPLRGTALFTYDPSLV 124 L +R + V S+ L Y +F R++P PS L +I M PL+G A+ DPS+ Sbjct: 65 LTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSIT 124 Query: 125 FLVIDSLFGGDGRYHTRVEGRDFTTTEQRIIRRLLNLTLESYGKSWEAVYPIEFEYVRSE 184 F +ID LFGG G+ RD T E ++ ++ L + +SW V + + E Sbjct: 125 FSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQIE 182 Query: 185 MHTKFASITGNNEVVVVSSFHIEFGATGGDLNICLPYSMIEPVRDLL-TRPLQETTLEEV 243 + +FA I +E+VV+ + + G G +N C+PY IEP+ L ++ + Sbjct: 183 TNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRRSS 242 Query: 244 DQRWTHQLSRQVRSADVDLTAEFASIPSSIRELLRLKVGDVLPIE---VPETVIANVNGV 300 ++ L ++ + D+D+ AE S+ S+R++L L+VGD++ + V + + ++ Sbjct: 243 TTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGNR 302 Query: 301 PLMECSYGVFNGQYALRV 318 C GV + A ++ Sbjct: 303 KKFLCQPGVVGKKIAAQI 320
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 56.8 bits (136), Expect = 7e-11 Identities = 72/280 (25%), Positives = 99/280 (35%), Gaps = 10/280 (3%) Query: 173 PPAAALALSAAAPANTPAPQTQAPAAARPDTRVPGHELRGAPAPMPNPNAVAVTAVAEAP 232 P A ++ AA A+ + + D L N V P Sbjct: 97 PLTTAQTMALAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLP 156 Query: 233 EHLNAQAAAEAELALQAASAVAQPAGHGAASSHAADAAASLAAAASPQATAPAPMPQAGA 292 L A P + A S A S + A Sbjct: 157 TEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLIT 216 Query: 293 LSLAVATPVAATPAWGADLGRQLVVLSHD------ATRGQHTAELRLDPPDLGPLRVTLS 346 P A P A LG S +GQ +AELRL P DLG ++++L Sbjct: 217 PHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK 276 Query: 347 VNDGVASASFVSAHAAVRHAVEAALPQLHQALAQAGLSLGQANVGEH---GSQSGFDMQQ 403 V+D A VS H VR A+EAALP L LA++G+ LGQ+N+ G Q QQ Sbjct: 277 VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQ 336 Query: 404 QAQGGGHGQGGGTQGDGAVALAPAAATRVARGDGLVDTFA 443 Q+Q + + + D + P + G+ VD FA Sbjct: 337 QSQRTANHEPLAGEDDDTLP-VPVSLQGRVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 67.1 bits (163), Expect = 3e-17 Identities = 51/145 (35%), Positives = 76/145 (52%) Query: 1 MPSQLPLDTLIGLARESTDEAARALGRLNAERSHAERQLSMLQDYRQDYLLRLQNAMQTG 60 M L TL LA + ++AAR LG + AE QL ML DY+ +Y L + M G Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MSAADCHNYQRFIATLDDAIGQQAAVLRQADSHLAQGRVHWQQQQRRLNSFDALAERERR 120 +++ NYQ+FI TL+ AI Q L Q + W+++++RL ++ L ER+ Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AQAVLETRREQRASDEFASRMMFRQ 145 A + E R +Q+ DEFA R R+ Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRK 145
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 91.4 bits (226), Expect = 2e-24 Identities = 60/219 (27%), Positives = 105/219 (47%), Gaps = 6/219 (2%) Query: 23 WRRWQMSSFDLPVEDAIEIVAPPPEPDPGPDPEELLREARAQAEAAGRREGLQQGREQGL 82 W+ W P + + IV P E + E L + AQ + + +QG + G+ Sbjct: 7 WKTWTPDDLAPPQAEFVPIVEP--EETIIEEAEPSLEQQLAQLQM----QAHEQGYQAGI 60 Query: 83 REGRQTGHAEGLAAGREAGYQEGLTQGREQARQEALQLHALAESCGASLADLEARMGQAL 142 EGRQ GH +G G G ++GL + + Q ++ L +L L++ + L Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 143 LTLALDIAGQILRTTLAEQPESMLAAVREVLHINPAATGAMRLWVHPADLELVRQHLADE 202 + +AL+ A Q++ T +++ ++++L P +G +L VHP DL+ V L Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 203 LREGHWRVLADESIARGGCRAETPYGDIDATLQTRWRRI 241 L WR+ D ++ GGC+ GD+DA++ TRW+ + Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQEL 219
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 295 bits (757), Expect = e-101 Identities = 114/333 (34%), Positives = 189/333 (56%), Gaps = 2/333 (0%) Query: 2 KNDGKPLDGVTRSAVLMMSLGEDAAAEVFKYLSAREVQLVGGSMANLKQVTRGDVAVVLE 61 D L G ++A+L++S+G + +++VFKYLS E++ + +A L+ +T VL Sbjct: 9 ILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLL 68 Query: 62 EFRQEADQFMAVTLGSDDYIRTVLTKALGSDRAAGLIEDILEAGEGASGIDALNWLDPHT 121 EF++ + G DY R +L K+LG+ +A +I + L + + + + DP Sbjct: 69 EFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPAN 127 Query: 122 VAELIGDEHPQIIATILVHLERDRAAGVLALLTDRLRNDVMLRIATFGGVQPAALSELTD 181 + I EHPQ IA IL +L+ +A+ +L+ L ++ +V RIA P + E+ Sbjct: 128 ILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVER 187 Query: 182 VLNSVLAGQGA-KRSKMGGVRTAAEILNMMSSAEEEAVVESLRERDSDLAQKIIDEMFVF 240 VL LA + + GGV EI+NM E+ ++ESL E D +LA++I +MFVF Sbjct: 188 VLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVF 247 Query: 241 DNLIDVEDRALQLILKEIDNDSLMVALKGASEELRNKFLRNMSSRAADILREDLEAQGPI 300 ++++ ++DR++Q +L+EID L ALK ++ K +NMS RAA +L+ED+E GP Sbjct: 248 EDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPT 307 Query: 301 RMSKVESEQKKILQIARRLAESGQIVLGNQGDD 333 R VE Q+KI+ + R+L E G+IV+ G++ Sbjct: 308 RRKDVEESQQKIVSLIRKLEEQGEIVISRGGEE 340
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 452 bits (1165), Expect = e-156 Identities = 244/555 (43%), Positives = 351/555 (63%), Gaps = 24/555 (4%) Query: 18 LEKVRALPKPVLLGVAAALVAIVAVLAMWGREPDYKVLFANLDDRDGGAIVSALGQMNVP 77 L ++RA P+ L+ +A VAIV + +W + PDY+ LF+NL D+DGGAIV+ L QMN+P Sbjct: 16 LNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIP 75 Query: 78 YRFSGDGRALLVPADRVYATRMQLAGQGLPRGGSVGFELLDNARFGASQFAEQINYQRGL 137 YRF+ A+ VPAD+V+ R++LA QGLP+GG+VGFELLD +FG SQF+EQ+NYQR L Sbjct: 76 YRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRAL 135 Query: 138 EGELARSIEAMNTVQSARVHLALPRQSLFVRDRQAPTASVLLHLYPGRSLGDAQVAAVAW 197 EGELAR+IE + V+SARVHLA+P+ SLFVR++++P+ASV + L PGR+L + Q++AV Sbjct: 136 EGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVH 195 Query: 198 LVASSVPDLTAENISIVDQNGRLLSAPLGEGRGLDADQSRLRRDIEQRTVERILTILNPL 257 LV+S+V L N+++VDQ+G LL+ GR L+ Q + D+E R RI IL+P+ Sbjct: 196 LVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPI 255 Query: 258 VGPGNVQAQASAEMDFARREQTSEVYRPNQEPGQAAVRSKQTSDSLQTGIDPAQGVPGAL 317 VG GNV AQ +A++DFA +EQT E Y PN + +A +RS+Q + S Q G GVPGAL Sbjct: 256 VGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGAL 315 Query: 318 SNQPPAAAQAPIVNPPAAPQAAQGGQPGQLAQAGQNAAQGAATQAAPRLPTNNRNDATIN 377 SNQP +API PP Q AQ + +A P + + + T N Sbjct: 316 SNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAG-----------PRSTQRNETSN 364 Query: 378 YEVDRTISHVKQPVGMLKRLSVAVVVNYLPDSSGEPQPLPEEELTKLTNLVREAMGYSEA 437 YEVDRTI H K VG ++RLSVAVVVNY + G+P PL +++ ++ +L REAMG+S+ Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 438 RGDSLNLVNSQFN---DKPVKPPFWRDPELLDLVKTVLAWVFGLALALWLYRR-LRPAVS 493 RGD+LN+VNS F+ + + PFW+ +D + W+ L +A L+R+ +RP ++ Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 494 NYL-NPPVDPEEAEARRQEMQREAQAAA--------RAKEVNRYEDNLQRARDMATKDPR 544 + E+A+ R++ + + RA + E QR R+M+ DPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 545 AVAMVMRAWMTQDEK 559 VA+V+R WM+ D + Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 61.2 bits (148), Expect = 8e-16 Identities = 49/108 (45%), Positives = 72/108 (66%), Gaps = 6/108 (5%) Query: 4 SGLSGIESMLQQMRAVVQAAQSNGVSPAELAPQPA-SFAAELQRSLQRVSAAQIAATNQG 62 S + GIE ++ Q++A +A++ E PQP SFA +L +L R+S Q AA Q Sbjct: 1 SAIQGIEGVISQLQATAMSARAQ-----ESLPQPTISFAGQLHAALDRISDTQTAARTQA 55 Query: 63 KAYELGAPGVSLNDVMIDLQKSSIAFQTAVQVRNRLVAAYKEISAMSV 110 + + LG PGV+LNDVM D+QK+S++ Q +QVRN+LVAAY+E+ +M V Sbjct: 56 EKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 75.6 bits (186), Expect = 9e-20 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%) Query: 16 AVALSYGEHDT-APRVVAKGYGQIADTIVRTAREHGLYVHESRELV-SLLMQVDLDAHIP 73 A+ + Y +T P V K T+ + A E G+ + + L +L +D +IP Sbjct: 268 AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIP 327 Query: 74 PQLYAAVAELLAWLYRLET 92 + A AE+L WL R Sbjct: 328 AEQIEATAEVLRWLERQNI 346
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.7 bits (69), Expect = 0.010 Identities = 21/93 (22%), Positives = 27/93 (29%), Gaps = 2/93 (2%) Query: 119 QAPPAQGKAPLWQPAPPPGPSAAAPDAGNSVRPAPAAA--GTASSSAANPATDPAAASSR 176 Q PP P +P P P P AP +P P P + Sbjct: 67 QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPA 126 Query: 177 SPATGGRPALPAGAGAQATQATQATHAGAPALP 209 SP PA P + A A + T + Sbjct: 127 SPFENTAPARPTSSTATAATSKPVTSVASGPRA 159
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.007 Identities = 43/247 (17%), Positives = 88/247 (35%), Gaps = 25/247 (10%) Query: 191 DAKLIADHYAKEHELAKKQETAQTIKNELGGSVEDISKIEG-ILLLKQKDA---EKKQVL 246 L A+ A A ++ + N I +E L+ + A + + Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 247 LDAFDFRAQDKDRTKKVVDEVDERIAALNSERYSLSQNRKKVQASLQEDQILFSPDEAQR 306 ++ + + ++ A L + L+ NR+ ++ L +A R Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL----------DASR 322 Query: 307 LFGEAGVLFQGQIKKDFQQLIAFNRAITDERRGYLQEEFAEIEGELKRVNAELNALGKKR 366 EA + Q++ + Q+L N+ R+ L+ + K++ AE L + Sbjct: 323 ---EA----KKQLEAEHQKLEEQNKISEASRQS-LRRDLDASREAKKQLEAEHQKL--EE 372 Query: 367 SEMLSFLSGTDVFTKYKQLSDEMVTLRADITSLEHQKGHLHRLQELRAEIRSLTE-ERDH 425 +S S + + + + + L +L + E + LTE E+ Sbjct: 373 QNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAE 432 Query: 426 LQARIEA 432 LQA++EA Sbjct: 433 LQAKLEA 439
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 74.9 bits (184), Expect = 9e-17 Identities = 76/318 (23%), Positives = 127/318 (39%), Gaps = 17/318 (5%) Query: 49 LFLLAGLAALGALATNIILPAFPDMAVALGTSVIDLSATLSSFLVAFAVGQLFVGP---- 104 L ++ AL A+ +I+P P + L S D++A L +A+ Q P Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSN-DVTAHYGILLALYALMQFACAPVLGA 65 Query: 105 LSDRFGRRWLVLAGLLAFVIGSAICAFASTLPQLIGGRVVQALGVCATSVLSRAIARDLF 164 LSDRFGRR ++L L + AI A A L L GR+V + +V IA D+ Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DIT 124 Query: 165 DGEALARTLTLIMVAMAAAPGFSPMLGGALSSWLGWQFTFAFVGVMAVVLAIHYNARLGE 224 DG+ AR + P+LGG + F + + + L E Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 225 THQADRRSAISIPAILKTYWQLLTDRRFIAPALTMSLVSGSLYAFFGMAPAILMVGFHFS 284 +H+ +RR ++ +A + + + G PA L V F Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAALWVIFGED 239 Query: 285 PFGL---AIFFASTVFVVFGA---GLLVPRLAHRWGQARAVRVGLVIALTGSIVLLVGKE 338 F I + F + + ++ +A R G+ RA+ +G++ TG I+L Sbjct: 240 RFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 339 DFVFFSAALMVFLLGMGM 356 ++ F +++ G+GM Sbjct: 300 GWMAFPIMVLLASGGIGM 317
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 1/121 (0%) Query: 60 ASISFAMAIAQLVWGAAQPLFGAAADRWGPGRVIVIGAVMLAAGSALTTQVSSQWGLIFT 119 AS ++ L + ++G +D+ G R+++ G ++ GS + S + L+ Sbjct: 49 ASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIM 108 Query: 120 VGLLSAAGAGAGSFSILIGATAQRIPSERRSFAGGVINAGGSMGQFIFAPLNQAVMLAFG 179 + AGA A ++++ A+ IP E R A G+I + +MG+ + + + Sbjct: 109 ARFIQGAGA-AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH 167 Query: 180 W 180 W Sbjct: 168 W 168
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 41.9 bits (98), Expect = 6e-07 Identities = 39/198 (19%), Positives = 66/198 (33%), Gaps = 22/198 (11%) Query: 7 RRALIVVDVQNEYFGGKLPIEYPDPQQSLANIGRAMDAAHAAGVPIVLV---QDIEPAES 63 R L++ D+Q YF + ANI + + G+P+V P + Sbjct: 30 RAVLLIHDMQ-NYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 64 PL----FARGSHGAELHESVVSR----PHDHHVVKGMPSAFAGTGLEAWLAERGIDTITV 115 L + G + E +++ D + K SAF T L + + G D + + Sbjct: 89 ALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLII 148 Query: 116 VGYMTHNCDDSTVKHAVHAGLRVEVLNDATGSVPYANSAGQASAEEIHRVLTVVMQSRFA 175 G H T A ++ + DA + E H++ R A Sbjct: 149 TGIYAHIGCLVTACEAFMEDIKAFFVGDAVADF----------SLEKHQMALEYAAGRCA 198 Query: 176 AVMSTAQWIAGLNGAPMP 193 + T + L AP Sbjct: 199 FTVMTDSLLDQLQNAPAD 216
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.4 bits (76), Expect = 0.001 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 10/126 (7%) Query: 226 GGQAQYVEQPVPASVGADRLSGVLAWVSAHLDRAHDLDSLAARAAMSRRTFTRHFRQATG 285 G + Q + G D +SG+L+ +SA + + D+ A + T G Sbjct: 226 GNKLQNLPNLDNIGAGLDTVSGILSAISASFILS-NADADTRTKAAAGVELTTKVLGNVG 284 Query: 286 GTVGQWLLSQRLALAQRLLETSDAPVETIAAQAGFG-TPLS---LRQHFRRALKVSPSAY 341 + Q++++QR A L TS A IA+ +PLS + F+RA K+ Y Sbjct: 285 KGISQYIIAQRAAQG---LSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKI--EEY 339 Query: 342 RREFRQ 347 + F++ Sbjct: 340 SQRFKK 345
>SECA#SecA protein signature. Length = 901 Score = 30.6 bits (69), Expect = 0.026 Identities = 18/77 (23%), Positives = 32/77 (41%), Gaps = 5/77 (6%) Query: 294 RLLQGDV-----GSGKTVVAAIAAAQAIACGAQVALMAPTEILAEQHFRKLVSWLQPLGV 348 L + + G GKT+ A + A G V ++ + LA++ + LG+ Sbjct: 93 VLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGL 152 Query: 349 NVAWLSGSLTAKARRQA 365 V + A A+R+A Sbjct: 153 TVGINLPGMPAPAKREA 169
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 143 bits (361), Expect = 2e-46 Identities = 50/144 (34%), Positives = 76/144 (52%) Query: 23 DRTAIAGELSKVLADSYTLYLMTHNFHWNVTGPLFNTLHQMFMTQYSEEWAALDDIAERI 82 ++T + L+ L++ + LY H FHW V GP F TLH+ F Y +D IAER+ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68 Query: 83 RALGVHAPGTYREFSKLSSISEPGAVPDAMEMVRLLVKGNEAVSKTARAAFDKADSANDQ 142 A+G T +E+++ +SI++ G A EMV+ LV + +S ++ A+ D Sbjct: 69 LAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEENQDN 128 Query: 143 PTADLLTQRMDIHEKNAWMLRSLL 166 TADL ++ EK WML S L Sbjct: 129 ATADLFVGLIEEVEKQVWMLSSYL 152
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 74.3 bits (182), Expect = 7e-18 Identities = 56/211 (26%), Positives = 85/211 (40%), Gaps = 13/211 (6%) Query: 2 LITGATGSIGGALALEYAKAGVDTLILQGRRTERLAELAQLCRREGAQVETHALDVRDHA 61 ITGA IG A+A A G + E+L ++ + E E DVRD A Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVD-YNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 62 SLIAWLTQICEVHAPDLVIVNAGININVGSDRQGEIWQDVHELLDVNVKAAFATVHGVLP 121 ++ +I P ++VN + G ++ VN F V Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD-EEWEATFSVNSTGVFNASRSVSK 129 Query: 122 FMRKRGQGQIALVSSLAAWRGLPETP--SYSASKAAIKVYGEAMRDGLAAEGIRFNVIMP 179 +M R G I V S A G+P T +Y++SKAA ++ + + LA IR N++ P Sbjct: 130 YMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 180 GYVESPMCFDMPGPKPFLWTAARAAHAIRRG 210 G E+ M + LW A + +G Sbjct: 188 GSTETDM-------QWSLWADENGAEQVIKG 211
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.006 Identities = 21/175 (12%), Positives = 56/175 (32%), Gaps = 12/175 (6%) Query: 150 AQQTLDIMLQESERFVNELSHRMAREQMNFAKSELANARRAYEERREALLTFQSANSLLD 209 Q I+ + E N+L ++ F R +E T+Q+ Sbjct: 149 EQTRYQILSRSIEL--NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQ--KYQ 204 Query: 210 AEAAAKARAEVISELEASLTKERTTLKGLLATLDSNTPQVRQQ---RNRIQAMEQQLAAE 266 E + + A + + + + LD + + +Q ++ + E + Sbjct: 205 KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 267 TRRLVSQQGGDKLNVVASQYRNLTIDAAIAEEAYKFAVSSVETARIEASKKLRSL 321 L + +L + S+ + + + + +K + + + + + L Sbjct: 265 VNELRVYKS--QLEQIESEILSAKEEYQLVTQLFK---NEILDKLRQTTDNIGLL 314
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 36.1 bits (83), Expect = 9e-05 Identities = 48/197 (24%), Positives = 86/197 (43%), Gaps = 15/197 (7%) Query: 37 LFEPIAHITFLMFLMTVVRGRHLPGFDYPIYLLTGLVPFFLMRNISLKMMEA----INAN 92 L EP+ ++ L + V+ GR + G Y +L G+V M + + + A + Sbjct: 39 LAEPLIYLFGLGAGLGVMVGR-VGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQ 97 Query: 93 RPLFA--YPNIKPFDTFLARLI---VECSLSACIYVLLLCAMGFWLGYDISIHAPLSWFV 147 R A Y ++ D L + + +L+ ++ A+G+ + P V Sbjct: 98 RTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLYALP----V 153 Query: 148 ALLTGIAFAFGLGLVLCVVGEAMPNSKTFIRLMFLPLYLISGVIFPIWILPIRYMEWLLW 207 LTG+AFA LG+V+ + + + L+ P+ +SG +FP+ LPI + + Sbjct: 154 IALTGLAFA-SLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARF 212 Query: 208 NPYLHIIDNLRYSVFEH 224 P H ID +R + H Sbjct: 213 LPLSHSIDLIRPIMLGH 229
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.025 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 37 LIGRNGAGKSTLMRLLGGLD 56 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 79.4 bits (196), Expect = 7e-19 Identities = 40/195 (20%), Positives = 76/195 (38%), Gaps = 36/195 (18%) Query: 6 TILITGGTGSFGNTFVPMTLAKY---NPKKVIIFSRDEMKQ-WDMARKFH-----DDPRV 56 L+TG G F+ ++K +V+ D + +D++ K P Sbjct: 2 KYLVTGAAG-----FIGFHVSKRLLEAGHQVVGI--DNLNDYYDVSLKQARLELLAQPGF 54 Query: 57 RFFIGDVRDRERLYRALD--GVDYVVHAAATKIVPTAEYNPFECVKTNVDGAMNLIDACI 114 +F D+ DRE + + V + V + NP +N+ G +N+++ C Sbjct: 55 QFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR 114 Query: 115 DKGVKRVVALST---------------DKASSPINLYGATKLASDKLFVAGNAYSGEHGT 159 ++ ++ S+ D P++LY ATK A++ + + YS +G Sbjct: 115 HNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELM---AHTYSHLYGL 171 Query: 160 RFAVVRYGNVMGSRG 174 +R+ V G G Sbjct: 172 PATGLRFFTVYGPWG 186
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-15 Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 9/134 (6%) Query: 760 LSGVAIMVADDQEDARGLVAEVLADRGAAVHTCASGADVLAALRQASWPDLLVCDISLGD 819 ++G I+VADD R ++ + L+ G V ++ A + + DL+V D+ + D Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPD 59 Query: 820 MEGYELIGRIRALEAERGAPLGERMPAVALSGHTGPEDRLRALLAGFQIHVAKPVDPREL 879 ++L+ RI+ +P + +S ++A G ++ KP D EL Sbjct: 60 ENAFDLLPRIKK--------ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Query: 880 LATVSAMLRPDTRR 893 + + L RR Sbjct: 112 IGIIGRALAEPKRR 125
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.6 bits (206), Expect = 2e-21 Identities = 46/187 (24%), Positives = 74/187 (39%), Gaps = 2/187 (1%) Query: 7 LAGRVVLVTGGGSGLGAAICDMLAAEGASVVVADLDETRAHDCARRLSERGAAACATVMD 66 + G++ +TG G+G A+ LA++GA + D + + L A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VGDPEQVAAALDLAMQRYGKLDAVVNNAGIDVTASIDELDVAAWERVLRTNLTGPFLVAK 126 V D + + G +D +VN AG+ I L WE N TG F ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 LARNRLTPH--GHIVNIASTAARRAWPNASAYHASKWGLLGLSHALHAELRGMGLKVSAV 184 + G IV + S A + +AY +SK + + L EL ++ + V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 185 IAGGMRT 191 G T Sbjct: 186 SPGSTET 192
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 176 bits (447), Expect = 1e-54 Identities = 79/335 (23%), Positives = 129/335 (38%), Gaps = 35/335 (10%) Query: 6 RALVAGGAGFLGAHLCRRLLLQGWEVICVDNFHTGRSENL----AGLAAHPGLTVIRQDI 61 + LV G AGF+G H+ +RLL G +V+ +DN + +L L A PG + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 62 A-LPLPAEL----HIDCIYNLACPASPVHYQ-ADPVATLQTCVQGATQLLELAARTG-AR 114 A +L H + ++ + V Y +P A + + G +LE Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 115 ILQASTSEVYGDPLEHPQREGYWGHVNPVGPRSCYDEGKRCAETLFMEYGRRRGVVVKIA 174 +L AS+S VYG + P + P S Y K+ E + Y G+ Sbjct: 121 LLYASSSSVYGLNRKMPFST----DDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 175 RIFNTYGPGMAADDGRVVSNFIVQALAGHPLTVYGDGSQTRSFCYVDDLVDGLLRLMNSP 234 R F YGP D + F L G + VY G R F Y+DD+ + ++RL + Sbjct: 177 RFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 235 DQFSQPV-----------------NLGNPAEISVLRMAELVRELTGSRAPLQFRDLPRDD 277 N+GN + + ++ + + + G A L D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 278 PTHRCPDITLAREQLRWRPTTPLSAGLARTVDYFR 312 D E + + P T + G+ V+++R Sbjct: 295 VLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.017 Identities = 12/61 (19%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 210 KAGKLATELGTLIAKAERRR-DAQRGGQAPATAAPAAPAPA-PAATRPQAEPAPPSAQTE 267 + T+ + K E+ + + ++ + P + +P +PQAEPA + T Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 268 S 268 + Sbjct: 1154 N 1154
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 40.8 bits (95), Expect = 2e-05 Identities = 58/246 (23%), Positives = 90/246 (36%), Gaps = 33/246 (13%) Query: 482 AALHTAQAERQGLLARLGAVSLAEAETRAAAHERARRDLDMARQHLRIQAPEGVDALRAA 541 AA+H L + A A A+ A A +A+ + D Q L+ E ALR Sbjct: 49 AAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNE---ALRHN 105 Query: 542 QRQAHERRAQLQALRAGLPDAAAPVSLEQAQQALRAATAEAGHAAQEVVSARTALDTQQA 601 + A A + + L +A++ R A A QE R ++ ++A Sbjct: 106 ASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKA 165 Query: 602 STQVLQAQWTARQGEFDAAGRAAQREQRGARLVEARARRDTLAQRAQAAQAALQAHQPEI 661 T+ A E+R A L E A+ + AQ L A Q E+ Sbjct: 166 ETE-------------RQLKLAEAEEKRLAALSEE-------AKAVEIAQKKLSAAQSEV 205 Query: 662 IEQDARRFEQSAALARDAHQRRHAELLQLQGKLEQAQAQGLGEQLLQAQADAQRLARRRD 721 ++ D ++ L+ H R AE+ L GK +L QA A + L Sbjct: 206 VKMDGEIKTLNSRLSSSIHARD-AEMKTLAGKR---------NELAQASAKYKELDELVK 255 Query: 722 EFAMRA 727 + + RA Sbjct: 256 KLSPRA 261
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 2e-16 Identities = 28/180 (15%), Positives = 73/180 (40%), Gaps = 15/180 (8%) Query: 12 LGRPARPQRADSRDAMLDVATALFAAQGVAATTIAHIARRADVTPAMVHYYFKNREQLID 71 + R + + ++R +LDVA LF+ QGV++T++ IA+ A VT ++++FK++ L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 72 VVVAERLAPVIASVWAPAALPAGNGPGAAPPTPPEPRAMVAQVVARIMQCAAERP----W 127 + + + P +P +++ +++ +++ Sbjct: 61 EIWELSESNIGELE-----------LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLL 109 Query: 128 LAPLWMREVVNEGGQLREKVFRYLPVERLHAFAATITSAQQQGAVNPGIEPRLVFLSILG 187 + ++ + + ++ R L +E T+ + + + R + + G Sbjct: 110 MEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRG 169
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.2 bits (120), Expect = 6e-09 Identities = 37/280 (13%), Positives = 82/280 (29%), Gaps = 25/280 (8%) Query: 64 ARGQQVQAGAPLFALEADPEAQAQREARARLASAQAQRQDLATGKRAPEVDVVRAQLAQA 123 ++V L + + + L +A+R + E + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 124 EAEAKRAAAQLARDRVQFQAGGIARAQLDDSRAQAQSSAARVRELRAQLQVAGLPGR--- 180 + + +A+ V Q A + ++Q L A+ + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 181 --DEQLRAQDAQVEAARAGLAQADWALAQKQVAAAQAARVFD-TLYRVGEWVPAGSPVVR 237 ++LR + LA+ + + A + +V ++ G V ++ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Query: 238 LLPPGN-IKLRFFVPETALGGLRSGQAVRARCDACGE----PVAATISYIAAEAEYTPPV 292 ++P + +++ V +G + GQ + +A + + I +A Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA------ 412 Query: 293 IYSRDSRGKLVYMV------EAHPAPRDATRLHPGQPVEV 326 D R LV+ V L G V Sbjct: 413 --IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTA 450
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.0 bits (64), Expect = 0.027 Identities = 12/38 (31%), Positives = 24/38 (63%) Query: 128 QAVEQALEGLGLQSRANQLTGSLSGGWKQRLALAACLL 165 +A+ +ALEGLG+ + ++ GS+ G +A+ A ++ Sbjct: 387 KAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIV 424
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 50.7 bits (121), Expect = 2e-09 Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 2/173 (1%) Query: 208 AMTRERERGTMENLLATPVRPLEVMTGKIVPYIAIGLIQATIILLAALYVFHVPLMGSLL 267 A R + T E +L T +R +++ G++ + I + A + + + SLL Sbjct: 90 AFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL-SLL 148 Query: 268 AVYLAALLFVAANLTVGITLSSLAQNQLQAMQLTMFYFLPNILLSGFMFPFQGMPVWAQH 327 L A ++G+ +++LA + + P + LSG +FP +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 328 IGNLLPLTYFNRLIRGILLKGNGWADLWPHVWPLLLFTALIMALAVKFYRRTL 380 LPL++ LIR I+L D+ HV L ++ + L+ RR L Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIPFFLSTALLRRRL 260
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.012 Identities = 21/184 (11%), Positives = 49/184 (26%), Gaps = 27/184 (14%) Query: 302 PLGVPSQLTRQRPDILAAEALWHRAAADVGVATANLYPRFTLTGSFGSQRTRAGDVADGV 361 LG + + + +L A R N P L Q +V Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL--- 185 Query: 362 NVWSLALGLTQPLFHGGELRARRRAAEAAYQAAAAAYRDTVLQGLQQVADALSAVQADAD 421 L + + + +Q L + V A + Sbjct: 186 -----------------RLTSLIKEQFSTWQNQKYQKE----LNLDKKRAERLTVLARIN 224 Query: 422 TLQARAEAERQAEAAYRITAQQYQAGGVSQLALLDAQREQLRTRAERIQAQADRHADTAA 481 + + E+ + + +++ A+L+ + + + E ++ + Sbjct: 225 RYENLSRVEKSRLDDFSSLLHK---QAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESE 281 Query: 482 LLQA 485 +L A Sbjct: 282 ILSA 285 Score = 30.2 bits (68), Expect = 0.024 Identities = 16/116 (13%), Positives = 38/116 (32%), Gaps = 6/116 (5%) Query: 372 QPLFHGGELRAR--RRAAEAAY-QAAAAAYRDTVLQGLQQVADALSAVQADADTLQARAE 428 L L A +++ QA R +L ++ D Q +E Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 429 AERQAEAAYRITAQQYQAGGVSQLALLDAQREQLRTRAERIQAQADRHADTAALLQ 484 E + +Q+ +Q + ++ R + A+ +R+ + + + + Sbjct: 182 EEVLRLTSLI--KEQFSTWQ-NQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 5e-11 Identities = 34/207 (16%), Positives = 68/207 (32%), Gaps = 17/207 (8%) Query: 88 QLAYDQAQAAVRARQVARDQAARDARRNRSLGKLVSAEALEQSQARLQQAEAALAEAEVQ 147 + Y +A +R + +Q + + +LV+ + +L+Q + ++ Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 148 RATARLNLARSRVVAPTDGRVTNLDLR-VGSYATAAHAVMALV-DASSFYVEGYFEETKL 205 A S + AP +V L + G T A +M +V + + V + + Sbjct: 318 LAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDI 377 Query: 206 AQIHEGDAVSVTLMGDSRQIHGHVQSIALGI-ADR--DRGTGANLLPNVNPTFNWVRLAQ 262 I+ G + + +G++ I D D+ G V Sbjct: 378 GFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGL------------VFNVI 425 Query: 263 RIPVRVQIDEVPKGVRLVAGQTATVEI 289 + K + L +G T EI Sbjct: 426 ISIEENCLSTGNKNIPLSSGMAVTAEI 452 Score = 55.2 bits (133), Expect = 9e-11 Identities = 28/172 (16%), Positives = 60/172 (34%), Gaps = 20/172 (11%) Query: 4 LNTLRRPVVGKFFVTALTV--CAAVYAGWQLWTHYEVE-----PWTRDGRVKAYVVQVAP 56 L + PV + + A + + + E+ T GR K + P Sbjct: 46 LELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKP 101 Query: 57 DVSGLVTAVPVHDNQDVKAGDVLFEIDRARFQLAYDQAQAAVRARQV--ARDQAARDARR 114 + +V + V + + V+ GDVL ++ + + Q+++ ++ R Q + Sbjct: 102 IENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIE 161 Query: 115 NRSLGKLV-------SAEALEQSQARLQQAEAALAEAEVQRATARLNLARSR 159 L +L + E+ + + + Q+ LNL + R Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR 213
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 48.6 bits (116), Expect = 1e-08 Identities = 41/197 (20%), Positives = 69/197 (35%), Gaps = 34/197 (17%) Query: 81 QIKQILDAGAQT---LLVPMIQSAEEAAAAVSAMRYPPHGVRGLGSALARASRWNRIPDY 137 Q++ +L A ++ PMI + EE A + M+ + G ++ + Sbjct: 374 QLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVG----- 428 Query: 138 AQRANDEMCLLVQIETPRGLQALDEILALEGVDGVFIGPADL----------SASMGYLS 187 + +E P A + + VD IG DL + + YL Sbjct: 429 -----------IMVEIPSTAVAANLFA--KEVDFFSIGTNDLIQYTMAADRMNERVSYLY 475 Query: 188 NPDHPDVCAAIDDAIVRIARAGKAAGI---LHGDPAQARHYLDLGATFVAVGVDATLLAR 244 P HP + +D I GK G+ + GD L LG ++ + L AR Sbjct: 476 QPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPAR 535 Query: 245 AAEKLAQSFKDQPAAQA 261 + + +P AQ Sbjct: 536 SQLLKLSKEELKPFAQK 552
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (298), Expect = 1e-38 Identities = 37/89 (41%), Positives = 52/89 (58%) Query: 9 TKAELAELLFERVGLNKREAKDIVDTFFEEIRDALARGDSVKLSGFGNFQVRNKPPRPGR 68 K +L + E L K+++ VD F + LA+G+ V+L GFGNF+VR + R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 69 NPKTGETIPIAARRVVTFHASQKLKSVVE 97 NP+TGE I I A +V F A + LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>adhesinb#Adhesin B signature. Length = 310 Score = 30.2 bits (68), Expect = 0.011 Identities = 8/38 (21%), Positives = 16/38 (42%) Query: 44 KGLAKLDPDQKRELGARINQAKQRIEALLNERRAQLAQ 81 K L++ DP K + +++ AL E + + Sbjct: 157 KRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNN 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.3 bits (71), Expect = 0.009 Identities = 48/245 (19%), Positives = 77/245 (31%), Gaps = 36/245 (14%) Query: 127 PVGAPLALALAVAREQPDATLVLPADSATVAAWVPGLQVLAAGA---------LAEVAAH 177 P L + + +PD +++ + T + + GA L E+ Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASE---KGAYDYLPKPFDLTELIGI 114 Query: 178 LSGAAPLPRAEPGAWPAAAASPCLSDVRGQPM--ARRALEVAAAGAHSLLMVGPPGAGKS 235 + A P+ P + R M R L +L++ G G GK Sbjct: 115 IGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174 Query: 236 MLAQRLPGLLPPLSRTQALEAAALAGLAGPAGMAAALQGQPPFRAPHHGASAAALVGGGA 295 ++A+ L R A +A + + + L G H A G Sbjct: 175 LVARALHDYGK--RRNGPFVAINMAAIPRDL-IESELFG--------HEKGAFT---GAQ 220 Query: 296 RPRPGEATLAHHGVLFLDELPEFDRRALEALREPLETG---RVAIARARHSVQYPARFQL 352 G A G LFLDE+ + A L L+ G V + ++ Sbjct: 221 TRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPI-----RSDVRI 275 Query: 353 VAAMN 357 VAA N Sbjct: 276 VAATN 280
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.040 Identities = 31/187 (16%), Positives = 54/187 (28%), Gaps = 15/187 (8%) Query: 30 APSAPDTAAAAVQPSAQSDHTTQSRPQRPASAQPAAAT-VGQADPFAVLDCQAREYNDTL 88 A PS S++ +R PA AT + A Q + + Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 89 ALAVTFTQPVDRKAGLDSFLNVV-DTGAVKASEDGQDAAAA------SKASVVAAGAAAA 141 T T +R+ ++ NV +T + ++ G + A+V A Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 142 QGRPVQGAWVVGDN------PRMVYFPYVQPQRSYAVRLRAALPGAQAGATLGADLQCSV 195 + Q V P +P R + P +Q T Q + Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT-ADTEQPAK 1173 Query: 196 QTPAMPP 202 +T + Sbjct: 1174 ETSSNVE 1180
>FLAGELLIN#Flagellin signature. Length = 507 Score = 28.1 bits (62), Expect = 0.025 Identities = 8/41 (19%), Positives = 18/41 (43%), Gaps = 2/41 (4%) Query: 158 AFGILIAIPAMIAHRYLRGRVDGLLNAMEQIAA--RVARAS 196 A I +++ L L +A+E++++ R+ A Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAK 41
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 6e-15 Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 4/121 (3%) Query: 45 DRLRIAILDDHPVITLGVAAYLRSQPDFDIVHAETTSEALVRSLKHQPCDVAVVDFYLPR 104 I + DD I + L S+ +D+ + + D+ V D +P Sbjct: 2 TGATILVADDDAAIRTVLNQAL-SRAGYDVRITSNAATLWRW-IAAGDGDLVVTDVVMPD 59 Query: 105 QPWDGMDFIRRLRRQHPHMAIITFSAGAPAETEYAAFRAGAHGYLPKSASMPVLVEVIRA 164 + + D + R+++ P + ++ SA T A GA+ YLPK + L+ +I Sbjct: 60 E--NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 165 A 165 A Sbjct: 118 A 118
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 67.8 bits (165), Expect = 2e-15 Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 6/196 (3%) Query: 1 MADHSINGKVALIAGGAKNLGGLIARDLAGQGARAVVIHYNSASSREAAEATVAAVQTSG 60 M I GK+A I G A+ +G +AR LA QGA + YN E E V++++ Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNP----EKLEKVVSSLKAEA 56 Query: 61 AQGVALQGDLTTAGAVEKLFADAIAAVGRPDIAINTVGKVLKKPFTEITEAEYDEMAAIN 120 A D+ + A++++ A +G DI +N G + +++ E++ ++N Sbjct: 57 RHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116 Query: 121 SKAAFFFLKEAGRHVND--NGKIVTLVTSLLGAFTPFYAAYAGSKAPVEHYTRAAAKEFG 178 S F + +++ D +G IVT+ ++ G AAYA SKA +T+ E Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 ARGISVNAVGPGPMDT 194 I N V PG +T Sbjct: 177 EYNIRCNIVSPGSTET 192
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 168 bits (427), Expect = 8e-57 Identities = 65/142 (45%), Positives = 89/142 (62%), Gaps = 8/142 (5%) Query: 17 RPRARQQGFTLIEIMVVIVIMGILAALVVPRVLDRPDQARRVAARQDISGLMQALKLYRL 76 R +Q+GFTL+EIMVVIVI+G+LA+LVVP ++ ++A + A DI L AL +Y+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 77 DNGRYPNAAQGLQALVRRP---DGARNWRP--YLDRLPDDPWGHPYQYLNPGVKGEIDVF 131 DN YP QGL++LV P A N+ Y+ RLP DPWG+ Y +NPG G D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 132 TFGPDNKAGGEEDDADIGSWDL 153 + GPD + G E+ DI +W L Sbjct: 122 SAGPDGEMGTED---DITNWGL 140
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 51.9 bits (124), Expect = 5e-11 Identities = 17/90 (18%), Positives = 32/90 (35%) Query: 8 ISERGFTLIEMLVVVAIIAIAASMVGLSVTSSSGRALRADAERLVDAFAVAQSEARSDGR 67 + +RGFTL+EM++++ ++ ++A MV L+ +S + R Q G+ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 68 AILWRADERGWSFERRGRPARVSAQDDGPQ 97 W F Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDG 90
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.6 bits (95), Expect = 2e-07 Identities = 20/64 (31%), Positives = 39/64 (60%), Gaps = 3/64 (4%) Query: 1 MPSSRQQRGFTLIEVLVALAIISVAMGAAMRATQVMLDNSRAIRDKTLALLAA-DNTLAR 59 M ++ +QRGFTL+E++V + II V A++ +M + +A + K ++ + A +N L Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVL--ASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58 Query: 60 LRLE 63 +L+ Sbjct: 59 YKLD 62
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.008 Identities = 9/27 (33%), Positives = 19/27 (70%) Query: 5 RRCAPQQGFTLIEVLIAIALMALVSLL 31 R Q+GFTL+E+++ I ++ +++ L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASL 28
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.2 bits (62), Expect = 0.009 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 42 RAWHQANADQLAAKRATAEAVRQAERAAR-LEAFTDATIRAVAAMLEDGHTLDEACKSLI 100 +A +A A A ++A AEA R+AE AR A A A+ A T A + LI Sbjct: 211 KASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVAT--AAGRGLI 268 Query: 101 GNAFRFGACHETLNELVAIL 120 A + + +++ +A+L Sbjct: 269 QVAQGAASLAQAISDAIAVL 288
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.7 bits (103), Expect = 8e-07 Identities = 27/140 (19%), Positives = 59/140 (42%), Gaps = 1/140 (0%) Query: 41 DAFIVAAFLPLMAADLGVTPSVAGHSVTAFAVAYALLAPVIATLTARVPRRTLLCVSLAL 100 + ++ LP +A D P+ TAF + +++ V L+ ++ + LL + + Sbjct: 29 NEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIII 88 Query: 101 LGAANIGSALATSM-PWLIASRIAAAATAAAYTPNAGAVAAALVRTDFRARALAIVIGGL 159 ++ + S LI +R A AAA+ V A + + R +A ++ + Sbjct: 89 NCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIV 148 Query: 160 TVATALGVPLGRVASTMLSW 179 + +G +G + + + W Sbjct: 149 AMGEGVGPAIGGMIAHYIHW 168 Score = 31.4 bits (71), Expect = 0.006 Identities = 20/103 (19%), Positives = 39/103 (37%), Gaps = 2/103 (1%) Query: 283 YLSGVGTDRRGARRVLLTAYLIMAVALGGLAWLAASAEPMLPITAALVGLWGASSWAQSP 342 Y+ G+ DRRG VL ++V+ ++L + +T +V + G S+ ++ Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETT--SWFMTIIIVFVLGGLSFTKTV 368 Query: 343 AQQHRLIASAPQHGALVVALNASAIYFGIALGTAIGARLVETG 385 + Q ++L + G AI L+ Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 37.4 bits (87), Expect = 3e-05 Identities = 24/135 (17%), Positives = 49/135 (36%), Gaps = 13/135 (9%) Query: 112 ALDSLRVAEALDRRLQAEGRALDVFVQVNTSNEASKFGLPPEQAAAFVRELPAYSSLRVR 171 + S +AL LD++++VN+ ++ G P++ ++L A +++ Sbjct: 99 CVHSNWQLKALQNARL--KAPLDIYLKVNSG--MNRLGFQPDRVLTVWQQLRAMANVGEM 154 Query: 172 GLMTLALFSPDPALVRPCFVRLRELRDRLRQEAPAGIAIDELSMGMSGDYALAIEEGATT 231 LM+ + P + R+ + + L S+ S E Sbjct: 155 TLMSHFAEAEHPDGISGAMARIEQAAEGLEC---------RRSLSNSAATLWHPEAHFDW 205 Query: 232 VRVGQAIFGARALPD 246 VR G ++GA Sbjct: 206 VRPGIILYGASPSGQ 220
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.9 bits (67), Expect = 0.019 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 6/41 (14%) Query: 299 QVDVARDIAAQLAQGESRIIGVMIESHLEEGRQDLKPGVPL 339 +VD+ DI G SR G++IE E R DL PL Sbjct: 278 EVDLVLDI------GNSRTCGILIERFPGETRVDLTRSFPL 312
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 27.6 bits (61), Expect = 0.025 Identities = 9/18 (50%), Positives = 13/18 (72%) Query: 42 DVLVDGHNRYELCRKHGI 59 D LV GH+R E+C K+ + Sbjct: 53 DYLVGGHSRKEVCEKYQM 70
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (325), Expect = 8e-35 Identities = 85/407 (20%), Positives = 171/407 (42%), Gaps = 16/407 (3%) Query: 14 LMVLCLGVLMIVLDTTIVNVALPSIRADLQFSETALVWVVNAYMLTFGGFLLLGGRLGDL 73 L+ LC+ VL+ ++NV+LP I D + WV A+MLTF + G+L D Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 74 YGPRRVFLAGLTLFTAASLACGVAGSQ-QLLVAARAVQGLGGAVVSAVSLSLIMNLFSEP 132 G +R+ L G+ + S+ V S LL+ AR +QG G A A+ + +++ + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVM-VVVARYIPK 134 Query: 133 AERARAMGVYGFVCAGGGSVGVLLGGVLTSALSWHWIFLVNLPIGAAVSGLCMLLLPGGR 192 R +A G+ G + A G VG +GG++ + HW +L+ +P+ ++ ++ L + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLL-KK 191 Query: 193 AAGGEARLDVAGAVSVTLSLMLAVYAVVNGNEAGWTSTHTIGLLAASAALLATFLVVESR 252 + D+ G + +++ ++ + T++++I L S F+ + Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 253 TSAPLMPLGLFRLRNLAIANVVGVLWAGAMFAWFFISALYMQLVLGYSAMQVGLAFLPGN 312 + P + GL + I + G + G + + + M+ V S ++G + Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 313 LIMAVCSLGVSARLVMRFGIRAPLAAGLAIAAVGLALFAQAPIDGRFALHILPGMLLLGL 372 + + + LV R G L G+ +V + + + + +LG Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLL-ETTSWFMTIIIVFVLGG 361 Query: 373 GAGIAFNPLLLAAMNDVPAHESGLASGVVNTAFMMGGALGLAILASL 419 + + + + E+G ++N + G+AI+ L Sbjct: 362 LSFTKTVISTIVSSSLKQQ-EAGAGMSLLNFTSFLSEGTGIAIVGGL 407 Score = 29.8 bits (67), Expect = 0.023 Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 1/107 (0%) Query: 57 MLTFGGFLLLGGRLGDLYGPRRVFLAGLTLFTAASLACG-VAGSQQLLVAARAVQGLGGA 115 ++ F +GG L D GP V G+T + + L + + + V LGG Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 116 VVSAVSLSLIMNLFSEPAERARAMGVYGFVCAGGGSVGVLLGGVLTS 162 + +S I++ + E M + F G+ + G L S Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 4e-05 Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 10/67 (14%) Query: 70 SAWH----VVQVQVAPDHQGQGLGARLLRGVLEQA---DAAGLPAQLDVLKTN-PARRLY 121 S W+ + + VA D++ +G+G LL +E A GL L+ N A Y Sbjct: 84 SNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGL--MLETQDINISACHFY 141 Query: 122 ERLGFRV 128 + F + Sbjct: 142 AKHHFII 148
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.009 Identities = 14/68 (20%), Positives = 26/68 (38%) Query: 19 SPVAALAQAAPAAQPPTQAQPAIQPSEEQLQKFASASQKVAMVADEYRPKLQAAKDDAAR 78 + VA Q + A EE+ + +Q+V V + PK + ++ + Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 79 EQVYREAD 86 + RE D Sbjct: 1143 AEPAREND 1150
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 70.0 bits (171), Expect = 1e-15 Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 37/166 (22%) Query: 164 GEPPSAPKIEPEPEPTQPEPPSIAELGLDDLGDGVDVIVNEKSISFRISNELLFPSGQAV 223 G+ +AP + P P P P + F + +++LF +A Sbjct: 192 GQGEAAPVVAPAPAP---APEVQTK-------------------HFTLKSDVLFNFNKAT 229 Query: 224 LSPAGLGLISRMAKVINR--SQGYPVSVEGHSDPVPIQTRQFPSNWELSAGRATSVLREL 281 L P G + ++ ++ + V V G++D I + + N LS RA SV+ L Sbjct: 230 LKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--NQGLSERRAQSVVDYL 285 Query: 282 VRDGVDPGRLRAVGYADTHPIASN--DTPQGRAA-------NRRVE 318 + G+ ++ A G +++P+ N D + RAA +RRVE Sbjct: 286 ISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVE 331
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 8e-12 Identities = 26/128 (20%), Positives = 46/128 (35%) Query: 19 RDALVEATEAILAERGLEGFTLREAARRVGVSAAAPLHHFGSAAGLLTEVAILGFEALTR 78 R +++ + +++G+ +L E A+ GV+ A HF + L +E+ L + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 79 HLREGARSGGNDPGARLRAQGMGYVRFALAHPARFQLMFRKDRLTDDARLAAASQAAFAE 138 E DP + LR + + + R LM + A Q A Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 139 LEQAIRDY 146 L D Sbjct: 133 LCLESYDR 140
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.032 Identities = 10/20 (50%), Positives = 12/20 (60%) Query: 369 FVGPSGSGKSTLVKLLLGLY 388 G G GKSTL+ L+GL Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 8e-09 Identities = 66/290 (22%), Positives = 105/290 (36%), Gaps = 19/290 (6%) Query: 51 GASAAQTGYLQTAQTLPFLLLSLPAGVLADRVSRRGLMTAAEALRAA--ALLGLLTLLWM 108 A G L L + G L+DR RR ++ + A A A++ LW+ Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWV 98 Query: 109 RALNLAWLAALGFAGAIGTVVYNVAAPALVPTLVPAARLGAANRWLELARSSAFAAGPAV 168 L + + A G GA G V A A + + ++ AGP + Sbjct: 99 --LYIGRIVA-GITGATGAV-----AGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 169 GGALVGTMGAPVAYMLAAALSLLAVMWLAGLPASSAPARRHQHPLRELAEGARYVATHAL 228 GG L+G + AAAL+ L + L S R L A + + Sbjct: 151 GG-LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM 209 Query: 229 LRPILITAIFFNTAWFILQ---AIYVAYAIDALALDAGQVGLTLGVYGA-GMVAGALAAP 284 + A+FF + Q A++V + D DA +G++L +G +A A+ Sbjct: 210 TVVAALMAVFF-IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITG 268 Query: 285 CLARRLPFGGVIAAGPLAALVAAALMLGTLAWPSGLLAGAAFFLFGAGPI 334 +A RL + G +A L+ G +A L +G I Sbjct: 269 PVAARLGERRALMLGMIADGTGYILLAFAT---RGWMAFPIMVLLASGGI 315
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 76.1 bits (187), Expect = 4e-17 Identities = 45/192 (23%), Positives = 84/192 (43%), Gaps = 3/192 (1%) Query: 11 SFSDEGAPPPHVPLWLLALFTFSGTLAMHIFVPALAMAGHDLNAGNGAMQMTVSLYIIGL 70 S+S + +WL L FS M + +L +D N + + +++ Sbjct: 4 SYSQSNLRHNQILIWLCILSFFSVLNEM-VLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 71 AVGQLIYGPLSDRYGRRRVLMVGLAIYTVAGLAAALAPQVYA-LIAARLFQALGGCAGLV 129 ++G +YG LSD+ G +R+L+ G+ I + + ++ LI AR Q G A Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 130 LGRAMVRDTAAPSEAAKRLALMNLMVTVAPGVAPIVGGALAASLGWRAVLFVLCVLGVVN 189 L +V K L+ +V + GV P +GG +A + W + L ++ ++ ++ Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW-SYLLLIPMITIIT 181 Query: 190 FMFAWRLLPETG 201 F +LL + Sbjct: 182 VPFLMKLLKKEV 193 Score = 30.2 bits (68), Expect = 0.016 Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 3/101 (2%) Query: 76 IYGPLSDRYGRRRVLMVGLAIYTVAGLAAALAPQVYALIAARLFQALGG--CAGLVLGRA 133 I G L DR G VL +G+ +V+ L A+ + + + + G + Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 134 MVRDTAAPSEAAKRLALMNLMVTVAPGVAP-IVGGALAASL 173 +V + EA ++L+N ++ G IVGG L+ L Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>PF06291#Lambda prophage Bor protein Length = 102 Score = 27.7 bits (61), Expect = 0.013 Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 27 FTLLTMALAAALAGCAAQRDAPESPPSAAAPATEV 61 L + ALA + GCA Q + P+A P + Sbjct: 8 KMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETI 42
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.3 bits (164), Expect = 3e-16 Identities = 33/175 (18%), Positives = 61/175 (34%), Gaps = 5/175 (2%) Query: 4 ETTRTQIMQHAQRLIQERGCNGFSYRDLAALIGIKTSSIHYYFPQKEDLLLAVVQHYHAR 63 + TR I+ A RL ++G + S ++A G+ +I+++F K DL + + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 64 WQATIAAIDPGLRAD--AKLRAYV-QVHQQAFCGTARICLAATL--AAELASLPQAVRQA 118 D + LR + V + R L + E V+QA Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 119 VQDFYRANEDWLACVLEQGAREGSLRVPGDLRSAAQATFAALQGSLVSARLFNNS 173 ++ + D + L+ L R AA + G + + S Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184
>PF03944#delta endotoxin Length = 633 Score = 26.6 bits (58), Expect = 0.008 Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 29 IKGVSDLLFEVMGKPRNSTFVVIEEV--DMDSWGVGGVTVAEYRKH 72 ++G LL + + N I +V + D WG+ T+ YR + Sbjct: 166 MQGYQLLLLPLFAQAANLHLSFIRDVILNADEWGISAATLRTYRDY 211
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 81.3 bits (200), Expect = 1e-20 Identities = 60/254 (23%), Positives = 103/254 (40%), Gaps = 26/254 (10%) Query: 6 KVAIVTGASQGLGAGIVESYRKRGFAVIANSRN----LKPSSDADVVA-----VPGDIGN 56 K+A +TGA+QG+G + + +G + A N K S A P D+ + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 RDVAKQLVETAISRYGRVDTLINNAGIFIAKPFTQYTVEDMDRVFRTNLHGFFHVTQFAL 116 ++ G +D L+N AG+ + E+ + F N G F+ ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 EQMLKQERGHIVQITTTLVRQAIAGLDVGLTMLTKGGLEAVTRGLAIEYAKQGIRVNAVA 176 + M+ + G IV + + + +K T+ L +E A+ IR N V+ Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSM--AAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 177 PGIINTPMH-------DPQAHDFLGGMH------PMGRMGEIADIAKAVMYL--EEADFV 221 PG T M + G + P+ ++ + +DIA AV++L +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 222 TGETLNVDGGQQAG 235 T L VDGG G Sbjct: 247 TMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.9 bits (57), Expect = 0.014 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 2/36 (5%) Query: 10 QEFMLEAVRMVRGGQSMAAVAKILGISPKTLHNWVK 45 +L A+ RG Q AA +LG++ TL ++ Sbjct: 438 YPLILAALTATRGNQIKAA--DLLGLNRNTLRKKIR 471
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.019 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%) Query: 81 RVLGGGLVAGAVVLIGGDPGIGKSTLLLQALATMSAH--SRVLYVTGEESAEQVALRARR 138 RV+ G V++ G GIGKST L+ L + + TG++S EQ+ A Sbjct: 587 RVMEPGCKFDYSVVLEGTGGIGKST-LINTLVGLDFFSDTHFDIGTGKDSYEQI---AGI 642 Query: 139 LGLQTGNVNLLAEIRLEAIQAAVS 162 + + + EA++A S Sbjct: 643 VAYELSEMTAFRRADAEAVKAFFS 666
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 126 bits (317), Expect = 1e-37 Identities = 77/257 (29%), Positives = 124/257 (48%), Gaps = 25/257 (9%) Query: 1 MKDKCVLVTGATKGIGWALTQKLADLGCHVVGIARNTDHID----------FPGYLYACD 50 ++ K +TGA +GIG A+ + LA G H+ + N + ++ + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 51 LADAGRTEEVLREI-REKFPVDAIVNNVGVVRPQPLGEIDLASLYNVMDLNVRVAVQVTQ 109 + D+ +E+ I RE P+D +VN GV+RP + + +N ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 110 AFVESMKVRRTGRIVNVSSRAIHGGLDRTS---YSAAKSALIGCTRTWALELAEYGVTVN 166 + + M RR+G IV V S + RTS Y+++K+A + T+ LELAEY + N Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAG--VPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 167 AVAPGPIETELFRV--------AQPAGSDGEKRALASIPMKRLGTPAEVAAAIAFLLSDE 218 V+PG ET++ Q E IP+K+L P+++A A+ FL+S + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTG-IPLKKLAKPSDIADAVLFLVSGQ 242 Query: 219 AGFITGQVLGVDGGGSL 235 AG IT L VDGG +L Sbjct: 243 AGHITMHNLCVDGGATL 259
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 379 bits (976), Expect = e-133 Identities = 197/373 (52%), Positives = 239/373 (64%), Gaps = 21/373 (5%) Query: 1 MPRPIHASISLAALAHNLDVVRRHLDQAAQAAGGAPPSIWAVIKANAYGHGIEAAVAGFS 60 M RPI AS+ L AL NL +VR+ A +W+V+KANAYGHGIE + Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHAR---------VWSVVKANAYGHGIERIWSAIG 51 Query: 61 AAQGLAMLDLAEAVRCREAGWGGPILLLEGFFQPADLDLIDRYHLSATVHTREQLDMLAQ 120 A G A+L+L EA+ RE GW GPIL+LEGFF DL++ D++ L+ VH+ QL L Sbjct: 52 ATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQN 111 Query: 121 ARLSRRVDIMLKLNSGMNRLGFDPDAYGSAHARALQLREQGVVGAVGRMTHFACADGTPG 180 ARL +DI LK+NSGMNRLGF PD QLR VG + M+HFA A+ G Sbjct: 112 ARLKAPLDIYLKVNSGMNRLGFQPD---RVLTVWQQLRAMANVGEMTLMSHFAEAEHPDG 168 Query: 181 VAGQLRVFQSVTQGLADGPVSVCNSAATLRYPEIAVAHGAQAHWVRPGICLYGASPFAD- 239 ++G + + +GL + S+ NSAATL +PE A WVRPGI LYGASP Sbjct: 169 ISGAMARIEQAAEGL-ECRRSLSNSAATLWHPE------AHFDWVRPGIILYGASPSGQW 221 Query: 240 ADAASFGLRPAMSLRSQIIGVQDLPAGAEVGYGATFRAERPMRVGVVACGYADGYPRHAG 299 D A+ GLRP M+L S+IIGVQ L AG VGYG + A R+G+VA GYADGYPRHA Sbjct: 222 RDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAP 281 Query: 300 TGTPVVVGGVRTRLVGRVSMDMLMVDLDPVPAAGIGTPVSLWGQDGPSVDEVAQAAGTIG 359 TGTPV+V GVRT VG VSMDML VDL P P AGIGTPV LWG+ +D+VA AAGT+G Sbjct: 282 TGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGK-EIKIDDVAAAAGTVG 340 Query: 360 YELLCALAPRVPV 372 YEL+CALA RVPV Sbjct: 341 YELMCALALRVPV 353
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 2e-04 Identities = 42/196 (21%), Positives = 70/196 (35%), Gaps = 34/196 (17%) Query: 561 EEIAEVVSRATGIPVAKMMQGEREKLLQMEDHLHKRVVGQDEAVRLVSDAIRRSRAGLAD 620 E+ ++ RA P + + E + M +VG+ A++ + + R L Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDSQDGMP------LVGRSAAMQEIYRVLAR----LMQ 158 Query: 621 PSRPYGSFLFLGPTGVGKTELTRALADFLFDSEEHMIRIDMSEFMEKHSVARLIGAPPGY 680 + G +G GK + RAL D+ + I+M+ + L Sbjct: 159 TDLT---LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESEL------- 208 Query: 681 VGYEEGGYLTEAVRRKPYSV-------VLLDEVEKAHPDVFNVLLQVLDDG---RLTDGQ 730 G+E+G + T A R + LDE+ D LL+VL G + Sbjct: 209 FGHEKGAF-TGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRT 267 Query: 731 GRTVDFRNTVIVMTSN 746 D R IV +N Sbjct: 268 PIRSDVR---IVAATN 280
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.9 bits (67), Expect = 0.003 Identities = 12/52 (23%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 84 IAVAPDCQGRGIGSMLVIEGLARLRGRGAAGC------VVLGRPHYYSRFGF 129 IAVA D + +G+G+ L+ + + + G + + H+Y++ F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.2 bits (68), Expect = 0.014 Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 4/96 (4%) Query: 275 FFAGALVKRWGLPTMLGLGMAINVAS---AGVAIASTSLPAFYAALFFLGVGWNFMFVGG 331 + G LV R G +L +G+ S A + +TS +F LG G +F Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVI 369 Query: 332 TTLLAQSYRPAERGRAQGAAEMLRYAATALATLAAG 367 +T+++ S + E G + + G Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.2 bits (65), Expect = 0.047 Identities = 20/96 (20%), Positives = 26/96 (27%), Gaps = 1/96 (1%) Query: 240 PPGVRVALPMSDEHLGHTGPTTWSLEQARMPESAYAHAMGQPSQPIGLDAAVAAFDRLGL 299 + P H + E R A + AA+ F + Sbjct: 42 RSFRFIERPEGAAEGRHRTLYPLTGEAERDAPILAATTPEDDEYSVRPLAALEPFLEKWV 101 Query: 300 -APGYAINVPHGAAGVYTGSVYPSDLARQRVVHLDQ 334 P + GA G PS AR R V L Q Sbjct: 102 PIPVLRLKNQRGAGGEELYDPGPSSWARLRTVELPQ 137
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 108 bits (272), Expect = 8e-28 Identities = 78/408 (19%), Positives = 164/408 (40%), Gaps = 19/408 (4%) Query: 24 LLALAIGCVMAMLDVTVVNVALPSIGAQLGTPLSGLVWIIDGYTLAFAALLLAAGALSDH 83 L+ L I ++L+ V+NV+LP I P + W+ + L F+ G LSD Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 84 YGARPVYLAGLALFTLASLLCGAAPST-GLLVTARLLQGVGAALFMPSSLSLLMHAYQVP 142 G + + L G+ + S++ S LL+ AR +QG GAA F P+ + +++ Y Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIPK 134 Query: 143 EVRGRMLAAWSAIITVAATAGPLAGGMLIDLFGWRSIFLINLPL-GLAGLWLARAHLESP 201 E RG+ +I+ + GP GGM+ W +L+ +P+ + + L+ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 202 AARPRPLNPGNHLLGIGMLGLASYALIQG-NVYGWTAPRIVTAGVLALACGAALLARERR 260 + + GI ++ + + Y + ++++ + R+ Sbjct: 193 VRIKGHFD----IKGIILMSVGIVFFMLFTTSYSISFL------IVSVLSFLIFVKHIRK 242 Query: 261 HPHPIVPRALAQTPGYLATNTYGFLVSFSVYGLIFLLSLYVQQALGADALQAGLKLLPVF 320 P V L + ++ G ++ +V G + ++ ++ + G ++ Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 321 GVFSI-GNLAAGRLAVRWGARATMLVGAAIGALAAIATAILCAPDSPYLLLVILLGVGNL 379 + I G L R G + +G +++ + + L S ++ ++I+ +G L Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 380 ATGAAIPAMTALALQIGGAAHANSAAAALNANRQAGALVGVAAIGGVL 427 + + ++ + A + + LN G+A +GG+L Sbjct: 363 SFTKTV--ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.003 Identities = 9/15 (60%), Positives = 9/15 (60%) Query: 12 CPCGSGLAYSACCER 26 CPCGSG Y C R Sbjct: 885 CPCGSGKKYKQCHGR 899
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 37.7 bits (87), Expect = 2e-04 Identities = 35/150 (23%), Positives = 54/150 (36%), Gaps = 18/150 (12%) Query: 53 ATMAVSAIAQPEHPPERPPDAAEAESALADARKQIDEIRKHLEDGGEDAQLVQWRADVLD 112 AT S + E+ A A A A A+ D + + L+D +A R + Sbjct: 53 ATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEA----LRHNASR 108 Query: 113 IQSRAD-ALAEALAPQLASMTARLTELGEPPAGTREAPDVAAQRAQLQKSSRALDSQTKL 171 S + A A A Q RL + E EA + A Q A+ ++ ++ Sbjct: 109 TPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRK--------EI 160 Query: 172 ARLLSVEAAQTAEQIS-TLRRNQFQARLGE 200 R E A+T Q+ + A L E Sbjct: 161 ER----EKAETERQLKLAEAEEKRLAALSE 186
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 28.8 bits (64), Expect = 0.029 Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 256 YESLPAPYKAALAAAARETSAALRQHIL 283 + + P LA A R T A R+H+L Sbjct: 14 WRTHLQPQDPTLAQAVRATIAKHREHLL 41
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 2e-16 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 5/111 (4%) Query: 1 MPAMNELNSPSTREIILDTAEALFARQGHDGTSMRQITSEAGVNLAAVNYHFGSKEALVQ 60 M + + TR+ ILD A LF++QG TS+ +I AGV A+ +HF K L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AVLKRRLAVLNQERLRLLDELEARAGGEPLK-PSQIVDAFFGTLLRLAARP 110 + + + + + L E +A+ G+PL +I+ + + R Sbjct: 61 EIWELSESNIGE----LELEYQAKFPGDPLSVLREILIHVLESTVTEERRR 107
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.0 bits (57), Expect = 0.005 Identities = 11/27 (40%), Positives = 12/27 (44%) Query: 2 LCALTVFACLLGGCAVYTPDGAVIVDP 28 L AL + LL GCA D DP Sbjct: 5 LSALALGTTLLVGCASSGTDQQGRSDP 31
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.6 bits (214), Expect = 2e-22 Identities = 64/259 (24%), Positives = 111/259 (42%), Gaps = 20/259 (7%) Query: 4 VSLVTGAGRGLGRNTALSIARRGGDVIITYRSGKDAAEGVVADVHALGRKAVALQLDTAE 63 ++ +TGA +G+G A ++A +G + + E VV+ + A R A A D + Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 64 VASFPTFVHAVRAALRQNWQRET--FDHLVNNAGHGEMADFAATTEAQFDALFNVHVKGV 121 A+ + +RE D LVN AG + ++ +++A F+V+ GV Sbjct: 69 SAAI--------DEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 122 FFLTQALLPLLAD--GGRIVNLSSGLTRVSFPGFSAYSAAKGAVETLTVYMAKELGSRGI 179 F ++++ + D G IV + S V +AY+++K A T + EL I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 180 TANAVAPGAIETDFL-------GGAVRDTPDYNKAFADITALGRVGVPDDIGPMIANLLS 232 N V+PG+ ETD GA + + F L ++ P DI + L+S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 233 ADNRWVNGQRIEVSGGQSI 251 + + V GG ++ Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 37.6 bits (87), Expect = 9e-05 Identities = 20/123 (16%), Positives = 28/123 (22%), Gaps = 3/123 (2%) Query: 391 PATALQAPAAATPRPEAVAATAASPAAPAAAAPVASATAAPVAQAAAAAPPPPAAVQPRA 450 P + A P+AV P P P Sbjct: 49 PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPV 108 Query: 451 GAASGAAPAAPAVPVAQTA---NPAPQAQGAAPAAPVSSAPAAQPAAADTPPWEDLPATP 507 V + N AP ++ A +S P A+ + P P Sbjct: 109 KKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYP 168 Query: 508 AAA 510 A A Sbjct: 169 ARA 171 Score = 35.3 bits (81), Expect = 6e-04 Identities = 24/132 (18%), Positives = 34/132 (25%), Gaps = 10/132 (7%) Query: 417 APAAAAPVASATAAPVAQAAAAAPPPPAAVQPRAGAASGAAPAAPAVPVAQTANPAPQAQ 476 AP + VA A PP AVQP P P+ + AP Sbjct: 40 VIELPAPAQPISVTMVAPADL---EPPQAVQPP--PEPVVEPEPEPEPIPEPPKEAPVVI 94 Query: 477 GAAPAAPVSSAPAAQPAAADTPPWEDLPATPAAAEPAAAAKAPPAAALAVTPPAAQAKAP 536 P + + + + PA+ A P ++ A P Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSS-----TATAATSKP 149 Query: 537 PPDADGEPPAWV 548 P A Sbjct: 150 VTSVASGPRALS 161
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 1e-15 Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 17/186 (9%) Query: 26 AVLTAAREVFLTHGFSAATTDMIQRAAGVSKATVYAYYPTKQALFEAVIEGKCAEHM--A 83 +L A +F G S+ + I +AAGV++ +Y ++ K LF + E ++ Sbjct: 15 HILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE-LSESNIGEL 73 Query: 84 TLRSLRSVPGAIHAVLSELANAYLEFGVAPEGLALFRV-------SAAEAPRFPELARAF 136 L PG +VL E+ LE V E L E + R Sbjct: 74 ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNL 133 Query: 137 FENGPEAYCGIVAEHVERGVRNQELHLGDVSPQEAARLFFSLVRGQAQLEGVLLPDRRPS 196 + + +E L D+ + AA + + G +E L + Sbjct: 134 CLESYDRIEQTLKHCIEAK----MLPA-DLMTRRAAIIMRGYISG--LMENWLFAPQSFD 186 Query: 197 EAQKKR 202 ++ R Sbjct: 187 LKKEAR 192
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.017 Identities = 27/155 (17%), Positives = 52/155 (33%), Gaps = 8/155 (5%) Query: 70 LDALVARAWDGNLDLQAAAARVEQSRARAGVALAQL--FPRVDLDASLTRGAISENGPMA 127 L AL A A AR+EQ+R + +L P + L +SE + Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 128 ALGAPTSTTDLWRAGFQADWEIDLWGRLRRQREGAVATLQATLYEQRSAQVALSAE---I 184 W+ + E++L + R +R +A + R + L + Sbjct: 187 LTSLIKEQFSTWQNQ-KYQKELNL-DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 185 ARQYVA-LRGVQTRLDIARRNQEIAAHLLRLTETR 218 +Q +A ++ E+ + +L + Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.6 bits (87), Expect = 1e-04 Identities = 68/411 (16%), Positives = 144/411 (35%), Gaps = 40/411 (9%) Query: 37 INNRVGALALADIRGAGGFGLDDASWITTAYTAGELIAMPLAPWFAVTLSLRRFHL--QM 94 +N V ++L DI +W+ TA+ I + + L ++R L + Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 95 LAAGAAIAGVLPFVHDLRLLLLLRGLQGVASGALIPLLMMAALRFFPPSIRLFALALYSM 154 + ++ G + LL++ R +QG + A L+M+ R+ P R A L Sbjct: 88 INCFGSVIGFVGHSF-FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGS 146 Query: 155 TATFAPNVSTWLTGLWTDQLVDLRMVYWQIVPINLLAGLLVAWGIPQDRPLPERFRHANW 214 V + G+ + Y ++P+ + + + + R Sbjct: 147 IVAMGEGVGPAIGGMIAHY---IHWSYLLLIPMITIITVPFLMKLL-----KKEVRIKGH 198 Query: 215 LGMAFGGAGLLLLAIGIEQGNRLEWFTSPLVCTSLSAGSLLL---AFYLFTEWHHPT--P 269 + G++L+++GI L TS S L++ +F +F + P Sbjct: 199 FDI----KGIILMSVGI--------VFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 270 FIKLQLLKRRNLWLGFSLFLCLLVIFLSGSLLPATLLGHAWHYRALQSAPIGLMIGLPQL 329 F+ L K +G + + ++ L +A IG +I P Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ---LSTAEIGSVIIFP-G 302 Query: 330 VVAPAVAMLLYQKWVDARA---VMAAGMAITAAACLLGAQVTNQWMWPEFALAQGLQAVG 386 ++ + + VD R V+ G+ + + L + + W + + V Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW---FMTIIIVFVL 359 Query: 387 QPMAIVAMLF--LATSMVAPQEGPYVSGIVNLLRALGAPLGSALISRVIEL 435 ++ + + +S + QE ++N L G A++ ++ + Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 106 bits (266), Expect = 1e-27 Identities = 50/415 (12%), Positives = 118/415 (28%), Gaps = 84/415 (20%) Query: 4 SKKTKLAGSATVMVAAVALAL-IFNRPESAAATQSTDDAYIRAEITSVAPEITGLVEAVL 62 S++ +L + +A L + + E A + P +V+ ++ Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGK--LTHSGRSKEIKPIENSIVKEII 111 Query: 63 VEENQPVRAGQLLV---------------------------------------------- 76 V+E + VR G +L+ Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 77 ------QIDDREYVLAERNAAAALAHARAAADGIHAQIEVQQSVIRQAQSTIEADQATRE 130 + + E + + + ++ +++ + I + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 131 LARLDYSRYKSLAADGSGTVQARQQAKARL---------------QVEKAQQTKDQAILQ 175 + + + SL + A + + + Q+E + + Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 176 AQKGRQAALQADLLRAQAEIRQAEAALAQARLDLSRTRITAPIAGTIGHKRVR-VGNYAR 234 + + + L + I LA+ + I AP++ + +V G Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT 351 Query: 235 TGDPLLTLVPLTDIY-IEANFRETQLARMRQGQPVRVTVDALPGRTF---TGTVQSLGPA 290 T + L+ +VP D + A + + + GQ + V+A P + G V+++ Sbjct: 352 TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLD 411 Query: 291 SGVSYSVIAPHNATGNFTKIVQRLPVRIALDPQQDGADQLRVGMSVQPEVDVNAR 345 + G ++ + + L GM+V E+ R Sbjct: 412 A-------IEDQRLGLVFNVIISIEENCLS--TGNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.028 Identities = 31/173 (17%), Positives = 62/173 (35%), Gaps = 3/173 (1%) Query: 37 VMNLFAVQTVAPVIAASLGLGLDSVGVLAMLPQLGYALGLVLLVPLADRLENRRLIGATL 96 V+N + P IA S + L +++G + L+D+L +RL+ + Sbjct: 27 VLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGI 86 Query: 97 AVCALCMLAAAFAPGGA--VFMAAVFAGGASTCAIQMLVPMAAFMAAPERRGATVGNVMS 154 + + + MA G + +++ + A E RG G + S Sbjct: 87 IINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGS 146 Query: 155 GLMVGVLLSRPLSNLVVDAWGWRALYLVFAGGMAATGVALLCLLPQRRPHDGP 207 + +G + + ++ W L L+ + T L+ LL + G Sbjct: 147 IVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITI-ITVPFLMKLLKKEVRIKGH 198
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 29.0 bits (65), Expect = 0.027 Identities = 23/99 (23%), Positives = 34/99 (34%), Gaps = 9/99 (9%) Query: 5 RLSLRPRLGRVAGRLVLLAAACAVAAAAHAQG----YISRKLDVPVPGGVAVVALGTAER 60 L R R+AG V L ACA AA A + R L AV L E Sbjct: 13 TQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLAD---DPQAVADLSRFEN 69 Query: 61 APQASYGGHRVMVLRDSDGQWIAVVGIALDAKPGRHTLQ 99 + G +RV + + ++A + + + Sbjct: 70 GQELPPGTYRVDIY--LNNGYMATRDVTFNTGDSEQGIV 106
>cloacin#Cloacin signature. Length = 551 Score = 25.8 bits (56), Expect = 0.035 Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 19 KSSLNDAENLLREAASSSGDKATELRDRAMASLKRTREALYDAQDAVLERGRKAARATDD 78 ++ +N+ + AA D L AM S K+ + A++ + + K + D Sbjct: 401 QTDVNNKQAAFDAAAKEKSDADAAL-SSAMESRKKKEDKKRSAENNLNDEKNKPRKGFKD 459 Query: 79 YVHD 82 Y HD Sbjct: 460 YGHD 463
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.0 bits (246), Expect = 3e-27 Identities = 68/254 (26%), Positives = 107/254 (42%), Gaps = 25/254 (9%) Query: 5 KVALITAGGSGMGAAAARKLAADGYRV-AILSSSGKGEALASELQGLGVTGSNLEPDDIA 63 K+A IT G+G A AR LA+ G + A+ + K E + S L+ P D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-PADVR 67 Query: 64 --RLVDAAMQRW----GRVDAVVNSAGHGPKGKLLDIPDADWHLGMEYYLLNVVRITRLV 117 +D R G +D +VN AG G + + D +W V +R V Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 APIMRQQRGGSIVNISTYATFEPEALFPTSGVFRAGLAAFTKVFADEYAADNVRMNNVLP 177 + M +R GSIV + + P +A FTK E A N+R N V P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 178 GFIDS------LPEKDDRRQR-----------IPMGRYGRADEVAELIAFLASDKSGYIT 220 G ++ +++ Q IP+ + + ++A+ + FL S ++G+IT Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 221 GQNIRIDGGITRSV 234 N+ +DGG T V Sbjct: 248 MHNLCVDGGATLGV 261
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.5 bits (68), Expect = 0.005 Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 10/60 (16%) Query: 155 VPALAPLKNEMTGPATKATPAE-PAQKPDQGPPAQPEGAPDGFSANPATDGFSQTRDGEP 213 +P ++P +N PA P E P +P+ P P+ PD ANP TDG TR P Sbjct: 328 LPEVSPAEN----PANNPAPNENPGTRPN--PEPDPDLNPD---ANPDTDGQPGTRPDSP 378
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 32.3 bits (73), Expect = 0.006 Identities = 16/113 (14%), Positives = 39/113 (34%), Gaps = 15/113 (13%) Query: 644 LHDGRRIINLYDECQHPLKDRHFQEDMQDASRTIRKKNGVLAFATQEPGAITENP----- 698 + + + + ++ + P+ + ++ D I K +G + + NP Sbjct: 11 FENAKEVFLISEDLKTPINITNSNSNLSDGLYVIDKGDGWILGEPSVVSSQILNPNETGT 70 Query: 699 VGPSLVQQTATLILLPNPRAKARDYIE-----GFGL-----SPTEFELLKSLG 741 SL + I + ++I+ GFG+ + E + + G Sbjct: 71 FSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFGITIGEQNTIERSVSTTAG 123
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 173 bits (440), Expect = 2e-56 Identities = 73/231 (31%), Positives = 111/231 (48%), Gaps = 7/231 (3%) Query: 1 MSASLKSEDVAAYLEQSRGLERDHLGELVSSRKRAWQVAIGAGLIALASVAAVAGLTPLK 60 M+ + +++ AY E++ ERD L S+K AW VA AG +A A V AVA LTPLK Sbjct: 1 MAVGIPKDELKAYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLK 60 Query: 61 QPPEMYVVRVDSATGSIEHVSSLGQPLED-YGQRIAKYFLNTYVLNCEGYSWQTIQEQFD 119 E YV+ VD TG + L Y + + KYFL TYV EG+ +E FD Sbjct: 61 T-VEPYVITVDRNTGEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFD 119 Query: 120 TCALLSSAPIQTQYGKRFEGQ--DAVTTRLGTQGTVDVQVHSITLGANQAAIVRFTKTER 177 ++S+ P Q ++ + ++ + L + V V++ ++ A V FTK Sbjct: 120 AVMVMSARPEQDRWSRFYKTDNPQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESV 179 Query: 178 EVSTGNITKAQHLIATMAYQYTDVPLTEEVARLNPLGFQVMRYDLAADLSR 228 TG+ + +AT+ Y+ P E NPLG+QV Y ++ + Sbjct: 180 ---TGSNSTKTDAVATIKYKVDGTPSKEVDRFKNPLGYQVESYRADVEVPQ 227
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 31.5 bits (71), Expect = 0.002 Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 14/65 (21%) Query: 142 AQAAQKAAIERSLQAVSANMNWQAYTRSGDAAIAPVHAWDDGRQTWLQFAPQADIPTVYR 201 AQ A + IE + V A QA +GD A A + WL D P + Sbjct: 34 AQMAGQLGIEATGSGVCAGPAEQANALAGDVACA---------EQWL-----GDKPVSWS 79 Query: 202 VTPDG 206 TPDG Sbjct: 80 PTPDG 84
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.1 bits (83), Expect = 1e-04 Identities = 12/85 (14%), Positives = 22/85 (25%) Query: 69 PAAKADSGLEADQSGITNRLKAPEVERPAPPPALPPPTPEPTVAPNYNVPSPMPAAPPPV 128 P + E + + +E+P P P P + P +V P Sbjct: 70 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPF 129 Query: 129 DELTQRRLASPLQAGGADASGATPS 153 + R S + + Sbjct: 130 ENTAPARPTSSTATAATSKPVTSVA 154 Score = 35.7 bits (82), Expect = 2e-04 Identities = 22/132 (16%), Positives = 41/132 (31%), Gaps = 6/132 (4%) Query: 43 RAFLW---LTILIAVAVAAGVLMKVWSREPAAKADSGLEADQSGITNRLKAPEVERPAPP 99 R F W L++ I AV AG+L + A + + + + PP Sbjct: 12 RRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPA--QPISVTMVAPADLEPPQAVQPP 69 Query: 100 PA-LPPPTPEPTVAPNYNVPSPMPAAPPPVDELTQRRLASPLQAGGADASGATPSQSNGP 158 P + P PEP P +P+ P + + ++ D ++ Sbjct: 70 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPF 129 Query: 159 QGPYSDAGPLAD 170 + + Sbjct: 130 ENTAPARPTSST 141
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.038 Identities = 11/33 (33%), Positives = 19/33 (57%) Query: 128 ANENLHLLITGATGSGKSVLLRNMAASVLRRSR 160 +L L+ITG +G+GK ++ R + RR+ Sbjct: 157 MQTDLTLMITGESGTGKELVARALHDYGKRRNG 189
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 65.1 bits (158), Expect = 2e-14 Identities = 60/245 (24%), Positives = 101/245 (41%), Gaps = 19/245 (7%) Query: 3 LKGEVALVTGGGAGLGRAIVDRYVAEGARVAVLDKSAAGLEEIRK------RHGDAVVGI 56 ++G++A +TG G+G A+ ++GA +A +D + LE++ RH +A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA---F 62 Query: 57 EGDVRSLDSHREAVARCVETFGKLDCLIGNAGVWDYLTQLADIPDNGISEAFDEMFAINV 116 DVR + E AR G +D L+ AGV + + D E ++ F++N Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSD----EEWEATFSVNS 117 Query: 117 KGYILAAKAALPALYKSKGSAIFTV-SNAGFYPGGGGVLYTAGKHAVIGLVKQLAHEWGP 175 G A+++ + + +I TV SN P Y + K A + K L E Sbjct: 118 TGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 176 R-IRVNGIAPGGILGSDLRGLKT-LGLQDQTIATMPLADMLGPVLPTGRVATAEEYAGAY 233 IR N ++PG L +Q I G +P ++A + A A Sbjct: 178 YNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTG--IPLKKLAKPSDIADAV 235 Query: 234 VFFAT 238 +F + Sbjct: 236 LFLVS 240
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 9e-04 Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 7/95 (7%) Query: 110 LGAIIFGRFGDKIGRKTTFLITIVMIGSATVGMGLLPTFASIGWWAPILLTLLRVMQGLA 169 +G ++G+ D++G K L I++ +V + +F S+ L + R +QG Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL-------LIMARFIQGAG 116 Query: 170 LGGEYGGAAAYVAEYSEPKRRGLTTGFLQATAALA 204 VA Y + RG G + + A+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMG 151
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.045 Identities = 11/22 (50%), Positives = 14/22 (63%) Query: 36 VVTLLGRNGMGKTTTIRSLVGA 57 V L G G+GK+T I +LVG Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.045 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 1/33 (3%) Query: 50 MIHGEPGTGKSVVMRVLAEKLERLTDLTVVSIN 82 MI GE GTGK +V R L + +R + V+IN Sbjct: 164 MITGESGTGKELVARALHDYGKR-RNGPFVAIN 195
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.004 Identities = 22/176 (12%), Positives = 62/176 (35%), Gaps = 5/176 (2%) Query: 76 NTQLVQQVADLQERLAAEERHRQSLEEKHKHARQALEHFRESTKEQRDQDQRKHEQQVQY 135 ++ + L + + R++ + L+ E + +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTS--L 190 Query: 136 LQAELRTVNETLATKQQEAVHTLQENARLLGDLSRAQGDLHQAQEEVRGLRPLKDELGFA 195 ++ + T K+ E +L ++R + + + L + A Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 196 QRRSEELGRRLVEQDAAVQQLSTSKEQLQAKVDELLSAKQQLELALATARSSVTAQ 251 + E + VE ++ + EQ+++ E+LSAK++ +L ++ + + Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIES---EILSAKEEYQLVTQLFKNEILDK 303
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (340), Expect = 6e-41 Identities = 85/252 (33%), Positives = 124/252 (49%), Gaps = 11/252 (4%) Query: 5 IRGKVALVTGSGRGIGAEASRQLAQEGARVVICDIDVETADATAQNLRDEGFEAMAIQCD 64 I GK+A +TG+ +GIG +R LA +GA + D + E + +L+ E A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 VCDKDQVQAGIDAVVKEWGGVDILVNNAGFTRDKYLTKMSEEDWDSVVDTILKGAFHFSR 124 V D + + +E G +DILVN AG R + +S+E+W++ G F+ SR Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 125 AVLPGMMERKWGRIVNIASRSVFGNP--GQTNYTTAKLGLVGFTRALALEQARFGITVNA 182 +V MM+R+ G IV + S G P Y ++K V FT+ L LE A + I N Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 183 IAPGFIETELMRSLPTYPELREMALARN--------PVGFLGAPEDIASSVAFLSSEHAR 234 ++PG ET++ SL E + + P+ L P DIA +V FL S A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 235 YITGITLYVTGG 246 +IT L V GG Sbjct: 245 HITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.1 bits (140), Expect = 8e-13 Identities = 29/171 (16%), Positives = 57/171 (33%), Gaps = 8/171 (4%) Query: 6 TREQLVCHAQALIRQRGYNGFSYRDLAERVGVKTASIHYYFPCKDDLLIEAIDSYAQHVA 65 TR+ ++ A L Q+G + S ++A+ GV +I+++F K DL E + ++ Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 66 GLVHGIDATLPA------KERLDRY-AALFEGGPTDQVCLCGMLAADFASLSDRARKSLQ 118 L A P +E L + + +F +++ + Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 119 GFFCLHETWLAKVIADGQRDGTLQWAGCPDAAGRCLFAAFQGALMGSRLFQ 169 + + + L A + G LM + LF Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG-LMENWLFA 181
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 8e-09 Identities = 65/337 (19%), Positives = 118/337 (35%), Gaps = 29/337 (8%) Query: 43 AFQFGLLTSTPVLTGAVFRLPLGMWTDRYGGRAVMTVLLVGCAIPVYLVSYAQALWQFLL 102 +G+L + L LG +DR+G R V+ V L G A+ +++ A LW + Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYI 101 Query: 103 IGLFLGLVGASFAVGTPYVARFFSAERKGFAMGFFGAGTVGAAVNLFVTPILLETYGWRA 162 + G+ GA+ AV Y+A + + GF A V V L+ + A Sbjct: 102 GRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHA 161 Query: 163 VPKIYAVALLVTAALFWFVAAPDPGAGKAGGKLLDQFKILKN--------PRVWRYCQYY 214 P A AL L P+ G+ + L + ++ Sbjct: 162 -PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF 220 Query: 215 SITFGGFTALSLWIPQYFQAEYGLSLVAASALAAGFSLPGAVLRA-VGGSLADRYGAHKM 273 + G +LW+ + + + A F + ++ +A + G +A R G + Sbjct: 221 IMQLVGQVPAALWV-IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRA 279 Query: 274 TWWCLWLAWICLFILSYPNTTLTVQTLNGSAAFHIYLPIWLFTLLLFVLGAMFAFGMAST 333 + +A +IL AF + ++L G + + + Sbjct: 280 LMLGM-IADGTGYILL---------------AFATRGWMAFPIMVLLASGGIGMPALQAM 323 Query: 334 FKYVADDFPENMGVVTGIVGLAGGLGGFLLPLMFGAM 370 D+ E G + G + L + PL+F A+ Sbjct: 324 LSRQVDE--ERQGQLQGSLAALTSLTSIVGPLLFTAI 358
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.1 bits (169), Expect = 5e-17 Identities = 20/110 (18%), Positives = 46/110 (41%), Gaps = 6/110 (5%) Query: 7 VAIVDDDESIRHATDSLVRSFRR---RTLVFASAEDFLQSGKLAETSCLISDIMMPGMSG 63 + + DDD +IR L ++ R + ++A + + +++D++MP + Sbjct: 6 ILVADDDAAIR---TVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 LEMHKRMRMLGYAPPTIFITAYPAADLTAQAMASGALAVLEKPVEADAIA 113 ++ R++ P + ++A +A GA L KP + + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 111 bits (278), Expect = 1e-30 Identities = 32/148 (21%), Positives = 64/148 (43%) Query: 21 VYIVDDDESMRLSLQSLLRSSGLRVETFQSAQEFLAFPKSQGPSCLVLDVRLRGESGLAF 80 + + DDD ++R L L +G V +A + + +V DV + E+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 81 QEQIAKSGLRMPIVFMTGHGDIAMTVKAMKAGAVDFLAKPFRDQDMLDAVANALARDSER 140 +I K+ +P++ M+ +KA + GA D+L KPF +++ + ALA R Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 141 LAAEQSIAQLRAAHASLTPREREVMALV 168 + + +Q + +E+ ++ Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.4 bits (73), Expect = 0.022 Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 24/179 (13%) Query: 112 DKLHQHGLIHKDIKPAHILVHCTDGRARFTGFGLASRLPRERQAPTPPETIAGTLAYMAP 171 + L + G++H DIKP +++ G GL SR + + T ++ AP Sbjct: 259 NHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTE--------SFKAP 310 Query: 172 EQTGRMNRSVDSRSDLYALGVTFYQMLTG------VLPFSAMDAMEWVHCHIARTPMPAA 225 E G N +SD++ + T + G + P + + H+ Sbjct: 311 E-LGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPI 369 Query: 226 ER--VATVPAAISRIVMKLLAKTAEDRYQTAAGLEHDLRRCLADWNRLGRIDEFSLDEL 282 R +A V A +R + +L +A+ R + H+ L+D G IDE S ++ Sbjct: 370 HRPGIAGVETAYTRFITDILGVSADSRPDSNEARLHEF---LSD----GTIDEESAKQI 421
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (312), Expect = 1e-36 Identities = 76/253 (30%), Positives = 118/253 (46%), Gaps = 14/253 (5%) Query: 5 LEGKTAFVTAAGQGIGRATALAFAREGATVLAADLNPQALGGLGECKPVT--------LD 56 +EGK AF+T A QGIG A A A +GA + A D NP+ L + D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 57 VTDAAAV----ARAVEVAGPVDILFNGAGFVHAGTILDCDDAAWDFSFDLNVRAMYRLIR 112 V D+AA+ AR GP+DIL N AG + G I D W+ +F +N ++ R Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 113 AFLPGMLARGGGSIINMASAASSVKGVPNRFVYGTTKAAVIGLTKSVAADFVGRGIRCNA 172 + M+ R GSI+ + S + V + Y ++KAA + TK + + IRCN Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRT-SMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 173 ICPGTVESPSLRQRIAEQARASGQTEQAVEAAFVARQPMGRIGRAEEIAALALYLASDES 232 + PG+ E+ A++ + Q + F P+ ++ + +IA L+L S ++ Sbjct: 185 VSPGSTETDMQWSLWADE-NGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 233 AFTTGTAQIIDGG 245 T +DGG Sbjct: 244 GHITMHNLCVDGG 256
>FLAGELLIN#Flagellin signature. Length = 507 Score = 37.3 bits (86), Expect = 8e-04 Identities = 32/279 (11%), Positives = 68/279 (24%), Gaps = 6/279 (2%) Query: 1490 AQSIGGGGGLAGAGSANNLTSVTLGGRNGATGDGGAVSLALNAGSVISTTGAGAH--ALV 1547 +S+G G + + +N D AV V S V Sbjct: 164 VKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTV 223 Query: 1548 AQSIGGGGGIAGDTAQAVQLDASHWQPSGTNSGGSAVTGGSGNGSAVTVDVNGSIVTSGA 1607 + T + + + T S + G+ + G Sbjct: 224 PDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGV 283 Query: 1608 GAFGILAQSIGGGGGLGGGLVPDGAGDGGTISQGFAGSTGGSGSGAEVTVTQAGSIVVAG 1667 G G + + +G T++ AG+ + + + S+V Sbjct: 284 TFTIDTKTGNDGNGKVSTTI--NGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQ 341 Query: 1668 AGSTGIFAQSAGGDGAGAVTVNVNGSVTGGSGSSGYGVWVASPAQNVLNVGADGQIIAGQ 1727 + V G + Y A + A Sbjct: 342 FTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASG 401 Query: 1728 GGAAVRHDGAALSGAGAALAPAGAATLAINNAGSIRGNI 1766 + + A + + P + A++ ++R ++ Sbjct: 402 VSTLI--NEDAAAAKKSTANPLASIDSALSKVDAVRSSL 438
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 40.3 bits (94), Expect = 6e-06 Identities = 17/83 (20%), Positives = 32/83 (38%), Gaps = 1/83 (1%) Query: 445 ATLEAANQAQPDTVEIKYELAMLYERQGRYDELETQLRQVIALDPDHAHAYNALGYTLAD 504 T+ N+ DT+E Y LA + G+Y++ + + LD + + LG Sbjct: 23 GTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82 Query: 505 RNQRLPEALDLITQALELQPDDP 527 Q A+ + + +P Sbjct: 83 MGQ-YDLAIHSYSYGAIMDIKEP 104
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 28.6 bits (64), Expect = 0.030 Identities = 19/81 (23%), Positives = 32/81 (39%), Gaps = 12/81 (14%) Query: 17 PSLSATARALNVTPPALSMRLRKLEAALG-----LALAVRTARRLSLTPEGERFAR---- 67 SL AT P +++ E+ L + + + + R L+ ERF Sbjct: 9 ISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTF 68 Query: 68 ---EAAALLAQLQALPESLQR 85 A+LA++ A E L+R Sbjct: 69 KVVLCGAVLARVDAGDEQLER 89
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 42.8 bits (101), Expect = 1e-06 Identities = 32/188 (17%), Positives = 62/188 (32%), Gaps = 18/188 (9%) Query: 16 AIIDVARMQANIDRMQQRMNTLGVALRPHVKTSK----CTPVAQAQLAAGARGITVSTLK 71 A +D+ ++ N+ ++Q + VK + + A A + L+ Sbjct: 7 ASLDLQALKQNLSIVRQAA--THARVWSVVKANAYGHGIERIWSAIGATDGFA--LLNLE 62 Query: 72 EAEQFFEAGI-ADILYAVGMV-PQRLPAALALRRRGCDLKIITDNAAAARAIAAFGREHG 129 EA E G IL G Q L R + ++ A A Sbjct: 63 EAITLRERGWKGPILMLEGFFHAQDLEIYDQHR---LTTCVHSNWQLKALQNARLKA--- 116 Query: 130 EVFEVWIEIDTDGHRSGIKPGEAALLEVGAALHEGGMTLGGVMTHAGSSYDLDTPAALAA 189 ++++++++ +R G +P L + +M+H + D + A Sbjct: 117 -PLDIYLKVNSGMNRLGFQPDR-VLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMA 174 Query: 190 MAEQERAG 197 EQ G Sbjct: 175 RIEQAAEG 182
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.9 bits (67), Expect = 0.013 Identities = 26/166 (15%), Positives = 47/166 (28%), Gaps = 27/166 (16%) Query: 24 ISAVARRLDLSQPAVSNALRRLRATLGDDLFVRTPQGMQPTPQAERLGGPVGEALALLSH 83 I+ A R SQ + L R+ +L P + + V AL L+ Sbjct: 477 INDPASRSRRSQSDLPRRLNRVILSL--------PTAT-SVQEQAMIRSRVSGALTLVKE 527 Query: 84 TLEATQDFHPADSQRRFRIAMS-DVGEIHFMPRLMEQCARHAPAIRIDSLRLAGADLRRE 142 L + + + + D + L + RID+ R + Sbjct: 528 MLGTKDGTSTIAVEGKPELLVDWDEASCTQLVYLYSE-LTQKFDGRIDTFLDLKGQPRPD 586 Query: 143 MDAGRV---------------DLAIGAFEDLGS-GIMQRMLFRQGY 172 G DL + + + + FR+G+ Sbjct: 587 PAGGESPSLRLACIDVGGGTTDLMVTTYRGEDNRVLHPEQTFREGF 632
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 5e-20 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 4/138 (2%) Query: 9 RYRVLVVEDDLTIAGNLYRFLEVNGFVPDVAYDGRTALRMLQDQRFDAMVLDVGLPGLDG 68 +LV +DD I L + L G+ + + T R + D +V DV +P + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 69 YQVLQTLRAERRQAIPVLILTARDALDDKLEGFSHGADDYLTKPFALAEVQA---RLLAL 125 + +L ++ + R +PVL+++A++ ++ GA DYL KPF L E+ R LA Sbjct: 63 FDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 126 IHRAQGAVVDAVREFGPL 143 R + D ++ PL Sbjct: 122 PKRRPSKLEDDSQDGMPL 139
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 691 bits (1786), Expect = 0.0 Identities = 282/855 (32%), Positives = 426/855 (49%), Gaps = 45/855 (5%) Query: 1 MAACSALSIAQEQGGDAAMFDESFLYRAPGQAGGVDLSVFAYSSRVLPGSKSVLLQLNER 60 + A + F+ FL P DLS F + PG+ V + LN Sbjct: 30 LFVACAFAAQAPLSSAELYFNPRFLADDPQ--AVADLSRFENGQELPPGTYRVDIYLNNG 87 Query: 61 AIGNRVVEFIVVPGKEDAQPCYSVAALRELGVKVEAFPELQKMDENECGRALEIIPSAKA 120 + R V F ++ PC + A L +G+ + + + ++ C +I A A Sbjct: 88 YMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATA 147 Query: 121 SYDQDANILRLSIPQAALGRQARGVVPVERWDSGTTALWSSYRMSYNHMRSTGGPGSYSN 180 D L L+IPQA + +ARG +P E WD G A +Y S N +++ ++ Sbjct: 148 QLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN---RIGGNS 204 Query: 181 DTLYLGFRNGLNLGAWRIRGNGSY------YENGYSTDWDWSDLYAERDIVSWRGRLRLG 234 YL ++GLN+GAWR+R N ++ +G W + + ERDI+ R RL LG Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 235 DSATEGRIFDSVRFRGIQLRSDDGMLPDSQRGYAPVIRGIAPSNAKVTVRQNGYVLYTTF 294 D T+G IFD + FRG QL SDD MLPDSQRG+APVI GIA A+VT++QNGY +Y + Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 295 VPAGPFVIDDLYSTPGGGDLEVEIDEMGGRTTRYFQPFSALPTMMREGIWNYNFMVGEHR 354 VP GPF I+D+Y+ GDL+V I E G T + P+S++P + REG Y+ GE+R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 355 HNYD-TSRPLMGQLTLAYGLPWGLTAYGGWTLAQHGYHAGAFGLAANLRHLGAVSADITS 413 +P Q TL +GLP G T YGG LA Y A FG+ N+ LGA+S D+T Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVDMTQ 443 Query: 414 SRSRDVRGNSMSGSAVSVQYAKSFPGSGTDFTLASYRYNSSGYRSLNDVVRDRAEQYD-- 471 + S + G +V Y KS SGT+ L YRY++SGY + D R Y+ Sbjct: 444 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 503 Query: 472 ----------------YIGYDREHEYQLSMQQRLGRMGSLSFNYYGIAYRNAPRNARYAQ 515 + Y++ + QL++ Q+LGR +L + Y Q Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQ 563 Query: 516 VGYSSSLGRLGYSLNYALSRSPWNAREST-LMLTLSIPLGGSH-----------TASYAM 563 G +++ + ++L+Y+L+++ W L L ++IP +ASY+M Sbjct: 564 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM 623 Query: 564 NRTDNQGTNHSVSLSGAMLDDYSLTYALQAGVTRGEGQDNGNTGYGSLGYSSPVGLATVS 623 + N + + G +L+D +L+Y++Q G G ++G+TGY +L Y G A + Sbjct: 624 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG 683 Query: 624 HAYSRNSSNTYLDISGSILADSKGVLFGQSLGETAVIVEAPGAAGVAIDALPGVRTNSAG 683 +++S + Y +SG +LA + GV GQ L +T V+V+APGA ++ GVRT+ G Sbjct: 684 YSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRG 743 Query: 684 RALVPYASPYRENRISLDAGEGLDGAHLKQNVQTVVPTRGAIVVAKFDTEIGRTVLAVLK 743 A++PYA+ YRENR++LD D L V VVPTRGAIV A+F +G +L L Sbjct: 744 YAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT 803 Query: 744 DGSGRVVPFGAAVHGDDGRQRGIVGPVGRAWLTGLQGMQRFTAKWGEQGDQQCSFEIDVS 803 + + +PFGA V + + GIV G+ +L+G+ + KWGE+ + C + Sbjct: 804 H-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLP 862 Query: 804 ADQDAAG-QAKELIC 817 + C Sbjct: 863 PESQQQLLTQLSAEC 877
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 29.9 bits (67), Expect = 0.007 Identities = 14/42 (33%), Positives = 22/42 (52%) Query: 50 GLEYDPELLYLGAMFHDMGLTQPYASTDLRFEVDGANAARDF 91 GL+YD +YL M+ + PY TD ++ AN ++F Sbjct: 251 GLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNF 292
>PF07132#Harpin protein (HrpN) Length = 356 Score = 32.0 bits (72), Expect = 0.006 Identities = 16/43 (37%), Positives = 19/43 (44%) Query: 450 GMVALAKLQKSSSSSSGGSGSSGGGSSGGSFGGGSSGGGGAGG 492 M + + GG GSS GG GG GGG GG G+ Sbjct: 58 MMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSL 100 Score = 30.4 bits (68), Expect = 0.015 Identities = 14/33 (42%), Positives = 15/33 (45%) Query: 460 SSSSSSGGSGSSGGGSSGGSFGGGSSGGGGAGG 492 GG GSS G G + GGG G GAG Sbjct: 88 LGGGLGGGLGSSLGSGLGSALGGGLGGALGAGM 120
>cloacin#Cloacin signature. Length = 551 Score = 33.9 bits (77), Expect = 0.003 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 8/86 (9%) Query: 51 GSGGAGGGDGTDGYISGGNGGSDFFLPGAGGAAGVPLPTQTIP-GTADGSSLLPSYEYVG 109 G G G T G I+GG G G G + G ++ P G GS + + G Sbjct: 6 GRGHNTGAHSTSGNINGGPTGLG---VGGGASDGSGWSSENNPWGGGSGSGI----HWGG 58 Query: 110 IGGGGGGGDGGDLGGLHGEVGGAGAI 135 G G GG G+ GG G G A+ Sbjct: 59 GSGHGNGGGNGNSGGGSGTGGNLSAV 84 Score = 33.1 bits (75), Expect = 0.005 Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 11/117 (9%) Query: 52 SGGAGGGDGTDGYISGGN--GGSDFFLPGAGGAAGVPLPTQTIP-GTADGSSLLPSYEYV 108 SGG G G T + + GN GG G G + G ++ P G GS + Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSG-------I 54 Query: 109 GIGGGGGGGDGGDLGGLHGEVGGAGAINLDGTALNVD-NTLFVGGAGGGGGSGGAGS 164 GGG G G+GG G G G G ++ + L GAGG S AG+ Sbjct: 55 HWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGA 111 Score = 33.1 bits (75), Expect = 0.006 Identities = 28/97 (28%), Positives = 37/97 (38%), Gaps = 4/97 (4%) Query: 157 GGSGGAGSTRGGTGGAGGAGTLTATGGATITVGTQLYIGGLPGAGGNCGCSGNGGAGGAG 216 GG G G G + G+G + GG + G G G GG G SG G G Sbjct: 22 GGPTGLGVGGGASDGSGWSSENNPWGGGS-GSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Query: 217 VFNLGDGSTLNLTGAAFTINGAGTLNIGSATANETSA 253 + + A + GAG L + S +A SA Sbjct: 81 LSAVAAPVAFGF--PALSTPGAGGLAV-SISAGALSA 114 Score = 32.4 bits (73), Expect = 0.009 Identities = 19/67 (28%), Positives = 22/67 (32%), Gaps = 9/67 (13%) Query: 109 GIGGGGGGGDGGDLGGLHGEVGGAGAINLDGTALNVDNTLFVGGAGGGGGSGGAGSTRGG 168 G+G GGG DG + GG + G G GG G G Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIH---------WGGGSGHGNGGGNGNSGGGSG 76 Query: 169 TGGAGGA 175 TGG A Sbjct: 77 TGGNLSA 83
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.0 bits (72), Expect = 0.008 Identities = 16/52 (30%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 435 AGATGMLS--VGTTCAGAGIIVGVVTLTGLGLKFSGIVIDYAGGSLLLTAIY 484 A + + + + AG++ GV L LG KFS + Y G +LL +Y Sbjct: 48 ARSLEKVPVKFTASVSRAGVLAGVGKLARLGAKFSTRAVPYVGTALLAHDVY 99
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.6 bits (193), Expect = 2e-19 Identities = 63/280 (22%), Positives = 104/280 (37%), Gaps = 50/280 (17%) Query: 4 GIRGRHALVFGGSKGMGRACAHQLASEGVNVTIA----------ARTESTLAKAADEITA 53 GI G+ A + G ++G+G A A LAS+G ++ + A+ A+ A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 54 --ATGTRVRYVVADITTDEGRGAALSACATPDILVNNADGAPPGDFRQWTQADWHSALDS 111 + + A I + G DILVN A PG + +W + Sbjct: 65 DVRDSAAIDEITARIEREMGP---------IDILVNVAGVLRPGLIHSLSDEEWEATFSV 115 Query: 112 MALGPIDMIRRVVDGMMERRFGRIVNIVSRSVKAPQLELGLSNGARSCLVGFVAGLARQT 171 + G + R V MM+RR G IV + S P+ + +++ V F L + Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 172 VRHNVTINNLLPGVFATDAQRHHIEGMLEPGGKTFEQLWTERGANN-------------- 217 +N+ N + PG TD Q LW + Sbjct: 176 AEYNIRCNIVSPGSTETDMQW---------------SLWADENGAEQVIKGSLETFKTGI 220 Query: 218 PAGRYGEPEELGALCAYICAAQAGYICGQNILIDGAAYPG 257 P + +P ++ ++ + QAG+I N+ +DG A G Sbjct: 221 PLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLG 260
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 95.1 bits (236), Expect = 2e-26 Identities = 52/209 (24%), Positives = 82/209 (39%), Gaps = 5/209 (2%) Query: 1 MAGQRKIDALETRERILDAAEWCFCAYGVSHASLEAIAEKASCTRGAIYWHFSGHADLIK 60 MA + K +A ETR+ ILD A F GVS SL IA+ A TRGAIYWHF +DL Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 GIMERGLPPYTKRLEALSYA-PSPLIQKIRECLQECFAAIDGDQHVRNALTILLLRNDFL 119 I E + P + +RE L + ++ R + I+ + +F+ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 120 GLREPFLDSRYQESIEVTAPLALAFRRAISNGEMSSALDPEICAEMINSTMLGILRRSLL 179 G ++ +E + + I + + L A ++ + G++ L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 180 R-NSCVLAGTGADVLEMAFALIAGISHRP 207 S L D + L+ P Sbjct: 181 APQSFDLKKEARDYVA---ILLEMYLLCP 206
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.9 bits (142), Expect = 8e-13 Identities = 36/165 (21%), Positives = 55/165 (33%), Gaps = 3/165 (1%) Query: 14 TPEEILDAAEWCFLHLGVAGTSTALIAARTRCARSLVSAHFPSPRSILQEVLYRGRLPLI 73 T + ILD A F GV+ TS IA R + HF + E+ + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 74 GHLRRVKATQT-QLIPALRSALQLCLNDILHNERVRATQEILLFHCDLRHLPKDVLEQQI 132 +A + LR L L + ER R EI +FH V++Q Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEI-IFHKCEFVGEMAVVQQAQ 130 Query: 133 KESAEAM-ALLRSIAVDAKRAGELRENICPESWASILGQLLSGAV 176 + + A L ++ A I+ +SG + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1197 bits (3098), Expect = 0.0 Identities = 605/1032 (58%), Positives = 789/1032 (76%), Gaps = 6/1032 (0%) Query: 1 MSRFFIDRPIFAWVVAIVIMLAGALSILSLPVNQYPNIAPPAIGIIANYPGASAQTVQDT 60 M+ FFI RPIFAWV+AI++M+AGAL+IL LPV QYP IAPPA+ + ANYPGA AQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQQLNGLDGLRYIRSESNADGSVTIVVTFEQGVNPDIAQVQVQNKLSLATPMLPQ 120 VTQVIEQ +NG+D L Y+ S S++ GSVTI +TF+ G +PDIAQVQVQNKL LATP+LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQQLGLRVVKYQVNFMLVAALISEDGRLDNYALADQIVSQLQDPLTRTAGVGDFFVMGS 180 VQQ G+ V K ++++VA +S++ ++D + S ++D L+R GVGD + G+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QNAMRVWLDPLKLNNYALTPGDVIAAIEEQNVQVSSGQLGGRPTAGKVELNATVIGKTLL 240 Q AMR+WLD LN Y LTP DVI ++ QN Q+++GQLGG P +LNA++I +T Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEQFGAMLLKVNTDGSQVRLRDVADVALGADNFSITTRYNGKPSAGIALRLASGGNTL 300 + PE+FG + L+VN+DGS VRL+DVA V LG +N+++ R NGKP+AG+ ++LA+G N L Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 EAVKAVQETLSRLEPTLPPGVKVVYPYNTAPVVSESINGVVHTLLEAIVLVFVIMYLFLQ 360 + KA++ L+ L+P P G+KV+YPY+T P V SI+ VV TL EAI+LVF++MYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NWRATLIPTLAVPVVLLGTFGVMAAVGFTINTLTMFGLVLAIGLLVDDAIVVVENVERLM 420 N RATLIPT+AVPVVLLGTF ++AA G++INTLTMFG+VLAIGLLVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 VEEGLSPLEATRKSMEQISGALVGIGLVLSAVFIPMAFFGGSTGVIYRQFSLTIVTAMTL 480 +E+ L P EAT KSM QI GALVGI +VLSAVFIPMAFFGGSTG IYRQFS+TIV+AM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVFVALIFTPALCATMLKPVHGHH--EKKGFFGWFNRMFERNAQRYESGVTRVVAGRGRY 538 SV VALI TPALCAT+LKPV H K GFFGWFN F+ + Y + V +++ GRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 539 MLAFALIVGALAVLFPMMPTSFLPDEDQGTMVVQVELPTNSTADQTDQLLNELSTYLLEE 598 +L +ALIV + VLF +P+SFLP+EDQG + ++LP +T ++T ++L++++ Y L+ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 599 EGDVVDSVFAVNGFSFAGRGQNSGLAFVQLKPWEERKR---SVFDLQASAMQRFSEVKAG 655 E V+SVF VNGFSF+G+ QN+G+AFV LKPWEER S + A +++ G Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 656 TALAFAPPAIQELGNATGFNLFLQDYRGEGHEQLMQVRGQFLAEASKHPA-LTLVRPNGK 714 + F PAI ELG ATGF+ L D G GH+ L Q R Q L A++HPA L VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 715 PDEPQYQVIIDDEKARALGVTLAEVNRTMSTAWGSSYVNDFIDRGRVKRVYVQGIPQARI 774 D Q+++ +D EKA+ALGV+L+++N+T+STA G +YVNDFIDRGRVK++YVQ + R+ Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 775 TPEDFNKWYVRNKNGQMVSFASFATGKWVYGSPKLERYNGVPAIEILGEPAPGYSSGDAM 834 PED +K YVR+ NG+MV F++F T WVYGSP+LERYNG+P++EI GE APG SSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 835 RAVEEIAAKLPSGVSLAWTGLSYEERLSGSQAPALYALSIVAVFLCLAALYESWSIPFSV 894 +E +A+KLP+G+ WTG+SY+ERLSG+QAPAL A+S V VFLCLAALYESWSIP SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 895 LLVVPLGVIGTVAATLMRGLENDAFFQIGLLTTVGLCAKNAILIVEFAKDLHEKGGRTLV 954 +LVVPLG++G + A + +ND +F +GLLTT+GL AKNAILIVEFAKDL EK G+ +V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 955 QAAIEASRLRLRPIIMTSLAFTMGVIPLAISSGASSGSKHAIGTGVIGGMVTATFLAIFF 1014 +A + A R+RLRPI+MTSLAF +GV+PLAIS+GA SG+++A+G GV+GGMV+AT LAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1015 IPLFYVVVSSLF 1026 +P+F+VV+ F Sbjct: 1021 VPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.8 bits (106), Expect = 3e-07 Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 2/93 (2%) Query: 73 EVRPQVTGILLERQFQEGSEVKAGQVLYQINPAPFRATLSRAQASLDSAKLLADRYDRLI 132 E++P I+ E +EG V+ G VL ++ A + Q+SL A+L RY L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 133 ETRAISQQERDDARSQ--YLQARAAVESARIDL 163 + +++ + + L Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Score = 37.1 bits (86), Expect = 9e-05 Identities = 14/86 (16%), Positives = 33/86 (38%), Gaps = 3/86 (3%) Query: 108 RATLSRAQASLDSAKLLADRYDRLIETRAISQQERDDARSQYLQARAAVESARIDLDFTR 167 ++ L + ++ + SAK +L + + + + + Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLFKNEILDK--LRQTTDNIGLLTLELAKNEERQQASV 329 Query: 168 ITAPISGRIGRSSV-TQGALVTANQA 192 I AP+S ++ + V T+G +VT + Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAET 355
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.8 bits (134), Expect = 6e-12 Identities = 27/181 (14%), Positives = 58/181 (32%), Gaps = 11/181 (6%) Query: 13 AKRRKEQVITAAAECVRREGFHRTSMSQISAAAGMSAGHIHHFFGGKDGIIAGIVAREHT 72 A+ ++ ++ A ++G TS+ +I+ AAG++ G I+ F K + + I + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 73 ELAQLIEDV--RSSSQGSDAVTAIVKELPRSVPRYMDPGRAALTMEILAEASR-NSEVAH 129 + +L + + + I+ + S + E + V Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 130 LIQENDVEVRHAFRDLLGN--------RASDIEARCEIVGALLEGLSARTLRNPQLSTMV 181 + +E L + I+ + GL L PQ + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 182 N 182 Sbjct: 189 K 189
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 27.0 bits (59), Expect = 0.045 Identities = 14/36 (38%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 22 STVYAQEVPPPAYQLAAQRAGIPSTVLYAVALQESG 57 S + ++ PA QLA+Q++G+P ++ A A ESG Sbjct: 149 SKAFLAQLSLPA-QLASQQSGVPHHLILAQAALESG 183
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 7e-04 Identities = 15/48 (31%), Positives = 21/48 (43%), Gaps = 6/48 (12%) Query: 376 MLFLVGENGSGKTTLIKLLLGLYEPQEGMILLDGAPVVAQNRDDYRQL 423 + L G G GK+TLI L+GL D + +D Y Q+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD------FFSDTHFDIGTGKDSYEQI 639
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 147 bits (371), Expect = 5e-44 Identities = 88/304 (28%), Positives = 136/304 (44%), Gaps = 15/304 (4%) Query: 27 VPALERRRFCLGGVAYLAWAGTVPLGALARTDSAQTLGTRGARIACTDWAAAESLALLGC 86 +P + RRR L PL T A + RI +W E L LG Sbjct: 4 LPLISRRRL-------LTAMALSPLLWQMNTAHAAAIDPN--RIVALEWLPVELLLALGI 54 Query: 87 MPIAVPELAVYRLWLPEPPLPANVADLGSRSEPNLELLAALAPERIVVSSWQAGLLGQFG 146 +P V + YRLW+ EPPLP +V D+G R+EPNLELL + P +V S+ Sbjct: 55 VPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLA 114 Query: 147 RIAPTEVAHIFDGCADPYLRIRELLLQMGTATGLEAQAQMRLREFDTEIECLRAQLAAGA 206 RIAP + DG P R+ L +M L++ A+ L +++ I ++ + Sbjct: 115 RIAPGRGFNFSDG-KQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFV--K 171 Query: 207 DAARSVYMAVLHENGAQAFVYGQGSWVNRVLGQLGLRNAWSARTTFYGNSLVGIAALAAE 266 AR + + L + V+G S +L + G+ NAW T F+G++ V I LAA Sbjct: 172 RGARPLLLTTLID-PRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAY 230 Query: 267 PEAVILYLDQGARTRRAEALLRDSTLWRSLPAVASGRAHAIASFYALGGLASAQRCARLV 326 + +L D L + LW+++P V +GR + + + G SA R++ Sbjct: 231 KDVDVLCFDHDNSKDMDA--LMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVL 288 Query: 327 VGAL 330 A+ Sbjct: 289 DNAI 292
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 31.8 bits (72), Expect = 0.003 Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARSLAADGFPVQQSHISRMAD---AVR---------YLLPA 201 +Q EL L DG+ V Q+ +SR V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.2 bits (135), Expect = 5e-12 Identities = 28/144 (19%), Positives = 53/144 (36%), Gaps = 11/144 (7%) Query: 22 HTVLQAARKVFLTHGFSATT-DMIQQMAGVSKSTVYAHYANKETLFSAVIEAECQSFSDK 80 +L A ++F G S+T+ I + AGV++ +Y H+ +K LFS + E S S+ Sbjct: 14 QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE---LSESNI 70 Query: 81 VSAIRFQSGKLKDTLAALGSAYLDIVLT-----PEKLALYRIVIAEAPRFPRLA--HKFY 133 K ++ L VL + L I+ + +A + Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 134 EAGPNAVVSIVARYLDIAVTSREL 157 + + L + ++ L Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKML 154
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 4e-14 Identities = 27/128 (21%), Positives = 46/128 (35%), Gaps = 7/128 (5%) Query: 2 RRAAIQQAALDVFSECGYTRATMREIARRAGVTHGLVQRHFGSKEALFLATVPGT----R 57 R I AL +FS+ G + ++ EIA+ AGVT G + HF K LF + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 58 DWESVIIQEGKGSLAERIAAAFTDRGEA---GTGLDALVALLRSTASDIGAAKKLYGVMR 114 + E + G + E+ L+ ++ +G + R Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 115 DGGAALYE 122 + Y+ Sbjct: 132 NLCLESYD 139
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.7 bits (129), Expect = 5e-10 Identities = 39/185 (21%), Positives = 71/185 (38%), Gaps = 6/185 (3%) Query: 18 RLLATLSLLLAFGNASVELYLPGLPSMAAALHASPAEAQWTLSSFLVGFGIGQLFWGPVG 77 ++L L +L F + + LP +A + PA W ++F++ F IG +G + Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 78 DSFGRRIPLLVAISVYIVASLGCILSSSIHEV-IAWRLLQAFGACAGPVLARAVVRDVYG 136 D G + LL I + S+ + S + I R +Q GA A P L VV Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 137 HHRSADILSLLLLAASFAPLLLPLAGGGLL-WFGWRAIFWGQVAFGAVAMVGMLLMDETL 195 L+ + + P GG + + W + + ++ + + + L Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL----LIPMITIITVPFLMKLL 189 Query: 196 PQARR 200 + R Sbjct: 190 KKEVR 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 226 bits (577), Expect = 8e-71 Identities = 114/185 (61%), Positives = 149/185 (80%), Gaps = 1/185 (0%) Query: 10 IAATLPTGIGYEWTGLSFQEKVAGSQALGLFALAILVVFLLLVALYESWSIPLSVMLIVP 69 +A+ LP GIGY+WTG+S+QE+++G+QA L A++ +VVFL L ALYESWSIP+SVML+VP Sbjct: 846 LASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVP 905 Query: 70 IGAIGAVLAVTVVGMPNDVYFKVGLITVIGLAAKNAILIVEFAKDL-RSEGHTAMEAAVT 128 +G +G +LA T+ NDVYF VGL+T IGL+AKNAILIVEFAKDL EG +EA + Sbjct: 906 LGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLM 965 Query: 129 AAKMRFRPILMTSLAFILGVVPLAIAAGAGAASQRALGTGVIGGMLAATTLGVIFVPVFY 188 A +MR RPILMTSLAFILGV+PLAI+ GAG+ +Q A+G GV+GGM++AT L + FVPVF+ Sbjct: 966 AVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFF 1025 Query: 189 VWVMK 193 V + + Sbjct: 1026 VVIRR 1030 Score = 59.1 bits (143), Expect = 2e-12 Identities = 31/156 (19%), Positives = 65/156 (41%), Gaps = 1/156 (0%) Query: 43 AILVVFLLLVALYESWSIPLSVMLIVPIGAIGAVLAVTVVGMPNDVYFKVGLITVIGLAA 102 AI++VFL++ ++ L + VP+ +G + G + G++ IGL Sbjct: 347 AIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLV 406 Query: 103 KNAILIVEFAKDLRSEGHTA-MEAAVTAAKMRFRPILMTSLAFILGVVPLAIAAGAGAAS 161 +AI++VE + + E EA + ++ ++ +P+A G+ A Sbjct: 407 DDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAI 466 Query: 162 QRALGTGVIGGMLAATTLGVIFVPVFYVWVMKQVAR 197 R ++ M + + +I P ++K V+ Sbjct: 467 YRQFSITIVSAMALSVLVALILTPALCATLLKPVSA 502
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.7 bits (66), Expect = 0.018 Identities = 37/160 (23%), Positives = 63/160 (39%), Gaps = 31/160 (19%) Query: 21 SVREALEAACREQIAVAEQKCAEAREEAQNSASMLESSIQQEQAATQNVDGAEQALDGSQ 80 +V +A+ + +E ++ A EAQ + + E+SI++ A D A + L +Q Sbjct: 109 AVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQ 168 Query: 81 SSLSSAESALSACLSQPHDDDGRCPDCSGEDSAVAEAEAAVEQAQSMLEQARAELDVATE 140 + L S + A D A+AEAAVEQA ATE Sbjct: 169 NKLQSLDPA---------------------DPGYAQAEAAVEQAG----------KEATE 197 Query: 141 DRISMEQRVDLAKQAQAMAEHTLEQTLQACNAHLATVDQA 180 + ++++ D +A A+ E+ T + A Sbjct: 198 AKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAA 237
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 45.1 bits (106), Expect = 9e-07 Identities = 59/331 (17%), Positives = 110/331 (33%), Gaps = 21/331 (6%) Query: 46 TAERQVIEQDKAKLAQREQAVTQAEQKCDAGFADERAALNDELREKRAQGERAIAEMREK 105 A + +E+ A + + +A A A +L + K Sbjct: 119 EARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKALEGAMNFSTADSAK 177 Query: 106 NLSALEVEISELKAKRLGAVAHAENAERERIRTEIAQERDAWTKQQ-GDARKQLNAERTE 164 LE E + L+A++ E A + K + L Sbjct: 178 I-KTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 236 Query: 165 FEKQKGALSALQSEVEGRQAELETSERTLERKEQ---------RLEQQNQRRSEQLDDEV 215 A SA +E +A LE + LE+ + + + + + Sbjct: 237 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAE 296 Query: 216 ERRVEDRRKSLEAALQSAKEENIRLREAFKTQDELLGAFEQLKLQLGGKDPAEILRALNS 275 + +E + + L A QS + + REA K + E+ ++ + R L++ Sbjct: 297 KADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN-KISEASRQSLRRDLDA 355 Query: 276 QADELKRLREELATRPTEEMRERYQALESEAKNQKTRADQLERQLSTNEAAVAEIGELRR 335 + K+L E ++ E+ + SEA Q R D L+ + + E Sbjct: 356 SREAKKQLEAEHQ-----KLEEQNKI--SEASRQSLRRD-LDASREAKKQVEKALEEANS 407 Query: 336 QGSELNAENKSLAQRASIFEGAANEAQAELK 366 + + L NK L + + E E QA+L+ Sbjct: 408 KLAALEKLNKELEESKKLTEKEKAELQAKLE 438 Score = 38.1 bits (88), Expect = 2e-04 Identities = 78/338 (23%), Positives = 142/338 (42%), Gaps = 35/338 (10%) Query: 14 LADLNARESWINTKESEIASRETAVATRERDATAERQVIEQDKAKLAQREQAVTQAEQKC 73 A L AR++ + + TA + + + AE+ + KA L + + Sbjct: 185 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG-AMNFSTA 243 Query: 74 DAGFADERAALNDELREKRAQGERAIAEMREK------NLSALEVEISELKAK--RLGAV 125 D+ A L ++A+ E+A+ + LE E + L+A+ L Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 126 AHAENAERERIRTEIAQERDAWTKQQGDARKQLNAERTEFEKQKGALSALQSEVEGRQAE 185 + NA R+ +R ++ R +A+KQL AE + E+Q A + + Sbjct: 304 SQVLNANRQSLRRDLDASR--------EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 355 Query: 186 LETSERTLERKEQRLEQQNQ---RRSEQLDDEVERRVEDRRKSLEAALQSAKEENIRLRE 242 +++ LE + Q+LE+QN+ + L +++ + +K +E AL+ A + L + Sbjct: 356 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS-REAKKQVEKALEEANSKLAALEK 414 Query: 243 AFKTQDELLGAFEQLKLQLGGKDPAEILR---ALNSQADELKRLREELATRP-------- 291 K +E E+ K +L K AE L QA+EL +LR A+ Sbjct: 415 LNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPG 474 Query: 292 TEEMRERYQALESEAKNQKTRAD--QLERQL-STNEAA 326 + + + QA ++ K + +A + +RQL ST E A Sbjct: 475 NKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETA 512
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 28.7 bits (64), Expect = 0.004 Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 5/28 (17%) Query: 19 RGWRAY--ARGERRAS---NWLVSKGVP 41 G AY ERRA ++L+SKG+P Sbjct: 264 IGSDAYNQGLSERRAQSVVDYLISKGIP 291
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.8 bits (59), Expect = 0.038 Identities = 11/25 (44%), Positives = 12/25 (48%) Query: 13 ALALAVALLGGCATSKEKLLTHGDS 37 ALAL LL GCA+S D Sbjct: 7 ALALGTTLLVGCASSGTDQQGRSDP 31
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 30.2 bits (68), Expect = 0.006 Identities = 17/113 (15%), Positives = 34/113 (30%), Gaps = 14/113 (12%) Query: 108 LKADYDYRR--STGELRQRVRGIYEI-----PGRSYGDNPTARVRVIS---DRDWVVTLD 157 + +D S + R Y+ P + V + V + Sbjct: 114 REEYFDAVMVMSARPEQDRWSRFYKTDNPQSPQNILANRTDVFVEIKRVSFLGGNVAQVY 173 Query: 158 ISADEYYGAEQV---KRALVRYPVK-VARVDVDPARNPFGLVIDCYEGTPQRI 206 + + G+ A ++Y V +VD +NP G ++ Y + Sbjct: 174 FTKESVTGSNSTKTDAVATIKYKVDGTPSKEVDRFKNPLGYQVESYRADVEVP 226
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 27.0 bits (59), Expect = 0.050 Identities = 14/30 (46%), Positives = 21/30 (70%), Gaps = 1/30 (3%) Query: 33 ELPPPAYQLAAQRAGIPSTVLYAVALQESG 62 +L PA QLA+Q++G+P ++ A A ESG Sbjct: 155 QLSLPA-QLASQQSGVPHHLILAQAALESG 183
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 30.9 bits (69), Expect = 0.004 Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 111 RAEVEQIKARPSALR--AAAPAQPRSPSRPTAKPEPPPLPFRIVGAELRAGQRSLSVT 166 RAEV + + SA++ A + + A P P + +E++ G RSL VT Sbjct: 89 RAEVLHVGTKTSAMQFILHHRADYVACTEMQAGPGSPDVT-----SEVKVGNRSLPVT 141
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 32.1 bits (73), Expect = 0.002 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARRLAADGYPVQQSHISRMAD---AVR---------YLLPA 201 +Q EL L DGY V Q+ +SR V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.028 Identities = 34/199 (17%), Positives = 74/199 (37%), Gaps = 14/199 (7%) Query: 8 IDLFTFNTVPMRAFHLSWMAFFVCFFAWFASAPLMPVIAREFALTPGQVADINI-AAVAA 66 +D +P L F + + P M + L+ ++ + I + Sbjct: 248 VDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYM--MKDVHQLSTAEIGSVIIFPGTMS 305 Query: 67 TILVRLIVGPLCDRYGPRRVYAGLMASGAIPVVALAFATDYAS---VLACRLGIGAIGAS 123 I+ I G L DR GP V + ++ + +F + S + +G + + Sbjct: 306 VIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFT 365 Query: 124 FVITQYHTSVMFAPNVVGAANAA-------SAGWGNAGAGGAQALVPMVLAALIALGLDE 176 + S GA + S G G A GG ++ P++ L+ + +D+ Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI-PLLDQRLLPMEVDQ 424 Query: 177 SSAWRAALVVPGAALLAMA 195 S+ + L++ + ++ ++ Sbjct: 425 STYLYSNLLLLFSGIIVIS 443
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 122 bits (306), Expect = 1e-35 Identities = 81/268 (30%), Positives = 122/268 (45%), Gaps = 15/268 (5%) Query: 6 MEHKQFSGRVALVLGAGSVGEGWGNGKAAAVAYAREGATVIAVDLNLDAARETHGIIHQE 65 M K G++A + GA G G+A A A +GA + AVD N + + + E Sbjct: 1 MNAKGIEGKIAFITGAAQ-----GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE 55 Query: 66 GGRSEALAADVTQADQVAALVQGVVERHGRIDILHNNVGMARMGSVTELSEAQWDTAMNV 125 +EA ADV + + + + G IDIL N G+ R G + LS+ +W+ +V Sbjct: 56 ARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSV 115 Query: 126 NLKSAFLACKHVLPVMQAQKRGSIVNISSLAAIRYTGYP---YPVYYASKGGLNQLTVGL 182 N F A + V M ++ GSIV + S A G P Y +SK T L Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPA----GVPRTSMAAYASSKAAAVMFTKCL 171 Query: 183 ALEYAKQGIRVNAIMPGYVDTPLIYKDISGQYGSREEM---VNERNARCPMGHMGTAWDI 239 LE A+ IR N + PG +T + + + + G+ + + + P+ + DI Sbjct: 172 GLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDI 231 Query: 240 ANAAVFLASDAAAYITGVCLPVDGGVHL 267 A+A +FL S A +IT L VDGG L Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDGGATL 259
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.9 bits (62), Expect = 0.007 Identities = 12/31 (38%), Positives = 14/31 (45%) Query: 1 MIARLMVLACVTAALAGCAGAPASPPPPTDP 31 M RL LA T L GCA + +DP Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDP 31
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 30.2 bits (68), Expect = 0.001 Identities = 6/46 (13%), Positives = 22/46 (47%), Gaps = 3/46 (6%) Query: 40 AIDQVDDRVTKTQQR---LDRVEQTLENRPGYADLHAVRAEMAQTN 82 + + ++++ + ++ L V + N Y ++ ++ E+ +T Sbjct: 396 SEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKKELIETG 441
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 29.5 bits (65), Expect = 0.037 Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 12/90 (13%) Query: 401 APFGFAERDDGSVRLRADTMADRLDREAEPAMAALMEPVRRLVANAGSLQEIRDGLFSLY 460 +P+ FA+ DG L A ++ D PA+ L PVR V AG L G+ S+ Sbjct: 20 SPYAFADDYDGIPNLTAVQISPNAD----PAL-GLEYPVRPPVPGAGGLNASAKGIHSIA 74 Query: 461 EGMPSEQLAVVMRRAMAAAALAGRADVVEG 490 G +E A AA G + G Sbjct: 75 IGATAEA-------AKGAAVAVGAGSIATG 97
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 770 bits (1989), Expect = 0.0 Identities = 282/873 (32%), Positives = 420/873 (48%), Gaps = 40/873 (4%) Query: 11 LRYACGLVSALFACGIGASVAAEASSAQVAEVQFNTDMLRGFGDAPVDISRFNRGNFAAP 70 L ++ F A A + AE+ FN L A D+SRF G P Sbjct: 16 LHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPP 75 Query: 71 GDYTVPIVVNDRRVGRGTVRLRQLAGEAYPQPCVDTDLLTTAGVNVQRLDDAAQAQLQEN 130 G Y V I +N+ + V E PC+ L + G+N + ++ Sbjct: 76 GTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA--DD 133 Query: 131 SCVRLPGLIPDARAEFDNGEQHLYLSIPQIWLNRSARGYVDPDHWNEGITAGMLRYNANV 190 +CV L +I DA A+ D G+Q L L+IPQ +++ ARGY+ P+ W+ GI AG+L YN + Sbjct: 134 ACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSG 193 Query: 191 YRYNSRHGSASTQGYLGLDSGFNVGAWRFRHRGNLSYQENLG-----THYESIQTSVQRS 245 +R G S YL L SG N+GAWR R SY + ++ I T ++R Sbjct: 194 NSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERD 253 Query: 246 LAPIKSQLTAGEFFTEGDVLESLNLRGVRLSSDDRMYPESLRGYAPTVHGIANSNARVSI 305 + P++S+LT G+ +T+GD+ + +N RG +L+SDD M P+S RG+AP +HGIA A+V+I Sbjct: 254 IIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTI 313 Query: 306 RQNGIVIYETTVAPGEFQIDDLYPTGYGGDLEVVVTEADGSVHISRVPFSAPINALRAGA 365 +QNG IY +TV PG F I+D+Y G GDL+V + EADGS I VP+S+ R G Sbjct: 314 KQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGH 373 Query: 366 TRYSLAAGQYRNTMG-GETPYVFQGTVRHGFNNLVTGYGGITASEHYLAGEVGAALNT-S 423 TRYS+ AG+YR+ E P FQ T+ HG T YGG ++ Y A G N + Sbjct: 374 TRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGA 433 Query: 424 WGAFSLDATYARARLRNQPDRRGQSYGLSYSRLYEPTATSVTLAAYRYSTDGFLNLADTV 483 GA S+D T A + L + GQS Y++ + T++ L YRYST G+ N ADT Sbjct: 434 LGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTT 493 Query: 484 ALRSAD--------------SLYALPRGYGSAKGRLQVMLNQPLGERWGSLYLSGYSQNY 529 R + +G+LQ+ + Q LG R +LYLSG Q Y Sbjct: 494 YSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLG-RTSTLYLSGSHQTY 552 Query: 530 WGHSGRDTEYQAGYSNSFKRVNYNISASRQYSAYSGKWENTYMLNFSLPLGSGANAPR-- 587 WG S D ++QAG + +F+ +N+ +S S +A+ + LN ++P + Sbjct: 553 WGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKS 612 Query: 588 ------SNTTIQRNNRTRSTFIYETVNGSLGGSDSPLYYGVSASHSRHGGQGANSNNVSA 641 ++ ++ + R T V G+L D+ L Y V ++ GG G + + A Sbjct: 613 QWRHASASYSMSHDLNGRMT-NLAGVYGTL-LEDNNLSYSVQTGYAG-GGDGNSGSTGYA 669 Query: 642 NASWTSPLAQLGASASRSSNSSQASASISGAAVAWGGGVALTPSLGDTFAIVDAQGAAGA 701 ++ S S + Q +SG +A GV L L DT +V A GA A Sbjct: 670 TLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDA 729 Query: 702 RIANMGGLRVNSRGYGVVSNLTPFAQNTIEVDPNGLPLNVQFKSTIQHVAPTAGAIVPVK 761 ++ N G+R + RGY V+ T + +N + +D N L NV + + +V PT GAIV + Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 762 FEVEAGGQAAVIRARQADGQALPFGAQALDGNGNQVGTVAQGSRIIASSLKDTKGRITIK 821 F+ G ++ + + LPFGA + G VA ++ S + G++ +K Sbjct: 790 FKARVG--IKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPL-AGKVQVK 846 Query: 822 WGATAAQQCTVDYALPEAAGKADQPFHLLQGTC 854 WG C +Y LP Q L C Sbjct: 847 WGEEENAHCVANYQLPPE--SQQQLLTQLSAEC 877
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 4/37 (10%) Query: 19 SGVSLAVEPG----QVLGLLGANGAGKSTLLAALAGE 51 V+ +EPG + L G G GKSTL+ L G Sbjct: 583 GHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.3 bits (65), Expect = 0.006 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 8/75 (10%) Query: 34 VQIEQVTKERAKWRDS-IRVFAEATATAWEEHQVAPNPAKTAALRARLATSINP--KDDE 90 + +E TK K+ D R+F T+W HQ P+ T ++R + I P DD+ Sbjct: 100 IDVESSTKSFQKFGDQRYRIF-----TSWVSHQNDPSKINTRSIRNFMENIIQPPILDDK 154 Query: 91 QDAKILSHFDDLFSG 105 + A+ L F+G Sbjct: 155 EKAEFLKSAKQSFAG 169
>PF04183#IucA / IucC family Length = 580 Score = 29.1 bits (65), Expect = 0.032 Identities = 40/176 (22%), Positives = 58/176 (32%), Gaps = 24/176 (13%) Query: 123 GMAVPDWISSLPAVGPRLAVYWQTYLGEPHALGALVELVSG---------EHLGNIYRMV 173 G W+ + A L LGEP A E + E LG I+R Sbjct: 295 GPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRE- 353 Query: 174 LSATGNAFQLLLN--VVFMLITLFFVYKDGDRMIAQLDVLGERILPTRWQR--FSRVVPA 229 N + L ++ TL ++ + + W F VV Sbjct: 354 -----NPCRWLKPDESPVLMATLMECDENNQPLAGAYIDR-SGLDAETWLTQLFRVVVVP 407 Query: 230 TVGS-TVTGMSLIAVGEGVVLGVAYWLAGVPSPVLLGVVTGFMALIPGGAPLSFTL 284 G++LIA G+ + L + GVP VLL G M L+ P +L Sbjct: 408 LYHLLCRYGVALIAHGQNITLAMK---EGVPQRVLLKDFQGDMRLVKEEFPEMDSL 460
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.8 bits (124), Expect = 2e-09 Identities = 18/98 (18%), Positives = 36/98 (36%), Gaps = 5/98 (5%) Query: 110 AEVDRAAAQLAAARARVAFTASELARGK-RLLAENAIARRDFESKRNDAREAAANLQAAE 168 + A +L ++++ SE+ K + + + K + N+ Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTD---NIGLLT 315 Query: 169 AALDAAKLNLGYTEIVAPVDGRVSRAEI-TEGNVVAAG 205 L + + I APV +V + ++ TEG VV Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Score = 50.2 bits (120), Expect = 8e-09 Identities = 26/148 (17%), Positives = 47/148 (31%), Gaps = 31/148 (20%) Query: 49 VAPALGKTIVDWQDYSGRLEAIDRVDIRPLVSGTLTAVHFQDGSLVHKGDPLFTIDPRPY 108 VA A GK SGR +I+P+ + + + ++G V KGD L + Sbjct: 83 VATANGKLTH-----SGR-----SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGA 132 Query: 109 AAEVDRAAAQLAAARARVA---------------------FTASELARGKRLLAENAIAR 147 A+ + + L AR + + +L ++ + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 148 RDFESKRNDAREAAANLQAAEAALDAAK 175 F + +N + NL A Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVL 220
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1098 bits (2841), Expect = 0.0 Identities = 436/1042 (41%), Positives = 663/1042 (63%), Gaps = 16/1042 (1%) Query: 3 ISKFFIDRPIFAGVLSVIVLLAGLLAMFQLPISEYPEVVPPSVVVRAQYPGANPKVIAAT 62 ++ FFI RPIFA VL++I+++AG LA+ QLP+++YP + PP+V V A YPGA+ + + T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VASPLEESINGVEDMLYMQSQANSDGNLAVTVYFKLGVDPDKAQQLVQNRVSQALPRLPP 122 V +E+++NG+++++YM S ++S G++ +T+ F+ G DPD AQ VQN++ A P LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 123 DVQRLGVTTTKSSPTLTLVVHLISPNDRYDITYLRNYAVLNVKDRLSRIGGVGEVQIWGS 182 +VQ+ G++ KSS + +V +S N + +Y NVKD LSR+ GVG+VQ++G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 183 GSYSMRVWLDPQKVAQRGLTATDVVNAIREQNVQVAAGVIGASPTQGDVPMQFSVNAQGR 242 Y+MR+WLD + + LT DV+N ++ QN Q+AAG +G +P + S+ AQ R Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 243 LQNETEFGNIILKSSPDGAVTRLSDVARIELGAQEYGLRSLLNNKPAIGMGIMQSPGANA 302 +N EFG + L+ + DG+V RL DVAR+ELG + Y + + +N KPA G+GI + GANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 LDVSAQVRETMKELSADFPPGLEYRIEYDPTQFVRSSIKAVISTLLEAIALVVLVVIVFL 362 LD + ++ + EL FP G++ YD T FV+ SI V+ TL EAI LV LV+ +FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 QTWRASIIPLLAVPVSIVGTFSLLLLFGYSINALSLFGMVLAIGIVVDDAIVVVENVERN 422 Q RA++IP +AVPV ++GTF++L FGYSIN L++FGMVLAIG++VDDAIVVVENVER Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 IA-AGLTPREATYRAMREVSGPIIAIALTLCAVFVPLAFMTGLSGQFYKQFAMTIAISTV 481 + L P+EAT ++M ++ G ++ IA+ L AVF+P+AF G +G Y+QF++TI + Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAFNSLTLSPALSALLLKGHHDKPDWLTRGMNRVFGGFFNWFNRFFGRASDSYATGITG 541 +S +L L+PAL A LLK ++ + GGFF WFN F + + Y + Sbjct: 480 LSVLVALILTPALCATLLKP-------VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 542 VIRRKGGAMAVYAVLLAATVGISYLVPGGFVPAQDKQYLIGFAQLPNGASLDRTEDVIRR 601 ++ G + +YA+++A V + +P F+P +D+ + QLP GA+ +RT+ V+ + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 602 MSDIALK--EPGVESAIAFPGLSINGFTNSSSAGIVFVTLKPFDERHSAELSGNAITGSL 659 ++D LK + VES G S +G + +AG+ FV+LKP++ER+ E S A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRA 650 Query: 660 NAKFASIKDAFIAVFPPPPVMGLGTMGGFKLQIEDRAALGYAELDKATQAFLAKARQAP- 718 + I+D F+ F P ++ LGT GF ++ D+A LG+ L +A L A Q P Sbjct: 651 KMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPA 710 Query: 719 ELGPTFSNYQINVPQLDVDLDRVKAKQLGVPVTDVFDTLQIYLGSMYVNDFNRFGRVFQV 778 L N + Q +++D+ KA+ LGV ++D+ T+ LG YVNDF GRV ++ Sbjct: 711 SLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKL 770 Query: 779 RAQADAPFRAHPDDILQLKTRSDSGQMVPLSALVDVKQTFGPEMVVRYNGYTAADINGGP 838 QADA FR P+D+ +L RS +G+MVP SA +G + RYNG + +I G Sbjct: 771 YVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA 830 Query: 839 APGYSSDQAQDAAERIAAETLPRGVKFEWTDLTYQQILAGNAGIWVFPISVLLVFLVLAA 898 APG SS A E +A++ LP G+ ++WT ++YQ+ L+GN + IS ++VFL LAA Sbjct: 831 APGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 899 LYESLTLPLAVILIVPMSILAALTGVWLTSGDNNIFTQIGLMVLVGLSAKNAILIVEFAR 958 LYES ++P++V+L+VP+ I+ L L + N+++ +GL+ +GLSAKNAILIVEFA+ Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 959 EL-EMQGSTPLQAAIEASRLRLRPILMTSIAFIMGVVPLVLSSGAGSEMRHAMGVAVFFG 1017 +L E +G ++A + A R+RLRPILMTS+AFI+GV+PL +S+GAGS ++A+G+ V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1018 MLGVTLFGLFLTPVFYVLLRTL 1039 M+ TL +F PVF+V++R Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRC 1031 Score = 89.9 bits (223), Expect = 3e-20 Identities = 64/325 (19%), Positives = 127/325 (39%), Gaps = 14/325 (4%) Query: 733 QLDVDLDRVKAKQLGVPVTDVFDTL-----QIYLGSMYVNDFNRFGRVFQVRAQADAPFR 787 + + LD + + DV + L QI G G+ A F+ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ-LGGTPALPGQQLNASIIAQTRFK 241 Query: 788 AHPDDILQLKTRSD-SGQMVPLSALVDVKQTFGP-EMVVRYNGYTAADINGGPAPGYSS- 844 P++ ++ R + G +V L + V+ ++ R NG AA + A G ++ Sbjct: 242 N-PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 845 DQAQDAAERIA--AETLPRGVKFEWT-DLTYQQILAGNAGIWVFPISVLLVFLVLAALYE 901 D A+ ++A P+G+K + D T L+ + + +++LVFLV+ + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 902 SLTLPLAVILIVPMSILAALTGVWLTSGDNNIFTQIGLMVLVGLSAKNAILIVE-FAREL 960 ++ L + VP+ +L + N T G+++ +GL +AI++VE R + Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 961 EMQGSTPLQAAIEASRLRLRPILMTSIAFIMGVVPLVLSSGAGSEMRHAMGVAVFFGMLG 1020 P +A ++ ++ ++ +P+ G+ + + + M Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 1021 VTLFGLFLTPVFYVLLRTLSARKLH 1045 L L LTP L + + H Sbjct: 481 SVLVALILTPALCATLLKPVSAEHH 505
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 9e-04 Identities = 23/192 (11%), Positives = 56/192 (29%), Gaps = 36/192 (18%) Query: 74 TLNALETQAQQANHSLQAAAARLKQAR--ALLGNARSEQFPTVDAGFGPTRQRPSPASQG 131 L AL +A ARL+Q R L + + P + P Q Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL-------PDEPYFQN 178 Query: 132 LSANDSTDPSTLWRAQVGVSYEVDLFGRVASTVDAATADVQQSEALYRSVLLALQADVAQ 191 +S + V T+ +++ + +++ + ++ + Sbjct: 179 VSEEE---------------------------VLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Query: 192 AYFQVRELDAGLQLYRQTVELRAETLQLIQRRYDAGDISELDLARARSELESARSEALGF 251 + + A + Y + L I++ + ++ A +E + Sbjct: 212 KRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVY 271 Query: 252 ERRRANAEHALA 263 + + E + Sbjct: 272 KSQLEQIESEIL 283
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 49.5 bits (118), Expect = 1e-08 Identities = 56/331 (16%), Positives = 111/331 (33%), Gaps = 50/331 (15%) Query: 26 LPEVGADLGVSLSSAGLLVTGYALGVVVGAPPVAILTTRMPRKTLLLALMVIFTLGNLAC 85 LP++ D +S + T + L +G L+ ++ K LLL ++I G++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 86 ALAPGYGT-LMAARVLTSLAHGAFFGVGSVVATSLVKPEKQASAIALMFTGLTLANVLGV 144 + + + L+ AR + AF + VV + E + A L+ + + + +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 145 PFGTWLGQAWGWRATFWAVTVVGIVAMLAIATWVPRSRGDRGGDLMG------------- 191 G + W + I + R D+ G Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFML 216 Query: 192 ----------------------ELRALSRPQV----------LLGFAMTVLGFGGVFTAF 219 +R ++ P V ++G + FG V Sbjct: 217 FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV 276 Query: 220 TYIAPLLTELAGFSPGAVSPILLLFGVGLVAGNTY-GGKLADR---RLMPTLVGSLALLA 275 + + ++ ++ S + +++ G V Y GG L DR + + + ++ Sbjct: 277 SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS 336 Query: 276 IVLAVFSLTVHAQFAAVATVAVLGAAAFATV 306 + A F L + F + V VLG +F Sbjct: 337 FLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (295), Expect = 2e-33 Identities = 82/263 (31%), Positives = 127/263 (48%), Gaps = 11/263 (4%) Query: 67 LNGKVTVVTGGSKGIGLAVANAFAAEGAYVAIIARNPEGLEQARAQLQASGHNVAAYAAD 126 + GK+ +TG ++GIG AVA A++GA++A + NPE LE+ + L+A + A+ AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 127 LSDPQAAAQAIERIETEIGPIDILVNSAGAARRHQPEDLDPAKWRAAMDAKFFPYIHVQD 186 + D A + RIE E+GPIDILVN AG R L +W A + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 187 AVLPRMRARAANRPAGATNGIVVNIIGNGGKRPTSIHLAGGSANAALMLSTVGLAAHYAQ 246 +V M R +G +V + N P + A S+ AA ++ T L A+ Sbjct: 126 SVSKYMMDR--------RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE 177 Query: 247 YGIRINAINPGPIFTQRVEQA-LDLDASQRGITRDAALAENQAHIPLGRYGKAEEVADVA 305 Y IR N ++PG T D + +++ I + IPL + K ++AD Sbjct: 178 YNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSL--ETFKTGIPLKKLAKPSDIADAV 235 Query: 306 LFLASARASYVVGAIIPMDGGAS 328 LFL S +A ++ + +DGGA+ Sbjct: 236 LFLVSGQAGHITMHNLCVDGGAT 258
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 27.2 bits (60), Expect = 0.024 Identities = 11/26 (42%), Positives = 19/26 (73%) Query: 65 GLEGLTPSVLAEQLAVARNTLSFHLK 90 G++GLT LA++L + + TL +H+K Sbjct: 21 GIDGLTTRKLAQKLGIEQPTLYWHVK 46
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 1e-08 Identities = 34/147 (23%), Positives = 49/147 (33%), Gaps = 16/147 (10%) Query: 200 DDLIERVERTRKAQPTLTIRAPSTGLLQTLNVR-NGMAVSAGTVLAQLNGLDAV-WLDAA 257 L + + + Q IRAP + +Q L V G V+ L + D + A Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTAL 371 Query: 258 VPETQARAMRPGLEAKVSFPAFPG---HTVVGKVSYILPEVDAASRT-----ARIRIELQ 309 V + G A + AFP +VGKV I + R I IE Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEEN 431 Query: 310 -----NPDGQLRPGLFAKVEFAHTGEK 331 N + L G+ TG + Sbjct: 432 CLSTGNKNIPLSSGMAVTA-EIKTGMR 457 Score = 33.6 bits (77), Expect = 0.002 Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 3/56 (5%) Query: 217 TIRAPSTGLLQTLNVRNGMAVSAGTVLAQLNGLDAVWLDAAVPETQARAMRPGLEA 272 I+ +++ + V+ G +V G VL +L L A +A +TQ+ ++ LE Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGA---EADTLKTQSSLLQARLEQ 150
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 685 bits (1769), Expect = 0.0 Identities = 222/1058 (20%), Positives = 437/1058 (41%), Gaps = 50/1058 (4%) Query: 5 LIRWSINNRFLVLLATLFLFFWGLWAIKNAPIDALPDLSDVQVIVRTTYPGQAPQIVENQ 64 + + I + + L G AI P+ P ++ V V YPG Q V++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTYPLATTMLSVPGAKTVRGYSF-FGDSFVYIIFEDGTDLYWARSRVLEYLNQVQGRLPA 123 VT + M + + S G + + F+ GTD A+ +V L LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 TAK-PSLGPDATGVGWIYEYALVDRSGNHDLSQLRGLQDWFLKYELKSVPDVAEVASIGG 182 + + + + ++ V + + +K L + V +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 183 MVKQYQIVIDPIKLAAFGVTQDQVIQAVRASNQEVGG------SVLELAEAEYMVRASGY 236 +I +D L + +T VI ++ N ++ L + + A Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 237 LASLEDFRNIPLAVKSGGTPILLGDVATIQLGPEIRRGIAELNGEGETAGGVVILRSGKN 296 + E+F + L V S G+ + L DVA ++LG E IA +NG+ AG + L +G N Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGAN 298 Query: 297 ARQAISAVKAKLDELKASLPPGVEIVPTYDRSKLIDRAIENLTSKLIEEFIVVALVCAIF 356 A A+KAKL EL+ P G++++ YD + + +I + L E ++V LV +F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 357 LWHLRSALVAIISLPLGVLTAFIIMHYQGVSANIMSLGGIAIAIGAMVDAAVVMIENAHK 416 L ++R+ L+ I++P+ +L F I+ G S N +++ G+ +AIG +VD A+V++EN + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 417 HVETWRHEHLGQELRGEAHWRVMANAAAEVGPALFFSLLIITLSFIPVFTLQAQEGRLFG 476 + + +++ AL ++++ FIP+ G ++ Sbjct: 419 VMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 477 PLAFTKTYAMAGAAGLAVTLVPVLMGYWIRGRIPP--EEKNPLNRFLIRIYRPLLD---- 530 + T AMA + +A+ L P L ++ E K + + ++ Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTN 528 Query: 531 ---AVLRRPRTTLAAALIILLTAIWPATRLGGEFLPPLDEGDLLYMPSALPGLSASKASE 587 +L L +I+ + RL FLP D+G L M G + + + Sbjct: 529 SVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQK 588 Query: 588 LL-QLTDR-MIRTVPEVASVFGKAGRAETATDPAPLEMFETTVQLKPHDQW-RPGMTVDK 644 +L Q+TD + V SVF G + + F V LKP ++ + + Sbjct: 589 VLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAF---VSLKPWEERNGDENSAEA 645 Query: 645 LIQALDDAVKVPGLANIWVPPIRNRLDML-ATGIKSPIGVKVAAANLADIESVALAIEQV 703 +I + + + +++ ATG + + + A ++ + Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 704 AKTVPGVSSALAERLTGGRYVDVQVDRISAARYGLSIADVQSVVSAAVGGENIGETVEGL 763 A+ + S L ++VD+ A G+S++D+ +S A+GG + + ++ Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 764 ARYPINVRYPREIRDSVEGLRNLPMFTSNGQQITLGTVARIAIENGPPMLKSENARPTGW 823 + V+ + R E + L + ++NG+ + G P L+ N P+ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS-- 823 Query: 824 VYIDVRGRDLASVVSDLRHAVAQQVA--LKPGMSISFSGQFEYMERATARLTLVIPATLL 881 ++++G S A+ + +A L G+ ++G + + ++ + + Sbjct: 824 --MEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFV 881 Query: 882 IIFVLLYLTFRRFDEALLIMATLPFALVGGVWFLYLLNYHLSVPAGIGFIALAGVSAEFG 941 ++F+ L + + + +M +P +VG + L N V +G + G+SA+ Sbjct: 882 VVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNA 941 Query: 942 VVMLFYLKQAAASRQDSGLSLTPSVLEDAIREGAVMRVRPKAMTVAVILAGLLPILLGSG 1001 ++++ + K + G + +A MR+RP MT + G+LP+ + +G Sbjct: 942 ILIVEFAKDL---MEKEGKG-----VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNG 993 Query: 1002 AGSEIMSRIAAPMVGGMITAPLLSMFVIPAAYRLMRGR 1039 AGS + + ++GGM++A LL++F +P + ++R Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.0 bits (67), Expect = 0.004 Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 11/81 (13%) Query: 29 LQTSLDSPAGGITT-YTEFADSANHVKASLTKTGQDG---VITLHIGDGWHVNAN----- 79 + S G ++ ++ S + SL+ G+ + L+ D +NAN Sbjct: 338 VHASFFDIGGSVSAGFSNSNSSTVAIDHSLSLAGERTWAETMGLNTADTARLNANIRYVN 397 Query: 80 --PASLDNLIPTSVLVVGDGE 98 A + N++PT+ LV+G + Sbjct: 398 TGTAPIYNVLPTTSLVLGKNQ 418
>cloacin#Cloacin signature. Length = 551 Score = 32.0 bits (72), Expect = 0.008 Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 7/114 (6%) Query: 375 AHDMSGMDMGGESGGSMKG--MDHGSMSNADQSSSGAGNQGAMSGMDHGSMGGMAGMSHG 432 AH SG GG +G + G D S+ + G G G G G + G Sbjct: 13 AHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72 Query: 433 GMNHGAGDGEGGMVEVKHPYPAENSP-----ATTMPPDVVSTRLDDPGVGLRGN 481 G + G+ V +PA ++P A ++ +S + D L+G Sbjct: 73 GGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 8e-19 Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 1/126 (0%) Query: 2 RILVIEDERKLAHYLQKGLTEHNYVVDIASNGVDGRHAALEGNYDLVVLDVMLPGIDGFW 61 ILV +D+ + L + L+ Y V I SN G+ DLVV DV++P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILKDLRET-KDTPVLMLTARDKVEDRVRGLENGADDYLVKPFAFSELLARIQALLRRGRG 120 +L +++ D PVL+++A++ ++ E GA DYL KPF +EL+ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 QESTLL 126 + S L Sbjct: 125 RPSKLE 130
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 27.9 bits (62), Expect = 0.008 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 4/46 (8%) Query: 1 MKRISCAIVAAAISFGAIGIVHAETKT----RAQVRAELQEAKAKG 42 MK+I+C AA+ G A T T AQ A+ Q K G Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGG 46
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.3 bits (63), Expect = 0.045 Identities = 16/130 (12%), Positives = 40/130 (30%), Gaps = 20/130 (15%) Query: 178 VRHYRKRWIEPRRSGRLVVGSNAGTADYKRWLDMVEGA-ALLPKHLRDQI--IILIAGVP 234 + Y+ + +++G Y +++ +P R + +L++ Sbjct: 107 IDKYQAEF---GTQKVILIG-------YSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQ 156 Query: 235 PSEDQVSKVEQLGMMDHVIFVGLLDDVRPFIATLDVGFVL---SSEVETISFACREMMAM 291 S+ ++ E + + P + +L E + C E+ Sbjct: 157 SSDFEIHVSEMVTSDNQ----SARYLTLPEVNKQTTVPMLCLYGKEDDAPLHLCPEVKQP 212 Query: 292 GVPVIVSDSG 301 V V+ G Sbjct: 213 NVTVMELSGG 222
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 649 bits (1677), Expect = 0.0 Identities = 224/1077 (20%), Positives = 413/1077 (38%), Gaps = 78/1077 (7%) Query: 8 LSVRARWAVLFLFLAIGALGVWQLTKLPIDAVPDITNNQVQINTVDPRLSPVEIEKLVTY 67 +R L + + G + +LP+ P I V ++ P ++ VT Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 68 PVEISLAGIPGLESTRSIS-RNGFSQVTAIFTDKTDLYFARQQVGERLIKAQESLPDGVQ 126 +E ++ GI L S S G +T F TD A+ QV +L A LP VQ Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 127 PQIGPVTTGLGEVLLYTVGYTYPDGEGAQKVAGEPGWQPDGSYLTPEGDRMVDEVAKAGY 186 Q V L+ G+ + Q Sbjct: 124 QQGISVEKSSSSYLMV-AGFVSDNPGTTQ-----------------------------DD 153 Query: 187 LRTVQDWIVAPQLKALPGVAGVDSIGGYAKTFVVEPNPTKLASYGISYSELGEALERANI 246 + V L L GV V G + + L Y ++ ++ L+ N Sbjct: 154 ISDYVASNVKDTLSRLNGVGDVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQND 212 Query: 247 AVGANYYNRGGEA------YLVRVDARVGSVDEIRN-AVAATRGGVPITVGQIADVKIGG 299 + A + R + +E + G + + +A V++GG Sbjct: 213 QIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGG 272 Query: 300 DLRTGAGSMNGEEAVIGTVLMLIGENSRVVAEDVSAKLDQIATSLPPGIQVKTVLDRAKL 359 + +NG+ A + + G N+ A+ + AKL ++ P G++V D Sbjct: 273 ENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPF 332 Query: 360 VNATVSTVERNLTEGAILVAASLFLLLGNWRAALIAVLVIPFSFLMMAMGMNAFKVPGNL 419 V ++ V + L E +LV ++L L N RA LI + +P L + AF N Sbjct: 333 VQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT 392 Query: 420 MSLG--ALDFGLIVDGSVIIIENCLARLAHRQQHEGRLLFLRERLEETMRAAQEMIKPTV 477 +++ L GL+VD +++++EN R E +L E T ++ ++ V Sbjct: 393 LTMFGMVLAIGLLVDDAIVVVENV-----ERVMMEDKL----PPKEATEKSMSQIQGALV 443 Query: 478 FGQVIILLTFAPLLMFTGVEGKTFSPMAITIMLALVAAFILAITLVPALVAILIRGRVAE 537 +++ F P+ F G G + +ITI+ A+ + ++A+ L PAL A L++ AE Sbjct: 444 GIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503 Query: 538 KE-------VWLI---AKSKERYLPFLDKAIARPWPFIFAGLVFFLAAIPAFGLLGSEFI 587 W S Y + K + ++ + + F L S F+ Sbjct: 504 HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFL 563 Query: 588 PKLDEKNLAVASTRVPSVSLEQSLAMQLKVEDAIKKLPEVELMFSKTGTAEVATDPMPPN 647 P+ D+ + E++ + +V D K + + S + N Sbjct: 564 PEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANV-ESVFTVNGFSFSGQAQN 622 Query: 648 VSDGFVILKPQEEWPDGVTTKAQVIERV-EKAAGTQLGNLYEVSQPIELRFNELIAGVRG 706 FV LKP EE + VI R + + G + + P EL Sbjct: 623 AGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGTATGF 679 Query: 707 DVA-IKLYGDDLEKMQQTANEMVRVLQDIPGA-GSVKADQVGGAPTLDVKLNRAEIARYG 764 D I G + + Q N+++ + P + SV+ + + +++++ + G Sbjct: 680 DFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALG 739 Query: 765 LTVQDVADTIAAALGGRPSGLLYEGDRRFDITVRVPEATRMNLDAIRALPILLPEMEGQL 824 +++ D+ TI+ ALGG + R + V+ RM + + L + G++ Sbjct: 740 VSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYV--RSANGEM 797 Query: 825 RRQVPLARVAQIRLTEGLNEIRRENGKRRVVVQVNLDGRDAGSFVEEAQAKIAQV--QLP 882 VP + G + R NG + +Q G+ +A A + + +LP Sbjct: 798 ---VPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA---APGTSSGDAMALMENLASKLP 851 Query: 883 AGYYLEWGGQFESLQAASQRLSIVVPICFLAIFVLLFMALGGFGRALSVFLAVPLGLAGG 942 AG +W G + + + +V I F+ +F+ L + +SV L VPLG+ G Sbjct: 852 AGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGV 911 Query: 943 VFTLAMTGINFSVSAAVGFICLAGVAVLNGLVVMT-AIRAHTEAGLPLSEAIREGMKEKM 1001 + + V VG + G++ N ++++ A + G + EA ++ ++ Sbjct: 912 LLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRL 971 Query: 1002 RAVVMTGFVPAIGFVPMALALGTGAEVQKPLATTVIGGLIAATILTLLVLPAIAKVV 1058 R ++MT +G +P+A++ G G+ Q + V+GG+++AT+L + +P V+ Sbjct: 972 RPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 109 bits (274), Expect = 3e-26 Identities = 101/534 (18%), Positives = 202/534 (37%), Gaps = 46/534 (8%) Query: 557 AIARPWPFIFAGLVFFLAAIPAFGLLGSEFIPKLDEKNLAVASTRVPSVS---LEQSLAM 613 I RP ++ +A A L P + ++V S P ++ ++ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSV-SANYPGADAQTVQDTVTQ 63 Query: 614 QLKVEDAIKKLPEVELMFSKTGTAEVATDPMPPNVSDGFVILKPQEEWPDGVTTKAQVIE 673 +E + + + M S + +A T ++ F + D + QV Sbjct: 64 --VIEQNMNGIDNLMYMSSTSDSAGSVT------ITLTF------QSGTDPDIAQVQVQN 109 Query: 674 RVEKAAGTQLGNLYEVSQPIELRFNELIAGVRGDVAIKLYGDDLEKMQQT---ANEMVRV 730 +++ A L + Q + + + + + A+ + Sbjct: 110 KLQLA----TPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDT 165 Query: 731 LQDIPGAGSVKADQVGGAPTLDVKLNRAEIARYGLTVQDVADTIAAAL----GGRPSGLL 786 L + G G V G + + L+ + +Y LT DV + + G+ G Sbjct: 166 LSRLNGVGDV--QLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTP 223 Query: 787 YEGDRRFDITVRVPEATRMNLDAIRALPILLPEMEGQLRRQVPLARVAQIRL-TEGLNEI 845 ++ + ++ + N + + + V L VA++ L E N I Sbjct: 224 ALPGQQLNASIIA-QTRFKNPEEFGKVTLR----VNSDGSVVRLKDVARVELGGENYNVI 278 Query: 846 RRENGKRRVVVQVNL-DGRDAGSFVEEAQAKIAQVQ--LPAGYYLEWGGQFESLQAASQR 902 R NGK + + L G +A + +AK+A++Q P G ++ +++ Sbjct: 279 ARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQG--MKVLYPYDTTPFVQLS 336 Query: 903 LSIVVPICFLAI---FVLLFMALGGFGRALSVFLAVPLGLAGGVFTLAMTGINFSVSAAV 959 + VV F AI F+++++ L L +AVP+ L G LA G + + Sbjct: 337 IHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMF 396 Query: 960 GFICLAGVAVLNGLVVMTAI-RAHTEAGLPLSEAIREGMKEKMRAVVMTGFVPAIGFVPM 1018 G + G+ V + +VV+ + R E LP EA + M + A+V V + F+PM Sbjct: 397 GMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPM 456 Query: 1019 ALALGTGAEVQKPLATTVIGGLIAATILTLLVLPAIAKVVLEPKEKRKSDIPEG 1072 A G+ + + + T++ + + ++ L++ PA+ +L+P + G Sbjct: 457 AFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510 Score = 88.0 bits (218), Expect = 1e-19 Identities = 52/322 (16%), Positives = 116/322 (36%), Gaps = 24/322 (7%) Query: 218 FVVEPNPTKLASYGISYSELGEALERANIAVGANYYNRGGEAYLVRV---DARVGSVDEI 274 F +E + K + G+S S++ + + A N + G + V +++ Sbjct: 726 FKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDV 785 Query: 275 RNAVAATRGGVPITVGQIADVKIGGDLRTGAGSMNGEEAVIGTVLMLIGENSRVVAEDVS 334 + G + G+ + + + + D Sbjct: 786 DKLYVRSANGEMVPFSAFTTSHWV----YGSPRLERYNGLPSMEI-QGEAAPGTSSGDAM 840 Query: 335 AKLDQIATSLPPG--IQVKTVLDRAKLVNATVSTVERNLTEGAILVAASLFLLLGNWRAA 392 A ++ +A+ LP G + + +L + + ++V L L +W Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPAL---VAISFVVVFLCLAALYESWSIP 897 Query: 393 LIAVLVIPFSFLMMAMGMNAFKVPGNLMSLGAL--DFGLIVDGSVIIIENCLARLAHRQQ 450 + +LV+P + + + F ++ + L GL +++I+E + Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE----FAKDLME 953 Query: 451 HEGRLLFLRERLEETMRAAQEMIKPTVFGQVIILLTFAPLLMFTGVEGKTFSPMAITIML 510 EG+ + E T+ A + ++P + + +L PL + G + + I +M Sbjct: 954 KEGKGVV-----EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMG 1008 Query: 511 ALVAAFILAITLVPALVAILIR 532 +V+A +LAI VP ++ R Sbjct: 1009 GMVSATLLAIFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 48.7 bits (116), Expect = 2e-08 Identities = 33/200 (16%), Positives = 60/200 (30%), Gaps = 30/200 (15%) Query: 125 ASRDAAQLAAARTAAYARAELARKELAREQYLYKQQVSARVDLERAQAEAQAAAADARRA 184 A + + + A++E L+K ++ + Q A Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD----KLRQTTDNIGLLTLELA 319 Query: 185 KVEAEVANVTKDGQGVAVSSPISGRITTQSL-SLGAFVQPETELFRIA-DPKQIQVEAAI 242 K E + +P+S ++ + + G V L I + ++V A + Sbjct: 320 KNEERQQASV-------IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 243 LPSDIFRIAPGDRAIVELPG-----GGTLEAKVGSVTPSLNTATRQ------------AT 285 DI I G AI+++ G L KV ++ R Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENC 432 Query: 286 AVIDVEAGSLQPGLAVRVRI 305 + L G+AV I Sbjct: 433 LSTGNKNIPLSSGMAVTAEI 452 Score = 36.7 bits (85), Expect = 1e-04 Identities = 22/141 (15%), Positives = 48/141 (34%), Gaps = 17/141 (12%) Query: 76 LDAEIGAQAVVSPQPGGEAIVTARASGAVTQVFKRLGDPVQAGEVLA-VVASRDAAQLAA 134 ++ A ++ G + + V ++ + G+ V+ G+VL + A A Sbjct: 80 VEIVATANGKLTHS-GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 135 ARTA-AYARAELARKELAREQ-------------YLYKQQVSAR-VDLERAQAEAQAAAA 179 +++ AR E R ++ Y Q VS V + + Q + Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 180 DARRAKVEAEVANVTKDGQGV 200 ++ + E + + V Sbjct: 199 QNQKYQKELNLDKKRAERLTV 219
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 7e-22 Identities = 40/142 (28%), Positives = 74/142 (52%), Gaps = 4/142 (2%) Query: 1 MGKLKILVIEDERKLAEYLKRALSEHNYVVDIAMDGISGLHLAQETQYDLILLDVMLPGR 60 M ILV +D+ + L +ALS Y V I + + DL++ DV++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGFSVLAELRKGD-RVPILMLTARDKLEDRVRGLQDGADDYLAKPFALSELLA---RVLA 116 + F +L ++K +P+L+++A++ ++ + GA DYL KPF L+EL+ R LA Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 117 LSRRQSNSVIEPNRQNVLKVGD 138 +R+ + + + ++ + VG Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGR 142
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.8 bits (163), Expect = 2e-15 Identities = 27/98 (27%), Positives = 53/98 (54%), Gaps = 5/98 (5%) Query: 2 QYDLIILDINLPDMEGFEVLQRIRQSDA-VPVMMLTARTSLEDRVRGLEQGADDYLAKPF 60 DL++ D+ +PD F++L RI+++ +PV++++A+ + ++ E+GA DYL KPF Sbjct: 47 DGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106 Query: 61 ALSELQARVQALRRRGSGNESRRGPNVLRVADLELDLL 98 L+E + + R RR + + + L+ Sbjct: 107 DLTE----LIGIIGRALAEPKRRPSKLEDDSQDGMPLV 140
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 80.6 bits (199), Expect = 5e-19 Identities = 78/390 (20%), Positives = 134/390 (34%), Gaps = 64/390 (16%) Query: 1 MKKTILLAASAATFSAAAVHAETSVTLYGLIDTGIGYAKVDGSYTNPNTGAKADVNASRI 60 MKK+++ A T +A V A VTLYG I G+ T+ + AS Sbjct: 1 MKKSLI----ALTLAALPVAAMADVTLYGTIKAGV--------ETSRSVAHNGAQAASVE 48 Query: 61 GATTGQTAGSRWGLRGKEDLGDGLYATFRLESGFDSTNGESSQGGRLFGREATVGLGSAD 120 T GS+ G +G+EDLG+GL A +++E +S G R + +GL Sbjct: 49 TGTGIVDLGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGNRQ----SFIGL-KGG 103 Query: 121 WGEVRLGRQYNVASRMMGSLFGNQFGGFTQLTTGAGLGFSGSNWVRYDNL---ALYESPS 177 +G++R+GR +V + G + + Y+SP Sbjct: 104 FGKLRVGRLNSVL----------KDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPE 153 Query: 178 FGGFRLSAGYSFNANDLSAAQSGFATADNTRAITSGLSYNNGPLLAFIAYEQLNASNKLS 237 F G S Y+ N N + N + + Y A+ + Q+ + + Sbjct: 154 FAGLSGSVQYALNDNAGRHNSESYHAGFNYKNGGFFVQYGG----AYKRHHQVQENVNIE 209 Query: 238 NAQTSATPRSFTVGAAYDFEVLKLIAAYERATDGWFAGKGLPSGANINGFQGTPSNAFVD 297 Q + A Y +A ++ ++ + + + A+ Sbjct: 210 KYQIHRLVSGYDNDALYAS-----VAVQQQDAKLVEENY-----SHNSQTEVAATLAYRF 259 Query: 298 GFSTN--SYLLGVAVPLGGASSMFGSWQRVDPNNSDLTGGDSTSNTFALGYSYKLSKRTN 355 G T SY G ++ + +G Y SKRT+ Sbjct: 260 GNVTPRVSYAHGFKGSFDAT------------------NYNNDYDQVVVGAEYDFSKRTS 301 Query: 356 IYAAGSYTKNFAFQSDAKATEAIIGLRHVF 385 + + + +S +T +GLRH F Sbjct: 302 ALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 32.8 bits (74), Expect = 0.002 Identities = 53/205 (25%), Positives = 75/205 (36%), Gaps = 36/205 (17%) Query: 43 IVPMPQPLPLPGQLKAL-KDKPAPEQTSPTAQVNRANSEARMAPTR---DGFINAIQ--- 95 IV P P L Q KAL K+K A EQ + R + A R + NA+ Sbjct: 132 IVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQ 191 Query: 96 -----------VWPYSEGALYQVYASPGRVTLVQ---LQVGERLIDVSAGDTVRWIVGDS 141 + E L Q+ Q L+ E L A + VR D Sbjct: 192 NLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDK 251 Query: 142 SS-----GTGATARPNLQIKPIRAGLKTNLVVTTDRRIYLLELASTQSAWMAS----VSW 192 S + ++++ P + +TNLVV T++ +Y L Q AS V Sbjct: 252 ISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKL 311 Query: 193 DYPQDRLAA------LKRRNEAAAQ 211 +YPQ + LK+R EA Q Sbjct: 312 EYPQRHEVSSVIEEELKKREEAKRQ 336
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 26.3 bits (58), Expect = 0.014 Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 15 LKEGETGVPVADLCRKHGISNATYYQWKSK 44 +K G P+ D R H +SN++ Y+ + Sbjct: 129 IKNGSHSRPLTDFARSHFLSNSSAYRMREA 158
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 54.7 bits (131), Expect = 6e-10 Identities = 38/226 (16%), Positives = 82/226 (36%), Gaps = 22/226 (9%) Query: 153 SRARAQAVQALRHDIDRL--AQLQGQADARRADIQTMAAEAADQKTQLVAQQKERATLLA 210 +A +V + +I R+ A + A A ++ AE + Q+++ V + ++ AT Sbjct: 1003 IQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETT 1062 Query: 211 RLEGQIAAQRAEARQLGRDDNRLSHLIDDLEKAIAEQAEAARRAEEARRRAEAVKRAQEA 270 ++A + S++ + + E A+ E + + + A Sbjct: 1063 AQNREVAKEAK------------SNVKANTQ-----TNEVAQSGSETKETQTTETK-ETA 1104 Query: 271 RLAEEARRKAEAERRAEAARQARRNEEARDAARAREQVEAAAARERDQQREQQRGPVALA 330 + +E + K E E+ E + + Q +A ARE D + P + Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVT-SQVSPKQEQSETVQPQAEPARENDPT-VNIKEPQSQT 1162 Query: 331 DPDAAGLRPAGSGSGRIVPPQRPAAPTDRANQAADDDSADDESSRQ 376 + A +PA S + P + + N ++ ++ Q Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQ 1208 Score = 48.1 bits (114), Expect = 7e-08 Identities = 21/138 (15%), Positives = 46/138 (33%), Gaps = 6/138 (4%) Query: 243 AIAEQAEAARRAEEARRRAEAVKRAQEARLAEEARRKAEAERRA-EAARQARRNEEARDA 301 +AE ++ + E + AQ +A+EA+ +A + E A+ +E + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 302 ARAREQVEAAAARERDQQREQQRGPVALADPDAAGLRPAGSGSGRIVPPQRPAAPTDRAN 361 + + + + Q P + + P S + P PA D Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKV-----TSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 362 QAADDDSADDESSRQQAA 379 + S + ++ + Sbjct: 1154 NIKEPQSQTNTTADTEQP 1171
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 140 bits (354), Expect = 5e-45 Identities = 49/162 (30%), Positives = 86/162 (53%), Gaps = 6/162 (3%) Query: 1 MAEQDQN--TQQAGGDAPSFNLQRVYLKDLSLEMPNAPHVFLEQEQPQVEVSINVGGQRL 58 M+E++Q P +QR+Y+KD+S E PN PH+F + +P++ ++ +++ Sbjct: 1 MSEENQVNAADTQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQV 60 Query: 59 AETVFES--TVTATVTTRINDKVLYLVEGTQAGIFELANIPAEQMDALLGIVCPTMLYPY 116 + ++E ++ T + V ++ E QAG+F ++ + QM L CP ML+PY Sbjct: 61 GDDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPY 120 Query: 117 LRANVADAITRTSLPALHLAEVNFQALYEQRLAELAQQQGGN 158 R V+ + R + PAL+L+ VNF AL+ L Q+Q Sbjct: 121 ARELVSSLVNRGTFPALNLSPVNFDALFMDYLQR--QEQAEQ 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 104 bits (260), Expect = 6e-28 Identities = 44/119 (36%), Positives = 61/119 (51%), Gaps = 1/119 (0%) Query: 2 ARILVVDDEVGIRELLSEILYDEGHTVELAENAAEARAARLRTRPDLVLLDIWMPDTDGV 61 A ILV DD+ IR +L++ L G+ V + NAA DLV+ D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 SLLKEWGSQGLLDMPVIMMSGHATIDTAVEATRIGAMDFLEKPITLQRLLKTIAAGLAR 120 LL D+PV++MS T TA++A+ GA D+L KP L L+ I LA Sbjct: 64 DLLPRIKKAR-PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Score = 47.1 bits (112), Expect = 2e-08 Identities = 16/117 (13%), Positives = 30/117 (25%) Query: 115 AAGLARGRAPHPAPAIAPLAPATPPVPLEDELDPPAAALAAMPAAAEAAPLSNGRLGSIA 174 L L P P+E + + ++ Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 175 LDQPLREARDEFERIYFEYHLVRENHSMTRVSERTGLERTHLYRKLKQLGIESARKR 231 E E L + + ++ GL R L +K+++LG+ R Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSS 481
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.5 bits (92), Expect = 1e-06 Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 5/80 (6%) Query: 60 LAYDNGRAVGMVHWVLHRSCWTAGDYCYLQDLFVAPDVRGGGHGRALIEHVYAQARAVNA 119 L Y +G + RS W Y ++D+ VA D R G G AL+ A+ + Sbjct: 69 LYYLENNCIGRIKI---RSNWN--GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHF 123 Query: 120 ARVYWLTHETNHTAMQLYDR 139 + T + N +A Y + Sbjct: 124 CGLMLETQDINISACHFYAK 143
>INTIMIN#Intimin signature. Length = 939 Score = 28.9 bits (64), Expect = 0.034 Identities = 11/58 (18%), Positives = 25/58 (43%) Query: 155 QLDLPDAPPGLPRSVQVSAVAISNPHAVQQVDDVDAAPVAAIGPLIERHPRFARRVNA 212 L++P G RS Q + + + + + ++ D+A + G + + A+ A Sbjct: 455 SLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQA 512
>adhesinb#Adhesin B signature. Length = 310 Score = 248 bits (635), Expect = 5e-83 Identities = 83/334 (24%), Positives = 157/334 (47%), Gaps = 42/334 (12%) Query: 13 ILMMLALGTACASAPAMAR-AAEPLRVVATFSVLGDMVREIGGPDVAVTTLVGPDGDAHE 71 +L+ AC+S + + L VVAT S++ D+ + I G + + ++V D HE Sbjct: 10 LLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHE 69 Query: 72 YEPTPQAARQLAGAAVLIENGLSFET----WLPRLVKASGFAGRA--VVASQGIAPRKLA 125 YEP P+ ++ + A ++ NG++ ET W +LV+ + S+G+ L Sbjct: 70 YEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLE 129 Query: 126 DAEHEHDHGDDHDHDAGHEHGHGDADGHAHGHGTGHRHHHGDLDPHAWQSLTNGAVYARN 185 + DPHAW +L NG +YA+N Sbjct: 130 GQSEKGKE-----------------------------------DPHAWLNLENGIIYAQN 154 Query: 186 IGAGLAAADPEHAEAYRERAQAYIARIEALDARIRATFAAIPAARRQVVTSHDAFGYFGD 245 I L+ DP + E Y + +AY+ ++ ALD + F IP ++ +VTS F YF Sbjct: 155 IAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSK 214 Query: 246 AYGVRFIAVAGFSTDAEPSAADMARIVEQVKRERVPAVFVENITSPALVRQIARETGARV 305 AY V + +T+ E + + +VE++++ +VP++FVE+ ++ ++++T + Sbjct: 215 AYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPI 274 Query: 306 GGTLYSDALAPSGKPAATYLGMFEWNARQLSAAL 339 +++D++A G+ +Y M ++N +++ L Sbjct: 275 YAKIFTDSVAEKGEEGDSYYSMMKYNLEKIAEGL 308
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 169 bits (429), Expect = 6e-52 Identities = 83/353 (23%), Positives = 132/353 (37%), Gaps = 46/353 (13%) Query: 1 MSILVTGGAGFIGSNFVLAWLGGSDEPVINLDKLTYAGHAGNLD----SLQGDARHQLVH 56 M LVTG AGFIG + L + V+ +D L + +L L Q Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLN-DYYDVSLKQARLELLAQPGFQFHK 58 Query: 57 GDIADNALVAALLQAHQPRAVLNFAAESHVDRAIRGPDAFIHTNVTGTFQLLEAVRAYWQ 116 D+AD + L + V V ++ P A+ +N+TG +LE R Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 117 ALGEPARTGFRYLQVSTDEVYGSLGPQDPPFAEGDPY-RPNNPYSASKAAGDHLVRAYWH 175 L S+ VYG + PF+ D P + Y+A+K A + + Y H Sbjct: 119 Q---------HLLYASSSSVYGL--NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH 167 Query: 176 TYGLPVLTTHCPNNYGPRQFPEKLIPLLIHHALAGRPLPLYGDGSHVRDWLHVDDHCAGL 235 YGLP YGP P+ + L G+ + +Y G RD+ ++DD + Sbjct: 168 LYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 236 RRVLEAGE------------------PGQVYHVGAGQERSNLQVAQAVCALLDAWRPRAD 277 R+ + P +VY++G S +++ + AL DA A Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNS---SPVELMDYIQALEDALGIEAK 284 Query: 278 GRAHGEQITFVQDRPGHDRRYAIDAGKIRRQLGWQPAHAFDAGLRATVQWYLD 330 + +PG + D + +G+ P G++ V WY D Sbjct: 285 -------KNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 57.9 bits (140), Expect = 1e-11 Identities = 46/201 (22%), Positives = 76/201 (37%), Gaps = 37/201 (18%) Query: 21 MKILLLGATGQIGNALRRTLLPLG-------SITA-------PSRAQ-----------AD 55 MK L+ GA G IG + + LL G ++ +R + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 56 LANLDGLRALLQAQVPDLIVNAAACTAVDQAENDPAPARRVNAEAVAVLAAHARKSG-AL 114 LA+ +G+ L + + + + AV + +P N + R + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 115 LVHYSTDYVFDGAKQTPYLETD-APHPLNEYGRSKLAGE-QAIAAS---GCRALVLRTSW 169 L++ S+ V+ ++ P+ D HP++ Y +K A E A S G A LR Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 170 VYAAHGR------NFVKTVLQ 184 VY GR F K +L+ Sbjct: 181 VYGPWGRPDMALFKFTKAMLE 201
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 32.1 bits (73), Expect = 0.003 Identities = 33/154 (21%), Positives = 53/154 (34%), Gaps = 12/154 (7%) Query: 75 IDASSGQVLAAANPDMQIEPASLTKIMTAYVVFNALKEKRITLEQQVPVSEHAWRTGGSR 134 +D +SG+ L A D + S K++ V + LE+++ + Sbjct: 45 MDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPV 104 Query: 135 MFIEPRKPVTVDELIQGMIVQSGNDASVALAEAVGGSESAFAALMNQEAERLGLKRTHF- 193 +TV EL I S N A+ L VGG + ++G T Sbjct: 105 SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLD 159 Query: 194 -----MNATGLPDPQHVTTVADLA-VLSAALIND 221 +N D + TT A +A L L + Sbjct: 160 RWETELNEALPGDARDTTTPASMAATLRKLLTSQ 193
>PF03309#Bvg accessory factor Length = 271 Score = 89.4 bits (222), Expect = 3e-23 Identities = 43/210 (20%), Positives = 74/210 (35%), Gaps = 25/210 (11%) Query: 1 MILLIDSGNSRLKVGWLDNGAREPAAVAFDNL--DPHALGDWLGTLSRKPTLALGVNVAG 58 M+L ID N+ VG + V + +P D L +G + Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDG---LIGDDAER 57 Query: 59 AERG----------EGIRAALAGHGCPVHWITSRPQL-LGLRNGYTQPAQLGADRLVSLL 107 +R L + V + P + G+ P ++GADR+V+ L Sbjct: 58 LTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCL 117 Query: 108 GVRSRLAQTHPPFVLASFGTATTIDTVGPDNAFAGGLILPGPALMRSSLARGTANLPLAD 167 + ++ FG++ +D V F GG I PG + + A +A L + Sbjct: 118 AAYHKYGT---AAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVE 174 Query: 168 ----GPVVDFPVDTHQAIASGIAAAQAGAV 193 V+ +T + + +G AG V Sbjct: 175 LTRPRSVIGK--NTVECMQAGAVFGFAGLV 202
>PF04183#IucA / IucC family Length = 580 Score = 28.3 bits (63), Expect = 0.047 Identities = 15/65 (23%), Positives = 25/65 (38%), Gaps = 6/65 (9%) Query: 25 HIGAIEKHQDRAELVEICDTNPAALKAAHEATGARPFESLSDLLAESTADAVVLATPSGL 84 H A+++ ++ CD + A + F S + E+ D L P + Sbjct: 167 HWLAVKREH----MIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLP--V 220 Query: 85 HPWQA 89 HPWQ Sbjct: 221 HPWQW 225
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.1 bits (73), Expect = 0.005 Identities = 12/62 (19%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 291 LYDQIAKREVPALLGAADIGYISL-KPERLFRFGVSPNKLFDYMLARLPVLFAVRAGNNP 349 + D +A L +G + L + R + + L Y L + V+ ++ N+ Sbjct: 154 ISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQ 213 Query: 350 VA 351 +A Sbjct: 214 IA 215
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 37.1 bits (86), Expect = 1e-04 Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 4/129 (3%) Query: 289 NIMITGAGGSIGSELCRQILELRPRRMVLFEISEPALYTIEQELTTLRNTAGSEVEIIGV 348 ++TGA G IG + +++LE ++V + Y + L R ++ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLE-AGHQVVGIDNLNDY-Y--DVSLKQARLELLAQPGFQFH 57 Query: 349 LGSVRDYEHCLLQLRRHGIQTVYHAAAYKHVPIVEHNIAEGILTNTFGTHAMARAAIKVG 408 + D E + V+ + V N +N G + Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 409 VQDFVLIST 417 +Q + S+ Sbjct: 118 IQHLLYASS 126
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 26.7 bits (59), Expect = 0.008 Identities = 9/31 (29%), Positives = 17/31 (54%) Query: 1 MLKEGETGVPVADLCRKHGISNATYYQWKSK 31 ++K G P+ D R H +SN++ Y+ + Sbjct: 128 LIKNGSHSRPLTDFARSHFLSNSSAYRMREA 158
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 224 bits (572), Expect = 9e-68 Identities = 112/463 (24%), Positives = 203/463 (43%), Gaps = 54/463 (11%) Query: 9 RRRTFAIISHPDAGKTTLTEKLLLFAGAIQIAGSVKARKASRHASSDWMEIEKQRGISVA 68 + +++H DAGKTTLTE LL +GAI GSV +D +E+QRGI++ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTR----TDNTLLERQRGITIQ 57 Query: 69 SSVMQMEYRDCVINLLDTPGHQDFSEDTYRVLTAVDAALMVIDAANGVEPQTIRLLQVCR 128 + + ++ + +N++DTPGH DF + YR L+ +D A+++I A +GV+ QT L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 129 ARNTPIITFINKMDREVREPLDLLSEIEGHLGMDAVPFSWPVGMGKSFGGVFDIRRDRMR 188 P I FINK+D+ + + +I+ L + V V + M Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVI-KQKVELYP-----------NMC 165 Query: 189 VFRPGQERRSD-----DDDIIDG-LDNPEIASRFGSAFEQANGEIELIQEAAPAFDREAF 242 V + + D +DD+++ + + A E E Sbjct: 166 VTNFTESEQWDTVIEGNDDLLEKYMSGKSL-----EALELEQEESIRFHN---------- 210 Query: 243 LAGRQTPVFFGSAINNFGVQEVLDALVEQAPPPGPRQALERLVEPQEPKFTGVVFKVQAN 302 PV+ GSA NN G+ +++ + + R + + G VFK++ Sbjct: 211 --CSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHR---------GQSELCGKVFKIE-- 257 Query: 303 MDPAHRDRVAFVRVSSGRFERGMRLKVARTNKEMRPNNVVSFLSQRRELLDEAYAGDVIG 362 R R+A++R+ SG ++++ K + + + ++ +D+AY+G+ I Sbjct: 258 YSEK-RQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGELCKIDKAYSGE-IV 314 Query: 363 IPNHGVLQLGDVLTEGESLRFTGLPFFAPELFQ-AVEVKDPLRTKQLRIGLTQLGEEGAI 421 I + L+L VL + + L L Q VE P + + L L ++ + + Sbjct: 315 ILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPL 374 Query: 422 QVFRPEAAGGTLLLGAVGQLQFEVVAHRLKTEYGVEARMLPSR 464 + ++A ++L +G++Q EV L+ +Y VE + Sbjct: 375 LRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPT 417
>cloacin#Cloacin signature. Length = 551 Score = 38.5 bits (89), Expect = 2e-05 Identities = 19/32 (59%), Positives = 20/32 (62%) Query: 232 GGGGFGGGFGGGGGFGGGGGFGGGGGRSGGGG 263 GG G G +GGG G G GGG G GG SG GG Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 36.2 bits (83), Expect = 1e-04 Identities = 17/37 (45%), Positives = 20/37 (54%) Query: 229 GGRGGGGFGGGFGGGGGFGGGGGFGGGGGRSGGGGAS 265 GG G G G G G G GGG G GGG +GG ++ Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 34.7 bits (79), Expect = 4e-04 Identities = 17/37 (45%), Positives = 17/37 (45%) Query: 229 GGRGGGGFGGGFGGGGGFGGGGGFGGGGGRSGGGGAS 265 GG G G GG G G GG G GGG G G A Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAV 84 Score = 34.3 bits (78), Expect = 4e-04 Identities = 17/30 (56%), Positives = 18/30 (60%) Query: 237 GGGFGGGGGFGGGGGFGGGGGRSGGGGASG 266 GGG G G +GGG G G GGG GG SG Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSG 76 Score = 33.1 bits (75), Expect = 0.001 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 13/51 (25%) Query: 229 GGRGGGGFGGG-------------FGGGGGFGGGGGFGGGGGRSGGGGASG 266 GG G G GGG +GGG G G G G G G GG G SG Sbjct: 22 GGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72 Score = 32.8 bits (74), Expect = 0.001 Identities = 19/34 (55%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 233 GGGFGGGFGGGGGFGGGGGFGGGGGRSGGGGASG 266 GGG G G GGG G G G GG G SGGG +G Sbjct: 47 GGGSGSGIHWGGGSGHGNG--GGNGNSGGGSGTG 78 Score = 30.8 bits (69), Expect = 0.006 Identities = 16/34 (47%), Positives = 17/34 (50%) Query: 226 SRRGGRGGGGFGGGFGGGGGFGGGGGFGGGGGRS 259 S G GGG G G GGG G GGG GG + Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 30.5 bits (68), Expect = 0.007 Identities = 15/37 (40%), Positives = 15/37 (40%) Query: 230 GRGGGGFGGGFGGGGGFGGGGGFGGGGGRSGGGGASG 266 GGG G GG G GGG G GG A G Sbjct: 55 HWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFG 91 Score = 30.5 bits (68), Expect = 0.007 Identities = 13/36 (36%), Positives = 15/36 (41%) Query: 230 GRGGGGFGGGFGGGGGFGGGGGFGGGGGRSGGGGAS 265 G G GG G GG G G G G G + A+ Sbjct: 51 GSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAA 86
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.002 Identities = 17/87 (19%), Positives = 35/87 (40%), Gaps = 19/87 (21%) Query: 377 RVLVTAERDSDGAGRLAIHVDDDGAGIAATERERIFQRGVRMDEQRPGSGLGLDIVRD-L 435 ++L+ +D G + + V++ G + + + +G GL VR+ L Sbjct: 280 KILLKGTKD---NGTVTLEVENTG--------------SLALKNTKESTGTGLQNVRERL 322 Query: 436 ACTYGGDVQAG-ASPLGGLRITLLLPA 461 YG + Q + G + +L+P Sbjct: 323 QMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 1e-21 Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 1/120 (0%) Query: 2 RVLLIEDEPTLAAQLEQALRAAGYTVDRAADGQTAHYLGDVEAFDAVVLDLGLPVLDGLT 61 +L+ +D+ + L QAL AGY V ++ T D VV D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRRWRAAGRNMPVLILTARDSWHEKVAGIDAGADDYLAKPFHMEELLARV-RALIRRNS 120 +L R + A ++PVL+++A++++ + + GA DYL KPF + EL+ + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 28.7 bits (64), Expect = 0.038 Identities = 14/53 (26%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 308 YRAGGRIAMGTDAGTPFNRHGRNAEELAYMVAFGMTPADALVAGTSRAHELLG 360 YR G ++ +GT ++ +L +M G + D L A ++ +H LG Sbjct: 93 YRDGAKVHLGTRPDEK--QYDTVETQLRFMTENGFSLRDGLYAISAVSHFTLG 143
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 500 bits (1289), Expect = 0.0 Identities = 248/347 (71%), Positives = 293/347 (84%), Gaps = 1/347 (0%) Query: 1 MFGFLRSYFSSDMAIDLGTANTLIYVRGKGIVLDEPSVVAIRHEGGPNGKKIIQAVGHEA 60 M R FS+D++IDLGTANTLIYV+G+GIVL+EPSVVAIR + + K + AVGH+A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVA-AVGHDA 59 Query: 61 KQMLGRVPGNIEAIRPMKDGVIADFTVTEQMLKQFIRMVHPRNMLAPSPRIIVCVPCGST 120 KQMLGR PGNI AIRPMKDGVIADF VTE+ML+ FI+ VH + + PSPR++VCVP G+T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIRESALGAGASHVYLIEEPMAAAIGAGLAVSDASGSMVVDIGGGTTEVAVISLG 180 QVERRAIRESA GAGA V+LIEEPMAAAIGAGL VS+A+GSMVVDIGGGTTEVAVISL Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GMVYKGSVRVGGDKFDEAIVNYIRRNYGMLIGEPTAELIKKEIGSAFPGSEVREIEVKGR 240 G+VY SVR+GGD+FDEAI+NY+RRNYG LIGE TAE IK EIGSA+PG EVREIEV+GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPRSFTVSSNEILESLTDPLNQIVSAVKIALEQTPPELGADITDKGIALTGGGAL 300 NLAEGVPR FT++SNEILE+L +PL IVSAV +ALEQ PPEL +DI+++G+ LTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLLQEETGLPVVVAEDPLTCVVRGCGEALEHLEKLGAIFIND 347 LR+LDRLL EETG+PVVVAEDPLTCV RG G+ALE ++ G ++ Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSE 346
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.5 bits (84), Expect = 2e-04 Identities = 15/67 (22%), Positives = 19/67 (28%), Gaps = 1/67 (1%) Query: 619 PIPPAADSSEDAPATSGPAPAATAAPVPVTAAPPAPEPAPRPRPAPRATPAPKPPAMPSR 678 + P P P P P AP P+P+P P+ P K P R Sbjct: 54 DLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP-VVIEKPKPKPKPKPKPVKKVQEQPKR 112 Query: 679 RAPSTAP 685 Sbjct: 113 DVKPVES 119 Score = 36.1 bits (83), Expect = 3e-04 Identities = 21/89 (23%), Positives = 28/89 (31%), Gaps = 1/89 (1%) Query: 616 PVGPIPPAADSSEDAPATSGPAPAATAAPVPVTAAPPAPEPAPRPRPAPRATPAPK-PPA 674 P PP E P APV + P P+P P+P + P P Sbjct: 58 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPV 117 Query: 675 MPSRRAPSTAPALSDLTDLFQSPATGDKP 703 +P A + LT + AT Sbjct: 118 ESRPASPFENTAPARLTSSTATAATSKPV 146 Score = 31.9 bits (72), Expect = 0.007 Identities = 18/54 (33%), Positives = 20/54 (37%), Gaps = 7/54 (12%) Query: 630 APATSGPAPAATAAPVPVTAAPPAPEP-------APRPRPAPRATPAPKPPAMP 676 PA P A P PV P PEP AP P+ P PKP + Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 104 Score = 30.7 bits (69), Expect = 0.015 Identities = 16/50 (32%), Positives = 21/50 (42%) Query: 636 PAPAATAAPVPVTAAPPAPEPAPRPRPAPRATPAPKPPAMPSRRAPSTAP 685 PAPA + VT A P A +P P P P P+P +P + Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 88
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.2 bits (122), Expect = 3e-10 Identities = 30/181 (16%), Positives = 62/181 (34%), Gaps = 10/181 (5%) Query: 1 MASKPGERKTQILQTLAEMLEQPHAARITTAALAARMQVSEAALYRHFASKAQMFEGLIE 60 + E + IL + Q + + +A V+ A+Y HF K+ +F + E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 FIEVSLFTLVNQIAAAEPHGLGQARKTVSMLLAFSERNKGMTRVLTGDALVTEDNRLQER 120 E ++ L + A+ G + ++ R L + + + + E Sbjct: 65 LSESNIGELELEY-QAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 121 ------INHINDRIEASLKQSLRVAVSDGDLAPDANISAHASLLTHLVLG---RWLRYAQ 171 ++ ++Q+L+ + L D A ++ + G WL Q Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 172 S 172 S Sbjct: 184 S 184
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 39.0 bits (91), Expect = 1e-05 Identities = 27/129 (20%), Positives = 53/129 (41%), Gaps = 23/129 (17%) Query: 154 EPIDIGFVGDITQVEPAVVKALQDDQFIPVISPIGYG----EDGTAYN-----INADVVA 204 +P VE +K L + I VI+ G G + I+ D+ Sbjct: 169 DPKGH--------VEAETIKKLVERGVI-VIASGGGGVPVILEDGEIKGVEAVIDKDLAG 219 Query: 205 GKMAEVLGAEKLLMMTNTPGVLDKSGK----LLRSLSAQTIDELFADGT-ISGGMLPKIA 259 K+AE + A+ +++T+ G G LR + + + + + +G +G M PK+ Sbjct: 220 EKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVL 279 Query: 260 SSLDAAKNG 268 +++ + G Sbjct: 280 AAIRFIEWG 288 Score = 36.0 bits (83), Expect = 1e-04 Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 10/56 (17%) Query: 32 GKTIVVKYGGNAMTEERLQRSFAHDVVLLKLV----------GLNPVVVHGGGPQI 77 GK +V+ GGNA+ + + S+ + ++ G V+ HG GPQ+ Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQV 57
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.9 bits (62), Expect = 0.043 Identities = 40/190 (21%), Positives = 61/190 (32%), Gaps = 43/190 (22%) Query: 60 SLRHYWPQQWDGVDFSMDQHVDDLLAFIDTVGE--GAAHV--VGHSRGARVALEAALRAP 115 SL++YW Q+ D LA ID G V +G+S GA V P Sbjct: 86 SLKYYWKQK------DPKDVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMP 139 Query: 116 ARVRSLTLADPGLPMPGREGD------TRGGFRQRALALIEAGEVDAGLALFVDTVSGAD 169 AR R + L P + D ++ + EV+ + + + G + Sbjct: 140 ARYRK-NVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLTLPEVNKQTTVPMLCLYGKE 198 Query: 170 TWRRMVPWFKDMVRDNASTLGGQATEHL-PPVPREQVERLALPTLLIGGALSPAPYPAVL 228 A HL P V + V + L GG Y V+ Sbjct: 199 D---------------------DAPLHLCPEVKQPNVTVMELS----GGHSFDDDYDKVV 233 Query: 229 DMLAEWLPAA 238 ++ WL + Sbjct: 234 KLIKGWLKPS 243
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 91.9 bits (228), Expect = 8e-25 Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 11/114 (9%) Query: 62 SVYFDFDSYTVPDQYRGLVETHARYLASH--QQQRVQIQGNTDERGGAEYNLALGQRRAD 119 V F+F+ T+ + + ++ L++ + V + G TD G YN L +RRA Sbjct: 220 DVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQ 279 Query: 120 AVRRMMTLLGVSDAQIETISFGKEKPRATGTTE---------ADFAENRRADIE 164 +V + G+ +I G+ P T + A +RR +IE Sbjct: 280 SVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 68.6 bits (167), Expect = 2e-14 Identities = 36/205 (17%), Positives = 61/205 (29%), Gaps = 25/205 (12%) Query: 67 PPPDVQPDEPKPEPEPPKPQPQPEPAPQPEPQPQPEPPPPPPPPVEKPQPPQPDPEIALE 126 ++ P P E A P PPP P P E + Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIA---RVDEAPVPPPAPATPSETTE---------TV 1040 Query: 127 EARKKREEEEKARQEAEAAKEKARLEEERKQAELKEKQRLEQERKAAEKAAAEKAAAEKA 186 K+E + + E +A + A+ ++ + K ++ + E A + E Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQ----NREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 187 AAEKAAAEKAAAEKAAAEKAAAEKAAAEKKAKEEAAKKAAAEKAAAEKAAAEKAAAEKAA 246 E K A EKA E + +E K + E++ + AE A Sbjct: 1097 TTET---------KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 247 AEKAAAEKKAKEEAAKKAAAAKKAA 271 K + A ++ A Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPA 1172 Score = 56.6 bits (136), Expect = 1e-10 Identities = 38/226 (16%), Positives = 62/226 (27%), Gaps = 24/226 (10%) Query: 62 DTPDSPPPDV----QPDEPKPEPEPPKPQPQPEPAPQP-EPQPQPEPPPPPPPPVEK--- 113 DT + P+ P P E + P P P P P E K Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVE 1052 Query: 114 -----PQPPQPDPEIALEEARKK----REEEEKARQEAEA-------AKEKARLEEERKQ 157 +EA+ + E A+ +E KE A +E+E K Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 158 AELKEKQRLEQERKAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKKA 217 EK + + + E++ + AE A + A E+ A Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 218 KEEAAKKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKKAKEEAAKK 263 KE ++ + A + E++ K Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Score = 52.8 bits (126), Expect = 2e-09 Identities = 28/149 (18%), Positives = 42/149 (28%), Gaps = 5/149 (3%) Query: 134 EEEKARQEAEAAKEKARLEEERKQAELKEKQRLEQERKAAEKAAAEKAAAEKAAAEKAAA 193 E EK Q + + E+ + E A A + + A Sbjct: 984 EVEKRNQTVDT--TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 194 EKAAAEKAAAEKA---AAEKAAAEKKAKEEAAKKAAAEKAAAEKAAAEKAAAEKAAAEKA 250 E + E EK A E A ++ +EA A E A + E E Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 251 AAEKKAKEEAAKKAAAAKKAAADKALREA 279 KEE AK + + + Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVS 1130 Score = 46.6 bits (110), Expect = 2e-07 Identities = 26/176 (14%), Positives = 49/176 (27%), Gaps = 23/176 (13%) Query: 69 PDVQPDEPKPEPEPPKPQPQPEPAPQPEP------------------QPQPEPPPPPPPP 110 P V + + QPQ EPA + +P QP E P Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQP 1182 Query: 111 VEKPQPPQPDPEIALEEARKKREEEEKARQEAEAAKEKARLEEERKQAELKEKQRLEQER 170 V + + + E A + E + + R + ++ + Sbjct: 1183 VTESTTVNTGNSVV-----ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA 1237 Query: 171 KAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKKAKEEAAKKAA 226 + + A + + A A KA KA ++ ++ E + Sbjct: 1238 TTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 44.7 bits (105), Expect = 5e-07 Identities = 26/220 (11%), Positives = 60/220 (27%), Gaps = 13/220 (5%) Query: 72 QPDEPKPEPEPPKPQPQPEPAPQPEPQPQPEPPPPPPPPVEKPQPP---QPDPEIALEEA 128 + PK + Q Q E +PQ +P P +++PQ D E +E Sbjct: 1119 TQEVPKVTSQVSPKQEQSETV---QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 129 RKKREEEEKARQEAEAAKEKARLEEERKQAELKEKQRLEQERKAAEKA--AAEKAAAEKA 186 E+ E A + E K + + Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Query: 187 AAEKAAAEKAAAEKAAAEKAAAEKAAAEKKAKEEAAKKAAAEKAAAEKAAAEKAAAEKAA 246 A ++ +++ ++ +AK + + + + E + Sbjct: 1236 PATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Query: 247 AEKA-AAEKKAKEEAAKKAAAAKKAAA----DKALREAFR 281 + + K + + ++K D+ + + Sbjct: 1296 VWVSNTSMNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQ 1335 Score = 38.9 bits (90), Expect = 3e-05 Identities = 31/210 (14%), Positives = 58/210 (27%), Gaps = 8/210 (3%) Query: 59 AEGDTPDSPPPDVQPDEPKPEPEPPKPQPQPEPAPQPEP-QPQPEPPPPPPPPVEKPQPP 117 E T ++ E K + E K Q P+ Q P Q Q E P P Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP-----AR 1147 Query: 118 QPDPEIALEEARKKREEEEKARQEAEAAKEKARLEEERKQAELKEKQRLEQERKAAEKAA 177 + DP + ++E + + Q A+ +E Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 178 AEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKAAAEKKAKEEAAKKAAAEKAAAEKAAA 237 +E + K ++ + A ++ ++ + A A Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPAT--TSSNDRSTVALCDLTSTNTNAVLSDAR 1265 Query: 238 EKAAAEKAAAEKAAAEKKAKEEAAKKAAAA 267 KA KA ++ ++ E + Sbjct: 1266 AKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 28.8 bits (64), Expect = 0.009 Identities = 18/120 (15%), Positives = 45/120 (37%), Gaps = 25/120 (20%) Query: 20 VVPYIDVMLVLLVIFMVTAPLITPGLINLPSVGQASEVPATPLEVQISEDGQVALRMREA 79 ++ +LVL+V +++ + P L E A + Q+ ++ + Sbjct: 458 LLAAGRWLLVLVVAWILWRKAVRPQLTRR-----VEEAKAAQEQAQVRQETEE------- 505 Query: 80 GATPQDIARDQLVDQVRQRITAETPVVIAADGKVPYETVVKVMDELRSNGVTRLGLLVDQ 139 A +++D+ + Q R ++ E + + + E+ N + L++ Q Sbjct: 506 -AVEVRLSKDEQLQQRRANQ------------RLGAEVMSQRIREMSDNDPRVVALVIRQ 552
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 6e-23 Identities = 35/143 (24%), Positives = 66/143 (46%), Gaps = 2/143 (1%) Query: 2 RILLVEDELEMASWLVRALAQSGFTPDHAPDARSAEALMAANEYDAIVMDLRLPDKHGLV 61 IL+ +D+ + + L +AL+++G+ +A + +AA + D +V D+ +PD++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRDMRGRDDRTPVLLLTAQGALQDRVRGLNLGADDFLTKPFALEELEARVAALVRRSRG 121 +L ++ PVL+++AQ ++ GA D+L KPF L EL + + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 RQFPRLQCGSLAYD--GESRAFT 142 R G S A Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQ 147
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 9/40 (22%), Positives = 15/40 (37%), Gaps = 4/40 (10%) Query: 393 LVHNAIHYA----PAGARITVSVARRGSRAEVAVSDNGPG 428 LV N I + P G +I + + + V + G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 30.4 bits (68), Expect = 0.009 Identities = 13/65 (20%), Positives = 26/65 (40%), Gaps = 7/65 (10%) Query: 140 FKFGPAEYFSLMTLGLVGAVVLASGSLPKAIAMIILGLLLGMVGTDVNS--GVARYDFGI 197 F G + L+ + ++G VVL LP A+ + + + + + + + Sbjct: 2 FDIG---FSELLLVFIIGLVVLGPQRLPVAVKTV--AGWIRALRSLATTVQNELTQELKL 56 Query: 198 PELQD 202 E QD Sbjct: 57 QEFQD 61
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.022 Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 15/90 (16%) Query: 37 MGPGYFPFALGLVLAILGAIV--------LLGSMTKSATETHVDK-------FDWRIAFL 81 G Y F++ +V A+ +++ L ++ K + H + F+ Sbjct: 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHS 522 Query: 82 VIGSVILYGLILKLLGIYISVFVLVVVSSL 111 V G IL G Y+ ++ L+V + Sbjct: 523 VNHYTNSVGKILGSTGRYLLIYALIVAGMV 552
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.012 Identities = 19/143 (13%), Positives = 44/143 (30%), Gaps = 17/143 (11%) Query: 3 QDLDQLAARIGQLVQRTRQLHAERDALRVRLSQSESSQRALEQRCADHQA---------- 52 + + Q + AER + R+++ E+ R + R D + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 53 EIQALQAKLQEHDSAVAGMLNEARQTESDLREQLARATADRQSLES-------RASAREA 105 + + K E + + ++ Q ES++ Q ++ + + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 106 ELQGSLHARDTDLQRLRVAASAA 128 L L + Q + A + Sbjct: 313 LLTLELAKNEERQQASVIRAPVS 335
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.017 Identities = 10/49 (20%), Positives = 21/49 (42%), Gaps = 5/49 (10%) Query: 31 QRHLSAEDVYRALIGENVEIG----LATVYRVLTQFEQAGILSRSQFDS 75 + L+ DV L +N +I T Q + I+++++F + Sbjct: 195 KYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS-IIAQTRFKN 242
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 32.0 bits (72), Expect = 0.008 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 4/122 (3%) Query: 260 LQGVADELESARIAVSEAVSDL---NNYVSRVDLDPQRLAEVETRMSAVFETARKFKTEP 316 L+ + +E + + + ++L NN + + + RLA+ E + E A K E Sbjct: 94 LKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEA 153 Query: 317 EALPALRESVQAQLAD-LQAAADIDALRARADAAAAQYETAAGKLSAARARVAKSLGKQV 375 E E +A+ L+ A + A A E A KLSAA++ V K G+ Sbjct: 154 EQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIK 213 Query: 376 TQ 377 T Sbjct: 214 TL 215
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 35.2 bits (81), Expect = 2e-04 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 14/102 (13%) Query: 69 DTASNTGVHEYPVATLQEIGATAS-----LAVVMGGDGTVL----GAARTLAPYGVPLVG 119 + A N G+ PV ++ A +S L + + GDG L G P+VG Sbjct: 24 EFADNLGLTLLPVEPSTQVNAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWPVVG 83 Query: 120 INHGRLGFITDVPLQEAHIALARVIEGNYQAE---DRMLLVG 158 + + + ++ +I+ YQAE +++L+G Sbjct: 84 WSSLKY-YWKQKDPKDVTQDTLAIID-KYQAEFGTQKVILIG 123
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.1 bits (127), Expect = 5e-11 Identities = 30/180 (16%), Positives = 64/180 (35%), Gaps = 3/180 (1%) Query: 1 MARPREFDETAVLDAAVRCFWARGFEATSVRELAESMGITGASLYNAFGDKRSLYRRALD 60 + + +LD A+R F +G +TS+ E+A++ G+T ++Y F DK L+ + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 HYVETSFSARARRVESLP--PSEALAAFFADIVERSLADRQRKGCMIINSALEVAPHD-P 117 P P L ++E ++ + +R+ M I + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 118 EFQQVVVSVLGRIEAFFLRCVTTGQQAGTIITTQPADDLARLLLSVLMGVRVMARARPER 177 QQ ++ + + +A + A ++ + G+ P+ Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.3 bits (65), Expect = 0.035 Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 5/101 (4%) Query: 81 GGYLGALAAWAGFTLPSAALLVLFALGISHFGQALAPGVLHGLKVVAVAVVAQAVWNMAR 140 GG ALAA G + A +V A G+S QAL P + H LK + + ++ +A+ Sbjct: 337 GGASLALAA-VGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPL-MELIGKAITKALE 394 Query: 141 SLCADARRA---GIMVAAACAASLLPYAWTQIGILAAAAVA 178 L D + A G +V A AA + + ++ A A Sbjct: 395 GLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAA 435
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.011 Identities = 19/103 (18%), Positives = 38/103 (36%), Gaps = 21/103 (20%) Query: 361 IATLVDNALKYA----GDAARIRIETVQTDRETRLTVADNGPGIPAAKMDRIGERFYRAH 416 + TLV+N +K+ +I ++ + + L V + G + E Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL----ALKNTKE------ 309 Query: 417 RHVPGYGLGLATVMA-IARLHGG--RLELSNAEPGLCVRLHFP 456 G GL V + L+G +++LS + + + P Sbjct: 310 ----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 6e-17 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 1/132 (0%) Query: 3 RCLIVEDDADNARYIANGLKELGYDPVITMDGPTALQRATTEHWDAIILDRMLPNDVDGL 62 L+ +DDA + L GYD IT + T + D ++ D ++P D + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMP-DENAF 63 Query: 63 SILWSLRALGRKTPVLVLSALTALDERVRGLKAGGDDYLTKPFAFPELAARVEALIRRSS 122 +L ++ PVLV+SA ++ + G DYL KPF EL + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 SGYERRQLTVAD 134 + + D Sbjct: 124 RRPSKLEDDSQD 135
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (283), Expect = 2e-32 Identities = 69/261 (26%), Positives = 114/261 (43%), Gaps = 12/261 (4%) Query: 2 LKGKVAIVTGSTSGIGLGIATAFAQQGADIVLNGFGDAAEIEKLRAGLASQHGVKVLYDG 61 ++GK+A +TG+ GIG +A A QGA I E + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA--AVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 ADLSRGEAVRQLVANTVQSLGRVDILVNNAGIQHTALIEDFPVEKWDAILALNLSAVFHG 121 AD+ A+ ++ A + +G +DILVN AG+ LI E+W+A ++N + VF+ Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 TAAALPHMKKQGWGRIINIASAHGLVGSANKSAYVAAKHGVVGLTKVTALETAGSGITAN 181 + + +M + G I+ + S V + +AY ++K V TK LE A I N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 182 AICPGWVRTGLVEKQITALAEKDHVDQ----DAAARKLLSEKQPSLQFVTPEQLGGTAVY 237 + PG T + Q + A+++ +Q K P + P + ++ Sbjct: 184 IVSPGSTETDM---QWSLWADENGAEQVIKGSLETFKT---GIPLKKLAKPSDIADAVLF 237 Query: 238 LASDAAAQVTGTSISVDGGWT 258 L S A +T ++ VDGG T Sbjct: 238 LVSGQAGHITMHNLCVDGGAT 258
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 5e-04 Identities = 31/168 (18%), Positives = 64/168 (38%), Gaps = 13/168 (7%) Query: 30 PYLTQELNLSAADLGSLTSLYFLGFALMQLPAGLFLDTWGPRRVNALMLLLAAAGTLVYG 89 P + + N A + + + L F++ G D G +R+ +++ G+++ Sbjct: 38 PDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGF 97 Query: 90 LSDS-LPGLMAGRLLIGAGVCVCLGAAFQAL-----AQTFPLARLPMVNGLVMAVGGLGG 143 + S L+ R + GAG AAF AL A+ P GL+ ++ +G Sbjct: 98 VGHSFFSLLIMARFIQGAG-----AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE 152 Query: 144 VLVGSPLSWLLERSSWQSVSIGLAFFTLTVAALIWFGAPREGARHRST 191 + + + W + + +TV L+ ++ R + Sbjct: 153 GVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKL--LKKEVRIKGH 198
>cloacin#Cloacin signature. Length = 551 Score = 35.1 bits (80), Expect = 1e-04 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 5/66 (7%) Query: 27 PDGKGKPAQAGHGNG-----NGNGSGNGSGNGKSGNSGGNPGNGNGGTKGSRGGDDINVS 81 P G G A G+G N G G+GSG G SG G GNG + G G + Sbjct: 24 PTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Query: 82 VSLATA 87 V+ A Sbjct: 84 VAAPVA 89 Score = 33.1 bits (75), Expect = 5e-04 Identities = 21/74 (28%), Positives = 27/74 (36%) Query: 40 NGNGNGSGNGSGNGKSGNSGGNPGNGNGGTKGSRGGDDINVSVSLATAGISIAAARGYAA 99 G G+GSG G G +GG GN GG+ + V+ +S A G A Sbjct: 46 WGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAV 105 Query: 100 DYGLTGYSALPPGI 113 SA I Sbjct: 106 SISAGALSAAIADI 119
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.8 bits (67), Expect = 0.011 Identities = 21/157 (13%), Positives = 39/157 (24%), Gaps = 25/157 (15%) Query: 63 TEELSHLEVIGTLVAMLNKGAKGELAEATESEADLYRSLHGAGND-SHVTQVLYGGGPAL 121 EL + + L+++L+ L+ L L G + S ++L G Sbjct: 94 VPELEQKQNVSELLSLLSNSPNISLS-------QLKAYLEGKSEEPSEQFKMLCG---LR 143 Query: 122 TNSGGQLWNAGYIDTIGDPSADLRSNIAAEARAKIVYERLINVTE--------DPGVKEA 173 G+ A + + +T + Sbjct: 144 DALKGRPELAHLSHLVEQALVSMAEEQGETIVLGA------RITPEAYRESQSGVNPLQP 197 Query: 174 LGFLMTREVSHQRSFEKALYSMQPNFPPGKLPGDPRF 210 L V + +Q FP G + F Sbjct: 198 LRDTYRDAVMGYQGIYAIWSDLQKRFPNGDIDSVILF 234
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 29.7 bits (66), Expect = 0.014 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%) Query: 74 LTLGLVAAGAMLAAGSGMAQPQPTTPAPATQDAAAEQQLDSSDKDFLENAAQSGHAEVEG 133 +++G +AAG A +G+AQ TP P ++D D NAA+S + Sbjct: 236 VSVGAIAAGLAGLAATGIAQALALTPEPDDP--------TTTDPDQAANAAESATKD--- 284 Query: 134 SKMAQEKAKNPD 145 ++ QE KNP+ Sbjct: 285 -QLTQEAFKNPE 295
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 92.8 bits (230), Expect = 1e-24 Identities = 75/264 (28%), Positives = 116/264 (43%), Gaps = 12/264 (4%) Query: 4 AAELQGRCALVTGSTASLGLAIADRLAAAGARI--VLHNLLADEPARQARDALARRHGTD 61 A ++G+ A +TG+ +G A+A LA+ GA I V +N E + A AR H Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEA 61 Query: 62 VLLQAADLNEVDQIEAMAHEARHAFGGIDIVVNNAVVRHFGPADTLPRNQWDEALAVNVS 121 D +D+I A G IDI+VN A V G +L +W+ +VN + Sbjct: 62 FPADVRDSAAIDEITARIERE---MGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNST 118 Query: 122 AAFHLARLSIPGMRSRGWGRIINMSSVYGSGATANRVGYITTKTALIGLTRALAVETAQD 181 F+ +R M R G I+ + S + Y ++K A + T+ L +E A+ Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 182 GITCNAVAPGTVPTPTIASRIAGIARDQGISEQQAQHDYLAHRQ--PTGRFVDMANVAAL 239 I CN V+PG+ T S A D+ +EQ + + P + +++A Sbjct: 179 NIRCNIVSPGSTETDMQWSLWA----DENGAEQVIKGSLETFKTGIPLKKLAKPSDIADA 234 Query: 240 IGFLCSDAGRDITGALLPIDGGWT 263 + FL S IT L +DGG T Sbjct: 235 VLFLVSGQAGHITMHNLCVDGGAT 258
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 29.3 bits (65), Expect = 0.014 Identities = 28/115 (24%), Positives = 39/115 (33%), Gaps = 5/115 (4%) Query: 37 RWAVAALLADARIGQVRVAVSPGDERAGAALAGLPRTVCRPCGG--PTRAATVAAALADS 94 R A A + A + R + GD AG A+ G GG P V Sbjct: 239 RAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGV 298 Query: 95 NAADSDWILVHDAAR-PGLPPDALARLIDACLADAVGGLLALPVADTVKAGGPRV 148 + + S L P L A R+ GG L+ P + ++ GG R Sbjct: 299 DVSGSSVELAQSIVEAPEL--GAAIRVGRGARVTVSGGSLSAPHGNVIETGGARR 351
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 1e-05 Identities = 18/104 (17%), Positives = 34/104 (32%), Gaps = 22/104 (21%) Query: 351 LIENARRYG-RSTDGLAHLKMTLQAEGSILVIEVSDRGPGIAPEEVDRLLRPFSRGEAAR 409 L+EN ++G + + + + +EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 410 TGVSGAGLGLAIVERLLKHVGG---SLKMLARPGGGLTARIEIP 450 G GL V L+ + G +K+ + G A + IP Sbjct: 310 ----STGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 102 bits (255), Expect = 4e-27 Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 1/135 (0%) Query: 11 KILVVDDDPRLRDLLRRYLSEQGFNVFVAEDAKEMGKLWQREHFDLLVLDLMLPGEDGLS 70 ILV DDD +R +L + LS G++V + +A + + DL+V D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 71 ICRRLRGGHDNTPIIMLTAKAEEIDRIVGLEMGADDYLSKPFNPRELLARI-NAILRRRG 129 + R++ + P+++++A+ + I E GA DYL KPF+ EL+ I A+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 130 TEEHPGAPSQENESI 144 SQ+ + Sbjct: 125 RPSKLEDDSQDGMPL 139
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 47.2 bits (112), Expect = 2e-08 Identities = 20/73 (27%), Positives = 33/73 (45%) Query: 326 IAVARQRHRQGLGSQLIDWCEQCARQRGLPALLLEVRPSNRGALAFYERRGFQRIGVRRG 385 IAVA+ ++G+G+ L+ + A++ L+LE + N A FY + F V Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTM 154 Query: 386 YYPAGQGQREDAL 398 Y E A+ Sbjct: 155 LYSNFPTANEIAI 167
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.1 bits (106), Expect = 3e-07 Identities = 30/114 (26%), Positives = 38/114 (33%), Gaps = 15/114 (13%) Query: 28 KTWLPAAEPATQ--PTRAATAPAAATATTPAAAAPMQEAARDGVAPVREQKPAPAGAPTP 85 +T P AEPA + PT P + T TT P +E + + PV E G Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 86 PRP------AARP-------NVPVPAAREQAQPAAQPVEPARDFDALREQVIQC 126 P +P N P R + VEPA R V C Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALC 1250 Score = 32.3 bits (73), Expect = 0.002 Identities = 17/104 (16%), Positives = 31/104 (29%), Gaps = 6/104 (5%) Query: 25 GIEKTWLPAAEPATQPTRAATAPAAATATTPAAAAPMQEAARDGVAPVREQKPAPAGAPT 84 G + P E Q + P A V E AP P Sbjct: 976 GRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI---ARVDE---APVPPPA 1029 Query: 85 PPRPAARPNVPVPAAREQAQPAAQPVEPARDFDALREQVIQCAA 128 P P+ ++++++ + + A + A +V + A Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAK 1073
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 51.6 bits (123), Expect = 2e-08 Identities = 54/328 (16%), Positives = 118/328 (35%), Gaps = 22/328 (6%) Query: 242 RRETENRLSDTRENLTRVEDILRELGSQLEKLEAQAEVARQYRELQADGEKKQFALWLLK 301 +E E R +D + L + ++++ LEA+ K L Sbjct: 115 IQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA--------RKADLEKALEG 166 Query: 302 ETGARDERQRKSQEMAQAQTNLEAAIANLRSGEAELESRRQAHYAAGDAVHAAQGQLYEA 361 K + + + LEA A L E LE A + + + Sbjct: 167 AMNFSTADSAKIKTLEAEKAALEARQAEL---EKALEGAMNFSTADSAKIKTLEAEKAAL 223 Query: 362 NAQVSRLEAEIRHVVDSRNRLQARREQLQQQIAEWDAQQTHCVEQIAQAEDDLATGAART 421 A+ + LE + ++ A+ + L+ + A +A+Q + + A + +A+ Sbjct: 224 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 422 EEARALAEEAHASLPAVEARVRDAAASRDEMRSSLARVEQNLALAAQTQRDADRQLQNLE 481 + A A +E + + A+R +R L + + + Q + E Sbjct: 284 KTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 343 Query: 482 QRRERLQQELRELHAPDPVRLEQLAGDRAAGEDQLEEAQQELAALEARVPEADAERSRAQ 541 R+ L+++ L+ + E + ++ +++ EA + ++ Sbjct: 344 ASRQSLRRD-----------LDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 392 Query: 542 AAAQQDAQNLARLEARLAALVKLQEDVQ 569 A +Q + L ++LAAL KL ++++ Sbjct: 393 EAKKQVEKALEEANSKLAALEKLNKELE 420 Score = 47.8 bits (113), Expect = 2e-07 Identities = 56/311 (18%), Positives = 108/311 (34%), Gaps = 37/311 (11%) Query: 718 DSEQAGLLARQQEIENLQREIKAQQLIADQARAAVARAESAWQQVSQAVAPARQRV---- 773 + G + + ++A++ +A + +A S A + + + Sbjct: 126 EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEK 185 Query: 774 AEITRRVHDIQLEHSRLQQQAEQSGERAARLRQDLEEISAHEEDLRATREEAEARFEALD 833 A + R +++ + + L + ++A + DL E A A Sbjct: 186 AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADS 245 Query: 834 AELAEHQSRFADAEIAGEDLAAQAEAARARL---------RELERAAQEAEFAERGVQSR 884 A++ ++ A E +L E A E E+AA EAE A+ QS+ Sbjct: 246 AKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQ 305 Query: 885 IADLQRNRQLAADQSQRAAVELEQLQADLADLD-----ASASQAGLQDALEVRAEREEAL 939 + + R + R A +QL+A+ L+ + AS+ L+ L+ EA Sbjct: 306 VLNANRQSLRRDLDASREA--KKQLEAEHQKLEEQNKISEASRQSLRRDLD---ASREAK 360 Query: 940 SRARQELDNLSALLRGADEERMQQERALEPLRARITELQLQEQAARLAEEQFTEQLNARE 999 + E L + ++ R R L+ A+R A++Q + L Sbjct: 361 KQLEAEHQKLEEQNKISEASRQSLRRDLD--------------ASREAKKQVEKALEEAN 406 Query: 1000 VDREALAQELA 1010 AL + Sbjct: 407 SKLAALEKLNK 417 Score = 47.8 bits (113), Expect = 3e-07 Identities = 53/359 (14%), Positives = 118/359 (32%), Gaps = 13/359 (3%) Query: 214 INRLIEARPEELRVFLEEAAGVSRYKERRRETENRLSDTRENLTRVEDILRELGSQLEKL 273 ++ E + + E+A+ + + R+ + E L T ++ L ++ L Sbjct: 94 LSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 153 Query: 274 EAQAEVARQYRE------LQADGEKKQFALWLLKETGARDERQRKSQEMAQAQTNLEAAI 327 A+ + E + K + E ++ + T A I Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213 Query: 328 ANLRSG----EAELESRRQAHYAAGDAVHAAQGQLYEANAQVSRLEAEIRHVVDSRNRLQ 383 L + A +A A + A ++ A+ + LEA + + Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAM 273 Query: 384 ARREQLQQQIAEWDAQQTHCVEQIAQAEDDLATGAARTEEARALAEEAHASLPAVEARVR 443 +I +A++ + A E A + R + + + +EA + Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333 Query: 444 DAAASRDEMRSSLARVEQNLALAAQTQRDADRQLQNLE---QRRERLQQELRELHAPDPV 500 +S + ++L + + ++ + + Q LE + E +Q LR Sbjct: 334 KLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE 393 Query: 501 RLEQLAGDRAAGEDQLEEAQQELAALEARVPEADAERSRAQAAAQQDAQNLARLEARLA 559 +Q+ +L ++ LE + E++ QA + +A+ L A+ A Sbjct: 394 AKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQA 452
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 30.3 bits (68), Expect = 0.016 Identities = 14/42 (33%), Positives = 18/42 (42%) Query: 281 TSDIGWVVGHSYIVYGPLIGGQTTILYEGTPVRPDGAILWRL 322 T DI H Y + +IG T+LY P + AI W Sbjct: 130 TQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYY 171
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 7/104 (6%) Query: 287 AAGAFAFGYLQDRIGHKRALGITLAGWIVMVLVAYAAVTAPVFWAAAILAGLCMGTSQSA 346 + G +G L D++G KR L L G I+ + F++ I+A G +A Sbjct: 63 SIGTAVYGKLSDQLGIKRLL---LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAA 119 Query: 347 GRAM----VGALAPPARLAEFFALWTFAVQLAAVVGPLTYGLVT 386 A+ V P + F L V + VGP G++ Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.0 bits (67), Expect = 0.015 Identities = 29/115 (25%), Positives = 39/115 (33%), Gaps = 3/115 (2%) Query: 91 GAAVLGSIQPQPIEHAADGTLPLDKLAAAVKPQGDPHFARTRLLALENTFQGKVIPAGYI 150 G +G++Q E + L P A + L A E T G I G Sbjct: 181 GGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGGHITGG-- 238 Query: 151 DQAAAFARQHGLGLHLDGARVFNAAVASGRPVQDVCAPFDSVSICFSKGLGAPVG 205 +AA A G +HL A + +G V P +V F G PV Sbjct: 239 -RAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVL 292
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 40.5 bits (95), Expect = 4e-06 Identities = 42/188 (22%), Positives = 69/188 (36%), Gaps = 30/188 (15%) Query: 4 RVLLAG-CGDLGLRLARRLLADGAEVWAL------------RRQPPANEPGGIHWLRADL 50 + L+ G G +G +++RLL G +V + + + G + + DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 51 TQPDTLAGLPA--GITQLAYLPA-PGAR----DPAVYQAVFREGLPALLAALDTRALQRV 103 + + L A ++ P R +P Y G +L +Q + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 104 LFVSSSAVYG-NHDGGWVDETTPPAPAGFNGRVLLDTENWLAAQA------LPSVSLRLA 156 L+ SSS+VYG N + + + P E L A LP+ LR Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE--LMAHTYSHLYGLPATGLRFF 179 Query: 157 GLYGP-GR 163 +YGP GR Sbjct: 180 TVYGPWGR 187
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 43.7 bits (103), Expect = 7e-07 Identities = 39/161 (24%), Positives = 62/161 (38%), Gaps = 22/161 (13%) Query: 96 CQLVAAAQQAGGEALPHALRDLAGAARLVQQARGTLAGT----CAAGGAALAVAVGLLCA 151 C +VAA + +G L L LA QQ R + C A+AV LL Sbjct: 136 CAMVAAGETSG--HLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSV 193 Query: 152 VPYFTVPRLQHVF----QAVPADYYGGLTQGLYALAQALRRWLAFWAVLLAGGAWLAAWS 207 V VP++ F QA+P T+ L ++ A+R + + + L G Sbjct: 194 V----VPKVVEQFIHMKQALPL-----STRVLMGMSDAVRTFGPWMLLALLAGFMAFRVM 244 Query: 208 L--PAFTGPWRARLDRL-VPWRLYRDFHAIRFLAMLAVMLR 245 L + RL L + R+ R + R+ L+++ Sbjct: 245 LRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNA 285
>PilS_PF08805#PilS N terminal Length = 185 Score = 41.1 bits (96), Expect = 7e-07 Identities = 32/192 (16%), Positives = 65/192 (33%), Gaps = 32/192 (16%) Query: 11 RRQAGFSLIEVSIVTAIVLLVAIIGIPAIGAYVIENKVPKVGEELQRFVARTKTFAQGSG 70 + G +L+EV +V +++++A + + +A K+ + G Sbjct: 23 EQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNNVLTVIANMKSL-KFQG 81 Query: 71 PAPYADIDTGALANALRDSSVVAVAGTGAAAVVSHGLGGSGSGSNGTITVAPAAVAGGGA 130 ++ L S + TGA+A G G++T+ + Sbjct: 82 RYTDSNY-IKTLYAQGLLPSDMIADTTGASAKNPWG---------GSVTITTS-----SD 126 Query: 131 GSGFVITLTNVSNAACPGLASVMQRVSDIITVEGRGGAAKVKDITIVPRLAYSAAAAESQ 190 F + NV C + + ++ I+ + + S +A + Sbjct: 127 KYSFNVVEANVPQKNCMAMVNALRS---------------SSAISKINNTSTSTVSAATV 171 Query: 191 CAEGDSNTFVFT 202 CA DSNT F+ Sbjct: 172 CA-SDSNTLTFS 182
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.6 bits (69), Expect = 0.004 Identities = 15/57 (26%), Positives = 27/57 (47%) Query: 15 RPGRRQAGFALLELTLAVALAGMLLVWGANRLVHRIDDAAGQATGAWMLELKRGLDN 71 R +Q GF LLE+ + + + G+L L+ + A Q + ++ L+ LD Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58
>PF01206#SirA family protein Length = 76 Score = 89.8 bits (223), Expect = 1e-27 Identities = 37/77 (48%), Positives = 53/77 (68%), Gaps = 2/77 (2%) Query: 10 LPEFQHEVDASGLTCPLPILRAKKALAQMESGQVLRVATTDPKATRDFQAFAKQSGNALL 69 + EF +DA+GL CPLPIL+AKK LA M +G+VL V TDP + +DF++F+KQ+G+ LL Sbjct: 1 MAEFDQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELL 60 Query: 70 AQHDNNQGTVLHFLRRR 86 Q + + HF +R Sbjct: 61 EQKE--EDGTYHFRLKR 75
>FLAGELLIN#Flagellin signature. Length = 507 Score = 249 bits (637), Expect = 6e-79 Identities = 236/507 (46%), Positives = 286/507 (56%), Gaps = 7/507 (1%) Query: 2 AAVINTNYLSLVAQNNLNKSQSALGSAIERLSSGLRINSAKDDAAGQAIANRFTANVRGL 61 A VINTN LSL+ QNNLNKSQS+L SAIERLSSGLRINSAKDDAAGQAIANRFT+N++GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISIAQTTEGALNEINNNLQRIRELTVQASSGTNSPSDLESIQNEITQRLG 121 TQA+RNANDGISIAQTTEGALNEINNNLQR+REL+VQA++GTNS SDL+SIQ+EI QRL Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EITRVSEQTQFNGVKVLANDQSLTIQVGANDNETITIDLKQVNATTLGLDKLDVGSQLTS 181 EI RVS QTQFNGVKVL+ D + IQVGAND ETITIDL++++ +LGLD +V + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 KNFANVTTIAASAPAEWTDFSFAVEGGSTFTLAVGTDNQLYATDGTDYYEATFNADTGTV 241 ++ + + AV TD Y A T Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDD 240 Query: 242 TVGAITAGIAASNINADATEFDTADGVVTLADAEAATLVEPAAPSVSTVYMDNTGTTTAY 301 + + + T A E T N G Sbjct: 241 AENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVS 300 Query: 302 YVKAGGTYYDAEIDLDTGEVSVNLGSATSTLAAGTAVTAQAVLTAAADPGVAVDLSTVNS 361 G D+ G +V+ + S+ T+V + LS + + Sbjct: 301 TTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEA 360 Query: 362 TFSGTNSLVRDSETGAYYVKNVSGDKTSYYEATVDLDTGVVTATADDEIVV-------DP 414 + Y T + T +T +E +P Sbjct: 361 NNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANP 420 Query: 415 LNAIDNALSAVDSLRSDLGAIQNRFESTITNLNNTVNNLSAARSRIEDADYATEVSNMTK 474 L +ID+ALS VD++RS LGAIQNRF+S ITNL NTV NL++ARSRIEDADYATEVSNM+K Sbjct: 421 LASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSK 480 Query: 475 AQILQQAGTSVLAQANQVPQTVLSLLR 501 AQILQQAGTSVLAQANQVPQ VLSLLR Sbjct: 481 AQILQQAGTSVLAQANQVPQNVLSLLR 507
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 37.1 bits (86), Expect = 7e-05 Identities = 17/44 (38%), Positives = 27/44 (61%) Query: 4 VIGYAVVLVAVIGSFAALGGHMGALYQPFELTLIAGGALGAFLA 47 ++G A+VL AV A GG GA+Y+ F +T+++ AL +A Sbjct: 442 LVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 49.2 bits (117), Expect = 8e-09 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 13/120 (10%) Query: 167 FATGSAEVQPYMRDILRELGPVLNEL---PNKISIAGHTDATQYARGERAYSNWELSADR 223 F A ++P + L +L L+ L + + G+TD G AY N LS R Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR----IGSDAY-NQGLSERR 277 Query: 224 ANASRQELVAGGMAEGKLMRIQGLSSSMSLVKDDPYAAVNRR---ISLVVLNRRTQQQIE 280 A + L++ G+ K + +G+ S + V + V +R I + +RR + +++ Sbjct: 278 AQSVVDYLISKGIPADK-ISARGMGES-NPVTGNTCDNVKQRAALIDCLAPDRRVEIEVK 335
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 8e-21 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 2/121 (1%) Query: 3 ATILVADDSATMRMIVQATLTEAGWRVLTAGNGQQALELARGNRVDMLVSDWNMPVMGGL 62 ATILVADD A +R ++ L+ AG+ V N D++V+D MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 ALIQGLRGEPGYQDLPVLVLTTEDDVQSKDAARGLGVCGWLNKPLDPGVLVELASELLGE 122 L+ ++ DLPVLV++ ++ + A G +L KP D L+ + L E Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 Q 123 Sbjct: 122 P 122
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 1e-05 Identities = 13/78 (16%), Positives = 33/78 (42%), Gaps = 10/78 (12%) Query: 408 ELDKSLIERIIDPLT--HLVRNSLDHGIETPEKRIAAGKDPVGQLILSAEHNGGNIVIEV 465 +++ ++++ + P+ LV N + HGI G+++L + G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 466 SDDGAGLNRDKILKKAIA 483 + G+ ++ Sbjct: 297 ENTGSLALKNTKESTGTG 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 1e-14 Identities = 44/191 (23%), Positives = 81/191 (42%), Gaps = 26/191 (13%) Query: 2 MKKIRVLCVDDSALVRGLMTEIINSHDDMEVVAVAPDPLVARELIKQHNPDVLTLDVEMP 61 M +L DD A +R ++ + ++ +V + + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSR-AGYDVRITS-NAATLWRWIAAGDGDLVVTDVVMP 58 Query: 62 RMDGLDFLEKLMRLRP-MPVVMVSSLTERGGETTLRALELGAIDFVTKPKLGIRHGMLEY 120 + D L ++ + RP +PV+++S+ T ++A E GA D++ KP + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNT--FMTAIKASEKGAYDYLPKP--------FDL 108 Query: 121 SELIADKIRAAARARLRVPAASAQAAPPARLRSPFASSEKLVIVGASTGGTEAIREVLRP 180 +ELI RA A + R + + + +VG S E R + R Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDS------------QDGMPLVGRSAAMQEIYRVLARL 156 Query: 181 LPPDSPAVLIT 191 + D ++IT Sbjct: 157 MQTDLT-LMIT 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 1e-22 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 3/105 (2%) Query: 7 KILVVDDFPTMRRIIRNLLKELGFENVDEAEDGAIGLEKLRNGSFQFVVSDWNMPNLDGL 66 ILV DD +R ++ L G++ V + A + G VV+D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 EMLKQIRADGALKSLPVLMVTAEAKKENIVAAAQAGANGYVVKPF 111 ++L +I+ A LPVL+++A+ + A++ GA Y+ KPF Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.020 Identities = 28/126 (22%), Positives = 40/126 (31%), Gaps = 18/126 (14%) Query: 49 ARPLHRFLARMRGHVVAVRQASIQIALNAAR---TQYQASQCASLAREQAAAAEALAGSG 105 A LH +LA R + R T Q A L RE A AAE A G Sbjct: 731 AEALHLYLAGERYFPSPEDEEIYFRPEQELRLVETGVQGRLWALLTREGAPAAEGAAQKG 790 Query: 106 SQIEQLSDAASAHMREIAQ-VSARNLEAARAALLALGDVMGRME-------RMTAEMAGL 157 + + IA V A + +++ + G V + R T+ Sbjct: 791 Y-------SVNTTFVTIADLVQALGADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRRR 843 Query: 158 AGVVEQ 163 + Q Sbjct: 844 GYMRPQ 849
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 357 bits (919), Expect = e-125 Identities = 98/343 (28%), Positives = 174/343 (50%), Gaps = 3/343 (0%) Query: 8 EKTEAASPRRLEKAREEGQIARSRELGTFLLLAAGVGGLWLSGSMLYRGLTGVLRNGLGF 67 EKTE +P+++ AR++GQ+A+S+E+ + L+ A L + + ++ + Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML--IPA 61 Query: 68 DARIGRDPGIMVAQAVDGAGQALLLVLPIFGVLMAVAVLASVVLGGFVFSAKPLQPDFAK 127 + + + + L P+ V +A+ + VV GF+ S + ++PD K Sbjct: 62 EQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 128 LSLFSGLKRMVSAQTVVELLKAVAKALLVGGVAVAVIGGHRDEMLALMHAAPTEALVKAL 187 ++ G KR+ S +++VE LK++ K +L+ + +I G+ +L L Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 188 TLVALCAALIVASLGIIVLLDVPWQIWSHLKKLRMSKEDVRQEHKESEGDPHIKARIRQQ 247 ++ + +I + D ++ + ++K+L+MSK+++++E+KE EG P IK++ RQ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 248 QRSMARRRMMSEVPRADVVVTNPTHYAVALRYAEGQA-APRVVAKGTGLVAARIRELAAG 306 + + R M V R+ VVV NPTH A+ + Y G+ P V K T +R++A Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEE 301 Query: 307 HRVPLLQAPPLARALYQHVELGQEIPAALYTAVAEVLAWVFQL 349 VP+LQ PLARALY + IPA A AEVL W+ + Sbjct: 302 EGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 5e-06 Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 9/119 (7%) Query: 296 SGEYSGLSINSDGTLQANYTNGETAIIGTLALAN-FNNVQGLQPVGNNAWAETGASGQPT 354 S E +G S N +G + + + G + + + ++ +GN + T Sbjct: 436 SEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSD--IGNKT------ATLKT 487 Query: 355 LGQPGTNGLATVVGQAVEASNVDMSKELVNMIVAQRTYQANAQTIKTQDEVMQVLMNMR 413 N + + Q S V++ +E N+ Q+ Y ANAQ ++T + + L+N+R Sbjct: 488 SSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 38.0 bits (88), Expect = 6e-05 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 4/56 (7%) Query: 6 GLSGLNAAAQNLDVIGNNIANSGTVGFKSATASFAD----VYASSRVGLGVKVSAI 57 +SGLNAA L+ NNI++ G+ T A + A VG GV VS + Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.0 bits (101), Expect = 6e-07 Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 14/80 (17%) Query: 4 SLWIAKTGLEGQQTSMDVISNNLANVQTNGFKRGRAIFQDLMYQTLRQPGAQVGDANQLP 63 + A +GL Q +++ SNN+++ G+ R I + L Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTLG 48 Query: 64 TGLQLGTGVRVASTERVFTQ 83 G +G GV V+ +R + Sbjct: 49 AGGWVGNGVYVSGVQREYDA 68 Score = 43.0 bits (101), Expect = 7e-07 Identities = 12/48 (25%), Positives = 24/48 (50%) Query: 214 SILQQYVETSNVNVAEELVNMITTQRAYEMNSKAVKTSDEMLARLTQL 261 + Q S VN+ EE N+ Q+ Y N++ ++T++ + L + Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 206 bits (525), Expect = 3e-69 Identities = 120/222 (54%), Positives = 155/222 (69%), Gaps = 6/222 (2%) Query: 9 AAVLALAAAGCAMIPPEPVVTGPVTAAPPPPPMPAAQPNGSIY---QPRVYGNYPLFEDR 65 +++L L+ GCA IP P+V G +A P P P P A NGSI+ QP YG PLFEDR Sbjct: 12 SSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVA--NGSIFQSAQPINYGYQPLFEDR 69 Query: 66 RPRNVGDIVTIVLNERTNAAKNVATNTDRSGNVGLGIAATPGFMDSW-ANAKLNTDASGS 124 RPRN+GD +TIVL E +A+K+ + N R G G P ++ NA+ + +ASG Sbjct: 70 RPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGG 129 Query: 125 NKASGKGDSSANNTFTGTITTTVIGVLPNGNLQVAGEKQIAINRGSEYVRFSGVVDPRSI 184 N +GKG ++A+NTF+GT+T TV VL NGNL V GEKQIAIN+G+E++RFSGVV+PR+I Sbjct: 130 NTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTI 189 Query: 185 TGANSVSSTQVADARIEYRSKGVMDEVQTMGWLQRFFLIASP 226 +G+N+V STQVADARIEY G ++E Q MGWLQRFFL SP Sbjct: 190 SGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSP 231
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 380 bits (977), Expect = e-133 Identities = 160/368 (43%), Positives = 219/368 (59%), Gaps = 11/368 (2%) Query: 13 LAGCVLAAALLMLAGPAQAE--RIKDLASIQGVRGNPLIGYGLVVGLDGSGDQVRQTPFT 70 A V +A + PAQA+ RIKD+AS+Q R N LIGYGLVVGL G+GD +R +PFT Sbjct: 8 AAALVFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFT 67 Query: 71 QQSLTNMLSQLGITVPPGSNMQLKNVAAVMVTATLPAFARPGQRLDVVVSSMGNAKSLRG 130 +QS+ ML LGIT G + KN+AAVMVTA LP FA PG R+DV VSS+G+A SLRG Sbjct: 68 EQSMRAMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRG 126 Query: 131 GTLLMTPLKGADSQVYAIAQGNILVGGAGASAGGSSVQINQLNGGRINDGAIVERGVPTS 190 G L+MT L GAD Q+YA+AQG ++V G A +++ R+ +GAI+ER +P+ Sbjct: 127 GNLIMTSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSK 186 Query: 191 FSRDGLIYLEMDVTDFGTTQNVVAALNR----QFGAGTAEAVDGRVVQVRGPLDAAEQAA 246 F + L++ DF T V +N ++G AE D + + V+ P A+ Sbjct: 187 FKDSVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTR 245 Query: 247 FLARVENLQVRRAPATAKVIINARTGSVVMNQTVMIDEAAVAHGNLSVIINRQTQVSQPD 306 +A +ENL V AKV+IN RTG++V+ V I AV++G L+V + QV QP Sbjct: 246 LMAEIENLTV-ETDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP- 303 Query: 307 TPFGGGQTVVVPNTQIEVRQEDGALHRVRTSANLADVVKALNALGATPQDLLAILQAMKS 366 PF GQT V P T I QE + + +L +V LN++G ++AILQ +KS Sbjct: 304 APFSRGQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKS 362 Query: 367 AGALRADL 374 AGAL+A+L Sbjct: 363 AGALQAEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 209 bits (532), Expect = 5e-68 Identities = 115/279 (41%), Positives = 168/279 (60%), Gaps = 9/279 (3%) Query: 29 VRAKPGDSAAQ--KQVATQVEALFLQMMLKRMREAGPKSGLFDSQQSQMMQSMADEQLAL 86 ++AK G+ A + VA QVE +F+QMMLK MR+A PK GLF S+ +++ SM D+Q+A Sbjct: 21 LKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQ 80 Query: 87 QL-ARPGVGLAQAMLRQMQQGRPAGVADAALDGV--LQNDSAPRRVTALLDVLRNNRASD 143 Q+ A G+GLA+ M++QM +P + + AL +++ + Sbjct: 81 QMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRN 140 Query: 144 RALAAAEGAPVHVVDFVSRMAGPAQEAARQTGVPARLILGQAALESGWGRRELKYDNGAT 203 + P F+++++ PAQ A++Q+GVP LIL QAALESGWG+R+++ +NG Sbjct: 141 ----YDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEP 196 Query: 204 SYNLFGIKAGSSWNGKVVNVLTTEYEDGVARKVVQPFRAYGSYEESFADYARLIGENPRY 263 SYNLFG+KA +W G V + TTEYE+G A+KV FR Y SY E+ +DY L+ NPRY Sbjct: 197 SYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRY 256 Query: 264 EPVLQARDEIDAARRIQAAGYATDPAYADKLIAIMGQLR 302 V A A+ +Q AGYATDP YA KL ++ Q++ Sbjct: 257 AAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMK 295
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 355 bits (911), Expect = e-118 Identities = 221/551 (40%), Positives = 338/551 (61%), Gaps = 9/551 (1%) Query: 2 NLYNLALTGLNASQAGMEVTSHNINNAANAGYSRQRLVTSTAGATETGQGFFGRGVQVDT 61 +L N A++GLNA+QA + S+NI++ AGY+RQ + + A +T G+ G GV V Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 62 VKRQYDSFLYRQMVGAQGTGAQLATHYDQVSQINNLFGDRTVGITPALENFFASLNAGAS 121 V+R+YD+F+ Q+ AQ + L Y+Q+S+I+N+ T + +++FF SL S Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 122 NPADPAVRQDILGKTNSLVTQINTAYRELQNLREGVNTQISTTVEQVNSYLERINDLNKQ 181 N DPA RQ ++GK+ LV Q T + L++ + VN I +V+Q+N+Y ++I LN Q Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 182 IVVAQG-KSGHAPNDLLDQRDQALSELNQLVGVRYY-EQGNSLNITLQSGQTLLSGTTVY 239 I G +G +PN+LLDQRDQ +SELNQ+VGV + G + NIT+ +G +L+ G+T Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 240 PLAAVQSASDPTRMALAYSLPAGSGSTVQVELSDSEISGGKLAGFLQFRSQSLDAVQDQL 299 LAAV S++DP+R +AY G+ +E+ + ++ G L G L FRSQ LD ++ L Sbjct: 242 QLAAVPSSADPSRTTVAYV----DGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTL 297 Query: 300 GQLAIGLALAFNAQHEAGLDLNGDPGEALFGLSQPAAIPKVGNTGDGSLTAEFTDASAIH 359 GQLA+ A AFN QH+AG D NGD GE F + +PA + N GD ++ A TDASA+ Sbjct: 298 GQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVL 357 Query: 360 ATSYDIVYNGTQYVVTRQSDGAVQTLTPSADTPPTIEFDGMTVTVDGTPAAGDVWKLQAT 419 AT Y I ++ Q+ VTR + T+TP A+ + FDG+ +T GTPA D + L+ Sbjct: 358 ATDYKISFDNNQWQVTRLASNTTFTVTPDANG--KVAFDGLELTFTGTPAVNDSFTLKPV 415 Query: 420 RDAARDLKALITDPAKLALA-DAAGGTTNGANGLLLAKLQTEKVLGGGTLSLSGQFSQLI 478 DA ++ LITD AK+A+A + G ++ NG L LQ+ GG S + ++ L+ Sbjct: 416 SDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLV 475 Query: 479 NNIGVQTQQIKTAATAQDNLITQQTSAYLSVSGVNLNEEYVNLTIYQEQYQASAKILDVA 538 ++IG +T +KT++ Q N++TQ ++ S+SGVNL+EEY NL +Q+ Y A+A++L A Sbjct: 476 SDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTA 535 Query: 539 STVFDTLLGLR 549 + +FD L+ +R Sbjct: 536 NAIFDALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.8 bits (108), Expect = 2e-07 Identities = 49/239 (20%), Positives = 88/239 (36%), Gaps = 9/239 (3%) Query: 1 MRLSTALIYQNGLNGILKQESTLSRLQEQLASGRRVLTPADDPLAASLAVNVSQTSSMNA 60 ++T + N + K +S+LS E+L+SG R+ + DD AA A+ TS++ Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDD--AAGQAIANRFTSNIKG 59 Query: 61 TYASNRNT--AKQTLGLESNALSSVVTTLQSVLQRVVQAG-GTLSDPDRQALVTELEASR 117 ++RN AL+ + LQ V + VQA GT SD D +++ E++ Sbjct: 60 LTQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRL 119 Query: 118 DQLVGLANSTDGNGQYLFSGHQGFSAPVTLDADGNVSYGGDN----GQRLIQVDQSRQMA 173 +++ ++N T NG + S V + ++ L + + Sbjct: 120 EEIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 174 GSDVISDIFGKASAGSKAYIVEANEANTGTGQFSSVSFDTTTGSGANQDFIVTFSDVGG 232 + K G Y V AN+ + V+ T + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.9 bits (72), Expect = 0.006 Identities = 12/128 (9%), Positives = 26/128 (20%), Gaps = 8/128 (6%) Query: 520 IEVPAQQLTAQHAPRVAESARQSAATATTAARGAEPAPSAPLRQLPGATTQAPAPAAAAA 579 + + A ++ + EP P P P P Sbjct: 52 VTMVAPADLEP-----PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 106 Query: 580 APR-TARSVRRADQASAPAESTASSVTRRAAAAQPQAEG--ASASRPARRPTVAATGPIA 636 + + R + S + + + A P + Sbjct: 107 PVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Query: 637 ANSAARRA 644 + A+ Sbjct: 167 YPARAQAL 174
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 324 bits (833), Expect = e-110 Identities = 117/343 (34%), Positives = 174/343 (50%), Gaps = 31/343 (9%) Query: 52 GMCPLMREFGSQVARAARSDATVFITGESGTGKEMIARAIHEGSERSKHPFIPVNCGAFS 111 G M+E +AR ++D T+ ITGESGTGKE++ARA+H+ +R PF+ +N A Sbjct: 141 GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIP 200 Query: 112 HSLAHAQLFGHEKGSFTGALGQTAGYFESAGNGTLFLDEVTEMSDALQVQFLRVLESGTY 171 L ++LFGHEKG+FTGA ++ G FE A GTLFLDE+ +M Q + LRVL+ G Y Sbjct: 201 RDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEY 260 Query: 172 QRVGGTEVLHTGARIVCATNRDPYAAVESGKLRQDFLHRLLIVPLRVPPLREREGDVRIL 231 VGG + + RIV ATN+D ++ G R+D +RL +VPLR+PPLR+R D+ L Sbjct: 261 TTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDL 320 Query: 232 AQRFLDELNAAHKTSKRFSARMMDALLSYDWPGNVRELRNAVQRAFIMAD---------- 281 + F+ + KRF ++ + ++ WPGNVREL N V+R + Sbjct: 321 VRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIE 380 Query: 282 TVVEAEFRRRPRAAEARDSTDGALCFPVGTPLSQA---------------------QRDV 320 + +E P A S ++ V + Q + + Sbjct: 381 NELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPL 440 Query: 321 ILATLAHHNGDKQRTADTLGVSLKTLYNRLGAYNADTPTSTRQ 363 ILA L G++ + AD LG++ TL ++ S+R Sbjct: 441 ILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSSRS 483
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 464 bits (1195), Expect = e-163 Identities = 167/471 (35%), Positives = 252/471 (53%), Gaps = 34/471 (7%) Query: 2 PHMLVLDDDEAVREVLAEIAREHGFSVAQAATMKDAMIQLQRQQPDLVLTDVRLPGASGM 61 +LV DDD A+R VL + G+ V + + DLV+TDV +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EIFGRMQ--NSDAEVVVITGHGTMDNAVEALRLGATDYLVKPVCMDRLAEILTRVAADRG 119 ++ R++ D V+V++ T A++A GA DYL KP + L I+ R A+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 120 GAANDGPFQEPGRFGKLLGQSESMEQLYAQLSRVAATDATTLLIGESGTGKELAAHAIHE 179 + + L+G+S +M+++Y L+R+ TD T ++ GESGTGKEL A A+H+ Sbjct: 124 RRPSKLE-DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 180 LSSRASKPFIAVNCGAISPHLIESELFGHERGSFTGADRQHKGYFERADSGTLFLDEVTE 239 R + PF+A+N AI LIESELFGHE+G+FTGA + G FE+A+ GTLFLDE+ + Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGD 242 Query: 240 MPLDLQVKLLRVLETGRFMRVGTHREVACDVRIVAATNRSPEQAIQEGKLREDLYYRLSV 299 MP+D Q +LLRVL+ G + VG + DVRIVAATN+ +Q+I +G REDLYYRL+V Sbjct: 243 MPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNV 302 Query: 300 FPIELPPLRERGTDILFLADRFLQALNDKYGESRRFSEQARQAIGEYAWPGNVRELKNYV 359 P+ LPPLR+R DI L F+Q + + +RF ++A + + + WPGNVREL+N V Sbjct: 303 VPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 360 RRAYIMAEDGILGADALQPQIAPD-------------------------------GGGQA 388 RR + ++ + ++ ++ + G A Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 389 ARVVVPLGVTLAEADRRLIMATLERCGGVKKQTAAVLGISAKTLYNRLEEY 439 LAE + LI+A L G + + A +LG++ TL ++ E Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.8 bits (61), Expect = 0.005 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 5/58 (8%) Query: 8 DAAPGRAQTYPPKEPVQDPPVRPDDTPEDTPRKPYPPDSIPNPM--PGLDPQQTPGID 63 D PG A+ P +P+ P V P + P + P P + PNP P L+P P D Sbjct: 314 DLTPGSAEA-PNAQPL--PEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTD 368
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 5e-11 Identities = 20/95 (21%), Positives = 38/95 (40%) Query: 24 DRIRETARRMFYQDGIRAVGVDALVAEAGVTKPSLYRSFSSKDELAASYLRDYEAEFWSK 83 I + A R+F Q G+ + + + AGVT+ ++Y F K +L + E+ Sbjct: 14 QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGEL 73 Query: 84 FEAGWQQHPDDPRAALMVYFGSLAQRAASSDGYRG 118 + P DP + L + + + + R Sbjct: 74 ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL 108
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.4 bits (84), Expect = 2e-04 Identities = 26/134 (19%), Positives = 46/134 (34%), Gaps = 7/134 (5%) Query: 24 VIFLALLVSAGLRSTP---SVLLVPLEESFGWSRATTSFSAAI---GIFLYGLVGPFAAA 77 + F+ ++ G+ V +VP +T + I G + G Sbjct: 256 IPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI 315 Query: 78 AMERFGLRRVLIGALALMAASTFASSFMTEPWHLLLTWGV-FSGIGSGAVAVVLGATVVN 136 ++R G VL + ++ S +SF+ E +T + F G V+ V + Sbjct: 316 LVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSS 375 Query: 137 RWFATRRGLMMGLL 150 G M LL Sbjct: 376 SLKQQEAGAGMSLL 389
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.030 Identities = 11/21 (52%), Positives = 12/21 (57%) Query: 35 LIGPNGAGKTTLFNVLTGLYI 55 L G G GK+TL N L GL Sbjct: 601 LEGTGGIGKSTLINTLVGLDF 621
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 22/102 (21%), Positives = 40/102 (39%), Gaps = 22/102 (21%) Query: 277 LIDNALRYG----QGGGRITLTVGLNPPSLT--VEDDGPGIPADEHERVFEAFYRSPGSM 330 L++N +++G GG+I L + ++T VE+ G + E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 331 AGGSGLGLAIVRE-IAHAHGAWWKLSSRPEYPGTRLSVVFPG 371 +G GL VRE + +G ++ + V+ PG Sbjct: 310 --STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.1 bits (247), Expect = 3e-26 Identities = 38/162 (23%), Positives = 76/162 (46%), Gaps = 7/162 (4%) Query: 2 RVLVIEDDTTLGHALQEFLADQGYAVDWLTDGDKVLGALAGQSYDLLLLDLNLPGRSGLD 61 +LV +DD + L + L+ GY V ++ + +A DL++ D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRQLRQDGNQVPVLIVTARDGLEDRVAGLDAGADDYVTKPFDLPELAARVRAFGRRRAG 121 +L ++++ +PVL+++A++ + + GA DY+ KPFDL EL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 QAQPLIEAGTLTFDTVG-----REVRANGQRLSLSVRELSVL 158 + L + VG +E+ RL + +L+++ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT--DLTLM 164
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 96.2 bits (239), Expect = 4e-26 Identities = 56/165 (33%), Positives = 78/165 (47%), Gaps = 3/165 (1%) Query: 84 EPEPEPEPEPEPVVEPEPEPVIEPEPEPEPPVIEKAPEPAPKPKPKPKPKPKPKPKPKIE 143 EP +P PEPVVEPEPEP PEP E PV+ + P+P PKPKPKP K + +PK ++ Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVK 115 Query: 144 KPVEPPKPVQPPSGAPEGAEVTQAPVQGPPPNEPIMVSSVEYLGRRPMPVYPMTSKRLRE 203 P P A +T + V+S R P YP ++ LR Sbjct: 116 PVESRP---ASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRI 172 Query: 204 EGRVVVLVEINTQGLVERASIAQSSGYNRLDDSALAAARKARFKP 248 EG+V V ++ G V+ I + N + A R+ R++P Sbjct: 173 EGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEP 217
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 1e-25 Identities = 32/123 (26%), Positives = 63/123 (51%) Query: 8 LLIDDDELYVRTLQRSLARHGLETRVATSIAEALRVAEDMLPSFALVDLRLGEDSGLTLI 67 L+ DDD L ++L+R G + R+ ++ A R + D+ + +++ L+ Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66 Query: 68 RPLRALRADMRILLVTGYASVATAVEAIKRGADDYLPKPATAPMILRTLGLAKAESVAIE 127 ++ R D+ +L+++ + TA++A ++GA DYLPKP ++ +G A AE Sbjct: 67 PRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRP 126 Query: 128 STM 130 S + Sbjct: 127 SKL 129 Score = 50.6 bits (121), Expect = 7e-10 Identities = 15/40 (37%), Positives = 24/40 (60%) Query: 133 LHRLEWEHIQQALHECGGNVSAAARLLGMHRRSLQRKLAK 172 L +E+ I AL GN AA LLG++R +L++K+ + Sbjct: 433 LAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>PF03627#PapG Length = 336 Score = 29.9 bits (67), Expect = 0.019 Identities = 15/47 (31%), Positives = 19/47 (40%), Gaps = 2/47 (4%) Query: 87 HWPGGLATATLMSCGMFSTINGSSVATAATIGTVAIPE--MTQRGYN 131 W G+AT T C +GS I V P+ MT+ GY Sbjct: 51 SWRPGIATVTWNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYP 97
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.007 Identities = 24/156 (15%), Positives = 55/156 (35%), Gaps = 14/156 (8%) Query: 128 SETEALRRAIVAQFEQYVKLNKKIPPEILTSLAGIDDAGRLADTIAAHLPLKLEQKQKML 187 ++ E + K + E A + + + + + Sbjct: 228 ADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT-- 285 Query: 188 EILGTSERLEGLLTQLETEIDILQVEKRIRGRVKKQMEKSQRDYYLNEQVKAIQKELGEG 247 + LE LE + +L R +++ ++ S+ K ++ E + Sbjct: 286 -LEAEKAALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK------KQLEAEHQKL 335 Query: 248 EEGADIEELEKKIIAAHM--PKEARKKADAELKKLK 281 EE I E ++ + + +EA+K+ +AE +KL+ Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLE 371
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.042 Identities = 12/46 (26%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 109 VELSKSNIMLIGPTGSGKTLLAQTL---ARMLNVPFVMADATTLTE 151 + + +M+ G +G+GK L+A+ L + N PFV + + Sbjct: 156 LMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPR 201
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 28.7 bits (64), Expect = 0.020 Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 44 AEIKTLSDQACAAS-DKQEKVAKSGSKYDARLQKLAKALGTKVNGQPASYKVYITS 98 K ++ Q A + +E K+ +Y +L KL K K N PA K+ +TS Sbjct: 149 IFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTS 204
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 4e-04 Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 6/97 (6%) Query: 39 TVESDKASMEIPASSGGVVKSVKVKVGDKVAEGKVILQVEAGETK------EAKPAPAAS 92 + S EI +VK + VK G+ V +G V+L++ A + ++ A Sbjct: 89 KLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148 Query: 93 QVSDSQRVSDTVTKEKAPQKGQPVNAAAQYSGSADVE 129 + + Q +S ++ K P+ P Q +V Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.3 bits (84), Expect = 3e-04 Identities = 23/106 (21%), Positives = 41/106 (38%), Gaps = 8/106 (7%) Query: 168 TVESDKASMEIPASAGGVVKEVKVKVGDKVAKGTAIAVVEGQGGAQAEPQKAQAP---AQ 224 + S EI +VKE+ VK G+ V KG + + GA+A+ K Q+ A+ Sbjct: 89 KLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLT-ALGAEADTLKTQSSLLQAR 147 Query: 225 AQEQQPSGAASASAAAPAPA----AKPAPAAALEDPGLKPGQLPHA 266 ++ + + + P +P E+ L+ L Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Score = 33.6 bits (77), Expect = 0.002 Identities = 19/94 (20%), Positives = 35/94 (37%), Gaps = 3/94 (3%) Query: 39 TVESDKASMEIPASSGGVVKSVKVKVGDKVAEGKVILEVEAGEA---AGADQAPASPDKA 95 + S EI +VK + VK G+ V +G V+L++ A A Q+ + Sbjct: 89 KLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148 Query: 96 DAAAKQPSSGDAPKTQGQTVEAPDVKPAADAGKG 129 + Q S + ++ PD + + Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 121 bits (304), Expect = 2e-34 Identities = 39/152 (25%), Positives = 70/152 (46%) Query: 6 QSSTVFIVDDDEAVRDSLRWLLEANGYRVRAFASGETFLEEYDPSQVGVLIADVRMPGMS 65 +T+ + DDD A+R L L GY VR ++ T +++ DV MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GLELQEQILARNAPLPIVFITGHGDVPMAVSTMKKGAVDFLEKPFNESDLREIVARMLEQ 125 +L +I LP++ ++ A+ +KGA D+L KPF+ ++L I+ R L + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 126 ATQRVSQFQAQKDHEAMLARLTAREQQVLERI 157 +R S+ + L +A Q++ + Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 29.7 bits (66), Expect = 0.003 Identities = 11/49 (22%), Positives = 15/49 (30%), Gaps = 2/49 (4%) Query: 83 ARFIRETYRAFEDI--LGELHPCCYVHVIDARAAAYGYGGATQEYRHQH 129 F E I L EL + H + R G G + Y+ Sbjct: 480 GTFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGV 528
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 163 bits (414), Expect = 4e-45 Identities = 95/435 (21%), Positives = 166/435 (38%), Gaps = 62/435 (14%) Query: 5 LRNVAIIAHVDHGKTTLVDQLLRQSGTFRENQAVSE--RVMDSNDLEKERGITILAKNCA 62 + N+ ++AHVD GKTTL + LL SG E +V + D+ LE++RGITI + Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 63 VEYQGTHINIVDTPGHADFGGEVERVLSMVDGVLLLVDAVEGPMPQTIFVTRKALALGLK 122 +++ T +NI+DTPGH DF EV R LS++DG +LL+ A +G QT + +G+ Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 123 PIVVVNKIDRPGAR-------------PDYVINATFDLFDKLGATEEQL----------- 158 I +NKID+ G + VI +L+ + T Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182 Query: 159 -DFPVVYASG--LSG---YAGLTAEVREGDMRPLF--------------EAILQHVPQRE 198 D Y SG L + + P++ E I Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSST 242 Query: 199 DDPNGPLQMQIISLDYNSYVGKIGVGRINRGRIRPGMDVVYQFGPEGASGKGRINQVLKF 258 L ++ ++Y+ ++ R+ G + D V E K +I ++ Sbjct: 243 HRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLR-DSVRISEKE----KIKITEMYTS 297 Query: 259 KGLEREVVSEAEAGDIVLINGIEEIGIGCTVMDPAQPEAFPMLRIDEPTLTMNFMVNTSP 318 E + +A +G+IV++ E + + + D + P L + Sbjct: 298 INGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQ 356 Query: 319 LAGREGKFVTSRQLRDRLDRELKSNVALRVRDTGDDTVFEVSGRGELHLTILLETMRRE- 377 L D L S+ LR +S G++ + + ++ + Sbjct: 357 QREM---------LLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKY 407 Query: 378 GYELAVSRPRVVFKD 392 E+ + P V++ + Sbjct: 408 HVEIEIKEPTVIYME 422 Score = 31.4 bits (71), Expect = 0.014 Identities = 16/88 (18%), Positives = 29/88 (32%), Gaps = 2/88 (2%) Query: 399 EPFEALTIDVEDAHQGGVMEELGRRKGDLQDMQPDGRGRTRLEYLIPARGLIGFQNEFLT 458 EP+ + I + + + ++ D Q L IPAR + ++++ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQL-KNNEVILSGEIPARCIQEYRSDLTF 595 Query: 459 LTRGTGLMSHIFHEYAP-VREGSIGERR 485 T G + Y E RR Sbjct: 596 FTNGRSVCLTELKGYHVTTGEPVCQPRR 623
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 83.4 bits (206), Expect = 2e-18 Identities = 68/277 (24%), Positives = 98/277 (35%), Gaps = 76/277 (27%) Query: 499 VMGHVDHGKTSLLDYI-----RRAKVASGEAG-------------GITQHIGAYHVETAR 540 V+ HVD GKT+L + + ++ S + G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 541 GVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTREAIHHAKAGGVPLVVAV 600 V +DTPGH F A R D IL+++A DGV QTR H + G+P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 601 NKIDKPEANPERVKQ--------------------------------------------- 615 NKID+ + V Q Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 616 ------ELVAEEVVPEEYGG--DVPFVPV---SAKTGAGIDDLLENVLLQAEILELTAPV 664 L A E+ EE + PV SAK GID+L+E + + T Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 665 EAPAKGLVIEARLDKGRGPVATILVQSGTLKRGDVVL 701 ++ G V + + R +A I + SG L D V Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVR 282
>cloacin#Cloacin signature. Length = 551 Score = 30.5 bits (68), Expect = 0.024 Identities = 26/101 (25%), Positives = 33/101 (32%) Query: 404 GRRGKLQGGGPGSAGHVASSPSDPFGTGLMFAGGYANGHPLGKDAGRGKGGGKPGGKSGG 463 G L GG S G SS ++P+G G + G G G G GG G Sbjct: 22 GGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Query: 464 KPGGFKAAGAKAGGAKPGGAKPAKNAKARRPKPGVAGGAAA 504 A + PG A + A +A AA Sbjct: 82 SAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAA 122
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 4e-05 Identities = 30/148 (20%), Positives = 41/148 (27%), Gaps = 15/148 (10%) Query: 201 AAAEAGVSVEANAAAETEAAEEAAIQEAVVEEAVAAPDAAAVEGVAAEADAVAVAEDPAP 260 A EA +V+AN A + +E E E E + E P Sbjct: 1068 VAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ--EVPKV 1125 Query: 261 VAQTGDLPAEPDMPPPAPDHIPQPGAQPEVEPVAPEPEITPADP---QPEIEPPTPE--P 315 +Q P QP A+P E P + E P E Sbjct: 1126 TSQVS--------PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Query: 316 EVEPRLPDPDVEPPAPEVPPTPDEDQPA 343 VE + + V P+ PA Sbjct: 1178 NVEQPVTESTTVNTGNSVVENPENTTPA 1205 Score = 37.0 bits (85), Expect = 1e-04 Identities = 27/163 (16%), Positives = 42/163 (25%), Gaps = 14/163 (8%) Query: 202 AAEAGVSVEANAAAETEAAEEAAIQEAVVEEAVAAPDAAAVEGVAAE-------ADAVAV 254 E S +T +E A E + V V V ++ ++ V Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP 1141 Query: 255 AEDPAPVAQTGDLPAEPDMPPPAPDHIPQPGAQPEVEPVAPEPEITPADPQPEI------ 308 +PA EP QP + P E T + + Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 309 -EPPTPEPEVEPRLPDPDVEPPAPEVPPTPDEDQPAKGGLSQA 350 P T +P V + V P +PA + Sbjct: 1202 TTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 94.1 bits (234), Expect = 7e-24 Identities = 91/372 (24%), Positives = 142/372 (38%), Gaps = 44/372 (11%) Query: 1 MKKTLLAAALLAGFAGAAQAETSVTLYGVIDTGIGYNK-IKGDGYDGSRIGMINGI-QAG 58 MKK+L+A LA AA A VTLYG I G+ ++ + +G + + GI G Sbjct: 1 MKKSLIAL-TLAALPVAAMA--DVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLG 57 Query: 59 SRWGLRGSEDLGDGLRAVFQLESGFDSGNGNRAQGGRLFGRQATIGLANDSWGILEFGRQ 118 S+ G +G EDLG+GL+A++Q+E + G R Q+ IGL +G L GR Sbjct: 58 SKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGNR----QSFIGLKGG-FGKLRVGRL 112 Query: 119 TNMASKYLADIDPFYTSYTQANLGLGASSANTSRWDNMVMYRTPSVNGFELGVGYSFNVD 178 + K DI+P+ + LG A V Y +P G V Y+ N + Sbjct: 113 NS-VLKDTGDINPWDSKSDY--LG-VNKIAEPEARLISVRYDSPEFAGLSGSVQYALNDN 168 Query: 179 DGNADQTGFRTADNTRGITAGLRYLNGPLNITLTYDQLNGSNSSSQIDHDATPRQYAAGV 238 G N+ AG Y NG + ++ + + + Sbjct: 169 AGR---------HNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIE-KYQIHRLVS 218 Query: 239 SYDFEVVKLAAAYARTTDGWFTGQDLPSGTPYSNEFGSNRFVDGFKANAYMVGGTVP-IG 297 YD + + A+ + D + N + AY G P + Sbjct: 219 GYDNDAL-YASVAVQQQDA----------KLVEENYSHNSQTEVAATLAYRFGNVTPRVS 267 Query: 298 GASSVFASWQRVDPSNDRLTGGDSTMNVWSLGYTYDLSKRTNLYAYGSYGKDYAFIDGLK 357 A S+ ++ + +G YD SKRT+ + ++ Sbjct: 268 YAHGFKGSFDAT--------NYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFV 319 Query: 358 STAAGVGIRHQF 369 STA GVG+RH+F Sbjct: 320 STAGGVGLRHKF 331
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 49.5 bits (118), Expect = 1e-08 Identities = 77/418 (18%), Positives = 138/418 (33%), Gaps = 67/418 (16%) Query: 27 LDYMVFTFVISTLVTLWGIDRGQAGMLGTVTLLFSAIGGWGAGILADRYGRVRILQITIL 86 L+ MV + + + + T +L +IG G L+D+ G R+L I+ Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 87 WFSVCTVGIGFTQNFEQIFIL-RALQGLGFGGEWAVGSVLMGEIIKSQHRARAVGTVQSG 145 +V +F + I+ R +QG G A+ V++ I ++R +A G + S Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 146 WAVGWGVAALLYTIAFSVLPEQWAWRSLFWVGVLPALLVLYIRKHVPEPE---------- 195 A+G GV + + + W L + ++ + V ++ K + + Sbjct: 148 VAMGEGVGPAIGGM----IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKG 203 Query: 196 -----------------------------VFSHARKQPTADRPKVSPWLIFSPALLKTTL 226 + P V P L + + L Sbjct: 204 IILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL 263 Query: 227 LSALLCTGIQGGYYAVTTWLPTYLKVERHLSVLNTGGYLL--VIILGSFCGYIAGAHMAD 284 + I G + +P +K LS G ++ + GYI G + D Sbjct: 264 CGGI----IFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI-LVD 318 Query: 285 RLGRRINFVIYSVLSGVCVYVYTQVPLTDEQMLFLGFPLGFAASGIFGGLGAYLTELFPS 344 R G I V + + T + + + GGL T + Sbjct: 319 RRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVF------VLGGLSFTKTVISTI 372 Query: 345 EIRANGQGFAYNFGRGIGALFPSLVGYLSNSMGLAMAIGIFAGGAYTVVLIATLLLPE 402 + Q A G G+ L + +LS G+A+ GG ++ L+ LLP Sbjct: 373 VSSSLKQQEA---GAGMSLL--NFTSFLSEGTGIAI-----VGGLLSIPLLDQRLLPM 420 Score = 32.9 bits (75), Expect = 0.002 Identities = 28/155 (18%), Positives = 56/155 (36%), Gaps = 11/155 (7%) Query: 59 LFSAIGGWGAGILADRYGRVRILQITILWFSVCTVGIGFTQNFEQIFILRALQGLGFGGE 118 + I G+ GIL DR G + +L I + + SV + F F+ + + GG Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV-LGGL 362 Query: 119 WAVGSVLMGEIIKSQHRARAVG-------TVQSGWAVGWGVAALLYTIAF---SVLPEQW 168 +V+ + S + A T G + L +I +LP + Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEV 422 Query: 169 AWRSLFWVGVLPALLVLYIRKHVPEPEVFSHARKQ 203 + + +L + + + V+ H+++ Sbjct: 423 DQSTYLYSNLLLLFSGIIVISWLVTLNVYKHSQRD 457
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.2 bits (81), Expect = 4e-04 Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 4/177 (2%) Query: 57 IAVHNLVWGAAQPFAGAAADRYGSAPVVAFGAAAFAAGLALATAAQSPVLLVIGMGVLVG 116 +A++ L+ A P GA +DR+G PV+ A A A+ A +P L V+ +G +V Sbjct: 49 LALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAI--MATAPFLWVLYIGRIVA 106 Query: 117 IGISCTSFGVVLAAVGRAATPQRRSMALGLASAGGSVGQVALVPFAQVLRESAGVSASLL 176 GI+ + V A + R+ G SA G VA P L A Sbjct: 107 -GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVA-GPVLGGLMGGFSPHAPFF 164 Query: 177 GLAALMLLVAPLGMLLDRPAAQGGAPTAQEPALSLKQAVLHACRHRGYCLLTLGFFT 233 AAL L G L + +G + AL+ + A L FF Sbjct: 165 AAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFI 221
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 35.9 bits (83), Expect = 2e-04 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 6/111 (5%) Query: 22 LLDATSGQEMASFNADTRVEPASLTKVMTAYLVFQALRDGRLSTQQLVTVSTRAWKV-AP 80 +D SG+ + ++ AD R S KV+ V + G ++ + + +P Sbjct: 44 EMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP 103 Query: 81 GSSKMFLEPGKRVSVNDLLFGLLVQSGNDAAIVLAEAVSG--SVEAFVQRM 129 S K ++V +L + S N AA +L V G + AF++++ Sbjct: 104 VSEKHL---ADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQI 151
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 36.2 bits (84), Expect = 5e-06 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 8/97 (8%) Query: 46 NKSQLIAHLVEQTGVEAKSVKAVLAGLEGAVLGSVDKKGAGEFSLPGLFKVTVQKVPAKA 105 NK LIA + E T + K A + + AV + K + G F+V +A Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVR-----ERA 57 Query: 106 KRFGKDPFTGEERWFPAKPASVKVKVRPLKKLKDAAQ 142 R G++P TGEE AS + K LKDA + Sbjct: 58 ARKGRNPQTGEE---IKIKASKVPAFKAGKALKDAVK 91
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 0.001 Identities = 27/146 (18%), Positives = 49/146 (33%), Gaps = 6/146 (4%) Query: 38 PLLHTIGQQFGLSETAAGGIVTTAQLSYAAGLLLLVPLG----DMIERRALICAMTALAA 93 P+L + + S L YA P+ D RR ++ A AA Sbjct: 26 PVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGALSDRFGRRPVLLVSLAGAA 84 Query: 94 AGLLLSAFSTSAAMLLAGTAITGFLSVVAQVLVPFAATLASPQQRGKAVGTVMSGLLLGI 153 + A + +L G + G V + A + +R + G + + G+ Sbjct: 85 VDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGM 144 Query: 154 LLARTFAGMLAGLGSWRIVYWVAALL 179 + G++ G ++ AA L Sbjct: 145 VAGPVLGGLMGGFSP-HAPFFAAAAL 169
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 27.5 bits (61), Expect = 0.042 Identities = 14/58 (24%), Positives = 20/58 (34%), Gaps = 1/58 (1%) Query: 14 RWLLRAASLAAVMLLAACGFALRGVTPLPFDTLYVGIADNTRFGADIRRALRAASPNT 71 + A +A + A A+ +TPL YV D A I L + T Sbjct: 33 KLAWVVAGVAGALATAGV-VAVAALTPLKTVEPYVITVDRNTGEASIAAKLHGDATIT 89
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.002 Identities = 12/23 (52%), Positives = 16/23 (69%) Query: 38 VLVVVGPSGSGKSTLLRTLNGLE 60 +V+ G G GKSTL+ TL GL+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>PHPHLIPASEA1#Bacterial phospholipase A1 protein signature. Length = 289 Score = 89.6 bits (222), Expect = 3e-22 Identities = 57/223 (25%), Positives = 90/223 (40%), Gaps = 32/223 (14%) Query: 236 TTARFQISAKYRLFNPPGGRKPTFGENFYLGYTQTSLWDLESD--SMPFIDTTFNPSIF- 292 +FQ+S + L+ G YTQ S W L + S PF +T + P +F Sbjct: 85 DEVKFQLSLAFPLWRGILGPN----SVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFL 140 Query: 293 -WLSD---NLWTSSSQNWRLGLNTGIEHMSNGKSGDDSRSLNDAYIQPAINYRFDSGSTL 348 + +D WT + G H SNG+S SRS N Y + Sbjct: 141 GFATDYRFAGWTLRD------VEMGYNHDSNGRSDPTSRSWNRLYTRLMAEN-----GNW 189 Query: 349 TFAPKIRTYFAKESQNPDYADYAGYVDWNLRWAQDDGAVVSAMYRQGASR-HRTTQLDFA 407 K NPD Y GY + + D AV+SA + + + +L + Sbjct: 190 LVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGD-AVLSAKGQYNWNTGYGGAELGLS 248 Query: 408 WPLRRTWLDMNGYLHLQYFNGYGETLLGYNQRNESQFRIGLSL 450 +P+ + + L+ Q ++GYGE+L+ YN Q R+G+ + Sbjct: 249 YPITK-----HVRLYTQVYSGYGESLIDYNFN---QTRVGVGV 283
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 30.9 bits (70), Expect = 0.008 Identities = 16/83 (19%), Positives = 27/83 (32%), Gaps = 12/83 (14%) Query: 157 HSTGSIGVFGAAVAIGKLLGLEAAQMVWAIGLAATQSAGLR---EMFGSMAKSFHPGRSA 213 S ++ + + IG LG A+ ++AG +M S A P Sbjct: 66 FSFFALWLAVQQILIGIALGFTMQFAFAAV-----RTAGEIIGLQMGLSFATFVDPASHL 120 Query: 214 QSGYVAALLAQRG----FTAGGH 232 +A ++ T GH Sbjct: 121 NMPVLARIMDMLALLLFLTFNGH 143
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 34/157 (21%), Positives = 64/157 (40%), Gaps = 4/157 (2%) Query: 39 MAQDLGFSRSLLSGIVAIGMLCYGLGMPVAGMLVARRGTRFVLLLGTAI-VVGSIIWTVN 97 +A D + + + ML + +G V G L + G + +LL G I GS+I V Sbjct: 40 IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVG 99 Query: 98 ARGPVSFLLAFGVLMSVGLAFTSPVALTPVLTRWFTRRRGMALFFLSTGSMAGIAVMTPA 157 S L+ + G A + + V RG A + + +A + PA Sbjct: 100 -HSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGS-IVAMGEGVGPA 157 Query: 158 LTYAVESTTWQTTLLGFAVVFTVLTVPMAIFVMRDQA 194 + + + LL ++ T++TVP + +++ + Sbjct: 158 IGGMIAHYIHWSYLLLIPMI-TIITVPFLMKLLKKEV 193 Score = 28.7 bits (64), Expect = 0.049 Identities = 28/141 (19%), Positives = 52/141 (36%), Gaps = 8/141 (5%) Query: 20 LLTLLTVGMRM--GVGPFFLPMAQDLGFSRSLL-----SGIVAIGMLCYGLGMPVAGMLV 72 + + G + V F + + L S I+ G + + + G+LV Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 73 ARRGTRFVLLLGTAIVVGSIIWTVNARGPVSFLLAFGVLMSVG-LAFTSPVALTPVLTRW 131 RRG +VL +G + S + S+ + ++ +G L+FT V T V + Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 132 FTRRRGMALFFLSTGSMAGIA 152 + G + L+ S Sbjct: 378 KQQEAGAGMSLLNFTSFLSEG 398
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 346 bits (889), Expect = e-115 Identities = 134/392 (34%), Positives = 197/392 (50%), Gaps = 49/392 (12%) Query: 274 LRLGGRDWLANRMPIRERGAVVGAALTLYDAGRIHEADTSLRVQQRRRQNTAKYQFAELI 333 G D+L + E ++G AL + ++ + L+ Sbjct: 94 SEKGAYDYLPKPFDLTELIGIIGRAL-------------AEPKRRPSKLEDDSQDGMPLV 140 Query: 334 GRSPPFLRAVRTARRYAQTDLTVLIAGESGVGKELFAQAIHNESRRADRPFVAVNCASFP 393 GRS R R QTDLT++I GESG GKEL A+A+H+ +R + PFVA+N A+ P Sbjct: 141 GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIP 200 Query: 394 ESLLESELFGYEEGAFTGSRRGGKRGLFEAAHTGTLFLDEIGDMPLPLQSRLLRVLQERE 453 L+ESELFG+E+GAFTG++ G FE A GTLFLDEIGDMP+ Q+RLLRVLQ+ E Sbjct: 201 RDLIESELFGHEKGAFTGAQTRST-GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGE 259 Query: 454 VTRLGATAAIPVDVRIIAATHQPLSDMVAQRRFRQDLYYRINTLRLEVPPLRERPDDIQP 513 T +G I DVRI+AAT++ L + Q FR+DLYYR+N + L +PPLR+R +DI Sbjct: 260 YTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPD 319 Query: 514 LLETLIDRCLRRLGAPLQAAGLVAPWLPRLRRYAWPGNVRELENISERMAVF-------- 565 L+ + + + G L ++ + WPGNVRELEN+ R+ Sbjct: 320 LVRHFVQQ-AEKEGLD--VKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITR 376 Query: 566 -LMQYPHAADVDH----------------DALRHDCPELFEAGAAVAADEG-------RS 601 +++ +++ A+ + + F + G Sbjct: 377 EIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEM 436 Query: 602 QRDRALRALEACGGNRQEAARRLGISRSTLWR 633 + L AL A GN+ +AA LG++R+TL + Sbjct: 437 EYPLILAALTATRGNQIKAADLLGLNRNTLRK 468
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 2e-13 Identities = 35/173 (20%), Positives = 57/173 (32%), Gaps = 10/173 (5%) Query: 20 MKKRGRQPDPAKAQVILEAACSSFSHRGYFGTSMETIAACAHTTKATIYAKFDSKERLFA 79 +K ++ + IL+ A FS +G TS+ IA A T+ IY F K LF+ Sbjct: 2 ARKTKQEAQETRQH-ILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 80 AALEELERRM-PRPQDIMRCSGKDVLDDLLVIASRLLKLALHRSTLGIYRMLLLPIDHAP 138 E E + + D L L I +L+ + R LL+ I Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER----RRLLMEIIFHK 116 Query: 139 RLGAQFWQKIVEPYRKAMEEVLRDAH----RCQSLHIIDPRLASDHFFSLVIG 187 + + R E C ++ L + ++ G Sbjct: 117 CEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRG 169
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.010 Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 3/77 (3%) Query: 116 PLAAPADAAREPTRKRAELARSGPAALQEIADAIVKAATSAETKAERPVALALVRESVMR 175 P AD P+ E+AR A + A A + + ET AE + E + Sbjct: 1000 PNNIQADVPSVPSN-NEEIARVDEAPVPPPAPAT--PSETTETVAENSKQESKTVEKNEQ 1056 Query: 176 QPPEGYARNCEALAEAQ 192 E A+N E EA+ Sbjct: 1057 DATETTAQNREVAKEAK 1073
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 8e-16 Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 3/120 (2%) Query: 477 ILVVDDHAANRTLLKHQLQKLGHAVVCAENGLQALEAVGRQVFKLAICDCAMPRMNGMEF 536 ILV DD AA RT+L L + G+ V N + L + D MP N + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 537 VRALRAGPEPNARMPVLGYTAGAQDNYAQQAIDAGMDAVLFKPAGLAELQAALRAHLPQP 596 + ++ + +PVL +A A +A + G L KP L EL + L +P Sbjct: 66 LPRIK---KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 2e-18 Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 2/119 (1%) Query: 2 TSVLIVDDHPSLRLILRQQLSQMLGVSQIIEAGNGQDAVQAVRQHEPGLVILDIDLPKIN 61 ++L+ DD ++R +L Q LS+ + N + + + LV+ D+ +P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEAIPRIKLIKPDIRILVISAQDPVVFAPRVKAAGAQGYISKVQELPEIVRAIETVLA 120 + +PRIK +PD+ +LV+SAQ+ + A + GA Y+ K +L E++ I LA Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 1e-15 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 561 QTARVLAVDDHEPYRIILRQLMLRAGLNCDTVADAEQALEALRQHDYAMLFTDCQMPGID 620 A +L DD R +L Q + RAG + ++A + D ++ TD MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 621 GCELARRVRQQEAQAQRPRLPIVGVTADCSTQQMQRCRASGMDDYLAKP 669 +L R++ RP LP++ ++A + + G DYL KP Sbjct: 62 AFDLLPRIK-----KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.028 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 12/86 (13%) Query: 574 GYADKPAARPDDWSGRALPPVLPVSSDTDTSGLNEDGGLQIRPE--LDMLPTAAPLELEP 631 G A+ P A+P LP V P + + NE+ G + PE D+ P A P + Sbjct: 318 GSAEAPNAQP-------LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANP---DT 367 Query: 632 DLASMEEDDGPPLPVEPDRRLQRSAR 657 D D P +P P+ R ++ + Sbjct: 368 DGQPGTRPDSPAVPDRPNGRHRKERK 393
>YERSINIAYOPE#Yersinia virulence determinant YopE protein signature. Length = 219 Score = 28.5 bits (63), Expect = 0.025 Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 131 REDARRPVRLVSELGSRL--PAHACA--LGKALLAGLPEPVLA-----ETLPPVLVQVSE 181 R ++ + L S + RL AH+ + + G +PV+ +P Sbjct: 46 RTESPQGSSLASRIIERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDS 105 Query: 182 RTQTDRAAL---LRELAQARAEGLAQEHEEVAAG 212 Q L +++L AE L + H++ A G Sbjct: 106 IKQLAAETLPKYMQQLNSLDAEMLQKNHDQFATG 139
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 25.5 bits (56), Expect = 0.025 Identities = 9/31 (29%), Positives = 12/31 (38%) Query: 33 AGSIIVRQRGTRFHPGTNVGIGKDHTLFALI 63 AG II Q G F + + + A I Sbjct: 98 AGEIIGLQMGLSFATFVDPASHLNMPVLARI 128
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 27/106 (25%), Positives = 39/106 (36%), Gaps = 7/106 (6%) Query: 138 GVVPIVNENDTVVTDEIRLGDNDTLGALVTNLIEADALVILTDQRGLYDSDPRKNPDAVF 197 G VP++ E+ + E + D D G + + AD +ILTD G + + Sbjct: 195 GGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLR 253 Query: 198 VAHAQAGDPELEAMAGGAGSGIGTGGMLTKILAAKRAAHSGAHTVI 243 + E AGS M K+LAA R G I Sbjct: 254 EVKVEELRKYYEEGHFKAGS------MGPKVLAAIRFIEWGGERAI 293
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.008 Identities = 32/141 (22%), Positives = 53/141 (37%), Gaps = 4/141 (2%) Query: 1 MQAAIEAIVIQGGVPRRPHLSSALAAMGWSVRECSAVGGLGNLVDARPPQVMMLEGPAQM 60 M A +V R L+ AL+ G+ VR S L + A +++ + Sbjct: 1 MTGAT-ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 LCTLAGIARFTA--PRAALIVLADDTELEARVLALGAGADVACPLQIDLRE-LAALGRAL 117 + R P ++V++ + A GA P DL E + +GRAL Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 118 AQPRRDDVRPAAPVTPGWHLI 138 A+P+R + G L+ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLV 140
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 84.9 bits (210), Expect = 7e-20 Identities = 53/149 (35%), Positives = 81/149 (54%), Gaps = 5/149 (3%) Query: 13 VNVGTIGHVDHGKTTLTAAI--TTVLSTKFGGEARGYDQIDAAPEEKARGITINTAHVEY 70 +N+G + HVD GKTTLT ++ + T+ G +G + D E+ RGITI T + Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 ETESRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPY 130 + E+ +D PGH D++ + + +DGAIL++SA DG QTR R++G+P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP- 122 Query: 131 IIVFLNKADMVDDAELLELVEMEVRELLS 159 I F+NK D L V +++E LS Sbjct: 123 TIFFINKIDQN--GIDLSTVYQDIKEKLS 149
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 627 bits (1618), Expect = 0.0 Identities = 172/694 (24%), Positives = 297/694 (42%), Gaps = 77/694 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA ++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYGVPRLAFVNKMDRTGANFFKVYDQLKTRLRANPVPIVIPIGAEDSFKGVIDLVKM 188 K G+P + F+NK+D+ G + VY +K +L A V + V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIK----------QKVELYPNM 164 Query: 189 KAIIWDEASQGTKFDYVDIPAELEGAANEWREKLVEAAAESTEELMNKYLETGSLDEAEI 248 + E+ Q + E ++L+ KY+ SL+ E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 NTAIRQRTIAGEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPIDIPPVAGQDDEGNEISRK 308 R + P+ G+A N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 ADDGEKMSALAFKLMSDPFVGQLTFVRVYSGILKSGDTVYNPIKGKKERVGRLLQMHANN 368 ++ FK+ +L ++R+YSG+L D+V K K ++ + Sbjct: 244 -RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-KITEMYTSINGE 301 Query: 369 REEIKEVLAGDIAAVVG----LKDVTTGETLCDVDSHILLERMEFPEPVISQAVEPKSKA 424 +I + +G+I + L V G+T ER+E P P++ VEP Sbjct: 302 LCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSKPQ 356 Query: 425 DQEKMGLALSRLAQEDPSFRVRSDEESGQTIISGMGELHLEILVDRMKREFGVEANVGKP 484 +E + AL ++ DP R D + + I+S +G++ +E+ ++ ++ VE + +P Sbjct: 357 QREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEP 416 Query: 485 QVAYRETIRKTCEEVEGKFVKQSGGRGQYGHVVLKLEPLEPGGGYEFVDAIKGGVVPREY 544 V Y E K E + + + L + PL G G ++ ++ G + + + Sbjct: 417 TVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSF 473 Query: 545 IPAVDKGIQETLPAGILAGYPVVDVKATLFFGSYHDVDSNENAFKMAASMAFKEGMRKAS 604 AV +GI+ G L G+ V D K +G Y+ S F+M A + ++ ++KA Sbjct: 474 QNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAG 532 Query: 605 PVLLEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMEDMVGGGKTIKAEVPLAEMFGYAT 664 LLEP ++ ++ P++Y D + + + + E+P + Y + Sbjct: 533 TELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRS 591 Query: 665 NLRSLTQGRATYTMEFKHYSEAPKNVADEVIAAR 698 +L T GR+ E K Y + V R Sbjct: 592 DLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 5e-08 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 5/138 (3%) Query: 1 MKQLKVLIMVPDATVRGHSVMTMLQAGIAAEACGTPLELFKLLGEDQYDAVVLDIGELGE 60 M +L+ DA +R + +AG L++ + D VV D+ E Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 IGYALLSRLRA-SPVLGIVVIGAGLGIENRLRCLQSGADICLPDPVDSRELACVLLALAR 119 + LL R++ P L ++V+ A ++ + GA LP P D E L+ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE----LIGIIG 116 Query: 120 RLPGRASEEIAQAESAPE 137 R ++ E + Sbjct: 117 RALAEPKRRPSKLEDDSQ 134
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.8 bits (176), Expect = 1e-16 Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 1/131 (0%) Query: 7 EDDLDQARHIKQVLDSAGYTCHSYQRSRDLLAAVRNQSFDLIMLDWQLPDMDGDEVLRRL 66 +DD + Q L AGY + L + DL++ D +PD + ++L R+ Sbjct: 10 DDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRI 69 Query: 67 RSTLGMQVPIIFLTSRSQEIDLVQGLHAGADDYVVKPLRSAELLARIAALLRRSQAAQPD 126 + +P++ +++++ + ++ GA DY+ KP EL+ I L + Sbjct: 70 KK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSK 128 Query: 127 HAPFSVAGYDI 137 S G + Sbjct: 129 LEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 0.001 Identities = 21/105 (20%), Positives = 39/105 (37%), Gaps = 26/105 (24%) Query: 667 LLDNAIKY----SPDGSRIQLRVRAAAEMWDVEIEDAGPGIAPQDQQRLFQPFFRTGEAR 722 L++N IK+ P G +I L+ +E+E+ G ++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------- 309 Query: 723 RSSTGGAGLGLAFVRA-VALRHGGE--ITVHSERGSGTRFTLRLP 764 G GL VR + + +G E I + ++G + +P Sbjct: 310 -----STGTGLQNVRERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 4e-06 Identities = 55/316 (17%), Positives = 107/316 (33%), Gaps = 72/316 (22%) Query: 192 GRVIVQVAETLESRQDFLQRALVRAVERDIVVIAIVVLVVVWSVFMAVRPLERLRQEVEG 251 G V+ + RQ +L+ + + + V+ A VV+ +VW V + RL + Sbjct: 52 GLVLTHAYRSFIKRQGWLKLNMGQII--LRVLPACVVIGMVWFVANTS--IWRLLAFINT 107 Query: 252 RSADDLSPVDATNIPGEVGPL----VDAVNLHMARFAAQARLQRQFLDDASHQLRTPLSV 307 + P+ + I V + H + QA + + + + + + L Sbjct: 108 KPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQ--LMA 165 Query: 308 LRTQ-----------TAYALRESDPQEVRAVLLAMQEGLDRAVRTTNQMLALARAKDAPL 356 L+ Q AL DP + R +L ++ E + R + L + A+ L Sbjct: 166 LKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELM----RYS---LRYSNARQVSL 218 Query: 357 SEDGLAPERVDLAEVAQGVIRALLPAARAR-----QIDLGLEASSLPVCIPGVDWLLREA 411 ++ E+ + + L A + Q + + + + V +P Sbjct: 219 AD-----------ELTV--VDSYLQLASIQFEDRLQFENQINPAIMDVQVP------PML 259 Query: 412 LSNLVDNAIRY----TAPASQVTVRVYADERYARLTVEDNGPGMSAEDIARASVRFRRGA 467 + LV+N I++ ++ ++ D L VE+ G Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA---------------- 303 Query: 468 AGKNKPGAGLGLAIVR 483 K G GL VR Sbjct: 304 LKNTKESTGTGLQNVR 319
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.3 bits (224), Expect = 3e-23 Identities = 41/161 (25%), Positives = 75/161 (46%), Gaps = 4/161 (2%) Query: 2 RILLIEDEAELARWLSRSLARHAGFVVEWADDGLLAERRLAVEEFDAVILDLGLPGMDGH 61 IL+ +D+A + L+++L+R AG+ V + R +A + D V+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSR-AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 TLLSKIRARDDRTPVLVLTARDSLAERVGTLHEGADDFLPKPFVLEE-LEARLTALIRRS 120 LL +I+ PVLV++A+++ + +GA D+LPKPF L E + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 RGREHPRLAL--GDLILDTSAQRFTVRGQPLQLSPREHAVL 159 R G ++ SA + +L + ++ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 2e-06 Identities = 70/353 (19%), Positives = 116/353 (32%), Gaps = 52/353 (14%) Query: 56 TEFGLLAATPVLSGSLIRVPLGIWTDRYGGRIVFFLLMLVSVPGVWLLAYATEYWQFLVL 115 +G+L A L LG +DR+G R V + + + ++A A W + Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 116 GLFIGLAGGSFSVGTPYVA---------RWFPRNRQGLAMGIFGAGNSGSALTKFVA-PA 165 + G+ G + +V Y+A R F G FG G VA P Sbjct: 103 RIVAGITGATGAVAGAYIADITDGDERARHF-----GFMSACFGFG--------MVAGPV 149 Query: 166 LIAAAGGAWVIVPQVYAVALLATAILFWMF-------SATNPAHNVRGGASLSAQLAMLR 218 L GG P A AL L F P S + A Sbjct: 150 LGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM 209 Query: 219 DPRVWRYCQYYSVVFGGYVALALWMTKYYVGEYGFDMKLAALLAACFSLPGGVLRA-VGG 277 ++ + G V ALW+ + + +D + A F + + +A + G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVI-FGEDRFHWDATTIGISLAAFGILHSLAQAMITG 268 Query: 278 WISDKYGAYRTTWWVMWVCWVAFFLLSYPQTHFVIETDTGPREFFLAIGPTLFTILMFVV 337 ++ + G R M + LL+ F G F I++ + Sbjct: 269 PVAARLGERRALMLGMIADGTGYILLA-----------------FATRGWMAFPIMVLLA 311 Query: 338 GIAMAVGKASVFKFISDEFG-ENIGAVSGIVGLAGGLGGFVLPILFGALLDFT 389 + G ++ +S + E G + G + L V P+LF A+ + Sbjct: 312 SGGI--GMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.003 Identities = 23/105 (21%), Positives = 37/105 (35%), Gaps = 3/105 (2%) Query: 67 WLTALPALSGATLRIFYSFLVPVFGGR---RWTAISTATLLIPAIGMGFALQDPTTSYPT 123 W +S A I +S + G R L + A G G+ L T Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 124 LLALALLCGFGGGNFSSSMANISFFFPKEKKGFATGMNAGIGNLG 168 + +L GG + A +S +E++G G A + +L Sbjct: 303 AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT 347