>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.9 bits (64), Expect = 0.009 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 84 SQILDEAKAEAEQERTKIV---AQAQAEIDAERKRAREELR 121 QI +AK E R + V AQAQ + + R +EEL+ Sbjct: 319 EQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQ 359
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 29.9 bits (67), Expect = 0.001 Identities = 14/23 (60%), Positives = 16/23 (69%) Query: 1 MKRHAIYFALALAGAAFTLQAAP 23 MK+ AI A+ALAG A QAAP Sbjct: 1 MKKTAIAIAVALAGFATVAQAAP 23
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.5 bits (69), Expect = 0.013 Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 3/114 (2%) Query: 331 LTAVVVGILFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVKWSDLTEAVPA--- 387 L+ VV +L PL + A A ++ G L++ + + A Sbjct: 72 LSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRI 131 Query: 388 FITAVMMPFSFSITEGIALGFISYCVMKIGTGRLRELSPCVIIVSLLFVLKIVF 441 F ++ F SI + + L + + ++K L +L C I + +I+ Sbjct: 132 FSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILR 185
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 58.3 bits (141), Expect = 2e-11 Identities = 66/311 (21%), Positives = 118/311 (37%), Gaps = 14/311 (4%) Query: 5 LLCSFALVLLYPSGIDMYLVGLPRIAQDLGASEAQLHIAFSVYLAGMASAML----FAGR 60 L+ + V L GI + + LP + +DL S + + + LA A G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSN-DVTAHYGILLALYALMQFACAPVLGA 65 Query: 61 IADRSGRKPVAIVGAAIFVIASLLCAQAHTSSHFLIGRFIQGIGAGSCYVVAFAILRDTL 120 ++DR GR+PV +V A + + A A IGR + GI G+ VA A + D Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADIT 124 Query: 121 DDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKYPWQSLFYTMTGMGVMVAVLSVFILRE 180 D RA+ ++ V PVLG L M + + F+ + + + F+L E Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGL-MGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 181 TRPTAPPQAASPQHDAGESLLNRFFLSRLLITTLSVTVILTYVNVSPVLMMEEMGFDRGT 240 + + S + ++ ++V I+ V P + G DR Sbjct: 184 SHKGERRPLRREALNPLASFRWARGM-TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 241 YSMAM------ALMAMISMAVSFSTPFALSLFNPRTLMLTSQVLFLAAGVTLSLATRQAV 294 + A + S+A + T + R ++ + + L+ ATR + Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 295 TLIGLGMICAG 305 + ++ +G Sbjct: 303 AFPIMVLLASG 313
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.0 bits (88), Expect = 3e-06 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Query: 69 IVDVAVDPAHQGKGLGRLVMEKLVAWLDANAFDGAYV-TLVADVP--ELYAKFGF 120 I D+AV ++ KG+G ++ K + W N F G + T ++ YAK F Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 787 bits (2034), Expect = 0.0 Identities = 461/532 (86%), Positives = 493/532 (92%), Gaps = 2/532 (0%) Query: 1 MIWQAWEQDKNPQPQ-QQTTQTTTTAAGSAADQGVPASGQGKLITVKTDVLELTINTNGG 59 MIWQAWEQDKNPQPQ QQTTQTTTTAAGSAADQGVPASGQGKLI+VKTDVL+LTINT GG Sbjct: 18 MIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGG 77 Query: 60 DIEQALLLAYPKTLKSTEPFQLLETTPQFVYQAQSGLTGRDGPDNPANGPRPLYNVDKEA 119 D+EQALL AYPK L ST+PFQLLET+PQF+YQAQSGLTGRDGPDNPANGPRPLYNV+K+A Sbjct: 78 DVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDA 137 Query: 120 FVLADGQDELVIPLTYTDKAGNVFTKTFTLKRGGYAVNVGYSVQNASEKPLEVSTFGQLK 179 +VLA+GQ+EL +P+TYTD AGN FTKTF LKRG YAVNV Y+VQNA EKPLE+S+FGQLK Sbjct: 138 YVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLK 197 Query: 180 QTAALPTSRDTQTGGLSTMHTFRGAAFSTADSKYEKYKFDTILDNENLNVSTKNGWVAML 239 Q+ LP DT + + +HTFRGAA+ST D KYEKYKFDTI DNENLN+S+K GWVAML Sbjct: 198 QSITLPPHLDTGSSNFA-LHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAML 256 Query: 240 QQYFTTAWVPRNNGTNNFYTANLGNGIVAIGYKSQPVLVQPGQTDKLQSTLWVGPAIQDK 299 QQYF TAW+P N+GTNNFYTANLGNGI AIGYKSQPVLVQPGQT + STLWVGP IQDK Sbjct: 257 QQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDK 316 Query: 300 MAAVAPHLDLTVDYGWLWFISQPLFKLLKFIHSFLGNWGFSIIVITFIVRGIMYPLTKAQ 359 MAAVAPHLDLTVDYGWLWFISQPLFKLLK+IHSF+GNWGFSII+ITFIVRGIMYPLTKAQ Sbjct: 317 MAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQ 376 Query: 360 YTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLAL 419 YTSMAKMRMLQPKIQAMRERLGDDKQR SQEMMALYKAEKVNPLGGCFPL+IQMPIFLAL Sbjct: 377 YTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLAL 436 Query: 420 YYMLSASVELRHAPFILWIHDLSAQDPYYILPIIMGATMFFIQKMSPTTVTDPMQQKIMT 479 YYML SVELR APF LWIHDLSAQDPYYILPI+MG TMFFIQKMSPTTVTDPMQQKIMT Sbjct: 437 YYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMT 496 Query: 480 FMPVIFTVFFLWFPSGLVVYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS 531 FMPVIFTVFFLWFPSGLV+YYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS Sbjct: 497 FMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS 548
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 69.5 bits (170), Expect = 4e-15 Identities = 80/339 (23%), Positives = 132/339 (38%), Gaps = 25/339 (7%) Query: 27 LPALPEITQQLQATSTQTQLSLTAALIGLGLGQLFFGP----LSDRIGRLKPLALSLLLF 82 +P LP + + L S L L Q P LSDR GR L +SL Sbjct: 25 MPVLPGLLRDLVH-SNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83 Query: 83 IFSSAMCALTRDINMLIVWRFLQGFAGAGGSVLSRSIARDKYQGTLLTQFFALLMTVNGI 142 A+ A + +L + R + G GA G+V IA D G + F + G Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITDGDERARHFGFMSACFGF 142 Query: 143 APVLSPVLGGYVITAFDWRILFWTMAAIGGVLLVMSLAILRETRPATAAHASRQRPGQPV 202 V PVLGG + F F+ AA+ G+ + +L E+ R+ Sbjct: 143 GMVAGPVLGGL-MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNP-- 199 Query: 203 LKNRRFLRFCLIQAFMMA-----GLFSYIGSSSFVMQSE--YGMSAMQFSLLFGLNGI-G 254 L + R+ R + A +MA L + ++ +V+ E + A + GI Sbjct: 200 LASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILH 259 Query: 255 LIIAAMIFSRLARRFSAESLLRGGLTLAVSCAAIMLLFA---WLHLPVLALVGL--FFTV 309 + AMI +A R L G+ +A I+L FA W+ P++ L+ Sbjct: 260 SLAQAMITGPVAARLGERRALMLGM-IADGTGYILLAFATRGWMAFPIMVLLASGGIGMP 318 Query: 310 SLMSGISTVAGAEAMSAVDAAQSG--TASALMGTLMFVF 346 +L + +S E + + + + ++++G L+F Sbjct: 319 ALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1145 bits (2963), Expect = 0.0 Identities = 583/1031 (56%), Positives = 754/1031 (73%), Gaps = 6/1031 (0%) Query: 3 SRFFVRRPVFAWVIAILIMLAGVLAIRTLPVGQYPDVAPPAVKISATYTGASAETLENSV 62 + FF+RRP+FAWV+AI++M+AG LAI LPV QYP +APPAV +SA Y GA A+T++++V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 63 TQVIEQQLTGLDHLLYFSSTSSSDGSVSITVTFEQGTDPDTAQVQVQNKVQQAESRLPSE 122 TQVIEQ + G+D+L+Y SSTS S GSV+IT+TF+ GTDPD AQVQVQNK+Q A LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 VQQSGVTVEKSQSSFLLILAVYDKTNRATSSDISDWLVSNMQDPLARVEGVGSLQVFGAE 182 VQQ G++VEKS SS+L++ T DISD++ SN++D L+R+ GVG +Q+FGA+ Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ 181 Query: 183 YAMRVWMDPTKLASYSLMPSDVQSAIEAQNVQVSAGKIGALPSSNAQQLTATVRAQSRLQ 242 YAMR+W+D L Y L P DV + ++ QN Q++AG++G P+ QQL A++ AQ+R + Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 243 TPDQFKAIIVKSQADGSVVRLSDVARVEMGSEDYTATANLNGHPAAGIAVMMAPGANALD 302 P++F + ++ +DGSVVRL DVARVE+G E+Y A +NG PAAG+ + +A GANALD Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 303 TATLVKSKIAEFQRQMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIILVVCVMYLFLQN 362 TA +K+K+AE Q PQG + YP D+T F+++S+ +V++TLFEAI+LV VMYLFLQN Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 363 FRATLIPAVAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMR 422 RATLIP +AVPVVLLGTF +LA FGYSINTLT+F MVLAIGLLVDDAIVVVENVER+M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 423 DEGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSVTIISAMMLS 482 ++ LP +EATEKSM +I GALV IA+VLSAVF+PMAFFGGSTG IYRQFS+TI+SAM LS Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 483 VVVALTLTPALCGALL----SHSKPHTKGFFGAFNRLWGRTEAGYQRRVLGGLRRGAVMM 538 V+VAL LTPALC LL + + GFFG FN + + Y V L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 539 GAYALICGAMALAMWKLPGSFLPVEDQGEIMVQYTLPAGATAVRTAEVRRQVTDWFLTKE 598 YALI M + +LP SFLP EDQG + LPAGAT RT +V QVTD++L E Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 599 KANTDVIFTVDGFSFSGSGQNAGMAFVSLKNWSQRKGDDNTAQAIALRATKELGTIRDAT 658 KAN + +FTV+GFSFSG QNAGMAFVSLK W +R GD+N+A+A+ RA ELG IRD Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 659 LFAMTPPSVDGLGQSNGFTFELMASGGTDRDSLMKLRSQLLAAANQS-SELQSVRANDLP 717 + P++ LG + GF FEL+ G D+L + R+QLL A Q + L SVR N L Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 718 QMPQLQVDIDNNKAVSLGLSLSDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGESDARAV 777 Q ++++D KA +LG+SLSD+ T+S+A GGTYVNDFIDRGRVKK+Y+Q ++ R + Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 778 PSDLGKWFVRGSDNSMTPFSAFATTHWQYGPESLVRYNGSAAFEIQGENAAGFSSGAAMD 837 P D+ K +VR ++ M PFSAF T+HW YG L RYNG + EIQGE A G SSG AM Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 838 KMEKLADSLPAGSTWAWSGISLQEKLASGQAMSLYAISILVVFLCLAALYESWSVPFSVI 897 ME LA LPAG + W+G+S QE+L+ QA +L AIS +VVFLCLAALYESWS+P SV+ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 898 MVIPLGLLGAALAATLRGLSNDVYFQVALLTTIGLSSKNAILIVEFAESAVD-EGYSLSR 956 +V+PLG++G LAATL NDVYF V LLTTIGLS+KNAILIVEFA+ ++ EG + Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 957 AAIRAAQTRLRPIVMTSLAFIAGVLPLAIATGAGANSRVAIGTGIIGGTLTATLLAVFFV 1016 A + A + RLRPI+MTSLAFI GVLPLAI+ GAG+ ++ A+G G++GG ++ATLLA+FFV Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 1017 PLFFVLVKRLF 1027 P+FFV+++R F Sbjct: 1022 PVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 2e-06 Identities = 24/133 (18%), Positives = 51/133 (38%), Gaps = 10/133 (7%) Query: 8 PVPVVSQLTGRTTAS-LSAEVRPQVGGIIQKRLFTEGDMVKAGQALYQIDPSSYRATWNE 66 V +V+ G+ T S S E++P I+++ + EG+ V+ G L ++ A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 67 AAAALKQAQALVASDCQKAQRYASLVRDNGVSRQDADDAASTCAQDKASV--------ES 118 ++L QA+ Q R L + + D + ++ + + Sbjct: 139 TQSSLLQARLEQTRY-QILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 119 KKAALESARINLN 131 + +NL+ Sbjct: 198 WQNQKYQKELNLD 210
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 51 GLIAKRKGNW---LCIEYLWVSETTRGRGLGSELMQEAEQQAQAQGCSHLLVDTFSFQ-- 105 G I R NW IE + V++ R +G+G+ L+ +A + A+ L+++T Sbjct: 78 GRIKIRS-NWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINIS 136 Query: 106 ALPFYQKLGYQL 117 A FY K + + Sbjct: 137 ACHFYAKHHFII 148
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.1 bits (179), Expect = 4e-18 Identities = 33/175 (18%), Positives = 70/175 (40%), Gaps = 10/175 (5%) Query: 12 RPGRPRGKKPGTANREQLMDIALTLFARDGAGRVSLNAIAKEAGVTPAMLHYYFSSRDAL 71 R + ++ R+ ++D+AL LF++ G SL IAK AGVT ++++F + L Sbjct: 3 RKTKQEAQE----TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDL 58 Query: 72 VTQLIEERFMPLRNHISRIFVDHPQDPVL----ALTMMVETLGHMAEKNAWFAPLWM-QE 126 +++ E + P DP+ L ++E+ + ++ E Sbjct: 59 FSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 127 IIGEMPILRQHMDARFGEERFQVMLGTVRRWQQEGKINPALAPELLFTTVISLVL 181 +GEM +++Q E + + T++ + + L + + Sbjct: 119 FVGEMAVVQQ-AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 138 bits (350), Expect = 4e-38 Identities = 94/418 (22%), Positives = 178/418 (42%), Gaps = 19/418 (4%) Query: 20 LLLVMLLSALDQTIVSTALPTIVGELGGL-DKLSWVVTAYILSSTIAVPLYGKFGDLFGR 78 L ++ S L++ +++ +LP I + +WV TA++L+ +I +YGK D G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 79 KIVLQVAIGLFLVGSALCGLAQNMTQLVLM-RGLQGLGGGGLMVISMAAVADVIPPANRG 137 K +L I + GS + + + L++M R +QG G + M VA IP NRG Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 138 RYQGLFGGVFGLATVIGPLIGGFLVQHASWRWIFYINLPLGLFALLVIGAVFHSSNKRSQ 197 + GL G + + +GP IGG + + W ++ +P+ + R + Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIK 196 Query: 198 HQIDWLGAIYLSMALLCIILFTSEGGSVHAWNDPQLWCILAFGIVGIIGFIYEERMAAEP 257 D G I +S+ ++ +LFT+ L ++ + F+ R +P Sbjct: 197 GHFDIKGIILMSVGIVFFMLFTTS----------YSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 258 IIPLALFRNRSFLLCSLIGFVIGMSLFGSVTFLPLYLQVVKEATPTEAGLQLI-PLMGGL 316 + L +N F++ L G +I ++ G V+ +P ++ V + + E G +I P + Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 317 LLTSIISGRIISRTGKYRLFPILGTLLGVTGMVLLTRITIHSPLWQLYLFTGVLGAGLGL 376 ++ I G ++ R G +G + + + + + + VLG GL Sbjct: 307 IIFGYIGGILVDRRGP-LYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSF 364 Query: 377 VMQVLVLAVQNAMPAQMYGVATSGATLFRSIGGSIGVALFGAVFTHVLQSNLQQLLPE 434 V+ V +++ Q G S + G+A+ G + + + Q+LLP Sbjct: 365 TKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS--IPLLDQRLLPM 420
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 57.9 bits (140), Expect = 1e-11 Identities = 48/351 (13%), Positives = 121/351 (34%), Gaps = 85/351 (24%) Query: 21 IERILINKGDNVAAGQELVKIESFDA-------QNIFLRAEEKLSAESALLRNLESGERP 73 ++ I++ +G++V G L+K+ + A Q+ L+A + + L R++E + P Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLP 166 Query: 74 E-----------------------------------------------ELDIIRSQIKKA 86 E E + ++I + Sbjct: 167 ELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRY 226 Query: 87 QSAESQVKRQLGRYRNLYANHAISLAEWEDIRDELTQKGAQVEEL---INQLKARQLPAR 143 ++ K +L + +L AI+ + ++ + ++ + Q+++ L A+ Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 144 Q--------------DEISKQRSMVAAAKLERDKALWDVQQTTIVSPVNAKVFDI-IYRA 188 + D++ + + LE K Q + I +PV+ KV + ++ Sbjct: 287 EEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTE 346 Query: 189 GERPSAGKPIISLLPPEN-IKVRFFIPEAKLGKFKIGSKVKLICDG----CAEPIAGVIN 243 G + + ++ ++P ++ ++V + +G +G + + + G + Sbjct: 347 GGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVK 406 Query: 244 YISPEA---EFTPPVIYSTKRREKLIFMAEAIPALQQAGRMKIGQPFDVEI 291 I+ +A + V E+ + + + G EI Sbjct: 407 NINLDAIEDQRLGLVFNVIISIEE-----NCLSTGNKNIPLSSGMAVTAEI 452
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.002 Identities = 21/105 (20%), Positives = 33/105 (31%), Gaps = 7/105 (6%) Query: 72 RQVEAAVAAAPTSDPVVSAASAA------PATSQPVVETAAAAPEPVRQEPAPTPAPSIP 125 V+ A +DP V+ T QP ET++ +PV + S+ Sbjct: 1137 ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV 1196 Query: 126 ASEPAMAPPPRMAPRPAPAAENYAHLFAAKSAEPVAKNKDQPLKS 170 + P P P + N +S V N + S Sbjct: 1197 EN-PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS 1240 Score = 27.7 bits (61), Expect = 0.033 Identities = 18/128 (14%), Positives = 39/128 (30%), Gaps = 8/128 (6%) Query: 43 NPGAEKSSSLALGGSVSAPLPQSVPADLFRQVEAAVAAAPTSDPVVSAASAAPATSQPVV 102 N + + + A + ++ +A V T + + +P Q Sbjct: 1079 NTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET 1138 Query: 103 ETAAAAPEPVRQEPAPTPAPSIPASEPAMAPPPRMAPRPAPAAENYAHLFAAKSAEPVAK 162 A EPA P++ EP + A PA E +++ + Sbjct: 1139 VQPQA-------EPARENDPTVNIKEPQ-SQTNTTADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 163 NKDQPLKS 170 + +++ Sbjct: 1191 TGNSVVEN 1198
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 30.3 bits (68), Expect = 0.035 Identities = 13/60 (21%), Positives = 21/60 (35%) Query: 277 GYANLNSGNTAAAKQQFEEVLQTNPQDADALAGMGYIAQRSGDYQAASQYLSRAADLGGD 336 + SG A + F+ + + D+ G+G Q G Y A S A + Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.045 Identities = 8/44 (18%), Positives = 17/44 (38%), Gaps = 5/44 (11%) Query: 93 QGSQIAGFSASYIWDLIVRFINWSMVGAFFVLLVLWLFISQWLR 136 G ++ + D ++ W VL+V W+ + +R Sbjct: 442 TGGELPFWQQQSFIDQLLAAGRW-----LLVLVVAWILWRKAVR 480
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 27.1 bits (60), Expect = 0.004 Identities = 10/47 (21%), Positives = 19/47 (40%), Gaps = 5/47 (10%) Query: 1 MHHVSPEYSQKAAFILEMRFSSHYARQVKK-----IMERCFNMIDQQ 42 M SPE ++ +LE + +S + + NM D++ Sbjct: 174 MDRTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRK 220
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.008 Identities = 79/365 (21%), Positives = 126/365 (34%), Gaps = 59/365 (16%) Query: 79 IGSALFGHFGDRVGRKVTLVASLLTMGISTVVIGLLPGYEIIGIVAPMLLALARFGQGLG 138 IG+A++G D++G K LL GI G + G+ +G LL +ARF QG G Sbjct: 64 IGTAVYGKLSDQLGIK-----RLLLFGIIINCFGSVIGF--VGHSFFSLLIMARFIQGAG 116 Query: 139 LGGEWGGAALLATENAPARKR----ALYGSFPQLGAPIGFFFANGTFLLLSW-------- 186 ++ P R L GS +G +G + W Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 187 -----LLTDQQFMEWGWRV--PF-IFSAVLVIIG-------------LYVRVSLHETPVF 225 + + ++ R+ F I +L+ +G ++ VS+ +F Sbjct: 177 ITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236 Query: 226 AKVAAAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTGAAPNGLGL 285 K + G + VL I+ T F M Y M + +G Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIG- 295 Query: 286 PRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMII-ITTMIILFALFAFKPLLGSGN 344 + +++ M+VI FG + G+L D G + I +T + + F +F S Sbjct: 296 --SVIIFPGTMSVIIFG---YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWF 350 Query: 345 PLLVFAFLLLGLSLMGL---TFGPMGALLPELFPTEVRYTGASFS-YNVSSILGASVAPY 400 ++ F+L GLS T L E GA S N +S L Sbjct: 351 MTIIIVFVLGGLSFTKTVISTIVSSS-----LKQQEA---GAGMSLLNFTSFLSEGTGIA 402 Query: 401 IAAWL 405 I L Sbjct: 403 IVGGL 407 Score = 29.5 bits (66), Expect = 0.026 Identities = 19/101 (18%), Positives = 38/101 (37%), Gaps = 2/101 (1%) Query: 255 FIMLATYTLFYIMTVYSMTFSTGAAPNGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADA 314 I L + F ++ + S N P W+ ++ F + V G L+D Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 315 FGRRKSMIIITTMIILFALFAFKPLLGSGNPLLVFAFLLLG 355 G ++ ++ + ++ F + S LL+ A + G Sbjct: 76 LGIKRLLLFGIIINCFGSVIGF--VGHSFFSLLIMARFIQG 114
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 30.1 bits (67), Expect = 0.015 Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 6/40 (15%) Query: 19 EKSKSTLEALNDTAVGQKASQALKTVTGTAAKVQRNPVIA 58 EK+K LE + TA+ LKTVTGT NPV A Sbjct: 273 EKAKQYLEEFHQTALEHPELSELKTVTGT------NPVFA 306
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.1 bits (210), Expect = 7e-22 Identities = 67/258 (25%), Positives = 113/258 (43%), Gaps = 16/258 (6%) Query: 4 RIALVTGGSRGLGKNAALKLAAKGTDILLTYHSNRQAALDVVAEIEQKGVKAAALALNVG 63 +IA +TG ++G+G+ A LA++G I N + VV+ ++ + A A +V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 64 DSTTFDAFASEVAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDELMNIQFKGPF 123 DS D E+ + ++ G D L+N AG+ S+ +++ ++ G F Sbjct: 68 DSAAID----EITARIEREMGP--IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 124 FLTQRLLPLLQD--GGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGIS 181 ++ + + D G I+ V S A AAYA+ K A + T+ EL I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 VNIIAPGAIETDFGGG-EVRDNAE--VNRHIAAQTALG----RVGLPDDIGDAIAALLSD 234 NI++PG+ ETD +N V + G ++ P DI DA+ L+S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 235 ELAWMNAQRVEVSGGMFL 252 + + + V GG L Sbjct: 242 QAGHITMHNLCVDGGATL 259
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.011 Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 5/97 (5%) Query: 182 TFIPILANTFARRAVEIPVMHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSIFGS 241 P L T + + FG +F +N + V + + R L I+ Sbjct: 487 ILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYAL 546 Query: 242 VIALLGFAFGLLLVVLRLAFGPQWAAEGVFMLFAVLF 278 ++A + F L +F P+ +GVF+ L Sbjct: 547 IVAGMVVLFLRLPS----SFLPE-EDQGVFLTMIQLP 578
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 108 bits (272), Expect = 5e-28 Identities = 73/361 (20%), Positives = 137/361 (37%), Gaps = 60/361 (16%) Query: 317 RVLILGVNGFIGNHLTERLLQDDNYEIYGLDIGSD--------AISRFLDCPRFHFVEGD 368 + L+ G GFIG H+++RLL + +++ G+D +D A L P F F + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLL-EAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 369 ISIHSEWIE--YHIKKCDVVLPLVAIATPIEYT-RNPLRVFELDFEENLKIIRDCVKYN- 424 ++ E + + + V + Y+ NP + + L I+ C Sbjct: 61 LADR-EGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 425 KRIIFPSTSEVYGMCTDKNFDEDSSNLVVGPINKQRWIYSVSKQLLDRVIWAYGDKNGLK 484 + +++ S+S VYG+ F D S V P++ +Y+ +K+ + + Y GL Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDS--VDHPVS----LYAATKKANELMAHTYSHLYGLP 172 Query: 485 FTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIEGGKQKRCFTDISDGI 544 T R F GP A+ + ++EG I + GK KR FT I D Sbjct: 173 ATGLRFFTVYGPWGR--------PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIA 224 Query: 545 EALFRIIEN---------------KDGRCDGQIINIGNPDNEASIKELAEMLLACFERHP 589 EA+ R+ + ++ NIGN + + + L Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVE-LMDYIQALEDALGIEA 283 Query: 590 LRDRFPPFAGFREVESSDYYGKGYQDVEHRKPSIRNAKRCLNWEPKVEMEETVEHTLDFF 649 ++ P G DV + + + P+ +++ V++ ++++ Sbjct: 284 KKNMLPLQPG---------------DVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328 Query: 650 L 650 Sbjct: 329 R 329
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 32.2 bits (73), Expect = 2e-04 Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 35 RHILFWLGMALLCLGCGMLLW-LSVLQSIPVS 65 R ILF+L M L C M+ W + + + PVS Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPVS 46
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.7 bits (111), Expect = 1e-07 Identities = 74/365 (20%), Positives = 133/365 (36%), Gaps = 30/365 (8%) Query: 13 LRLNLRIVSVVIFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 70 ++ N ++ ++ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADLLGPKKIVVFGLGGCFLSGLSYLLAAWGSGWPLISLLLLCLGRVILGI-GQS 129 P G +D G + +++ L + + Y + A L +L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSL---AGAAVDYAIMATAP-----FLWVLYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVLC--YSHIGLSGLAGVIM 187 A G+ + + R + M G LG L +S A + Sbjct: 113 GAVAGAYIADITDGDER--ARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALN 170 Query: 188 AVALVAILCALP-------RAAVKAAKGKAMSFR-AVLGRVWPYGMALA-LASAGFGVIA 238 + + LP R + A SFR A V MA+ + V A Sbjct: 171 GLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPA 230 Query: 239 TFITLFYDAK-GWDGAAFALTLFSCAFVGA---RLLFPNAINLLGGLNVAMLCFSVEAIG 294 +F + + WD ++L + + + ++ LG ML + G Sbjct: 231 ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTG 290 Query: 295 LLLVGFADTPMMAKIGTFLTGAGFSLVFPALGVVAVKAVPQHNQGSALATYTVFMDLSLG 354 +L+ FA MA L A + PAL + + V + QG + L+ Sbjct: 291 YILLAFATRGWMAFPIMVLL-ASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT-S 348 Query: 355 VSGPL 359 + GPL Sbjct: 349 IVGPL 353
>PF01206#SirA family protein Length = 76 Score = 103 bits (259), Expect = 3e-33 Identities = 27/71 (38%), Positives = 43/71 (60%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRTMPVGETLLIIADDPATTRDIPGFCRFMEHELVAQET 68 D +LDA GL CP P++ +KT+ TM GE L ++A DP + +D F + HEL+ Q+ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 EALPYRYLIRK 79 E Y + +++ Sbjct: 65 EDGTYHFRLKR 75
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.9 bits (67), Expect = 0.026 Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 160 ADPNSPQYNVIAATLMKVGQQAFSIMVPVFTAYIAWSISGRPGMVAGFVGGLLANATGAG 219 D + + A Q + +P+ TA + + G V+ + L++ Sbjct: 357 QDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSF---- 412 Query: 220 FLGGIIAGFAAGYFMLLIRHL 240 GI AGF G + +L+ L Sbjct: 413 --NGIAAGFYQGNWAMLLTAL 431
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 8e-07 Identities = 65/394 (16%), Positives = 120/394 (30%), Gaps = 57/394 (14%) Query: 46 KELGLS---AVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYSYSLFFWSLFTFLQGF 102 ++L S G + + + G L D+FG + V SL ++ + Sbjct: 33 RDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMAT 92 Query: 103 IDVFPLAWAGVSMFFMRFMLGFSEAPSFPANARIVAAWFPAKER----GTASAIFNAAQY 158 + + G R + G + A +A ER G SA F Sbjct: 93 APFLWVLYIG------RIVAGITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFG-- 143 Query: 159 FSLALFSPLLGWLTFALGWEHVF---TVMGIIGFVLTIIWVKFVHNPTDHPRMSAAELKY 215 + P+LG L F + + F+ + H P Sbjct: 144 ---MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP--------- 191 Query: 216 ISEGGAVVDMDHKKEATPAAGPKMDYIRQLLTNRMMLGVFFGQYFLNTITWFFLTWFPIY 275 + + R + ++ VFF + + + I+ Sbjct: 192 ------------LRREALNPLASFRWARGMTVVAALMAVFFI---MQLVGQVPAALWVIF 236 Query: 276 LVQDKGMSILKVGFVASIPALFGFAGGVLGGLFSDYLIGRGCTLTFARKLPIVLGMLL-A 334 +G + A G+L L + G + ++LGM+ Sbjct: 237 GEDRFHWDATTIGISLA-------AFGILHSLAQAMITGP-VAARLGERRALMLGMIADG 288 Query: 335 SSIILCNYTASTPLVITLMA-LAFFGKGFGALGWPVISDVAPKEIVGLCGGVFNVFGNVA 393 + IL + + +M LA G G AL ++S +E G G ++ Sbjct: 289 TGYILLAFATRGWMAFPIMVLLASGGIGMPALQ-AMLSRQVDEERQGQLQGSLAALTSLT 347 Query: 394 SIATPLVIGYIVSELHSFNGALIFVGGSALMMMV 427 SI PL+ I + + ++ G+AL ++ Sbjct: 348 SIVGPLLFTAIYAASITTWNGWAWIAGAALYLLC 381
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 37.1 bits (86), Expect = 8e-05 Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 12/82 (14%) Query: 144 KNISILVQIESQTGVDNVEAIAATEGVDGVFVGPSDLA----------AALGHLGNAAHP 193 +I + + +E + A + VD +G +DL + +L HP Sbjct: 423 DSIEVGIMVEIPSTAVAANLFA--KEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHP 480 Query: 194 EVQRAIQHIFASAKKHGKPSGI 215 + R + + +A GK G+ Sbjct: 481 AILRLVDMVIKAAHSEGKWVGM 502
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 2e-16 Identities = 35/157 (22%), Positives = 59/157 (37%), Gaps = 1/157 (0%) Query: 846 ILIADDHPTNRLLLKRQLSTIGYSVDEACDGEEAENKLASKHYDLLITDLNMPKKDGLAL 905 IL+ADD R +L + LS GY V + +A+ DL++TD+ MP ++ L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 906 AASLRRRYPGLVIWGVTASALPQSREACLASGMNMCLFKPVSVQTLSHELSRLAVGRASP 965 +++ P L + ++A + G L KP + + A+ Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE-LIGIIGRALAEPKR 124 Query: 966 HATRHLKLSVLSENTGGDQALMNEMLETFRDASAADL 1002 ++ S G A M E+ DL Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDL 161
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 4e-13 Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 1/114 (0%) Query: 4 IIIDDHPLARIAIRNLLDSNGITVAAELDSGAHAVQTAESMQPDLLIVDVDIPELSGIEV 63 ++ DD R + L G V + A + + DL++ DV +P+ + ++ Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LEQLRKRRYQGTIIIISAKNELFYGKRSADCGANGFVSKKEGMNNILAAIDAAN 117 L +++K R ++++SA+N ++++ GA ++ K + ++ I A Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1085 bits (2809), Expect = 0.0 Identities = 411/566 (72%), Positives = 474/566 (83%), Gaps = 2/566 (0%) Query: 4 ISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQML-A 62 +SR AYA+MFGPTVGDKVRLADTEL+IEVE D TT+GEEVKFGGGKVIRDGMGQ Q+ Sbjct: 5 MSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTRE 64 Query: 63 ADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGASTEVIAAE 122 VD V+TNALI+DHWGIVKADIG+KDGRI AIGKAGNPD+QP VTI +G TEVIA E Sbjct: 65 GGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGE 124 Query: 123 GKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTGPAAGTHATTCTPGPWYISRMLQ 182 GKIVTAGG+D+HIH+ICPQQ EEAL+SG+T M+GGGTGPA GT ATTCTPGPW+I+RM++ Sbjct: 125 GKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIE 184 Query: 183 AADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMDIQ 242 AAD+ P+N+ GKGN S P AL E V G LK+HEDWG TPAAIDC L+VADE D+Q Sbjct: 185 AADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDVQ 244 Query: 243 VALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTL 302 V +H+DTLNESGFVEDT+AAI GRTIH +HTEGAGGGHAPDII C PN++PSSTNPT Sbjct: 245 VMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTR 304 Query: 303 PYTLNTIDEHLDMLMVCHHLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQ 362 PYT+NT+ EHLDMLMVCHHL P I ED+AFAESRIR+ETIAAED+LHD+GAFS+ SSDSQ Sbjct: 305 PYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQ 364 Query: 363 AMGRVGEVILRTWQVAHRMKVQRGALAEETGDNDNFRVKRYIAKYTINPALTHGIAHEVG 422 AMGRVGEV +RTWQ A +MK QRG L EETGDNDNFRVKRYIAKYTINPA+ HG++HE+G Sbjct: 365 AMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEIG 424 Query: 423 SIEVGKLADLVVWSPAFFGVKPATVIKGGMIAIAPMGDINASIPTPQPVHYRPMFGALGS 482 S+EVGK ADLV+W+PAFFGVKP V+ GG IA APMGD NASIPTPQPVHYRPMFGA G Sbjct: 425 SLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYGR 484 Query: 483 ARHHCRLTFLSQAAAANGVAERLNLRSAIAVVKGCR-TVQKADMVHNSLQPNITVDAQTY 541 +R + +TF+SQA+ G+A RL + + V+ R + KA M+HNSL P+I VD +TY Sbjct: 485 SRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPETY 544 Query: 542 EVRVDGELITSEPADVLPMAQRYFLF 567 EVR DGEL+T EPA VLPMAQRYFLF Sbjct: 545 EVRADGELLTCEPATVLPMAQRYFLF 570
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 27.3 bits (60), Expect = 0.016 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 11/66 (16%) Query: 12 ITTIGVYDWEQTIEQK----LVFDI-EIAWDNRKAAASDDVSDCLSYADISERVIAHVEG 66 I IG+ D++ E K L F+I E A+ A A LS D S+RV+A G Sbjct: 148 IKIIGI-DFDIETEYKWFYSLQFNIKESAFTTGYAIA-----SWLSEQDESKRVVASFGG 201 Query: 67 GKFALV 72 G F V Sbjct: 202 GAFPGV 207
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 42.3 bits (99), Expect = 4e-07 Identities = 26/132 (19%), Positives = 48/132 (36%), Gaps = 7/132 (5%) Query: 30 GRTRGDYQVDITSQESVEA----LFAQTGEVDAIVSTTGNLHFGPLSTMTDSQFNLGLQD 85 R + D+ +++ + + G +D +V+ G L G + +++D ++ Sbjct: 56 ARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSV 115 Query: 86 KLLGQIRL--ALVGQHFLRDGGSITLVSGIVAQEPIAQGVNATTVNAGLEGFVRAAACEL 143 G ++ R GSI V A P + A F + EL Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 144 -PRGIRINLISP 154 IR N++SP Sbjct: 176 AEYNIRCNIVSP 187
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.5 bits (66), Expect = 0.003 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 65 LAVDKSLHGKGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDE--ARDFYLRVGFEPSP 122 +AV K KGVG AL+ A I+ A+ G+++ A FY + F Sbjct: 95 IAVAKDYRKKGVGTALLHKA----IEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150 Query: 123 MDPMM 127 +D M+ Sbjct: 151 VDTML 155
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 37.2 bits (86), Expect = 5e-05 Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 3/34 (8%) Query: 154 IYEEQFERKVTQQELADLLTGEGYRVTQSNISRM 187 I + E TQ EL D+L +GY VTQ+ +SR Sbjct: 14 ITANEIE---TQDELVDILKKDGYNVTQATVSRD 44
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.001 Identities = 14/123 (11%), Positives = 43/123 (34%), Gaps = 5/123 (4%) Query: 25 IVLGASSAFLWTQQLRLMQSSAALEQQWQTLAQQQAQFEQRIAGVETRQQ---QTEPPKP 81 + L F + +++ ++ +++Q+ T Q+ Q E + + Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 82 LVSAVTQEQLT--QALAENRQEVNQQHAQLQQQMTSVTQRVEVLEQRDGALSGQWLELKQ 139 +S V + +L +L + + + + + V + + + + L K+ Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 140 QMA 142 + Sbjct: 288 EYQ 290 Score = 32.5 bits (74), Expect = 0.002 Identities = 10/90 (11%), Positives = 27/90 (30%), Gaps = 15/90 (16%) Query: 37 QQLRLMQSSAALEQQWQTLAQQQAQFEQRIAGVETRQQQTEPPKPLVSAVTQEQLTQALA 96 + +++ + L ++Q EQ + +E+ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQ------IESEILS---------AKEEYQLVTQ 294 Query: 97 ENRQEVNQQHAQLQQQMTSVTQRVEVLEQR 126 + E+ + Q + +T + E+R Sbjct: 295 LFKNEILDKLRQTTDNIGLLTLELAKNEER 324
>PF01540#Adhesin lipoprotein Length = 475 Score = 31.6 bits (71), Expect = 0.007 Identities = 26/113 (23%), Positives = 55/113 (48%), Gaps = 9/113 (7%) Query: 39 QTGDSVVADLTQEELKALGVEGDTPQDTLRTLVGRMRTIQNKQVELDRDNKALAEENARL 98 +T + +A+ T+ K G GD P + L + +++Q ++D+ NK +A+EN ++ Sbjct: 66 ETLNKEIAEATKS-FKEAGSYGDYPA-IISKLSAAVENAKSEQQKVDQANKKIADENLKI 123 Query: 99 AQGESGL---DNRI---SAAVAKAQKEAEQKAEGVKEE-QRQLSKALDELKER 144 +G L +I + +A + E K + E ++QL ++ L ++ Sbjct: 124 KEGAKELLKLSEKIQSFADTIALTITKLEGKKFQIDETFKKQLISTIELLNKK 176
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.8 bits (98), Expect = 4e-06 Identities = 26/132 (19%), Positives = 57/132 (43%), Gaps = 3/132 (2%) Query: 75 AFLLSYGFSSVLLSGLGDRIAPLRLLTGMMVVWCILMVIMGFTHNYALMVTLRILLGIAE 134 AF+L++ + + L D++ RLL +++ C VI H++ ++ + + A Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 135 GPLFPLAFAVVRHTF-PQRLQARATMLWLLGTPVGAALGFPLSIWLLNTFGWQSTFFVM- 192 FP VV + P+ + +A L +G +G + + + W + Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 193 -AMLTIPVLIFV 203 ++T+P L+ + Sbjct: 177 ITIITVPFLMKL 188
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.0 bits (65), Expect = 0.016 Identities = 21/88 (23%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 28 KQMALPGYRVLAWDMPGYGESPMLAATPAD-AGDYADALARMLDRAGVEQTILVGHSLGA 86 + G+ V+ W Y P D D + + G ++ IL+G+S GA Sbjct: 72 GILQQQGWPVVGWSSLKYYWK---QKDPKDVTQDTLAIIDKYQAEFGTQKVILIGYSFGA 128 Query: 87 LVAAAFAAKYP----QRVLYLVLADVAQ 110 V + P + VL VL +Q Sbjct: 129 EVIPFVLNEMPARYRKNVLGAVLLSPSQ 156
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (272), Expect = 1e-30 Identities = 77/262 (29%), Positives = 118/262 (45%), Gaps = 9/262 (3%) Query: 1 MNAQ-IEGRVAVVTGGSSGIGFETLRLLLGEGAKVAFCGRNPDRLASAHAALQNE--YPE 57 MNA+ IEG++A +TG + GIG R L +GA +A NP++L ++L+ E + E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 58 GEVFSWRCDVLNEAEVEAFAAAVAARFGGVDMLINNAGQGYVAHFADTPREAWLHEAELK 117 ++ DV + A ++ A + G +D+L+N AG E W + Sbjct: 61 ----AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116 Query: 118 LFGVINPVKAFQSLLEASDIASITCVNSLLALQPEEHMIATSAARAALLNMTLTLSKELV 177 GV N ++ + SI V S A P M A ++++AA + T L EL Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 178 DKGIRVNSILLGMVESGQWQRRFESRSDKSQSWQQWTADIARKRGIPMARLGKPQEPAQA 237 + IR N + G E+ + + Q + K GIP+ +L KP + A A Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETF--KTGIPLKKLAKPSDIADA 234 Query: 238 LLFLASPLASFTTGAALDVSGG 259 +LFL S A T L V GG Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.010 Identities = 33/188 (17%), Positives = 73/188 (38%), Gaps = 12/188 (6%) Query: 33 SFYGIRPLLILFMAATVYDGGMGLARENASAIVGIFAGSMYLAALPGGWLADNWLGQQRA 92 SF+ + ++L ++ + + + F + + G L+D LG +R Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ-LGIKRL 81 Query: 93 VWYGSILIALGHLSIALSAWLGNDLFFIGLMFIVL---GSGLFKTCISVMVGTLYKKGDA 149 + +G I+ G ++ ++G+ F + +M + G+ F + V+V K Sbjct: 82 LLFGIIINCFG----SVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK--E 135 Query: 150 RRDGGFSLFYMGINIGSFIAPLISGWLIKSHGWHWGFGIGGIGMLVALIIFRVFAVPSMK 209 R F L + +G + P I G + +H HW + + + + + F + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGG--MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEV 193 Query: 210 RYDAEVGL 217 R + Sbjct: 194 RIKGHFDI 201
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.0 bits (67), Expect = 0.033 Identities = 33/148 (22%), Positives = 50/148 (33%), Gaps = 30/148 (20%) Query: 489 DSEAPQLKTRLAALYRRLADCLAAPKEAVPLAPLLVAFTDSEALIHRVRAEPLGTYAHPW 548 + + ++LAAL + + + K L A ++EA + E L Sbjct: 399 EKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEA---KALKEKL------- 448 Query: 549 PQAKDWPMRATLAQAEEIARLSEGYRLNAAPGDPTLAR-------CAEQLRRYAERIEQE 601 AK QAEE+A+L G ++ D A Q + + Sbjct: 449 --AK---------QAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAP 497 Query: 602 ATAPGEQL--TAELTNPFGPALAAALAA 627 QL T E NPF A A + A Sbjct: 498 MKETKRQLPSTGETANPFFTAAALTVMA 525
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 66.8 bits (163), Expect = 2e-14 Identities = 50/362 (13%), Positives = 106/362 (29%), Gaps = 81/362 (22%) Query: 11 KKWPLLALVLAAILALILVIWQL-----QTSPETNDAYVYADTIDVVPEVSGRIVEMPIR 65 + P L +I I + + + ++ P + + E+ ++ Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 66 DNQRVRKGDLLFRIDPRP---------------------YQAMLDDA------------- 91 + + VRKGD+L ++ YQ + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 ------------------KARLTTLDAQIMLTQRTIKAQEYNAQSVAAAVERARALVKQT 133 K + +T Q + + + +V A + R L + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 134 TSTRIRLEPLVPQGFASQEDLDQARTAEKAARAELEATLLQAKQASAAVTGVDAMVAQRA 193 S L+ + ++ + + A EL Q +Q + + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 194 GVL-------------------AQIALAELHLEFTEVRAPFNGVVVALKT-TVGQYASAL 233 + ++A E + + +RAP + V LK T G + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 KPVFTLL-DDDRWYVIANFRETDLNNVRPGVAARITVMT-NHNRT--FNGVVDSVGSGVL 289 + + ++ +DD V A + D+ + G A I V + R G V ++ + Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413 Query: 290 PE 291 + Sbjct: 414 ED 415
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.002 Identities = 11/55 (20%), Positives = 23/55 (41%) Query: 11 YVNDAQGNQVAEIVFVPTGEHLSIIEHTDVDPSLKGQGVGKQLVAKVVEKMRQEQ 65 ++ + N + I ++IE V + +GVG L+ K +E ++ Sbjct: 68 FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 976 bits (2525), Expect = 0.0 Identities = 665/866 (76%), Positives = 758/866 (87%), Gaps = 6/866 (0%) Query: 11 LGCRTARRLVSPALALWLC------SQPFAARADLYFNPRFLADDPAAVADLSGFEKGQE 64 C R+ + L +Q + A+LYFNPRFLADDP AVADLS FE GQE Sbjct: 13 TQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQE 72 Query: 65 VPPGTYRVDIYLNNGFMTTRDVTFQADAQGHGLSPCLTRGQLASMGVDTGRVPGMATLDS 124 +PPGTYRVDIYLNNG+M TRDVTF G+ PCLTR QLASMG++T V GM L Sbjct: 73 LPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLAD 132 Query: 125 TACVPLTTLISEATTRFDVGQQRLYLTVPQAFMGNHARGYIPPELWDNGITAGLINYNFT 184 ACVPLT++I +AT + DVGQQRL LT+PQAFM N ARGYIPPELWD GI AGL+NYNF+ Sbjct: 133 DACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFS 192 Query: 185 GNNAHNTTGGSSRYAYLNLQSGLNIGAWRLRDNSTWSYSSGGSTSSNENRWQHVNSWLER 244 GN+ N GG+S YAYLNLQSGLNIGAWRLRDN+TWSY+S S+S ++N+WQH+N+WLER Sbjct: 193 GNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLER 252 Query: 245 DITPLRSRLTLGDSYTNGDVFDGINFRGAQLASDDNMLPDSQKGFAPVIHGIARGTAQVS 304 DI PLRSRLTLGD YT GD+FDGINFRGAQLASDDNMLPDSQ+GFAPVIHGIARGTAQV+ Sbjct: 253 DIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVT 312 Query: 305 IRQNGYEIYQSTVPPGPFTIDDLYAAGNGGDLQVTIKEADGSRQVFSVPWSTVPVLQREG 364 I+QNGY+IY STVPPGPFTI+D+YAAGN GDLQVTIKEADGS Q+F+VP+S+VP+LQREG Sbjct: 313 IKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREG 372 Query: 365 HTRFALTAGEYRSGNSQQETPDFFQGTVMHGLPAGWTLYGGTQLADRYRAFNLGVGKNMG 424 HTR+++TAGEYRSGN+QQE P FFQ T++HGLPAGWT+YGGTQLADRYRAFN G+GKNMG Sbjct: 373 HTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMG 432 Query: 425 YFGALSLDITQANATLADDSEHQGQSVRFLYNKSLDETGTNLQLVGYRYSTRGYYNFADT 484 GALS+D+TQAN+TL DDS+H GQSVRFLYNKSL+E+GTN+QLVGYRYST GY+NFADT Sbjct: 433 ALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADT 492 Query: 485 TYRRMSGYSVETQDGVIQVKPKFTDYYNLAYSKRGKVQLSVTQQLGRTATLYLSGSHQTY 544 TY RM+GY++ETQDGVIQVKPKFTDYYNLAY+KRGK+QL+VTQQLGRT+TLYLSGSHQTY Sbjct: 493 TYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTY 552 Query: 545 WGTDDADEQLQAGLNAAVDDINWSLSYSLTKNAWQQGRDQMLAININIPFSHWLRSDSRS 604 WGT + DEQ QAGLN A +DINW+LSYSLTKNAWQ+GRDQMLA+N+NIPFSHWLRSDS+S Sbjct: 553 WGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKS 612 Query: 605 VWRHASASYSLSHDLNGRMTNLAGLYGTLLEDNNLSYSMQTGYAGGGNGDNGSTGYTALN 664 WRHASASYS+SHDLNGRMTNLAG+YGTLLEDNNLSYS+QTGYAGGG+G++GSTGY LN Sbjct: 613 QWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLN 672 Query: 665 YRGGYGNANVGYSRSDGFKQLYYGVSGGVLAHANGITLSQPLNDTVVLVKAPGAGGVKVE 724 YRGGYGNAN+GYS SD KQLYYGVSGGVLAHANG+TL QPLNDTVVLVKAPGA KVE Sbjct: 673 YRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVE 732 Query: 725 NQTGVRTDWRGYAVLPYATEYRENRIALDTNTLADNVDLDDAVVSVVPTHGAIVRANFNA 784 NQTGVRTDWRGYAVLPYATEYRENR+ALDTNTLADNVDLD+AV +VVPT GAIVRA F A Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 785 QVGMKILMTLTHRGKPVPFGALATGDSNQSGSIVADNGQVYLSGMPLAGKVRVKWGDGPD 844 +VG+K+LMTLTH KP+PFGA+ T +S+QS IVADNGQVYLSGMPLAGKV+VKWG+ + Sbjct: 793 RVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 845 AQCVADYRLPPESQQQALSQLSVACR 870 A CVA+Y+LPPESQQQ L+QLS CR Sbjct: 853 AHCVANYQLPPESQQQLLTQLSAECR 878
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 664 bits (1715), Expect = 0.0 Identities = 263/846 (31%), Positives = 403/846 (47%), Gaps = 47/846 (5%) Query: 10 RLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVG-SREKVDLSRFSTS-AITEGTYSL 67 + L F++ FN F+ + DLSRF + GTY + Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRV 80 Query: 68 DVYTNDEWKGRYDLR-IARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGYCGSLKS 126 D+Y N+ + D+ D + + C T+A LA G+ ++ + C L S Sbjct: 81 DIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTS 140 Query: 127 WRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNYVSPEFWDKGITALNLGWMANAWNSHT 186 + L RLN+++PQ + R + Y+ PE WD GI A L + + + Sbjct: 141 MI--HDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSG--NSV 196 Query: 187 SSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQG----KAHWNSNQTYLQRPIPQ 242 + G ++ AYL + +GL+ W L+ ++ K W T+L+R I Sbjct: 197 QNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIP 256 Query: 243 LNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVRQG 302 L S ++ G +T G+ FD I RG L++DDNM PD R +AP I G+A+ A VT++Q Sbjct: 257 LRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQN 316 Query: 303 SNIIYQTTVPPGPFTLQDVYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMTRY 362 IY +TVPPGPFT+ D+Y +G DL+V++KEADGS ++F+VPY+SV L R G TRY Sbjct: 317 GYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRY 376 Query: 363 ALSAGKV-DDSALRNKPMLYQATWQHGINNLLTGYTGVTGFDDYQAFLVGTGMNTG-IGA 420 +++AG+ +A + KP +Q+T HG+ T Y G D Y+AF G G N G +GA Sbjct: 377 SITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGA 436 Query: 421 LSFDVTHSRLKS-DAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYA- 478 LS D+T + D GQS R +N+ ++ T+I L YRYST GY+N D Y+ Sbjct: 437 LSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSR 496 Query: 479 -------------VDQEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNR 525 + K + + ++ + TV Q L YLSG YW Sbjct: 497 MNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGT 555 Query: 526 SGTEKQYQVSYNNSFGRLSWSASAQRVYTPDSSGHRRDDRISLNFSYPL--WFGDN---- 579 S ++Q+Q N +F ++W+ S T ++ RD ++LN + P W + Sbjct: 556 SNVDEQFQAGLNTAFEDINWTLSYSL--TKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQ 613 Query: 580 -RTANLTSNTSFNNSRFASSQIGINGSLDSENNLNYGVSTTTATGGQHD----VALNGSY 634 R A+ + + S + + ++ G+ G+L +NNL+Y V T A GG + +Y Sbjct: 614 WRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNY 673 Query: 635 RTPWTTLNGSYSQGEGYRQSGIGASGTMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPG 694 R + N YS + +Q G SG ++AH+ GV L T+ L++A A A + Sbjct: 674 RGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVEN 733 Query: 695 SPGTRVDSNGYAILPYLRPYRINAVEIDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTK 754 G R D GYA+LPY YR N V +D D+V D VA VVP G++V+ F + Sbjct: 734 QTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKAR 793 Query: 755 VQNNLTLQARQANHEPLPFAASIFSPDGKEIGVVGQGSMMFISDANAK-RAIVKW---SG 810 V L + N +PLPF A + S + G+V +++S + VKW Sbjct: 794 VGIKLLMTLTHNN-KPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 811 GQCSVD 816 C + Sbjct: 853 AHCVAN 858
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 593 bits (1530), Expect = 0.0 Identities = 185/571 (32%), Positives = 314/571 (54%), Gaps = 7/571 (1%) Query: 168 QTRIRALPASSGVAIAEGWMDVSLPLMEQVYEASTLDTASERERLTGALEEAANEFRRYS 227 +I + ASSGVAIA+ ++ + + + + S D ++E E+LT ALE++ E R Sbjct: 2 HHKITGIAASSGVAIAKAFIHLEPNV--DIEKTSITDVSTEIEKLTAALEKSKEELRAIK 59 Query: 228 KRYAAGAQKETAAIFDLYSHLLSDARLRRELFAEVDKGAV-AEWAVKKIIEKFAEQFAAL 286 + A + A IF + +L D L + +++ + AE+A+K++ + F F ++ Sbjct: 60 DQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESM 119 Query: 287 SDGYLKERAGDLRTLGQRLLFHLDDS-IQGPNTWPARIILVADELSATTLAEVPQDRLAG 345 + Y+KERA D+R + +R+L HL T +++A++L+ + A++ + + G Sbjct: 120 DNEYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKG 179 Query: 346 VVVRDGAANSHAAIMVRALGIPTVMGA-DIQPSLLHGHTLIVDGYRGELLVDPEPVLLQE 404 G SH+AIM R+L IP V+G ++ + HG +IVDG G ++V+P ++ Sbjct: 180 FATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKA 239 Query: 405 YQRLISEENELSRLAEDDLQRASELKSGERVKVMLNAGLSPEHEEKLGSFVDGIGLYRTE 464 Y+ + + + + S K G V++ N G + + L + +GIGLYRTE Sbjct: 240 YEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTE 299 Query: 465 IPFMLQSGFPSEEEQVAQYQGMLQMFNSKPVTLRTLDIGADKQLPYMPISEE-NPCLGWR 523 +M + P+EEEQ Y+ ++Q + KPV +RTLDIG DK+L Y+ + +E NP LG+R Sbjct: 300 FLYMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFR 359 Query: 524 GIRITLDQPEIFLIQVRAMLRANAATGNLSILLPMVTSLEEVDEARRLIDRASREVEEMI 583 IR+ L++ +IF Q+RA+LRA + GNL ++ PM+ +LEE+ +A+ ++ ++ Sbjct: 360 AIRLCLEKQDIFRTQLRALLRA-STYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEG 418 Query: 584 GYAIPRPRLGVMLEVPSMVFMLPQLASRIDFISVGTNDLTQYLLAVDRNNTRVASMYDSL 643 +G+M+E+PS A +DF S+GTNDL QY +A DR N RV+ +Y Sbjct: 419 VDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPY 478 Query: 644 HPAVLRALAMIAHDAERFGIDLRLCGEMAGDPMCVTILIGLGYRHLSMNGRSVARVKYLL 703 HPA+LR + M+ A G + +CGEMAGD + + +L+GLG SM+ S+ + L Sbjct: 479 HPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQL 538 Query: 704 RRIDIEEAQELSRRSLDAQMTAEVRHQVAAF 734 ++ EE + ++++L EV V Sbjct: 539 LKLSKEELKPFAQKALMLDTAEEVEQLVKKT 569
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 28.8 bits (64), Expect = 0.008 Identities = 19/96 (19%), Positives = 36/96 (37%), Gaps = 1/96 (1%) Query: 31 REHGYTLMETLVTLTLMMILSVGGLYGWQRWQQQQRLWQTAVQVRDFLLFLRDDANAYNR 90 R+ G+TL+E ++ L LM + + L + + A + L F++ + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLA-RFEAQLRFVQQRGLQTGQ 60 Query: 91 DRVLRVGQDEVGWCLSAEGEGPDCASGTSFTLRPRW 126 + V D + + +G D A RW Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRW 96
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 25.7 bits (56), Expect = 0.035 Identities = 10/23 (43%), Positives = 15/23 (65%) Query: 7 RQRGFSLPETVLAMALMVLTVTA 29 RQRGF+L E +L + LM ++ Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGM 24
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 559 bits (1441), Expect = 0.0 Identities = 198/395 (50%), Positives = 270/395 (68%), Gaps = 5/395 (1%) Query: 4 KIMAINAGSSSLKFQLLNMPQGALLCQGLIERIGLPEARFTLKTSAQKWQETLPIADHHE 63 KI+ IN GSSSLK+QL+ G +L +GL ERIG+ ++ T + +K + + DH + Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 64 AVTLLLEALTGR--GILSSLQEIDGVGHRVAHGGERFKDAALVCDDTLREIERLAELAPL 121 A+ L+L+AL G++ + EID VGHRV HGGE F + L+ DD L+ I ELAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 122 HNPVNALGIRLFRQLLPAVPAVAVFDTAFHQTLAPEAWLYPLPWRYYAELGIRRYGFHGT 181 HNP N GI+ Q++P VP VAVFDTAFHQT+ A+LYP+P+ YY + IR+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 182 SHHYVSSALAEKLGVPLSALRVVSCHLGNGCSVCAIKGGQSVNTSMGFTPQSGVMMGTRS 241 SH YVS AE L P+ +L++++CHLGNG S+ A+K G+S++TSMGFTP G+ MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 242 GDIDPSILPWLVEKEGKSAQQLSQLLNNESGLLGVSGVSSDYRDVEQAADA-GNERAALA 300 G IDPSI+ +L+EKE SA+++ +LN +SG+ G+SG+SSD+RD+E AA G++RA LA Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLA 301 Query: 301 LSLFAERIRATIGSYIMQMGGLDALIFTGGIGENSARARAAICRNLHFLGLALDDEKNQR 360 L++FA R++ TIGSY MGG+D ++FT GIGEN R I L FLG LD EKN+ Sbjct: 302 LNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKV 361 Query: 361 SA--TFIQADNALVKVAVINTNEELMIARDVMRLA 393 I ++ V V V+ TNEE MIA+D ++ Sbjct: 362 RGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.007 Identities = 9/58 (15%), Positives = 17/58 (29%), Gaps = 1/58 (1%) Query: 152 ADFVICFYNPRSRGREGHLARAFTLLAASKSADTPVGVVKSAGRKKQEKWLTTLGEMD 209 D+ + G+ + L S + +G K + + L EM Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFD-IGTGKDSYEQIAGIVAYELSEMT 651
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 379 bits (974), Expect = e-127 Identities = 141/356 (39%), Positives = 197/356 (55%), Gaps = 24/356 (6%) Query: 4 PESPSTAPALI--DPASKAFQSLLDKLAPTEATVLIVGETGTGKEVVARYLHHHSARRQQ 61 + L+ A + +L +L T+ T++I GE+GTGKE+VAR LH + RR Sbjct: 130 EDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNG 189 Query: 62 PFLAVNCGALTESLAEAELFGHEKGAFTGAQQGQPGWFEAAEGGTLLLDEIGELSLPLQV 121 PF+A+N A+ L E+ELFGHEKGAFTGAQ G FE AEGGTL LDEIG++ + Q Sbjct: 190 PFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQT 249 Query: 122 KLLRVLQEREITRVGSRKAIKVNVRVIAATHVDLAQAIRERRFREDLYYRLNIAVVPLPP 181 +LLRVLQ+ E T VG R I+ +VR++AAT+ DL Q+I + FREDLYYRLN+ + LPP Sbjct: 250 RLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPP 309 Query: 182 LRQRRQDIPLLAHHFLSLYARRLGRPTLRLAPESLARLMDYSWPGNIRELENTLHNAVLL 241 LR R +DIP L HF+ + G R E+L + + WPGN+RELEN + L Sbjct: 310 LRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTAL 368 Query: 242 SKEEEISPAQLRLATLNDAP-----------------GPASDHELDDFIRHQLALPGEPL 284 ++ I+ + ++ P ++ F ALP L Sbjct: 369 YPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGL 428 Query: 285 WQRVTSA----LIRHAMAHCDDNQSQAAELLGISRHTLRTQLANLGLIKSRRRPPA 336 + RV + LI A+ NQ +AA+LLG++R+TLR ++ LG+ R A Sbjct: 429 YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSSRSA 484
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.049 Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 15 GKRQIIDNVSVALRGG----EMTALIGPNGAGKSTLLRLLTG 52 GK ++ +V+ + G L G G GKSTL+ L G Sbjct: 577 GKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVG 618
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 36.8 bits (85), Expect = 5e-05 Identities = 44/191 (23%), Positives = 75/191 (39%), Gaps = 16/191 (8%) Query: 52 PPAAQKLPDVGYLRQLNAEGILALRPQLVLASAQAQPSLVLHKVQASGVKVVNVPGGESL 111 PP + DVG + N E + ++P ++ SA PS + A G G + L Sbjct: 72 PPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPL 131 Query: 112 SAIDNKVAVIAEALGKTAAGDALRQQLQQQIAAIPTQPV---AKRVLFILSHGGMNTLVA 168 + + +A+ L +A + Q + I ++ + V A+ +L + LV Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 169 GQHTAADSAIRAAGLQNAMQG---FDHYRAMSQEGVAA-SQADLVVISADGLKGMGGEAG 224 G ++ + G+ NA QG F A+S + +AA D++ D K M Sbjct: 192 GPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDM----- 246 Query: 225 LWKLPGLAQTP 235 L TP Sbjct: 247 ----DALMATP 253
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 378 bits (971), Expect = e-126 Identities = 137/373 (36%), Positives = 201/373 (53%), Gaps = 41/373 (10%) Query: 345 YREIQRLKERLVDENLALTEQLNNVESEFGEIIGRSEAMNNVLKQVEMVAQSDSTVLILG 404 E+ + R + E +L + + ++GRS AM + + + + Q+D T++I G Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 405 ETGTGKELIARAIHNLSGRNGRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRF 464 E+GTGKEL+ARA+H+ R V +N AA+P L+ES+LFGHE+GAFTGA + GRF Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227 Query: 465 ELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKLIQTDVRLIAATNRDLKQMV 524 E A+ +LFLDE+GDMP++ Q +LLRVLQ+ E+ +G I++DVR++AATN+DLKQ + Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287 Query: 525 IDREFRSDLYYRLNVFPIHLPPLRERPDDIPLLVKAFTFKIARRMGRNIDSIPAETLRTL 584 FR DLYYRLNV P+ LPPLR+R +DIP LV+ F + A + G ++ E L + Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELM 346 Query: 585 TRMEWPGNVRELENVIERAVLLTRGNVLQ------------------------------- 613 WPGNVRELEN++ R L +V+ Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406 Query: 614 -----LSLPERDIVEAPRTPAVLPEEGED-EYQLIVRVLKESNGVVAGPKGAAQRLGLKR 667 + +A + + EY LI+ L + G AA LGL R Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQI---KAADLLGLNR 463 Query: 668 TTLLSRMKRLGIN 680 TL +++ LG++ Sbjct: 464 NTLRKKIRELGVS 476
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.4 bits (216), Expect = 1e-22 Identities = 68/256 (26%), Positives = 122/256 (47%), Gaps = 5/256 (1%) Query: 3 QVAVVIGGGQTLGEFLCRGLAAEGYRVAVVDIQSEKASRVAQEINAEYGEGMAYGFGADA 62 ++A + G Q +GE + R LA++G +A VD EK +V + AE A F AD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAFPADV 66 Query: 63 TSEASVTALAHGVDEIFSRVDLLVYSAGIAKAAFISDFALGDFDRSLQVNLVGYFLCARE 122 A++ + ++ +D+LV AG+ + I + +++ + VN G F +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 FSRLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 182 S+ M D G I+ + S V + Y+++K V T+ L L+LAEY I + + Sbjct: 127 VSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 MLGNLLKSPMFQSLLPQYATKLGIDESEVEQYYIDKVPLKRGCEYQDVLNVLMFYASPQA 242 G+ ++ M SL + + +E + +PLK+ + D+ + ++F S QA Sbjct: 186 SPGST-ETDMQWSLWADENGAEQVIKGSLETFKTG-IPLKKLAKPSDIADAVLFLVSGQA 243 Query: 243 SYCTGQSINVTGGQVM 258 + T ++ V GG + Sbjct: 244 GHITMHNLCVDGGATL 259
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.038 Identities = 14/74 (18%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 19 ALVVCLALSLSTTMLGVFLLLRRMSLMGDALSHAILP-GVAVGYLLSGMSLLAMTLGG-- 75 + + +ALS L + LM + LP A+ Y++ + L L Sbjct: 31 STALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFPL 90 Query: 76 FIAGIVVALVAGWV 89 ++A+ + V Sbjct: 91 LTVAALMAIASHVV 104
>adhesinb#Adhesin B signature. Length = 310 Score = 236 bits (604), Expect = 4e-79 Identities = 92/308 (29%), Positives = 169/308 (54%), Gaps = 17/308 (5%) Query: 1 MKRSAIVVALALGLMAQGAMAKT----------LNVVSSFSVLGDIAQQVGGEHVHVDTL 50 MK+ +V L L + A + LNVV++ S++ DI + + G+ +++ ++ Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSI 60 Query: 51 VGPDGDPHTFEPSPKDSALLSKADVVVVNGLGLE----GWLDRLIKASGFKGE--LVVAS 104 V DPH +EP P+D S+AD++ NG+ LE W +L++ + K S Sbjct: 61 VPVGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVS 120 Query: 105 KGVKTHTLDEEGKTVT-DPHAWNSAANGALYAQNILDGLVKADPEDKAALTSSGKRYIDQ 163 +GV L+ + + DPHAW + NG +YAQNI L + DP +K + K Y+++ Sbjct: 121 EGVDVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEK 180 Query: 164 LTSLDGWAKAQFSAIPLAKRKVLTSHDAFGYFGRAYHVTFLAPQGLSSESEASTAQVAAL 223 L++LD AK +F+ IP K+ ++TS F YF +AY+V +++E E + Q+ L Sbjct: 181 LSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTL 240 Query: 224 IKQIKADGVHTWFMENQLDPRLVKQIASATGAQPGGELYPEALSKPGGVADSYVKMMRHN 283 +++++ V + F+E+ +D R +K ++ T +++ +++++ G DSY MM++N Sbjct: 241 VEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYN 300 Query: 284 VELIAKSM 291 +E IA+ + Sbjct: 301 LEKIAEGL 308
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 287 bits (737), Expect = 1e-92 Identities = 122/366 (33%), Positives = 173/366 (47%), Gaps = 52/366 (14%) Query: 268 LTTPQGRYHYRLREPTRRRVAVSAPPAMHLPFTSPREGEKLLRLLNAGIALCIEGETGSG 327 L P+ R + V AM + L RL+ + L I GE+G+G Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY------RVLARLMQTDLTLMITGESGTG 172 Query: 328 KEYVSRTLHRHSRWRSGKFVAINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREAD 387 KE V+R LH + + R+G FVAIN AAIP LIESELFG++ GAFTGA G+ +A+ Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRS-TGRFEQAE 231 Query: 388 GGVLFLDEIGDMPLALQTRLLRVLQEKEVAPLGASRSVPVNFALICATHRNLTQRVSAGE 447 GG LFLDEIGDMP+ QTRLLRVLQ+ E +G + + ++ AT+++L Q ++ G Sbjct: 232 GGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGL 291 Query: 448 FREDLLWRLREYALALPPLREW----PALETFIATLWHDLGGASRRVTLSNALLVHLSQL 503 FREDL +RL L LPPLR+ P L G +R L + Sbjct: 292 FREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKR--FDQEALELMKAH 349 Query: 504 PWPGNVRQLQSVLKVMLALADEGDTLTPDALPEAYRAAPAPLPRGG-------------- 549 PWPGNVR+L+++++ + AL D +T + + R+ P Sbjct: 350 PWPGNVRELENLVRRLTALY-PQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAV 408 Query: 550 ------------------------LQAHDEQLIVDTLARVNGNVSRAAQILGIARSTLYR 585 L + LI+ L GN +AA +LG+ R+TL + Sbjct: 409 EENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRK 468 Query: 586 RAARAG 591 + G Sbjct: 469 KIRELG 474
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 27.6 bits (61), Expect = 0.017 Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 8/78 (10%) Query: 36 GSRVLELGPTQMTAAVDVSKAGISKTFTTRNTLTSNQSILMSLVDGPFKKLIGGWK---- 91 G+ VLE+ P+ + +D G + + LT I S+++G +++ + Sbjct: 113 GNAVLEVDPSITFSIIDRLFGGTGQAAKVQRDLT---DIENSVMEGVIVRILANVRESWT 169 Query: 92 -FIPLSPEACKIEFHLDF 108 I L P +IE + F Sbjct: 170 QVIDLRPRLGQIETNPQF 187
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 28.8 bits (64), Expect = 0.028 Identities = 13/46 (28%), Positives = 21/46 (45%), Gaps = 5/46 (10%) Query: 236 DPKPQKQKVTLKRKPKEQHLRALQHPKAKPVTKKKTVKEPEAREGE 281 P+P K+ + KPK + PK KPV K + + + + E Sbjct: 78 IPEPPKEAPVVIEKPKPK-----PKPKPKPVKKVQEQPKRDVKPVE 118
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.018 Identities = 30/175 (17%), Positives = 57/175 (32%), Gaps = 5/175 (2%) Query: 6 KLQVLLKAVDQATRPFKSIQTASKTLSGDIRDTQKSLRELNGQAS-RIDGFRKASAQLAV 64 A + ++ + A D+ + + S +I A L Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 260 Query: 65 TGQELKKAKQEAAALAIQFRNTEQPTRAQAQAMDA----ARKSAAALQLKHNSLRQAVQR 120 EL+KA + A + + A+ A++A + L SLR+ + Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320 Query: 121 QRQELSQAGINTRSLAADERRLKTSISETTAQLNRQREALARVSAQQAKLNAVKQ 175 R+ Q + L + + S L+ REA ++ A+ KL + Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 32.0 bits (72), Expect = 7e-04 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 7/48 (14%) Query: 105 SISLLLTERTLVKEADGAMY--VENIPEPPPPEPV-----TRPVEMWS 145 ++ L RTL E DG V N+ PPPP P+ +RP W+ Sbjct: 340 ILTQLCAARTLAYEGDGYRRAPVNNMMPPPPPPPMMGGNSSRPKSKWA 387
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1286 bits (3330), Expect = 0.0 Identities = 657/1032 (63%), Positives = 801/1032 (77%), Gaps = 2/1032 (0%) Query: 1 MANFFIDRPIFAWVLAILLCLTGALAILSLPVEQYPDLAPPNVRITANYPGASAQTLENT 60 MANFFI RPIFAWVLAI+L + GALAIL LPV QYP +APP V ++ANYPGA AQT+++T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMTGLDNLMYMSSQSSATGQATITLSFTAGTDPDEAVQQVQNQLQSAMRKLPQ 120 VTQVIEQNM G+DNLMYMSS S + G TITL+F +GTDPD A QVQN+LQ A LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQNQGVTVRKTGDTNILTLAFVSTDGSMDKQDIADYVASNIQDPLSRVNGVGDIDAYGS 180 VQ QG++V K+ + ++ FVS + + DI+DYVASN++D LSR+NGVGD+ +G+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYSMRIWLDPAKLNSYQMTTKDVTDAISSQNAQIAVGQLGGTPSVDKQALNATINSQSLL 240 QY+MRIWLD LN Y++T DV + + QN QIA GQLGGTP++ Q LNA+I +Q+ Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTPEQFRNITLRVNQDGSEVTLGDVATVEMGAEKYDYLSRYNRQPASGLGIKLASGANEM 300 + PE+F +TLRVN DGS V L DVA VE+G E Y+ ++R N +PA+GLGIKLA+GAN + Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 ATAERVINRLNELAQFFPHGLEYKVAYETTSFVKASITDVVKTLLEAILLVFLVMYLFLQ 360 TA+ + +L EL FFP G++ Y+TT FV+ SI +VVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLMGTFAVLYACGYSINTLTMFAMVLAIGLLVDDAIVVVENVERIM 420 N RATLIPTIAVPVVL+GTFA+L A GYSINTLTMF MVLAIGLLVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480 E+ L P+EAT KSM QIQGALVGIAMVLSAVF+PMAFFGG+TGAIYRQFSITIV+AM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVAMILTPALCATLLKPVKPGESHERTGFFGWFNRTFNRSASRYETFVGKILHRSLRW 540 SVLVA+ILTPALCATLLKPV + GFFGWFN TF+ S + Y VGKIL + R+ Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 MLIYVLLLGGMVFLFLHLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVQKAEDYFLNN 600 +LIY L++ GMV LFL LP+SFLP ED+G+F T +QLP+G+TQ++T KV+ + DY+L N Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKQNVESVFATVGSGPGGNGQNVARMFVRLKDWDQRDPQTGTSFAIIERATKAFNQINEA 660 EK NVESVF G G QN FV LK W++R+ ++ A+I RA +I + Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 RVIASSPPAISGLGSSAGFDMELEDHAGKGHDALMAARDTLLELAGKNPL-LTRVRHNGL 719 VI + PAI LG++ GFD EL D AG GHDAL AR+ LL +A ++P L VR NGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 DDSPQLQVDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAKYRM 779 +D+ Q ++++DQ KAQALGVS+ DIN T+ TA G +YVNDF+DRGRVKK+YVQA AK+RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 780 LPDDINLWYVRNSSGTMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGISTGTAM 839 LP+D++ YVR+++G MVPFSAF TS W GSPRLERYNG ++EI GEAAPG S+G AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 840 DMMEKLAAQLPTGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSV 899 +ME LA++LP G G +WT MSYQERLSG QAPAL AIS +VVFLCLAALYESWS+P SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 900 MLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANELNEK-GQDLL 958 MLVVPLG++G LLA + +NDVYF VGLLT IGLSAKNAILIVEFA +L EK G+ ++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 959 SATLSACRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATVLAIFF 1018 ATL A R RLRPILMTSLAFI GVLP+A S GAGSG+Q+AVG GVMGGM+SAT+LAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1019 VPLFFVLVRRRF 1030 VP+FFV++RR F Sbjct: 1021 VPVFFVVIRRCF 1032
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 43.2 bits (102), Expect = 5e-07 Identities = 47/179 (26%), Positives = 69/179 (38%), Gaps = 41/179 (22%) Query: 33 LGIDLGTCD----------------VVSMVVDRDGQPVAVCL--DWADVVL--------- 65 L IDLGT + VV++ DR G P +V A +L Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPGNIAA 72 Query: 66 -----DGIVWDFFGAVTLVRRHLATLEQQLGCRFT-HAATSFPPGTDP---RISINVLES 116 DG++ DFF +++ + + R + P G R + Sbjct: 73 IRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQG 132 Query: 117 AGLEISHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKQGRVTYSADEATGG 170 AG +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 133 AGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 6e-11 Identities = 23/142 (16%), Positives = 58/142 (40%), Gaps = 9/142 (6%) Query: 7 KVIIVEDEFLAQQELSWLINTHSQMEIVGSFDDGLDVLKFLQHNKVDAIFLDINIPSLDG 66 +++ +D+ + L+ ++ V + + +++ D + D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALS--RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 67 V-LLAQNISQFAHKPFIVFITAWK--EHAVEAFELEAFDYILKPYQESRIINMLQKLTTA 123 LL + P +V ++A A++A E A+DY+ KP+ + +I ++ + A Sbjct: 63 FDLLPRIKKARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---A 118 Query: 124 WQQQNNAASGLASAAPRENDTI 145 + S L + + Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLV 140
>PF06580#Sensor histidine kinase Length = 349 Score = 217 bits (555), Expect = 4e-68 Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 11/207 (5%) Query: 342 RAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIE 401 ++ MA +A+L AL+++INPHF+FNALN I + I +P AR+++ +LS +RY++ Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 402 LKDDEQIDIKRELYQIKDYIAIEQARFGDKLTVIYDIDDDV-SCVIPSLLIQPLVENAIV 460 + Q+ + EL + Y+ + +F D+L I+ + +P +L+Q LVEN I Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIK 269 Query: 461 HGIQPCKGKGVVTIGINECGNRVRISVRDTGNGIDPAVVARVEADEMPGNKIGLLNVHHR 520 HGI G + + + V + V +TG+ + GL NV R Sbjct: 270 HGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK--------NTKESTGTGLQNVRER 321 Query: 521 VKLLYGE--GLHIRNLTPGTEIAFYVP 545 +++LYG + + +P Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.001 Identities = 73/361 (20%), Positives = 117/361 (32%), Gaps = 19/361 (5%) Query: 31 LLPDIRAASGMSYTLAALLTALPVIAMGVLALAAGWVDRYIGQKRSIALSLLIIAAGALL 90 LL D+ ++ ++ LL ++ + DR+ G++ + +SL A + Sbjct: 31 LLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF-GRRPVLLVSLAGAAVDYAI 89 Query: 91 REIAPNSGLLLTSALAGGIGIGIIQAAIPAVIKHLFPRRT-PLVMGLWSAALMGGGGLGA 149 AP +L + GI G A A I + G SA G G Sbjct: 90 MATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGP 148 Query: 150 AFTPWLA--SHSAAWHDALAWWALPALLALL----SWLAICRHLPRAPHQTSASSRVAII 203 + S A + A A L L S R L R AS R A Sbjct: 149 VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARG 208 Query: 204 GQRRAWTLGLYFG--LINAGYASLIAWLPPYYIQLGDSAQYSGSLLALLTVGQTAGALLL 261 A + ++F L+ A+L D+ SL A + A A++ Sbjct: 209 MTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHW-DATTIGISLAAFGILHSLAQAMIT 267 Query: 262 PALARQEDRRQLLLLALALQLIGFCGFIWLPEHFSALWAIACGVGLGGAFPLC---LVLA 318 +A + R+ L+L + G+ + + A + G P L Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQ 327 Query: 319 LDHAGQPAVAGRLVAFMQGIGFIIAGLSPWLSGLLRSLSGNYTLDWSWHAICVLLLMALT 378 +D Q + G L A + P L + + S W+W A L L+ L Sbjct: 328 VDEERQGQLQGSLAALTSLTSIV----GPLLFTAIYAASITTWNGWAWIAGAALYLLCLP 383 Query: 379 L 379 Sbjct: 384 A 384
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.1 bits (78), Expect = 1e-04 Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 12/74 (16%) Query: 1 MMTWQDLHHSELTVPQLYALLKLRSEVFV--------VEQQCVYQDVDGDDLVGENRHLL 52 M+ D++H+ L+ + L LR E F + D ++ +L Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNN----TTYLF 56 Query: 53 GWRDGELVAYARIL 66 G +D ++ R + Sbjct: 57 GIKDNTVICSLRFI 70
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 41.3 bits (97), Expect = 3e-06 Identities = 28/171 (16%), Positives = 61/171 (35%), Gaps = 31/171 (18%) Query: 94 LLVPMVDTAEQAREVVSATRYPPIGSRGVGAGVARAARWGRVENYMAEANDELCLLIQVE 153 ++ PM+ T E+ R+ A + E + E+ +++++ Sbjct: 389 VMFPMIATLEELRQAK--------------AIMQEEKDKLLSEGVDVSDSIEVGIMVEIP 434 Query: 154 SRTALENLDAILEVDGIDGVFIGPADL----------SASLGYPDDAGHPDVQRVIEQSI 203 S + + +D IG DL + + Y HP + R+++ I Sbjct: 435 S--TAVAANLFAKE--VDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVI 490 Query: 204 RRIRAAGKAAGF---LAVDPAMAEKCLAWGANFVAVGVDTMLYTQALDRRL 251 + + GK G +A D L G + ++ ++L ++ +L Sbjct: 491 KAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKL 541
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.029 Identities = 23/119 (19%), Positives = 46/119 (38%), Gaps = 6/119 (5%) Query: 59 GFSRGDLGFALSGISIAYGFSK-FIMGSVSDRSNPRIFLPAGLILAALVMLVMGFVPWAT 117 + +G +L+ I + ++ I G V+ R R L G+I +++ F Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 118 SSIMIMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLF 176 + IM +L G+G P + ++ +G + ++ + PLLF Sbjct: 302 MAFPIMVLLASG-----GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLF 355
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 28.8 bits (64), Expect = 0.042 Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 4/54 (7%) Query: 252 NYSYDWMFKPGAMAQIAQYADGIGPDYHMLVAEGSKPGAVKLTAMVKEAHASHL 305 +Y YD+ F A+ +G Y+ L + K + + A+ A + HL Sbjct: 1143 SYGYDFAFFRNALVLKPS----VGVSYNHLGSTNFKSNSNQKVALKNGASSQHL 1192
>PF06580#Sensor histidine kinase Length = 349 Score = 211 bits (539), Expect = 1e-65 Identities = 59/216 (27%), Positives = 117/216 (54%), Gaps = 3/216 (1%) Query: 343 LGEGIAQLLSAQILAGQYERQKALLTQSEIKLLHAQVNPHFLFNALNTLKAVIRRDSDQA 402 L G + + + ++ ++++ L AQ+NPHF+FNALN ++A+I D +A Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193 Query: 403 GQLVQYLSTFFRKNLKR-PTEIVTLADEIEHVNAYLQIEKARFQANLQIQMAVPEGLAHH 461 +++ LS R +L+ V+LADE+ V++YLQ+ +F+ LQ + + + Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253 Query: 462 QLPAFTLQPIVENAIKHGTSQHLGVGEITIRASQDDRWLQLDIEDNAGL-YRANPQASGL 520 Q+P +Q +VEN IKHG +Q G+I ++ ++D+ + L++E+ L + +++G Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313 Query: 521 GMNLVDRRLRARFGADCGISVTCEPERFTRVTLRLP 556 G+ V RL+ +G + I ++ + + + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.6 bits (173), Expect = 3e-16 Identities = 36/168 (21%), Positives = 70/168 (41%), Gaps = 10/168 (5%) Query: 3 RVLIVDDEPLARENLRILLETQRDIEIVGECGNAVEAIGAVHKLRPDVLFLDIQMPRISG 62 +L+ DD+ R L L + ++ NA + D++ D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 LEMVGMLDPEHRPYI--VFLTAFD--EYAVKAFEEHAFDYLLKPIEAARLEKTLARLRQE 118 +++ + + RP + + ++A + A+KA E+ A+DYL KP + L + R E Sbjct: 63 FDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 119 RNLQDVSLLDDAQQTLKYIPCTGHSRIWLLQMEDVAFVSSRMSGIYVT 166 + L DD+Q + + G S +A + + +T Sbjct: 122 PKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMIT 166
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 1e-04 Identities = 15/85 (17%), Positives = 35/85 (41%), Gaps = 7/85 (8%) Query: 58 DEQLWVAECDGQPVGFAAV---WTADNFLHHLFVDPDWQGKHIGSALLAQVERTFTASGT 114 + ++ + +G + W + + V D++ K +G+ALL + + Sbjct: 64 GKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHF 123 Query: 115 LKCLMENKN----ALRFYQRHGWTI 135 ++E ++ A FY +H + I Sbjct: 124 CGLMLETQDINISACHFYAKHHFII 148
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 34.3 bits (79), Expect = 0.001 Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 17/105 (16%) Query: 13 QAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSRE----------DA 62 Q R D ++ +A I+D G I AD+G+ IA++ G+ + Sbjct: 60 QVTREGGAVDTVITNALILD-HWG-IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 63 HEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVF 107 EV + G ++ G MD+H+H + P++ E L G T + Sbjct: 118 TEVIAGEGKIVTAGGMDSHIHF----ICPQQ-IEEALMSGLTCML 157
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.1 bits (73), Expect = 0.002 Identities = 13/52 (25%), Positives = 22/52 (42%) Query: 92 ILVTGASGGVGSTAVVLLKALGYRVTAVSGRESTHDYLRQLGADTILPRSDF 143 LVTGA+G +G L G++V + +D + +L + F Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGF 54
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 71.2 bits (174), Expect = 6e-17 Identities = 26/167 (15%), Positives = 58/167 (34%), Gaps = 3/167 (1%) Query: 16 PPKVDRQFDDTRQALIRSGLEVLTETGYLAAGIDAVIKNIAVPKGSFYHCFKSKEAFGLA 75 K ++ +TRQ ++ L + ++ G + + + K V +G+ Y FK K Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 76 VLAAYGDFFAHKLDKFLLDDAVPPLERMAAFVRHAGQGMEKFQFRRGCLVGNLLQEAPLL 135 + ++ PL + + H + + RR L+ + + + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL-LMEIIFHKCEFV 120 Query: 136 PETFPQRLMAILAAWESR--VARCLREAQAAGAIASDASPQALAQVF 180 E + ES + + L+ A + +D + A + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 7e-04 Identities = 19/91 (20%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Query: 223 LDQLLEDYGDRLKELTKSPKELKEQLEKINTSLRQQAAQVNTTEDEFQEAAGKRRELRKK 282 L+ D + + L + + L+ L+ + +Q A+ E++ + + R+ LR+ Sbjct: 293 LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 283 LEESRERRAEVSAMLERFRLLDRHYLSDIER 313 L+ SRE + ++ A + +L +++ +S+ R Sbjct: 353 LDASREAKKQLEAEHQ--KLEEQNKISEASR 381 Score = 34.7 bits (79), Expect = 0.001 Identities = 38/276 (13%), Positives = 87/276 (31%), Gaps = 31/276 (11%) Query: 206 SNKSEPEELSRKAQLRLLDQLLEDYGDRLKELTKSPKEL----------KEQLEKINTSL 255 + K + + + L +++ R +L K+ + + LE +L Sbjct: 96 NAKEKLRKNDKS--LSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 153 Query: 256 RQQAAQVNTTEDEFQEAAGKRRELRKKLEESRER-RAEVSAMLERFRLLDRHYLSDIERL 314 + A + + + K LE + A + + + +D ++ Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213 Query: 315 RAIEEGGTLFSVLSAGHCPLCGAAPDHHPPDTGCNGDTDAVVQAARVEIAKIEVLRTELV 374 + +E + A A + + A ++ E A +E + EL Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNF-------STADSAKIKTLEAEKAALEARQAELE 266 Query: 375 ATVQSLEREGANFDRRIPTVVRE---LESISESVEEFLAPKLSTLRKSYSDFADKRAEVR 431 ++ +I T+ E LE+ +E + + D R + Sbjct: 267 KALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKK 326 Query: 432 EALALYATVQ------DMERR--RADLEKGTEDEKA 459 + A + ++ + R+ R DL+ E +K Sbjct: 327 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 362 Score = 31.2 bits (70), Expect = 0.014 Identities = 26/112 (23%), Positives = 52/112 (46%), Gaps = 10/112 (8%) Query: 197 ADDSALVATSNKSEPEELSRKAQLRLLD------QLLEDYGDRLKELT----KSPKELKE 246 A ++ ++S+ +R++ R LD + LE +L+E S + L+ Sbjct: 292 ALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 351 Query: 247 QLEKINTSLRQQAAQVNTTEDEFQEAAGKRRELRKKLEESRERRAEVSAMLE 298 L+ + +Q A+ E++ + + R+ LR+ L+ SRE + +V LE Sbjct: 352 DLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALE 403
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 55.2 bits (132), Expect = 1e-10 Identities = 60/250 (24%), Positives = 94/250 (37%), Gaps = 53/250 (21%) Query: 105 VVIPPNSRDWHTNMLVVTSKRLYNVELNVIDDKSAQQPAFQVSYRYPGE-------ERDK 157 + + P+ W TN++V T+K LY L + + V YP E + Sbjct: 268 IELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEEL 327 Query: 158 ASREATARQREW------------------------------EQKQ----------QHAS 177 RE RQRE E+KQ + Sbjct: 328 KKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQY 387 Query: 178 VQKALNSAQTPRNWNYTKYPGKGSFYIDPDFAYDDGRFTFVGFSPSKSIPSV-TKELNGK 236 V AL PRN+NY + P K S +I P +DDG FT+ GF P++ + +GK Sbjct: 388 VHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGK 447 Query: 237 EHVVNSSIQKKGNFTVL---VIQEVTPRLVLRSGYTVVGLENSGFGKVHAADGSTVSR-- 291 + +++I + L + E+ + L +V + N G+GK + Sbjct: 448 LSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYG 507 Query: 292 QVERVEKPEP 301 ++ERV K P Sbjct: 508 ELERVIKKLP 517 Score = 33.2 bits (75), Expect = 0.001 Identities = 30/173 (17%), Positives = 73/173 (42%), Gaps = 24/173 (13%) Query: 38 YNPQNVTVVNTKPGFM---------------TTLVFDNDEAVISARPGFDEAWEATPDAN 82 +N V VVN K ++ T + + DE + GF++ W P++N Sbjct: 34 FNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSN 93 Query: 83 RVNVRPVALTQGAPGEDGNTTQVVIPPNSRDWHTNMLVVTSKRLYNVELNVIDDKSAQQP 142 + ++P ++ E ++ +RD+ + +K+L ++ D K ++ Sbjct: 94 HIFIQPKSVKSNLMFEKEAVNFALM---TRDYQE---FLKTKKLI---VDAPDPKELEEQ 144 Query: 143 AFQVSYRYPGEERDKASREATARQREWEQKQQHASVQKALNSAQTPRNWNYTK 195 + +E+ + +++ +R+ E+ + A+++ N+ P+N + K Sbjct: 145 KKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNK 197
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 173 bits (439), Expect = 2e-56 Identities = 51/223 (22%), Positives = 97/223 (43%), Gaps = 11/223 (4%) Query: 4 QKLIAESRTFEQQMIERDKRATKAGFVVGGVGLLIAVLALVAVVVMLPLKQTDVELYTVD 63 + E+ ++E+ + +R+ K +VV GV +A +VAV + PLK + + TVD Sbjct: 11 KAYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVD 70 Query: 64 NHTGRVEHVTR-TSKTSLTATEAYQKAMAANYVKVRERYVYPSLQDDYETVQVYNAPQVN 122 +TG + ++T EA +K A YV+ RE ++ + ++ ++ V V +A Sbjct: 71 RNTGEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQ 130 Query: 123 DDYLALYAGKN--APDKVYKNGAHTVKVEILSNQITDATAPDRVATIRYKKIIRRLADNS 180 D + Y N +P + N V VEI VA + + K ++++ Sbjct: 131 DRWSRFYKTDNPQSPQNILANRT-DVFVEIKRVSFL----GGNVAQVYFTKESVTGSNST 185 Query: 181 TRNEYWDARFTFHSDPDKEMSDAEREINYFGFTVTSWQTDREI 223 + ++ + +R N G+ V S++ D E+ Sbjct: 186 KTDAVATIKYKV---DGTPSKEVDRFKNPLGYQVESYRADVEV 225
>SECA#SecA protein signature. Length = 901 Score = 57.6 bits (139), Expect = 6e-12 Identities = 23/51 (45%), Positives = 26/51 (50%) Query: 164 ERITPAALALYQYWIANPQPVEAPQPIRNEAKVGRNDPCPCGSGKKYKQCC 214 E A + + + A E KVGRNDPCPCGSGKKYKQC Sbjct: 847 EAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCH 897
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 104 bits (262), Expect = 2e-26 Identities = 81/395 (20%), Positives = 158/395 (40%), Gaps = 20/395 (5%) Query: 25 FMEFLDGTVIATALPDMARDFGVTAVELNIGISAYLITLAVLIPASGWIADRFGARAIFT 84 F L+ V+ +LPD+A DF N +A+++T ++ G ++D+ G + + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 85 LALAIFTLASVFCGLS-TEVHIFVAMRILQGVGGALMVPVGRLAVLRTTPKHQLIKAIAT 143 + I SV + + + + R +QG G A + + V R PK KA Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 144 LTWPALVAPIIGPPLGGFITRYASWHWIFFINVPLGLAAIILSLRIIPDIRETERRSFDL 203 + + +GP +GG I Y HW + + +P+ + L + + FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 204 SGFITTSVAMVSLVTAMERLGDRQPQIWPTLALAALGFGCLLYSIRHFRRAAAPMVRLDA 263 G I SV +V + L ++ L F ++H R+ P V Sbjct: 202 KGIILMSVGIVFFMLFTTS------YSISFLIVSVLSFLIF---VKHIRKVTDPFVDPGL 252 Query: 264 LQVPTFRVTMYGGSLFRASISAVPFLLPLLFQVGFGMDPFHSGLLVLAVFVGNLTI---K 320 + F + + G + +++ ++P + + + G +++ F G +++ Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII--FPGTMSVIIFG 310 Query: 321 PATTPLIRWLGFRRLLLINGALNVCSLLACALLTPQTPVW-AIMLILYLGGVFRSIQFTG 379 L+ G +L I S L + L T + I+++ LGG+ S T Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKTV 368 Query: 380 VSTLAFADVPAAQMSDANTLFSTASQLAVGLGITL 414 +ST+ + + + +L + S L+ G GI + Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 241 bits (617), Expect = 8e-81 Identities = 67/303 (22%), Positives = 117/303 (38%), Gaps = 27/303 (8%) Query: 6 TLLCAGLGAVFLFAQVPLASAA-------VVTSMKPLGFIAAAIADGVTETQVLLPDGAS 58 TLL L A+ L A VV + + I IA + ++P G Sbjct: 6 TLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQD 65 Query: 59 EHDYSLRPSDVKRLQNADLVVWIGPEMEAFMDKSTQSIAANKKVTIAELDGVKPLLITGA 118 H+Y P DVK+ ADL+ + G +E + + N K T + ++ Sbjct: 66 PHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKT----ENKDYFAVSDG 121 Query: 119 DDDDDHHGHGHGAAEKGDGDHHHGIYNMHLWLSPEIARLSAVAIHDKLLELMPQSRAKLD 178 D G EKG D H WL+ E + A I +L P ++ + Sbjct: 122 VDVIYLEGQN----EKGKEDPH-------AWLNLENGIIFAKNIAKQLSAKDPNNKEFYE 170 Query: 179 SNLQQFETALAATDKQVSNELA--PLKGKGYFVFHDAYGYFEKHYGLTSLGHFTVNPEIQ 236 NL+++ L DK+ ++ P + K A+ YF K YG+ S + +N E + Sbjct: 171 KNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEE 230 Query: 237 PGAQRLHEIRTQLVEQKATCVFAEPQFRPAVIEAVARGTSVRMGT---LDPLGTGITLGK 293 +++ + +L + K +F E ++ V++ T++ + D + G Sbjct: 231 GTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGD 290 Query: 294 TSY 296 + Y Sbjct: 291 SYY 293
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 539 bits (1391), Expect = 0.0 Identities = 286/356 (80%), Positives = 319/356 (89%) Query: 1 MTRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLN 60 MTRP+ AS+DL AL+QNL IVR+AA +R+W+VVKANAYGHG+ R+WSA+ A DGFALLN Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN 60 Query: 61 LEEAILLREQGWKGPILLLEGFFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDI 120 LEEAI LRE+GWKGPIL+LEGFFHA +L + DQ+RLTT VHSNWQ+KALQ A+L+APLDI Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDI 120 Query: 121 YLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHFAEAENPQGIVEPMRRIEQAA 180 YLKVNSGMNRLGF P+RV TVWQQLRA++NVGEMTLMSHFAEAE+P GI M RIEQAA Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIEQAA 180 Query: 181 EGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEII 240 EGL+C RSL+NSAATLWHPEAHFDWVRPGI+LYGASPSGQW+DIANTGL+PVMTL SEII Sbjct: 181 EGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII 240 Query: 241 GVQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVS 300 GVQ L+ GE +GYGG Y EQRIGIVA GYADGYPR AP+GTPVLVDGVRT TVG VS Sbjct: 241 GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVS 300 Query: 301 MDMLAVDLTPCPQAGIGAPVELWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL 356 MDMLAVDLTPCPQAGIG PVELWGKEIKIDDVAA++GTVGYELMCALA RVPVVT+ Sbjct: 301 MDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV 356
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.2 bits (60), Expect = 0.043 Identities = 9/37 (24%), Positives = 14/37 (37%) Query: 1 MKLRWLLILVVFLAGCSSKHDYTNPPWNPEVPVKRAM 37 ++L L + L GC+S +P R M Sbjct: 3 LRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTM 39
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 502 bits (1295), Expect = 0.0 Identities = 163/395 (41%), Positives = 246/395 (62%), Gaps = 11/395 (2%) Query: 7 VLVINCGSSSIKFSVLDAASCDCLLNGVAEGINAERASLSLNGGE---PVALAQRGYEGA 63 +LVINCGSSS+K+ ++++ + L G+AE I + L+ N + + ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 64 LQAIAGALAQRDL-----IDSVALIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLH 118 ++ + AL D + + +GHRV HGG+ FT SV+I+++V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 119 NYASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLPWEYYQNLGVRRYGFHGTS 178 N A++ GI + ++ P+V VAVFDT+FHQT+ A+LY +P+EYY +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 179 HRYVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSG 238 H+YVSQRA +L P + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 239 DVDFGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLR-VLEQAWHEGHARARLAI 297 +D ++++ + + ++ + N SG+ GISG+SSD R + + A+ G RA+LA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 298 KTFVHRIARHIAGHAAALQRLDGIIFTGGIGENSVLIRRLVSERLTVFGLAMDAARNQQP 357 F +R+ + I +AAA+ +D I+FT GIGEN IR + + L G +D +N+ Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 358 NSAGERLISADGSRVRCAVIPTNEERMIALDAIRL 392 E +IS S+V V+PTNEE MIA D ++ Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKI 395
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.2 bits (104), Expect = 3e-08 Identities = 21/64 (32%), Positives = 26/64 (40%), Gaps = 2/64 (3%) Query: 73 STWLGRNGIYMEDLYVTPDYRGIGAGKALLKTIAQYAVQRQCGRLEWSVLDWNQPAIDFY 132 S W G +ED+ V DYR G G ALL ++A + L D N A FY Sbjct: 84 SNWNGY--ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFY 141 Query: 133 LSIG 136 Sbjct: 142 AKHH 145
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.001 Identities = 31/134 (23%), Positives = 53/134 (39%), Gaps = 18/134 (13%) Query: 99 LMRPIGAIVLGAYIDKVGRRKGLIVTLSIMATGTFLIVLIPSYQTIGLWAPLLVLIGRLL 158 LM+ A VLGA D+ GRR L+V+L+ A ++ P LW ++ IGR++ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIV 105 Query: 159 QGFSAGAELGGVSVYLAEIATSGRKGFYTSWQSGSQQVAIMVAAAMGFALNAVLEPSAIS 218 G + GA Y+A+I + + + S ++ +G + Sbjct: 106 AGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGF------- 157 Query: 219 DWGWRIPFLFGCLI 232 PF + Sbjct: 158 --SPHAPFFAAAAL 169
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.2 bits (81), Expect = 1e-04 Identities = 39/157 (24%), Positives = 62/157 (39%), Gaps = 20/157 (12%) Query: 48 ASDSLLVTLLVAISNFFWLPVGGALSDRFGRRSVLIAMTLLALATAWPALTMLANAPSFL 107 + ++ L A+ F PV GALSDRFGRR VL L++LA A ++A AP Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVL----LVSLAGAAVDYAIMATAPFLW 97 Query: 108 MMLSVLLWLSFIYGMYNGAMIPALT----EIMPAEVRVAGFSLAYSLATAVFGGFT--PV 161 + L++ I GA +I + R F ++ G PV Sbjct: 98 V-----LYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF---MSACFGFGMVAGPV 149 Query: 162 ISTALIEYTGDKASPGYWMSFAAICGLLATCYLYRRS 198 + + ++ +P + + L C+L S Sbjct: 150 LGGLMGGFS--PHAPFFAAAALNGLNFLTGCFLLPES 184
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.011 Identities = 14/76 (18%), Positives = 32/76 (42%), Gaps = 15/76 (19%) Query: 18 FIKDENGENRYFHVIKVANPDLIKKDAAVTFEPTTNNKGLSAYAVKVIPESKYIYIAGER 77 ++ D G R++ V+ +L+ L + ++ E+ ++Y+AGER Sbjct: 698 YLFDITGNRRFWPVLVPGRANLV---------------WLQKFRGQLFAEALHLYLAGER 742 Query: 78 LKLTSIKSYVVYREEE 93 + + +R E+ Sbjct: 743 YFPSPEDEEIYFRPEQ 758
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 28.9 bits (64), Expect = 0.013 Identities = 14/56 (25%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Query: 11 LKAGLVSSKKMAKVQRTAKKSRVQAREAREAVEENKKAQLERDKQLSEQQKQAVLA 66 + +G + + ++ + AK++ AR+ +AVE N +AQ + Q + +Q++ L+ Sbjct: 308 IPSGELKDDIVEQIAQQAKEAGEVARQ--QAVESNAQAQQRYEDQHARRQEELQLS 361
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 102 bits (256), Expect = 5e-26 Identities = 50/152 (32%), Positives = 69/152 (45%), Gaps = 13/152 (8%) Query: 407 DWAPPPPPRPVIKQVVQGPQTIRLDSMALFDTGKSALKPGSTKLL--VNSLLGIKAKPGW 464 + AP P P VQ + L S LF+ K+ LKP L + S L Sbjct: 195 EAAPVVAPAPAPAPEVQT-KHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDG 253 Query: 465 LIVVAGHTDSIGNDRSNQQLSLKRAEAVRDWMRDTGDVPESCFAVQGYGASRPVASN--- 521 +VV G+TD IG+D NQ LS +RA++V D++ G +P + +G G S PV N Sbjct: 254 SVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKG-IPADKISARGMGESNPVTGNTCD 312 Query: 522 ------ETPEGRAQNRRVEISLVPQKDACLTP 547 + A +RRVEI + KD P Sbjct: 313 NVKQRAALIDCLAPDRRVEIEVKGIKDVVTQP 344
>SECA#SecA protein signature. Length = 901 Score = 56.4 bits (136), Expect = 9e-13 Identities = 16/28 (57%), Positives = 20/28 (71%) Query: 83 IDGTRPLIGRNDPCPCGSGKKFKKCCGQ 110 +GRNDPCPCGSGKK+K+C G+ Sbjct: 872 AQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 5e-21 Identities = 37/152 (24%), Positives = 61/152 (40%), Gaps = 3/152 (1%) Query: 10 ILIVEDEPVFRSLLHGWLTSLGATTFQAEDGKDALHKMTEVHPDLMICDISMPRMNGLEL 69 IL+ +D+ R++L+ L+ G + + DL++ D+ MP N +L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 VETLRNRGEQLPILMISATENMADIAKALRLGVQDVLLKPVKDFDRLRETVYACLYPAMF 129 + ++ LP+L++SA KA G D L KP D L + L A Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRAL--AEP 122 Query: 130 SSRVEEEERLFEDWDALVSNPIAASRLLQELQ 161 R + E +D LV A + + L Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.5 bits (66), Expect = 0.040 Identities = 27/112 (24%), Positives = 44/112 (39%), Gaps = 8/112 (7%) Query: 392 YNTSDLHKKLAIAAASLWRK------NLGIDVKLVNQEWKTFLDTRHQGTYDVARAGWCA 445 YN + ++ I A + G+ V V +E+ F+ + + +G A Sbjct: 28 YNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAA-QTQSSGLTA 86 Query: 446 DYNEPTSFLNTMLSDSSMNTAHYKSPAFDKIMAESVKASDEAQRTAAYAKAE 497 Y E S ++ MLS S+ + A F + A D A R A K+E Sbjct: 87 RY-EQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSE 137
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.008 Identities = 9/16 (56%), Positives = 11/16 (68%) Query: 55 VVGESGCGKSTFARAI 70 + GESG GK ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 229 bits (584), Expect = 2e-77 Identities = 174/241 (72%), Positives = 197/241 (81%), Gaps = 7/241 (2%) Query: 18 MTLDLPRRFPWPTLLSVAIHGAVVAGLLYTSVHQVIEQPSPTQPIEITMVAPADLEPPPA 77 MTLDLPRRFPWPTLLSV IHGAVVAGLLYTSVHQVIE P+P QPI +TMV PADLEPP A Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 78 AQPVVEPVVEPEPEPEPEVAPEPPKEAPVVIHKPEPKPKPKPKPKPKPEKKVEQPKREVK 137 QP EPVVEPEPEPEP PEPPKEAPVVI KP+PKPKPKPKP K + EQPKR+VK Sbjct: 61 VQPPPEPVVEPEPEPEPI--PEPPKEAPVVIEKPKPKPKPKPKPVKKVQ---EQPKRDVK 115 Query: 138 PAAEPRPASPFENNNTAPARTAPSTSTAAAKPTVTAPSGPRAISRVQPSYPPRAQALRIE 197 P E RPASPFEN A T+ + + A +KP + SGPRA+SR QP YP RAQALRIE Sbjct: 116 P-VESRPASPFENTAPA-RLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIE 173 Query: 198 GTVRVKFDVSPDGRIDNLQILSAQPANMFEREVKSAMRRWRYEQGRPGTGVTMTIKFRLN 257 G V+VKFDV+PDGR+DN+QILSA+PANMFEREVK+AMRRWRYE G+PG+G+ + I F++N Sbjct: 174 GQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKIN 233 Query: 258 G 258 G Sbjct: 234 G 234
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 65.6 bits (160), Expect = 7e-14 Identities = 77/373 (20%), Positives = 136/373 (36%), Gaps = 30/373 (8%) Query: 1 MLLGSQFVFNIGFYAVVPFLALFLRDDMLLSGGLI---GLILGLRTFSQQGMFILGGTLA 57 ++L + + +G ++P L LRD ++ S + G++L L Q + G L+ Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRD-LVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 58 DRYGAKAIILAGCVVRVAGFLLLACGASLWPIILGACLTGVGGALFSPSIEALLARAGTH 117 DR+G + ++L + ++A LW + +G + G+ GA + Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGA-------VAGAYI 120 Query: 118 SQANGKRSRAEWFALFAVCGELGAVIGPVAGGVLSGIGFRHIALAGAGIFLLALAVLFFC 177 + RA F + C G V GPV GG++ G A A + L F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180 Query: 178 LPADGHTTTTRRRVPWWTPLRQPRFVAFILAYSSWLLSY------NQLYLALPV--EIQR 229 LP R PL R+ + ++ + + Q+ AL V R Sbjct: 181 LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDR 240 Query: 230 SGGREQDLAPLFMLASLLIITLQLPLA-RFARRMGAVRILPVGFLLLSASFASVALFAAA 288 + +L Q + A R+G R L +G + + +A Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA--- 297 Query: 289 PPAEGWLRLMPAAGFVTLLTLGQMLLVPAAKDLIPLFAEESTLGAHYGALATAGGCAVLA 348 GW+ P + LL G + + PA + ++ +E G G+LA + Sbjct: 298 --TRGWM-AFPI---MVLLASGGIGM-PALQAMLSRQVDEERQGQLQGSLAALTSLTSIV 350 Query: 349 GNLLLGHLLDLAL 361 G LL + ++ Sbjct: 351 GPLLFTAIYAASI 363
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.015 Identities = 10/20 (50%), Positives = 12/20 (60%) Query: 33 LLGPNGCGKSSLLRVLAGLR 52 L G G GKS+L+ L GL Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 37.1 bits (86), Expect = 6e-05 Identities = 36/162 (22%), Positives = 60/162 (37%), Gaps = 28/162 (17%) Query: 6 KVLILGASGGIGGEVARRLVADNWQVRA-----------LKRGAQMRDPEDGIQWIAGDA 54 K L+ GA+G IG V++RL+ QV LK+ + G Q+ D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 LDGGQVAA--AAAGCDVIVH-----AV-----NPPGYRHWRQQVLPMLRNTLQAAERQR- 101 D + A+ + + AV NP Y + L N L+ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD--SNLTGFL-NILEGCRHNKI 118 Query: 102 ALVVLPGTVYNYGPDA-FPLIAEEAAQQPVTRKGAIRVAMEL 142 ++ + YG + P +++ PV+ A + A EL Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL 160
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.9 bits (142), Expect = 3e-13 Identities = 31/183 (16%), Positives = 52/183 (28%), Gaps = 10/183 (5%) Query: 4 FSRYGYEKTTVTDLAKAIGFSKAYIYKFFDSKQAIGEAICASRLEKIMVAVSEAIADAPS 63 FS+ G T++ ++AKA G ++ IY F K + I I E A P Sbjct: 24 FSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPG 83 Query: 64 ASEK-----LRRLFR-ALTEAGSELFFE--DRKLYDIAAVAARDKWPSTEQYAGHLQQLI 115 L + +TE L E K + +A + I Sbjct: 84 DPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA--QRNLCLESYDRI 141 Query: 116 GQILVEGRQAGEFERKTPLDEATLAVYMVMCPFINPVQLQYNLDTAPTAAVLLASLILRS 175 Q L +A A + + + + A +++L Sbjct: 142 EQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEM 201 Query: 176 LSP 178 Sbjct: 202 YLL 204
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 3e-06 Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 70 GKVLERRVETGQSVKRGQLLLRLDPADLALQAQSQQRAVDAARARAKKAANDLARYRGLV 129 V E V+ G+SV++G +LL+L Q ++ AR L + R + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQAR---------LEQTRYQI 155 Query: 130 ASGAISAAEFDQINAAAEAARADLSAAQAQAN 161 S +I + ++ E ++S + Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Score = 31.3 bits (71), Expect = 0.005 Identities = 18/84 (21%), Positives = 32/84 (38%), Gaps = 4/84 (4%) Query: 178 GVVVETLAEPGQVVSAGQVVIRLARAGQREARVQLPETLRPAVGSEALATRYGSESQPV- 236 +V E + + G+ V G V+++L G ++ +L A TRY S+ + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA---RLEQTRYQILSRSIE 161 Query: 237 TATLRLLSDAADATTRTFEARYVL 260 L L + + VL Sbjct: 162 LNKLPELKLPDEPYFQNVSEEEVL 185 Score = 30.2 bits (68), Expect = 0.015 Identities = 12/128 (9%), Positives = 37/128 (28%), Gaps = 15/128 (11%) Query: 103 SQQRAVDAARARAKKAANDLARYRGLVAS--GAISAAEFDQINAAAEA----------AR 150 ++ ++ + A N+L Y+ + I +A+ + Sbjct: 250 AKHAVLEQENKYVE-AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTT 308 Query: 151 ADLSAAQAQANVAQNATGYAGLLADADGVVVE-TLAEPGQVVSAGQVVIRLARAGQR-EA 208 ++ + + + + A V + + G VV+ + ++ + E Sbjct: 309 DNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEV 368 Query: 209 RVQLPETL 216 + Sbjct: 369 TALVQNKD 376
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 438 bits (1128), Expect = e-139 Identities = 233/1055 (22%), Positives = 422/1055 (40%), Gaps = 71/1055 (6%) Query: 8 LSALAVRERSVTLFLIILISVAGLVAFFGLGRAEDPPFTVKQMTVITVWPGATAQEMQDQ 67 ++ +R L I++ +AG +A L A+ P ++V +PGA AQ +QD Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VAEPLEKRLQELKWYDRTETYT-RPGMALITLSLQDQTPP----SEVPEQFYQARKKLGD 122 V + +E+ + + + + G ITL+ Q T P +V + A L Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLL-- 118 Query: 123 EAKNLPAGVSGPMMNDEFADVTFALFAL--KARGEPPRQLVRD--AEALRQQLLHVPGVK 178 P V ++ E + ++ + A + + D A ++ L + GV Sbjct: 119 -----PQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 179 KVNILGEQ-AERIYLSFSHDRLATLGLSPEAIFAALNSQNVLTAAGAI---ETRGGQIF- 233 V + G Q A RI+L D L L+P + L QN AAG + GQ Sbjct: 174 DVQLFGAQYAMRIWLDA--DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 234 --IRLDGAFDRLQQIRDTPIIAG--GRTLKLADVATVERGYEDPATFLIRNQGEPALLLG 289 I F ++ + G ++L DVA VE G E+ R G+PA LG Sbjct: 232 ASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIA-RINGKPAAGLG 290 Query: 290 VVMREGWNGLALGKALDAETTSINQSLPLGMSLTKVTDQSVNISAAVDEFMIKFFVALLV 349 + + G N L KA+ A+ + P GM + D + + ++ E + F A+++ Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 350 VMSVCFVSMG-WRVGVVVAAAVPLTLAVVFVVMEATGKNFDRITLGSLILALGLLVDDAI 408 V V ++ + R ++ AVP+ L F ++ A G + + +T+ ++LA+GLLVDDAI Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 409 IAIEMMV-VKMEEGYDRLKASAYAWSHTAAPMLAGTLVTAVGFMPNGFAQSTAGEYASNV 467 + +E + V ME+ +A+ + S ++ +V + F+P F + G Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 468 FWIVGIALIASWIVAVIFTPWLGVHLLPNRKPAAAGHAALYDT----------PRYQHFR 517 + A+ S +VA+I TP L LL KP +A H H+ Sbjct: 471 SITIVSAMALSVLVALILTPALCATLL---KPVSAEHHENKGGFFGWFNTTFDHSVNHYT 527 Query: 518 RLLTRVIAHKWRVAAGVVALFIVAILGMSVVKKQFFPTSDRPEVLVEVQLPYGSSISQTS 577 + +++ R + ++ + F P D+ L +QLP G++ +T Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 578 AAAAKIEHWLHLQPEVKIVTSYIGQGAPRFYLAMAPELPDP--SFAKLMVLTDGQGARE- 634 ++ + L+ E V S + + + + +F L + G Sbjct: 588 KVLDQVTDYY-LKNEKANVESVFTVNG----FSFSGQAQNAGMAFVSLKPWEERNGDENS 642 Query: 635 --ALKRRLREAV-----ANGLAPEARVRVTQLVFGPYSPYPVAWRVMGPDPHALLDIAER 687 A+ R + + + V + + +G D AL + Sbjct: 643 AEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHD--ALTQARNQ 700 Query: 688 VKSVLQASPL-MRTVNTDWGSRVPVMHFSLNQDRLQASGLSSQSVAQQLQFLLSGIPITT 746 + + P + +V + ++Q++ QA G+S + Q + L G + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 747 VREDIRAVQVIGRAAGDIRLDPAKIADFTLVGSGGQRVPLSQIGDVSIRMEDPLLRRRDR 806 + R ++ +A R+ P + + + G+ VP S P L R + Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 807 TPTITVRGDVAENLQPPDVSTALMKPLQPIIDSLPPGYRIETAGSIEESGKATRAMVPLF 866 P++ ++G+ A P S M ++ + LP G + G + + L Sbjct: 821 LPSMEIQGEAA----PGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALV 876 Query: 867 PIMIALTLLIIILQVRSLSAMVMVFLTAPLGLIGVVPTLLLFNQPFGINALVGLIALSGI 926 I + L + S S V V L PLG++GV+ LFNQ + +VGL+ G+ Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 927 LMRNTLILIGQIHHNQQA-GLDPFHAVVEATVQRARPVLLTALAAILAFIPLTHSVFWGT 985 +N ++++ + G A + A R RP+L+T+LA IL +PL S G+ Sbjct: 937 SAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGS 996 Query: 986 -----LAYTLIGGTLGGTIMTLIFLPAMYAIWFRI 1015 + ++GG + T++ + F+P + + R Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 78.7 bits (194), Expect = 8e-17 Identities = 87/510 (17%), Positives = 181/510 (35%), Gaps = 36/510 (7%) Query: 529 RVAAGVVALFIVA--ILGMSVVKKQFFPTSDRPEVLVEVQLPYGSSISQTSAAAAKIEHW 586 + A V+A+ ++ L + + +PT P V V P + + IE Sbjct: 9 PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQN 68 Query: 587 LHLQPEVKIVTSY-IGQGAPRFYLAMAPELPDPSFAKLMVLTDGQGAREALKRRLREAVA 645 ++ + ++S G+ L DP A++ V Q + L + V Sbjct: 69 MNGIDNLMYMSSTSDSAGSVTITLTFQSGT-DPDIAQVQV----QNKLQLATPLLPQEVQ 123 Query: 646 NGLAPEARVRVTQLVFGPYSPYPVAWRVMGPDPHALLDIAER-VKSVLQASPLMRTVNTD 704 V + + + + D + D VK L + V Sbjct: 124 Q---QGISVEKSSSSYLMVAGFVSDNPGTTQD--DISDYVASNVKDTLSRLNGVGDVQL- 177 Query: 705 WGSRVPVMHFSLNQDRLQASGLSSQSVAQQLQF----LLSGIPITTVREDIRAVQVIGRA 760 +G++ M L+ D L L+ V QL+ + +G T + + A Sbjct: 178 FGAQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 761 AGDIRLDPAKIADFTLVGSG-GQRVPLSQIGDVSIRMED-PLLRRRDRTPTITVRGDVAE 818 + +P + TL + G V L + V + E+ ++ R + P + +A Sbjct: 237 QTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 819 NLQPPDVSTALMKPLQPIIDSLPPGYRIE----TAGSIEESGKATRAMVPLFPIMIALTL 874 D + A+ L + P G ++ T ++ S +V I L Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLS---IHEVVKTLFEAIMLVF 352 Query: 875 LIIILQVRSLSAMVMVFLTAPLGLIGVVPTLLLFNQPFGINALVGLIALSGILMRNTLIL 934 L++ L ++++ A ++ + P+ L+G L F + G++ G+L+ + +++ Sbjct: 353 LVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVV 412 Query: 935 IGQIH-HNQQAGLDPFHAVVEATVQRARPVLLTALAAILAFIPL-----THSVFWGTLAY 988 + + + L P A ++ Q ++ A+ FIP+ + + + Sbjct: 413 VENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSI 472 Query: 989 TLIGGTLGGTIMTLIFLPAMYAIWFRIRPE 1018 T++ ++ LI PA+ A + Sbjct: 473 TIVSAMALSVLVALILTPALCATLLKPVSA 502
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 7e-15 Identities = 34/172 (19%), Positives = 62/172 (36%), Gaps = 6/172 (3%) Query: 7 QKGRPKDPLKTQAILQAARKLFLEQGLE-VTTAEIARVAGVAKATLYANFSDKEHLIEAV 65 +K + + Q IL A +LF +QG+ + EIA+ AGV + +Y +F DK L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 LRQESD--LTISDHDFAQRHHLPLIEVLTAFGYRFVRFINQRELTGWDRLIASAAVRHPD 123 + A+ PL + + + + +I + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 124 LPG--RFYAAGPGRAQQMLEAIIAEAIEAGTLRA-CDPQEAADELAGLWLGM 172 + + + +E + IEA L A + AA + G G+ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.2 bits (60), Expect = 0.005 Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 5 KLVLGAVILGSTLLAGCSSNAKIDQLSSD-VQTLNAKVDQLSNDV 48 KL L A+ LG+TLL GC+S+ Q SD ++ N + + +V Sbjct: 2 KLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNV 46
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 2e-15 Identities = 29/162 (17%), Positives = 61/162 (37%), Gaps = 4/162 (2%) Query: 6 HDEAQSLKARIFSAAIAVFAEHGLSGARMEQIATEAQTTKRMVVYYFKSKEQLYQEVLQH 65 EAQ + I A+ +F++ G+S + +IA A T+ + ++FK K L+ E+ + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 66 VYARIRETEQQLGLENVPPVEALVR---LVRWSVRYHATHADYMRVICMENMQR-GKWLK 121 + I E E + + +++R + + I + G+ Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 122 SSGELKPLNRTALSILEDILLRGQQQGVFQAGLDARDVHRLI 163 + L + +E L + + A L R ++ Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.5 bits (113), Expect = 6e-08 Identities = 69/370 (18%), Positives = 124/370 (33%), Gaps = 43/370 (11%) Query: 64 GILFSAFAWTYALAQIPGGLFLDRFGNKVTYFLSLTLWSLFTLFHGMAVGLKTLLLCRFG 123 GIL + +A G DRFG + +SL ++ A L L + R Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 124 LGISEAPCFPVNSRVVSAWFPQQERAKA----TAVYTVGEYLGLACFAPLLFWIMDGFGW 179 GI+ A V ++ ERA+ +A + G G P+L +M GF Sbjct: 106 AGITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFGMVAG-----PVLGGLMGGFSP 159 Query: 180 RVLFVSVGAVGILFALVWWRCYREPHEDPRLSQQEREHIENGGGLSAPTDQQVAFSWPLV 239 F + A+ L L E H+ R + + +F W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREA-----------LNPLASFRWARG 208 Query: 240 RQLLSKRQIIGASIGQFAGNTVLVFFLTWFPTWLATERHMPWLKVGFFSILPFVAAAGGV 299 +++ + + ++ + E W + + AA G+ Sbjct: 209 MTVVAALMAVFFIMQLVGQVPAALWVIF-------GEDRFHWDA----TTIGISLAAFGI 257 Query: 300 M---FGGWLSDKLLKATGSANLGRKLPIVAGLL--MASCIITANWLESDLAVILVMSFAF 354 + ++ + LG + ++ G++ I+ A +A +++ A Sbjct: 258 LHSLAQAMITGPVAA-----RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLAS 312 Query: 355 FGQGMVGLGWTLISDIAPKGLGGLTGGLFNFCANLAGILTPLVIGFIVAGFGNFFYALIY 414 G GM L ++S + G G +L I+ PL+ I A + + Sbjct: 313 GGIGMPALQ-AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAW 371 Query: 415 IGGAALLGVV 424 I GAAL + Sbjct: 372 IAGAALYLLC 381
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 27.6 bits (61), Expect = 0.042 Identities = 25/121 (20%), Positives = 39/121 (32%), Gaps = 17/121 (14%) Query: 139 VGSRIRDWSIGFVD-------TVADNASCGLYVIGGPAQRPAGLDLKQCAMHMTRNQE-L 190 V + DWS F D V + + G GP D Q A+ T + Sbjct: 16 VADYLADWSAYFGDVNHRPGQVVDGSNTGGFN--PGP------FDGSQYALKSTASDAAF 67 Query: 191 VSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALG-PMVTINEGDSFVAHIE 249 ++ G L + +W +LG+ L G AL V+ + + Sbjct: 68 IAGGDLHYTLFSNPSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLGLDSPIAQ 127 Query: 250 G 250 G Sbjct: 128 G 128
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.0 bits (114), Expect = 4e-08 Identities = 81/404 (20%), Positives = 151/404 (37%), Gaps = 60/404 (14%) Query: 14 VTIGLCFMVALMEGLDLQAAGIAAVGMAQAFALDKMQMGWIFSAGILGLLPGALVGGMLA 73 + I LC + L+ ++ +A F W+ +A +L G V G L+ Sbjct: 15 ILIWLCILS-FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 74 DRHGRKRILLGSVLLFGLFSLATALAWS-FPTLLLARLLTGVGLGAALPNLIA-LTSEAA 131 D+ G KR+LL +++ S+ + S F L++AR + G G AA P L+ + + Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AAAFPALVMVVVARYI 132 Query: 132 GSRFRGRAVSLMYCGVPIGAALAAALGFSGFAAAWQIIFW----IGGVVPLLLIPLLMRW 187 RG+A L+ V +G + A+G I W + ++ ++ +P LM+ Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIG----GMIAHYIHWSYLLLIPMITIITVPFLMKL 188 Query: 188 LPESQAFQRA---------EASVPLRTLFAPGQAAATLLLWLGYFFTLLVVYMLINWLPM 238 L + + + LF + + L++ + F + V ++ P Sbjct: 189 LKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL-IFVKHIRKVTDPF 247 Query: 239 LLVGQGFRASQAAGVMFSLQI-GAACGTLLLGALMDK--------------LTPLRMSLL 283 + G G GV+ I G G + + M K + P MS++ Sbjct: 248 VDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVI 307 Query: 284 IYS---GILAS------LLALGSASSLTGMLLAGFV----------AGLFATGGQSVLYA 324 I+ GIL +L +G L A F+ +F GG S Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 325 LAPLFYPAAIRATGVGTAVA----VGRLGAMSGPLLAGKMLALG 364 + ++++ G ++ L +G + G +L++ Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.020 Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 4/32 (12%) Query: 38 LRPG---ESVALL-GPSGCGKSTLLRLLAGLE 65 + PG + +L G G GKSTL+ L GL+ Sbjct: 589 MEPGCKFDYSVVLEGTGGIGKSTLINTLVGLD 620
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.006 Identities = 63/343 (18%), Positives = 116/343 (33%), Gaps = 23/343 (6%) Query: 48 GLLAALPPAGMMISSFLSPALCRRVEMGVLLSGSLILLALATIASCMTTDMTLLLLPRLL 107 G+L AL + + AL R +L SL A+ + +L + R++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 TGLASGVIIVLGESWITGGAAGSQRATLTGLYASAFTGCQLAGPLL------ISVGPAWQ 161 G+ V G ++I G +RA G ++ F +AGP+L S + Sbjct: 106 AGITGATGAVAG-AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFF 164 Query: 162 TSALIAIVAVTAVCLLMLRHLPTGTRE------SLGERASWRSLGAFLPVLASGVFCFAF 215 +A + + C L+ R + W + L + F Sbjct: 165 AAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQL 224 Query: 216 FDASILALLPLYGMDK-GLNEGLAVLLVTVVLTGDAMFQTPL-GWLADRVGIRRVHLSCA 273 AL ++G D+ + + + ++ Q + G +A R+G RR + Sbjct: 225 VGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGM 284 Query: 274 VVFSLSLLALPLMLGSRIQLMAICLLLGAAAG--ALYTLSLVRAGKTFNGQKLIMINALF 331 + + L + + LL G AL + + + GQ + Sbjct: 285 IADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQ----LQGSL 340 Query: 332 GFFWSAGSVAGPVVSGMLIG--ITGYDGLIVTLVASGVLFLLI 372 S S+ GP++ + IT ++G A+ L L Sbjct: 341 AALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLP 383
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.044 Identities = 12/34 (35%), Positives = 17/34 (50%) Query: 31 VVSLLGPSGSGKTTLLRAVAGLEKPTSGRIAIGN 64 V L G G GK+TL+ + GL+ + IG Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 7e-19 Identities = 29/118 (24%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Query: 7 IIVAEDDDDIAAILTGYLRKAGMKTLRAEDGEQAINLTRLNKPDLLLLDIHLPVYDGWNV 66 I+VA+DD I +L L +AG + DL++ D+ +P + +++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 LTTLRKE-TNVPVIMVTALDQDVDKLMGLRLGADDYVIKPFNPSEVIARVEAVLRRTR 123 L ++K ++PV++++A + + + GA DY+ KPF+ +E+I + L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1060 bits (2744), Expect = 0.0 Identities = 502/1031 (48%), Positives = 690/1031 (66%), Gaps = 7/1031 (0%) Query: 1 MPHFFIERPIFAWVIALFIVLTGLLSIPRLPVAQYPEVAPPGIIISVSYPGASPEVMNTS 60 M +FFI RPIFAWV+A+ +++ G L+I +LPVAQYP +APP + +S +YPGA + + + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVSLIEREISSVDNLLYFESSSDTTGMASITVTFKPGTDIKLAQMDLQNQIKIVESRLPQ 120 V +IE+ ++ +DNL+Y S+SD+ G +IT+TF+ GTD +AQ+ +QN++++ LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 SVRQNGINVEAANSGFLMMVGLKSPSGAYQEADLSDYFARNVTDELRRVPGVGKVQLFGG 180 V+Q GI+VE ++S +LM+ G S + + D+SDY A NV D L R+ GVG VQLFG Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 EKALRIWLDPMKLHSYGLSVTDVLSAISQQNVIVSPGRTGDEPATSSQEVTYPITVKGQL 240 + A+RIWLD L+ Y L+ DV++ + QN ++ G+ G PA Q++ I + + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 SSVEEFRNITIKSQVSAARVTLADVARVESGLQSYAFGIRENGVPATAAAIQLSPGANAI 300 + EEF +T++ + V L DVARVE G ++Y R NG PA I+L+ GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 STASGIRARLTELSGVLPEGMTFTVPFDTAPFVKLSILKVVETFVEAMVLVFFVMLLFLH 360 TA I+A+L EL P+GM P+DT PFV+LSI +VV+T EA++LVF VM LFL Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 KIRCTLIPAIVAPVALLGTFTVMLLSGYSINILTMFGMILAIGIIVDDAIVVVENVERLM 420 +R TLIP I PV LLGTF ++ GYSIN LTMFGM+LAIG++VDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 EDKKMSPQDATREAMREITPAIIGITLVLTAVFIPMAFASGSVGIIYRQFSISMAISILL 480 + K+ P++AT ++M +I A++GI +VL+AVFIPMAF GS G IYRQFSI++ ++ L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SAFLALTLTPALCATLLKP-HGIHQGKSSVFSAWFNAHFHRLTSFYATGLGFVLKRTGRM 539 S +AL LTPALCATLLKP H F WFN F + Y +G +L TGR Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 MMIYAALCLALFAGLSTLPSSFLPDEDQGYFMSSIQLPSDATMQRTLKVVDTFEEEI--A 597 ++IYA + + LPSSFLP+EDQG F++ IQLP+ AT +RT KV+D + Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 HRQAVESNIMILGFGFSGSGQNSAMAFTTLKDWRQRKGT--TAQEEADHIRSQMANVPDA 655 + VES + GF FSG QN+ MAF +LK W +R G +A+ + ++ + D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 656 VTMSLLPPAISDMGTSSGFTYYLQDRGGKGYQALKKAADELIVQANHNP-HLADVYIDGL 714 + PAI ++GT++GF + L D+ G G+ AL +A ++L+ A +P L V +GL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 715 GEGTSLSLHVDREKAEAMGVSFDEINQTISVAAGSNYVNDYTNNGRVQQVIVQADAPYRM 774 + L VD+EKA+A+GVS +INQTIS A G YVND+ + GRV+++ VQADA +RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 775 QPEQLLALSVKNRLGQMLPLSTFVTLSWNVAPQQLIRYQGYPAIRITGSAAQGKSSGTAM 834 PE + L V++ G+M+P S F T W +L RY G P++ I G AA G SSG AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 835 AAMDNLAKHLPPGFAGEWAGSSLQEKESASQLPGLIVLSVLVVFMVLAALYESWSVPFAV 894 A M+NLA LP G +W G S QE+ S +Q P L+ +S +VVF+ LAALYESWS+P +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 895 MLVVPLGLLGAVLAVSVTNMTNDVFFKVGLITLIGLSAKNAILIIEFARQLM-KEGKSLI 953 MLVVPLG++G +LA ++ N NDV+F VGL+T IGLSAKNAILI+EFA+ LM KEGK ++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 954 DATLTAAKLRLRPILMTSLAFTLGVVPLMLASGASDSTQHAIGTGVFGGMISGTLLAIFF 1013 +ATL A ++RLRPILMTSLAF LGV+PL +++GA Q+A+G GV GGM+S TLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1014 VPVFFVTITRF 1024 VPVFFV I R Sbjct: 1021 VPVFFVVIRRC 1031
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (312), Expect = 1e-36 Identities = 74/254 (29%), Positives = 114/254 (44%), Gaps = 10/254 (3%) Query: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGRAMAVKVDVSD 62 K+A +TGA QGIG+A+A L G +A DYN + V S + A A DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 RDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAV 122 + + + +G D++VN AGV I S++ E + +++N GV ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 123 EAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCP 182 + G I+ S V +A Y+SSK A T+ +LA I N P Sbjct: 129 KYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 183 GIVKTPM----WAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPD 238 G +T M WA+ + G F I L +L++P D+A V +L S Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGS-----LETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 239 SDYMTGQSLLIDGG 252 + ++T +L +DGG Sbjct: 243 AGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 4e-33 Identities = 66/255 (25%), Positives = 105/255 (41%), Gaps = 9/255 (3%) Query: 3 LHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAE--VAALGKIPGYHDAD 60 + GK A +TG+ GIG +A+ LA GA + + + + A + AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 61 LRDVGQIEAMMRYAESTFGGVDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTR 120 +RD I+ + E G +DI++N AG+ + ++W ++N + VF+ +R Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 121 LALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVVGLTKTVALETARSGITCNAI 180 M R G I+ + S V +AY ++K A V TK + LE A I CN + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 181 CPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQ---PSGEFVTPQQLGEMALFLCSD 237 PG T + EQ L + P + P + + LFL S Sbjct: 186 SPGSTETDMQWSLWADENGA----EQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 238 AAAQVRGAAWNMDGG 252 A + +DGG Sbjct: 242 QAGHITMHNLCVDGG 256
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 29.5 bits (66), Expect = 0.028 Identities = 32/129 (24%), Positives = 47/129 (36%), Gaps = 15/129 (11%) Query: 7 ALAALALLMLAAYRGY----SVILFAPIAALGAVLLTDPGAVGPA----------FTGLF 52 ALA + ++AA GY S++ P+ AL + G V A + L Sbjct: 126 ALAGAGIGVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLV 185 Query: 53 MEKMVGFVKLYFPVFLLGAVFGKLIELSGFSRSIVAAAIRILGRRHAIPVIVLVCALLTY 112 + ++ FPV L VF S SI +LG + V V AL Y Sbjct: 186 ITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHP-VVDVCQHVGALCIY 244 Query: 113 GGVSLFVVA 121 + F+ Sbjct: 245 IVIPFFLST 253
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.024 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 53 ITLLGPSGCGKSTLLKMVAGLVEPSDGKLMLW-RRDSREKAQ 93 + L G G GKSTL+ + GL SD + +DS E+ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIA 640
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 31.8 bits (72), Expect = 0.005 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 9/72 (12%) Query: 188 LVSRYHDPRPDSLRRVVMAPTTVLHSAPGAQ-LREMAKLARQLGIRL------HSHLSET 240 + S + P P+ L R+ AP + + G Q L K ++ L +HL++ Sbjct: 101 VWSAGYGPSPEMLARI--APGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQY 158 Query: 241 VDYLDAARQKFA 252 D++ + + +F Sbjct: 159 EDFIRSMKPRFV 170
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 66.8 bits (163), Expect = 3e-15 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 3/163 (1%) Query: 39 PAIQQSLGGSPAALSWLTNGFMLTFGSFLLAAGVTADAIDRKRIFIAGAALLCLSSLLFC 98 P I PA+ +W+ FMLTF G +D + KR+ + G + C S++ Sbjct: 38 PDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGF 97 Query: 99 LTHNLFLSGVL-RALQGLAAAMILASGSAALAQLYDGAQRTRAFSILGTVFGIGLAFGPL 157 + H+ F ++ R +QG AA A +A+ R +AF ++G++ +G GP Sbjct: 98 VGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPA 157 Query: 158 LIGFMIDAVGWRGVYALFALLSAGVLLIGLVSLPATEKASRGH 200 + G + + W + + + V L+ L E +GH Sbjct: 158 IGGMIAHYIHWSYLLLIPMITIITVPF--LMKLLKKEVRIKGH 198
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.9 bits (106), Expect = 2e-07 Identities = 36/195 (18%), Positives = 76/195 (38%), Gaps = 10/195 (5%) Query: 14 GFLSLTTLALLIASGGLFVAFVVRCRRVNNPVLELSLLRHPRFVGVLLLPVATCCCYVVL 73 FL ++ L+ LI FV R+V +P ++ L ++ F+ +L Sbjct: 224 SFLIVSVLSFLI--------FVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGF 275 Query: 74 LIIVPLHFMGGEGMSESQ-SALYLMALTTPMLVFPSVAALLTRWFSPGQVSTAGLMMASV 132 + +VP +S ++ ++ + T +++F + +L P V G+ SV Sbjct: 276 VSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV 335 Query: 133 GLLLLGDAFHSNHLPQLVLALILCGAGAALPWGLMDGLAISAVPVAKAGMAAGLFNTVRV 192 L + + ++ G + ++ + S++ +AG L N Sbjct: 336 SFLTASFLLETTSWFM-TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394 Query: 193 AGEGIALAVVSAVLT 207 EG +A+V +L+ Sbjct: 395 LSEGTGIAIVGGLLS 409 Score = 28.3 bits (63), Expect = 0.036 Identities = 20/89 (22%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Query: 121 QVSTAGLMMASVGLLLLGD---AFHSNHLPQLVLALILCGAGAALPWGLMDGLAISAVPV 177 Q+ L++ + + G + L++A + GAGAA L+ + +P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 178 AKAGMAAGLFNTVRVAGEGIALAVVSAVL 206 G A GL ++ GEG+ A+ + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.002 Identities = 15/44 (34%), Positives = 20/44 (45%) Query: 23 PAYANPGNGNGNGGGNHGNSGNHGNSGNHGNNGNSGDHGNKGQN 66 +++ N G G G+ + G GN G NGNSG G N Sbjct: 37 SGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 29.7 bits (66), Expect = 0.006 Identities = 13/39 (33%), Positives = 16/39 (41%) Query: 27 NPGNGNGNGGGNHGNSGNHGNSGNHGNNGNSGDHGNKGQ 65 NP G G + G HGN G +GN+G G Sbjct: 44 NPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLS 82 Score = 29.7 bits (66), Expect = 0.007 Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 26 ANPGNGNGNGGGNHGNSGNHGNSGNHGNNGNS 57 + G G+G GN G +GN G G N ++ Sbjct: 52 SGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.038 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 33 VGGVSFNIRPGTIFG----LVGESGSGKTTVGRTLLGLYEKSAGSVKFH 77 +G V+ + PG F L G G GK+T+ TL+GL S Sbjct: 582 MGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 30.2 bits (68), Expect = 0.004 Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 5/44 (11%) Query: 10 QRQALICQILQENGRVVCAELAARLQ-----VSEHTIRRDLHEL 48 QR I +I+ N EL L+ V++ T+ RD+ EL Sbjct: 5 QRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKEL 48
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 3e-06 Identities = 22/148 (14%), Positives = 44/148 (29%), Gaps = 10/148 (6%) Query: 12 KAEQQAAPVDAPAAEPVDPRKAAVEAAIARAKARKAEQQAAPVDAPAAEPVDPRKAAVEA 71 + E++ VD + +A V + + + +A PV P A + Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEA---------PVPPPAPATPS 1034 Query: 72 AIARAKARKAEQQAAPVDAPAVKPVDPRKAAVEAAIARAKARKAEQQATQQD-LASAAAN 130 A ++Q++ V+ + E A KA Q + S Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 131 DDPRKAAVAAAIARVQARKATQQAVNEE 158 + A + + + K + E Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEV 1122 Score = 37.0 bits (85), Expect = 2e-05 Identities = 21/145 (14%), Positives = 43/145 (29%), Gaps = 10/145 (6%) Query: 2 EAAIARAKARKAEQQAAPVDAPAAEPVDPRKAAVEAAIARAKARKAEQQAAPVDAPAAE- 60 + A ++Q++ V+ + + E A KA Q V +E Sbjct: 1033 PSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 61 ----PVDPRKAAVEAAIARAKARKAEQQAAPVDAPAVKPVDPRKAAVEAAIARAKARKAE 116 + ++ A +AK + Q P V P + V + +A A Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV-----QPQAEPAR 1147 Query: 117 QQATQQDLASAAANDDPRKAAVAAA 141 + ++ + + A Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPA 1172 Score = 33.1 bits (75), Expect = 4e-04 Identities = 27/160 (16%), Positives = 48/160 (30%), Gaps = 13/160 (8%) Query: 2 EAAIARAKARKAEQQAAPVDAPA-AEPVDPRKAAVEAAIARAKA-RKAEQQAAPVDAPAA 59 ++ A APV PA A P + + E + +K K EQ A Sbjct: 1007 VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDAT------- 1059 Query: 60 EPVDPRKAAVEAAIARAKARKAEQQAAPVDAPAVKPVDPRKAAVEAAIARAKARKA-EQQ 118 + E A KA Q V + + + + K KA + Sbjct: 1060 ---ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 119 ATQQDLASAAANDDPRKAAVAAAIARVQARKATQQAVNEE 158 Q++ + P++ + + + VN + Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Score = 33.1 bits (75), Expect = 4e-04 Identities = 15/145 (10%), Positives = 40/145 (27%), Gaps = 7/145 (4%) Query: 7 RAKARKAEQQAAPVDAPAAEPVDPRKAAVEAAIARAKARKAEQQAAPVDAPAAEPVDPRK 66 +AK + Q P P + V+ A+ + D + Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 67 AAVEAAIARAKARKAEQQAAPVDAPAVKPVDPRKAAVE-------AAIARAKARKAEQQA 119 A E + + ++ P + A + + + + R++ + Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV 1230 Query: 120 TQQDLASAAANDDPRKAAVAAAIAR 144 + +++D A+ + Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTST 1255
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 7e-05 Identities = 24/143 (16%), Positives = 47/143 (32%), Gaps = 19/143 (13%) Query: 437 RQEKAEIAAIRQEEQRAAEAKARFEA---------------RQARLEREKAARAERHKKA 481 + E+ Q + A EAK+ +A E ++ A E+ +KA Sbjct: 1053 KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 482 AVQPAAKDQEAISAALARVRDKQRDAAQPIVIQAGAKPDNSEAIAAREARKAEARARKAQ 541 V+ + + + +Q + QP QA +N + +E +++ Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQP---QAEPARENDPTVNIKEP-QSQTNTTADT 1168 Query: 542 QQAAPMVAPAAEPVDPRKAAVEA 564 +Q A + E V Sbjct: 1169 EQPAKETSSNVEQPVTESTTVNT 1191
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 42.6 bits (100), Expect = 2e-06 Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 2/146 (1%) Query: 28 LDSMAVSLKVSPGMIGSVITATQAGYAIGLLFLVPLGDWLNRKYVVMSQLLLSVAALVAA 87 L +A P V TA ++IG L D L K +++ ++++ V Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 88 GLSPNIVTLL-GAMLIVGLMAVVVQVLVAW-VAILATPQKRGQAVGTLTSGIVSGILLSR 145 + + +LL A I G A LV VA + RG+A G + S + G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 146 FISGAIADIAGWRAVYLTAACLMLMI 171 I G IA W + L ++ + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITV 182
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.012 Identities = 8/35 (22%), Positives = 14/35 (40%) Query: 83 QGVGSGQSDSALAGRDWHSPANLNDGAAASSMSLL 117 G+G + L G D+ S + + G S + Sbjct: 605 GGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQI 639
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.044 Identities = 28/132 (21%), Positives = 48/132 (36%), Gaps = 27/132 (20%) Query: 11 PRILQWLLAGLMLIIGLAVGILGAKLALVGGTLYFALMGVVMVIAAVLIFRNRRGGILLY 70 P W+ ML + + G + + I +L+F GI++ Sbjct: 48 PASTNWVNTAFMLTFSIGTAVYGK-------------LSDQLGIKRLLLF-----GIIIN 89 Query: 71 AVAFIASVIWAISDAGWNYWPLFSRLF-ALGVLAFLAALVWPFLAS--PPAKKGPAYGVA 127 SVI + + + + +R G AF ALV +A P +G A+G+ Sbjct: 90 C---FGSVIGFVGHSFF-SLLIMARFIQGAGAAAFP-ALVMVVVARYIPKENRGKAFGLI 144 Query: 128 AVLAVALAVSFG 139 + VA+ G Sbjct: 145 GSI-VAMGEGVG 155
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.007 Identities = 12/31 (38%), Positives = 14/31 (45%) Query: 38 LLGPSGCGKSTLLRLLAGLSVPASGEIRFGD 68 L G G GKSTL+ L GL + G Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 51.9 bits (124), Expect = 1e-10 Identities = 26/180 (14%), Positives = 64/180 (35%), Gaps = 11/180 (6%) Query: 5 QRDARREGIMQAAMRLALRGGFAAMTVRQIAREAQVAAGQLHHHFTSIGELKAQVFIRLI 64 + R+ I+ A+RL + G ++ ++ +IA+ A V G ++ HF +L ++++ Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 65 REMLDMPLVAED-------ASWRERL---FSMIGSEDGRLEPYIRLWREGQVLADSDPDI 114 + ++ L + + RE L +E+ R + + + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERR-RLLMEIIFHKCEFVGEMAVV 126 Query: 115 KAAYLLTMNMWHAETVAIIEQGLASGEFRSAEPAADIAWRFIALVCGLDGIYALDAQALD 174 + A + ++ + + + A + GL + Q+ D Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD 186
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.1 bits (138), Expect = 4e-11 Identities = 81/390 (20%), Positives = 135/390 (34%), Gaps = 37/390 (9%) Query: 5 IFSLALGTFGLGMAEFGIMGVLPDMAHDVGISIPAA---GNMIAWYAFGVVIGAPIMALL 61 + ++AL G+G+ IM VLP + D+ S G ++A YA AP++ L Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRFSLKSVMLFLAGLCILGNTLFTFSSSYAMLALGRLVSGFPHGAFFGVGAIILSKIAP 121 S RF + V+L + + + +L +GR+V+G GA I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMIGGMTIANLVGVPGGTWLGHHFSWRYTFALIAVFNVAVFLAIFCWVPTL 181 G A G + +V P L FS F A N FL +P Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 182 YDRASTRLREQ---------FRFLASPAPWLI---FAATMFGNAGVFAWFSYIKPFMLNV 229 + LR + + + L+ F + G W + + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE------ 238 Query: 230 SGFAESKMMLIMMLAGLGM---VVGNLLSGKISGRYSPLRIAAMTDGVIAVTLLLIFAFG 286 F + + LA G+ + +++G ++ R R + +L+ Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 287 EHKVASLALAFLCCAGLFALSAPLQILLLQNAKGGEMLGAAGGQIAF--NLGSAIGAFCG 344 +A + L G+ LQ +L + E G G +A +L S +G Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVGPLLF 355 Query: 345 GMMIAQGFG-WNS-VALPAAALSFLAMSAL 372 + A WN + AAL L + AL Sbjct: 356 TAIYAASITTWNGWAWIAGAALYLLCLPAL 385
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 4e-25 Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Query: 6 HILVVDDDRDIRELIVDYLEKSGYRASGAANGKAMWSVLKNHQIDLIVLDIMMPGEDGLT 65 ILV DDD IR ++ L ++GY +N +W + DL+V D++MP E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 LCRQLRANPQQDIPVLMLTARTDDSDRILGLEMGADDYLIKPFVARELLARIKAILRRTR 125 L +++ + D+PVL+++A+ I E GA DYL KPF EL+ I L + Sbjct: 65 LLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 126 ALPPNLQ 132 P L+ Sbjct: 124 RRPSKLE 130
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 57.3 bits (138), Expect = 2e-12 Identities = 28/106 (26%), Positives = 50/106 (47%) Query: 54 ADNESTAIHPDVAPAENEVVIVKRRVGAFSFTELEMILRAQGIENLILTGVTTSRVVLST 113 + I ++AP ++++V+ K R AF T L ++R +G + LI+TG+ L T Sbjct: 101 SGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVT 160 Query: 114 VGQAFDLDYRLIVVNDYCADPDPDTNMFLLKKVLPQHAFVTSSSEI 159 +AF D + V D AD + + L+ + AF + + Sbjct: 161 ACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSL 206
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 97.3 bits (242), Expect = 9e-24 Identities = 81/408 (19%), Positives = 157/408 (38%), Gaps = 21/408 (5%) Query: 27 MCVGMFIALIDIQIVSASLRDIGGGLSAGDDETVWVQTSYLIAEIIIIPLSGWLARVMST 86 +C+ F ++++ +++ SL DI + T WV T++++ I + G L+ + Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 87 RWLFAASAAGFTLMSLLCGWAWNIQS-MIAFRALQGLAGGSMIPLVFTTAFAFFQGKQRV 145 + L S++ + S +I R +QG + LV + + R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 146 IAAATIGGLASLAPTLGPTVGGWITENYNWHWLFFINVVPGIYIAVAVPLLVKVDSADPT 205 A IG + ++ +GP +GG I +W +L I ++ I + + LL K Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGH 198 Query: 206 LLRGADYLSILLLALSLGCLEYTLEEGPRWGWFDDATLTTTAWVALLCGVAFVIRTLRHP 265 D I+L+++ + F + + V++L + FV + Sbjct: 199 F----DIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVT 244 Query: 266 QPVMDLRALQDRTFSLGCYFSFMAGVGIFATIYLTPLYLGSVRGFSALEIGLAV-FSTGL 324 P +D ++ F +G + + + + P + V S EIG + F + Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTM 304 Query: 325 FQVMSIPFYSWLANRVDLRWLLMAGLIGFAVSMY--SFVPITHDWGADQLLLPQAFRGLA 382 ++ L +R ++L G+ +VS SF+ T W +++ GL+ Sbjct: 305 SVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTIIIVFVLGGLS 363 Query: 383 QQFAVAPTVTLTLGSLPPARLKLASGLFNLMRNLGGAIGIALCGTVLN 430 V T+ + SL L N L GIA+ G +L+ Sbjct: 364 FTKTVISTIVSS--SLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 88.0 bits (218), Expect = 2e-21 Identities = 41/284 (14%), Positives = 79/284 (27%), Gaps = 69/284 (24%) Query: 44 VGGDISAISSKVSGYIQQLAVQDNMAVKKGDLLIRIDDRDYRAALAK------------- 90 G I + ++++ V++ +V+KGD+L+++ A K Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151 Query: 91 ----------------------------AAGEVAAQ-----------QAALADIQATRQL 111 + EV Q + Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Query: 112 QQATIAGSAASLLAATAATEKLANDNRRYNALAASSAISAQIRDNASADYRRAHAEQEKA 171 ++A A + + + +++L AI+ Y A E Sbjct: 212 KRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVY 271 Query: 172 KADKTVAERQLAVLDARHQQ--------ILAALAQAQAN-------LEMARLNLSYTDIR 216 K+ E ++ +Q IL L Q N L + IR Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIR 331 Query: 217 APFDGVIGNRRAWS-GSFVSSGTQLLSLVPA-HGLWIDANFKET 258 AP + + + G V++ L+ +VP L + A + Sbjct: 332 APVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNK 375
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.0 bits (88), Expect = 3e-06 Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 1/62 (1%) Query: 68 NRLWALISALVIEESSRGSGIGQQLLQAAERLARDKQCAQIELSSSEKRIRAHQFYENNG 127 N ALI + + + R G+G LL A A++ + L + + I A FY + Sbjct: 87 NGY-ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHH 145 Query: 128 YK 129 + Sbjct: 146 FI 147
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.1 bits (65), Expect = 0.020 Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 13/72 (18%) Query: 58 RLGYDKYKDMRDELRTL-------RQSGMPLTDQRDAV------QGNTLLARHYKQEMAN 104 L Y K D+ + L + +Q+ P+ + Q N L+ M + Sbjct: 273 YLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMND 332 Query: 105 LTQWVNALDARQ 116 L + + LD R+ Sbjct: 333 LERVIAQLDIRR 344
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.015 Identities = 13/42 (30%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 31 VISIIGRSGSGKSTLLRCINGLEGYQEGSIKLGGMTITNRDS 72 + + G G GKSTL+ + GL+ + + +G T +DS Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG----TGKDS 635
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 1e-16 Identities = 31/171 (18%), Positives = 58/171 (33%), Gaps = 15/171 (8%) Query: 2 KPKQADILRHASTLFNREGYQSPSIERIAEHAGISKMTFYRYYADKEALILAILKQKESE 61 + + IL A LF+++G S S+ IA+ AG+++ Y ++ DK L I + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL-SES 68 Query: 62 FMQDLAQITADK------ASAREKLFAVFDYYHRWFTCETFHGCMFTRALFEYGASSPAI 115 + +L K + RE L V + +F + F + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 116 REQCSRFKSLLWQFFRDILL------QVLKPEPAERVAMMMVMLIDGAIAA 160 ++ + L + R A++M I G + Sbjct: 129 AQRN--LCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 49.1 bits (117), Expect = 2e-08 Identities = 58/341 (17%), Positives = 107/341 (31%), Gaps = 40/341 (11%) Query: 70 VTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLATLWL---VY 126 + +L ++Q +P G L ++FG R ++ + A + + + A L L++ V Sbjct: 47 ILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 127 GCMGGLGTG----IVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLTTN 182 G G G I I + F GF + G G ++ S Sbjct: 107 GITGATGAVAGAYIADITDGDERARHF----GFMSACFGFGMVAGPVLGGLMGGFSP--- 159 Query: 183 GLEHTMTTFGILFALVGFIASQ-GLKLPPPAVSQPVSQTVVQSSRSFTSREMLRQPLFWL 241 H + F+ L +P+ + + SF + + L Sbjct: 160 ---HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMT-VVAAL 215 Query: 242 MFVMMAMMSTSG-------LMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLT 294 M V M + + A GIS A + +L A+ Sbjct: 216 MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM---------- 265 Query: 295 RPLFGFISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFP 354 + G ++ R G + + + +G +L + F ++ V+ G Sbjct: 266 --ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIM--VLLASGGIGMPALQ 321 Query: 355 STLTDTFGSEHAATNYGWLYISQGIGSIFGGPLAALLYQYT 395 + L+ E G L + SI G L +Y + Sbjct: 322 AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Score = 34.4 bits (79), Expect = 7e-04 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Query: 296 PLFGFISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGW-GEIFSLFP 354 P+ G +SDRFGR + ++ A V + P L+VL G + G G ++ Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMAT---APFLWVLYIGRIVAGITGATGAVAG 117 Query: 355 STLTDTFGSEHAATNYGWLYISQGIGSIFGGPLAALLYQYTHGWHVVFSCAIGLDFITAA 414 + + D + A ++G++ G G + G L L+ ++ H F A L+ + Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP--HAPFFAAAALNGLNFL 175 Query: 415 LALWVLKP 422 ++L Sbjct: 176 TGCFLLPE 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.013 Identities = 26/141 (18%), Positives = 48/141 (34%), Gaps = 4/141 (2%) Query: 18 MVIAFVQFTNALEYMMFSPVFTFMAADF---AVPVTFSGYVSGMYTSGAVLSGIIAFYWI 74 +VI +A+ + PV + D G + +Y + Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 75 DRCNKKHFLIANMVLLAMATLLTTFTTSFPLLLTLRFFAGLVGGTTMAVGITILINHTPA 134 DR ++ L+ ++ A+ + +L R AG+ G T AV + + T Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDG 126 Query: 135 DLRGKMLATVIASFSMVSIVG 155 D R + + A F + G Sbjct: 127 DERARHFGFMSACFGFGMVAG 147
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.4 bits (66), Expect = 0.014 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 3/40 (7%) Query: 41 LTHPD-GFTLIDGGLAVEGLKDPSGYWG-SAVEQFKPVMS 78 L HP+ F + G+ + G PSG W A +PVM+ Sbjct: 196 LWHPEAHFDWVRPGIILYGAS-PSGQWRDIANTGLRPVMT 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.008 Identities = 14/43 (32%), Positives = 16/43 (37%), Gaps = 5/43 (11%) Query: 26 VLGLVGDNGAGKSTLTKVLSGA-----VIPSSGTIRIDGEQQQ 63 + L G G GKSTL L G GT + EQ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIA 640
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.8 bits (64), Expect = 0.022 Identities = 10/40 (25%), Positives = 21/40 (52%) Query: 12 LSDVAKLAGLSKATLSRYMNNSIVLPQDTIDRIETAIREL 51 L ++AK AG+++ + + + L + + E+ I EL Sbjct: 34 LGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGEL 73
>INTIMIN#Intimin signature. Length = 939 Score = 32.7 bits (74), Expect = 4e-04 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 7/70 (10%) Query: 84 SDGVKVTQSGAESR-FYTVKSGDTLSAISKAMYGSANEYQRIFEANKPMLTHPD---KIY 139 SD +T + ++R FYT+K+G+T++ +SK+ + + I+ NK + + K Sbjct: 49 SDSKLLTHNSYQNRLFYTLKTGETVADLSKSQDINLST---IWSLNKHLYSSESEMMKAE 105 Query: 140 PGQVLIIPAK 149 PGQ +I+P K Sbjct: 106 PGQQIILPLK 115
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 30.6 bits (69), Expect = 0.010 Identities = 5/35 (14%), Positives = 15/35 (42%), Gaps = 4/35 (11%) Query: 312 QRLVQRMFDTAISFRLAQLKDAWRALHSAEVRLKR 346 +++ + LA ++++W + RL + Sbjct: 150 NSVMEGVIVRI----LANVRESWTQVIDLRPRLGQ 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 245 bits (627), Expect = 1e-78 Identities = 114/474 (24%), Positives = 194/474 (40%), Gaps = 73/474 (15%) Query: 7 SILLIDDDADVLDAYTQLLEQAGYHVSACNNPFDAREQVPKDWPGIVLSDVCMPGCSGID 66 +IL+ DDDA + Q L +AGY V +N + +V++DV MP + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 LMTLFHQDDDLLPILLITGHGDVPMAVEAVKKGAWDFLQKPIDPGKLLTLVDAALRQRQS 126 L+ + LP+L+++ A++A +KGA+D+L KP D +L+ ++ AL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 127 VIARRQYCQQKLQVELIGRSQWTVRYRQRLQQLAETDIAVWLYGEPGTGRMTGARYLHQL 186 ++ + Q L+GRS + L +L +TD+ + + GE GTG+ AR LH Sbjct: 125 RPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 187 GRHAEGPFIA--CELTPAN----------------AHTLNE-LIAQAQGGTLVLSHPEHL 227 G+ GPF+A P + A T + QA+GGTL L + Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 228 THEQQHQLVQ-LQSHEKRP----------FRLIGIGSASLVELAASSQIVAELYYCFAMT 276 + Q +L++ LQ E R++ + L + +LYY + Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 277 QIGCQPLSKRPDDIEPLFHHYLQKTCQRLNHPVPEVDAGLLKGMMRRVWPNNVRELANAA 336 + PL R +DI L H++Q+ + V D L+ M WP NVREL N Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 337 ELFAV--------------------------------GVLPLAETVNPLMH--------- 355 G L +++ V M Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 356 IGEPTPLDQRVEDVERQIITEALNIHQGRINEVAEYLLIPRKKLYLRMKKYGLN 409 + D+ + ++E +I AL +G + A+ L + R L ++++ G++ Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (311), Expect = 1e-36 Identities = 74/254 (29%), Positives = 121/254 (47%), Gaps = 12/254 (4%) Query: 3 LASKTAIVTGAARGIGFGIAQVLAREGARVIIADRDAHG-EAAAASLRESGAQALFISCN 61 + K A +TGAA+GIG +A+ LA +GA + D + E +SL+ A + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 IAEKTQVEALFSQAEEAFGPVDILVNNAGINRDAMLHKLTEADWDTVIDVNLKGTFLCMQ 121 + + ++ + ++ E GP+DILVN AG+ R ++H L++ +W+ VN G F + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 QAAIRMRERGAGRIINIAS-ASWLGNVGQTNYSASKAGVVGMTKTACRELAKKGVTVNAI 180 + M +R +G I+ + S + + Y++SKA V TK ELA+ + N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 181 CPGFIDTDMTRG--VPENVWQIMIS--------KIPAGYAGEAKDVGECVAFLASDGARY 230 PG +TDM EN + +I IP + D+ + V FL S A + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 231 INGEVINVGGGMVL 244 I + V GG L Sbjct: 246 ITMHNLCVDGGATL 259
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 26.1 bits (57), Expect = 0.045 Identities = 10/24 (41%), Positives = 18/24 (75%) Query: 13 QLQRTHKKIYRHLMPLLIVAYIIS 36 ++Q+TH+KI R L+ L +V ++S Sbjct: 2 EIQQTHRKINRPLVSLALVGALVS 25
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.016 Identities = 26/157 (16%), Positives = 48/157 (30%), Gaps = 13/157 (8%) Query: 131 STRVFLLLVLIYFTHQFSVYGLSYFLPGIIGSWGQLTPLQVGLLTAIP-----WIAAAAG 185 F++ VL +V G +P ++ QL+ ++G + P I G Sbjct: 254 KNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIG 313 Query: 186 GILLPRFARTEQRSRSMLMAGYLVMATGMAIGAIAGHG---VALLGFSLAAFMFFAMQSI 242 GIL+ R +L G ++ + + +++ Sbjct: 314 GILVDRRG-----PLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 243 IFNWLPSIMSGHMLAGSFGLLNCLGLCGGFLGPFILG 279 I + S + LLN G I+G Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 71/399 (17%), Positives = 134/399 (33%), Gaps = 51/399 (12%) Query: 53 EMILRLG-PVISKEFSLSPEQWGNIVALIMVALAVLDIPGSIWSDRYGSGWKRARFQVPL 111 EM+L + P I+ +F+ P + M+ ++ SD+ G + L Sbjct: 30 EMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLG-------IKRLL 82 Query: 112 VLGYTALSFISGIKAISHGLTAFVLL-RVGVNLGAGWGEPVGVSNTAEWWPKEKRGFALG 170 + G F S I + H + +++ R GA + + A + PKE RG A G Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 171 VHHTGYPIGALLSGVVASLVLATFGEGSWRYCFLL--ALLVAIPLMIFWAKYSTADRINT 228 + + +G + + ++ W Y L+ ++ +P ++ K RI Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIH---WSYLLLIPMITIITVPFLMKLLK--KEVRIK- 196 Query: 229 LYQHIDSQG----------LTRPATQES---------------SHVAKGEGMKTFLRTLR 263 H D +G T S H+ K + Sbjct: 197 --GHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGK 254 Query: 264 NRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSLAASAGLSIIF--TLTGTLGQVIW 321 N + + G ++P + V LS A G IIF T++ + I Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAE-IGSVIIFPGTMSVIIFGYIG 313 Query: 322 PWLSDSFGRKRTLIVCGLWMSIG---IALFYFATNMPRLIAIQLFFGLVANAVWPIYYAM 378 L D G L + ++S+ + T+ I I G ++ + + Sbjct: 314 GILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLS-FTKTVISTI 372 Query: 379 ASDSAEERATSTANGIITTAMFIGGGISPLLMGWLIQFG 417 S S +++ ++ F+ G ++G L+ Sbjct: 373 VSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 28.8 bits (64), Expect = 0.012 Identities = 13/50 (26%), Positives = 30/50 (60%), Gaps = 2/50 (4%) Query: 296 INNVRQLLEHDSGEVLLDTLSSFIANNAEPGKTSLLLGIHRNTLTYRLQQ 345 +N++ +L+ + + LLD + + N + +L++GI+R TL +L++ Sbjct: 47 VNDLYELVLAEVEQPLLDMVMQYTRGNQT--RAALMMGINRGTLRKKLKK 94
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 2e-05 Identities = 26/118 (22%), Positives = 48/118 (40%), Gaps = 1/118 (0%) Query: 55 GLVMSVLLVGAALGSVFGGKFADYFGRRKYLLFLSFVFLIGALLSAAAPDITTLLIARAL 114 G+++++ + + G +D FGRR LL + + A AP + L I R + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 115 LGYAVGGASVTAPTFISEVAPTEMRGKLTGLNEVAIVIGQLAAFAINAIIGIIWGHLP 172 G G A +I+++ + R + G G +A + ++G H P Sbjct: 106 AGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP 162 Score = 32.5 bits (74), Expect = 0.004 Identities = 32/137 (23%), Positives = 51/137 (37%), Gaps = 22/137 (16%) Query: 321 LVDRFKRKTIIIYGFAIMATLHLIIAAVDYTLVGDLKATAIWLLGALFVGVMQGSMGFIT 380 L DRF R+ +++ L AAVDY ++ + +G + G + G+ G + Sbjct: 66 LSDRFGRRPVLLVS--------LAGAAVDYAIMATAPFLWVLYIGRIVAG-ITGATGAVA 116 Query: 381 WVVLAELFPLKFRGLSMGISVFFMWIMNAVVSYLFPL------LQAKLGLGPVFFIFAAI 434 +A++ R G M+A + L FF AA+ Sbjct: 117 GAYIADITDGDERARHFGF-------MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAAL 169 Query: 435 NYLAILFVVFALPETSN 451 N L L F LPE+ Sbjct: 170 NGLNFLTGCFLLPESHK 186 Score = 30.2 bits (68), Expect = 0.018 Identities = 30/152 (19%), Positives = 51/152 (33%), Gaps = 8/152 (5%) Query: 48 ALTPTTEGLVMSVL-LVGAALGSVFGGKFADYFGRRKYLLFLSFVFLIGALLSAAAPDIT 106 TT G+ ++ ++ + ++ G A G R+ L+ G +L A A Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 107 TLLIARALLGYAVGGASVTAPTFISEVAPTEMRGKLTGLN----EVAIVIGQLAAFAINA 162 LL + G +S E +G+L G + ++G L AI A Sbjct: 302 MAFPIMVLLA-SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 163 IIGIIWGHLPDVWRYMLLVQAIPAICLFVGMW 194 W W + + L G+W Sbjct: 361 ASITTWNGW--AWIAGAALYLLCLPALRRGLW 390
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 26.5 bits (58), Expect = 0.013 Identities = 12/35 (34%), Positives = 18/35 (51%), Gaps = 6/35 (17%) Query: 11 LCLAPLASSAALSGQVH------FSGRVINPACVI 39 LCL + + +S VH F G++I PAC + Sbjct: 7 LCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTV 41
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 32.7 bits (74), Expect = 4e-04 Identities = 40/168 (23%), Positives = 75/168 (44%), Gaps = 22/168 (13%) Query: 24 ARAAGTLNFTGKIINESCQIANNGGDVNVDFGNVDMSALKSHEAKTAETPFTINLTGCPL 83 AA L F GK+I +C + N V++G++++ L ++ + FT+++ CP Sbjct: 22 VHAADNLTFKGKLIIPACTVQN----AEVNWGDIEIQNLV--QSGGNQKDFTVDMN-CPY 74 Query: 84 AQNISISLEGTPDTNANGTSAAVLALSDSADTAKGVGIEVFSSPDGS-----TEGTQLTF 138 S+ T+ T ++L + S + G+ I +++S + T G+Q+T Sbjct: 75 ----SLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGNAVTLGSQVTP 130 Query: 139 DKQSKTAVSQADENGDIAFNFIADVKSDSSQDVTAGNINATANIDIVY 186 K + TA ++ I K + Q + AG +ATA + Y Sbjct: 131 GKITGTAPAR-----KITLYAKLGYKGN-MQSLQAGTFSATATLVASY 172
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 680 bits (1757), Expect = 0.0 Identities = 311/861 (36%), Positives = 451/861 (52%), Gaps = 52/861 (6%) Query: 12 VSLSILLGGQSALLHAQAT--FNMDLLEKNDHLPAVDLQRFNQQAGQPPGAYPVSWQVNG 69 V L + + + A FN L + DL RF PPG Y V +N Sbjct: 28 VRLFVACAFAAQAPLSSAELYFNPRFLADDP-QAVADLSRFENGQELPPGTYRVDIYLNN 86 Query: 70 VTLDARKTVTFRQND-RGQLTPCLKPEDLLQAGVNPAVLSQAPSATSRSCPELNALLPGS 128 + + VTF D + PCL L G+N A +S +C L +++ + Sbjct: 87 GYMA-TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDA 145 Query: 129 TVNFDFAHQRLVMTIPQALMTHRARDNVPSALWDEGISAFQSNYRYSGASQRTREGSTER 188 T D QRL +TIPQA M++RAR +P LWD GI+A NY +SG S + R G Sbjct: 146 TAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSH 205 Query: 189 DNYLMLKSGVNLGAWRLRASNSLTAN-----SDDKPQWTTSGAWLERDLTRWQSELTLGD 243 YL L+SG+N+GAWRLR + + + N S K +W WLERD+ +S LTLGD Sbjct: 206 YAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGD 265 Query: 244 TFTSGDVFDAVQFQGISLASSDAMLPDSQKGFAPTIRGIARTNAQVTVRQNGYVLYQTYV 303 +T GD+FD + F+G LAS D MLPDSQ+GFAP I GIAR AQVT++QNGY +Y + V Sbjct: 266 GYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTV 325 Query: 304 TPGAFVIDDLYPTASSGNLEVAVKESDGEIRRFTQPYASVTSMQREGSLKYNLVAGRYHS 363 PG F I+D+Y +SG+L+V +KE+DG + FT PY+SV +QREG +Y++ AG Y S Sbjct: 326 PPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRS 385 Query: 364 DDASQR-PLMMQLSLMRGFAHNLTLFGGLQSAAQYHNLSLGAGQGLGEAGALSLQLLNAR 422 +A Q P Q +L+ G T++GG Q A +Y + G G+ +G GALS+ + A Sbjct: 386 GNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQAN 445 Query: 423 DR-HQQDPIDGRAWQLQYSKGFDRLGTQLTFTGWRYSHQRYATLSEAFSSPGSDDDLQDS 481 DG++ + Y+K + GT + G+RYS Y ++ S + +++ Sbjct: 446 STLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQ 505 Query: 482 D-----------------NKKATLQITASQSLPYDITLYLSLDQDSYWSGGATQRTANMG 524 D NK+ LQ+T +Q L TLYLS +YW G Sbjct: 506 DGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAG 565 Query: 525 ISSRVHGIAWSLSYSDSRSSHGDEEDDEPHSDKVVTLSLSVPLSHLLPG--------SYA 576 +++ I W+LSYS ++++ D+++ L++++P SH L + A Sbjct: 566 LNTAFEDINWTLSYSLTKNAWQKG------RDQMLALNVNIPFSHWLRSDSKSQWRHASA 619 Query: 577 GYTLTSSRHSVGSQMVSLNGTLLDNHALSYAVSQTRDRQ----NGSSGSLTAGYSSGRGD 632 Y+++ + + + + GTLL+++ LSY+V +GS+G T Y G G+ Sbjct: 620 SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGN 679 Query: 633 LNLGYSHDSQAARLNYGASGGILIHRHGVVFTPEMNGAVVLIDAGGAGGVTLANQKTIAT 692 N+GYSH +L YG SGG+L H +GV +N VVL+ A GA + NQ + T Sbjct: 680 ANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRT 739 Query: 693 NGDGYAVLPFATAYHRNDVSLDSHSLPENVDLANSTVTLVPTEDAVVLARFHTHVGYKAL 752 + GYAVLP+AT Y N V+LD+++L +NVDL N+ +VPT A+V A F VG K L Sbjct: 740 DWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLL 799 Query: 753 FTLQSRGQPLPFGSEVRAKDTNS--IVASEGQVYLAGLAPKGTLYAQWGPGPQQRCSARY 810 TL +PLPFG+ V ++ + S IVA GQVYL+G+ G + +WG C A Y Sbjct: 800 MTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANY 859 Query: 811 DLTPTLAQTPHPLILQQTLSC 831 L P Q + Q + C Sbjct: 860 QLPPESQQQL---LTQLSAEC 877
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.7 bits (103), Expect = 1e-06 Identities = 31/157 (19%), Positives = 59/157 (37%), Gaps = 2/157 (1%) Query: 26 LGVFGLIVAEFLPASLLTPMASSLGVSEGMAGQAVTATALVALVTGLLIATATRNIDRRW 85 L F ++ L SL +A+ TA L + + + + + Sbjct: 22 LSFFSVLNEMVLNVSLPD-IANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 86 VLMFFSVLQIVSSLMVAFADSLAFLL-LGRLLLGIAIGGFWAMSTATAMRLVPAAHVPKA 144 +L+F ++ S++ S LL + R + G F A+ R +P + KA Sbjct: 81 LLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKA 140 Query: 145 LAIIFSAVSVATVVAAPLGSYLGELIGWRNVFILCAI 181 +I S V++ V +G + I W + ++ I Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMI 177
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 25.8 bits (56), Expect = 0.025 Identities = 10/29 (34%), Positives = 19/29 (65%) Query: 52 RRTPWARKEVEAMYLASLDDDAPVEKADP 80 +R WA KEV+A ++ + +D +E+ +P Sbjct: 415 KRLYWASKEVKAQFMRVVQNDKALEEGNP 443
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.006 Identities = 31/128 (24%), Positives = 50/128 (39%), Gaps = 4/128 (3%) Query: 246 VHLWALFGLAAAPSCLIWHKLVLKWGYRQALTRNLLVQALGVILPACSASLLFCVLSALL 305 + L+AL A AP + L ++G R L +L A+ + A + L + ++ Sbjct: 49 LALYALMQFACAP---VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 306 VGFTFMGTVTIALPKAKSLSHQVSFNMIAAMTALYGVGQIAGPLIAGALYQIAASFNPAL 365 G T A M+A +G G +AGP++ G + + P Sbjct: 106 AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHA-PFF 164 Query: 366 YAAALALL 373 AAAL L Sbjct: 165 AAAALNGL 172
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 5e-06 Identities = 81/397 (20%), Positives = 143/397 (36%), Gaps = 32/397 (8%) Query: 11 NLRIISIVVFTCICYLSIGLPLAVLPGYIHYQLGYSTFVA---GIVISLQYISTLISRPH 67 N +I I+ + + IGL + VLPG + L +S V GI+++L + P Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLR-DLVHSNDVTAHYGILLALYALMQFACAPV 62 Query: 68 AGRYTDIWGPKKVVSLGIVCCLLSGAFTLLAVVLQATPMLAIAALLAGRVFLGV-GESFT 126 G +D +G + V+ + + + ++ P L + L GR+ G+ G + Sbjct: 63 LGALSDRFGRRPVLLVSLA------GAAVDYAIMATAPFLWV--LYIGRIVAGITGATGA 114 Query: 127 ATGATLWGIKTVGAIHTSRVISWNGVATYVAMAVGAPLGVTLNHYFGISGF--ATVVVLV 184 GA + I +R + M G LG + + + F A + + Sbjct: 115 VAGAYIADITDGDE--RARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 185 AAIGLLF-------ARTRQDVKVNAGARAPFH-AVVRKIWPYGLGLAFGTVGFGVIATFI 236 + F R + A F A + + + F G + + Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 237 TLYFAAHSWQ----GAAFTLSLFSVGFICVRLVLGNTIT-RFGGVPVSLACFIIESLGLL 291 + F + +L+ F + + ++ + R G + I + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 292 LIWLAPSAWMAGVGAFLTGSGFSLVFPALGVEAVKQVEEQNQGTALGTYSAFLDLALGLT 351 L+ A WMA L SG + PAL +QV+E+ QG G+ +A L + Sbjct: 293 LLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT-SIV 350 Query: 352 GPLAGWVAGFYDLATLYLLAAIVVALAFLLIFRVHRQ 388 GPL + T A I A +LL R+ Sbjct: 351 GPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 6e-04 Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 81 YLEDLFVDPAFRGQGIARTMIKSLQSEGADKGWSRLYWHTRRDN-PARHLY 130 +ED+ V +R +G+ ++ + + L T+ N A H Y Sbjct: 91 LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFY 141
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 7e-04 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 92 RADVAKLLVHQNVRRQGIAQALMSELERIARRERKTVLVLDTAT-GSGAEQFYARCGWEK 150 A + + V ++ R++G+ AL+ + A+ L+L+T A FYA+ + Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF-I 147 Query: 151 VGEIPR--YALMPDGEMTATSLFYKF 174 +G + Y+ P A +YKF Sbjct: 148 IGAVDTMLYSNFPTANEIAIFWYYKF 173
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.8 bits (80), Expect = 3e-04 Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 3/71 (4%) Query: 22 GRGKVADYIPALASVSGDKLGI-AISTVDGQHFAAGDAHERFSIQSISKVL--SLVVAMN 78 + + I S ++G+ + G+ A A ERF + S KV+ V+A Sbjct: 21 ASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80 Query: 79 HYQEEEIWQRV 89 +E++ +++ Sbjct: 81 DAGDEQLERKI 91
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 7e-06 Identities = 14/73 (19%), Positives = 25/73 (34%), Gaps = 1/73 (1%) Query: 80 IDPQHRGQQLGEKLLAALEAKARQRDCHTLRLETGIHQHAAIALYTRNGYQTRCAFAPYQ 139 + +R + +G LL A++ L LET +A Y ++ + A Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF-IIGAVDTML 155 Query: 140 PDPLSVFMEKPLF 152 E +F Sbjct: 156 YSNFPTANEIAIF 168
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.0 bits (109), Expect = 2e-07 Identities = 46/237 (19%), Positives = 89/237 (37%), Gaps = 14/237 (5%) Query: 7 RSTIALLASSLLLTIGRGATLPFMTIYLTRRFQLEVDVI---GYALSLALVVGVLFSMGF 63 R I +L++ L +G G +P + L R DV G L+L ++ + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADRFDKKRYMVWSVLVFILGFSAIPLVNNAPLVVIFFA--LINCAYSVFSTVLKAWF 121 G L+DRF ++ ++ S+ + ++ ++ AP + + + ++ V A+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYA---IMATAPFLWVLYIGRIVAGITGATGAVAGAYI 120 Query: 122 ADRLTAEKKARIFSLNYTILNIGWTVGPPIGTLLVMHSINLPFWLAAACAAFPLVFIQLF 181 AD +++AR F G GP +G L+ S + PF+ AAA + Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180 Query: 182 L----QRDGAAAAQPGAAPWSPSVLLRD-RALLWFTCSGLLASFVGGAFASCLSQYV 233 L + + + P + R + + VG A+ + Sbjct: 181 LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG 237 Score = 39.4 bits (92), Expect = 2e-05 Identities = 26/158 (16%), Positives = 62/158 (39%), Gaps = 2/158 (1%) Query: 4 TLRRSTIALLASSLLLTIGRGATLPFMTIYLTRRFQLEVDVIGYALSLALVVGVLF-SMG 62 AL+A ++ + I+ RF + IG +L+ ++ L +M Sbjct: 207 RGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMI 266 Query: 63 FGILADRFDKKRYMVWSVLVFILGFSAIPLVNNAPLVVIFFALINCAYSVFSTVLKAWFA 122 G +A R ++R ++ ++ G+ + + L+ + L+A + Sbjct: 267 TGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLS 325 Query: 123 DRLTAEKKARIFSLNYTILNIGWTVGPPIGTLLVMHSI 160 ++ E++ ++ + ++ VGP + T + SI Sbjct: 326 RQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 27.7 bits (61), Expect = 0.021 Identities = 14/32 (43%), Positives = 22/32 (68%), Gaps = 1/32 (3%) Query: 19 EQLAEMAGLSVRTIQRIENGER-PGLETLSAL 49 E+ + G+SV + QR++NGER G+E L+ L Sbjct: 23 EETGKHKGVSVISYQRVKNGERNKGIEALNRL 54
>PF05211#Neuraminyllactose-binding hemagglutinin Length = 260 Score = 27.7 bits (61), Expect = 0.039 Identities = 15/55 (27%), Positives = 28/55 (50%), Gaps = 7/55 (12%) Query: 43 LSLAIGVGELRCVIGPNGAGKTTLMDVITGKTRPQSGKALYDQSVDLTTLDPVAI 97 L + G+ ++ V+ P G K T+++ P SG++L ++DL+ LD Sbjct: 145 LLFSTGLDKMEGVLIPAGFVKVTILE-------PMSGESLDSFTMDLSELDIQEK 192
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 58/271 (21%), Positives = 104/271 (38%), Gaps = 37/271 (13%) Query: 12 TETGIVFSSISLFAIIFQPVFGLMSDKLGLRKHLLWTITVLLILFA-PFFIFVFSPLLQM 70 GI+ + +L PV G +SD+ G R LL V L A + I +P L + Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLL----VSLAGAAVDYAIMATAPFLWV 98 Query: 71 NIIAGSLVGGIYLGIVFSSGSGAVEAYIERVSRANRFEYGKVRVAGCVGWALCAS--ITG 128 + G +V GI G + + + RA F + ++ C G+ + A + G Sbjct: 99 -LYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGF----MSACFGFGMVAGPVLGG 152 Query: 129 VLFSIDPNITFWIASGFALVLGLLLWLSRPESSNS------AQVIEALGANRQAFSLRTA 182 ++ P+ F+ A+ + L PES + + L + R A + Sbjct: 153 LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 183 AELLRMPRFWGFIVYVVG--VASVYDVFDQQFANFFKSFFASPQRGTEVFGFVTTGGELL 240 A L+ FI+ +VG A+++ +F + ++ G +L Sbjct: 213 AALM----AVFFIMQLVGQVPAALWVIFGEDRFHW----------DATTIGISLAAFGIL 258 Query: 241 NALI-MFCAPAIVNRIGAKNALLTAGMIMSV 270 ++L + R+G + AL+ GMI Sbjct: 259 HSLAQAMITGPVAARLGERRALM-LGMIADG 288
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 437 bits (1126), Expect = e-159 Identities = 285/286 (99%), Positives = 285/286 (99%) Query: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKQSESQLSGRVGMIEMDLASGRTLTAWRADE 60 MRYIRLCIISLLATLPLAVHASPQPLEQIK SESQLSGRVGMIEMDLASGRTLTAWRADE Sbjct: 1 MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE 60 Query: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA Sbjct: 61 RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA 120 Query: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA Sbjct: 121 AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA 180 Query: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG 240 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG Sbjct: 181 SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG 240 Query: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 286 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR Sbjct: 241 IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR 286
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 53.7 bits (129), Expect = 5e-10 Identities = 62/295 (21%), Positives = 108/295 (36%), Gaps = 15/295 (5%) Query: 55 VQPILPVLSNEFGVSPASSS---ISLSISTAMLAVGLLFTGPLSDAIGRKPVMVTALLLA 111 + P+LP L + S ++ I L++ M G LSD GR+PV++ +L A Sbjct: 24 IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83 Query: 112 ACCSLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSI 171 A + + I R + G++ AV Y+++ A G + Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 172 GGMSGRLLTGVFTDFFGWRVALAAISGFALAAAIMFWRILPES--RHFRPTSLRPKTLLI 229 G ++G +L G+ F A + + +LPES RP L Sbjct: 143 GMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLA 201 Query: 230 NFRLHWRDRGLPLLFIEGFLLM---GAFVTLFN-YIGYRLMMSPWSLSQAVVGLLSVAYL 285 +FR + L F++ L+ + R ++ ++ + L Sbjct: 202 SFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSL 261 Query: 286 TGTWSSPKAGAMTVRFG-RGPVMLGFTAVMLCGLLLTLFSSLWLIFIGMLLFSAG 339 G + R G R +MLG A +LL + W+ F M+L ++G Sbjct: 262 AQAMI---TGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG 313
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.002 Identities = 21/125 (16%), Positives = 39/125 (31%), Gaps = 9/125 (7%) Query: 16 SSAAFAADAVSTTQAPAATHSTAAKTTHHKKHHKA--AAKPAAEQKAQAAKKHKKAEAKP 73 A A + A A + A T ++ + + + A K+ +AK Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 74 AAAQKAQAAKKHKKVAAKPAAPQKAQAAKKHHKAAAKPAAQKAQAAKKHHKTTKHQAAKP 133 + + K +V+ K + Q A+PA + ++ Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQ-------AEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 134 TAQPA 138 T QPA Sbjct: 1168 TEQPA 1172 Score = 29.6 bits (66), Expect = 0.005 Identities = 16/117 (13%), Positives = 31/117 (26%), Gaps = 7/117 (5%) Query: 23 DAVSTTQAPAATHSTAAKTTHHKKHHKAAAKPAAEQKAQAAKKHKKAEAKPAAAQKAQAA 82 V TT + A + + A A A P+ + A Sbjct: 990 QTVDTTNITTPNNIQADVP-------SVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 83 KKHKKVAAKPAAPQKAQAAKKHHKAAAKPAAQKAQAAKKHHKTTKHQAAKPTAQPAA 139 ++ Q A ++ AK A +A + ++ + + Q Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 109 bits (273), Expect = 5e-30 Identities = 27/234 (11%), Positives = 70/234 (29%), Gaps = 47/234 (20%) Query: 26 LSAKDIKTLFFGHDDRKAVNRPEESPWDAIGQLET---ASGNLCTATLISPHLALTAGHC 82 L ++ + ++DR + + + ++ + + ++ LT H Sbjct: 61 LEQREHANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHV 120 Query: 83 LLTPPRGKPDKAVALRFI------SRKGNWVYE---IHGIDGRVDPSLGRRLKADGDGWI 133 + AL+ N + I G D ++ + + Sbjct: 121 V----DATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVK-FSPNEQN-- 173 Query: 134 VPSAAAPSDFGLIVLRYAPSGITPIPLFPGSKADLTAALKAADRKVTQSGYPEDH-LDNL 192 ++ + P + A ++ +T +GYP D + + Sbjct: 174 ---------------KHIGEVVKPATM-------SNNAETQVNQNITVTGYPGDKPVATM 211 Query: 193 YSHQDCIVTGWAQTSVLSHQCDTLPGDSGSPLLLKTEDGWQVIAVQSSAPGPQD 246 + + + + + + T G+SGSP+ + +VI + + Sbjct: 212 WESK--GKITYLKGEAMQYDLSTTGGNSGSPVF---NEKNEVIGIHWGGVPNEF 260
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 36.2 bits (83), Expect = 6e-05 Identities = 51/254 (20%), Positives = 93/254 (36%), Gaps = 28/254 (11%) Query: 9 ILITGAGRRIGLALAHHFLQQRQPVIVSYRTPYPAIDGLREAGALCLQADFSSDDGILTF 68 ITGA + IG A+A Q + P + A A+ D + Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD--VRD 68 Query: 69 AEAVKSHTNGLRAIIHNASDWMAEKPGVPLSAVINRMMQIHVHAPYLLNHALEALLRGHG 128 + A+ T + + D + GV +I+ + A + +N + Sbjct: 69 SAAIDEITARIEREMGPI-DILVNVAGVLRPGLIHSLSDEEWEATFSVN-STGVFNASRS 126 Query: 129 HAASDIIHITDYVVERGSDKH-------IAYAASKAALDNMTRSFARKLAPE-VKVNAIA 180 + + + +V GS+ AYA+SKAA T+ +LA ++ N ++ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 181 P---------SLIMFNEGDDEAYR----QQALDKSLMKIAPGEKEISDLIDYLFTSR--Y 225 P SL G ++ + L K+A +I+D + +L + + + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK-PSDIADAVLFLVSGQAGH 245 Query: 226 VTGRSFAVDGGRPL 239 +T + VDGG L Sbjct: 246 ITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.4 bits (162), Expect = 7e-15 Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 1/117 (0%) Query: 3 KIVFVEDDPEVGTLIAAYLGKHDMDVVVEPRGDRAEEVIAREKPDLVLLDIMLPGKDGMT 62 I+ +DD + T++ L + DV + IA DLV+ D+++P ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 LCRDLRGQWQG-PIVLLTSLDSDMNHILSLEMGASDYILKTTPPAVLLARLRLHLRQ 118 L ++ P++++++ ++ M I + E GA DY+ K L+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 31.7 bits (72), Expect = 0.007 Identities = 25/134 (18%), Positives = 52/134 (38%), Gaps = 13/134 (9%) Query: 316 AQSQALLAKPELAQNPELYQQALTETLFNALPILLKGNPSVTISPLS-WRNAKGESTLNL 374 +Q + K + EL +++L A+ I+ ++ P R A + LN Sbjct: 74 MMAQEFIQKGGIDYARELLEKSLGTQ--KAVDIINNLGSALQSRPFEFVRRADPANILNF 131 Query: 375 SVLLKDPAQVTAPPQTLAESLDRVVQSLDGKVV--IPVDMATEFMTKIAGLEGYQPADAA 432 ++ PQT+A L + ++ +P ++ T +IA ++ P Sbjct: 132 ---IQQEH-----PQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVR 183 Query: 433 KLADQQVKGLAAMG 446 ++ K LA++ Sbjct: 184 EVERVLEKKLASLS 197
>PF01206#SirA family protein Length = 76 Score = 92.9 bits (231), Expect = 4e-29 Identities = 16/71 (22%), Positives = 38/71 (53%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPSLQKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + ++ GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.007 Identities = 37/161 (22%), Positives = 65/161 (40%), Gaps = 32/161 (19%) Query: 59 ILSWL--SFSLTFFIRPIGGVIFAHIGDRIGRKKTLVLTLSLMGSATVAIGLLPTYEMVG 116 +W+ +F LTF IG ++ + D++G K+ L+ + + +V VG Sbjct: 50 STNWVNTAFMLTF---SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI-------GFVG 99 Query: 117 LWAPALLITLRIIQGMGIGGEWGGALLAY---EYAPEKRK----GFFGSIPQAGVTIGML 169 +LLI R IQ G G AL+ Y P++ + G GSI G +G Sbjct: 100 HSFFSLLIMARFIQ--GAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPA 157 Query: 170 MATFIVSLMTLFDEAQFLAWGWRIPFLLSSVLVFLGLWIRK 210 + I A ++ W + L+ + + ++ K Sbjct: 158 IGGMI---------AHYIHWSYL--LLIPMITIITVPFLMK 187
>PF06291#Lambda prophage Bor protein Length = 102 Score = 27.3 bits (60), Expect = 0.002 Identities = 9/17 (52%), Positives = 13/17 (76%) Query: 1 MKKLLLAMAASMLLAGC 17 MKK+L + A +ML+ GC Sbjct: 6 MKKMLFSAALAMLITGC 22
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.9 bits (142), Expect = 3e-13 Identities = 28/166 (16%), Positives = 58/166 (34%), Gaps = 12/166 (7%) Query: 1 MRADARKNYDLLIEVARDVFVEQGAEA-SLRDIARRAGVGMGTLYRHFPNRDSLLEAVLR 59 + +A++ +++VA +F +QG + SL +IA+ AGV G +Y HF ++ L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 60 SRFAALTARAESLL------LAADPAAALLEWLAESVAFTHQHRGIIAPLMSAIDDPESA 113 + + + L+ L +V + + E A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 114 L-----HSACVALRAAGTSLLTRAQQAGLARPDLSGEELFDLIAAL 154 + + C+ L +A + DL ++ Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 40.2 bits (94), Expect = 6e-06 Identities = 29/129 (22%), Positives = 47/129 (36%), Gaps = 19/129 (14%) Query: 6 TVLVFGATGQQGGSVARALLHRGWRVRALVRDPFSAG---------AAALAARGAELVVG 56 LV GA G G V++ LL G +V + D + LA G + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGI--DNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 57 TFEDRAAMRSAMA--GVDGVF------SVQPSSPGGTVTDEQEVRYGITIADLAVECGVK 108 DR M A + VF +V+ S + + + I + ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 109 HLVYSSGSA 117 HL+Y+S S+ Sbjct: 120 HLLYASSSS 128
>PF05043#Transcriptional activator Length = 493 Score = 33.8 bits (77), Expect = 4e-04 Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 1 MNKIIENDFSRIDLNLLTVLMVLYREGSVTRTAEVLHLGQPAISGALKRLREMFDDPLFV 60 M ++ R L LL +L R + AE+L+ + A+ L ++ F D +F Sbjct: 1 MRDLLSKKSHR-QLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFH 59 Query: 61 RSARGM 66 S G+ Sbjct: 60 SSTNGI 65
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 6e-29 Identities = 67/258 (25%), Positives = 110/258 (42%), Gaps = 16/258 (6%) Query: 3 KIALITGANRGLGRQTALDIARQGGDVIVTYRGSLEQAEAVVADIRALGRKAIALPLDMA 62 KIA ITGA +G+G A +A QG + + E+ E VV+ ++A R A A P D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 63 QTASFPAFADSLGSALASVWGRATFDHLINNAGHGEFAPLAETREAQFDGLFNVHVKGVF 122 +A+ + + D L+N AG + + +++ F+V+ GVF Sbjct: 68 DSAAIDEITARIEREMGP------IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 123 FLVQTLLPLLAD--GGRIVNFSSGLTRVSYPGFSAYAAAKAAVEMLSVYMARELGGRGIT 180 +++ + D G IV S V +AYA++KAA M + + EL I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 181 VNTIAPGAIATDFGGGL-VRDDAEVN------AQFAAMTALGRVGVPEDIGPMIASLLRD 233 N ++PG+ TD L ++ F L ++ P DI + L+ Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 234 DNRWVTAQRIEVSGGQTI 251 +T + V GG T+ Sbjct: 242 QAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 6e-08 Identities = 19/123 (15%), Positives = 47/123 (38%), Gaps = 2/123 (1%) Query: 6 PGRTPGRPRQFDAEQAIETAQRLFHARGYDAVSVADLTHAFGINPPSFYAAFGNKLGLYT 65 +T ++ + ++ A RLF +G + S+ ++ A G+ + Y F +K L++ Sbjct: 2 ARKTKQEAQE-TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 66 RVLQR-YSQTGAIPIDALLRDDQPVAASLIAVLQEAARRYVADPAAAGCLVLEGVHCQDA 124 + + S G + ++ + + L +L V + + + C+ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 125 DAR 127 Sbjct: 121 GEM 123
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 80.9 bits (199), Expect = 2e-20 Identities = 65/249 (26%), Positives = 111/249 (44%), Gaps = 24/249 (9%) Query: 7 KSVLVLGGSRGIGAAIVRRFVADGASVVFSYSGSPEAAERLAAETGSTA-----VQADSA 61 K + G ++GIG A+ R + GA + + +PE E++ + + A AD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 62 DRDAVISLV----RDSGPLDVLVVNAGIALFGDALEQDSDAIDRLFRINIHAPYHASVEA 117 D A+ + R+ GP+D+LV AG+ G + + F +N ++AS Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 ARRMP--EGGRIIVIGSVNGDRMPLPGMAAYALSKSALQGLARGLARDFGPRGITVNVVQ 175 ++ M G I+ +GS N +P MAAYA SK+A + L + I N+V Sbjct: 128 SKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 176 PGPIDTDA--------NPGNGPMKELMHSF---MAIKRHGRPEEVAGMVAWLAGPEASFV 224 PG +TD N +K + +F + +K+ +P ++A V +L +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 225 TGAMHTIDG 233 T +DG Sbjct: 247 TMHNLCVDG 255
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.015 Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 17/105 (16%) Query: 580 GKRVVGQEAALSAIARRL-RAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGG 638 G +VG+ AA+ I R L R +T LT ++ G SGTGK A AL D Sbjct: 136 GMPLVGRSAAMQEIYRVLARLMQTDLT--------LMITGESGTGKELVARALHDYGKRR 187 Query: 639 EKALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRP 683 + IN++ S+L G + G T A + Sbjct: 188 NGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRST 224
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 92.7 bits (230), Expect = 1e-22 Identities = 45/146 (30%), Positives = 63/146 (43%), Gaps = 12/146 (8%) Query: 416 PPPPPRPVQRVAPDVIRLDSMSLFDTGKWVLKPGSTKRL--VSSLMDIKARPGWLIVVAG 473 P P P V L S LF+ K LKP L + S + +VV G Sbjct: 200 VAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLG 259 Query: 474 HTDSVGEEKANQLLSLKRAESVRDWMRDTGDVPDSCFAVQGYGESRPIATNDT------- 526 +TD +G + NQ LS +RA+SV D++ G +P + +G GES P+ N Sbjct: 260 YTDRIGSDAYNQGLSERRAQSVVDYLISKG-IPADKISARGMGESNPVTGNTCDNVKQRA 318 Query: 527 --PEGRALNRRVEISLVPQVDACRLP 550 + A +RRVEI + D P Sbjct: 319 ALIDCLAPDRRVEIEVKGIKDVVTQP 344
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.2 bits (179), Expect = 2e-17 Identities = 64/254 (25%), Positives = 102/254 (40%), Gaps = 15/254 (5%) Query: 6 KIALVTGGSRGLGRATVEALAQRGVNVVLTYKTRLAEANEVVTRVEALGARAIALPFSAG 65 KIA +TG ++G+G A LA +G ++ + +VV+ ++A A A P Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 66 EIDTFDAFVSAFQGALTELGADKFDYLVNNAGNASGMGFLNATEAEFDALYCIHVKSVFF 125 D D+ A E D LVN AG + ++ E++A + ++ VF Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 126 LSQKLLPLLAD--GGRIVNVSSGLTRIVMANRAPYAIMKSAVETLTRYMAFELGSRGITV 183 S+ + + D G IV V S + + A YA K+A T+ + EL I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 184 NCVAPGAIATDFSGGVVRDNPQVAQAVANMTA-------LGRPGLPEDIGPMIASLLSDD 236 N V+PG+ TD + D Q + L + P DI + L+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 237 HRWVNAQRIEVSGG 250 + + V GG Sbjct: 243 AGHITMHNLCVDGG 256
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 31.2 bits (70), Expect = 0.005 Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 10/90 (11%) Query: 11 VRIVERGSFSAAAADLGVSRPVATAAIKALEVSLGARLLHRTTRHVRPTAEGSLYYQRCV 70 +RIV SAAAA L P+A A+ V+ + + + A+ + + Sbjct: 5 LRIV-----SAAAAALLAVAPIAAT---AMPVNAATTINADSAINANTNAKYDVDVTPSI 56 Query: 71 SILAALEEANRSAG--GSISGTIRVDVAGN 98 S +AA+ +++ GS++G+I G Sbjct: 57 SAIAAVAKSDTMPAIPGSLTGSISASYNGK 86
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 21/113 (18%), Positives = 45/113 (39%), Gaps = 2/113 (1%) Query: 76 RKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVP 135 ++ LL G+ S + S F + ++ R + G F ++ R +P+ Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 136 RALAIFNGGNALATVVAAPLGSYLGATVGWRGAFLYLVPLAVLAFVWQCISLP 188 +A + A+ V +G + + W ++L L+P+ + V + L Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPFLMKLL 189
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 308 bits (790), Expect = e-101 Identities = 112/377 (29%), Positives = 172/377 (45%), Gaps = 38/377 (10%) Query: 174 VLTGAVAMLRSTVRMGRQLQTMTSQDTSAFSQILAVGPKMRHVVEQARKLAMLSAPLLIV 233 LT + ++ + ++ + D+ ++ M+ + +L L+I Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Query: 234 GDTGTGKDLLAHACHLASPRAGKPYLALNCGSIPEDAVESELFG-------DALQGKKGF 286 G++GTGK+L+A A H R P++A+N +IP D +ESELFG A G Sbjct: 167 GESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGR 226 Query: 287 FEQANGGSVLLDEIGEMSPRMQTKLLRFLNDGTFRRVGEDHEVHVDVRVICATQKNLIEL 346 FEQA GG++ LDEIG+M QT+LLR L G + VG + DVR++ AT K+L + Sbjct: 227 FEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQS 286 Query: 347 VQKGLFREDLYYRLNVLTLYLPPLRDCPQDIMPLTELFVARFADEQGIPRPKLSADLSTV 406 + +GLFREDLYYRLNV+ L LPPLRD +DI L FV + E G+ + + + Sbjct: 287 INQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALEL 345 Query: 407 LTRYSWPGNVRQLKNAVYRALTQLEGFELRPQDILLP---------------DHDVASLP 451 + + WPGNVR+L+N V R + + I S+ Sbjct: 346 MKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSIS 405 Query: 452 VGEEAM--------------EGSLDDITRRFERSVLTQ-LYRSYPSTRKLAKRLGVSHTA 496 E G D + E ++ L + + K A LG++ Sbjct: 406 QAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNT 465 Query: 497 IANKLREYGLSQKKGDE 513 + K+RE G+S + Sbjct: 466 LRKKIRELGVSVYRSSR 482
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 344 bits (884), Expect = e-118 Identities = 127/346 (36%), Positives = 183/346 (52%), Gaps = 26/346 (7%) Query: 7 AQYKDNLLGEANSFLEVLEQVSRLAPLDKPVLVIGERGTGKELIANRLHYLSSRWQGPFI 66 +Q L+G + + E+ ++RL D +++ GE GTGKEL+A LH R GPF+ Sbjct: 133 SQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFV 192 Query: 67 SLNCAALNDNLLDSELFGHEAGAFTGASKRHPGRFERADGGTLFLDELATAPMLVQEKLL 126 ++N AA+ +L++SELFGHE GAFTGA R GRFE+A+GGTLFLDE+ PM Q +LL Sbjct: 193 AINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLL 252 Query: 127 RVIEYGELERVGGSQPLQVNVRLVCATNADLPQMVEEGHFRADLLDRLAFDVVQLPPLRD 186 RV++ GE VGG P++ +VR+V ATN DL Q + +G FR DL RL ++LPPLRD Sbjct: 253 RVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRD 312 Query: 187 RQSDIMLLANQFAIQMCRELGLPLFPGFSERATATLLGYRWPGNIRELKNVVERSVYRHG 246 R DI L F Q +E F + A + + WPGN+REL+N+V R + Sbjct: 313 RAEDIPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYP 370 Query: 247 DSE--------HELDAIIINPFRQSPG---------------SPPEAAPGDELPALPLDL 283 I +P ++ A+ GD LP L Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGL-Y 429 Query: 284 RDFQLQQEKRLLQRSLEQAKYHQKQAAELLGLTYHQLRALLKKHQL 329 + E L+ +L + +Q +AA+LLGL + LR +++ + Sbjct: 430 DRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 88.8 bits (220), Expect = 4e-21 Identities = 81/415 (19%), Positives = 161/415 (38%), Gaps = 34/415 (8%) Query: 28 FWLFAQSVINVVPAMISSLDISLETLTLAVSLS-----------ALFSGCFVVASGGLAD 76 WL S +V+ M+ L++SL + + L G L+D Sbjct: 17 IWLCILSFFSVLNEMV--LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 77 KFGRMRMTTIGLGLSIVGSAMLVVAQGP-GLFLAGRVLQGLSAACIMPATLALIKTWYEG 135 + G R+ G+ ++ GS + V L + R +QG AA + ++ + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 136 RARQRAVSFWVIGSWGGSGLCSFVGGAIATGLGWRWIFVFSIAVALLALFLLRGTPESRS 195 R +A G G+ +GG IA + W ++ + + + FL++ + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKK--E 192 Query: 196 ASASQHKLDVGGLLSLIVALVLVNLFISKGHGWGWSSPLSLTMLAGALAAGTIFIRNGMR 255 H D+ G++ + V +V LF + + + L+ L IF+++ +R Sbjct: 193 VRIKGH-FDIKGIILMSVGIVFFMLF-TTSYSISFLIVSVLSFL--------IFVKH-IR 241 Query: 256 KGEAALIDFALFRNRAYGAAVLSNFLLNGAI-GTMMIASIWLQQGHHLTPLESGMMTLGY 314 K +D L +N + VL ++ G + G + + ++ H L+ E G + + + Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII-F 300 Query: 315 LVTVLAMIR--VGEKLLQRYGARLPMMAGPVLTAIAIALISCTFLEKALYIGVVFASNVL 372 T+ +I +G L+ R G + G +++ L + LE + + + Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSF-LTASFLLETTSWF-MTIIIVFV 358 Query: 373 FGLGLGCYATPSTDTAVANAPENKIGVASGIYKMGSSLGGAMGIAVTASLFALFL 427 G GL T + ++ + + G + S L GIA+ L ++ L Sbjct: 359 LG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.5 bits (113), Expect = 3e-08 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 11/83 (13%) Query: 2 MRIFLTGASGFIGSRILPALQASGHKVIGL---------ARSESTAQALKAAGAEVHRGT 52 M+ +TGA+GFIG + L +GH+V+G+ + ++ + L G + H+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 53 LDAPESL--LAGVGNADAVIHTA 73 L E + L G+ + V + Sbjct: 61 LADREGMTDLFASGHFERVFISP 83
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.3 bits (234), Expect = 3e-25 Identities = 62/239 (25%), Positives = 102/239 (42%), Gaps = 22/239 (9%) Query: 13 RIILVTGASDGIGREAALTYARYSASVILLGRNDDKLRTVAQEIEREGGIPPRWFTLDLL 72 +I +TGA+ GIG A T A A + + N +KL V ++ E F D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA-FPADV- 66 Query: 73 TCTPQACQQLAQQISMHYPRLDGVLHNAGLLGDICPMEEQKPEVWQQVMQVNVNGTFMLT 132 A ++ +I +D +++ AG+L + E W+ VN G F + Sbjct: 67 -RDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 133 QALLPLLLRSESGSLVFTSSSVGRQGRANWGAYAVSKFATEGMMQVLADEYQSRHLRVNC 192 +++ ++ SGS+V S+ R + AYA SK A + L E ++R N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 193 INPGGTRTGMRASAFPTED-----------------PL-KLKTPADIMPVYLWLMGDDS 233 ++PG T T M+ S + E+ PL KL P+DI L+L+ + Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.029 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 4/44 (9%) Query: 11 VRRQPLLQEVAFSVAPG----EVLTLMGPSGSGKSTLFAWMIGA 50 V + L+ VA + PG + L G G GKSTL ++G Sbjct: 576 VGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 4e-05 Identities = 25/118 (21%), Positives = 48/118 (40%), Gaps = 1/118 (0%) Query: 65 ALMFGYFIGSLTGGFIGDYLGRRKAFRLNLLIVGISACVATFVPNMY-WLIFCRCLMGCG 123 A M + IG+ G + D LG ++ ++I + + + + LI R + G G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 124 MGALIMIGYASFTEFIPPAVRGKWSARLSFVGNWSPMLSAAIGIVVIAFLSWRIMFLL 181 A + +IP RGK + + + AIG ++ ++ W + L+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.007 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Query: 25 LKELGWTDNSTTATFSAITTAGMFLGALGG---GIIGDKIGRKNAFILYEAIHIIAMVVG 81 L ++ N A+ + + TA M ++G G + D++G K + I+ V+G Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 82 AFSPNMTF-LIACRFVMGVGLGALLVTLFAGFTEYMPGRNRG 122 + LI RF+ G G A + Y+P NRG Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.8 bits (111), Expect = 9e-08 Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 1/142 (0%) Query: 40 LSALAADFHQTESGVGLAVTAYGWVGALAALLSGAMPARISRKALLVGLMLILAFSCLAA 99 L +A DF++ + TA+ ++ + G + ++ K LL+ ++I F + Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 100 TRSYSMFA-LMSARMIGALAHGAFWALIGIVAAQLVPPHRLGLATAIIFGGVSAASVVGV 158 +S F+ L+ AR I AF AL+ +V A+ +P G A +I V+ VG Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 159 PLASFIATLAGWRLAFMSMALL 180 + IA W + + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMIT 178
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 122 bits (306), Expect = 8e-36 Identities = 70/254 (27%), Positives = 120/254 (47%), Gaps = 10/254 (3%) Query: 2 SKKLADKVALVTGGSAGIGLASAKALAEQGAKVY---ITGRRQEELDAAVRFIGPAARGI 58 +K + K+A +TG + GIG A A+ LA QGA + + E++ ++++ A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 59 RADAAVLSDLDAVFATIAEESGRLDVLFANAGGGDMLPLSAITEAHVDRIFATNVRGVVF 118 AD + +D + A I E G +D+L AG + ++++ + F+ N GV Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 119 TVQKALPLLAD--GASVILTGSTAAVKGTANFSIYSASKAAVRSLARSWALEVSDRGIRI 176 + + D S++ GS A + + Y++SKAA + LE+++ IR Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 177 NVVSPGPVRTPGLGGLVAEADRQ-----GLFDALAAGVPLGRLGEPEEIGRTVVFLASDE 231 N+VSPG T L A+ + G + G+PL +L +P +I V+FL S + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 232 SSFINAAEIYVDGG 245 + I + VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 26.6 bits (58), Expect = 0.045 Identities = 17/64 (26%), Positives = 26/64 (40%) Query: 46 VEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFMNWKSLLAIAVGVFVSWLGGRGVSL 105 V Q + L IG + + LPPS ++ N ++ A VS LG ++L Sbjct: 171 VTVQRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTL 230 Query: 106 MGSQ 109 G Sbjct: 231 DGGH 234
>BORPETOXINB#Bordetella pertussis toxin B subunit signature. Length = 226 Score = 25.4 bits (55), Expect = 0.026 Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 3/38 (7%) Query: 4 LLAILPLALAGCTQPQPTAPTKTIGMPNPAAVYCQQSG 41 LL++LPLAL G + + P I P Q G Sbjct: 11 LLSVLPLALLGSHVARASTPGIVI---PPQEQITQHGG 45
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.011 Identities = 26/137 (18%), Positives = 43/137 (31%), Gaps = 12/137 (8%) Query: 110 SHRIFWDYAFAGGSLLATFSQGIVVGAFINGFAVADRRFAGSTLDWLTPFNLFCGLGLVV 169 +++ +W G + G A S + GL L Sbjct: 8 ANKYYWYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLM----------GLVLTH 57 Query: 170 AYLLLGTTWLIMKSEGALQQRMRELTRKVLLALMAVIAVVSVWTPLGWRYVAERWFTLPN 229 AY +K Q +R L V++ ++ +A S+W L + FTLP Sbjct: 58 AYRSFIKRQGWLKL-NMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPL 116 Query: 230 FF-WFVPVPILVLALSL 245 V ++ SL Sbjct: 117 ALSIIFNVVVVTFMWSL 133
>PF03309#Bvg accessory factor Length = 271 Score = 27.4 bits (61), Expect = 0.003 Identities = 13/61 (21%), Positives = 22/61 (36%), Gaps = 5/61 (8%) Query: 2 VVPVI---LLKTVKKLLKQVVKVVSTAAGTLKM-IRSVRPKRVKKADRIATAVAASPIIP 57 VP + + +++ V V+ + + PK V ADRI +AA Sbjct: 66 TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVG-ADRIVNCLAAYHKYG 124 Query: 58 D 58 Sbjct: 125 T 125
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 4e-16 Identities = 31/167 (18%), Positives = 53/167 (31%), Gaps = 1/167 (0%) Query: 3 DRDAALDKAMTLFWQHGYEATSLADLVEATGAKAPTLYAEFVNKEGLFRAVLDRYISRFA 62 R LD A+ LF Q G +TSL ++ +A G +Y F +K LF + + S Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 63 AKHEAVLFAEGKSVDRALRDYFTAVATCFTSKETPAGCFIINTSPALAASS-TDIANTIK 121 LR+ V ++E I + + Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 122 SRHAMQEQALTQFLQQRQAQGELPAGRDVAQLAQFLNCVLQGMSISA 168 + + Q L+ LPA + A + + G+ + Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.1 bits (62), Expect = 0.027 Identities = 33/130 (25%), Positives = 45/130 (34%), Gaps = 21/130 (16%) Query: 16 GCAGLREQPAPVEEAKPQPQQPAQPQPTVPTVPAVPSVPAQPGPIEHQDQQSGQPAPRVR 75 G + PAP +P PQ QP P P P P P + +Q PAP Sbjct: 561 SLVGAKAPPAPKPAPQPGPQPGPQP-------PQPPQPPQPPQPPQPPQRQPEAPAP--- 610 Query: 76 HYDWNGAVQPLVGQMLQA---SGVNAGSILLVDSVNNRTNGSLNAGEATTALRSALAGNG 132 QP G+ L A + VN G + L ++ + +L+ L G Sbjct: 611 --------QPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAW 662 Query: 133 KFTLVSAQQL 142 QQL Sbjct: 663 GRGFAQRQQL 672
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.7 bits (61), Expect = 0.005 Identities = 16/48 (33%), Positives = 25/48 (52%) Query: 10 KIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPD 57 ++ G Q + QEE+ N F+E L ++ L +E+F TEI D Sbjct: 380 QLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDNLSEKEKEKFRTEIKD 427
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 156 bits (395), Expect = 4e-49 Identities = 91/250 (36%), Positives = 136/250 (54%), Gaps = 13/250 (5%) Query: 4 EGKIALVTGASRGIGRAIAETLVARGAKVIGTATSESGAQAISDYLGANGK---GLMLNV 60 EGKIA +TGA++GIG A+A TL ++GA + + + + L A + +V Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 61 TDPASIESVLENVRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFRLSKA 120 D A+I+ + + E G +DILVN AG+ R L+ + D+EW N + VF S++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 121 VMRAMMKKRHGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGITVNVVA 180 V + MM +R G I+T+GS + A YA++KA + F+K L E+A I N+V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 181 PGFIETDMTRAL-----TDEQR-AGTLA----AVPAGRLGTPNEIASAVAFLASDEASYI 230 PG ETDM +L EQ G+L +P +L P++IA AV FL S +A +I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 231 TGETLHVNGG 240 T L V+GG Sbjct: 247 TMHNLCVDGG 256
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 49.3 bits (117), Expect = 8e-08 Identities = 36/246 (14%), Positives = 67/246 (27%), Gaps = 8/246 (3%) Query: 550 PVAAAAPVAAAAPAQPGLLSRFFSALKNIFSGAEEAKPAEVQIEKKAEEKPERQQERRKP 609 P + S + A PA + E E ++ K Sbjct: 993 DTTNITTPNNIQADVPSVPSN--NEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 610 RANNRRDRNDRRDNRDNRDNRDNRDNRDTRADNAEGREPRESREENRRNRREKPSQNVEA 669 N +D + + + N + E++E +E + + Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE-KE 1109 Query: 670 RDVRQTSGDDAEKAKSRDEQQPRRERTRRRNDDKRQAQQEAKAQTREEPVVQETEQEERV 729 + + E K + P++E++ A++ +EP Q + Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Query: 730 QTLPR-----RKPRQLAQKVRVESAVVEPVAEIVPEAVVAEVIAPHSEPVKAELPAGVES 784 Q +P + V ++VVE P V + S K V S Sbjct: 1170 QPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRS 1229 Query: 785 VADQDE 790 V E Sbjct: 1230 VPHNVE 1235 Score = 45.8 bits (108), Expect = 9e-07 Identities = 46/281 (16%), Positives = 80/281 (28%), Gaps = 30/281 (10%) Query: 691 PRRERTRRRNDDKRQAQQEAKAQTREEPVVQETEQEERVQTLPRRKPRQLAQKVRVESAV 750 P E+ R + D Q V E+ RV P P S Sbjct: 983 PEVEK-RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAP-----ATPSET 1036 Query: 751 VEPVAEIVPEAVVAEVIAPHSEPVKAELPAGVESVADQDENGESREANGMPR------RS 804 E VAE + V + + + + + + N + + + Sbjct: 1037 TETVAENSKQ-ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 805 RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPEMASGKVWIRYPVVRPQDQQPEE 864 + + + ++ + + E TQ P++ S V P+ +Q E Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQE---------VPKVTSQ--------VSPKQEQSET 1138 Query: 865 VQVQDASVAKTVEAVAAPVAVVETVTAAPVTVEPATMEPVTAEPVVVEPVAAAEPLVVDA 924 VQ Q + V +T T A +PV VV+ Sbjct: 1139 VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVEN 1198 Query: 925 AEVVAPAAVEPAPQEPVTEAPAVEAPQAIAPVTLDPEPVVV 965 E PA +P + P +++ V + EP Sbjct: 1199 PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATT 1239 Score = 33.9 bits (77), Expect = 0.005 Identities = 44/271 (16%), Positives = 78/271 (28%), Gaps = 23/271 (8%) Query: 724 EQEERVQTLPRRKPRQLAQKVRVESAVVEPVAEIVPEAVVAEVIAPHSEPVKAELPAGVE 783 E E+R QT+ +V EI A V E AP P A E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI---ARVDE--APVPPPAPATPSETTE 1038 Query: 784 SVADQDENGESREANGMPRRSRRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPEM 843 +VA+ + + + ++ V+ + + + VA + E Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN------TQTNEVAQSGSET 1092 Query: 844 ASGKVWIRYPVVRPQDQQPEEVQVQDASVAKTVEAVAAPVAVVETVTAAPVTVEPATMEP 903 + + E+ + KT E + V TV+P EP Sbjct: 1093 KETQ-----TTETKETATVEKEEKAKVETEKTQEV-PKVTSQVSPKQEQSETVQPQA-EP 1145 Query: 904 VTAEPVVVEPVAAAEPLVVDAAEVVAPAAVEPAPQEPVTEAPAVEAPQAIAPVTLDPEPV 963 V A ++PVTE+ V ++ + P Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 964 VVEPEALER-----RLSLQRQLKPSPRSQKP 989 +P + +R ++ P + +P Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.0 bits (158), Expect = 4e-15 Identities = 30/166 (18%), Positives = 62/166 (37%), Gaps = 10/166 (6%) Query: 10 GKRSQAVSAKKEAILAAALEAFSQFGIHGTRLEQVAERAGVSKTNLLYYYPSKEALYVAV 69 K Q ++ IL AL FSQ G+ T L ++A+ AGV++ + +++ K L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 LQQILAIWLAPLKAFREDI--SPLVAIREYIRLKLEVSRDHPQASKLF------CLEMLQ 121 + + ++ PL +RE + LE + + +L E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTV-TEERRRLLMEIIFHKCEFVG 121 Query: 122 GAPLLMGELTGDLKALVDEKSAIVSGWIDRGKL-APVDPQHLIFMI 166 ++ D + I+ L A + + ++ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 72.4 bits (177), Expect = 4e-17 Identities = 44/184 (23%), Positives = 72/184 (39%), Gaps = 23/184 (12%) Query: 4 LPARPESLTFAPQQSALIVVDMQNAYASQGGYLDLAGFDVSATRPVIDNINTAVAAARAA 63 +P S P ++ L++ DMQN + +D S + NI Sbjct: 17 MPQNKVSWVPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQL 70 Query: 64 GMLIIWFQNGWDDQYVEAGGPGSPNYHKSNALKTMRQRPELQGKLLAKGGWDYQLVDELT 123 G+ +++ PGS N L G L G ++ +++ EL Sbjct: 71 GIPVVY-----------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELA 113 Query: 124 PQEGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGIV 183 P++ D+VL K RYS F T L ++R G L+ TGI ++ T + F + Sbjct: 114 PEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFF 173 Query: 184 LEDA 187 + DA Sbjct: 174 VGDA 177
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 201 bits (512), Expect = 7e-67 Identities = 88/133 (66%), Positives = 104/133 (78%), Gaps = 2/133 (1%) Query: 2 MKRNILAVVIPALLVAGAANAAEIYNKNGNKLDFYGKMVGEHVWTTNGDTSSDDTTYARI 61 MKR +LA+VIPALL AGAA+AAEIYNK+GNKLD YGK+ G H ++ + + D TY R+ Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDD-SSKDGDQTYMRV 59 Query: 62 GLKGETQINDQLIGYGQWEYNMDASNVEGSQT-TKTRLAFAGLKAGEYGSFDYGRNYGAI 120 G KGETQINDQL GYGQWEYN+ A+ EG + TRLAFAGLK G+YGSFDYGRNYG + Sbjct: 60 GFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVL 119 Query: 121 YDVEAATDMLVEW 133 YDVE TDML E+ Sbjct: 120 YDVEGWTDMLPEF 132
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 301 bits (772), Expect = e-104 Identities = 134/252 (53%), Positives = 162/252 (64%), Gaps = 27/252 (10%) Query: 2 GGDGWNYTDNYMTGRTNGVATYRNSDFFGLVDGLSFALQYQGKNDHDRA----------- 50 GGD + Y DNYMTGR NGVATYRN+DFFGLVDGL+FALQYQGKN+ A Sbjct: 133 GGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQSADDVNIGTNNRN 192 Query: 51 ----IRKQNGDGFSTAATYAFDNGIALSAGYSSSNRSVDQKA----DGNGDKAEAWATSA 102 IR NGDGF + TY G + A Y++S+R+ +Q GDKA+AW Sbjct: 193 NGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIAGGDKADAWTAGL 252 Query: 103 KYDANNIYAAVMYSQTYNMTP------EEDNHFAGKTQNFEAVVQYQFDFGLRPSIGYVQ 156 KYDANNIY A MYS+T NMTP D A KTQNFE QYQFDFGLRP++ ++ Sbjct: 253 KYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSFLM 312 Query: 157 TKGKDLQSRAGFSGGDADLVKYIEVGTWYYFNKNMNVYAAYKFNQLDDND-YTKAAGVAT 215 +KGKDL + +G D DLVKY +VG YYFNKN + Y YK N LDD+D + K AG++T Sbjct: 313 SKGKDL-TYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGIST 371 Query: 216 DDQAAVGIVYQF 227 DD A+G+VYQF Sbjct: 372 DDIVALGMVYQF 383
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.4 bits (112), Expect = 4e-07 Identities = 45/281 (16%), Positives = 95/281 (33%), Gaps = 20/281 (7%) Query: 347 QEKIERYEADLDELQIRLEEQNEVVAEAVDRQEENEARAEAAELEVDELKSQLADYQQAL 406 + K + L+ +E E ++ A ++ +N+ ++ EL+++ AD ++AL Sbjct: 70 KLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKAL 129 Query: 407 DVQQTRAIQYNQALQALERAKALCHLPDLTPESADEWLETFQAKEQEATEKMLSLEQKMS 466 + + + ++ LE KA L AD + + A + K+ Sbjct: 130 EGAMNFSTADSAKIKTLEAEKA-----ALAARKADL-----EKALEGAMNFSTADSAKIK 179 Query: 467 VAQTAHSQFEQAYQLVAAINGPLARNEAWDVARELLRDGVNQRHQAEQAQGLRSRLNELE 526 + + E + L + A + A A+ +LE Sbjct: 180 TLEAEKAALEARQA---ELEKALEGAMNFSTADSAKIKTLEAEKAALAAR-----KADLE 231 Query: 527 QRLREQQDAERQLAEFCKRQGKRYDIDDLETLHQELEARIASLADSVSNAQEQRMALRQE 586 + L + + K + + LE ELE + + + + L E Sbjct: 232 KALEGAMNFSTADSA--KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 289 Query: 587 LEQLQSRTQTLMRRAPVWLAAQNSLNQLCEQSGEQFASGQE 627 L++ L ++ V A + SL + + S E + Sbjct: 290 KAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330 Score = 38.1 bits (88), Expect = 3e-04 Identities = 61/363 (16%), Positives = 117/363 (32%), Gaps = 29/363 (7%) Query: 261 HLISEATNYVAADYMRHANERRIHLDKALEYRRDLFTSRSQLAAEQYKHVDMARELQEHN 320 + E + + + + +L+ + K + L E Sbjct: 53 EKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKA 112 Query: 321 GAEGDLEADY----QAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAVD 376 +LEA +A +N + + +E +A L + LE+ E Sbjct: 113 SKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST 172 Query: 377 RQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQALQA-LERAKALCHLPDL 435 EA + ++ +++L + T + L+A A + Sbjct: 173 ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 232 Query: 436 TPESADEWLETFQAKEQEATEKMLSLEQKM-SVAQTAHSQFEQAYQLVAAINGPLARNEA 494 E A + AK + + +LE + + + + A I A A Sbjct: 233 ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 292 Query: 495 WDVARELLRDGVNQRHQAEQAQGLRSRLNELEQRLREQQDAERQLAEFCK------RQGK 548 + + L +Q A + Q LR L + + ++Q +AE Q E RQ Sbjct: 293 LEAEKADLEH-QSQVLNANR-QSLRRDL-DASREAKKQLEAEHQKLEEQNKISEASRQSL 349 Query: 549 RYDID--------------DLETLHQELEARIASLADSVSNAQEQRMALRQELEQLQSRT 594 R D+D LE ++ EA SL + ++E + + + LE+ S+ Sbjct: 350 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKL 409 Query: 595 QTL 597 L Sbjct: 410 AAL 412 Score = 37.4 bits (86), Expect = 5e-04 Identities = 42/307 (13%), Positives = 102/307 (33%), Gaps = 18/307 (5%) Query: 935 QFEQLKEDYAYAQQTQRDARQQAFALAEVVQRRAHFSYSDSAEMLSGNSDLNEKLRQRLE 994 ++ +Q + Q+ E+ SD + D N++L + L Sbjct: 36 NTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELS 95 Query: 995 QAESERSRARDALRAHAAQLSQYNQVLASLKSSYDTKKELLNDLYKELQDIGVRADAGAE 1054 A+ + + +L A+++ + A L+ + + +++ + A A Sbjct: 96 NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA 155 Query: 1055 ERA--RARRDELHMQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDY-------CE 1105 +A + + + ++ LE EA L + L Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 215 Query: 1106 MREQVVTAKAGWCAVMRLVKDNGVERRLHRRELAYLSAD------ELRSMSDKALGALRL 1159 + + A + + ++ ++ L A+ + GA+ Sbjct: 216 LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF 275 Query: 1160 AVADNEHLRDVLRISEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIEL 1219 + AD+ ++ + + + ++ V R+ +R+D+ D EA +Q+E E Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL---DASREAKKQLEAEH 332 Query: 1220 SRLTEEL 1226 +L E+ Sbjct: 333 QKLEEQN 339 Score = 36.2 bits (83), Expect = 0.001 Identities = 51/327 (15%), Positives = 96/327 (29%), Gaps = 15/327 (4%) Query: 782 ARENRIETLHAERESLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFEDDPEEEIRKL 841 A ++ + L E + E+ + + Q + E Sbjct: 82 ALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADL------EKALEGAMNF 135 Query: 842 NSRRGELERALSAHESDNQQNRVQYEQAKEGVSALNRLLPRLNLLADDTLADRVDEIQER 901 ++ + L A ++ + E+A EG + + A E Sbjct: 136 STADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAEL 195 Query: 902 LDEAQEAARFIQQHGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYAQQTQRDARQQAFALA 961 + A F ++ LE + L + E+ E + A Sbjct: 196 EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEK 255 Query: 962 EVVQRRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAESERSRARDALRAHAAQLSQYNQVL 1021 ++ R ++ + L G + + +++ E+E++ Q N Sbjct: 256 AALEAR----QAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 1022 ASLKSSYDTKKELLNDLYKELQDIGVRADAGAEERARARRDELHMQLSNNRSRRNQLEKA 1081 SL+ D +E L E Q + + R RRD L +R + QLE Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD-----LDASREAKKQLEAE 366 Query: 1082 LTFCEAEMDNLTRKLRKLERDYCEMRE 1108 E + + L RD RE Sbjct: 367 HQKLEEQNKISEASRQSLRRDLDASRE 393
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.030 Identities = 14/74 (18%), Positives = 29/74 (39%), Gaps = 1/74 (1%) Query: 128 ITYDSEQVASSSSSALITVVREGASIIGLFVMMFYYSWQLSLILIVLAPIVSVAIRVVSK 187 YD+ S ++ + E ++ L + +F + + +LI + P+V + + Sbjct: 325 YPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILA 384 Query: 188 RFRNISKNMQNTMG 201 F S N G Sbjct: 385 AF-GYSINTLTMFG 397
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 116 bits (293), Expect = 5e-38 Identities = 33/88 (37%), Positives = 57/88 (64%), Gaps = 1/88 (1%) Query: 2 TKSELIERLASQQSHIPAKAVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTG 61 K +LI ++A + + + K AV + ++S LA+GE++++ GFG+F + RA R G Sbjct: 3 NKQDLIAKVA-EATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGDKVELEGKYVPHFKPGKELRDR 89 RNP+TG++++++ VP FK GK L+D Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDA 89
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 22/106 (20%), Positives = 35/106 (33%), Gaps = 6/106 (5%) Query: 301 LMIGMITFQFSSFSFGIGNAAGLLFAGIML-GFLRANHPTFG-YIPQ--GALNMVKEFGL 356 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 357 MVFMAGVGLSAGAGINNGLGAVGGQM--LAAGLIVSLVPVVICFLF 400 M G G+ AG + +G AA + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 32.5 bits (74), Expect = 0.005 Identities = 32/121 (26%), Positives = 44/121 (36%), Gaps = 29/121 (23%) Query: 446 WLGNLASALDGFVKRHPQLTAALFKIAAVFAVVATAAGVVSLA------------LASIL 493 W G L + L GFV L A+ A + V+ + L L + L Sbjct: 167 WGGLLFNLLGGFVS----LGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAAL 222 Query: 494 GPMAVLRVSAGILQLIFASAFGLVTRVIGGAGQAVIWLGRLMMANPI-----LAIVGLIA 548 G A L A + L+ +S G G +I L + PI LAI G IA Sbjct: 223 G--AWLGWQALPIVLLLSSLVGAF------MGIGLILLRNHHQSKPIPFGPYLAIAGWIA 274 Query: 549 M 549 + Sbjct: 275 L 275
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 4e-10 Identities = 17/76 (22%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 1 MAR--RPNDPQRRERILQATLDTIAAHGIHAVTHRKIATCANVPLGSLTYYFSGIEALIE 58 MAR + + R+ IL L + G+ + + +IA A V G++ ++F L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 59 EAFSLFTAEMSAQYQQ 74 E + L + + + Sbjct: 61 EIWELSESNIGELELE 76
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.026 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGGIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (296), Expect = 2e-34 Identities = 74/255 (29%), Positives = 119/255 (46%), Gaps = 16/255 (6%) Query: 3 LKDKVAIITGAASARGLGFATAKLFAENGAKVVIIDLNGEAS---KTAAAALGEGHLGLA 59 ++ K+A ITGAA +G+G A A+ A GA + +D N E ++ A Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 60 ANVADEVQVQAAIEQILAKYGRVDVLVNNAGITQPLKLMDIKRANYDAVLDVSLRGTLLM 119 A+V D + +I + G +D+LVN AG+ +P + + ++A V+ G Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 120 SQAVIPTMRAQKSGSIVCISSVSAQRGGGIFGGPHYSAAKAGVLGLARAMARELGPDNVR 179 S++V M ++SGSIV + S A G Y+++KA + + + EL N+R Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 180 VNCITPGLIQTDITAGKLTDD---------MTANILAGIPMNRLGDAIDIARAALFLGSD 230 N ++PG +TD+ D+ GIP+ +L DIA A LFL S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 231 LSSYSTGITLDVNGG 245 + + T L V+GG Sbjct: 242 QAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.7 bits (103), Expect = 1e-06 Identities = 57/400 (14%), Positives = 128/400 (32%), Gaps = 50/400 (12%) Query: 22 LTMIFLVYAINYADRTNIGAVLPFIIDEFHINNFEAGAIASMFFLGYAVSQIP----AGF 77 L +I A++ I VLP ++ + +N + L YA+ Q G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGA 65 Query: 78 FIAKRGTRGLVSLSIFGFSAFTWLMGTVSSVFGLKLVRLGLGLSEGPCPVGLASTINNWF 137 + G R ++ +S+ G + +M T ++ L + R+ G++ V + I + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAV-AGAYIADIT 124 Query: 138 PPKEKATATGVYIAATMFAPIIVPPLAVWIAVTWGWRWVFFSFAIPGIVAAIAWYLLVKS 197 E+A G +++A ++ P+ + + FF+ A + + L+ Sbjct: 125 DGDERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL-- 181 Query: 198 KPAESGFVSQSELAEINAGRESHNNSVR-ENILIAERFTWLDKIIRVKKMAPIDTAKGLF 256 ESH R + +A + + Sbjct: 182 -------------------PESHKGERRPLRREALNPLASFRWARGMTVVAAL-----MA 217 Query: 257 TSKNILGDCLAYFMMVSVLYGLLTWIPLYLVKERGFDVMSMGFVASMPCIGGFIGAIGGG 316 +F+M V ++ +D ++G + G + ++ Sbjct: 218 V----------FFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLA---AFGILHSLAQA 264 Query: 317 WVSDKLLGR-RRKPTMMFTAVSTVVMMLIMLNIPASTLAVCIGLFFVGFCLNIGWPAFTA 375 ++ + R + +M ++ +++ +A I + IG PA A Sbjct: 265 MITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG--GIGMPALQA 322 Query: 376 YGMAVSDSKTYPIASSIINSGGNLGGFVAPMAAGFLLDKT 415 D + + + +L V P+ + + Sbjct: 323 MLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.4 bits (87), Expect = 1e-04 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 16/86 (18%) Query: 71 VRDGRIAAIVA------EDDV-----PSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEW 119 ++DGRIAAI + V P I EG++VT G +D H H + Q Sbjct: 90 LKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI---CPQQIE 146 Query: 120 EQRLNGVSYQTISASGGGINSTVRAT 145 E ++G++ + G G AT Sbjct: 147 EALMSGLT--CMLGGGTGPAHGTLAT 170
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 28.0 bits (62), Expect = 0.048 Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 8/85 (9%) Query: 67 QTDIDSLRGQIQENQYQLNQIVER------QKQILLQIDSLSSGG--GAASGAQAPSSSG 118 +D + E Y N + Q I Q+ + GG GA S AP + Sbjct: 266 TAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGALSNQPAPPNEA 325 Query: 119 DQSAAATSAAPAATSGAPAMTGDAN 143 + T+ A + + + ++N Sbjct: 326 PIATPPTNQQNAQNTPQTSTSTNSN 350
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (291), Expect = 7e-34 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 4/119 (3%) Query: 56 EEQARLQMQQLQQNNIVYFDLDKYDIRSDFAAMLDAHANFLRSN--PSYKVTVEGHADER 113 +Q + + V F+ +K ++ + A LD + L + V V G+ D Sbjct: 205 APAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264 Query: 114 GTPEYNIALGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYAKNRRAVL 172 G+ YN L ERRA +V YL KG+ AD+IS G+ P V G+ K R A++ Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALI 321
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 65.1 bits (158), Expect = 3e-13 Identities = 29/233 (12%), Positives = 75/233 (32%), Gaps = 8/233 (3%) Query: 68 QQQASARRAAEQREKQAQQQAEELREKQAAEQERLKQLEQERLQAQEAAKEAKEQ----Q 123 + A + + AE +++ ++ + + Q +E AKEAK Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 124 KQAEEAAAKAAAAAKAKADAQAKEAQEAAAKAAAEAKAKADAQAKAAEQAAAKAAADA-K 182 + E A + + + + E KA E + + ++ + + ++ + Sbjct: 1081 QTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQ 1140 Query: 183 KQAEAAAAKAAAEAKKQAEAEAAKAAAEAQKKAEAAAAKKAQQEAEKKAQQEAAKQAAAE 242 QAE A K+ +++ A Q E ++ + + ++ + E Sbjct: 1141 PQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE---QPVTESTTVNTGNSVVE 1197 Query: 243 KAAAEKAAEKAAAQKAAAEKAAAEKAAAAEKAAAAKAAAAEKAAADKAAKAAA 295 A + + + + ++ A ++ D++ A Sbjct: 1198 NPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALC 1250 Score = 57.0 bits (137), Expect = 1e-10 Identities = 35/276 (12%), Positives = 72/276 (26%), Gaps = 7/276 (2%) Query: 66 QQQQQASARRAAEQREKQAQQQAEELREKQAAEQERLKQLEQERLQAQEAAKEAKEQQKQ 125 +Q++ EQ + Q E A E + + + + ++ E KE Q Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNRE----VAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 126 AEEAAAKAAAAAKAKADAQAKEAQEAAAKAAAEAKAKADAQAKAAEQAAAKAAADAKKQA 185 + A KAK + E + K ++ K + QA D Sbjct: 1099 ETKETATVEKEEKAKVET---EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 186 EAAAAKAAAEAKKQAEAEAAKAAAEAQKKAEAAAAKKAQQEAEKKAQQEAAKQAAAEKAA 245 + ++ A + A+ + E + A Q + Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSES 1215 Query: 246 AEKAAEKAAAQKAAAEKAAAEKAAAAEKAAAAKAAAAEKAAADKAAKAAAAKAAAAKKAA 305 + K + + ++ + + A AKA Sbjct: 1216 SNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNV 1275 Query: 306 AAKEADGVDNLLGDLSSGKNAPKTGGGAKGNNASAA 341 + + L + N + N +S+ Sbjct: 1276 GKAVSQHISQLEMNNEGQYNVWVSNTSMNKNYSSSQ 1311 Score = 56.2 bits (135), Expect = 2e-10 Identities = 38/273 (13%), Positives = 81/273 (29%), Gaps = 7/273 (2%) Query: 85 QQQAEELREKQAAEQERLKQLEQERLQAQEAAKEAKEQQKQAEEAAAKAAAAAKAKADAQ 144 ++ + + Q + + + ++ A A + + A+ Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE-N 1043 Query: 145 AKEAQEAAAKAAAEAKAKADAQAKAAEQAAAKAAADAKKQAEAAAAKAAAEAKKQAEAEA 204 +K+ + K +A + A++A + A+ + A + E + E Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 205 AKAAAEAQKKAEAAAAKKAQQEAEKKAQQEAAKQAAAE--KAAAEKAAEKAAAQKAAAEK 262 A E + K E QE K Q + KQ +E + AE A E + Sbjct: 1104 ATVEKEEKAKVETEK----TQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 263 AAAEKAAAAEKAAAAKAAAAEKAAADKAAKAAAAKAAAAKKAAAAKEADGVDNLLGDLSS 322 + A E+ A ++ E+ + + N Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP 1219 Query: 323 GKNAPKTGGGAKGNNASAAGSGNTKNSASGADI 355 ++ N A S N +++ + D+ Sbjct: 1220 KNRHRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252 Score = 54.3 bits (130), Expect = 6e-10 Identities = 29/235 (12%), Positives = 71/235 (30%), Gaps = 4/235 (1%) Query: 64 NRQQQQQASARRAAEQREKQAQQQAEELREKQAAEQERLKQLEQERLQAQEAAKEAKEQQ 123 NR+ ++A + A + + Q E +E Q E + +E+E E K + + Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPK 1124 Query: 124 KQAEEAAAKAAAAAKAKADAQAKEAQEAAAKAAAEAKAKADAQAKAAEQAAAKAAADAKK 183 ++ + + + QA+ A+E + EQ A + +++ ++ Sbjct: 1125 VTSQVSPKQEQSETVQP---QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQ 1181 Query: 184 QAEAAAAKAAAEAKKQAEAEAAKAAAEAQKKAEAAAAKKAQQEAEKKAQQEAAKQAAAEK 243 + + + A + +E++ K + ++ + A Sbjct: 1182 PVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSS 1241 Query: 244 AAAEKAAEKAAAQKAAAEKAAAEKAAAAEKAAAAKAAAAEKAAADKAAKAAAAKA 298 A ++ A A+ A A + + Sbjct: 1242 NDRSTVAL-CDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPHMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.3 bits (65), Expect = 0.036 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 4/115 (3%) Query: 361 ILTLSARWSAAY-GQSSMPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYM 419 +LT+ + +A + G +S+ L +GLAVM E+ +S I + P + VL + Sbjct: 324 LLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLME 383 Query: 420 LLSGAIANYLAGVIAD-QTSQASFDAAGAVNYSID--AYITVFSQITWGALACVG 471 L+ AI L G+ D +T++ + GA+ +I A I V + + GA A +G Sbjct: 384 LIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLG 438
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.047 Identities = 24/130 (18%), Positives = 48/130 (36%), Gaps = 28/130 (21%) Query: 760 HIQLDLPDPLQLVHVDGPLFERVLINLLENAHKYAGAR----ASIGIRAEADARQLSLEV 815 + + + V V P ++ L+EN K+ A+ I ++ D ++LEV Sbjct: 241 QFENQINPAIMDVQV--PPM--LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 816 WDNGPGIPAGQEQTIFDKFARGNKESAIPGVGLGLA-ICQAIVDVHGG--TISASNRPEG 872 + G ++ G GL + + + ++G I S + +G Sbjct: 297 ENTGS----------------LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEK-QG 339 Query: 873 GASFRVTLPG 882 + V +PG Sbjct: 340 KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 1/122 (0%) Query: 4 VLIIEDEHAIRRFLRTALEADGMRVFEAETLQRGLIEAATRKPDLAILDLGLPDGDGIDF 63 +L+ +D+ AIR L AL G V A DL + D+ +PD + D Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 IRDLRQ-WSQMPIIVLSARSEEHDKIAALDAGADDYLSKPFGIGELQARLRVALRRHGAA 122 + +++ +P++V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 123 QA 124 + Sbjct: 126 PS 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.7 bits (85), Expect = 1e-04 Identities = 15/32 (46%), Positives = 22/32 (68%) Query: 345 LETLLQENGNVVRAADRLGLHRNTLHQRIQRI 376 L L GN ++AAD LGL+RNTL ++I+ + Sbjct: 442 LAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 53/313 (16%), Positives = 106/313 (33%), Gaps = 26/313 (8%) Query: 99 LGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIW 158 + L +A +M +L I + G + G A +A ER +G Sbjct: 78 VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAY-IADITDGDERARHFGFM 136 Query: 159 STAHNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINV 218 S G V V+ ++ GF + + AAL + + +S + P Sbjct: 137 SACFGFG-MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP---- 191 Query: 219 IRDEPQEEVEARGSVFKNQLLALRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYS 278 EA + + +A+ + + W I F E + Sbjct: 192 ------LRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI-FGEDRFHWD 244 Query: 279 TLEASGIIGVN-AIAGIAGTIIAGMLSDRF---FPRNRSVMAGFISLLNTAGFALMLWSP 334 IG++ A GI ++ M++ R++M G I+ + G+ L+ ++ Sbjct: 245 A----TTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIA--DGTGYILLAFAT 298 Query: 335 HNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLT 394 + M++ A+ G L +++ + + G G++ + + +G L Sbjct: 299 R-GWMAFPIMVLL-ASGGIGMPALQAMLSRQVDEER-QGQLQGSLAALTSLTSIVGPLLF 355 Query: 395 GIIIDKTAILENG 407 I + NG Sbjct: 356 TAIYAASITTWNG 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (341), Expect = 5e-41 Identities = 87/253 (34%), Positives = 130/253 (51%), Gaps = 15/253 (5%) Query: 5 LTGKKALVTGASRGLGRAIALSLARAGADVVITYEKSVDKAQAVADEIKALGRYGEAVQA 64 + GK A +TGA++G+G A+A +LA GA + + + +K + V +KA R+ EA A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 65 DSASAQAIQDAVTHAARSLGGLDILVNNAGIARGGPLESMTLADIDALINVNIRGVVIAT 124 D + AI + R +G +DILVN AG+ R G + S++ + +A +VN GV A+ Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 125 QEALVHMAD--GGRIINIGSCLANRVAMPGIAVYAMTKSALNALTRGLARDLGPRGITVN 182 + +M D G I+ +GS A +A YA +K+A T+ L +L I N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRT-SMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 183 LVHPGPTNSDMN-----PEDGEQ------AEAQRQMIAVGHYGQPEDIAAAVTFLASPAA 231 +V PG T +DM E+G + E + I + +P DIA AV FL S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 232 GQISGTGLDVDGG 244 G I+ L VDGG Sbjct: 244 GHITMHNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.014 Identities = 9/60 (15%), Positives = 25/60 (41%), Gaps = 1/60 (1%) Query: 172 VIILAVLAMIVVKALTHSPWG-TYTVAFTIPLAIFMGIYIRYLRPGRIGEVSVIGLVMLV 230 ++ ++ + + + A + W +V +PL I + L + ++GL+ + Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 340 bits (873), Expect = e-121 Identities = 109/265 (41%), Positives = 151/265 (56%), Gaps = 20/265 (7%) Query: 1 MAALDFRGQTVWVTGAGKGIGYATALAFVEAGANVTGFD---------------LAFDGE 45 M A G+ ++TGA +GIG A A GA++ D A E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 46 SYPFATETLDVADADQVREACSRLLANTERLDVLVNAAGILRMGATDQLSAEDWQQTFAV 105 ++P DV D+ + E +R+ +D+LVN AG+LR G LS E+W+ TF+V Sbjct: 61 AFP-----ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSV 115 Query: 106 NVGGAFNLFQQTMAQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLEL 165 N G FN + +R G+IVTV S+ A PR M+AY +SKAA +GLEL Sbjct: 116 NSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 166 AGSGVRCNLVSPGSTDTDMQRTLWVSDDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTI 225 A +RCN+VSPGST+TDMQ +LW ++ +Q I+G E FK GIPL K+A+P +IA+ + Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235 Query: 226 LFLASSHASHITLQDIVVDGGSTLG 250 LFL S A HIT+ ++ VDGG+TLG Sbjct: 236 LFLVSGQAGHITMHNLCVDGGATLG 260
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 426 bits (1096), Expect = e-154 Identities = 152/303 (50%), Positives = 201/303 (66%), Gaps = 20/303 (6%) Query: 1 MAIPKLQAYALPEASDIPANKVNWAFEPSRAALLIHDMQEYFLNFWGENSAMMEKVVANI 60 MAIP +Q Y +P ASD+P NKV+W +P+RA LLIHDMQ YF++ + ++ + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDFCKQNGIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQQVIAALAPDEDDTV 120 L++ C Q GIPV YTAQP Q+ +DRALL D WGPGL P ++++I LAP++DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEEMLKETGRDQLIITGVYAHIGCMTTATDAFMRDIKPFFVADALAD 180 L KWRYSAF R+ L EM+++ GRDQLIITG+YAHIGC+ TA +AFM DIK FFV DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSREEHLMALKYVAGRSGRVVMTEELL--------PIPVSKA-----------ALRALIL 221 FS E+H MAL+Y AGR VMT+ LL + + A +R I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 222 PLLDESDEPLD-DENLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWALLTR 280 LL E+ E + E+L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W LLT Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLTT 300 Query: 281 EVQ 283 Q Sbjct: 301 RSQ 303
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 51.5 bits (123), Expect = 1e-09 Identities = 59/288 (20%), Positives = 99/288 (34%), Gaps = 31/288 (10%) Query: 40 HTLPSQPLRIVSTSVTLTGSLLAIDAPVVASGATTPNNRVADSQGFLRQWSEVAKARKLA 99 H P RIV+ LLA+ VAD+ + SE + Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINYRLWVSEPPLPDSV- 78 Query: 100 RLYIG---EPSAEAVAAQMPDLILVSATGGDSALPLYDQLKTIAPTLVINYDDKS----- 151 + +G EP+ E + P ++ SA G P + L IAP N+ D Sbjct: 79 -IDVGLRTEPNLELLTEMKPSFMVWSAGYG----PSPEMLARIAPGRGFNFSDGKQPLAM 133 Query: 152 WQTLLTQLGQITGHEQQASARIADFNKQLVSLKEKMKLPPQPVTALVYTAAAHSANIWTP 211 + LT++ + + A +A + + S+K + L ++ P Sbjct: 134 ARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGP 193 Query: 212 ESAQGQMLQQLGFSLATLPGGLPASHSQGKRHDIVQLGGENLAAGLNGQSLFLFAGDQKD 271 S ++L + G A + + + LAA + L + KD Sbjct: 194 NSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKD 245 Query: 272 ADAIYANPLLAHLPAVAGKRVYPLGTETFRLDYYSALLVLQRLSSLFG 319 DA+ A PL +P V R + F SA+ ++ L + G Sbjct: 246 MDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIG 293
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.2 bits (81), Expect = 4e-04 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 8/187 (4%) Query: 24 IARFISILSLGLLGVAIPVQIQMMTHSTWQVGLSVTLTGASMFVGLMVGGVLADRYKRKR 83 I F S+L+ +L V++P T + +G V G L+D+ KR Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 84 LILLARGTCGVGFVGLCLNALLPEPSLAAIYLLGIWDGFFASLGVTALLAATPALVGREN 143 L+L G V + + A ++ G F +L ++ + +EN Sbjct: 81 LLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL----VMVVVARYIPKEN 136 Query: 144 LMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNFGLAAAGTFITTLTLLRLPQLPPPP 203 +A + V +G + P IGG++ + W++ L IT +T+ L +L Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIP--MITIITVPFLMKLLKKE 192 Query: 204 QPREHPL 210 + Sbjct: 193 VRIKGHF 199
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 2e-39 Identities = 75/262 (28%), Positives = 118/262 (45%), Gaps = 12/262 (4%) Query: 3 RDFQNKTVVITGACRGIGAGIAERFARDGANLVMV---SNAERVHETAETLRQRYQADIL 59 + + K ITGA +GIG +A A GA++ V ++ R+ Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE--- 60 Query: 60 SLQVDVTDEAQVQGLYEQAAARFGTIDVSIQNAGVITIDYYDRMPKADFEKVLAVNTTGV 119 + DV D A + + + G ID+ + AGV+ + ++E +VN+TGV Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 120 WLCCREAAKYMVKQNHGSLINTSSGQGRQGFIYTPHYAASKMGVIGITQSLAHELAPWNI 179 + R +KYM+ + GS++ S YA+SK + T+ L ELA +NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 180 TVNAFCPGIIESEMWDYNDRVWGEILSTEQKRYGKGELMAEWVEGIPMKRAGKPEDVAGL 239 N PG E++M +W + EQ G E + GIP+K+ KP D+A Sbjct: 181 RCNIVSPGSTETDM---QWSLWADENGAEQVIKGSLE---TFKTGIPLKKLAKPSDIADA 234 Query: 240 VAFLASDDARYLTGQTINIDGG 261 V FL S A ++T + +DGG Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 130 bits (327), Expect = 9e-39 Identities = 78/251 (31%), Positives = 129/251 (51%), Gaps = 12/251 (4%) Query: 16 RVAFVTGAGSGIGQTIACSLASAGARVVCFDLRDDGGLAETVSHIESIGGQACSYNGDVR 75 ++AF+TGA GIG+ +A +LAS GA + D + L + VS +++ A ++ DVR Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEK-LEKVVSSLKAEARHAEAFPADVR 67 Query: 76 QIADLRAAVALAKSRYGRLDIAVNAAGIANANPALEMESEQWQRVIDINLTGVWNSCKAE 135 A + A + G +DI VN AG+ + E+W+ +N TGV+N+ ++ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 136 AELMLESGGGSIINIASMSGIIVNRGLDQAHYNCSKAGVIHLSKSLAMEWVGKGIRVNSI 195 ++ M++ GSI+ + S + + A Y SKA + +K L +E IR N + Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSM--AAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 196 SPGYTATPM--------NTRPEMVHQTRE-FESQTPMQRMAKVEEMAGPALFLASDAASF 246 SPG T T M N +++ + E F++ P++++AK ++A LFL S A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 247 CTGVDLVVDGG 257 T +L VDGG Sbjct: 246 ITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 5e-15 Identities = 31/172 (18%), Positives = 58/172 (33%), Gaps = 15/172 (8%) Query: 10 RRRQLIDATLDAINEVGMHDATIAQIARRAGVSTGIISHYFKDKNGLLEATMRDITSQLR 69 R+ ++D L ++ G+ ++ +IA+ AGV+ G I +FKDK+ L S + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 DAVLNRLHALPDGSASQRLQAIVGGNFDETQISSAAMKAWLAFWASSMHQP-------ML 122 + L P L+ I+ + T ++ + + Sbjct: 72 ELELEYQAKFPGDPL-SVLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 123 YRLQQVSSRRLLSNLVYEFRRE---LPREQAQEAGYGLAALIDGL---WLRA 168 R + S + + + A + I GL WL A Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 83.9 bits (207), Expect = 2e-21 Identities = 52/187 (27%), Positives = 84/187 (44%), Gaps = 5/187 (2%) Query: 6 VVFITGATSGFGEAAAQVFADAGWSLVLSGRRYPRLKALQ--DRLAARVPVHIIELDVRD 63 + FITGA G GEA A+ A G + +L+ + + AR DVRD Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFPADVRD 68 Query: 64 SEAVAAAVASLPADFADITTLINNAGLALSPLPAQEVALEDWKTMIDTNVTGLVTVTHAL 123 S A+ A + + I L+N AG+ L P ++ E+W+ N TG+ + ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 124 LPTLIRHGAGASIINIGSIAGQWPYPGSHVYGASKAFVKQFSYNLRCDLLGTGVRVTDLA 183 ++ +G SI+ +GS P Y +SKA F+ L +L +R ++ Sbjct: 128 SKYMMDRRSG-SIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 184 PGIAETE 190 PG ET+ Sbjct: 187 PGSTETD 193
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 914 bits (2363), Expect = 0.0 Identities = 416/1034 (40%), Positives = 607/1034 (58%), Gaps = 17/1034 (1%) Query: 1 MLTFFIRRPRFAMVIALLLTFVGAVSLKLIPVEQYPAITPPVVNVSASWPGASASDVAEA 60 M FFIRRP FA V+A++L GA+++ +PV QYP I PP V+VSA++PGA A V + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 IAAPLETQLNGVDHMLYMESTSSDEGTYRLSITFAAGTDADLAAIDVQNRVAQALAQLPA 120 + +E +NG+D+++YM STS G+ +++TF +GTD D+A + VQN++ A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQNGVQVRKRASNLLMGVSLYSPLGTLTPLFVSNYASTQVREALARLPGVGEVQMFGA 180 EVQQ G+ V K +S+ LM S T +S+Y ++ V++ L+RL GVG+VQ+FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 RDYSMRIWLRPDRMNALNITTDDVAQALREQNVQGAAGQVGTPPVFNGQQQTLTINGLGR 240 + Y+MRIWL D +N +T DV L+ QN Q AAGQ+G P GQQ +I R Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LNEAASFGEIIIRRGAQGQLVRLADVATIELGARSYSSGAQLNGKASAYLGIYPTPTANA 300 FG++ +R + G +VRL DVA +ELG +Y+ A++NGK +A LGI ANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LQVASAVRAELNRLHTRFPADLTWEVKFDTTRFVAATIKEIGVSLALTLLAVVVVVSLFL 360 L A A++A+L L FP + +DTT FV +I E+ +L ++ V +V+ LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QSWRATLIVVLAIPVSLIGTFAVLYLLGYSANTLSLFAIILALTMVVDDAIVVVENVETK 420 Q+ RATLI +A+PV L+GTFA+L GYS NTL++F ++LA+ ++VDDAIVVVENVE Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 MAE-GLDRLQATAQALRQIAGPVIATTLVLLAVFVPVALLPGIVGELYRQFAVTLSTAVA 479 M E L +AT +++ QI G ++ +VL AVF+P+A G G +YRQF++T+ +A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 480 LSSLVALTLTPALCALLLRPRPARP----AAVWRAFNRLLDGTRDGYGRLVGRMNRRPWL 535 LS LVAL LTPALCA LL+P A + FN D + + Y VG++ Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 536 ALAATVAAGALVAFSFTSMPKGFLPQEDQGYLFASVQLPEAASLERTEAVMAQARKLLMA 595 L A + F +P FLP+EDQG +QLP A+ ERT+ V+ Q + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 596 NPA--VEDVIQVSGFNILNGTSASNGGFISVMLKDWHQRPP----LDAVMADIQRQLLSL 649 N VE V V+GF+ A N G V LK W +R +AV+ + +L + Sbjct: 600 NEKANVESVFTVNGFSF--SGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 650 PEATIMTFAPPTLPGLGNASGFDLRILAQAGQSSAELEQVTREILQLANQH-SQLSRVFT 708 + ++ F P + LG A+GFD ++ QAG L Q ++L +A QH + L V Sbjct: 658 RDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 709 TWSSNVPQLTLTVDRDRAALLDVPVAQIFSSLQTAFGGTRAGDFSRNNRVYHVVMQNEMQ 768 + Q L VD+++A L V ++ I ++ TA GGT DF RV + +Q + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 769 WRERAEQISELYVRSRDGERVRLSNLVTITPTVGAPFIQQYNQFPSVSVSGSAAEGVSSR 828 +R E + +LYVRS +GE V S T G+P +++YN PS+ + G AA G SS Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 829 TAMAAMEQILQAHLPPGYDYAWSGISWQEQQTGNQAVWIVLAAVAMAWLFLVAQYESWTL 888 AMA ME + LP G Y W+G+S+QE+ +GNQA +V + + +L L A YESW++ Sbjct: 838 DAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 889 PASVMLSVLFAIGGALLWLWTAGYANDVYVQIGLVLLIALAAKNAILIVEFARSRRE-EG 947 P SVML V I G LL NDVY +GL+ I L+AKNAILIVEFA+ E EG Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 948 LSIVDAAREGATRRFRAVMMTAVSFIIGIMPMMLATGAGAQSRRIIGTTVFSGMLVATMV 1007 +V+A R R ++MT+++FI+G++P+ ++ GAG+ ++ +G V GM+ AT++ Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 1008 GILFIPSLYVLFQR 1021 I F+P +V+ +R Sbjct: 1017 AIFFVPVFFVVIRR 1030 Score = 75.6 bits (186), Expect = 7e-16 Identities = 88/521 (16%), Positives = 180/521 (34%), Gaps = 43/521 (8%) Query: 531 RRPWLALAATVAAGALVAFSFTSMPKGFLPQEDQGYLFASVQLPEAASLERTEAVMAQAR 590 RRP A + A + +P P + S P A + + V Sbjct: 7 RRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV----- 61 Query: 591 KLLMANPAVEDVIQVSGFNILNGTSASNGGFISVMLKDWHQRPPLDA---VMADIQRQLL 647 +++ + ++ TS S G +++ L P A V +Q Sbjct: 62 ----TQVIEQNMNGIDNLMYMSSTSDSAGS-VTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 648 SLPEATIMTFAPPTLPGLGNASGFDLRILAQAGQSSAELEQVTREILQLANQHSQLSRV- 706 LP+ + ++S + + + + Q +N LSR+ Sbjct: 117 LLPQE----VQQQGISVEKSSSSYLMVAGFVS--DNPGTTQDDISDYVASNVKDTLSRLN 170 Query: 707 ----FTTWSSNVPQLTLTVDRDRAALLDVPVAQIFSSLQTAFGGTRAGDF------SRNN 756 + + + + +D D + + + L+ AG Sbjct: 171 GVGDVQLFGAQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQ 229 Query: 757 RVYHVVMQNEMQWRERAEQISELYVR-SRDGERVRLSNLVTITPTVGA-PFIQQYNQFPS 814 ++ Q + E+ ++ +R + DG VRL ++ + I + N P+ Sbjct: 230 LNASIIAQTRFK---NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPA 286 Query: 815 VSVSGSAAEGVSSR-TAMAAMEQI--LQAHLPPG--YDYAWSGISWQEQQTGNQAVWIVL 869 + A G ++ TA A ++ LQ P G Y + + + ++ V + Sbjct: 287 AGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI-HEVVKTLF 345 Query: 870 AAVAMAWLFLVAQYESWTLPASVMLSVLFAIGGALLWLWTAGYANDVYVQIGLVLLIALA 929 A+ + +L + ++ ++V + G L GY+ + G+VL I L Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLL 405 Query: 930 AKNAILIVE-FARSRREEGLSIVDAAREGATRRFRAVMMTAVSFIIGIMPMMLATGAGAQ 988 +AI++VE R E+ L +A + ++ A++ A+ +PM G+ Sbjct: 406 VDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 989 SRRIIGTTVFSGMLVATMVGILFIPSLYVLFQRMREWAHRR 1029 R T+ S M ++ +V ++ P+L + H Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHE 506
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 1e-14 Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 10/136 (7%) Query: 2 LFIDEVHRLPPEGQEKLFHFMDNGSWRRLGESADERSATVRLIFASTEDLEK-----HFL 56 LF+DE+ +P + Q +L + G + +G + VR++ A+ +DL++ F Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVG-GRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 57 ATFIRRIPVI-VKILPIAERGQFERLAFIHHFFRREAQRLNHD-LALDGEIVSQLMRETL 114 R+ V+ +++ P+ +R E + + F ++A++ D D E + + Sbjct: 294 EDLYYRLNVVPLRLPPLRDRA--EDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPW 351 Query: 115 EGNVGGLENLIRNICA 130 GNV LENL+R + A Sbjct: 352 PGNVRELENLVRRLTA 367
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.3 bits (58), Expect = 0.047 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 89 QALCADRQDSLAQLIGAQGSLQEALRQCKAAISYPGAGLPLLLRGPTGTGK 139 L D QD + L+G ++QE R + L L++ G +GTGK Sbjct: 127 SKLEDDSQDGMP-LVGRSAAMQEIYRVLARLMQTD---LTLMITGESGTGK 173
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.8 bits (67), Expect = 0.012 Identities = 18/87 (20%), Positives = 32/87 (36%), Gaps = 10/87 (11%) Query: 199 AMAEHRGDPAWENKLARFFAASSEFEALWHQRYEVRGVENQIKHFNHPQLGRFSLQQMYW 258 A+ + ++E + + + + + YEV I H N PQ+G L Sbjct: 13 ALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEV-----VITHGNGPQVGSLLLHMDAG 67 Query: 259 YSAPRNGSRLLVYLPMDEAGEQALAWL 285 + + PMD AG + W+ Sbjct: 68 QATYGIPA-----QPMDVAGAMSQGWI 89
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 104 bits (260), Expect = 4e-26 Identities = 77/409 (18%), Positives = 161/409 (39%), Gaps = 29/409 (7%) Query: 21 MLPLIDTSITNVALDAITHTLAASATQLELIVALYGVAFAVCLAMGSKLGDNYGRRRLFM 80 +++ + NV+L I + + + + F++ A+ KL D G +RL + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 81 WGVALFGIASLLCGMANSIGALL-AARTLQGAGAALIVPQILATLHVTLKGPAH-ARAIS 138 +G+ + S++ + +S +LL AR +QGAGAA P ++ + + +A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIPKENRGKAFG 142 Query: 139 LYGGIGGIAFIVGQMGGGWLVSADIAGLGWRNAFFINVPICLLVLALSRRYVPETRRETP 198 L G I + VG GG + + W ++ + +P+ ++ + + Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHY----IHW--SYLLLIPMITIITVPFLMKLLKKEVRIK 196 Query: 199 SRIDWQGTLYL-ALILCCLLFPMALGPELHWPLWLQLMLVAVLPLLFAMRQSALRQQQRG 257 D +G + + I+ +LF + L++ + L+F ++ ++ Sbjct: 197 GHFDIKGIILMSVGIVFFMLFTTSY-------SISFLIVSVLSFLIF------VKHIRKV 243 Query: 258 DHPLLPPRLLQLTSIRFGMAIALLFFGAWSGFMFCMALTMQEGLGMAPWQSGNSFIALG- 316 P + P L + G+ + FG +GF+ + M++ ++ + G+ I G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 317 VAYFISALYAPRLIARYSMGRILLTGLAVQIAGLLLLCATFSRFGVATNALTLVPATALI 376 ++ I L+ R +L G+ L F + T + + + Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-----FLLETTSWFMTIIIVFV 358 Query: 377 GYGQALIVNSFYRIGMRDISASDAGAGSAILSTLQQATLGLGPAILGSL 425 G + I + +AGAG ++L+ + G G AI+G L Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 66.8 bits (163), Expect = 2e-13 Identities = 106/699 (15%), Positives = 207/699 (29%), Gaps = 99/699 (14%) Query: 125 KDASLSLDTRSFYLELTVNRAAMQAAILPRTNMLGESTAQN--LSSVLNYSMGSYYNKYE 182 DA+ LD L LT+ +A M + + +LNY+ + Sbjct: 143 HDATAQLDVGQQRLNLTIPQAFMS---NRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 183 ---NTDNASSYLTL-DNT--WSLR-EHHLNFNGSLYGIGTGNQESKLYRSMYERDYQGRR 235 N+ A L N W LR ++N S G+ N+ + ERD R Sbjct: 200 IGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW-LERDIIPLR 258 Query: 236 --LAMGMVDTWNLQSIASMSALNSSRIYGVSYGNKSSSQTQDNTLALVPVTVFLPA---- 289 L +G + G + D+ + F P Sbjct: 259 SRLTLG-------DGYTQGDIFDGINFRGAQLAS-------DDNMLPDSQRGFAPVIHGI 304 Query: 290 ---AGEVHVYRDGKLLSIQNFSMGSYELDTSRLPFGIYNVDIQVVV---NGRVVSSRTAN 343 +V + ++G + G + ++ + + D+QV + +G Sbjct: 305 ARGTAQVTIKQNGYDIYNSTVPPGPFTIND--IYAAGNSGDLQVTIKEADGSTQI----- 357 Query: 344 INKTFARKSSVT--GDLSWQTFGGSLEYNKMDYRHKY----NINYGTKNTWIAGIAAATS 397 ++ + G + G + +G W + Sbjct: 358 FTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLA 417 Query: 398 QPWLS---GVNLKTTLYG---FDT--------NGVNETEANVIFNDAFSFNQQGLLATDG 443 + + G+ G D + +V F S N+ G Sbjct: 418 DRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLV 477 Query: 444 SWQ-STSTFNMSLPDGYG--NLWGSRQYSSIGNALPMQQNDYVTIGAN------ANLRKI 494 ++ STS + + D + + + + DY + N + + Sbjct: 478 GYRYSTSGY-FNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQ 536 Query: 495 APFLGTLSVSRTNNKYTGSTYTNVDYDQSLLAN-RYATVSLRAGIQNYQYNNHENLRDKY 553 TL +S ++ Y G++ + + L +L + N + RD+ Sbjct: 537 LGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSY---SLTKNAWQKGRDQM 593 Query: 554 VNIDVSIPFSTWLSTGVSSQNGNMLANATLRKSFDDSAITQVGAS--------VSKQIKQ 605 + ++V+IPFS WL + SQ + A+ ++ + G +S ++ Sbjct: 594 LALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQT 653 Query: 606 NKNDDSRYRSDDYAANGYVSYDTKYNAGTVSVSRSSQHSSNYSLSSQGSLAWTEKNVYVG 665 S ++Y Y + S S G + V +G Sbjct: 654 GYAGGGDGNSGST-GYATLNYRGGYGNANIGYSHSDDIKQ-LYYGVSGGVLAHANGVTLG 711 Query: 666 KGTQTAGLVVNTNFSGKGRMMAQINGQNYPLT---GKSNFISLPPYAEYKVELMNDKNSE 722 + ++V G A++ Q T G + Y E +V L + Sbjct: 712 QPLNDTVVLVKA----PGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVAL-DTNTLA 766 Query: 723 DSVDIVNGRRNKVVLYPGNVSVINPEIKQLVTVFGRVKD 761 D+VD+ N VV G + + + + + + Sbjct: 767 DNVDLDNAVA-NVVPTRGAIVRAEFKARVGIKLLMTLTH 804
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.2 bits (218), Expect = 6e-23 Identities = 62/253 (24%), Positives = 101/253 (39%), Gaps = 8/253 (3%) Query: 3 RVVVITGGGTGIGAACPRLMRAAGDRVFITGRREAPLQAVADETGATA-----LVGDAAD 57 ++ ITG GIG A R + + G + L+ V A A D D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 GEVWRQRLLPAILDQTGGIDVLICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRAC 117 + + I + G ID+L+ AG + SD +W N T F + R+ Sbjct: 69 SAAIDE-ITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 LPSLIARR-GNVLFVASIASLAAGPQACGYVTAKHALIGLMRSVARDYGPQGVRANAVCP 176 ++ RR G+++ V S + Y ++K A + + + + +R N V P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 177 GWVTTPMADEEMRPLMQAEGLSLTEAYQRVCRDVPLRRPASPEEIAQASQFLCSPQAAII 236 G T M + + + + +PL++ A P +IA A FL S QA I Sbjct: 188 GSTETDM-QWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 237 SGATLVADGGASI 249 + L DGGA++ Sbjct: 247 TMHNLCVDGGATL 259
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 30.3 bits (68), Expect = 0.022 Identities = 10/23 (43%), Positives = 13/23 (56%) Query: 57 AEQKVQQLTQQQQQTQATTQQVA 79 + + QQ QQQQ QAT Q+ Sbjct: 338 PQAQQQQGQGQQQQAQATAQEAV 360
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 30.6 bits (69), Expect = 0.009 Identities = 23/130 (17%), Positives = 45/130 (34%), Gaps = 21/130 (16%) Query: 114 GETPLDEPISLSPPLSRVSLAAYCHKLNTFADLLLR------------DYDLQLAYHHHL 161 P+ E ++ L+ + L YC +LN F L + + Y + L Sbjct: 57 SSLPITE-VAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKRMISCQFTHPSKETYLYQL 115 Query: 162 ----MMLVEHDDELERFLSHTHDNVGLAFDTGHAFVAGVEIPRVLHKYGHRIRHLHLKDV 217 +L L + + + L F++ R+ +R+ LK Sbjct: 116 YASSNVL----QLLAFLIKNGSHSRPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLS 171 Query: 218 RPQVLGRLYR 227 + +++G YR Sbjct: 172 KNKIVGEEYR 181
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.030 Identities = 41/208 (19%), Positives = 76/208 (36%), Gaps = 14/208 (6%) Query: 44 SHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGVESTSAWSL 102 +H L + YA P+LG +DR G R ++ + + ++ + W L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YVALAIIICGY-GLFKSNISCLLGELYAHDDPRRDGGFSLLYAAGNVGSIAAPIACGLAA 161 Y + I+ G G + + ++ D+ R F + A G +A P+ GL Sbjct: 100 Y--IGRIVAGITGATGAVAGAYIADITDGDE--RARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHIGFALAGIGMFIGLMIFLSGSRHFRHT-RGVDKPALRAVKFVLPTWGWLLVMLC 220 + H F A + + FL+G + +G +P R L ++ W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLLQNNWSGYLLAIVCLFAAQ 248 +A + + A+ +F Sbjct: 212 VAALMAVFFIMQLVGQVPAALWVIFGED 239
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 34.4 bits (78), Expect = 0.004 Identities = 29/129 (22%), Positives = 44/129 (34%), Gaps = 7/129 (5%) Query: 10 AQFAAEAAVSAAEAKQYLIEVQQGYQDISATTQEAINAATAAEAAKSAAETAEQNSSTSA 69 AA+A++ AA A + +Q + +E A AA + A A N S A Sbjct: 206 TLTAAKASIEAAAANK---AREQAAAEAKRKAEEQARQQAAIRAANTYAMPA--NGSVVA 260 Query: 70 AASSESATAAAGSAAQAEEYADNASDYAQNKFTFYKTASDPDGTIAGLAATTDGQSFWVA 129 A+ A AA + +A S A L ++ W Sbjct: 261 TAAGRGLIQVAQGAASLAQAISDAIAVLGR--VLASAPSVMAVGFASLTYSSRTAEQWQD 318 Query: 130 QGPDALSAA 138 Q PD++ A Sbjct: 319 QTPDSVRYA 327
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.2 bits (68), Expect = 0.005 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 9/53 (16%) Query: 17 SLRSLIDTFNASVAPEDWIDTFYDLVFNIETCGDYGLMCWGKIVD---VERLL 66 SL + + FN A +W++T + L F+I G +GK+ D ++RLL Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLL 82
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 27.7 bits (61), Expect = 0.020 Identities = 10/37 (27%), Positives = 19/37 (51%) Query: 57 GFVYGDLPWTFHLAASSPSIKYIDNWQTTQMTTRSVL 93 G +G + W F +A S+ + + W+T + S+L Sbjct: 11 GLAFGLMAWPFGASAKGKSMVWNEQWKTPSFVSGSLL 47
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 28.9 bits (64), Expect = 0.010 Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 14/101 (13%) Query: 63 VPSGFVHRDGQASITIWLGQASMLIQPG--REITLMVAGDFWAKTSTAAT----RGQKVF 116 VP G+ H GQ +T LG +QPG R IT+ + + AT G K Sbjct: 250 VPDGYAHSSGQRVLTFTLGD----MQPGEHRTITVEFCPLKRGRATNIATVSYCGGHKNT 305 Query: 117 ASLTT--GE--VQVAAAGATVAGFIETAFYAASDCDAGELV 153 AS+TT E VQV+ AGA + + Y S + G+LV Sbjct: 306 ASVTTVINEPCVQVSIAGADWSYVCKPVEYVISVSNPGDLV 346
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 32.3 bits (73), Expect = 0.003 Identities = 18/70 (25%), Positives = 31/70 (44%) Query: 2 VVSDPAFLSTSKEKKIAGMFSIGGVMLQIETNKGDKGLDVTGLSSNKHEDETLLPRNAKM 61 V++ P F+STS F+ ++L+I K G ++ + E E LL +K Sbjct: 371 VITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKF 430 Query: 62 EVIGVHPPKS 71 ++ V K Sbjct: 431 KINKVDSYKD 440
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.029 Identities = 11/21 (52%), Positives = 15/21 (71%) Query: 34 FLNEISDIPIANKAYRLRVLQ 54 FL+EI D+P+ + LRVLQ Sbjct: 236 FLDEIGDMPMDAQTRLLRVLQ 256
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 30.6 bits (69), Expect = 4e-04 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 6/52 (11%) Query: 30 WFHGLDWNFIALASGVIIGVA-TYLTNLYFKRRWTKMYQ---QSLDRGYGGP 77 W G N +A+A G II + ++TN F+ K+++ L RG GGP Sbjct: 348 WNDGA--NVLAIAPGEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGP 397
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 29.4 bits (66), Expect = 0.025 Identities = 20/95 (21%), Positives = 34/95 (35%), Gaps = 14/95 (14%) Query: 60 GDGDKGSYKRNG---FDGGTRFRFAADYYLFDDISWISYYELGVNIPALFDWDNHYAEGA 116 +G + + G D G++ F L + + I E +I A Sbjct: 39 HNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQVEQKASI----------AGTD 88 Query: 117 NNTTRRMLYTGLKSDTWGTLTYGQQNSIYYDVVGV 151 + R + GLK +G L G+ NS+ D + Sbjct: 89 SGWGNRQSFIGLKGG-FGKLRVGRLNSVLKDTGDI 122
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.025 Identities = 13/28 (46%), Positives = 16/28 (57%) Query: 33 VKPRQTIALIGESGSGKSTLLAILAGLD 60 K ++ L G G GKSTL+ L GLD Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVGLD 620
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.9 bits (194), Expect = 2e-19 Identities = 47/212 (22%), Positives = 79/212 (37%), Gaps = 7/212 (3%) Query: 16 KTVLVTGCSSGIGLESALDLTRQGFRVLAA-CRKAEDVARMQELGLTG-----ILLDLDD 69 K +TG + GIG A L QG + A + + L D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PQSVERAAAEVIALTDNRLYGLFNNAGYGVYGPLNTISRQQMEQQFSANFFGAHQLTMLL 129 +++ A + + L N AG G ++++S ++ E FS N G + + Sbjct: 69 SAAIDEITARIEREMG-PIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMTPHGEGRIVMTSSVMGLIASPGRGAYAASKYALEAWSDALRMELRHSGIQVSLIEP 189 M G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 4e-05 Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 5/143 (3%) Query: 55 FSLTFVQIGMITLTFQLTSSLFQPVI-GYITDKRSMPWSLPVGMCFTLCGLILLALAGSF 113 F IG+ F + SL Q +I G + + +L +GM G ILLA A Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG 300 Query: 114 GMVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSLFQVGGNFGSSLGPLLAAVIIA 173 M L+ +G + ++R R G Q + S +GPLL I A Sbjct: 301 WMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 174 ---PYGKGNVAWFVLAALLAIVV 193 G AW AAL + + Sbjct: 361 ASITTWNG-WAWIAGAALYLLCL 382 Score = 32.1 bits (73), Expect = 0.004 Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 2/133 (1%) Query: 267 LHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYASLEWTGILTVIIG 326 L L+A + A + G + D+ GR+ V+ S+ G A ++ A W + I+ Sbjct: 49 LALYALMQFACAP--VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 327 FILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLLADHTSIDLVYKIC 386 I + + Y ++ G F FG G + VLG L S + Sbjct: 107 GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAA 166 Query: 387 AFLPLLGFLTIFL 399 A L L FLT Sbjct: 167 AALNGLNFLTGCF 179
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 30.4 bits (69), Expect = 0.005 Identities = 8/39 (20%), Positives = 22/39 (56%), Gaps = 2/39 (5%) Query: 488 ESLDKLADEVDESTKEAEKALEPFVERVKNLL--GDRVK 524 + + K+A+ + + K++ A++ V + L G++V+ Sbjct: 6 DLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQ 44
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 46.6 bits (110), Expect = 4e-07 Identities = 42/282 (14%), Positives = 95/282 (33%), Gaps = 4/282 (1%) Query: 31 RAADLPDRAEVQSQLNTLNKQKELTPQDKLVQQDLTQTLETLDKIERIKSETAQLRQQVE 90 + +DL + N +EL+ + ++++ E KI+ +++ A L + +E Sbjct: 72 KNSDLSFNNKALKDHND-ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALE 130 Query: 91 QAPAKLRQAVESLNNLSDVPNDDATRKTLSTLSLRQLESRVTQTLDDLQNAQNDLATYNS 150 A + L A RK +L + T ++ + + A + Sbjct: 131 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 190 Query: 151 QLVSLQTQPERVQNAMFNASQQLQQIRNRLNGTSVGD---ETLRPTQQVLLQAQQALLNA 207 + L+ E N S +++ + + E A A + Sbjct: 191 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 250 Query: 208 QIEQQRKSLEGNTILQDTLQKQRDYVTAWSNRLEHQLQLLQEAVNSKRLTLTEKTAQEAV 267 ++ L+ L+ ++ TA S +++ K + A Sbjct: 251 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 268 TPDETARIQANPLVKQELDINHQLSEKLIQATENGNQLVQRN 309 + A+ K++L+ HQ E+ + +E Q ++R+ Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 185 bits (470), Expect = 2e-61 Identities = 170/213 (79%), Positives = 194/213 (91%) Query: 1 MARKTKQQARETRQLILDVALRLFSQQGVSSTSLATIAKAAGVTRGAIYWHFKNKSDLFN 60 MARKTKQ+A+ETRQ ILDVALRLFSQQGVSSTSL IAKAAGVTRGAIYWHFK+KSDLF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSDASISDLEIEYRAKFPNDPLSVIREILVYVLEATVTEERRRLMMEIIYHKCEFV 120 EIWELS+++I +LE+EY+AKFP DPLSV+REIL++VLE+TVTEERRRL+MEII+HKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMTVVQQAQRQLSLASYERIEQTLKECIAAKLLPANLLTRRAAVLMRSYLSGLMENWLF 180 GEM VVQQAQR L L SY+RIEQTLK CI AK+LPA+L+TRRAA++MR Y+SGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APDSFDLHAEARDYVAILLEMYQFCPTLRGPES 213 AP SFDL EARDYVAILLEMY CPTLR P + Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPAT 213
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 4e-06 Identities = 29/210 (13%), Positives = 74/210 (35%), Gaps = 19/210 (9%) Query: 100 TYQASYDSAKGDLAKAQAAANMDQLTVKRYQKLLGTKYISQQDYDTAVATA-QQSNAAVV 158 + Y A +L ++ + + ++ Q + + +Q+ + Sbjct: 256 EQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV---TQLFKNEILDKLRQTTDNIG 312 Query: 159 AAKAAVETARINLAYTKVTSPISGRIGK-STVTEGALVQNGQTTALATVQQLDPIYVDVT 217 + + + +P+S ++ + TEG +V +T + V + D + V Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTAL 371 Query: 218 QSSNDFLRLKQEL-ADGRLKQENGK------AKVELVTNDGLKYPQSGTLEFSDVTVDQT 270 + D + A +++ KV+ + D ++ + G + +++++ Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEEN 431 Query: 271 TGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 S + I L GM V A ++ G Sbjct: 432 CLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 29.0 bits (65), Expect = 0.039 Identities = 17/78 (21%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 48 APLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFV-EGSDIQAGVSLYQIDPATYQASY 105 ++I G+ T + R E++P + I+ K V EG ++ G L ++ +A Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIV-KEIIVKEGESVRKGDVLLKLTALGAEADT 136 Query: 106 DSAKGDLAKAQAAANMDQ 123 + L +A+ Q Sbjct: 137 LKTQSSLLQARLEQTRYQ 154
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1365 bits (3535), Expect = 0.0 Identities = 805/1032 (78%), Positives = 911/1032 (88%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLSILKLPVAQYPTIAPPAISITAMYPGADAETVQNT 60 M NFFI RPIFAWV+AII+M+AG L+IL+LPVAQYPTIAPPA+S++A YPGADA+TVQ+T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDHLMYMSSNGDSTGTATITLTFESGTDPDIAQVQVQNKLALATPLLPQ 120 VTQVIEQNMNGID+LMYMSS DS G+ TITLTF+SGTDPDIAQVQVQNKL LATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKASSSFLMVVGVINTNGTMNQDDISDYVAANMKDPISRTSGVGDVQLFGS 180 EVQQQGISVEK+SSS+LMV G ++ N QDDISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMDPNKLNNFQLTPVDVISALKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW+D + LN ++LTPVDVI+ LK QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TNTEEFGNILLKVNQDGSQVRLRDVAKIELGGESYDVVAKFNGQPASGLGIKLATGANAL 300 N EEFG + L+VN DGS VRL+DVA++ELGGE+Y+V+A+ NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTANAIRAELAKMEPFFPSGMKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP GMK++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIQKGSHGATTGFFGWFNRMFDKSTHHYTDSVGNILRSTGRY 540 SVLVALILTPALCAT+LKP+ H GFFGWFN FD S +HYT+SVG IL STGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LVLYLIIVVGMAWLFVRLPSSFLPDEDQGVFLSMAQLPAGATQERTQKVLDEMTNYYLTK 600 L++Y +IV GM LF+RLPSSFLP+EDQGVFL+M QLPAGATQERTQKVLD++T+YYL Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKDNVESVFAVNGFGFAGRGQNTGIAFVSLKDWSQRPGEENKVEAITARAMGYFSQIKDA 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 MVFAFNLPAIVELGTATGFDFELIDQGGLGHEKLTQARNQLFGMVAQHPDVLTGVRPNGL 720 V FN+PAIVELGTATGFDFELIDQ GLGH+ LTQARNQL GM AQHP L VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYIMSEAKYRM 780 EDT QFK+++DQEKAQALGVS+SDIN T+ A GG+YVNDFIDRGRVKK+Y+ ++AK+RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDIGKWYVRGSDGQMVPFSAFSTSRWEYGSPRLERYNGLPSLEILGQAAPGKSTGEAM 840 LPED+ K YVR ++G+MVPFSAF+TS W YGSPRLERYNGLPS+EI G+AAPG S+G+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMEELAGKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV 900 ALME LA KLP+GIGYDWTGMSYQERLSGNQAPAL AIS +VVFLCLAALYESWSIP SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGVVGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGLI 960 MLVVPLG+VG LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLMEKEGKG++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATILAIFF 1020 EATL AVRMRLRPILMTSLAFILGV+PL IS+GAGSGAQNAVG GVMGGMV+AT+LAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVVRRRF 1032 VPVFFVV+RR F Sbjct: 1021 VPVFFVVIRRCF 1032
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.018 Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 120 PVGQLISRVTNDTEVIRDLYVTVVATVLRSAALIGAMLVAMFSLDWRMALVAIAIFPAVL 179 P G + + T ++ VV T+ + L+ +++ +F + R L+ P VL Sbjct: 318 PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLV-FLVMYLFLQNMRATLIPTIAVPVVL 376 Query: 180 IVMII 184 + Sbjct: 377 LGTFA 381
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.024 Identities = 11/64 (17%), Positives = 23/64 (35%), Gaps = 10/64 (15%) Query: 193 LAVLSQHLGFTLQECMAFGDAMNDREMLGSVGRGFIMGN----------AMPQLKAELPH 242 VL+Q L + +A + + ++ + +P++K P Sbjct: 16 RTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPD 75 Query: 243 LPVI 246 LPV+ Sbjct: 76 LPVL 79
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 116 bits (293), Expect = 4e-38 Identities = 49/88 (55%), Positives = 65/88 (73%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDALIASVTESLQAGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPGFRAGKALKDAV 89 NPQTG+EI I A+KVP F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.1 bits (75), Expect = 0.004 Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 12/144 (8%) Query: 137 KQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQK 196 ++ + L A QV R +++ ++ S+ +Q++A + Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK---KQLEAEHQ 333 Query: 197 ELGEMDDAPD-ENEALKRKIDAAKMPKEAKEKTEAELQKLKMMSPMS-AEATVVRGYIDW 254 +L E + + ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D Sbjct: 334 KLEEQNKISEASRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Query: 255 MVQVPWNARSKVKKDLRQAQEILD 278 + A+ +V+K L +A L Sbjct: 391 SRE----AKKQVEKALEEANSKLA 410
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.3 bits (89), Expect = 5e-05 Identities = 42/196 (21%), Positives = 75/196 (38%), Gaps = 15/196 (7%) Query: 221 RNNAWLI-LLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGMVNKTLGLFATILGALYG 279 R+N LI L ++ + + + ++++ + VN L +I A+YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 280 GVLMQRLTLFRALLIFGLLQGVSNAGYWLLSITDKHLYSMATAVFFENLCGGMGTAAFVA 339 L +L + R LL ++ S+ +S + + G G AAF A Sbjct: 71 K-LSDQLGIKRLLLFGIIINC-------FGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 340 LLM----TLCNKSFSATQFALLSALSAVGRVYVGP-IAGWFVEAHGWSTFYLFSVVAAVP 394 L+M K F L+ ++ A+G VGP I G WS L ++ + Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMG-EGVGPAIGGMIAHYIHWSYLLLIPMITIIT 181 Query: 395 GIALLLLCRQTLEHTQ 410 L+ L ++ + Sbjct: 182 VPFLMKLLKKEVRIKG 197
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 537 bits (1384), Expect = 0.0 Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 1 MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE 60 MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE Sbjct: 1 MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE 60 Query: 61 YEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGP 120 YEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGP Sbjct: 61 YEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGP 120 Query: 121 FKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNEN 180 FKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNEN Sbjct: 121 FKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNEN 180 Query: 181 EWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFDWGSDLGDDNFYDLNGKHARTSNSIASSH 240 EWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFDWGSDLGDDNFYDLNGKHARTSNSIASSH Sbjct: 181 EWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFDWGSDLGDDNFYDLNGKHARTSNSIASSH 240 Query: 241 ILALNYAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF 294 ILALNYAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF Sbjct: 241 ILALNYAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF 294
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 32.5 bits (74), Expect = 6e-04 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 7/66 (10%) Query: 3 RRADRLFQIVQILRGRRLTT-----AALLAERLGVSERTVYRDIRDLSLSGVPVEGEAGS 57 + R +I +I+ + T L + V++ TV RDI++L L V V GS Sbjct: 2 NKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIKELHL--VKVPTNNGS 59 Query: 58 GYRLLA 63 L Sbjct: 60 YKYSLP 65
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 342 bits (880), Expect = e-120 Identities = 101/308 (32%), Positives = 172/308 (55%), Gaps = 12/308 (3%) Query: 18 DFMRWDYWAFGISGFLLIVSIAIIGVRGFNWGLDFTGGTVIEITLEKPVDLDQMRDSLQK 77 DF RW + FG + ++I S+ + V G N+G+DF GGT I +D+ R +L+ Sbjct: 15 DFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALEP 74 Query: 78 AGFEEPQVQNFGSSR------DIMVRMPPVHDANGSQELGSKVVTVINE------STSQN 125 + + M+R+ D G++ G++ ++N+ + Sbjct: 75 LELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDPA 134 Query: 126 AAVKRIEFVGPSVGADLAQTGALALIAALVCILIYVGFRFEWRLAAGVVIALAHDVVITM 185 + E VGP V +L T +L+AA V I+ Y+ RFEW+ A G V+AL HDV++T+ Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 186 GVLSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQTL 245 G+ ++ ++ DLT VA+L+++ GYS+ND++VV DR+REN K + ++ N+S+ +TL Sbjct: 195 GLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETL 254 Query: 246 HRTLITSGTTLMVILMLFLFGGPILEGFSLTMLIGVSIGTASSIYVASALALKLGMKREH 305 RT++T TTL+ ++ + ++GG ++ GF M+ GV GT SS+YVA + L +G+ R Sbjct: 255 SRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNK 314 Query: 306 LIQQKVEK 313 + +K Sbjct: 315 EKKDPSDK 322
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 69.5 bits (170), Expect = 5e-15 Identities = 37/183 (20%), Positives = 88/183 (48%), Gaps = 5/183 (2%) Query: 422 IQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMIL-FYKKFGLIATSALIANLILIV 480 ++I ++GP + + + + + LA VV + ++ + F +F L A AL+ +++L V Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 481 GIMSLIPGATLTMPGIAGIVLTLAVAVDANVLINERIKEEL--SNGRTVQQAIDEGYRGA 538 G+ +++ + +A ++ +++ V++ +R++E L ++ ++ Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 539 FSSIFDANVTTLIKVIILYAVGTGAIKGFAITTGIGIATSMFTAIVGTRAIVNLLYGGKR 598 S +TTL+ ++ + G I+GF G+ T ++++ + IV L G R Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV-LFIGLDR 312 Query: 599 VKK 601 K+ Sbjct: 313 NKE 315
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 126 bits (318), Expect = 8e-35 Identities = 88/384 (22%), Positives = 157/384 (40%), Gaps = 15/384 (3%) Query: 8 LISVWFGCFFTGLAISQILPFLPLYVSQLGVTSHEALSMWSGLTFSVTFLVSAIVSPMWG 67 LI + + I I+P LP + L ++ G+ ++ L+ +P+ G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHY--GILLALYALMQFACAPVLG 64 Query: 68 SLADRKGRKLMLLRASLGMAIAILLQAFATNVWQLFILRAIMGLTSGYIPNAMALVASQV 127 +L+DR GR+ +LL + G A+ + A A +W L+I R + G+T A A +A Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 128 PRERSGWALSTLSTAQISGVIGGPLLGGFLADHVGLRMVFFITAILLTISFLVTLFLIKE 187 + +S G++ GP+LGG + FF A L ++FL FL+ E Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 188 GVRPQVSKSERLTGKQVFASLPYPGL---VISLFFTTLVIQLCNGSIGPILALF-IKSMA 243 + + + R AS + V +L ++QL + +F Sbjct: 184 SHKGE-RRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 244 PDSNNIAFLAGMIAAVPGVSALISAPRLGKLGDRIGTSRILLATLCCAVVMFFAMSFVTT 303 D+ I +AA + +L A G + R+G R L+ + + ++F T Sbjct: 243 WDATTIGI---SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATR 299 Query: 304 PLQLGTLRFLLGFADGAMLPAVQTLLLKYSSDSVTGRIFGYNQSFMYLGNVAGPLIGA-- 361 + LL G +PA+Q +L + + G++ G + L ++ GPL+ Sbjct: 300 GWMAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358 Query: 362 -SVSAMAGFRWVFIATAIIVFINL 384 + S W +IA A + + L Sbjct: 359 YAASITTWNGWAWIAGAALYLLCL 382
>SSPANPROTEIN#Salmonella invasion protein InvJ signature. Length = 336 Score = 31.2 bits (70), Expect = 0.006 Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 5/56 (8%) Query: 73 QDPARIALRPSTVT-LAQIPGREAQQLINAESGQPLAAIDVIFPIVHGTLGEDGSL 127 +D +++ L+P+T+ L+Q+ G + + + A+S + IFP G GED SL Sbjct: 212 KDVSQLPLQPTTIADLSQLTGGDEKMPLAAQSKPMMT----IFPTADGVKGEDSSL 263
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 29.6 bits (66), Expect = 0.005 Identities = 15/53 (28%), Positives = 25/53 (47%) Query: 44 GLEAGSEGFALLPELEQPAGALYVTKTACDAFYHTSLAQVLDEHDIQQFVICG 96 GL +G ++ EL L +TK AF T+L +++ + Q +I G Sbjct: 98 GLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITG 150
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.8 bits (69), Expect = 0.008 Identities = 18/69 (26%), Positives = 29/69 (42%) Query: 254 DILRDIRERSDLPLGAYQVSGEYAMIKFAAQAGAIDEEKVVLESLGAIKRAGADLIFSYF 313 + ++ + L L QV G A F +D E L I+ A +IF+ Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 314 ALDLAEKKI 322 L+L E++I Sbjct: 526 DLNLVERRI 534
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 29.7 bits (66), Expect = 0.014 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 4/38 (10%) Query: 39 WAVAALQLISPLFLPPPGQVLQKLITIAGPQGFMDATL 76 ++ A L LI+P FLP G+ L + +GP G TL Sbjct: 7 FSSATLALITPPFLPKGGKALSQ----SGPDGLASITL 40
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 29.1 bits (65), Expect = 0.018 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%) Query: 159 LWLLYRTRY--GMAIRAVAFDVNTVRLMGIDANRIISLVFALGSSLAALGGVFYSIS 213 L L+ R R MA+ + + +NT ID NRI++L + L ALG V Y ++ Sbjct: 4 LPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 536 bits (1381), Expect = 0.0 Identities = 225/384 (58%), Positives = 263/384 (68%), Gaps = 35/384 (9%) Query: 1 MKKSTLALMMMGFVASTATQAAEVYNKNANKLDVYGKIKAMHYFSDYDSKDGDQTYVRFG 60 MK+ LAL++ +A+ A AAE+YNK+ NKLD+YGK+ +HYFSD SKDGDQTY+R G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 IKGETQINDDLTGYGRWESEFSGNKTESDSSQ-KTRLAFAGVKLKNYGSFDYGRNLGALY 119 KGETQIND LTGYG+WE N TE + + TRLAFAG+K +YGSFDYGRN G LY Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGLVDGLDLTLQYQGKNE--- 176 DVE WTDM PEFGGDS DN+MT RA+G+ATYRNTDFFGLVDGL+ LQYQGKNE Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 177 -------------GREAKKQNGDGVGTSLSYDFGGSDFAVSAAYTSSDRTNDQNLLAR-- 221 G + + NGDG G S +YD G F+ AAYT+SDRTN+Q Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDI-GMGFSAGAAYTTSDRTNEQVNAGGTI 239 Query: 222 GQGSKAEAWATGLKYDANNIYLATMYSETRKMTP-------ISGGFANKAQNFEAVAQYQ 274 G KA+AW GLKYDANNIYLATMYSETR MTP GG ANK QNFE AQYQ Sbjct: 240 AGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQ 299 Query: 275 FDFGLRPSLGYVLSKGKDIE----GVGSEDLVNYIDVGLTYYFNKNMNAFVDYKINQLKS 330 FDFGLRP++ +++SKGKD+ +DLV Y DVG TYYFNKN + +VDYKIN L Sbjct: 300 FDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDD 359 Query: 331 DNKL----GINDDDIVALGMTYQF 350 D+ GI+ DDIVALGM YQF Sbjct: 360 DDPFYKDAGISTDDIVALGMVYQF 383
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.9 bits (88), Expect = 4e-05 Identities = 31/140 (22%), Positives = 53/140 (37%), Gaps = 20/140 (14%) Query: 119 DTLRALLDNSI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQPGLFTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMGTKLQAA-DVACRAG 228 D G + + +++V +++ + G MG K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAAGNRPDVIGHAMAG 248 IIA + A+ G Sbjct: 290 ERAIIAH---LEKAVEALEG 306 Score = 29.0 bits (65), Expect = 0.032 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAMGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.009 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 4/56 (7%) Query: 44 SKIVNVLEAPFAGTLRRILAREGETLQVGAVLALAADASVSDAELDEFVARLATAK 99 SK + +E ++ I+ +EGE+++ G VL A ++A+ + + L A+ Sbjct: 96 SKEIKPIEN---SIVKEIIVKEGESVRKGDVLLK-LTALGAEADTLKTQSSLLQAR 147
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (255), Expect = 2e-28 Identities = 73/253 (28%), Positives = 124/253 (49%), Gaps = 16/253 (6%) Query: 8 RTAIVTGGATGLGREFVLSLAKEGVNIC-FTYMREEEHPERLIETVKTSANVEIIAVKTD 66 + A +TG A G+G +LA +G +I Y E+ E+++ ++K A A D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL--EKVVSSLKAEARHAE-AFPAD 65 Query: 67 LSDEQSRENLFATCIDRLGKADILVNNAGIWLSGYVTEISPQDWDLVMNVNLKAIFHLSQ 126 + D + + + A +G DILVN AG+ G + +S ++W+ +VN +F+ S+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 LFVNHCLQHDQMGSILNITSQAAFHGSTTGHAHYAASKAGLVAFAISLAREVAKQKINVN 186 + + + GSI+ + S A T A YA+SKA V F L E+A+ I N Sbjct: 126 SVSKY-MMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 187 NIAVGIMDTAMIRKN-IEQNPDSYVSR---------IPVGRVAQPQEIADIGVFMVSPKT 236 ++ G +T M ++N V + IP+ ++A+P +IAD +F+VS + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 237 SYMTGATLDVTGG 249 ++T L V GG Sbjct: 244 GHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 62.5 bits (152), Expect = 8e-13 Identities = 79/388 (20%), Positives = 145/388 (37%), Gaps = 26/388 (6%) Query: 3 LALFALTIGAFAIGTTEFVIVGLVPTIAQQLSISLPSA---GLLVSIYALGVAIGAPVLT 59 + L + + A IG +I+ ++P + + L S G+L+++YAL APVL Sbjct: 9 VILSTVALDAVGIG----LIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 60 ALTGRMPRKQLLLALMVLFTAGNVLAWQAPGYETLILARLLTGLAHGVFFSIGSTIATSL 119 AL+ R R+ +LL + + AP L + R++ G+ G+ IA Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 120 VAKEKAASAIAIMFGGLTVALVTGVPFGTFIGQHFGWRETFLAVSILGVIALISSLILVP 179 E+A M +V G G +G F F A + L + ++ L+P Sbjct: 125 DGDERAR-HFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 180 NNIPGRASASLRDQMKVLTHPRLLMIYTITALGYGGVFTAF-------TFLAPMMQELAG 232 + G R+ + L R T+ A F ++ Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 233 FSPSAVSWILLGYGVSVAIGNVW-GGKLADKHGAVSALKFIFAALVVLLLVFQLTASVHY 291 + + + L +G+ ++ G +A + G AL A + A+ + Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGT-GYILLAFATRGW 301 Query: 292 AALATVLVMGIFAFGNVPGLQVYVVQKAEQYTPGAVDVASGLNIAAFNVGIALGSIVGGQ 351 A ++++ G +P LQ + ++ ++ G G A ++ +G ++ Sbjct: 302 MAFPIMVLLASGGIG-MPALQAMLSRQVDEERQGQ---LQGSLAALTSLTSIVGPLLFTA 357 Query: 352 TVERYGLAQTPWIG-AMIVLVALLLVVL 378 Y + T W G A I AL L+ L Sbjct: 358 I---YAASITTWNGWAWIAGAALYLLCL 382
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.8 bits (67), Expect = 0.009 Identities = 18/66 (27%), Positives = 24/66 (36%), Gaps = 14/66 (21%) Query: 120 AEAI-SLLRNNRVVILSAGTGNPFFTT-------------DSAACLRGIEIEADVVLKAT 165 AE I L+ +VI S G G P D A E+ AD+ + T Sbjct: 176 AETIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILT 235 Query: 166 KVDGVF 171 V+G Sbjct: 236 DVNGAA 241
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 48.0 bits (114), Expect = 1e-08 Identities = 33/174 (18%), Positives = 61/174 (35%), Gaps = 9/174 (5%) Query: 23 APRVITLSPANTELAFAAGITPVGVSSYSDY------PSQAKTIEQVASWQGMNLERIVA 76 R++ L EL A GI P GV+ +Y P ++ V NLE + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 77 LKPDVVLAWRG-GNAERQVNQLQSLGIHVLWVQTSTIEEIIATLRELAQWSPQPEKAQQA 135 +KP ++ G G + + ++ + +L E+A A+ Sbjct: 95 MKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETH 154 Query: 136 AQAMQQEYDALKARYANAPKKRVFL-QFGSAP-LFTSGPGSIQDQVLRLCGGEN 187 + ++K R+ + + L + GP S+ ++L G N Sbjct: 155 LAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPN 208
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 432 bits (1112), Expect = e-156 Identities = 214/291 (73%), Positives = 244/291 (83%) Query: 6 LITRRRLLIAMALSPLLWQMRGAQAADVDPQRVVALEWLPAELLLALGVTPYGVADIPNY 65 LI+RRRLL AMALSPLLWQM A AA +DP R+VALEWLP ELLLALG+ PYGVAD NY Sbjct: 6 LISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINY 65 Query: 66 RLWVNEPALPDSVIDVGLRTEPNLELLTQMKPSFIVWSAGYGPSPEKLARIAPGRGFTFS 125 RLWV+EP LPDSVIDVGLRTEPNLELLT+MKPSF+VWSAGYGPSPE LARIAPGRGF FS Sbjct: 66 RLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFS 125 Query: 126 DGKRPLAMAQRSLLEMADLLGKTQQAKRHLAEFDALMESLRPRFAGRGDRPLLMISLLDP 185 DGK+PLAMA++SL EMADLL A+ HLA+++ + S++PRF RG RPLL+ +L+DP Sbjct: 126 DGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDP 185 Query: 186 RHVLVFGENCLFQEVLDRFGIKNAWHGEAAFWGSVSVGIDRLAAFNEADVICFDHGNERD 245 RH+LVFG N LFQE+LD +GI NAW GE FWGS +V IDRLAA+ + DV+CFDH N +D Sbjct: 186 RHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKD 245 Query: 246 MAQLLATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFARVLADAQGSPA 296 M L+ATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHF RVL +A G A Sbjct: 246 MDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 214 bits (546), Expect = 4e-71 Identities = 100/266 (37%), Positives = 159/266 (59%), Gaps = 7/266 (2%) Query: 17 KLLPQIVTLIILITAIPQLAKLTWRVVFPVSPEDISALPLTMPPAADPELKNVRPAFTLF 76 ++ +I+ ++++ QLA + WR+ P ++ + + PA + FTLF Sbjct: 12 SVIRRILFYLLMLLFCQQLAMIFWRIGLP---DNAPVSSVQITPAQARQQPVTLNDFTLF 68 Query: 77 GLAV-KNSPTPTDAASLNQVPVSSLKLRLAGLLASSNPARSIAIIEKGNQQVSLSTGDPL 135 G++ KN DA+ ++ +P S+L L L G++A + +RSIAII K N+Q S + + Sbjct: 69 GVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEV 128 Query: 136 PGYDARIAAILPDRIIVNYQGRKEAILLFNDSRAPSPPPTAAGNPPLVKRLREQPQNILT 195 PGY+A+I +I PDR+++ YQGR E + L++ + S G + + + Sbjct: 129 PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVP--GAQVNEQLQQRASTTMSD 186 Query: 196 YLSISPVLSGDKLLGYRLNPGKDASLFRQSGLQANDLAIALNGIDLRDQEQAQQALQNLA 255 Y+S SP+++ +KL GYRLNPG + F + GLQ ND+A+ALNG+DLRD EQA++A++ +A Sbjct: 187 YVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMA 246 Query: 256 DMTEITLTVEREGQRHDIAFAL-GDE 280 D+ TLTVER+GQR DI GDE Sbjct: 247 DVHNFTLTVERDGQRQDIYMEFGGDE 272
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 838 bits (2167), Expect = 0.0 Identities = 606/646 (93%), Positives = 631/646 (97%) Query: 10 ALLILTPLLFSPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDML 69 LLI LLF PAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDML Sbjct: 13 TLLIFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDML 72 Query: 70 NEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRAKDAKTSAVPVASAAAPGEGDEVVTRVV 129 NEEQYYQFFLSVLDVYGFAVINMNNGVLKVVR+KDAKT+AVPVAS AAPG GDEVVTRVV Sbjct: 73 NEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVV 132 Query: 130 PLTNVAARDLAPLLRQLNDNAGAGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDR 189 PLTNVAARDLAPLLRQLNDNAG GSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDR Sbjct: 133 PLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDR 192 Query: 190 SVVTVPLSWASAAEVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRI 249 SVVTVPLSWASAA+VVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRI Sbjct: 193 SVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRI 252 Query: 250 IAMIKQLDRQQAVQGNTKVIYLKYAKAADLVEVLTGISSSLQSDKQSARPVAAIDKNIII 309 IAMIKQLDRQQA QGNTKVIYLKYAKA+DLVEVLTGISS++QS+KQ+A+PVAA+DKNIII Sbjct: 253 IAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIII 312 Query: 310 KAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN 369 KAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN Sbjct: 313 KAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN 372 Query: 370 AGMTQFTNSGLPISTAIAGANQYNKDGTISSSLASALGSFNGIAAGFYQGNWAMLLTALS 429 AGMTQFTNSGLPISTAIAGANQYNKDGT+SSSLASAL SFNGIAAGFYQGNWAMLLTALS Sbjct: 373 AGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALS 432 Query: 430 SSTKNDILATPSIVTLDNMQATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKP 489 SSTKNDILATPSIVTLDNM+ATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKP Sbjct: 433 SSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKP 492 Query: 490 QINEGDAVLLEIEQEVSSVADSASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKT 549 QINEGD+VLLEIEQEVSSVAD+ASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDK+ Sbjct: 493 QINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKS 552 Query: 550 VTDTADKVPLLGDIPVIGALFRSDSKKVSKRNLMLFIRPTIIRDRDEYRQASSGQYTAFN 609 V+DTADKVPLLGDIPVIGALFRS SKKVSKRNLMLFIRPT+IRDRDEYRQASSGQYTAFN Sbjct: 553 VSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFN 612 Query: 610 NAQTKQRGKESSEASLSNDLLHIYPQQETQAFRQVSAAIDAFNLGG 655 +AQ+KQRGKE+++A L+ DLL IYP+Q+T AFRQVSAAIDAFNLGG Sbjct: 613 DAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFRQVSAAIDAFNLGG 658
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 508 bits (1311), Expect = 0.0 Identities = 277/407 (68%), Positives = 334/407 (82%), Gaps = 4/407 (0%) Query: 1 MALFRYQALDAQGKTRRGLQQADSARHARQLLRDKGWLALEVTTADPARRLWAGGSLT-- 58 MA + YQALDAQGK RG Q+ADSAR ARQLLR++G + L V ++ L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 59 --RRTSAGDLALLTRQLATLVAAGIPLEKALDAVAQQCEKPSLRTLMAGVRSKVLEGHSL 116 R S DLALLTRQLATLVAA +PLE+ALDAVA+Q EKP L LMA VRSKV+EGHSL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 AEAMRAYPACFDGLFYAMVAAGETSGHLDGVLNRLADYTEQRQQLRARLLQAMIYPIVLT 176 A+AM+ +P F+ L+ AMVAAGETSGHLD VLNRLADYTEQRQQ+R+R+ QAMIYP VLT Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 177 LVAISVIAILLSTVVPKVVEQFVHLKQALPFSTRLLMSLSDIVRSAGPWLALLSLLALLA 236 +VAI+V++ILLS VVPKVVEQF+H+KQALP STR+LM +SD VR+ GPW+ L L +A Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 237 LRYLLRQPARRLAWDRALLRLPVIGRVARSVNSARYARTLSILNASAVPLLLSMRISADV 296 R +LRQ RR+++ R LL LP+IGR+AR +N+ARYARTLSILNASAVPLL +MRIS DV Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 297 LSNAWARSQLAAASESVREGVSLHRALESTALFPPMMRYMIASGEQSGELTAMLERAAEN 356 +SN +AR +L+ A+++VREGVSLH+ALE TALFPPMMR+MIASGE+SGEL +MLERAA+N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 357 QDRELSAQIQMALSLFEPLLVVTMAGMVLFIVLAILQPILQLNTLMS 403 QDRE S+Q+ +AL LFEPLLVV+MA +VLFIVLAILQPILQLNTLMS Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 243 bits (621), Expect = 2e-86 Identities = 98/140 (70%), Positives = 112/140 (80%) Query: 1 MQRQRGFTLLEIMVVIVILGILASLVVPNLMGNKEKADRQKVVSDLVALEGALDMYKLDN 60 +QRGFTLLEIMVVIVI+G+LASLVVPNLMGNKEKAD+QK VSD+VALE ALDMYKLDN Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 SRYPNTEQGLQALVTAPAAEPHARNYPEGGYIRRLPQDPWGNEYQLLSPGQHGAIDVFSV 120 YP T QGL++LV AP P A NY + GYI+RLP DPWGN+Y L++PG+HGA D+ S Sbjct: 64 HHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSA 123 Query: 121 GPDGMPDTNDDIGNWTLGKK 140 GPDG T DDI NW L KK Sbjct: 124 GPDGEMGTEDDITNWGLSKK 143
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 178 bits (452), Expect = 6e-60 Identities = 99/164 (60%), Positives = 126/164 (76%) Query: 1 MSQRGFTLLEMMLVLLLIGVSASMVLLAFPSARTQEATQILARFQAQLDFVRERGQQTGQ 60 M QRGFTLLEMML+LLL+GVSA MVLLAFP++R A Q LARF+AQL FV++RG QTGQ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 61 LFGIIIHPERWQFMRLQPADDSAPAAADDRWGNAQWLPLQAGRVTTAETLPRARLTLRFP 120 FG+ +HP+RWQF+ L+ D + PA ADD W +WLPL+AGRV T+ ++ +L L F Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNLAFA 120 Query: 121 DGQAWTPGEQPDVLIFPGGEVTPFQLRIDAAMGINVDAQGDSQP 164 G+AWTPG+ PDVLIFPGGE+TPF+L + A GI +A+G+S P Sbjct: 121 QGEAWTPGDNPDVLIFPGGEMTPFRLTLGEAPGIAFNARGESLP 164
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 2e-04 Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 8/99 (8%) Query: 1 MKREAGMTLIEVMVALVIF-ALAGLAV---MQSTLQQTRQLGRMEEKILASWLADNQLVQ 56 ++ G TL+E+MV +VI LA L V M + + +Q + L + L +L Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 57 LRLEKRWPALS--WSETTVEAAGTRWFVRWQGVETALPQ 93 L T+ + +G LP Sbjct: 64 HHYPTTNQGLESLVEAPTLPPLAANY--NKEGYIKRLPA 100
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.6 bits (74), Expect = 4e-04 Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 5/61 (8%) Query: 6 RGFTLIETLLALAILAVLSAAAV-MVLQNVIRADGLTREKSQ-QIAALQRAFRQIADDVT 63 RGFTL+E ++ + I+ VL++ V ++ N +AD ++K+ I AL+ A D Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKAD---KQKAVSDIVALENALDMYKLDNH 64 Query: 64 H 64 H Sbjct: 65 H 65
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 271 bits (694), Expect = 2e-93 Identities = 138/277 (49%), Positives = 167/277 (60%), Gaps = 15/277 (5%) Query: 1 MTTLAALSLHFPFVWYGFLLLFGLALGSFYNVVIYRLPRML---------------TQTA 45 M L L+ P++++ + LF L +GSF NVVI+RLP ML + Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGV 60 Query: 46 DDERITLSTPGSSCPQCRQPIAWRDNIPLLSFLWLGRRARCCQAPIAWSYPLTELATGLL 105 D+ L P S CP C PI +NIPLLS+LWL R R CQAPI+ YPL EL T LL Sbjct: 61 DEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALL 120 Query: 106 FILAGALLAPGLPLAGGLVLLSFLLILARIDARTQLLPDRLTLPLLWAGLLFNLNEVYIA 165 + LAPG L+L L+ L ID LLPD+LTLPLLW GLLFNL +++ Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVS 180 Query: 166 LPDAVAGAMAGYLALWSVYWLFRLLTGKEALGYGDFKLLAALGAWCGWQVLPQVLLLASA 225 L DAV GAMAGYL LWS+YW F+LLTGKE +GYGDFKLLAALGAW GWQ LP VLLL+S Sbjct: 181 LGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSL 240 Query: 226 SGLVWTLLQRLWTRQSLQQPLAFGPWLALAGGSIFLW 262 G + L +P+ FGP+LA+AG LW Sbjct: 241 VGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLW 277
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 71.9 bits (176), Expect = 5e-17 Identities = 53/246 (21%), Positives = 108/246 (43%), Gaps = 4/246 (1%) Query: 5 WVALKSIWTKEIHRFMRIWVQTLVPPVITMTLYFVIFGNLIGSRIGEMHGFTYMQFIVPG 64 W+A +W + + + + +L+ + +Y G +G +G + G +Y F+ G Sbjct: 16 WIA---VWRRNYIAWKKAALASLLGHLAEPLIYLFGLGAGLGVMVGRVGGVSYTAFLAAG 72 Query: 65 LIMMAVITNA-YANVASSFFSAKFQRNIEELLVAPVPTHVIIAGYVGGGVARGLCVGILV 123 ++ + +T A + + ++F + QR E +L + I+ G + + G + Sbjct: 73 MVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGI 132 Query: 124 TAVSLFFVPFQVHSWLFVALTLLLTAVLFSLAGLLNAVFAKTFDDISLIPTFVLTPLTYL 183 V+ Q S L+ + LT + F+ G++ A ++D T V+TP+ +L Sbjct: 133 GVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFL 192 Query: 184 GGVFYSLTLLPPFWQGLSHLNPIVYMISGFRFGFLGINDVPLATTFAVLVVFIVAFYLLC 243 G + + LP +Q + P+ + I R LG V + L ++IV + L Sbjct: 193 SGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLS 252 Query: 244 WSLIQR 249 +L++R Sbjct: 253 TALLRR 258
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 3e-05 Identities = 57/343 (16%), Positives = 112/343 (32%), Gaps = 8/343 (2%) Query: 60 VTGFLSDRFGRKPFIYLGILSYLIFFVGILLTKNIYLAYVFGIMAGLANSFLDSGTYPAL 119 V G LSDRFGR+P + + + + + + +++ Y+ I+AG+ + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 120 MESFPHSASRANVLIKAFVSAGQFLLPFIISFLIWANLWFGWSFVIAAALFVLSGIYLLK 179 + +R + A G P + + F AAAL L+ + Sbjct: 122 DITDGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 180 MPFPDSQAAKKEEAPTAQAETAVRPQANK-LDMVIFTLYGYIGMATFYLVSQWL-AQYGQ 237 + P+S ++ + + + +V + + M V L +G+ Sbjct: 180 L-LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 238 FVVGL-PYASAIKLLSIYTVGSLVCVFVTAAFVKEVFSSAIAMIIYTGLSMISLLLVCLF 296 I L + + SL +T + M+ +LL Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 297 PTPMMVTGFAFVIGFAAAGGVLQLGATIMAMSFPNGKGKATGIFYTAGSIASFTIPLITA 356 M + LQ A + +G+ G S+ S PL+ Sbjct: 299 RGWMAFPIMVLLASGGIGMPALQ--AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356 Query: 357 KLSQISIASIMWFDFLIAVIGFVIALYIGYRQLQARAAQKVSR 399 + SI + + ++ +++ L R L + A Q+ R Sbjct: 357 AIYAASITTWNGWAWIAGAALYLLCLPALRRGLWSGAGQRADR 399
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 61.0 bits (148), Expect = 3e-12 Identities = 71/415 (17%), Positives = 132/415 (31%), Gaps = 46/415 (11%) Query: 30 LSVGTMINYLDRTILGI---VAPQLSKEIHID---PAMMGIIFSAFAWTYALAQIPGGMF 83 L V LD +G+ V P L +++ A GI+ + +A G Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 84 LDRFGNKVTYALSIFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFP 143 DRFG + +S+ ++ + + L L + R+ G++ A ++ Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGAT-GAVAGAYIADITD 125 Query: 144 QHERARA----TATYTVGEYIGLAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRF 199 ERAR +A + G G P+L ++ FF L L L Sbjct: 126 GDERARHFGFMSACFGFGMVAG-----PVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180 Query: 200 YHEPHESRTANQAELEYIGASSINNKIQNVPFNWRDARRLLGCRQILGASLGQFAGNTTL 259 E H+ +N F W ++ + + Sbjct: 181 LPESHKGERRPLRREA------LNPLAS---FRWARGMTVVAALMAVFFIMQLVGQ---- 227 Query: 260 VFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKL 319 + + + H +G + L I+ + R G Sbjct: 228 -VPAALWVIFGEDRFHWDATTIGISLA---AFGILHSLAQAMITGPVAARLGERRA---- 279 Query: 320 PIISGLLLSSC--IIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDIAPENMAGLTG 377 ++ G++ I+ A I++ +A G GM L ++S E G Sbjct: 280 -LMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQ-AMLSRQVDEERQGQLQ 337 Query: 378 GIFNFCANMASIIAPLIIGVIISATGNFFYALIYVGLTALIGVIAYIFIIGDIKR 432 G ++ SI+ PL+ I +A+ + G + G Y+ + ++R Sbjct: 338 GSLAALTSLTSIVGPLLFTAIYAAS-----ITTWNGWAWIAGAALYLLCLPALRR 387
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.002 Identities = 41/187 (21%), Positives = 67/187 (35%), Gaps = 17/187 (9%) Query: 16 AAFMLVAFMMGVAGALQAPTLSLFLSREVGAQPFWVGLFYTVNAIAGILVSLWLAKRSDS 75 AA M V F+M + G + A +F +G+ I L + + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 76 RGDRRRLIMFCCLMAVGNALLFAFNRHYLTLITCGVMLASIANAAMPQLFALAREYADSS 135 R RR +M + +L AF V+LAS MP L A+ D Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG-IGMPALQAMLSRQVDEE 331 Query: 136 AREVVMFSSVMRAQLSLAWVIGPPLAFMLALNYGFTTMFSIAAG-----IFVISLALIAI 190 + + S SL ++GP L FT +++ + ++ AL + Sbjct: 332 RQGQLQGSLAALT--SLTSIVGPLL---------FTAIYAASITTWNGWAWIAGAALYLL 380 Query: 191 KLPSVPR 197 LP++ R Sbjct: 381 CLPALRR 387
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 36.5 bits (84), Expect = 2e-04 Identities = 17/81 (20%), Positives = 30/81 (37%), Gaps = 2/81 (2%) Query: 367 YHAGEHYQ-GNWFPAYGLLPRWHHASNHACEKPAGLETVTLTYYRDHVEHRVIGGIMRDL 425 YH G +YQ +F Y L + + E ++ + HR++GG + Sbjct: 180 YHVGLNYQNSGFFAQYAGLFQRYGEGTKKIEYDDQTYSIPSLFVEKLQVHRLVGGYDNNA 239 Query: 426 LTAHQVKLEIQELEYDAWHRG 446 L V + Q+ + G Sbjct: 240 LYV-SVAAQQQDAKLYGAMSG 259
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 27.8 bits (62), Expect = 0.048 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%) Query: 95 RALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPL 154 R LEK + Q + +L G + + PM+A + +L AK ++ LL + Sbjct: 362 RLCLEKQDIFRTQ--LRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGV 419 Query: 155 YFLPGILAGAAIDIPA 170 I G ++IP+ Sbjct: 420 DVSDSIEVGIMVEIPS 435
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 47.6 bits (113), Expect = 1e-09 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 62 DEATLFNIAVDPAYQRRGLGRALLEHVIDEVEKLGVVTLWLEVRASNVAAIALYESVGFN 121 A + +IAV Y+++G+G ALL I+ ++ L LE + N++A Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 122 EATIRRNYYP-TADGREDAI 140 + Y E AI Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 372 bits (955), Expect = e-133 Identities = 171/262 (65%), Positives = 209/262 (79%) Query: 1 MAWRSLPLSDELIWRAPLPTAEHALAESIREKIATLRPHLLDFLRLDEPAPRHALTLAEW 60 MA+RS PL +++IWR L + LA+++R IA R HLL+F+RLDEPAP +A+TLA+W Sbjct: 1 MAYRSAPLYEDVIWRTHLQPQDPTLAQAVRATIAKHREHLLEFIRLDEPAPLNAMTLAQW 60 Query: 61 SQPIALRSLLATWSDHIYRHQPTLPREQKPLLSLWAQWYIGLLVPPLMLALLNEPQGLSL 120 S P L SLLA +SDHIYR+QP + RE KPL+SLWAQWYIGL+VPPLMLALL + + L + Sbjct: 61 SSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDV 120 Query: 121 APEHFHVEFHESGRAACFWIDVHSDADIERLSPQARMDALVTRTLQPVVEALAATGEINS 180 +PEHFH EFHE+GR ACFW+DV D + SPQ RM+ L+++ L PVV+AL ATGEIN Sbjct: 121 SPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEING 180 Query: 181 KLIWSNTGYLINWYLGEMRALLGDERLAALRQHCFFEKQLADGQDNPLWRTVMLREGQLV 240 KLIWSNTGYLINWYL EM+ LLG+ + +LR FFEK L +G+DNPLWRTV+LR+G LV Sbjct: 181 KLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTNGEDNPLWRTVVLRDGLLV 240 Query: 241 RRTCCQRYRLPDVQQCGDCTLK 262 RRTCCQRYRLPDVQQCGDCTLK Sbjct: 241 RRTCCQRYRLPDVQQCGDCTLK 262
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 35.2 bits (80), Expect = 2e-04 Identities = 15/38 (39%), Positives = 23/38 (60%) Query: 239 PQYEETLMSIAQKLKQEGRQQGRLEGREEGHLEGLQEG 276 P E+ L + + ++G Q G EGR++GH +G QEG Sbjct: 38 PSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEG 75 Score = 29.0 bits (64), Expect = 0.023 Identities = 12/22 (54%), Positives = 17/22 (77%) Query: 255 EGRQQGRLEGREEGHLEGLQEG 276 EGRQQG +G +EG +GL++G Sbjct: 62 EGRQQGHKQGYQEGLAQGLEQG 83
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 49.7 bits (119), Expect = 2e-08 Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 17/106 (16%) Query: 3 VDWLFKNVTVIDGSGGPQYRADVAVKGDRIMAIAPA--------LDV---AAEQVIDGQG 51 VD + N ++D G +AD+ +K RI AI A + + +VI G+G Sbjct: 68 VDTVITNALILDHWG--IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEG 125 Query: 52 RVLAPGFIDVHTHDDINVIRMPEYLPKLSQGVTTVIVGNCGISAAT 97 +++ G +D H H I ++ E L G+T ++ G G + T Sbjct: 126 KIVTAGGMDSHIH-FICPQQIEE---ALMSGLTCMLGGGTGPAHGT 167
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 31.3 bits (71), Expect = 0.004 Identities = 30/173 (17%), Positives = 56/173 (32%), Gaps = 39/173 (22%) Query: 78 QIKQLLDVGAQT---LLVPMVQNAEEARLAVRATRYPPAGIRGVGSALARASRWNRVPDY 134 Q++ LL ++ PM+ EE R A + + G ++ + Sbjct: 374 QLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVG----- 428 Query: 135 IHRANDAMCVLVQIETREALKNLPQILDVDGVDGVFIGPADL----------SADMGHGG 184 + +E VD IG DL + + + Sbjct: 429 -----------IMVEIPSTAVAANLFAKE--VDFFSIGTNDLIQYTMAADRMNERVSYLY 475 Query: 185 NPQHPEVQAAIEDAIQQIRQAGKAPGIL--MANEQLAKRYLELGALFVAVGVD 235 P HP + ++ I+ GK G+ MA +++A L + +G+D Sbjct: 476 QPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIP------LLLGLGLD 522
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.009 Identities = 29/166 (17%), Positives = 58/166 (34%), Gaps = 9/166 (5%) Query: 140 RLKNLSEADRQNFFASEEARRAVHILLIANVSQSYFNQRLAAAQLQVANDTLQNYQQSYA 199 A + A + A A L + + +A+++ + A Sbjct: 204 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 263 Query: 200 FVEKQLLTGSTTVLALEQARSMIESTRADIAKRQGQLAQANNALQLLLGSYQHLPDDSAS 259 +EK L + + I++ A+ A + + A + Q+L + Q L D + Sbjct: 264 ELEKAL---EGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDA 320 Query: 260 SAVDLQGVTLPPSLSSAILLQRPDILEAEHSLQAANANIGAARAAF 305 S + + L ++ I EA S Q+ ++ A+R A Sbjct: 321 SREAKKQL----EAEHQKLEEQNKISEA--SRQSLRRDLDASREAK 360
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 688 bits (1777), Expect = 0.0 Identities = 224/1059 (21%), Positives = 437/1059 (41%), Gaps = 54/1059 (5%) Query: 1 MIEWIIRRSVANRFLVMMAALFLSIWGTWTIIHTPVDALPDLSDVQVIVKTRYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V V YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTWPLTTTMLSVPGARTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAEMGP-DATGVGWVFEYALVDRSGKHDLAELRSLQDWFLKYELKTIPNVSEVA 178 LP V + + + ++ V + ++ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQIVVDPMKLTQYGISLGEVKSALDASNQEAGGSSVELA------EAEYMVR 232 G +I +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFKNIVLKTGDNGVPVYLGDVARVQIGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ +G V L DVARV++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVISAVKEKLASLQSSLPEGVEVVTTYDRSQLIDRAIDNLSYKLLEEFIVVALV 352 +G NA + A+K KLA LQ P+G++V+ YD + + +I + L E ++V LV Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCFAFIMMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWEHQHPGEKLSNDTRWKIITEASVEVGPALFISLLIITLSFIPIFTLEGQEG 472 N + + E + P + ++ ++ AL ++++ FIP+ G G Sbjct: 415 NVERVMME-DKLPP---------KEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 473 KLFGPLAFTKTWSMAGAALLAIVAIPILMGFWIRGRIPAENSNPLNRF----------LI 522 ++ + T +MA + L+A++ P L ++ AE+ F + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPV-SAEHHENKGGFFGWFNTTFDHSV 523 Query: 523 RIYHPLLLKVLHWPKTTLLIALLSILTVVWPLNRVGGEFLPQINEGDLLYMPSTLPGISA 582 Y + K+L LLI L + +V R+ FLP+ ++G L M G + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 583 AQAADMLQKTDKLIMA--VPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQW-RPG 639 + +L + + V VF G + + + LKP ++ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDE 640 Query: 640 MTMEKIVDELDKTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTNLADIDAIAGQ 699 + E ++ + + + +++ + I +G + Q Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 700 IEGVARSVPG-VTSALAERLVGGRYLDIDIQREKAARYGMTVGDVQLFVSSAIGGAMVGE 758 + G+A P + S L +++ +EKA G+++ D+ +S+A+GG V + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 759 TVEGVERYPINIRYPQSYRDSPETLRQLPILTPLKQQIVLGDVAEVKVVTGPSMLKTENA 818 ++ + ++ +R PE + +L + + + + V G L+ N Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 819 RPTSWIYIDARDRDMVSVVHDLQQAIGKEVKLKPGISVSYSGQFELLERANQKLKLMVPM 878 P+ I +A L + + KL GI ++G + + +V + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENL--ASKLPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 879 TLMIIFVLLYLAFRRVGEALLIITSVPFALVGGIWFLYWMGFHLSVATGTGFIALAGVAA 938 + +++F+ L + + ++ VP +VG + V G + G++A Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 939 EFGVVMLMYLRHAIEAEPSLENPQTFSVDKLDEALYQGAVLRVRPKAMTVAVIIAGLLPI 998 + ++++ + + +E E + EA +R+RP MT I G+LP+ Sbjct: 939 KNAILIVEFAKDLMEKEGK----------GVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 999 LWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037 GAGS + + ++GGM++A LL++F +P + + Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 233 bits (595), Expect = 1e-81 Identities = 85/151 (56%), Positives = 111/151 (73%), Gaps = 1/151 (0%) Query: 25 PKGVQPISGFDASRYLGKWYEVARLENRFERGLEQVTATYGARSDGGISVVNRGYDPVKK 84 P+ V+P+S F+ + YLGKWYEVARL++ FERGL QVTA Y R+DGGISV+NRGY K Sbjct: 20 PESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKG 79 Query: 85 RWNESDGKAYFTGAPTTAALKVSFFGPFYGGYNVIRLD-DDYQYALVSGPNRDYLWILSR 143 W E++GKAYF T LKVSFFGPFYG Y V LD ++Y YA VSGPN +YLW+LSR Sbjct: 80 EWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDRENYSYAFVSGPNTEYLWLLSR 139 Query: 144 TPTIPAAVKQDYLNTARELGFDVDRLVWIRQ 174 TPT+ + ++ ++E GFD +RL++++Q Sbjct: 140 TPTVERGILDKFIEMSKERGFDTNRLIYVQQ 170
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 61.6 bits (149), Expect = 2e-13 Identities = 51/233 (21%), Positives = 85/233 (36%), Gaps = 16/233 (6%) Query: 4 VLITGASSGIGAGLAKSFAADGHLVIACGRDASRLAALQQLSPNISVRL-----FDMTDR 58 ITGA+ GIG +A++ A+ G + A + +L + S R D+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS-SLKAEARHAEAFPADVRDS 69 Query: 59 DACRQALTGCFA-----DLIILCAGTCEYLDHGQVDAALVERVMATNFLGPVNCLAALQT 113 A + D+++ AG + E + N G N ++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 114 QLEA--GDRVVLVSSMAHWLPFPRAEAYGASKAALTWFANSLRLDWEPKGVAVTVVSPGF 171 + +V V S +P AY +SKAA F L L+ + +VSPG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 172 VDTPLTRKNDFAMPGRVSVDRAVAA-IRHGLAKGKNHIAFPTGFSLALRLLAS 223 +T + G V + + G+ K +A P+ + A+ L S Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKK--LAKPSDIADAVLFLVS 240
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 25.8 bits (56), Expect = 0.037 Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 18 VACAWLTLCERQHRYPHLTLDALESAIATELEGFY--LRQHGEEKGRLI 64 VAC W+ +CE ++ PH +E+ I+ L L GE G+LI Sbjct: 135 VACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEINGKLI 183
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 30 VVLVGPSGCGKSTLLRLLAGLEPVSEGQIWLHD 62 VVL G G GKSTL+ L GL+ S+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT 631
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 40.5 bits (94), Expect = 9e-06 Identities = 85/307 (27%), Positives = 133/307 (43%), Gaps = 36/307 (11%) Query: 120 LQKEFWPAMHKNAQVMGTTYAIPFHNSTPILYYNKTMFDQAGIKQPPQTWAELLADAKKL 179 Q + +P + G A P L YNK + + PP+TW E+ A K+L Sbjct: 111 FQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDL-----LPNPPKTWEEIPALDKEL 165 Query: 180 TDESKGQWGIMLPSTNDDYGGWIFSALVRANGG---KYFNEDYP-GEVYYNSPTAIGALR 235 ++KG+ +M + + Y W L+ A+GG KY N Y +V ++ A L Sbjct: 166 --KAKGKSALMF-NLQEPYFTW---PLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLT 219 Query: 236 FWQDLIYKDKVMPSGVLNSKQISAAFFSGKLGMAMLSTGALGFMRENSKDFELGVAMLPA 295 F DLI K+K M + + AAF G+ M + G + ++ GV +LP Sbjct: 220 FLVDLI-KNKHMNADT-DYSIAEAAFNKGETAMTI--NGPWAWSNIDTSKVNYGVTVLPT 275 Query: 296 -KEQRAVPIGGASLVSFKGINEA--QKKAAYQFL-TYLVSPEVNGAWSRFTGYFSPRKAS 351 K Q + P G V GIN A K+ A +FL YL++ E A ++ + S Sbjct: 276 FKGQPSKPFVG---VLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKS 332 Query: 352 YDTPEMKAYLQQDPRAAIALEQLKYAHPWYSTWETVAVRKAMENQLAAVVNDA--KVTPE 409 Y + L +DPR A +E + + + A A+ AV+N A + T + Sbjct: 333 Y-----EEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVR---TAVINAASGRQTVD 384 Query: 410 AAVQAAQ 416 A++ AQ Sbjct: 385 EALKDAQ 391
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 36.6 bits (85), Expect = 2e-04 Identities = 14/30 (46%), Positives = 21/30 (70%) Query: 462 WTLNSARHHGMEEMTGSLEPGKRADIAVFD 491 +T+N A HG+ GSLE GKRAD+ +++ Sbjct: 409 YTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.037 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 11/80 (13%) Query: 11 QPTPLNNSNLFLSD--TALREAVVREGAGWDGDLLASIGQQLGTAESLELGRLANSNPPE 68 LN L D L+ + AG G A GQQL A + R NP E Sbjct: 189 DADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL-NASIIAQTRFK--NPEE 245 Query: 69 L----LRYDATGA--RLDDV 82 LR ++ G+ RL DV Sbjct: 246 FGKVTLRVNSDGSVVRLKDV 265
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.008 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 709 RVEAVNMDERKIDFTLISSERAPRNVGKTAREKAKKSTSGKPGGRRRQVGKQVNFEPDSA 768 E V + ++ T+ +E+ RE AK++ S + Q E Sbjct: 1036 TTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET 1095 Query: 769 FRKE-KETARPKKEKKAKKPSAKTQKIAAATKAKRAAKKKIAE 810 E KETA +KE+KAK + KTQ++ T ++ + K++ +E Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVT-SQVSPKQEQSE 1137
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 250 bits (640), Expect = 2e-88 Identities = 71/152 (46%), Positives = 104/152 (68%), Gaps = 1/152 (0%) Query: 25 PPGVTVVSPFDVQRYLGTWYEIARFDHPFESGLEKVTIAWHPRDDGGLDVVNKGYNPDRG 84 P V VS F++ YLG WYE+AR DH FE GL +VT + R+DGG+ V+N+GY+ ++G Sbjct: 20 PESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKG 79 Query: 85 MWQKTDGVAYFTGEPSRAALKISFFGPFYGSYNVIALDKE-YRYALVCGPDRDYLWLLAR 143 W++ +G AYF + LK+SFFGPFYGSY V LD+E Y YA V GP+ +YLWLL+R Sbjct: 80 EWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDRENYSYAFVSGPNTEYLWLLSR 139 Query: 144 APTIAPEVRQQMLDIATRQGFDVGKLVWVNQR 175 PT+ + + ++++ +GFD +L++V Q+ Sbjct: 140 TPTVERGILDKFIEMSKERGFDTNRLIYVQQQ 171
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 697 bits (1800), Expect = 0.0 Identities = 298/812 (36%), Positives = 447/812 (55%), Gaps = 58/812 (7%) Query: 3 NGRYLDTRTIKFVANNRASSDNREPALVPCLSLKALAEYGVRIKAFPELA-EDQNGCANF 61 N Y+ TR + F + +VPCL+ LA G+ + + + C Sbjct: 85 NNGYMATRDVTFNTGDSEQG------IVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 62 -SVIPDTKADFDFTAQRLNISIPQAALSTTAQGYIPPDQFDDGINALLVNYQFSGS---N 117 S+I D A D QRLN++IPQA +S A+GYIPP+ +D GINA L+NY FSG+ N Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 118 DMQANDEYYSLNLQSGLNVGPWRIRNLSTWNKNNS-----GAGDWDSAYLYMQRSIRSIN 172 + N Y LNLQSGLN+G WR+R+ +TW+ N+S W +++R I + Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 173 SNLVMGESSSLNGIFDSVPFTGIQLATDTTMLPESMRGYAPIIRGIARTNARVIIKQNGY 232 S L +G+ + IFD + F G QLA+D MLP+S RG+AP+I GIAR A+V IKQNGY Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 233 QVYQTYVAPGAFEITDMYPSGGSGDLYVTVEESDGSKQEFVVPFATLPVMVREDQLEYEI 292 +Y + V PG F I D+Y +G SGDL VT++E+DGS Q F VP++++P++ RE Y I Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 293 TSGKYRPYDGGVDETPFTQATATYGVSSSLTLYGGMQAASRYQALSTGLGYNLGELGAAS 352 T+G+YR + ++ F Q+T +G+ + T+YGG Q A RY+A + G+G N+G LGA S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 353 ADVTQAWSKKKEDEKTSGQSWRVRYGKNIVETGTNVTIAGYRYSTRGFNTLSEVLDSYSN 412 D+TQA S +D + GQS R Y K++ E+GTN+ + GYRYST G+ ++ S N Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 413 DGS------------------YTSRSLRNRTNLTLNQSLGKGLGSLSISGLIEDYWDDKR 454 + + + R + LT+ Q LG+ +L +SG + YW Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 455 TNKSISVGYNGGFRNVNYYLGYSYNRYTWSGDNSGKDAQDDQRITLTVTLPLSNWLPG-- 512 ++ G N F ++N+ L YS + W DQ + L V +P S+WL Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGR-------DQMLALNVNIPFSHWLRSDS 610 Query: 513 ------TYTSYQLTNSNPGSTDQSVSIGGNALENDSLEWSLHQGYSNRE----YYSGDMR 562 SY +++ G + G LE+++L +S+ GY+ +G Sbjct: 611 KSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYAT 670 Query: 563 ATYNGARGSVNAGYSYDNNSQRIDYGANGSILAHADGITLGQDITDAAVLVKAPGLDDVR 622 Y G G+ N GYS+ ++ +++ YG +G +LAHA+G+TLGQ + D VLVKAPG D + Sbjct: 671 LNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAK 730 Query: 623 LANDNTISTDYRGYAIVPYVTPYRRTDITLDSTTLGEDMELPETTKSVVPTRGAIVRASY 682 + N + TD+RGYA++PY T YR + LD+ TL ++++L +VVPTRGAIVRA + Sbjct: 731 VENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEF 790 Query: 683 DGNIGQRAFVHLKTASGQDVPYGAMVLLVGDSKSQPSIVSDAGMVYMSGLQQTGILNVQW 742 +G + + L T + + +P+GAMV IV+D G VY+SG+ G + V+W Sbjct: 791 KARVGIKLLMTL-THNNKPLPFGAMVTSESS--QSSGIVADNGQVYLSGMPLAGKVQVKW 847 Query: 743 GKSAAQQCNASFTLPTREGKASGIRQIETICR 774 G+ C A++ LP + + Q+ CR Sbjct: 848 GEEENAHCVANYQLPPESQQQ-LLTQLSAECR 878
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 118 bits (297), Expect = 3e-31 Identities = 72/430 (16%), Positives = 149/430 (34%), Gaps = 62/430 (14%) Query: 29 PAWLVTCLSLLFLCALICALIFCKFTQRIDVKGEVITLPHSVNVFSPQQGFVVNQYVQIG 88 P + + + A I + + + G++ S + + V V+ G Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 89 DVVKKGQTLYELDVSRNTTTGNVSAAQIEVINEKIAN----------------------- 125 + V+KG L +L + Q ++ ++ Sbjct: 116 ESVRKGDVLLKLTALG--AEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 126 ------SEAIIKKLTHNKNETLIALDAQLKNARNSLNET-------VRMLANTQQGLSKM 172 SE + +LT E Q +L++ + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 173 HENLSSYDKYLKEGLITKDQYNYQHSLYFQQQSAYQSLISQKMQLETQLTQLSSDKVTKA 232 L + L + I K Q + Y + + + SQ Q+E+++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 233 ADFDNQISSQYNQTND----YKNQLVESNAN-GNIIIKATTEGRIESLAV-TKGQMVDKG 286 F N+I + QT D +L ++ +I+A +++ L V T+G +V Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 287 SSLAQIKPIGNIEYYLILWLPNNSIPYVKVGDTINIRYDAFPSDKFGQFPGEIISISSLP 346 +L I P + + + N I ++ VG I+ +AFP ++G G++ +I+ Sbjct: 354 ETLMVIVPEDD-TLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL-- 410 Query: 347 ASRQEMSEYTNVNDGTNQQELAL-YKAIVKIRDKKFNYDGKELSLSNGLKAQAVVFLEER 405 D Q L L + I+ I + + K + LS+G+ A + R Sbjct: 411 -------------DAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457 Query: 406 PLYMWMFTPV 415 + ++ +P+ Sbjct: 458 SVISYLLSPL 467
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.027 Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDSGHIHIRHGDEWVDLV 77 VVL G G GKSTL+ +L H I G + + + Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQI 639
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.002 Identities = 24/115 (20%), Positives = 47/115 (40%), Gaps = 12/115 (10%) Query: 13 LSLTSLAARADIIDDAIGNIQQAINDAYNPGSSRSDDDDRYDDDGRYDDGRYQGS----- 67 L LT+L A AD + +Q + SRS + ++ + D+ +Q Sbjct: 125 LKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 68 -------RQQSRDSQRQYDERQRQLDERRRQLDERQRQLDRDRRQLESDQRRLDD 115 ++Q Q Q +++ LD++R + +++R ++ RLDD Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDD 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.6 bits (134), Expect = 4e-10 Identities = 28/121 (23%), Positives = 58/121 (47%), Gaps = 8/121 (6%) Query: 646 LVLEDEEDVRQTLCEQLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGAD 705 LV +D+ +R L + L + G+ T++ + + A L+++D+++P + D Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDE-NAFD 64 Query: 706 VIHTARRRFPALPVLLISGQDLRPAQNPALPE--VEWLRKPF----TRAQLAQALSAAYA 759 ++ ++ P LPVL++S Q+ A + ++L KPF + +AL+ Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 760 R 760 R Sbjct: 125 R 125
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.7 bits (64), Expect = 0.042 Identities = 26/120 (21%), Positives = 44/120 (36%), Gaps = 12/120 (10%) Query: 155 QLQLVATGGAIASKSQLSFSDPVATVSAKDKKGTIAISQLHISGTTSIQLIPMGCIVGSN 214 Q G + S L S +A + +K GT++ S S G G Sbjct: 367 QWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVS------SSLASALSSFNGIAAGFY 420 Query: 215 NLSFSMGSINASEFNTATKVGSARQSLSLSCEP-----GTNVSMRVAAASASGDNPDNTV 269 +++M + A +T + + ++L G V + + + SGDN NTV Sbjct: 421 QGNWAM-LLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTV 479
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 656 bits (1695), Expect = 0.0 Identities = 286/780 (36%), Positives = 432/780 (55%), Gaps = 60/780 (7%) Query: 2 INTTAYPQL-FEAGETCARL-SAIPGMTFSVSLAQQRIDFTVPQAAMLNRPRDYIPESQW 59 +NT + + A + C L S I T + + QQR++ T+PQA M NR R YIP W Sbjct: 119 LNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELW 178 Query: 60 QQGINAGLLNYSVTGQRNAPRHNGATIDSQFVSLQPGLNLGPWRLRNYSTYSHSDNNS-- 117 GINAGLLNY+ +G R G +++LQ GLN+G WRLR+ +T+S++ ++S Sbjct: 179 DPGINAGLLNYNFSGNSVQNR-IGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSS 237 Query: 118 ----RWESVYSYLARDIHTLRSQLVVGNTYTSSGIFDSLSFTGLQLSSDKEMLPDSLHGF 173 +W+ + ++L RDI LRS+L +G+ YT IFD ++F G QL+SD MLPDS GF Sbjct: 238 GSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGF 297 Query: 174 APTIRGIARTTAEVSVYQNGYSIYKTTVAPGAFEINDLYATGSAGDLYVNIKESDGSEQN 233 AP I GIAR TA+V++ QNGY IY +TV PG F IND+YA G++GDL V IKE+DGS Q Sbjct: 298 APVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQI 357 Query: 234 FVVPFASLAILQREGQLDYALSSGRTRSGSSDDKEYNFIQSSLAYGATSNITLYTGFQQA 293 F VP++S+ +LQREG Y++++G RSG++ ++ F QS+L +G + T+Y G Q A Sbjct: 358 FTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLA 417 Query: 294 EDKYTNLLLGAGFNLGTIGALSFDGSQSWADVKTSDTASSTSKEQGQSYRVRFSKSFLQT 353 + Y G G N+G +GALS D +Q+ + + S+ GQS R ++KS ++ Sbjct: 418 DR-YRAFNFGIGKNMGALGALSVDMTQANSTLP------DDSQHDGQSVRFLYNKSLNES 470 Query: 354 GTSFSVAGYRYSTSGYYSFQDFVD----------------NSSTQRDCCTQSGRTKGRFD 397 GT+ + GYRYSTSGY++F D D + +G+ Sbjct: 471 GTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQ 530 Query: 398 ASLSQTLFGYGSLSLSLVNETYWDSS-RMESVGVGYSGSIGKASYFINYSYNRNVQSTDD 456 +++Q L +L LS ++TYW +S E G + + ++ ++YS +N Sbjct: 531 LTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNA----- 585 Query: 457 SSNNRPSSDTVVSLTLSIPLGETL-----------SANYTLNHGRHNDTTHSVGLNGSAF 505 + D +++L ++IP L SA+Y+++H + T+ G+ G+ Sbjct: 586 ---WQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLL 642 Query: 506 EDRSLNWSVLEGYNTQDKSTSGN---LSVNYQGSKGDVAGGYGYDRYSNHYNYSLRGGMV 562 ED +L++SV GY SG+ ++NY+G G+ GY + Y + GG++ Sbjct: 643 EDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVL 702 Query: 563 AHAGGLTLSRFLGESSALVETPGVSDVTVRGQTNVTTDAAGYAVVPYVRPYHRNSLALDE 622 AHA G+TL + L ++ LV+ PG D V QT V TD GYAV+PY Y N +ALD Sbjct: 703 AHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDT 762 Query: 623 QEIP-GAEVDNVARTVVPTRNAIVKVKYDTRIGYKAMLTLRTRNGVVPFGALVTLDNDHG 681 + ++DN VVPTR AIV+ ++ R+G K ++TL N +PFGA+VT ++ Sbjct: 763 NTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQ- 821 Query: 682 SASRSNIVGDEGQVYLTGLQKKGQLLARWGEKSSEQCTVHYDFSGMALGDDILFYQAECR 741 S IV D GQVYL+G+ G++ +WGE+ + C +Y + + AECR Sbjct: 822 ---SSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.5 bits (76), Expect = 0.001 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGDTR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 756 bits (1952), Expect = 0.0 Identities = 378/396 (95%), Positives = 391/396 (98%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VSVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 V+VEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLVPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDL+PNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKFENGKYDVKDVGVDSAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFK+ENGKYD+KDVGVD+AGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTFKGKPSKPFVGVLSAGINAASPNKE 300 AAFNKGETAMTINGPWAWSNID SKVNYGVT+LPTFKG+PSKPFVGVLSAGINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLMTDQGLEAVNNDKPLGAVALKSFQEKLEKDPRIAATMANAQKGEIMPNIP 360 LAKEFLENYL+TD+GLEAVN DKPLGAVALKS++E+L KDPRIAATM NAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDAALKDAQSRITK 396 QMSAFWYAVRTAVINAASGRQTVD ALKDAQ+RITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 29.6 bits (66), Expect = 0.006 Identities = 8/29 (27%), Positives = 16/29 (55%) Query: 27 AKSLVRERARTGLSLAEVARRAGIAKSTL 55 A L ++ + SL E+A+ AG+ + + Sbjct: 20 ALRLFSQQGVSSTSLGEIAKAAGVTRGAI 48
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 181 bits (462), Expect = 1e-51 Identities = 100/448 (22%), Positives = 172/448 (38%), Gaps = 87/448 (19%) Query: 4 NLRNIAIIAHVDHGKTTLVDKLLQQSGTFD--ARTEAQERVMDSNDLEKERGITILAKNT 61 + NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAHGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMADDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDRVPAPDVDLDGPLQMQISQLDYNNYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I ++ + L ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NGKVGKVLTHLGLERIESDVAEAGDIIAITGLG-ELN--ISDTICDPQNVEALPALSVDE 304 K+ ++ T + E + D A +G+I+ + +LN + DT PQ + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQR----ERIENPL 343 Query: 305 PTVSMFFNVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGEL 364 P + + + D L LR +S G++ Sbjct: 344 PLLQTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKV 394 Query: 365 HLSVLIENMRRE-GFEMAVSRPKVIFRE 391 + V ++ + E+ + P VI+ E Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYME 422 Score = 30.6 bits (69), Expect = 0.019 Identities = 12/75 (16%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPFENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EP+ + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 600 bits (1549), Expect = 0.0 Identities = 203/478 (42%), Positives = 297/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIAWIVDDDSSIRWVLERALTGAGLSCTTFESGNEVLDALTTKTPDVLLSDIRMPGM 60 M + DDD++IR VL +AL+ AG + + + D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVDRAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNAPISSPTADIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDG-MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRSKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTVRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQIAARELGVEAKQLHPETETALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K+ E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLTQDLPSELFETTIPDSPTQMQPDSWATLLGQWADRALRS---- 416 EN R LT + + + + +EL + S + + Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPEMERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L EME L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>SECA#SecA protein signature. Length = 901 Score = 27.9 bits (62), Expect = 0.022 Identities = 12/57 (21%), Positives = 23/57 (40%) Query: 15 KSREELNQEARDRKRQKKHRGHAAGSRANGGDAASAGKKQRQAQDPRVGSKKPIPLG 71 + EE+ + + R+ + + D+A+A Q + +VG P P G Sbjct: 832 RMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCG 888
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 28.8 bits (64), Expect = 0.024 Identities = 11/31 (35%), Positives = 13/31 (41%) Query: 69 NPWLKWDVQGLEGLNKKNWYLLISNHHSWAD 99 N W K +G K +Y S HSW D Sbjct: 214 NAWSKEYARGFAKTGKSIYYSHASMSHSWDD 244
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 2e-14 Identities = 24/116 (20%), Positives = 46/116 (39%), Gaps = 5/116 (4%) Query: 2 TTIALIDDHLIVRSGFAQLLGLEADFQVVAEFGSGREALTGLPGRGVQVCICDISMPDIS 61 TI + DD +R+ Q L + V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALIEQALNAGARGFLSKRCSPDELIAAVRT 114 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.8 bits (85), Expect = 1e-04 Identities = 65/407 (15%), Positives = 130/407 (31%), Gaps = 58/407 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILASNVLTRSDIGLLATLFYITYGLSKFFSG 86 RH + IWL F+ N ++P+I + + T F +T+ + G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSDARYFMGLGLIATGVVNILFGFSSSLWAFALLWALNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L + F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPMVVGAAALHYGWRAGMTIAGCLAILAGLYLC 202 A Y + RG + L + +G + P + G A + W + I I Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITV----- 182 Query: 203 WRLRDRPQAVGLPAVGDWRHDALEIAQQQEGAGMSRKAILTRYVLANPYIWLLSLCYVLV 262 P + L +I G + I+ + Y + VL Sbjct: 183 ------PFLMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANSAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILLSVGGLWLMPFASYVMQAACFFTTGFFVFGPQMLI- 365 GS +F G + + GIL+ G + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT 352 Query: 366 --------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 353 IIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 7e-04 Identities = 27/168 (16%), Positives = 62/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--- 89 Query: 109 MLGFSASMGAGSTSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 F + +G S F ++ + F Q G + + + ++ P+ RG G Sbjct: 90 --CFGSVIGFVGHSFFSLLIM---ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 27/151 (17%), Positives = 53/151 (35%), Gaps = 3/151 (1%) Query: 65 AFVAMFSSLFITTVIGKTDRRYVVILFSLLLTLSCLLVSFADSFTLLLLGRACLGLALGG 124 A + + + + + RR V+++ + +++ A +L +GR G+ G Sbjct: 53 ALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GA 111 Query: 125 FWAMSASLTMRLVPMRVVPKALSIIFGAVSIALVIAAPLGSFLGGLIGWRNVFNGAAVMG 184 A++ + + + + +V LG +GG F AA + Sbjct: 112 TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALN 170 Query: 185 VLCTLWVLKALP-SLPGESASQQQNMFGLLK 214 L L LP S GE ++ L Sbjct: 171 GLNFLTGCFLLPESHKGERRPLRREALNPLA 201
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 118 bits (296), Expect = 6e-34 Identities = 43/124 (34%), Positives = 65/124 (52%), Gaps = 11/124 (8%) Query: 108 LNMPNNVTFDSNSANLKPAGANTLTGVAMVLKEYEKT--AVNVVGYTDSTGSKDLNMRLS 165 + ++V F+ N A LKP G L + L + +V V+GYTD GS N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVAANRIRTTGMGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A++I GMG +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SPLQ 220 ++ Sbjct: 335 KGIK 338
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 1e-04 Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%) Query: 76 VAPGATRQGIGRALLDEIKQ-----HYAWLSLEVYQKNESAVSFYHAQGFRI 122 VA ++G+G ALL + + H+ L LE N SA FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 4e-06 Identities = 48/276 (17%), Positives = 92/276 (33%), Gaps = 33/276 (11%) Query: 44 PVSQVAFSFGLLSLGLALS----SSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSSSL 99 + V +G+L AL + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFSIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDSHLLATVGLEKTFVIWGAIVLVMIVFGATLMKDAPNHPAATAANGVVENDFTLAESM 212 L+ F A+ + + G L+ + + N Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPE-SHKGERRPLRREALNPLASFRWA 206 Query: 213 R--KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQGMVHLDVATAANAVTVISIAN-L 265 R ++AV F+ + L+VI + H D T ++ I + L Sbjct: 207 RGMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSL 261 Query: 266 SGRLVLGILSDKISRIRVITIGQVVSLVGMAALLFA 301 + ++ G ++ ++ R + +G + G L FA Sbjct: 262 AQAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 34.0 bits (78), Expect = 9e-04 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Query: 270 VLGILSDKISRIRVITIGQVVSLVGMAALLFAPLNALTFFAAIACVAFNFGGTITVFPSL 329 VLG LSD+ R V+ + + V A + AP + + I VA G T V + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRI--VAGITGATGAVAGAY 119 Query: 330 VSEFFGLNNLAKNYGVIYLGFGIGSICGSLIASLFGGFYVTFCVIFALLILSLALSTTI 388 +++ + A+++G + FG G + G ++ L GGF A + L T Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.049 Identities = 23/137 (16%), Positives = 43/137 (31%), Gaps = 23/137 (16%) Query: 5 RTMTQQKLSFWLALYIGWFMNVAVFFRRFDGYAQEFTFWKGLSGVVELVATVFVTFFLLR 64 T Q +W IGW + F G+A + K S + + ++ Sbjct: 3 STHRQANKYYWYCQGIGWGVYTLTGF----GFASLYGSPKLHSMIFNIAISLMGLVLTHA 58 Query: 65 LLSLFGRRIWRILATLIVLFSAAASYYMTFLNVVIGYGIIASVMTTDIDLSKEVIGWHLI 124 S R+ W L ++ + + G++ V T I W L+ Sbjct: 59 YRSFIKRQGWLKLNMGQIILRVLPA--------CVVIGMVWFVANTSI--------WRLL 102 Query: 125 LWLVAVSAPPLLFIWSN 141 ++ + P+ F Sbjct: 103 AFI---NTKPVAFTLPL 116
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 38.2 bits (88), Expect = 6e-05 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 17/175 (9%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPDQPPKTWQDLAAYTAKLKAAGMKCGYASGWQ 193 G L++ P L YNKD L P+ PPKTW+++ A +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKD------LLPN-PPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQIENFSAWHGLPVATKNNGFDGTDAVLEF--NKPEQVKHIALLEEMNKKGDFSYFGR 251 + +A G +N +D D ++ K + L++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAITTASSGSLADIRQYAKFNYGVGMMPYDADVKGAPQNAIIG 306 + F G+ A+T + ++I +K NYGV ++P KG P +G Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNIDT-SKVNYGVTVLP---TFKGQPSKPFVG 286
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.037 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTSGDI 61 +V+ G G GKSTL+ + GL+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>PF04619#Dr-family adhesin Length = 160 Score = 28.4 bits (63), Expect = 0.017 Identities = 14/60 (23%), Positives = 23/60 (38%), Gaps = 4/60 (6%) Query: 29 VGARYGHTMIEFDAKLSKDGQIFLLHDDNLERTSNGWGVAGELAW----DDLLKVDAGSW 84 +G ++ D + G+ FL+ D+N ++ AW K D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 33.2 bits (75), Expect = 0.003 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 13/80 (16%) Query: 276 RTPVSGEYRGYEVYSMPPPSSGGIHIVQILNILENFDMQKYGF-GSADAMQVMAEAEKHA 334 R P+ GE R + SMPPP G H +I N+ F Q G+ G A +++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNL--KFFKQFDGYVGGQTAWGILSELEKGR 133 Query: 335 YADRSEYLGDPDFVNVPWQA 354 Y P F WQ+ Sbjct: 134 Y---------PTFSYQDWQS 144
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 1e-05 Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 13/63 (20%) Query: 80 MAVAAGHQGCGIGSALMREMID------LCDNWLRVERIELTVFADNAPAIAVYKKYGFE 133 +AVA ++ G+G+AL+ + I+ C L + I N A Y K+ F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDI-------NISACHFYAKHHFI 147 Query: 134 IEG 136 I Sbjct: 148 IGA 150
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.8 bits (74), Expect = 5e-04 Identities = 28/118 (23%), Positives = 43/118 (36%), Gaps = 16/118 (13%) Query: 37 LLVSRTARLQRDFLATLHTTADAQLLASLKQREQAMREAWQQHQRQRQQYQRRSAIAAWQ 96 L + LQ A + A+ K REQA EA +++ + Q R A Sbjct: 192 LFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEA-----KRKAEEQARQQAAIRA 246 Query: 97 PRLQVLAAD----LPAQAWLTRLEYQGVLLTLDGLALNLQALTSVEAALTRVAGFAPA 150 + A+ A +G++ G A QA++ A L RV AP+ Sbjct: 247 ANTYAMPANGSVVATAAG-------RGLIQVAQGAASLAQAISDAIAVLGRVLASAPS 297
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 226 bits (578), Expect = 3e-70 Identities = 77/282 (27%), Positives = 122/282 (43%), Gaps = 17/282 (6%) Query: 138 GGKLLSARGHLMADKRTNRLLIRDDARHLPALKAWAQEMDLPVGQVELAAHIVSMSETSL 197 SA+ + AD N +++RD +P + +D P ++E+A IV ++ L Sbjct: 237 AATRASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQL 296 Query: 198 RELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGKINGRLLEL---ELSALE 254 ELGV WR+ I T ++ G ++ R L+ ++ LE Sbjct: 297 TELGVDWRVGIRTGNNHQVVIKTTGDQSNIAS----NGALGSLVDARGLDYLLARVNLLE 352 Query: 255 RKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFKEAVLG--MEVTPTV 312 + ++++ P LL A I SE Y +G+ A E K G + +TP V Sbjct: 353 NEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA---ELKGITYGTMLRMTPRV 408 Query: 313 LQQG---RVRLKLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETLALGGIFSQK 369 L QG + L L I + I + ++T+ V G++L +GGI+ + Sbjct: 409 LTQGDKSEISLNLHIEDGNQKPNS-SGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDE 467 Query: 370 NKTARDSVPLLGDIPVLGRLFRRDGKDNERRELVVFITPRIL 411 A VPLLGDIP +G LFRR + R + I PRI+ Sbjct: 468 LSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRII 509
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.6 bits (69), Expect = 0.002 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 20 FYDSDQEIEKRTGADVGWVFDVEGEEGFRD----------REEKIINELTEKQGIVLATG 69 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 70 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 100 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 6e-04 Identities = 38/211 (18%), Positives = 63/211 (29%), Gaps = 18/211 (8%) Query: 125 SSSQQTASGEKSINLSDDQSASMPAAGQDQTAAANSTSQQDVTVPPIAANPTQGQAAAAP 184 S + A + +T A NS + Q A Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTV-------EKNEQDATET 1061 Query: 185 QGQQRIEVQGDLNN--ALTQQ----QGQLDGAVANSTLPTEPATVAPIRNGANGTAAPRQ 238 Q R + +N A TQ Q + +T E ATV T ++ Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 239 ATERQTAATPRPAERKHTVIEAKPQSKPQAVAKTPVESKPVQPKHVESTATTAPAKTSVS 298 + + +P+ + + +PQ++P V K Q + + T PAK + S Sbjct: 1122 VPKVTSQVSPKQEQSE----TVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Query: 299 ESKPVATAQSKPTTTTAAPAATAAAAAPAAK 329 + T +S T + PA Sbjct: 1178 NVEQPVT-ESTTVNTGNSVVENPENTTPATT 1207
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 179/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W +VNIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVGQIKTRLGANPVPLQLAIGAEEGFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMQDLADEWHQNLIESAAEASEELMEKYLGGEELTEEEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KKALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 ++ R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKKA---EYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLRGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDDAPNNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 4e-18 Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 13/154 (8%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGSARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G+ R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ 160 G+P I F+NK D + L V +++E LS Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSA 150
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 36.8 bits (85), Expect = 9e-06 Identities = 18/103 (17%), Positives = 42/103 (40%), Gaps = 10/103 (9%) Query: 44 EYHESIDEMKHADKYIERILFLEGIPN--LQDLGKL------GIGEDVEEMLRSDLRLEL 95 E ++ E D ER+L + G P +++ + G EM+++ + Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 EGAQNLREAIAYADSVHDYVSRDMMIEILADEEGHIDWLETEL 138 + + + I A+ D + D+ + ++ + E + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 122 bits (308), Expect = 5e-37 Identities = 67/150 (44%), Positives = 85/150 (56%), Gaps = 7/150 (4%) Query: 2 LAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAIT 61 L LL L VAL DL LLPD+ T PLLW GLLF L L DAV GA+ Sbjct: 132 WGTLAALLLTWVL-VALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMA 190 Query: 62 GYLSLAAIYWLYRGIRGYEGLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGAG 121 GYL L ++YW ++ + G EG+GYGD K LAALGAW GW+ LP ++L++SL+ Sbjct: 191 GYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFM---GI 247 Query: 122 LYASCGRKSKWGRSNPLPFGPFLAAAGFWC 151 +S P+PFGP+LA AG+ Sbjct: 248 GLILLRNHH---QSKPIPFGPYLAIAGWIA 274
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.005 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 3/65 (4%) Query: 1 MKKYLIVALLASLLAGCAHDSPCV---PVYDSQGRLVHTNTCMKGTTEDNWETAGAIAGG 57 MKK L A LA L+ GCA + V P + + + + G + A I GG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 58 AAAVA 62 A V Sbjct: 66 AENVV 70
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1372 bits (3554), Expect = 0.0 Identities = 892/1032 (86%), Positives = 958/1032 (92%), Gaps = 1/1032 (0%) Query: 1 MSKFFIHRPVFAWVLAIIMMIAGGLAILQLPIAQYPTIAPPAVAISATYPGADAQTVQDT 60 M+ FFI RP+FAWVLAII+M+AG LAILQLP+AQYPTIAPPAV++SA YPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFKSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTF+SGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSFLLVAGFISDNPTTTQDDISDYVASNVKDPISRLNGVGDVQLFGA 180 EVQQQGISVEKSSSS+L+VAGF+SDNP TTQDDISDYVASNVKD +SRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRVWLDGNLLNKYNLTPVDVINALQVQNDQIAAGQLGGTPALKGQQLNASIIAQTRL 240 QYAMR+WLD +LLNKY LTPVDVIN L+VQNDQIAAGQLGGTPAL GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KDPQEFGKVTLRVNADGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL 300 K+P+EFGKVTLRVN+DGSVV LKDVAR+ELGGENYNV+ARINGKPA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTATAIKAKLAELQPYFPQGMKVVYPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLFLQ 360 DTA AIKAKLAELQP+FPQGMKV+YPYDTTPFV++SIHEVVKTLFEAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAVLSMFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFA+L+ FGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 VEEKLSPKEATEKSMSQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 +E+KL PKEATEKSMSQIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALVLTPALCATLLKPASAEHHE-KKGFFGWFNARFDQSVNHYTNSVSGILRGTGRY 539 SVLVAL+LTPALCATLLKP SAEHHE K GFFGWFN FD SVNHYTNSV IL TGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 LVIYLLIVVGMAVLFMRLHTSFLPDEDQGVFLTMIQLPSGATQERTQKVLDTVTDYYLHN 599 L+IY LIV GM VLF+RL +SFLP+EDQGVFLTMIQLP+GATQERTQKVLD VTDYYL N Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 600 EKANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEARSGDENSVESIIKRATVAFSQIKDA 659 EKANVESVFTVNGFSFSGQ QN+GMAFVSLKPWE R+GDENS E++I RA + +I+D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 660 MVFPFNMPAIIELGTATGFDFELIDQGGLGHTALTQARNQLLGMVKQHPDQLVRVRPNGL 719 V PFNMPAI+ELGTATGFDFELIDQ GLGH ALTQARNQLLGM QHP LV VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 EDTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAHFRM 779 EDT QFKL+VDQEKAQALGVSLSDIN+TIS ALGG YVNDFIDRGRVKK+YVQADA FRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 780 LPSDINNMYVRSANGEMVPFSAFVTSRWIYGSPRLERYNGLPSMEILGEASPGKSTGEAM 839 LP D++ +YVRSANGEMVPFSAF TS W+YGSPRLERYNGLPSMEI GEA+PG S+G+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 840 ALMETLASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV 899 ALME LASKLP+GIGYDWTGMSYQERLSGNQAPAL AIS +VVFLCLAALYESWSIP SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 900 MLVVPLGVIGALLAATLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGII 959 MLVVPLG++G LLAATL NDVYF VGLLTTIGLSAKNAILIVEFAKDLMEKEGKG++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 960 EATLEASRMRLRPILMTSLAFILGVMPLVISHGAGSGAQNAVGTGVMGGMLTATLLAIFF 1019 EATL A RMRLRPILMTSLAFILGV+PL IS+GAGSGAQNAVG GVMGGM++ATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1020 VPVFFVVVRRRF 1031 VPVFFVV+RR F Sbjct: 1021 VPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 1e-04 Identities = 34/211 (16%), Positives = 67/211 (31%), Gaps = 30/211 (14%) Query: 97 ATYQAAWNSAKGDEAKAEAAAAIAHLTVKRYVPLLGTKYISQQEYDQAVATA-RQADADV 155 K + E+ A + Q + + RQ ++ Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 156 IATKAAVETARINLAYTKVTSPISGRIGKSSV-TEGALVTNGQSDALATVQQLDPIYVDV 214 + + + +P+S ++ + V TEG +VT ++ + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET-LMVIVPEDDTLEVTA 370 Query: 215 TESSNDFMRLKQESLQRGGDTKSVELVMENGQAYP-LKGSLQ--FSDVTVDESTG----- 266 + D + G +++ Y L G ++ D D+ G Sbjct: 371 LVQNKDIGFINV------GQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNV 424 Query: 267 --SITLRAIFPNPQHV-LLPGMFVRARIDEG 294 SI + +++ L GM V A I G Sbjct: 425 IISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 35.2 bits (81), Expect = 3e-04 Identities = 23/127 (18%), Positives = 41/127 (32%), Gaps = 15/127 (11%) Query: 46 APLSVTTELPGR-TSAFRVAEVRPQVSGIILKRNFV-EGSDVEAGQSLYQIDPATYQAAW 103 + + G+ T + R E++P + I+ K V EG V G L ++ +A Sbjct: 78 GQVEIVATANGKLTHSGRSKEIKPIENSIV-KEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 104 NSAKGDEAKAEAAAAIAHLTVKRYVPLLGTKYISQQEYDQAVATARQADADVIATKAAVE 163 D K +++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 164 TARINLA 170 +L Sbjct: 185 LRLTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 118 bits (297), Expect = 2e-35 Identities = 77/201 (38%), Positives = 124/201 (61%), Gaps = 3/201 (1%) Query: 1 MARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFN 60 MARKTK+EAQ TRQ +++ A++ F+ +GV++T+L +IA AAGVTRGA+YWHF K++LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-QQQPPLRDLIQPSQAIEYEHEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEF 119 E+W + + +L QA ++ +PL+ LRE I L R+R LM+I++ +CEF Sbjct: 61 EIWELSESNIGELELEYQA-KFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 SSDMLSEYEIRQRIGF-NYSLIGGILQCCVRNNILPAETNIEMILIVLHSAFSGLIKNWL 178 +M + ++ + +Y I L+ C+ +LPA+ I++ SGL++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 LDPQRFDLYQQAPALVDNIMA 199 PQ FDL ++A V ++ Sbjct: 180 FAPQSFDLKKEARDYVAILLE 200
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.7 bits (248), Expect = 3e-27 Identities = 72/256 (28%), Positives = 122/256 (47%), Gaps = 20/256 (7%) Query: 5 LNGKRIVVTGAARGLGYHFAEACAAQGATVVMCDILQGELAESAHRLQRKGYQVESHAID 64 + GK +TGAA+G+G A A+QGA + D +L + L+ + E+ D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 LASQASIEQVFSAIGAQ-GSIDGLVNNAAMATGVGGKNMIDYDPDLWDRVMTVNVKGTWL 123 + A+I+++ + I + G ID LVN A + ++ D + W+ +VN G + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE---WEATFSVNSTGVFN 122 Query: 124 VTRAAVPLL--REGAAIVNVASDTALWGAPR--LMAYVASKGAVIAMTRSMARELGEKRI 179 +R+ + R +IV V S+ A G PR + AY +SK A + T+ + EL E I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 180 RINAIAPGLTRVE----------ATEYVPAERHQLYENGRALSGAQQPEDVTGSVVWLLS 229 R N ++PG T + E V + ++ G L +P D+ +V++L+S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 230 DLSRFITGQLIPVNGG 245 + IT + V+GG Sbjct: 241 GQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (276), Expect = 2e-31 Identities = 72/257 (28%), Positives = 132/257 (51%), Gaps = 11/257 (4%) Query: 3 LDAFSLQGKVAVVSGCDTGLGQGMALGLAEAGCDIVGI--NIVEPVETIERVTALGRRFL 60 ++A ++GK+A ++G G+G+ +A LA G I + N + + + + A R Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 61 SLTADLRQIDGIPQLLERAVAEFGHIDILVNNAGLIRREDALAFSEKDWDDVMNLNIKSV 120 + AD+R I ++ R E G IDILVN AG++R + S+++W+ ++N V Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 121 FFMSQAAAKHFIAQGSGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLLANEWAKHN 180 F S++ +K+ + + G I+ + S + + +Y +SK+A + T+ L E A++N Sbjct: 121 FNASRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 181 INVNAIAPGYMATNNTQQLRADEQRSSEILD--------RIPAGRWGLPADLMGPVVFLA 232 I N ++PG T+ L ADE + +++ IP + P+D+ V+FL Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 233 SSASDYINGYTVAVDGG 249 S + +I + + VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 55.3 bits (133), Expect = 3e-10 Identities = 66/371 (17%), Positives = 131/371 (35%), Gaps = 34/371 (9%) Query: 43 LDIGVISGALPFITDHFTLSSQLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAV 102 L+ V++ +LP I + F WV ++ ML +IG G LS +LG K L+ G + Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 103 LFVAGSIGSAFAAS-VEVLLVARVVLGVAVGIASYTAPLYLSEMASENVRGKMISMYQLM 161 + GS+ S +L++AR + G + ++ + RGK + + Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 162 VTLGIVLAFLSDTAFSYSGNWRAMLGVLALPAVILIILVVFLPNSPRWLAEKGRHIEAEE 221 V +G + ++ +W L L +I II V FL + H + + Sbjct: 148 VAMGEGVGPAIGGMIAHYIHW----SYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKG 203 Query: 222 VLRMLRDTSEKARDELNEIRESLKLKQGGWALFKV----------------NRNVRRAVF 265 ++ M + L + + +F N V Sbjct: 204 IILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL 263 Query: 266 LGMLLQAMQQFTGMNIIMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDK 325 G + G ++ Y + + +T E + ++ + +I VD+ Sbjct: 264 CGGI--IFGTVAGFVSMVPYMMK--DVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDR 319 Query: 326 AGRKPALKIGFSVMALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVV 385 G L IG + +++ L + T SW + + + G + + + Sbjct: 320 RGPLYVLNIGVTFLSVSFLTASF----LLETT-----SWFMTIIIVFVLGGLSFTKTVIS 370 Query: 386 WILCSEIQPLK 396 I+ S ++ + Sbjct: 371 TIVSSSLKQQE 381
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.036 Identities = 31/142 (21%), Positives = 48/142 (33%), Gaps = 8/142 (5%) Query: 43 AGDTGIIYAVLSVSALFAQVCYGFIQDKLGLRKHLLWYITALLILSGPAYLLFGHLLKIN 102 GI+ A+ ++ G + D+ G R LL L + Y + + Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLL----VSLAGAAVDYAIMATAPFLW 97 Query: 103 VL-LGSIFGGIYIGLTFNGGIGVLESYTERVARQSQFEFGRARMWGSLGWAVATFFAGLL 161 VL +G I GI G T + T+ R F F A G GL+ Sbjct: 98 VLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACF--GFGMVAGPVLGGLM 154 Query: 162 FNINPQLNFLVASCSGLVFFIL 183 +P F A+ + F+ Sbjct: 155 GGFSPHAPFFAAAALNGLNFLT 176
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 29.7 bits (66), Expect = 0.024 Identities = 72/298 (24%), Positives = 118/298 (39%), Gaps = 41/298 (13%) Query: 128 NGKLNGIPISVTARVFYFNDEAWKKAGIPFPKTWDELMAAGKTFESKLGKQYYPVVLEHQ 187 NGKL PI+V A +N + PKTW+E+ A K ++K GK L+ Sbjct: 126 NGKLIAYPIAVEALSLIYNKDLLPNP----PKTWEEIPALDKELKAK-GKSALMFNLQEP 180 Query: 188 ----DVLALLNSYMVQKYNQPAIDEKGRKFSYSKAQWADFFGMYKKLIDSHVMPDTRYYA 243 ++A Y KY D K + A+ F + + + H+ DT Y Sbjct: 181 YFTWPLIAADGGYAF-KYENGKYDIKDVGVDNAGAKAGLTF-LVDLIKNKHMNADTDYSI 238 Query: 244 SFGKSNMYEMKPWIQGEWGGTYMWNSTINKYSDNLKPPAKLVLGEYPMLP--GATDAGLF 301 + N E I G W + + S +N Y + P K P P G AG Sbjct: 239 AEAAFNKGETAMTINGPWAWSNIDTSKVN-YGVTVLPTFK----GQPSKPFVGVLSAG-- 291 Query: 302 FKPAQMLSIGKSTKNPQAAAKVINFLLNSKEGVDILGLERGVPLSKAAVTYLTEDGVIKA 361 I ++ N + A + + L + EG++ + ++ PL A+ E+ A Sbjct: 292 --------INAASPNKELAKEFLENYLLTDEGLEAVNKDK--PLGAVALKSYEEE---LA 338 Query: 362 DDPAVSGLKLAQSLPTALPVSPYFDDPQIVA---QFGTTLQYIDYGKKSVEEAAEDFQ 416 DP ++A ++ A + PQ+ A T + G+++V+EA +D Q Sbjct: 339 KDP-----RIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQ 391
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 35.5 bits (81), Expect = 3e-04 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 10/95 (10%) Query: 60 EVRIGDKIVNNLAPKSRGIAM-VFQNYALYPHMTVRENLAFGLKLSKLPKAQIDRQVEEA 118 +V +G ++ N A + G+A VF A E LA L++ QI + ++++ Sbjct: 504 KVALGMEVTNTAAQSAGGVAEGVFIKNA-------SEALA-DFMLARFAMDQIQQWLKQS 555 Query: 119 AKIL-ELEELLDRLPRQLSGGQAQRVAVGRAIVKK 152 +I E +++ L + +S Q R I+++ Sbjct: 556 VEIFGENQKVTAELQKAMSSAVQQNADASRFILRQ 590
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.028 Identities = 11/25 (44%), Positives = 14/25 (56%) Query: 47 IVGESGSGKSTVGRALLQLHPKKAR 71 I GESG+GK V RAL ++ Sbjct: 165 ITGESGTGKELVARALHDYGKRRNG 189
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.008 Identities = 19/93 (20%), Positives = 28/93 (30%), Gaps = 35/93 (37%) Query: 36 LVGESGSGKTTVLKCLAGLFTHWQGELTI---------------------------DAQP 68 L G G GK+T++ L GL I DA+ Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFRRADAEA 660 Query: 69 LGHEISRERCRQVQMVFQDPYGSL---HPRHTI 98 + S + R ++ YG HPR + Sbjct: 661 VKAFFSSRKDR-----YRGAYGRYVQDHPRQVV 688
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 4e-18 Identities = 31/148 (20%), Positives = 67/148 (45%), Gaps = 3/148 (2%) Query: 11 PRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGL 70 IL+ +D+ + +L L AGY + ++ + ++ L++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTIL--RR 127 L I+ D+PV++++A+ + + E GA DY+ KP+ E++ + L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 128 CKPQRDLQALDAQSPLIVDEGRFQASWR 155 +P + PL+ Q +R Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYR 151
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 36.3 bits (84), Expect = 2e-04 Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 21/93 (22%) Query: 198 LATLLAA-------------LATFPLARGLLAPVKRLVEGTHKLAA------GDFST--R 236 LATL+AA + P L+A V+ V H LA G F Sbjct: 77 LATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKCFPGSFERLYC 136 Query: 237 VTVTGGDELGRLAQDFNQLASTLERNQQMRRDL 269 V G+ G L N+LA E+ QQMR + Sbjct: 137 AMVAAGETSGHLDAVLNRLADYTEQRQQMRSRI 169
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (311), Expect = 5e-33 Identities = 93/435 (21%), Positives = 186/435 (42%), Gaps = 17/435 (3%) Query: 20 FMQSLDTTIVNTALPSMAKSLGESPLHMHMIIVSYVLTVAVMLPASGWLADRVGVRNIFF 79 F L+ ++N +LP +A + P + + +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTAGSLFCAQA-STLDQLVMARVLQGVGGAMMVPVGRLTVMKIVPRDQYMAAMTF 138 I++ GS+ S L+MAR +QG G A + + V + +P++ A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGVLVEYASWHWIFLINIP-VGIVGAIATLCLMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP + I+ + L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAAGMATLTLALDGQKGLGISPAWLAGLVAVGLCALLLYLWHARGNARALFSLNL 257 G +L++ G+ L + ++ + V + + L+++ H R L Sbjct: 202 KGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRNRTFSLGLGGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 +N F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVASTLGLAAVSLLFMFSALAGWYYVLPLVLFLQGMINASRFSSMNT 376 +V+R G VL L+ L F +++ +++F+ G ++ ++ + ++T Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK-TVIST 371 Query: 377 LTLKDLPDDLASSGNSLLSMVMQLSMSIGVTIAGLLLGLYGQQHMSLDAASTHQVFLYT- 435 + L A +G SLL+ LS G+ I G LL + L +LY+ Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSN 431 Query: 436 -YLSMAAIIALPALI 449 L + II + L+ Sbjct: 432 LLLLFSGIIVISWLV 446
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 890 bits (2302), Expect = 0.0 Identities = 281/1035 (27%), Positives = 502/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILISLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ ++++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVNEMTSSS-SLGSTRIILEFNFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAQTIAQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+++++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVDLNPQALFNQGVSLDAVRTAISDANVRKPQG------ALEDSAHRWQVQTNDELK 236 A+R+ L+ L ++ V + N + G AL + K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAADYQPLIVHY-QNGAAVRLGDVATVSDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 ++ + + +G+ VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRARLPELQQTIPAAIDLQIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRS 355 T +I+A+L ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHL- 414 RATLIP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGSREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LAVSLTLTPMMCGWLLKSGKPHQPTRNRGFG----RLLVAVQGGYGKSLKWVLKHSRLTG 530 + V+L LTP +C LLK GF Y S+ +L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 LVVLGTIALSVWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 L+ +A V L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 R-EDPAVDNVTGFT-GGSRVNSGMMFITLKPRDQRH---ETAQQVIDRLRKKLANEPGAN 641 + +V V GF+ G N+GM F++LKP ++R+ +A+ VI R + +L Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLSALREWEPKIRKALA-----VLPELADVNSD 696 + + I G + ++ L D + + R L L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMDLVYDRDTMSRLGISVQDANNLLNNAFGQRQISTIYQPLNQYKVVMEVDPAY 756 ++ A+ L D++ LG+S+ D N ++ A G ++ K+ ++ D + Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDVSALDKMFVINSDGKPIPLAYFAKWQPANAPLSVNHQGLSAASTISFNLPTGRSLSE 816 +DK++V +++G+ +P + F + + I G S + Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASEAIDRAMTQLGVPSSVRGSFAGTAQVFQQTMNAQVILILAAIATVYIVLGVLYESYVH 876 A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALEIFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGN 936 P++++ +P VG LLA +F+ + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPEEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 899 bits (2324), Expect = 0.0 Identities = 294/1036 (28%), Positives = 508/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRFLPVSALPEVDYPTIQVVTLYPGASPDVVTSAI 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA V + Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ +TL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSSAIPMTQVE--DMVETRVAQKISQVSGVGLVTLAGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITSANVNSAKGSLDGP------ARAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEDYRRLII-AYQNGAPIRLGDVASVEQGAENSWLGAWANQQRAIVMNVQRQPGANI 302 ++ E++ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 IDTADSIRQMLPQLTESLPKSVKVQVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFL 362 +DTA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNVPATIIPGVAVPLSLVGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F++T+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SHESLRKQNRFSRASERFFERVIAIYGRWLSRVLNHPWL 538 +S +V+L LTP +CA +L S E + F F+ + Y + ++L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLGVALSTLALSIILWVFIPKGFFPIQDNGIIQGTLQAPQSVSFASMAERQRQVASIILK 598 L + +A ++L++ +P F P +D G+ +Q P + + QV LK Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VESLTSFVGVDGTNPALNSARLQINLKPLDERDDR---VQTVISRLQQAVDGVPG 653 + VES+ + G + A N+ ++LKP +ER+ + VI R + + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 654 VALYLQPTQDLTIDTTVSRTQYQFTLQ---ANSLEALSTWVPPLLSRLQAQP-QLADVSS 709 ++ P I + T + F L +AL+ LL P L V Sbjct: 660 G--FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLAAYIKVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEQDTE 769 + + ++VD++ A LG+S++D++ + A G ++ + ++ ++ D + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 ATPGLAALENIRLTSSDGGIVPLTAIATVEQRFTPLSVNHLDQFPVTTISFNVPDNYSLG 829 ++ + + S++G +VP +A T + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 EAVEAILAAEQSLDFPTDIRTQFQGSSLAFQSALGSTVWLVVAAVVAMYIVLGVLYESFI 889 +A+ + L P I + G S + + LV + V +++ L LYES+ Sbjct: 838 DAMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALWLAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA L + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMPPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLMLSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 6e-07 Identities = 26/139 (18%), Positives = 52/139 (37%), Gaps = 16/139 (11%) Query: 55 GAALAPVQAATATEEAVPRYLTGLGTVTAA-NTVTVRSRVDGQLLSLHFQEGQQVKAGDL 113 +A + + E V T G +T + + ++ + + + +EG+ V+ GD+ Sbjct: 67 FLVIAFILSVLGQVEIV---ATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDV 123 Query: 114 LAQIDPSQFKVALAQAQGQLAKDQATLANARRDLARYQQLVKTNLVSRQELDTQQSLVVE 173 L ++ A+ K Q++L AR + RYQ L ++ EL+ L + Sbjct: 124 LLKLTAL-------GAEADTLKTQSSLLQARLEQTRYQILSRS-----IELNKLPELKLP 171 Query: 174 SAGTVKADEAAVASAQLQL 192 + L Sbjct: 172 DEPYFQNVSEEEVLRLTSL 190 Score = 36.3 bits (84), Expect = 2e-04 Identities = 26/170 (15%), Positives = 63/170 (37%), Gaps = 17/170 (10%) Query: 125 ALAQAQGQLAKDQATLANARRDLARYQQLVKTNLVSRQELDTQQSLVVESAGTVKADEAA 184 +A +L ++ L ++ ++ + ++ +++ + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEY------QLVTQLFKNEILDKLRQTTDNIGL 313 Query: 185 V----ASAQLQLDWTRITAPIDGRV-GLKQVDIGNQISSGDTTGIVVLTQTHPIDVVFTL 239 + A + + + I AP+ +V LK G +++ +T ++V ++V + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPED-DTLEVTALV 372 Query: 240 PESSIATVVQAQKAGKALSVEAWDRTNKQKISVGE--LLSLDNQIDATTG 287 I + Q A + VEA+ T + G+ ++LD D G Sbjct: 373 QNKDIGFINVGQNA--IIKVEAFPYTRYGYLV-GKVKNINLDAIEDQRLG 419
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 1e-14 Identities = 33/141 (23%), Positives = 62/141 (43%), Gaps = 6/141 (4%) Query: 4 RLAIIEDNADLLDELLAWLGYRGFEVWGTRSAEAFWRQLHSHPVDIVLVDIGLPGEDGFS 63 + + +D+A + L L G++V T +A WR + + D+V+ D+ +P E+ F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 VLNYLHELGHY-GLVVVSARGQQQDKLQALSLGADAYLIKPVNFAH-LAETLTALGARLR 121 +L + + ++V+SA+ ++A GA YL KP + + AL R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 QDRPAAPPAQ----AIGTPPA 138 + +Q +G A Sbjct: 125 RPSKLEDDSQDGMPLVGRSAA 145
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 46.3 bits (110), Expect = 1e-07 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 20/129 (15%) Query: 165 AMMLH-IKLQAESQLPEQIDQAVIGRPINFQGLGGDEANAQAQGILERAAHRAGFRDVVF 223 M+ H IK + + ++ P+ + E A + +A AG R+V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV---ERRA-----IRESAQGAGAREVFL 140 Query: 224 QFEPVAAGLDFEATLSEEKRVLVVDIGGGTTDCSLLLMGPQWRERADRQQSLLGHSGCRI 283 EP+AA + +SE +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 284 GGNDLDIAL 292 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 35.1 bits (81), Expect = 4e-04 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 22/121 (18%) Query: 365 RLSYRLV---RSAEESKIALSSA--ASVETALPFIQDDLATA------IAQQGLEAALDQ 413 R +Y + +AE K + SA + +LA + + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 414 PLTRIMEQVRLALDSSQTTPDV--------IYLTGGSARSPLIKKALAAQLPGIPLAGGD 465 PLT I+ V +AL+ Q P++ + LTGG A + + L + GIP+ + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 466 D 466 D Sbjct: 320 D 320
>INTIMIN#Intimin signature. Length = 939 Score = 228 bits (583), Expect = 1e-68 Identities = 116/408 (28%), Positives = 198/408 (48%), Gaps = 15/408 (3%) Query: 31 PDMGIAPQVDDDARHFAEVAKKFGEASMSDNGLTAGEQAQLFAISKIGNEVSHQLESWLS 90 PD+ + DD A ++A + + L G+ A+ A+ GN+ S QL++WL Sbjct: 150 PDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLN-GDYAKDTALGIAGNQASSQLQAWLQ 208 Query: 91 PWGNANVDLLVDKEGKFTGSKGSWFVPLQDNDRYLTWNQYSVTRREHDLVGNIGLGQRWR 150 +G A V+L F GS + +P D+++ L + Q + N+G GQR+ Sbjct: 209 HYGTAEVNLQSGN--NFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFF 266 Query: 151 VGGWLLGYNSFYDKVLSESLARGSVGAEAWGEYLRLSANYYHPLGDW-QLRDNQTQEQRM 209 + +LGYN F D+ S R +G E W +Y + S N Y + W + + + ++R Sbjct: 267 LPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERP 326 Query: 210 AAGYDVTAQARLPFYQHINTSVSVEQYFGDSVDLFHSGTGYHNPVAVSVGLNYTPVPLVT 269 A G+D+ LP Y + + EQY+GD+V LF+S NP A +VG+NYTP+PLVT Sbjct: 327 ANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVT 386 Query: 270 VTAKHKQGENGVSQNNVGLKLNYRFGVPLKQQLAADEVAISNSLRGSRFDSPERDNLPVV 329 + ++ G + ++ Y+F P QQ+ V +L GSR+D +R+N ++ Sbjct: 387 MGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIIL 446 Query: 330 EYRQRKNLTVYLATP-PWDLQSGETVQLKLQIHSLHGIKALHWQGDTQALSLTPPVDASS 388 EY +K + L P + T +++L + S +G+ + W D+ S + S Sbjct: 447 EY--KKQDILSLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWD-DSALRSQGGQIQHSG 503 Query: 389 PDG---WSIIMPVWNSEPGAANRWRLSVVVEDKQGQRVSSNEIALALT 433 + I+P + G +N ++++ D+ G SSN + L +T Sbjct: 504 SQSAQDYQAILPAYV--QGGSNVYKVTARAYDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.5 bits (183), Expect = 8e-18 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 2/118 (1%) Query: 6 RATILLIDDHPMLRTGVKQLISMAPDIQVIGEASNGAQGIELAESLDPDLILLDLNMPGM 65 ATIL+ DD +RT + Q +S A V SN A + D DL++ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 66 NGLETLDKLREKSLSGRVVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQA 123 N + L ++++ V+V S N + A ++GA YL K + +L+ + +A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 48.3 bits (115), Expect = 5e-08 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 9/116 (7%) Query: 476 FGFTVQLDYQLPPRFVPSHQAIHLLQIAREALSNALKHASAT-----EVTVTVSQRDNQV 530 F +Q + Q+ P + L+Q E N +KH A ++ + ++ + V Sbjct: 236 FEDRLQFENQINPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTV 292 Query: 531 RLVVADNGRGVPDHAERSNHYGLIIMRDRAQSLRG-DCQVRRRETGGTEVIVTFIP 585 L V + G + + S GL +R+R Q L G + Q++ E G + IP Sbjct: 293 TLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 52/282 (18%), Positives = 93/282 (32%), Gaps = 49/282 (17%) Query: 128 TPFSIFVIISLLCGFAGANF-ASSMANISFFFPKAKQGGALGVNGGLGNMGVSVMQLVAP 186 + FS+ ++ + G A F A M ++ + PK +G A G+ G + MG V + Sbjct: 101 SFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG 160 Query: 187 ------------LVVSISIFAVFGGNGSEQPDGS--------------------MLYLEN 214 L+ I+I V + + ML+ + Sbjct: 161 MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS 220 Query: 215 AAWIWVPFLIIFTLAAWFFMNDLSASK-----ASLSEQLPVLKRLHLWIMALLYLATFGS 269 + FLI+ L+ F+ + L + +P + + + +A F S Sbjct: 221 YSIS---FLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS 277 Query: 270 FIGFSAGFAM-LSKTQFPDVQILHYAFFGPFIGALARSMGGAISDRLGGTRVTLVNFVVM 328 + + LS + V I G + GG + DR G V + + Sbjct: 278 MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI----GGILVDRRGPLYVLNIGVTFL 333 Query: 329 AVFCALLFLTLPTNGQGGNFIAFFAVFMVLFLTAGLGSASTF 370 +V L T F+ VF++ L+ ST Sbjct: 334 SVSFLTASFLLETTSW---FMTIIIVFVLGGLSFTKTVISTI 372
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 8e-04 Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 19/155 (12%) Query: 17 LFMFFFIPGLLMASWATRTPAIRDLLALSTAEMGVVLFGLSVGSMSGILCS---AWLVKR 73 + I G + + ++D+ LSTAE+G V+ + G+MS I+ LV R Sbjct: 262 VLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI--IFPGTMSVIIFGYIGGILVDR 319 Query: 74 FGTRKVIRTTM-----SFAVLGMLVLSLALWVTSAPLFAFGLAIFGASFGSAEVAINVEG 128 G V+ + SF L+ + + ++T +F G F + S V+ +++ Sbjct: 320 RGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQ 379 Query: 129 AAIEREMNKTVLPMMHGFYSFGTLFGAGVGMAVTG 163 M +F + G G+A+ G Sbjct: 380 QEAGAGM---------SLLNFTSFLSEGTGIAIVG 405 Score = 30.2 bits (68), Expect = 0.016 Identities = 30/150 (20%), Positives = 63/150 (42%), Gaps = 6/150 (4%) Query: 218 LLIGVIVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTLGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVAVVRGSAV---MGALGIGLIIFVDNPWVAGISVLLWGIGASLGFPLTISAASDT 332 DR + V+ + L ++ + ++ I V + G + ++ +S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 333 GP-DAPKRVSVVAITGYLAFLVGPPLLGFL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.8 bits (106), Expect = 4e-07 Identities = 61/267 (22%), Positives = 106/267 (39%), Gaps = 19/267 (7%) Query: 71 LLGPLSDRIGRRPVMLTGVVWFIVTCLATLLAQTIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVGAAWVHVLPWEMMFVLFAVLAAISFFGLQR 190 + + + M+ + GP++G P F A L ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCF 179 Query: 191 AMPET--ATRLGEKLSVKELGRDYRLVLKNLRFVAGALATGFVSLPLLAWIAQSP--VII 246 +PE+ R + +R + + VA +A F ++ + Q P + + Sbjct: 180 LLPESHKGERRPLRREALNPLASFRWA-RGMTVVAALMAVFF----IMQLVGQVPAALWV 234 Query: 247 ISGEQATSYEYGMLQVPI--FGAL--IAGNLVLARLTARRTVRSLIIMGGWPIMFGLILS 302 I GE ++ + + + FG L +A ++ + AR R +++G G IL Sbjct: 235 IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILL 294 Query: 303 AAATVVSSHAYLWMTAGLSFYAFGIGL 329 A AT ++ + + GIG+ Sbjct: 295 AFAT----RGWMAFPIMVLLASGGIGM 317
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 34.8 bits (80), Expect = 4e-04 Identities = 44/192 (22%), Positives = 70/192 (36%), Gaps = 24/192 (12%) Query: 15 CALLFLVAPAV-QAAEQLPDAPS-IDAR-AWILMDYASGKVLSEGNADEKLDPASLTKIM 71 A L L A Q EQ+ + S + R I MD ASG+ L+ ADE+ S K++ Sbjct: 12 LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVV 71 Query: 72 TSYVVGQAIKAGKIKLTDMVTVGRDAWATGNPALRGSSVMFLKPGMQVSVEDLNKGVIIQ 131 V + AG +L + + +P L GM +V +L I Sbjct: 72 LCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSE----KHLADGM--TVGELCAAAITM 125 Query: 132 SGNDASIAIADYVAGSQDAFVSLMNGYAKKMGLTNTTFMTVH-----GLDAPGQF---ST 183 S N A+ + V G + + +++G + PG +T Sbjct: 126 SDNSAANLLLATVGGPAG-----LTAFLRQIG--DNVTRLDRWETELNEALPGDARDTTT 178 Query: 184 ARDMALLTKALI 195 MA + L+ Sbjct: 179 PASMAATLRKLL 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 5e-14 Identities = 16/74 (21%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Query: 4 KGEQAKNQLIAAAIAQFGEYGQHATT-RDIAAQAGQNIAAITYYFGSKDDLYLACAQWIA 62 + ++ + ++ A+ F + G +T+ +IA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 63 DFIGDNFARRPKRR 76 IG+ + Sbjct: 68 SNIGELELEYQAKF 81
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 76.4 bits (188), Expect = 1e-17 Identities = 49/290 (16%), Positives = 107/290 (36%), Gaps = 26/290 (8%) Query: 55 ASLTVDEGDSIRAGQTLGELDRAPYENALLQAQANVSTAQAQYDLMMAGYRAEEIAQAAA 114 V E + +R + E + ++N Q + N+ +A+ ++A E Sbjct: 175 YFQNVSEEEVLRLTSLIKE-QFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 115 AVKQAQAAYDYAQNFYQRQ--LGLRASSAISANDLENARSSRDQAQATLKSAQDKLRQYR 172 + + + + L + N+L +S +Q ++ + SA+++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 173 AGNRPQ---EIAQAKASLEQAQAALAQAKLDLHDTVLTAPSDGTLMTRAV-EPGTMLNAG 228 + + ++ Q ++ LA+ + +V+ AP + V G ++ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 229 GTVLTLSLT-HPVWVRAYVDEKNLGQAQPGQEVLLYTDSRPDKPYH---GKIGFVSPSAE 284 T++ + + V A V K++G GQ ++ ++ P Y GK+ ++ A Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA- 412 Query: 285 FTPKTVETPDLRTDLVYRLRIVVTDADGA-------LRQGMPVTISFSHG 327 D R LV+ + I + + + L GM VT G Sbjct: 413 -------IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.019 Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 30 IRAGYVTGLVGPDGAGKTTLMRMLAGL 56 + Y L G G GK+TL+ L GL Sbjct: 593 CKFDYSVVLEGTGGIGKSTLINTLVGL 619
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 45.3 bits (107), Expect = 2e-07 Identities = 31/137 (22%), Positives = 56/137 (40%), Gaps = 1/137 (0%) Query: 197 AREREQGTLDQLLVSPLATWQIFVGKAVPALIVATLQATIVLAIGIWAYQIPFAGSLLLF 256 R Q T + +L + L I +G+ A A L + + + SLL Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL-SLLYA 150 Query: 257 YFTMVIYGLSLVGFGLLISSLCATQQQAFIGVFVFMMPAILLSGYVSPVENMPQWLQNLT 316 + + GL+ G+++++L + + + P + LSG V PV+ +P Q Sbjct: 151 LPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAA 210 Query: 317 WINPIRHFTDITKQIYL 333 P+ H D+ + I L Sbjct: 211 RFLPLSHSIDLIRPIML 227
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 30.1 bits (68), Expect = 0.033 Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 14/76 (18%) Query: 4 TATLILTHGQIHTLDRANPLAEAVAIADGKIVATGS------HDRIMSFAAEGTQIVDLK 57 T LIL H I D + + DG+I A G + GT+++ + Sbjct: 73 TNALILDHWGIVKAD--------IGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGE 124 Query: 58 GHTVIPGLNDSHLHLI 73 G V G DSH+H I Sbjct: 125 GKIVTAGGMDSHIHFI 140
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 36.1 bits (83), Expect = 6e-05 Identities = 35/186 (18%), Positives = 67/186 (36%), Gaps = 21/186 (11%) Query: 7 LDPTNSALIFIDHQPQM--SFGVANIDRQTLKNNTVALAKAGKIFNVPVIYT------SV 58 DP + L+ D Q +F L N L +PV+YT + Sbjct: 26 PDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNP 85 Query: 59 ETKSFSGYIW-PELLAVHPDVKPIERTS-------MNSWEDDAF-----VAAVKATGRKK 105 + ++ W P L + + K I + + W AF + ++ GR + Sbjct: 86 DDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQ 145 Query: 106 LVISALWTEVCLTFPALMALEAGYEVYVVTDTSGGTSVDAHERSIDRMVQAGAVPVTWQQ 165 L+I+ ++ + A A + + V D S++ H+ +++ A V Sbjct: 146 LIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDS 205 Query: 166 VLLEYQ 171 +L + Q Sbjct: 206 LLDQLQ 211
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.030 Identities = 17/75 (22%), Positives = 29/75 (38%) Query: 357 FLVIASLATFATVWVWIMILLSQIAFRRRLSPEEVKALKFKVPGGVVTTVIGLLFLAFII 416 F A+L + ++ S RR L E + L +T V L+ + FI+ Sbjct: 163 FFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIM 222 Query: 417 ALIGYHPDTRISLYV 431 L+G P ++ Sbjct: 223 QLVGQVPAALWVIFG 237
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.006 Identities = 16/98 (16%), Positives = 30/98 (30%), Gaps = 25/98 (25%) Query: 325 LVYNAVNH----TPPGTEIRVSWQRTPQGALFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P G +I + + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HDSRLEIDSTVGKGT 415 +G GL V+ + ++++++ GK Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.7 bits (238), Expect = 5e-25 Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGLQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKLLKREAMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPSSHRVMTGDSP 152 E L D + G S Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 4e-04 Identities = 26/207 (12%), Positives = 54/207 (26%), Gaps = 23/207 (11%) Query: 196 ARHALEKFEAQAAGIVLLTEAQQQALQESLQVLTDEEKALLAQQQSQQQQLQWLTRRDEL 255 A K ++ L + + Q L S+++ E L + Q + + R L Sbjct: 132 AEADTLKTQSSLL-QARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 256 AQQQQQAATRQQ-QARQALADAAPALAKLE------------LAQPAAQLRPLWERQQEQ 302 ++Q Q+ Q L + L +Q Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 303 TAGLAQTRQRISEVNARLLASTALRARIRQGALRAQQQRQAELADLAQWLAAHERFRLWG 362 + + + E L + +I L A+++ Q L Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ---------LVTQLFKNEIL 301 Query: 363 QEIAGWRAQFSQLTRDKQQLTAQSTRL 389 ++ LT + + + Sbjct: 302 DKLRQTTDNIGLLTLELAKNEERQQAS 328 Score = 34.8 bits (80), Expect = 0.002 Identities = 26/204 (12%), Positives = 64/204 (31%), Gaps = 23/204 (11%) Query: 308 QTRQRISEVNARLLASTALRARIRQGALRAQQQRQAELADLAQWLAAHERFRLWGQEIAG 367 + + LL + + R + + + + EL + + + + Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 368 WRAQFSQLTRDKQQLTAQSTRLAALRQKLATLPASPLTLSADDVAAAIEQQTQS--RPL- 424 + QFS K Q L R + T+ A ++ + + +E+ L Sbjct: 191 IKEQFSTWQNQKYQKELN---LDKKRAERLTVLA---RINRYENLSRVEKSRLDDFSSLL 244 Query: 425 ------RQRLLSLHEQHQLLRKRLRQNADSVQQAQAEQVKLNATLTLRREQYKDKNQHYL 478 + +L ++ LR ++Q ++E + L + +K+ Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN------ 298 Query: 479 DLKALCQREETIKDLESYRDRLEA 502 + L + +T ++ L Sbjct: 299 --EILDKLRQTTDNIGLLTLELAK 320 Score = 32.5 bits (74), Expect = 0.009 Identities = 37/294 (12%), Positives = 88/294 (29%), Gaps = 52/294 (17%) Query: 418 QTQSRPLRQRLLSLHEQHQLLRKRLRQNADSVQQAQAEQVKLNATLTLRREQYKDKNQHY 477 + + S Q +L + R + + S++ + ++KL + ++ + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 478 LDLKALCQREETIKDLESYRDRLEAGKPCPLCGACEHPAIEQYASLTLTDNQRRRDALEK 537 +K +++++ + L L + R + Sbjct: 189 SLIKE---------QFSTWQNQKYQKE------------------LNLDKKRAERLTVLA 221 Query: 538 EVAALKEEGLLILGQVKALTQQLQRDTEAAGRLAEEEQALTKAWQETCASLHITRDIAQE 597 + + + ++ + L + A + E+E +A E L + + ++ Sbjct: 222 RINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNE----LRVYKSQLEQ 277 Query: 598 INDWMQEQERYEQQLYQLSQRLMLQSQLNDQQALERQAEQQLAATRQGLESALQALALSL 657 I + + Q + QL + +L +L +LA + QA + Sbjct: 278 IESEILSAKEEYQLVTQLFKNEIL-DKLRQTTDNIGLLTLELAKNEE----RQQASVIRA 332 Query: 658 PAEGTEAAWLHARESEFAQWQAQQTQHDAIQQQIAALRPLLETLPTSDETEVEA 711 P QQ + + L+ +P D EV A Sbjct: 333 PVSVK----------------VQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Score = 31.7 bits (72), Expect = 0.018 Identities = 40/206 (19%), Positives = 80/206 (38%), Gaps = 22/206 (10%) Query: 675 AQWQAQQTQHDAIQQQIAALRPLLETLPTSDETEVEAESAIPD-------NWREIHEECL 727 A+ +TQ +Q ++ R + L S E E +PD + E+ Sbjct: 132 AEADTLKTQSSLLQARLEQTR--YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTS 189 Query: 728 SLHSQLVAQQQQETQEKARLDQSQAQFTSALAASRFSDREAFLAALLDDETAQRLTQLKQ 787 + Q Q Q+ Q++ LD+ +A+ + LA + + + RL Sbjct: 190 LIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE-------KSRLDDFSS 242 Query: 788 TLEQQLQQAAALCEQATRQHEAHLALRPQGVDADVPTLQTQLHALAQRLRDNT-TRQGEI 846 L +Q A+ EQ + EA LR + + +++++ + + + T + EI Sbjct: 243 LLHKQAIAKHAVLEQENKYVEAVNELRVY--KSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 847 RQQLRQDAESRQQQQALGQQIAEAAQ 872 +LRQ + L ++A+ + Sbjct: 301 LDKLRQ---TTDNIGLLTLELAKNEE 323
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 33.6 bits (77), Expect = 8e-04 Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 216 EGDEKAELALSRYEQRLAKSLAHVVNILDP-DVIVLGGGM 254 GD++A+LAL+ + R+ K++ + DVIV G+ Sbjct: 293 NGDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGI 332
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 30.6 bits (69), Expect = 0.025 Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 11/90 (12%) Query: 208 DYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEA---MELSYFGAKV 264 D + LA + AD I TDV+G + L+ + +E E +F A Sbjct: 216 DLAGEKLAEEVNADIFMILTDVNGAAL-YYGT-EKEQWLREVKVEELRKYYEEGHFKAGS 273 Query: 265 LHPRTIAPIAQFQIPCLIKNTGNPQAPGTL 294 + P+ +A I +F I+ G L Sbjct: 274 MGPKVLAAI-RF-----IEWGGERAIIAHL 297
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 2e-20 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSENDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QADVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + D+ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 9e-05 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 20/94 (21%) Query: 379 AIDFTPQGGEIALAAEKRNEEVQLSVIDNGCGIPDYALERIFERFYSLPREDGHKSSGLG 438 I PQGG+I L K N V L V + G SL ++ +S+G G Sbjct: 271 GIAQLPQGGKILLKGTKDNGTVTLEVENTG----------------SLALKNTKESTGTG 314 Query: 439 LAFVREVARLHHGD---INLHNRPEGGVVATLRL 469 L VRE ++ +G I L + +G V A + + Sbjct: 315 LQNVRERLQMLYGTEAQIKLSEK-QGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.8 bits (246), Expect = 4e-26 Identities = 36/146 (24%), Positives = 64/146 (43%) Query: 1 MQQPRIWLVEDEQSIADTLVYMLQQEGFQVSVFGRGLPALEAAAHQAPDVAILDVGLPDI 60 M I + +D+ +I L L + G+ V + A D+ + DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRRLLTRYPALPVLFLTARSDEVDKLLGLEIGADDYIAKPFSPREVCARVRTVLR 120 + F+L R+ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RLQKFAAPSPVVRVGEFVLDEQAAAI 146 ++ + L ++AA+ Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAM 146
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 29.3 bits (65), Expect = 0.020 Identities = 20/97 (20%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 139 LGVTQSYTCKLEEISDFRNQMRVQFWRDFLGNSPS-IPPVLYGLHEPRPSLEK--DDEQE 195 +G S +++ D ++ + + G P + + G+ +P+ + DD+ + Sbjct: 24 IGAPPSAHAGADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWK 83 Query: 196 VFYTTALTPEMANGHLQHAHPVTLEGGEYVMFTYEGL 232 FY+T + A + + +P++ + G V TY GL Sbjct: 84 GFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGL 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 159 bits (403), Expect = 1e-43 Identities = 79/301 (26%), Positives = 132/301 (43%), Gaps = 27/301 (8%) Query: 86 MAELLAESDRQPEQADHFSLLTGHDGSLRKPIEQMKTALFYPNGGLPLLITGDSGTGKSY 145 +AE + + + L G ++++ + + L L+ITG+SGTGK Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM---QTDLTLMITGESGTGKEL 175 Query: 146 MAELMHEFAIAQGLLAPDAPFVSFNCAQYASNPELLAANLFGYVKGAFTGAQSDKAGAFE 205 +A +H++ + + PFV+ N A A +L+ + LFG+ KGAFTGAQ+ G FE Sbjct: 176 VARALHDYGKRR-----NGPFVAINMA--AIPRDLIESELFGHEKGAFTGAQTRSTGRFE 228 Query: 206 AANGGMLFLDEVHRLDAQGQEKLFTWLDRKEIYRVGETAQGLPISLRLVFATTEDIHS-- 263 A GG LFLDE+ + Q +L L + E VG + +R+V AT +D+ Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGR-TPIRSDVRIVAATNKDLKQSI 287 Query: 264 ---TFLTTFLRRIPIL-VSLPDLQHRSREEKEALTLQFFWQEARTLAAR-LQLTPRLLQV 318 F R+ ++ + LP L R R E ++ F Q+A + L++ Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPL--RDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALEL 345 Query: 319 LTQYVYRGNVGELKNVVKYAVASAWARSPGREMLTVTLHDLPENVMAATPALSEAMGQQE 378 + + + GNV EL+N+V+ A P +T + + + P Sbjct: 346 MKAHPWPGNVRELENLVRRLT----ALYPQD---VITREIIENELRSEIPDSPIEKAAAR 398 Query: 379 P 379 Sbjct: 399 S 399
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 2e-08 Identities = 71/402 (17%), Positives = 147/402 (36%), Gaps = 39/402 (9%) Query: 44 MILLFLAAVINYLDRSSLSVANLTIRQELGLNATEIGALLSVFSLAYGIAQLPCGPLLDR 103 +I L + + + L+ L+V+ I + + + F L + I G L D+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 104 KGPRIMLGLGMFFWSLFQALSGMVHSFTQF-VLVRIGMGIGEAPMNPCGVKVINDWFNIK 162 G + +L G+ + + HSF ++ R G G A + V+ + + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 163 ERGRPMGFFNAASTIGVAVSPPILAAMMLMMGWRWMFIT--------------------- 201 RG+ G + +G V P I + + W ++ + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 202 ------IGILGIFIAIGWYMLYRNREDLPLTADEQAYLNAGSVNVRRDPLSFAEWRSLFK 255 GI+ + + I ++ML+ + ++R+ F + L K Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPG-LGK 254 Query: 256 NKT-MWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGFMAAIPFLFGAAGMLING 314 N M G++ G I T +++ +P ++ + L G + P G ++I G Sbjct: 255 NIPFMIGVLCGGI-IFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP---GTMSVIIFG 310 Query: 315 YVTDWLV-KGGMAPIKSRKICIIAGMFCSAAFTLIVPHATTSFAAVLLIGMALFCIHFAG 373 Y+ LV + G + + + ++ F +A+F L + V ++G F Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIS 370 Query: 374 TSCWGLIHVAVASRMTASVGSIQNFASFICASFAPVVTGFIV 415 T + ++ + + S+ NF SF+ + G ++ Sbjct: 371 TI----VSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 4e-05 Identities = 12/60 (20%), Positives = 23/60 (38%), Gaps = 4/60 (6%) Query: 80 ALRPAWRGKGLGRKLMQELLMLLQQQGIETVFLEVIRDNHAAVALYQSLGFTRRYGLCGY 139 A+ +R KG+G L+ + + ++ + LE N +A Y F + Sbjct: 96 AVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI----IGAV 151
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 1e-04 Identities = 21/93 (22%), Positives = 44/93 (47%), Gaps = 10/93 (10%) Query: 74 VGFI-LTEPLDDALFIVEVAVHQAWQQQGIGRMLLERVIESARQMGYPAVTLTTFREVPW 132 +G I + + I ++AV + ++++G+G LL + IE A++ + + L T +++ Sbjct: 77 IGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLET-QDI-- 133 Query: 133 NAP---FYTRLGFAM--LDELTLPAGLAAKREQ 160 N FY + F + +D L + E Sbjct: 134 NISACHFYAKHHFIIGAVD-TMLYSNFPTANEI 165
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 1e-20 Identities = 35/117 (29%), Positives = 61/117 (52%) Query: 2 KILIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTSDYDLLILDIMLPDVNGWD 61 IL+ +D+ L + L+ AG+ V + N + D DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRAAGKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 28.7 bits (64), Expect = 0.043 Identities = 10/40 (25%), Positives = 19/40 (47%), Gaps = 2/40 (5%) Query: 227 FVYGMSGLLSGLGGVMSASRLYSANGNLGVGYELDAIAAV 266 ++G+ + GG A R + N G+G + A+ A+ Sbjct: 400 LLHGLPAGWTIYGGTQLADRYRAF--NFGIGKNMGALGAL 437
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.4 bits (66), Expect = 0.019 Identities = 16/65 (24%), Positives = 25/65 (38%), Gaps = 5/65 (7%) Query: 55 KLAGDNVKVTLVSSGYDLGQQVAQIDNFIAAKVDMIIL---NAADSKGIGPAVKRAKEAG 111 L +KV + I I KVD+I + D + AVK+A + Sbjct: 111 DLLI--IKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEAVKKAVASQ 168 Query: 112 IVVVA 116 I+V+ Sbjct: 169 ILVMC 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 9e-23 Identities = 33/132 (25%), Positives = 62/132 (46%), Gaps = 1/132 (0%) Query: 2 KPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDTH 61 ILV DDD A+ +L+ L ++V ++ +A D LV+ D+++PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPDEN 61 Query: 62 GLQVLQQLQRTRPELPVVMLSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLRR 121 +L ++++ RP+LPV+++S + + E GA DY+ KPF ++ + L Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 SGALAGEASGAG 133 + Sbjct: 122 PKRRPSKLEDDS 133
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.8 bits (59), Expect = 0.035 Identities = 11/43 (25%), Positives = 14/43 (32%) Query: 102 GHRYGEHIFHAVETRAKTAGESWLWLEVLAANPAARRFYERQG 144 G + H AK L LE N +A FY + Sbjct: 103 KKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHH 145
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.007 Identities = 17/79 (21%), Positives = 34/79 (43%), Gaps = 13/79 (16%) Query: 69 LAKETDLAGAIKSMFSGEKINR-------TEDRAVLHVALRNRSNTPIVVDGKDVMPEVN 121 AK +DL + + S + + D+ ++ + ++N IV DVM ++ Sbjct: 276 YAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNII-IKAHGQTNALIVTAAPDVMNDLE 334 Query: 122 AVLEKM-----KTFSEAII 135 V+ ++ + EAII Sbjct: 335 RVIAQLDIRRPQVLVEAII 353
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 25.3 bits (55), Expect = 0.038 Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 2 ALPRITQKEMTEREQRELKTLLDRARIAHGRPLSNAETNSVKKEYIDKLMAQREAEAKKA 61 LP E + + +EL L+ R + ++NA N + ++ AQ++ Sbjct: 290 GLPNSASIEQIQSKIQELGDTLEELRDSFDGYINNAFVNQIHLNFVMPPQAQQQQG---- 345 Query: 62 RQVRKQQAYKTDKEA 76 Q ++QQA T +EA Sbjct: 346 -QGQQQQAQATAQEA 359
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.045 Identities = 6/21 (28%), Positives = 12/21 (57%) Query: 26 QAQIARELGIYRTTISRLLKR 46 Q + A LG+ R T+ + ++ Sbjct: 452 QIKAADLLGLNRNTLRKKIRE 472
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (289), Expect = 4e-33 Identities = 79/271 (29%), Positives = 126/271 (46%), Gaps = 26/271 (9%) Query: 7 LKDNVIIVTGGASGIGLAIVDELLSQGAHVQMIDIHGGDRHHNGDNYHF-------WPTD 59 ++ + +TG A GIG A+ L SQGAH+ +D + + +P D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 60 ISSATEVQQTIDAIIQRWSRIDGLVNNAGVNFPRLLVDEKAPAGRYELNEAAFEKMVNIN 119 + + + + I + ID LVN AGV P L+ + L++ +E ++N Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLI---------HSLSDEEWEATFSVN 116 Query: 120 QKGVFFMSQAVARQMVKQRAGVIVNVSSESGLEGSEGQSCYAATKAALNSFTRSWSKELG 179 GVF S++V++ M+ +R+G IV V S + YA++KAA FT+ EL Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 180 KYGIRVVGVAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYT---KNAIPIGRAGKLS 236 +Y IR V+PG E + W EQ+ +G K IP+ + K S Sbjct: 177 EYNIRCNIVSPGSTETDMQWS-------LWADENGAEQVIKGSLETFKTGIPLKKLAKPS 229 Query: 237 EVADFVCYLLSARASYITGVTTNIAGGKTRG 267 ++AD V +L+S +A +IT + GG T G Sbjct: 230 DIADAVLFLVSGQAGHITMHNLCVDGGATLG 260