>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.9 bits (69), Expect = 0.036 Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 19/173 (10%) Query: 121 QEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFEKY---SQALKSNYIQYISIK 177 Q+ S+ ++ + + EK+ F+ E+ + + Y S+ K Y + Sbjct: 118 QDLSEEEKNSMNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGI 177 Query: 178 ITTIFSQINILDFEY-----SKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLE 232 I S+ LD E+ S + D L++ +E K + K I+++ ++ Sbjct: 178 SLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKE-KLELNNKSIDINF-----IK 231 Query: 233 LTVESFMESIAK-----FDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLK 280 + F + + F + VL+ Y PD +EY+ KL E++ + LK Sbjct: 232 ENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFEKISESLK 284
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.8 bits (69), Expect = 0.004 Identities = 30/190 (15%), Positives = 57/190 (30%), Gaps = 3/190 (1%) Query: 55 KENEKISGLENANDQLWQAKDKLTKENTELTHKNAVLTEKTAELKTENDKLNHLVIALNN 114 K + + L+ N L L N ELT + + EK + + + L Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEA 120 Query: 115 EQGSLKQERAKLQDEHGFLEKRCTNLEKENQRLTDKLKQLESAQKNLENSKNQLLQAREK 174 + L++ + + LE E L + LE A + N + Sbjct: 121 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 180 Query: 175 IAEEKTELEREMARLKSLEATDKSELDLQNRR---FKSAIEDLKRQNRKLEEENIALKER 231 + EK LE A L+ + + + ++ L + LE+ Sbjct: 181 LEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 240 Query: 232 VDGLKEQLSK 241 ++ Sbjct: 241 STADSAKIKT 250 Score = 30.4 bits (68), Expect = 0.006 Identities = 40/234 (17%), Positives = 84/234 (35%), Gaps = 6/234 (2%) Query: 16 EELEDRIGELENENAELFTTKEKLTKENTDLAYKNNKLFKENEKISGLENANDQLWQAKD 75 E++++R + E EN L L+ N L N++L +E + + ++ Sbjct: 53 EKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELS---NAKEKLRKNDKSLS 109 Query: 76 KLTKENTELTHKNAVLTEKTAELKTENDKLNHLVIALNNEQGSLKQERAKLQDEHGFLEK 135 + + EL + A L + + + + L E+ +L +A L+ Sbjct: 110 EKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 169 Query: 136 RCTNLEKENQRLTDKLKQLESAQKNLENSKNQLLQAREKIAEEKTELEREMARLKSLEAT 195 T + + L + LE+ Q LE + + + + LE E A L + +A Sbjct: 170 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 229 Query: 196 ---DKSELDLQNRRFKSAIEDLKRQNRKLEEENIALKERVDGLKEQLSKQPKPQ 246 + + I+ L+ + LE L++ ++G + Sbjct: 230 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Score = 30.0 bits (67), Expect = 0.008 Identities = 36/175 (20%), Positives = 57/175 (32%), Gaps = 3/175 (1%) Query: 16 EELEDRIGELENENAELFTTKEKLTKENTDLAYKNNKLFKENEKISGLENANDQLWQAKD 75 + LE L A+L E +T + K L E LE +L +A + Sbjct: 144 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA---LEARQAELEKALE 200 Query: 76 KLTKENTELTHKNAVLTEKTAELKTENDKLNHLVIALNNEQGSLKQERAKLQDEHGFLEK 135 +T + K L + A L L + N + + L+ E LE Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 260 Query: 136 RCTNLEKENQRLTDKLKQLESAQKNLENSKNQLLQAREKIAEEKTELEREMARLK 190 R LEK + + + K LE K L + + + L L+ Sbjct: 261 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLR 315 Score = 28.9 bits (64), Expect = 0.023 Identities = 42/237 (17%), Positives = 79/237 (33%), Gaps = 7/237 (2%) Query: 12 SQIREELEDRIGELENENAELFTTKEKLTKENTDLAYKNNKLFKENEKISGLENANDQLW 71 + + + LE K+ + A + + + G N + Sbjct: 186 AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADS 245 Query: 72 QAKDKLTKENTELTHKNAVLTEKTAELKTENDKLNHLVIALNNEQGSLKQERAKLQDEHG 131 L E L + A L + + + + L E+ +L+ E+A L+ + Sbjct: 246 AKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQ 305 Query: 132 FLEKRCTNLEKENQRLTDKLKQLESAQKNLENSKNQLLQAR-------EKIAEEKTELER 184 L +L ++ + KQLE+ + LE +R + E K +LE Sbjct: 306 VLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEA 365 Query: 185 EMARLKSLEATDKSELDLQNRRFKSAIEDLKRQNRKLEEENIALKERVDGLKEQLSK 241 E +L+ ++ R ++ E K+ + LEE N L KE Sbjct: 366 EHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1045 bits (2703), Expect = 0.0 Identities = 354/569 (62%), Positives = 443/569 (77%), Gaps = 4/569 (0%) Query: 3 KISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSN-NP 61 ++SR Y +M+GPT GDKVRL DT+L EVE D+T +GEE+KFGGGK +R+GM QS Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 SKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEAL 121 +D +ITNALI+D+ GI KADIG+KDG+IA IGK GN DMQ GV + VGP TE + Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGV--TIIVGPGTEVI 121 Query: 122 AGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKW 181 AGEG IVTAGG+D+HIHFI PQQI A SG+T M+GGGTGPA GT ATT TPG ++ Sbjct: 122 AGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIAR 181 Query: 182 MLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKY 241 M+ AA+ + MNL F KGNAS +L + + GA K+HEDWGTTP+AI+ L VAD+Y Sbjct: 182 MIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEY 241 Query: 242 DVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTN 301 DVQV IHTDTLNE+G VEDT+AAI GRT+H +HTEGAGGGHAPDII++ G+ N++P+STN Sbjct: 242 DVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTN 301 Query: 302 PTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSS 361 PT P+TVNT AEH+DMLMVCHHL +I ED+ FA+SRIR +TIAAED LHD+G FSI SS Sbjct: 302 PTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISS 361 Query: 362 DSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISE 421 DSQAMGRVGEV RTWQTADK K++ GRLKEE GDNDNFR+KRY++KYTINPAIAHG+S Sbjct: 362 DSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSH 421 Query: 422 YVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAH 481 +GS+EVGK ADLVLW+PAFFGVKP+M++ GG IA + MGD NASIPTPQPV+YR MF Sbjct: 422 EIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGA 481 Query: 482 HGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCR-NITKKDMQFNDTTAHIEVNP 540 +G+++ ++++TFVSQA+ D G+ LG+ ++++ V+N R I K M N T HIEV+P Sbjct: 482 YGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDP 541 Query: 541 ETYHVFVDGKEVTSKPANKVSLAQLFSIF 569 ETY V DG+ +T +PA + +AQ + +F Sbjct: 542 ETYEVRADGELLTCEPATVLPMAQRYFLF 570
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 29.9 bits (67), Expect = 0.032 Identities = 17/46 (36%), Positives = 24/46 (52%), Gaps = 3/46 (6%) Query: 499 NADTGNTDTGNTDTGNTDDASNMNNG---NDDAGNANDDMSNGNDM 541 NAD+ +T NT+T T++ + + AG DDM N NDM Sbjct: 33 NADSNKQNTANTETTTTNEQPKPESSELTTEKAGQKMDDMLNSNDM 78
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 5e-07 Identities = 55/271 (20%), Positives = 103/271 (38%), Gaps = 16/271 (5%) Query: 28 LILSGSLTPHQSFQLGIAVLMGYVFGSFLIQFLSPLMSLESIAKISFGLIALSFLICYFD 87 L+ S +T H L + LM + L LS + +S A+ + I Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGA-LSDRFGRRPVLLVSLAGAAVDYAI--MA 91 Query: 88 SIPFFW-LWIWRFIAGVASSALMILVAPLSLPYVKENKRALVGGFIFSAVGIGSVFSGFV 146 + PF W L+I R +AG+ + A + ++RA GF+ + G G V + Sbjct: 92 TAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 147 LPWISSYNIKWAWIFLGGSCLIAFILSLTGLKN-HSLKKKSVKKEESAFKIPFHL----- 200 + ++ + + F+ L H +++ +++E F Sbjct: 151 GGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMT 210 Query: 201 ---WLLLISCALNAIGFLPHTLFWVDYLIRHLNISPAIAGTSWAFFG-FGATLGSLISGP 256 L+ + + +G +P L WV + + G S A FG + ++I+GP Sbjct: 211 VVAALMAVFFIMQLVGQVPAAL-WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 257 MAQKLGAKNANIFILILKSIACFLPIFFHQI 287 +A +LG + A + +I L F + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRG 300
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.011 Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 8 LILSGPSGAGKSTLTKYL 25 ++L G G GKSTL L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 72.8 bits (178), Expect = 1e-15 Identities = 41/218 (18%), Positives = 78/218 (35%), Gaps = 18/218 (8%) Query: 162 LPTLNDQEEKEEEKEEVKETPQEEEKPKDNEIQEGETLKDEEVSKELETQ-------EEV 214 P+ + E K+E K + E+ + Q E K+ + + + TQ Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 215 KEETQEQAKEQEPIKEETQEIKEEKQEKTQDSPSAQELEAMQELVKEIQENSNGQEDKKE 274 +ETQ ++ E+ ++ K E ++ + ++ QE + +Q + + Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 275 TQESTEAPQEKETQENTEIPQETEKQELETPQEEKQESTETPQEKTQDVEIPQETPQENT 334 T E + T +TE P + +E P E VE P+ T T Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSV----VENPENTTPATT 1207 Query: 335 ETPQESTETPQKETQEKKVQENHYESIEDIPEPVMAQA 372 + P ++E+ K + H S+ +P V Sbjct: 1208 Q-PTVNSES------SNKPKNRHRRSVRSVPHNVEPAT 1238 Score = 52.4 bits (125), Expect = 3e-09 Identities = 45/261 (17%), Positives = 93/261 (35%), Gaps = 16/261 (6%) Query: 199 LKDEEVSKELETQEEVKEETQEQAKEQEPIKEETQEIKEEKQEKTQDSPSAQELEAMQEL 258 L + EV K +T + T + P E E P+ E Sbjct: 980 LYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 259 VKEIQENSNGQEDKKETQESTEAPQEKE--TQENTEIPQETEKQELETPQEEKQESTETP 316 V E + + +K E + Q +E + + + T+ E+ E +E+ T Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 317 QEKTQDVEIPQETPQENTET---PQESTETPQKETQEKKVQ--------ENHYESIEDIP 365 ++T VE ++ E +T P+ +++ K+ Q + VQ + +I++ Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 366 EPVMAQAMGEALPFLNESVAKIPNNENDTETPKKSVIKTPQEKEGSDKTSSPLELRLNLQ 425 A E S + P E+ T SV++ P+ + + Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP---TVNSESS 1216 Query: 426 DLLKSLNQESLKNLLENKTLS 446 + K+ ++ S++++ N + Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPA 1237 Score = 42.4 bits (99), Expect = 4e-06 Identities = 23/168 (13%), Positives = 47/168 (27%) Query: 148 KALVQEEPNNEEQLLPTLNDQEEKEEEKEEVKETPQEEEKPKDNEIQEGETLKDEEVSKE 207 A E + EKEE+ + E QE K + E + + E Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 208 LETQEEVKEETQEQAKEQEPIKEETQEIKEEKQEKTQDSPSAQELEAMQELVKEIQENSN 267 + + +E + + Q KE Q + + +V+ + + Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTP 1204 Query: 268 GQEDKKETQESTEAPQEKETQENTEIPQETEKQELETPQEEKQESTET 315 ES+ P+ + + +P E + + Sbjct: 1205 ATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 193 bits (492), Expect = 4e-64 Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 56 GERPLFADRRAMKPNDLITIIVSEKASANYSSS----KDYKSASGGNSTPPRLTYNGLDE 111 G +PLF DRR D +TI++ E SA+ SSS +D K+ G ++ P L GL Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYL--QGLFG 118 Query: 112 RKKQEAEYLDDKNNYNFTKSSNNTNFKGGGSQKKSEDLEIVLSARIIKVLENGNYFIYGN 171 + + E S F G G S L+ + +VL NGN + G Sbjct: 119 NARADVEA------------SGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGE 166 Query: 172 KEVLVDGEKQILKVSGVIRPYDIERNNTIQSKFLADAKIEYTNLGHLSDSNK 223 K++ ++ + ++ SGV+ P I +NT+ S +ADA+IEY G+++++ Sbjct: 167 KQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN 218
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.017 Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 102 RGETILKALEYIAFE---EFQLNSLHLEVMENNFKAIAFYEKNHYELEG 147 R + + AL + A E E L LE + N A FY K+H+ + Sbjct: 102 RKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.009 Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 30 VVALLGESGAGKSTILRILAGLE 52 V L G G GKST++ L GL+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 198 bits (505), Expect = 1e-57 Identities = 116/461 (25%), Positives = 190/461 (41%), Gaps = 67/461 (14%) Query: 3 NIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDE--RVMDSNDLERERGITILSKNT 60 I NI V+AHVD GKTTL + LL SG +E VD+ D+ LER+RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIYYKDTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI 120 + +++TK+NIIDTPGH DF EV R L ++DG +LL+ A++GV QT+ + GI Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 CPIVVVNKIDKPAAEPDRVVDEVFDLF---------VAMGASDKQLDFPV-----VYAAA 166 I +NKID+ + V ++ + V + + +F Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 167 RDGYAMKSLDDE----------------------------KKNL--EPLFETILEHVPSP 196 D K + + K N+ + L E I S Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMKSDGSKENGRITKLTGF 256 + L ++F ++Y ++ R+++G + +SV + KE +IT++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRI----SEKEKIKITEMYTS 297 Query: 257 LGLARTEIENAYAGDIVALAG--FNAMDV-GDSVVDPTNPMPLDPMHLEEPTMSVYFAVN 313 + +I+ AY+G+IV L V GD+ + P +P P + + Sbjct: 298 INGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----LPLLQTTVEPS 353 Query: 314 DSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRR 373 + + D LL+ + + +S G++Q+ + L+ Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSAT--------HEIILSFLGKVQMEVTCALLQE 405 Query: 374 E-GFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAI 413 + E I P VI E K E H+ + P F +I Sbjct: 406 KYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 41.8 bits (98), Expect = 8e-06 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 396 EPFEHLVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLT 455 EP+ I PQ++ K A + + + L EIPAR + YRS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 456 DTKGEGVMNHSFLEFRPFSG 475 T G V + +G Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.0 bits (67), Expect = 0.044 Identities = 33/144 (22%), Positives = 48/144 (33%), Gaps = 6/144 (4%) Query: 17 VDYGNKRVGLNNTWNNKDLENHWVISSYELRDTTEKPTHFPTSQAITKEKDIHSLNSVEP 76 VD G + L N DL N E R+ T T+ T I + N+ E Sbjct: 962 VDLGAWKYKLRNVNGRYDLYN----PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI 1017 Query: 77 NPTTNELKTQDLSPLEQARAEKLAK-LESEKLESEKEFLKAKEQE-QQRKAALKKKLEHE 134 E +A+ + E EK A E Q R+ A + K + Sbjct: 1018 ARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVK 1077 Query: 135 RGNAGNIESQTKIEVGEDIPTQTQ 158 N +Q+ E E T+T+ Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETK 1101
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.8 bits (59), Expect = 0.002 Identities = 12/32 (37%), Positives = 19/32 (59%), Gaps = 4/32 (12%) Query: 1 MKIIRNSVFIGASLLGGCASV----ETRFDSL 28 MK+ +++ +G +LL GCAS + R D L Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPL 32
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.044 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 51 TPKNILMIGSTGVGKTEIARRI---AKIMKLPFVKV 83 T +++ G +G GK +AR + K PFV + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>PF03944#delta endotoxin Length = 633 Score = 30.4 bits (68), Expect = 0.009 Identities = 24/94 (25%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 68 LHHQEKLLNQCMLSQALKAMGDAELCVFLASVHDDLKGYEEFLSLCQKPHILALSKIDTA 127 L E+ LNQ + + + A +AEL A+V + + + FL+ + L+++ Sbjct: 94 LRETERFLNQRLNTDTV-ARVNAELTGLQANVEEFNRQVDNFLNPNRNAVPLSITSSVNT 152 Query: 128 THKQVLQKLQEYQQYASQFVDLVPLSAKKSQNLN 161 + L +L ++Q Q + L+PL A+ + NL+ Sbjct: 153 MQQLFLNRLPQFQMQGYQLL-LLPLFAQAA-NLH 184
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.009 Identities = 32/183 (17%), Positives = 59/183 (32%), Gaps = 9/183 (4%) Query: 224 DEVCSPLRDEMVAMPTNDSVTQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKE 283 D P +E +A + P P N+ E++ Q A E + + Sbjct: 1006 DVPSVPSNNEEIARVDE-APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ 1064 Query: 284 KLIEELIANSQLVANEEEREKKLLAEKEKQEAELAKYKLKDLENQKKLKALEAELKKKNA 343 A S + AN + E + K+ + +E ++K K +K Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK----VETEKTQ 1120 Query: 344 KKPRVVEVPIPHQTSDSDKTMRVIKEKENYNGLLVDKETTIKRSYEGTLISENSYSKKTP 403 + P+V P Q + +EN + + + +S T +K+T Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE----PQSQTNTTADTEQPAKETS 1176 Query: 404 LNP 406 N Sbjct: 1177 SNV 1179
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 859 bits (2219), Expect = 0.0 Identities = 512/522 (98%), Positives = 515/522 (98%), Gaps = 1/522 (0%) Query: 1 MEQAFFKKIVNCFCLGYLFLSSVIEAAP-DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 59 M QAFFKKIV CFCLGYLFLSS IEA DIKNFNRGRVKVVNKKIAYLGDEKPITIWTS Sbjct: 1 MGQAFFKKIVGCFCLGYLFLSSAIEAVALDIKNFNRGRVKVVNKKIAYLGDEKPITIWTS 60 Query: 60 LDNVTVIQLEKDETISYITTGFNKGWNIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 119 LDNVTVIQLEKDETISYITTGFNKGW+IVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR Sbjct: 61 LDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTR 120 Query: 120 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 179 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL Sbjct: 121 DYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANL 180 Query: 180 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 239 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA Sbjct: 181 ENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA 240 Query: 240 EETIKQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 299 EE ++QRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD Sbjct: 241 EEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKD 300 Query: 300 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 359 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE Sbjct: 301 NFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNE 360 Query: 360 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 419 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF Sbjct: 361 QIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIF 420 Query: 420 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 479 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK Sbjct: 421 DDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK 480 Query: 480 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 521 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK Sbjct: 481 DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK 522
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 119 bits (300), Expect = 3e-35 Identities = 43/205 (20%), Positives = 73/205 (35%), Gaps = 10/205 (4%) Query: 27 KLNKANRTFKRAFYL---SMVLNIAAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSD 83 KL A R+ K A+ + + L A V ++ + PLK + +V +DR TGE I + Sbjct: 24 KLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLH 83 Query: 84 A-RQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQ 142 I EAV + +V G+ + + D +M Q + R + + Q Sbjct: 84 GDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDNPQ 143 Query: 143 FVDKVRA-EAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFA 201 + A + I + +F +T T TI Y Sbjct: 144 SPQNILANRTDVFVEI-KRVSFLGGNVAQVYFTKESVTGSNS----TKTDAVATIKYKVD 198 Query: 202 RGNSSQENLIINPFGFKVFDIQITD 226 S + + NP G++V + Sbjct: 199 GTPSKEVDRFKNPLGYQVESYRADV 223
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 32.8 bits (74), Expect = 0.002 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 13/116 (11%) Query: 24 AINTALLPSEYKKLVALGFKKLYQRHDDKEVTEEEKKFATNALREKLRNDRARAEQIQKN 83 A+N AL+ +Y++ L KKL D + EE+KK L ++ EQ QK Sbjct: 112 AVNFALMTRDYQEF--LKTKKLIVDAPDPKELEEQKK--------ALEKEKEAKEQAQK- 160 Query: 84 IEAFEKKNNSSIQKKATKHKGLQELNETNANPLNGNPNSNSSTETKSNKDDNFDEM 139 A + K +++A L+ L +NP N + N N S K +++ D+M Sbjct: 161 --AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQM 214
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 33.7 bits (77), Expect = 0.004 Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 18/88 (20%) Query: 19 EVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSI-------FILFVT 71 + K K+ EL+ +G+ +D F+ SI F + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMK--VLYPYD--------TTPFVQLSIHEVVKTLFEAIML 350 Query: 72 VVLSVILF-QAYEPVLIVAIVIVLVALG 98 V L + LF Q LI I + +V LG Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLG 378
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.7 bits (67), Expect = 0.006 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 87 LQSYSVMLFFNLLLLIDILGFLPFSIYHHFMASLIFSALFCGSLFLSSPLLGMIALVALS 146 L Y F L+L+ +LPFS S + + +L PLL + AL+A++ Sbjct: 45 LSDYYFEHFSKLMLIPAEQSYLPFSQ----ALSYVVDNVLLEFFYLCFPLLTVAALMAIA 100 Query: 147 SSLL 150 S ++ Sbjct: 101 SHVV 104
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 50.0 bits (119), Expect = 3e-09 Identities = 24/57 (42%), Positives = 28/57 (49%) Query: 83 APKPTLAGPQKPPTPPTPPIPPTPPKPIEKPKPEPKPKPKPEPKKPNHKHKALKKVE 139 P P +P P P P P IEKPKP+PKPKPKP K + +K VE Sbjct: 62 QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVE 118 Score = 45.4 bits (107), Expect = 9e-08 Identities = 38/228 (16%), Positives = 69/228 (30%), Gaps = 53/228 (23%) Query: 84 PKPTLAGPQKPPTPPTPPIPPTPPKPIEKPKPEPKPKPKPEPKKPNHKHKALKKVEKVEE 143 P + P +P P P P P P E P KPKPKP+PK K V+KV+E Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP--------KPVKKVQE 108 Query: 144 KKVVEEKKEEKKIVEQKVEQKKIEEKKPVKKEFDPNQLSFLPKEVAPPRQENNKGLDNQT 203 + + K E + ++ + + + Sbjct: 109 QPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQ------ 162 Query: 204 RRDIDELYGEEFGDLGTAEKDFIRNNLRDIGRITQKYLEYPQVAAYLGQDGTNAVEFYLH 263 YP A L +G V+F + Sbjct: 163 ---------------------------------------YPARAQALRIEGQVKVKFDVT 183 Query: 264 PNGDITDLKIIIGSEYKMLDDNTLKTIQIAYKDYPRPKTKTLIRIRVR 311 P+G + +++I+ M + ++ + +P + ++ I + Sbjct: 184 PDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFK 231 Score = 38.0 bits (88), Expect = 2e-05 Identities = 16/54 (29%), Positives = 23/54 (42%) Query: 74 QDPSKNTQGAPKPTLAGPQKPPTPPTPPIPPTPPKPIEKPKPEPKPKPKPEPKK 127 Q + +P P P P+ PKP KPKP+P K + +PK+ Sbjct: 59 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKR 112 Score = 33.8 bits (77), Expect = 6e-04 Identities = 14/56 (25%), Positives = 23/56 (41%) Query: 74 QDPSKNTQGAPKPTLAGPQKPPTPPTPPIPPTPPKPIEKPKPEPKPKPKPEPKKPN 129 +P + P+P P++ P P P PKP K + +PK +P + Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Score = 30.3 bits (68), Expect = 0.008 Identities = 12/52 (23%), Positives = 16/52 (30%) Query: 75 DPSKNTQGAPKPTLAGPQKPPTPPTPPIPPTPPKPIEKPKPEPKPKPKPEPK 126 +P P + P P P P K E+PK + KP Sbjct: 72 EPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPAS 123
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 100 bits (250), Expect = 1e-30 Identities = 25/77 (32%), Positives = 47/77 (61%) Query: 34 LICDYKNLLDMEIVFSAELGSTQIPLLQILRFEKGSVIDLQKPAGESVDTFVNGRVIGKG 93 + D ++D+ + + ELG T++ + ++LR +GSV+ L AGE +D +NG +I +G Sbjct: 50 AMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQG 109 Query: 94 EVMVFERNLAIRLNEIL 110 EV+V +R+ +I+ Sbjct: 110 EVVVVADKYGVRITDII 126
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 27.8 bits (61), Expect = 0.029 Identities = 28/112 (25%), Positives = 54/112 (48%), Gaps = 11/112 (9%) Query: 27 NQTTELHHKNPYELLVATILSAQCTDARVNKITPKLFEKYPSVKDLAL-----ASLEEVK 81 N+ E+ K E A ++ + T +I + K P+ K+L L A +E+VK Sbjct: 132 NKVVEMSKKAVQETQKAVSVAGEATFLIEKQI---MLNKSPNNKELELTKEEFAKVEQVK 188 Query: 82 EIIKSVSYFNNKSKHLINMAQKVVRDFKGVIPSTQKELMSLDGVGQKTANVV 133 E + + +++ + AQKV+ G+ PS + ++++ V + +NVV Sbjct: 189 ETLMASERALDET---VQEAQKVLNMVNGLNPSNKDQVLAKKDVAKAISNVV 237
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 275 bits (705), Expect = 4e-96 Identities = 113/245 (46%), Positives = 162/245 (66%), Gaps = 2/245 (0%) Query: 1 MRFFIFLILICPLICPLMSADSALPSVNLSLNAPSDPKQLVTTLNVIALLTLLVLAPSLI 60 MR + + + L A + LP + S P + + + +T L P+++ Sbjct: 1 MRRLLSVAPVL-LWLITPLAFAQLPGIT-SQPLPGGGQSWSLPVQTLVFITSLTFIPAIL 58 Query: 61 LVMTSFTRLIVVFSFLRTALGTQQTPPTQILVSLSLILTFFIMEPSLKKAYDTGIKPYMD 120 L+MTSFTR+I+VF LR ALGT PP Q+L+ L+L LTFFIM P + K Y +P+ + Sbjct: 59 LMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSE 118 Query: 121 KKISYTEAFEKSALPFKEFMLKNTREKDLALFFRIRNLPNPKTPDEVSLSVLIPAFMISE 180 +KIS EA EK A P +EFML+ TRE DL LF R+ N + P+ V + +L+PA++ SE Sbjct: 119 EKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSE 178 Query: 181 LKTAFQIGFLLYLPFLVIDMVISSILMAMGMMMLPPVMISLPFKILVFILVDGFNLLTEN 240 LKTAFQIGF +++PFL+ID+VI+S+LMA+GMMM+PP I+LPFK+++F+LVDG+ LL + Sbjct: 179 LKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGS 238 Query: 241 LVASF 245 L SF Sbjct: 239 LAQSF 243
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.007 Identities = 22/86 (25%), Positives = 30/86 (34%), Gaps = 4/86 (4%) Query: 479 KIALKNHSENKNALEVVKEF---KFPYSKPKPNTETTAEMKENDTKEAVEKETKENDTKE 535 K KN + +E K T A+ +TKE ETKE T E Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS-ETKETQTTETKETATVE 1107 Query: 536 TIKKETKEKEIKENDTKEVQETQPKE 561 +K E E + K + PK+ Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQ 1133
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.012 Identities = 12/43 (27%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 71 RIARKNLSKMSEEDFKKMREEVRK--ELEEKTKGLSDEEIKAK 111 ++ K ++ ++MR+ V +E + + LSDEE+K K Sbjct: 4 KLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGK 46
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.9 bits (98), Expect = 7e-06 Identities = 13/49 (26%), Positives = 27/49 (55%) Query: 669 SISGSKLESSNVDLSRSLTNLIVVQRGFQANSKAVTTSDQILNTLLNLK 717 +S + S V+L NL Q+ + AN++ + T++ I + L+N++ Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 39.2 bits (91), Expect = 5e-05 Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 4 SLWSGVNGMQAHQIALDIESNNIANVNTTGFKYSR 38 + + ++G+ A Q AL+ SNNI++ N G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQT 37
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 30.3 bits (68), Expect = 0.009 Identities = 11/33 (33%), Positives = 20/33 (60%) Query: 70 DPEVQILKDLKPDFIVVVAYGKILPKEVLTIAP 102 +P +++L ++KP F+V A P+ + IAP Sbjct: 86 EPNLELLTEMKPSFMVWSAGYGPSPEMLARIAP 118
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 32.9 bits (75), Expect = 0.005 Identities = 22/140 (15%), Positives = 55/140 (39%), Gaps = 13/140 (9%) Query: 342 QTKLNTESFKRIIETLRSKIKENQQKMRDKSKEMSRSFKLESTKNEIKEIRDLIDTANQQ 401 K ++ K L+ + N + K K ++ + K K+ K +L+ Sbjct: 289 YAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYA 348 Query: 402 IANHNEMIK----NIQNQKKICVEQTWKFLVNEFKS---DIQEYNKKHCGLEKGIKKFEN 454 + I+ +N + + ++E K+ ++Q Y KK+ L+K + Sbjct: 349 LKKGLSHIELANYYSENYDTVKIT------LDENKTPSQNVQSYYKKYNKLKKSEEAANE 402 Query: 455 EISEIEDKIKELENEIKELE 474 ++ + E+++ L + + + Sbjct: 403 QLLQNEEELNYLYSVLTNIN 422
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 4e-06 Identities = 26/184 (14%), Positives = 64/184 (34%), Gaps = 18/184 (9%) Query: 37 LAQQKEFEKEVKEKRAQYQSHFKVLEQKEEALKEREKEQKAKFDDAVKQASALALQDERA 96 ++E + + Q+ + QKE L ++ E+ + + ++ R Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 97 KIIEEARKNAFLEQQKGLELLQKELDEKSKQVQELHQKEAEIERLKRENNEAESRLKAEN 156 + + LE + + E EL ++++E+++ E A+ + Sbjct: 238 DDFSSLLHKQAIAKHAVLEQ-ENKYVEAV---NELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 157 EKKLNEKLETERERIEKALHEKNELKFKQQEEQLEMLRNELKNAQRKAELSSQQFQGEVQ 216 + NE L+ R+ + +L + + +A +S +VQ Sbjct: 294 QLFKNEILDKLRQTTDNI---------GLLTLELAKNEERQQASVIRAPVS-----VKVQ 339 Query: 217 ELAI 220 +L + Sbjct: 340 QLKV 343
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 27.9 bits (62), Expect = 0.016 Identities = 19/83 (22%), Positives = 27/83 (32%), Gaps = 10/83 (12%) Query: 69 LGLGSMF-----AGLGVVLAVPTLVGWLFGRSGLTAGERFVVFILGVFSLASLAGMIYCG 123 LG+G A + P G G G+ G + G F+L G + Sbjct: 109 LGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADA 168 Query: 124 YGIITDFSALSAAMWWWSLSKIT 146 + LS W S+ K T Sbjct: 169 L-----YPVLSWLTWPMSVGKWT 186
>PF05844#YopD protein Length = 295 Score = 25.0 bits (54), Expect = 0.035 Identities = 13/65 (20%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 10 SVLKANNPHFDKIFEKHNQLDDDIKTAEQQNASDAEVSHMKKQKLKLKDEIHSMIIEYRE 69 L+A F+ + I++ Q + +V + Q ++E+++ I + + Sbjct: 197 VALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQASAREEEVNATIGQ-SQ 255 Query: 70 KQKSE 74 KQK E Sbjct: 256 KQKVE 260
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.001 Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 34 KKDSASISQNLEKTEIERQNSALSPKQEEANATTTATEESPTKDTAPPLETTAQEKETKQ 93 + + + +QN E + + N + + E + + T+E+ T +T ET EKE K Sbjct: 1056 QDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK---ETATVEKEEKA 1112 Query: 94 ETKQEQEKENEPKQDSVSPTQNNQKA 119 + + E+ +E VSP Q + Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSET 1138 Score = 30.0 bits (67), Expect = 0.007 Identities = 15/87 (17%), Positives = 36/87 (41%), Gaps = 3/87 (3%) Query: 45 EKTEIERQNSALSPKQEEANATTTATEESPTKDTAPPLETTAQEKETKQETKQEQEKENE 104 + E+ + S +SPKQE++ E + D ++ + T +T+Q ++ + Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS- 1176 Query: 105 PKQDSVSPTQNNQKALTTSTMGKKPLE 131 + P + T +++ + P Sbjct: 1177 --SNVEQPVTESTTVNTGNSVVENPEN 1201 Score = 28.9 bits (64), Expect = 0.016 Identities = 26/131 (19%), Positives = 48/131 (36%), Gaps = 29/131 (22%) Query: 33 AKKDSASISQNLEKTEIERQNSALSPKQEEANATTTATEESPTKDT-------------A 79 AK+ +++ N + E+ + E TT T+E+ T + Sbjct: 1069 AKEAKSNVKANTQTNEVAQS------GSETKETQTTETKETATVEKEEKAKVETEKTQEV 1122 Query: 80 PPLETTAQEKETKQETKQEQ---EKENEPKQDSVSPTQNNQK-------ALTTSTMGKKP 129 P + + K+ + ET Q Q +EN+P + P A TS+ ++P Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQP 1182 Query: 130 LEYKVAVSGVN 140 + V+ N Sbjct: 1183 VTESTTVNTGN 1193 Score = 27.7 bits (61), Expect = 0.035 Identities = 24/152 (15%), Positives = 48/152 (31%), Gaps = 13/152 (8%) Query: 44 LEKTEIERQNSALSPKQEEANATTTA---TEESPTKDTAPPLETTAQEKETKQETKQEQE 100 L E+E++N + A + S ++ A E ++ + Sbjct: 980 LYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 101 KENEPKQDSVSPTQNNQKALTTSTMGKKPLEYKVAVSGVNVRAFPSTKGKIIGSLAKDKS 160 KQ+S + +N Q A T+ ++ + A + K + Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAK----------EAKSNVKANTQTNEVAQSG 1089 Query: 161 VKVLEIQNDWAKIEFSNEKKGYVFLKLLKKAE 192 + E Q K + EK+ ++ K E Sbjct: 1090 SETKETQTTETKETATVEKEEKAKVETEKTQE 1121
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 48.8 bits (116), Expect = 5e-10 Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Query: 1 MTSALLGLQIVLAVLIVVVVLLQ--KSSSIGLGAYSGSNDSLFGAKGPASFMAKLTMFLG 58 M ALL + +++A+ +V +++LQ K + +G +G++ +LFG+ G +FM ++T L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 59 LLFVANTIALGYFYNKEYGKSILD 82 LF ++ LG N + Sbjct: 61 TLFFIISLVLGNI-NSNKTNKGSE 83
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Query: 1 MQK-KIFLLEDDYLLSESVKEFLEHLGYEVSCAFNGKEAYERLSVERFNLLLLDVQVPEM 59 M I + +DD + + + L GY+V N + ++ +L++ DV +P+ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 NSLELFRRIKNDFLISTPVIFITALQDNATLKNAFNLGASDYLKKPFDLDELEARIKR 117 N+ +L RIK PV+ ++A T A GA DYL KPFDL EL I R Sbjct: 61 NAFDLLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 430 bits (1108), Expect = e-148 Identities = 164/581 (28%), Positives = 278/581 (47%), Gaps = 81/581 (13%) Query: 10 RLILAIALSFLFIALYSYFFQKPNKTTTQTTKQETTNNHTTTSPNAPNAQHFSVTQTIPQ 69 R +L IAL F+ ++ Q + + + T TTT+ + Q Q Sbjct: 5 RNLLVIALLFVSFMIW----QAWEQDKNPQPQAQQTTQTTTTAAGSAADQG---VPASGQ 57 Query: 70 ENLLSTISFEHARIEIDSLG-RIKQVYLKDKKYLTPKEKGFLEHVG--HLFSSKEN---- 122 L+ ++ + + I++ G ++Q L P L L + Sbjct: 58 GKLI-SVKTDVLDLTINTRGGDVEQALL-------PAYPKELNSTQPFQLLETSPQFIYQ 109 Query: 123 AQPPL--KELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLV--LTQDL 178 AQ L ++ P A+ +PL +N A G NE V D Sbjct: 110 AQSGLTGRDGPDNPANGPRPL-------------YNVEKDAYVLAEGQNELQVPMTYTDA 156 Query: 179 GALTIIKTLTFYDDLHYDLKIAFKSPNN------------------LIPSYVITNGYRPV 220 T KT Y + + + N L P + + Sbjct: 157 AGNTFTKTFVLKRG-DYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFAL 215 Query: 221 ADLDSYTFSGVLLENTDKKIEKIE---DKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDSQ 277 +TF G D+K EK + D + + S +++ + +YF T + Sbjct: 216 -----HTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHN-D 269 Query: 278 GFEALIDSEIGTKNPLGFISLKNEA-----------TLHGYIGPKDYRSLKAISPMLTDV 326 G + +G N + I K++ ++GP+ + A++P L Sbjct: 270 GTNNFYTANLG--NGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLT 327 Query: 327 IEYGLITFFAKGVFVLLDYLYQFVGNWGWAIILLTIIVRLILYPLSYKGMVSMQKLKELA 386 ++YG + F ++ +F LL +++ FVGNWG++II++T IVR I+YPL+ SM K++ L Sbjct: 328 VDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQ 387 Query: 387 PKMKELQEKYKGEPQKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELK 446 PK++ ++E+ + Q++ MM LYK NPLGGC PL++Q+P+F A+Y +L +VEL+ Sbjct: 388 PKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELR 447 Query: 447 SSEWILWIHDLSIMDPYFILPLLMGASMYWHQSVTPNTMTDPMQAKIFKLLPLLFTIFLI 506 + + LWIHDLS DPY+ILP+LMG +M++ Q ++P T+TDPMQ KI +P++FT+F + Sbjct: 448 QAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFL 507 Query: 507 TFPAGLVLYWTTNNILSVLQQLIINKVLENKKRMHAQNKKE 547 FP+GLVLY+ +N+++++QQ +I + LE K+ +H++ KK+ Sbjct: 508 WFPSGLVLYYIVSNLVTIIQQQLIYRGLE-KRGLHSREKKK 547
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.005 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 64 KEESVKETHTKEIHQSAEEKKQKLETETPQEE-KITPKPPKKNLKEES 110 + + + T TKE +E+K K+ETE QE K+T + K + E+ Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET 1138
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 33.3 bits (76), Expect = 0.002 Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 25/134 (18%) Query: 216 LSIVGKPNAGKSSLLNAMLLEERA---LVSDIKGTTR-DTIEE-------------VIEL 258 + ++ +AGK++L ++L A L S KGTTR D + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 259 KGHKVRLIDTAGIRESADRIERLGIEKSLKSLENCDIILGVFDLSKPLEKEDFNLMDTLN 318 + KV +IDT G + + R SL L D + + ++ + L L Sbjct: 66 ENTKVNIIDTPGHMDFLAEVYR-----SLSVL---DGAILLISAKDGVQAQTRILFHALR 117 Query: 319 RAKKPCIVVLNKND 332 + P I +NK D Sbjct: 118 KMGIPTIFFINKID 131
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 220 bits (562), Expect = 6e-77 Identities = 61/147 (41%), Positives = 94/147 (63%) Query: 4 IGIYPGTFDPVTNGHIDIIHRSSELFEKLIIAVAYSSAKNPMFSLKERLKMMQLATKSFK 63 IYPG+FDP+T GH+DII R LF+++ +AV + K PMFS++ERL+ + A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVECVAFEGLLADLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQ 123 N + +FEGL + A++ ++RGLRV+SDFE ELQM NK+L +LET++ + + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 NAFISSSIVRSIIAHKGDASHLVPKEI 150 +F+SSS+V+ + G+ H VP + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHV 148
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 28.8 bits (64), Expect = 0.013 Identities = 14/38 (36%), Positives = 22/38 (57%) Query: 103 NGGHNGLKSIDTLCSNSYYRLRVGISKGIGVIEHVLSK 140 N NG K +T+ SNS Y+ ++ ++KG G + SK Sbjct: 294 NDMRNGYKWSNTMFSNSNYKTQILLTKGDGSGVKLYSK 331
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.4 bits (66), Expect = 0.019 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 3/43 (6%) Query: 246 ILSKHSIDPNSKVFSAPNRLVNAFYDP---KDLPLEKGFNFIE 285 I+++ +D N F P + V FYD K L EKG+ E Sbjct: 113 IITQTIVDKNDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKE 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 4e-04 Identities = 9/51 (17%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 125 TVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLV 175 +Y + ++ Q+D ++ G +G GK + A+ ++ ++ V + Sbjct: 148 EIYRVLARLMQTDLT----LMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 32.8 bits (74), Expect = 0.006 Identities = 72/270 (26%), Positives = 117/270 (43%), Gaps = 33/270 (12%) Query: 545 HLEPGFNPKTL--IESVCSKVLKEFEKVEILDKYGVYQLFKDYYNEVLQDDWFLLSFNDF 602 HLE GFN + + + + + F + + DK L N++++D LS N Sbjct: 527 HLEVGFNKVAIFNLPDLNNLAITSFVRRNLEDKLTTKGLSPQEANKLIKD---FLSSNKE 583 Query: 603 LSAKELRELNPLKDKNKKANYLEEPDFVIQKTYYKSDLIPKNLIKQRFFEKE-AKELEEL 661 L K L + D NY E ++K + DL K+L K+ EKE K+LE Sbjct: 584 LVGKTLNFNKAVADAKNTGNYDE-----VKKA--QKDL-EKSLRKREHLEKEVEKKLESK 635 Query: 662 ENALNEKEADFEEFIEEHSGEEGLFYELKINESVLKKELKNATDLEDKEILKTALELLEA 721 N+ EA + +S ++ +F IN+ + A K I + + LE Sbjct: 636 SGNKNKMEAK----AQANSQKDEIF--ALINKEANRDARAIAYAQNLKGIKRELSDKLEN 689 Query: 722 KNKALKMKNKAHEELE-------LKAFHQYKNLKLGEIKDLIIQDKWLKSLKNALENKIL 774 NK LK +K+ +E + KA K LK G +KDL I +W+ ++N + Sbjct: 690 VNKNLKDFDKSFDEFKNGKNKDFSKAEETLKALK-GSVKDLGINPEWISKVEN-----LN 743 Query: 775 KRINAFTSALNKIISNYSNSLLELDKEVKE 804 +N F + NK S + + +L+ VK+ Sbjct: 744 AALNEFKNGKNKDFSKVTQAKSDLENSVKD 773
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 110 bits (276), Expect = 3e-28 Identities = 71/358 (19%), Positives = 146/358 (40%), Gaps = 25/358 (6%) Query: 97 AKDLAYKSENFILRLEMIPKKANLMILDKEKCVIEA--FRFNDRVAKNDILGALPLN-TY 153 + ++ ++ +N + L + K + + I++ F FN N +G LN Sbjct: 209 SSEICFRLKNNSIDLSLSNLKEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMS 268 Query: 154 EHQERDLDFKGLLDILEKDFLSYQHKE-LEHKKNHIIKRLNIQKERLKEKLEKLEDPKNL 212 + + + + +LE + + + L+ K + + K + R +K + L + Sbjct: 269 KEDYKKIQYDSSSKLLENFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKK 328 Query: 213 QLEAKELQTQASLLLTYQHLINKHESRVVLKDFED---KECAIEIDKSMPLNAFINKKFT 269 + + LL + + K S + L ++ I +D++ + + + Sbjct: 329 CEDKDIFKLYGELLTANIYALKKGLSHIELANYYSENYDTVKITLDENKTPSQNVQSYYK 388 Query: 270 LSKKKKQKSQFLYLEEENLKEKIAFKENQINYVKGA---------KEESVLEMFM---PV 317 K K+ + + +E++ + + + + A K+E + ++ + Sbjct: 389 KYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKKELIETGYIKFKKI 448 Query: 318 KNSKTKRPMSGYEVLYYKDFKIGLGKNQKENIKL-LQDARANDLWMHIRDIPGSHLIVFC 376 SK + + I +GKN +N L L+ A +D+W H ++IPGSH+IV Sbjct: 449 YKSKKSKTSKPMHFISKDGIDIYVGKNNIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKN 508 Query: 377 QKNAPKDEVIMELAKMLIKMQKDVFNS-YEIDYTQRKFVKIIKGAN---VIYSKYRTI 430 + P + ++E A + K +S +DYT+ K VK GA VIYS +TI Sbjct: 509 IMDIP-ESTLLEAANLAAYYSKSQNSSNVPVDYTEVKNVKKPNGAKPGMVIYSTNQTI 565 Score = 34.5 bits (79), Expect = 9e-04 Identities = 21/92 (22%), Positives = 48/92 (52%), Gaps = 5/92 (5%) Query: 46 NAPYIGLSKKPLESVLKNTLALDFCLNKFTKNAKILQANIIDNDRI--LEITGAKDLAYK 103 N P I L+ + +K + L K+ NAKI+ + I+ DRI ++ +L + Sbjct: 55 NYPRIHLTDLTKPNPIKAPMFCMV-LRKYISNAKIVDIHQINQDRIVVIDFESTDELGFN 113 Query: 104 SENFILRLEMIPKKANLMILDK-EKCVIEAFR 134 S + L +E++ + +N+ ++ K + ++++ + Sbjct: 114 SI-YSLIIEIMGRHSNMTLIRKRDNIIMDSIK 144
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.8 bits (59), Expect = 0.014 Identities = 12/73 (16%), Positives = 28/73 (38%), Gaps = 7/73 (9%) Query: 23 ISKQELEHPITEPIYTEALIDTYTFDLSSQQTIRDIYKAMYRNNALIRDAYAKIDSLEKR 82 + +E I ++ L + Y + D K+ +++ L + I+ K+ Sbjct: 266 LMSKEDYKKIQYDSSSKLLENFYY-----AKDKSDRLKS--KSSDLQKIVMNNINRCTKK 318 Query: 83 IRKLEQQLKQAKK 95 + L LK+ + Sbjct: 319 DKILNNTLKKCED 331
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 93.0 bits (231), Expect = 4e-24 Identities = 36/213 (16%), Positives = 71/213 (33%), Gaps = 13/213 (6%) Query: 144 FEEVRD-ASVIYHLEKKLGDYIFYVACFFFGTTVLLVILLIVLLPLKQKEPYLVQFSNNK 202 FEE ++ + VA V+ + L PLK EPY++ N Sbjct: 14 FEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNT 73 Query: 203 ENFALVQ--KADSTITANKALIRSLVGAYVLNRESITHIEQHEKIRQNTIKEQSSNEVWY 260 ++ D+TIT ++A+ + + YV RE + + + + S+ Sbjct: 74 GEASIAAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAR--EEYFDAVMVMSARPEQD 131 Query: 261 EFEKLIA-----YHDSIYTNPLLIRKVKIANI-YLDKDLAYIDIEVGLYHSGELESLKRY 314 + + +I N V+I + +L ++A + +G + Sbjct: 132 RWSRFYKTDNPQSPQNILAN-RTDVFVEIKRVSFLGGNVAQVYFTKESV-TGSNSTKTDA 189 Query: 315 KVVMSFEFKKQEINFDSMSLNPTGFIVTGYDVT 347 + ++ NP G+ V Y Sbjct: 190 VATIKYKVDGTPSKEVDRFKNPLGYQVESYRAD 222
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 132 bits (333), Expect = 3e-40 Identities = 37/202 (18%), Positives = 72/202 (35%), Gaps = 4/202 (1%) Query: 40 QSVFRLERNRLKIAYKLLGFMSFIALVLAIVLISILPLQKTEHHF--VDFLNQDKHYAII 97 + K+A+ + G +A + + ++ PL+ E + VD + A Sbjct: 22 RDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAK 81 Query: 98 QRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQN 157 D +I+ +EA+ + + YV RE + ++ V + S+ R+ KT N Sbjct: 82 LHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDN 141 Query: 158 SIYAQSHLEREVHI-VNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTP 216 Q+ L + V I +A V + + + + + Y D Sbjct: 142 PQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNST-KTDAVATIKYKVDGT 200 Query: 217 DFDYASMPKNPTGFKITRYSIT 238 KNP G+++ Y Sbjct: 201 PSKEVDRFKNPLGYQVESYRAD 222
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 31.3 bits (70), Expect = 0.005 Identities = 23/80 (28%), Positives = 41/80 (51%), Gaps = 13/80 (16%) Query: 182 NNKPLKEEKEEIKEKEEETITIGDSTNAMKIVKKDIQKGYRALKSSQRKWYCLGICSKKS 241 N + ++EEK++I + + + NA+K + + + Y ++ + K+S Sbjct: 364 NKEKIREEKQKIILDQAKALETQYVHNALK--RNPVPRNYNYYQAPE----------KRS 411 Query: 242 KLSLMPEEIFNDKQFTYFKF 261 K +MP EIF+D FTYF F Sbjct: 412 K-HIMPSEIFDDGTFTYFGF 430
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 89.1 bits (221), Expect = 5e-22 Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 19/181 (10%) Query: 6 VLITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYG 65 L+TG G G ++++ LL G++V G+ + + S E L F H Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFHKI 59 Query: 66 DMTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLE 125 D+ D + L A+ ++ + V+ S E P A+++ G L ILE R ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 126 KKTRFYQASTSELYGEVLETPQNENTPF-------NPRSPYAVAKMYAFYITKNYREAYN 178 AS+S +YG N PF +P S YA K + Y Y Sbjct: 120 ---HLLYASSSSVYGL------NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 179 L 179 L Sbjct: 171 L 171
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 49.4 bits (118), Expect = 6e-09 Identities = 52/346 (15%), Positives = 107/346 (30%), Gaps = 54/346 (15%) Query: 5 ILITGAYGMVGQNTALYFKKNKPDV-----------TLLTPKKSELY-----------LL 42 L+TGA G +G + + + V L + EL L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 43 DKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSAYMVENLLMGLYLFSSALDLGVKKA 102 D++ + + R + ++ + AY NL L + ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 103 INLASSCAYPKFAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYVSAEKGVFYKTLV 162 + +SS Y P D ++ + YA K + S G+ L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGLR 177 Query: 163 PCNLYGEFDKFEEKIAHMIPGLIARMHTAKLKNEKEFAMWGDGTARREYLNAKDLARFIS 222 +YG + + P + T + K ++ G +R++ D+A I Sbjct: 178 FFTVYGPWGR---------PDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAII 228 Query: 223 LAYENIASIPS-----------------VMNVGSGVDYSIEEYYKMVAQVLDYKGAFVKD 265 + I + V N+G+ + +Y + + L + Sbjct: 229 RLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNML 288 Query: 266 LSKPVGMQQKLMDISK-QKALKWELEIPLEQGIKEAYEYYLKLLEV 310 +P + + D + + + E ++ G+K +Y +V Sbjct: 289 PLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 150 bits (379), Expect = 2e-49 Identities = 39/140 (27%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 5 EILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHH 64 L ++ +L+ K+H FHW VKG FF +H+ EE+Y+ A+ D +AER++ +G Sbjct: 15 NSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQ 74 Query: 65 PLVTLSEAIKLTRVKEETKTSFHSKDIFKEILEDYKHLEKEFKELSNTAEKEGDKVTVTY 124 P+ T+ E + + + + + ++ + ++ DYK + E K + AE+ D T Sbjct: 75 PVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQDNATADL 133 Query: 125 ADDQLAKLQKSIWMLQAHLA 144 + +++K +WML ++L Sbjct: 134 FVGLIEEVEKQVWMLSSYLG 153
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.015 Identities = 10/71 (14%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 281 IVLQNFLYNAIDAIEALEESEQ-GQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFET 339 +++Q + N I + + Q G++ ++ N + + + G + Sbjct: 258 MLVQTLVENGI--KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------- 308 Query: 340 TKLKGNGLGLA 350 + G GL Sbjct: 309 ---ESTGTGLQ 316
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 364 bits (936), Expect = e-127 Identities = 118/345 (34%), Positives = 191/345 (55%), Gaps = 26/345 (7%) Query: 19 AEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDK-SGSKFTMQSISNMLESVNVKISADDI 77 +I DIAS+ RDNQLIGYGLV+GL GTGD S FT QS+ ML+++ + Sbjct: 28 TSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQS 87 Query: 78 KSKNVAAVMITASLPPFARQGDKIDIQISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQG 137 +KN+AAVM+TA+LPPFA G ++D+ +SS+GDA S++GG L+MT L+ DG IYA+AQG Sbjct: 88 NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQG 147 Query: 138 AIVSGN-----------SNNLLSANIINGATIEREVSYDLFHKNAMVLSLKSPNFKNAIQ 186 A++ SA + NGA IERE+ +VL L++P+F A++ Sbjct: 148 ALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 187 VQNTLNKV----FGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIIDE 242 V + +N +G+ +A D + I + +P + +A ++ + + K++I+E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 243 KSGTIVSGVDIMVHPIVVTSQDITLKITKEP--------LNDSKNTQDLDNNMSLDTAHN 294 ++GTIV G D+ + + V+ +T+++T+ P Q + M++ Sbjct: 268 RTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSK 327 Query: 295 TLSSNGKSITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEM 339 G + +V L IG+ A G+++ILQ +K +GA+ AE+ Sbjct: 328 VAIVEGPDLR--TLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.012 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 7/104 (6%) Query: 224 PSNTTNT--DITQRFYVINEHERAEAIM-HLLDTQAPKKSI-VFTRTKKEADELHQFLAS 279 P+N D+ Y + E E+ +AI+ + + A + + V T + ++++ + L Sbjct: 413 PTNRPMIRKDLPDLVY-MTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTK 471 Query: 280 KNYKSTALHGDMDQRDRRASIMAFKKNDADVLVATDVASRGLDI 323 K L+ + A+I+A A V +AT++A RG DI Sbjct: 472 AGIKHNVLNAKFHANE--AAIVAQAGYPAAVTIATNMAGRGTDI 513
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.5 bits (74), Expect = 0.004 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 30 VAIVGESGSGKSSIANLIMRLNPR----FKPHNGEVLFETTNLLKESEAF 75 + I GESG+GK +A + R F N + L ESE F Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD---LIESELF 209
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 556 bits (1435), Expect = 0.0 Identities = 178/582 (30%), Positives = 295/582 (50%), Gaps = 66/582 (11%) Query: 11 VDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFEGLDSSDNALIL 70 +++ +L +I LI AG A++V ++L+ K DY LF L D I+ Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWA-KTPDYR-----TLFSNLSDQDGGAIV 66 Query: 71 QHLQQNQIPYKVSKDD-TILIPRDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFD 129 L Q IPY+ + I +P DKV+E R+ LA QG+PK VGFE+ D + FG + F Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 130 QNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLS 189 + + RA+EGEL+RTIE+L P+ A VH+A+PK S+FV ++ PSASV + L+P L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 190 PTQILGIKNLIAAAVPKLTTENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENIL 249 QI + +L+++AV L NV +V+++G + + + + ++L QL++ + E+ + Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNT--SGRDLNDAQLKFANDVESRI 244 Query: 250 ENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNN-----VVRSEQNLEEKKE 304 + +I IL+PIVG N V A+V A+ DF+ K+ T+E + PN +RS Q ++ Sbjct: 245 QRRIEAILSPIVGNGN-VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQV 303 Query: 305 GAPKKQVGGVPGVVSN-IGPVQGLKDNKEPEKYEKSQN---------------------- 341 GA GGVPG +SN P P + +QN Sbjct: 304 GAGYP--GGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNE 361 Query: 342 TTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLQKINAL 401 T+NYEV +TI K G + RL+ AVVV+ K L DG + PL+ + +++I L Sbjct: 362 TSNYEVDRTIRHTKMNVGDIERLSVAVVVNYK---TLADG----KPLPLTADQMKQIEDL 414 Query: 402 VKQAIGYNQNRGDDVAVSNFEFNPMAPMIDNATLSEKIMHKTQKILGSFTPLIKYILVFI 461 ++A+G++ RGD + V N F+ + T E + Q + +++LV + Sbjct: 415 TREAMGFSDKRGDTLNVVNSPFSAVDN-----TGGELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 462 VLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNA 521 V +I ++K + P R +E ++ + E + E L+K L+++ +Q Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQ----- 524 Query: 522 TFSEEEVRYEIVLEKIRGTLKERPDEIAMLFKLLIKDEISSD 563 + E++ ++IR E D + L+I+ +S+D Sbjct: 525 -----RLGAEVMSQRIR----EMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 350 bits (900), Expect = e-122 Identities = 121/338 (35%), Positives = 208/338 (61%), Gaps = 4/338 (1%) Query: 8 KQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAV 67 K+ + L+ +K AILL+ +G + + ++ ++L + I ++ +I +L ++ V Sbjct: 7 KEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNV 66 Query: 68 LEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAKKVMDKLTKSLQTQKNFAYLGKIKP 127 L EF + + ++I GG++YARELL ++LG+++A +++ L +LQ+ + F ++ + P Sbjct: 67 LLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQS-RPFEFVRRADP 125 Query: 128 QQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRV 187 + +FI EHPQTIALIL++++ A+ LS P E++ ++ R+A + SP+VV+ V Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185 Query: 188 STVLENKLESLTSYK-IEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMF 246 VLE KL SL+S GG+ V EI N +K+ K + +E D +LA IK+ MF Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMF 245 Query: 247 TFEDISKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFVEEMQYLG 306 FEDI LD+ +I+ +L+ D ++L+ ALK+ + +K NMS RAA E+M++LG Sbjct: 246 VFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLG 305 Query: 307 AVKIKDVDVAQRKIIEIVQSLQEKG--VIQTGEEEDVI 342 + KDV+ +Q+KI+ +++ L+E+G VI G EEDV+ Sbjct: 306 PTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343 Score = 30.2 bits (68), Expect = 0.010 Identities = 20/102 (19%), Positives = 41/102 (40%), Gaps = 3/102 (2%) Query: 4 KLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQI 63 + P + + IA++L + IL L + T ++++I ++ T ++ Sbjct: 122 RADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEV 181 Query: 64 GAA---VLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEA 102 VLE+ A S Y + GG++ E++ E Sbjct: 182 VREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEK 223
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 37.5 bits (86), Expect = 3e-05 Identities = 45/207 (21%), Positives = 91/207 (43%), Gaps = 14/207 (6%) Query: 49 PLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEES-KALIENAKNDGYKIGFKEG 107 E I + + L L +LQMQ A E+ +A I + G+K G++EG Sbjct: 19 QAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQ---AHEQGYQAGIAEGRQQGHKQGYQEG 75 Query: 108 EEKMRNELTHSVNEEKNQLLHAITALDEKMKKSQDHLMALE----KELSAIAIDIAKEVI 163 + L + E K+Q + + + + Q L AL+ L +A++ A++VI Sbjct: 76 ---LAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVI 132 Query: 164 LKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNERLQNASKI---KLESNE 220 + ++ + + + L + L + L+V+P D +++ L + +L + Sbjct: 133 GQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDP 192 Query: 221 AISKGGVMITSSNGSLDGNLMERFKTL 247 + GG +++ G LD ++ R++ L Sbjct: 193 TLHPGGCKVSADEGDLDASVATRWQEL 219
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 114 bits (287), Expect = 7e-29 Identities = 53/162 (32%), Positives = 88/162 (54%), Gaps = 7/162 (4%) Query: 9 NIRNFSIIAHIDHGKSTLADCLIFECNAIS---NREMKSQVMDTMDIEKERGITIKAQSV 65 I N ++AH+D GK+TL + L++ AI+ + + + D +E++RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 66 RLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANVYIAL 125 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 126 DNHLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSGANEVS 167 + + INKID ++ V QDI++ + + +V Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVE 159 Score = 82.2 bits (203), Expect = 2e-18 Identities = 50/215 (23%), Positives = 90/215 (41%), Gaps = 17/215 (7%) Query: 167 SAKAKLGIKDLLEKIITTIPAPSGDPNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQ 226 SAK +GI +L+E I + + + L ++ + LA +R+ G ++ Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 227 EILVMGTGKRHGVLGLYYPNPLKKIPTKSLECGEIGIV---SLGLKSVTDIAVGDTLTDA 283 + + K + +Y + GEI I+ L L SV +GDT Sbjct: 280 SVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLL- 333 Query: 284 KNPTPKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFG 343 P + IE P + + P + + E L +ALL++ +D L + +S+ Sbjct: 334 --PQRERIEN---PLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---E 385 Query: 344 FRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVY 378 + FLG + MEV L+ ++ + + PTV+Y Sbjct: 386 IILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Score = 31.0 bits (70), Expect = 0.015 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 405 IKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDK 464 + EP++ I P E+L + L + V+L+ +P+ I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 465 LKSCTKGYASFDYEP 479 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.008 Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 3 NGYYAATGAMATQFNRLDLTSNNLANLNTNGFKRDDAITG 42 + A + L+ SNN+++ N G+ R I Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA 41
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 58/315 (18%), Positives = 104/315 (33%), Gaps = 67/315 (21%) Query: 35 APYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMA 94 P A +F T + +AF++ G+ +GKL D+ G K +++ II+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLLLFGIIINC 90 Query: 95 LGSFLLALLPTKEIVGEWAFLFLLLARLLQGFSVGGE------YGVVATYLSELGKNGKK 148 GS + VG F L++AR +QG G VVA Y+ + + Sbjct: 91 FGSVIGF-------VGHSFFSLLIMARFIQG--AGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 149 GFYGSFQYVTLVGGQLLAIFSLFIVENIYTHEQISAFAWRYLFALGGILALLSLFLRNIM 208 G GS + +G + I I+ W YL + I + FL ++ Sbjct: 142 GLIGS---IVAMGEGVGPAIGGMIAHYIH---------WSYLLLIPMITIITVPFLMKLL 189 Query: 209 EETMDSQTTSKTTIREETQRGSLKELLNHKKALM-------IVFGLTMGGSLCFYTFTVY 261 + + +K + K ++ + T + Sbjct: 190 K-----------------KEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 262 LKIFLTNSSSFSPK-------ESSFIMLLALSYFIFLQPLCG---MLADKIKRTQMLMVF 311 IF+ + + ++ M+ L I + G M+ +K L Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 312 AITGLIVTPVVFYGI 326 I +I+ P I Sbjct: 293 EIGSVIIFPGTMSVI 307
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.4 bits (86), Expect = 3e-04 Identities = 32/144 (22%), Positives = 45/144 (31%), Gaps = 19/144 (13%) Query: 259 NPTNPTLKELKQETKEREPTPTKETLT-----------------PTTPKPATLKPIMPTP 301 N + + ETKE + T TKET T P + K Sbjct: 1079 NTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET 1138 Query: 302 IMPASAPIIENDNKTENQKTPNPPKKEESPQENPQKENQKENIEEKENLKEEEKEIQDAP 361 + P + P END T N K P + E P KE N+E+ Sbjct: 1139 VQPQAEPAREND-PTVNIKEPQSQTNTTADTEQPAKETSS-NVEQPVTESTTVNTGNSVV 1196 Query: 362 SFSPLTPTSAKKPVMVKELSENKE 385 T + +P + E S + Sbjct: 1197 ENPENTTPATTQPTVNSESSNKPK 1220
>FLAGELLIN#Flagellin signature. Length = 507 Score = 244 bits (624), Expect = 6e-77 Identities = 126/518 (24%), Positives = 209/518 (40%), Gaps = 22/518 (4%) Query: 2 AFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSL 61 A +NTN ++ +Q++L +++ERLSSGLRIN A DDA+G +A+ S L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQ 121 QA N NDG+ I Q + A++E L V+ + QA + K+IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 GLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRI-ATGALI 180 +D + N T +NG +LS + QVGA ++I + +G G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 181 TASGDISLTFKQVDGVNDVTLESVKVSSSAGTGIGVLAEVINKNSNRTGVKAYASVITTS 240 GD+ +FK V G + + + K +G V ++ V A +TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 241 DVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQKGRLNLR 300 D N + K A A+ + + + + Sbjct: 240 DAE-----------NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 301 SIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINV------VS 354 + G K + NG V S + +N + Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 355 ASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSL---G 411 ++S L ++ TVN + T N + + +G + S Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 412 SGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRD 471 + + +SA+ +D VRS LG++QN+ S + N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 472 VDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLL 509 D+A E +N +K IL Q+G+ ++QAN V QN+L LL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.008 Identities = 13/95 (13%), Positives = 26/95 (27%), Gaps = 20/95 (21%) Query: 60 ILENDDEINLKKIAYIEFSKLAECVRPSGFYNQKAKRLIDLSGNILKDFQSFENFKQEVT 119 L + + +A+ E + VR + +KA E+ Sbjct: 458 ALRSAPALA-GCVAFDELREQPVAVRAFPW--RKAPGP-------------LEDADVLRL 501 Query: 120 REWLLDQKGIGKESADAILCYVCAKEVMVVDKYSY 154 +++ G G+ SA + D Sbjct: 502 ADYVETTYGTGEASAQTTEQAINV----AADMNRV 532
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.023 Identities = 16/113 (14%), Positives = 41/113 (36%), Gaps = 16/113 (14%) Query: 203 LARMIALQKKLEQIKTDIKRVTKLYDEGLTTIDDL-----QSLKAQGNLSEY--DILDIQ 255 LAR+ + K+ + + L + + + ++A L Y + I+ Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279 Query: 256 FALEQNRLTLEYLTNLSVKNLKKTTIDAPNLQLRERQD-LVSLREQISALKYQ 307 + + + +T K +D +LR+ D + L +++ + + Sbjct: 280 SEILSAKEEYQLVTQ----LFKNEILD----KLRQTTDNIGLLTLELAKNEER 324
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.0 bits (122), Expect = 1e-09 Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 27 NVQAVQDSKLTLDSTGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQ 86 + ++ IV I V EG V+KGDVLL L +A + T+ L+ A+ + Sbjct: 95 RSKEIKPI-----ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE 149 Query: 87 YQRYSKTGGAVDKNTLESYEFN 108 RY +++ N L + Sbjct: 150 QTRYQILSRSIELNKLPELKLP 171 Score = 29.4 bits (66), Expect = 0.012 Identities = 21/152 (13%), Positives = 47/152 (30%), Gaps = 25/152 (16%) Query: 70 QAQSDSTEQQLIFAKKQYQR--YSKTGGAVDKNTLESYEFNYRRLESDYAYSIAVLNKTI 127 +++ S +++ + ++ K D + + E ++ Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDN--IGLLTLELAKNEER-------QQASV 329 Query: 128 LRAPFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIE--FDSKYINAVKVG------ 179 +RAP + + GV L+ +V L + +K I + VG Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 180 -DTYTYSIDGDSNQHEAKITKIYP--TVDENT 208 + + Y+ G K+ I D+ Sbjct: 390 VEAFPYTRYGYL---VGKVKNINLDAIEDQRL 418
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 894 bits (2312), Expect = 0.0 Identities = 287/1038 (27%), Positives = 519/1038 (50%), Gaps = 41/1038 (3%) Query: 1 MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK 60 M I RPI + A+ ++ G + +L VA +P I P V V+ YPGA A+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTDKIEEAVMGIDGIKKVTSTSSKNVSIVV-IEFELEKPNEEALNDVVNKISSVR-FDDS 118 VT IE+ + GID + ++STS S+ + + F+ + A V NK+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 NIKKPSINKFDTDSQAIISLFVSSSSVPAT--TLNDYAKNTIKPMLQKINGVGGVQLNGF 176 +++ I+ + S ++ S + T ++DY + +K L ++NGVG VQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 177 RERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNS------QRELSILINAN 230 + +RI+ D L+NKY LT D+ + LK +N +I G++ + Q SI+ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 231 SYSVADVEKIQV-----GNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANE 285 + + K+ + G+ VRL D+A++E+G E N A KP L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 286 IEIVDRVYEALKHIQAISP-NYEIRPFLDTTGYIRTSIEDVKFDLVLGAILAVLVVFAFL 344 ++ + L +Q P ++ DTT +++ SI +V L +L LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 345 RNGTITLVSAISIPISIMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHK- 403 +N TL+ I++P+ ++GTFA++ G+S+N LTM + LAIG+++DDAIVV+EN+ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 404 KLEMGMDKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIA 463 +E + ++A+ + + +I ALV I+ +L +VF+P+ G G ++ F IT+ A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 464 LSYVVVVTIIPMVSSVVVNPKHS-------RFYVWSEPFFKALESYYTRLLQWVLNHKLI 516 LS +V + + P + + ++ P + F+ W F ++YT + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 517 IFIAVVLVFVGSLFVASKIGMEFMLKEDRGRFLVWLKAKPGVSIDY----MTQKSKIFQK 572 + L+ G + + ++ F+ +ED+G FL ++ G + + + Q + + K Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 573 AIEKHAEVEFTTLQVGY-GTTQNPFKAKIFVQLKPLKERKKEHELGQFELMSALKKELKS 631 + + E FT + G QN FV LKP +ER E ++ K EL Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNA--GMAFVSLKPWEERNG-DENSAEAVIHRAKMELGK 656 Query: 632 MPESKGLESINLSEVSLIGGGGDSSPFQTFVFSHSQEAVDKSVANLKKFLLESPELKGKV 691 + + + N+ + G ++ F + + D + L + + + Sbjct: 657 IRDGF-VIPFNMPAIV---ELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 692 ESYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQASVFKQDGKEYDMI 751 S + E Q +L++ ++ A GVS I +S+A G + + F G+ + Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG-TYVNDFIDRGRVKKLY 771 Query: 752 IRVPDNKRVSVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPA 811 ++ R+ ED+ +L VR+ +++ A + RYN S+ + + A Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 812 -GISLGEILTQVSKNTKEWLVEGANYRFTGEADNAKETNGEFLIAIATAFVLIYMILAAL 870 G S G+ + + +N L G Y +TG + + + + +A +FV++++ LAAL Sbjct: 832 PGTSSGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 871 YESILEPFIIMVTMPLSFSGAFFALSLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANE 930 YES P +M+ +PL G A +L +Q ++ M+GL+ IG+ KNA L+++ A + Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 931 -ERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSGGL 989 K+G + EA L A + RLRPILMT++A + G+LPLA+++G G+ ++ +GI + GG+ Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 990 MISMVLSLLIVPVFYRLL 1007 + + +L++ VPVF+ ++ Sbjct: 1011 VSATLLAIFFVPVFFVVI 1028
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 278 bits (712), Expect = 1e-77 Identities = 104/394 (26%), Positives = 182/394 (46%), Gaps = 14/394 (3%) Query: 2797 NAVNWLNALFVAKGGNPLFAPYYLQDTPTEHIVTLMKDVSSALGMLSKPNLKNNSTDVLQ 2856 + L L + + +A + T I + ++ L ++ K + L Sbjct: 907 QGRDLLQTLLI-DSHDAGYARTMIDATSANEITKQLNTATTTLNNIASLEHKTSGLQTLS 965 Query: 2857 LNTYTQQMGRLAKLSNFASFDSTDFSERLSSLKNQRFTDAIPNAMDVILKYSQRDKLKNN 2916 L+ RL LS + F++RL +LK+QRF + +A +V+ +++ + + N Sbjct: 966 LSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFAS-LESAAEVLYQFAPKYEKPTN 1024 Query: 2917 LWATGVGGVSFVENGTGTLYGVNVGYDRFIKG---VIVGGYAAYGYSGFYER--ITSSKS 2971 +WA +GG S G +LYG + G D ++ G IVGG+ +YGYS F + +S + Sbjct: 1025 VWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSNQANSLNSGA 1084 Query: 2972 DNVDVGLYARAFIKKSELTFSVNEAWGANKTQISSSDALLSMINQSYQYNTWTTNARVNY 3031 +N + G+Y+R F + E F A G++++ ++ ALL +NQSY Y ++ R +Y Sbjct: 1085 NNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLAYSAATRASY 1144 Query: 3032 GYDFMFKNKSIILKPQIGLRYYYIGMSGLEGVMDNALYNQFKANADPSKKSVLTIDLALE 3091 GYDF F +++LKP +G+ Y ++G + + + S + + +E Sbjct: 1145 GYDFAFFRNALVLKPSVGVSYNHLGSTNFKS----NSNQKVALKNGASSQHLFNASANVE 1200 Query: 3092 NRHYFSTNSYFYAIGGFGRDLLVNSMGDKLVRFIGNNTLSYRKGELYNTFASITTGGEVR 3151 R+Y+ SYFY G ++ N V + R NT A + GGE++ Sbjct: 1201 ARYYYGDTSYFYMNAGVLQEFA-NFGSSNAVSLNTFKVNATRNP--LNTHARVMMGGELK 1257 Query: 3152 LFKSFYANAGVGARFGLDYKMINITGNIGMRLAF 3185 L K + N G L + + N+GMR +F Sbjct: 1258 LAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 31.2 bits (70), Expect = 6e-04 Identities = 16/33 (48%), Positives = 20/33 (60%) Query: 16 KRKKLLTELAELEAEIKVSSERKSSFNISLSPS 48 R KL ELAEL AE+K+ S ++ N LS S Sbjct: 149 ARSKLREELAELTAELKIYSVIQAEINKHLSSS 181
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.5 bits (131), Expect = 2e-10 Identities = 24/110 (21%), Positives = 44/110 (40%), Gaps = 6/110 (5%) Query: 194 ILIAEDSLSALKTLEKIVQTLELRYLAFPNGRELLDYLYEKEHYQQVGVVITDLEMPVIS 253 IL+A+D + L + + N L ++ +V+TD+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA----GDGDLVVTDVVMPDEN 61 Query: 254 GFEVLKTIKADSRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILE 303 F++L IK LPV++ S+ ++ A A ++ K L Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 120 bits (302), Expect = 6e-36 Identities = 51/119 (42%), Positives = 75/119 (63%), Gaps = 2/119 (1%) Query: 1 MRNIEARK-EKGDKEAKLAFEMCAYHIKKYIGAYMVALGRVDAIIFTGGMGENYPALRES 59 R++E + GDK A+LA + AY +KK IG+Y A+G VD I+FT G+GEN P +RE Sbjct: 283 FRDLEDAAFKNGDKRAQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREF 342 Query: 60 VCEGLENLGIALHKITNDNPGNGLVDLSQPNTKIQVLLIPTDEELEIALQAKEIIEKLK 118 + +GLE LG L K N G +S ++K+ V+++PT+EE IA ++I+E LK Sbjct: 343 ILDGLEFLGFKLDKEKNKVRGEE-AIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 360 bits (926), Expect = e-126 Identities = 142/282 (50%), Positives = 198/282 (70%), Gaps = 6/282 (2%) Query: 1 MEILVLNLGSSSIKFKLFDMKENKPLASGLAEKIGEEIGQLKIKSHLHHNDQELKEKLVI 60 M+ILV+N GSSS+K++L + K+ LA GLAE+IG L N +++K K + Sbjct: 1 MKILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHN----ANGEKIKIKKDM 56 Query: 61 KDHASGLLMIRESLT--KMGIIKDFNQIDAIGHRVVQGGDKFHAPVLVNELVMQEIGKLS 118 KDH + ++ ++L G+IKD ++IDA+GHRVV GG+ F + VL+ + V++ I Sbjct: 57 KDHKDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCI 116 Query: 119 VLAPLHNPANLAGIEFVQKAHPHIPQIAVFDTAFHSSMPDFAYMYALPYELYEKYQIRRY 178 LAPLHNPAN+ GI+ + P +P +AVFDTAFH +MPD+AY+Y +PYE Y KY+IR+Y Sbjct: 117 ELAPLHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKY 176 Query: 179 GFHGTSHHYVAKEAAKYLRIPYEKFNAISLHLGNGASVAAIRDGKSVDTSMGLTPLEGLI 238 GFHGTSH YV++ AA+ L P E I+ HLGNG+S+AA+++GKS+DTSMG TPLEGL Sbjct: 177 GFHGTSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLA 236 Query: 239 MGTRCGDIDPTVVEYIAQCANKSLEEVMKILNYESGLKGICG 280 MGTR G IDP+++ Y+ + N S EEV+ ILN +SG+ GI G Sbjct: 237 MGTRSGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISG 278
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.4 bits (107), Expect = 5e-07 Identities = 42/231 (18%), Positives = 76/231 (32%), Gaps = 10/231 (4%) Query: 280 KRDKTLSKKKPEKTQTKTQTTAPSIAPENAPKIPLKTPPLMPLIGANPPPNDNAPTLLEK 339 KR++T+ T Q PS+ N + P+ P A P E Sbjct: 987 KRNQTVDTTNIT-TPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS---------ET 1036 Query: 340 EEKTKEVSENKEKTKESTNSAQNAQNTQASDKTSENKSVTPKETIKHFTQQLKQEIQEYK 399 E E S+ + KT E Q + E KS T + Q E +E + Sbjct: 1037 TETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 400 PPMSKISMDLFPKELGKVEVIIQKVGKNLKVSVISHNNSLQTFLDNQQDLKNSLNALGFE 459 +K + + +E KVE + + V +T + + + + + Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 460 GVDLSFSQDSSKEQPKEQLRELFKEQESSPLKENALKSYQENTDHENKETS 510 + + EQP ++ ++ + N S EN ++ T+ Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Score = 41.2 bits (96), Expect = 1e-05 Identities = 58/278 (20%), Positives = 101/278 (36%), Gaps = 26/278 (9%) Query: 21 KNEVKDTKNAP----KSASKDFSKILNQKISKDKTAPKENPLKATPKGTK----ENAKAL 72 +N+ DT N A N++I++ AP P ATP T EN+K Sbjct: 988 RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 73 EKTPTPHHQHAQNLAKDQQAPTLKDLLNHKKTTASHEAQHETHEMHETNPKTPNETLNKN 132 KT + Q A + + N K T ++E E ET ET Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 133 EKKPNGVVSN------AHQSNLTNKNPLTPTNHANHAIKKPTAPTHNAKDPKTLKDIQ-T 185 +++ V + S ++ K + T + PT N K+P++ + Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 186 LSQKHDLNASNIQVVAPLEKKETSLKAGDQIALKTTQTPINHTLAKNDAKNTANLSSVLQ 245 Q +SN++ + T++ G+ + + P N T A + S+ + Sbjct: 1168 TEQPAKETSSNVE---QPVTESTTVNTGNSV----VENPENTTPATTQPTVNSESSNKPK 1220 Query: 246 SLEKK----ESHHKEHATPPSNEKKTPPLKEALQMNAI 279 + ++ H+ E AT SN++ T L + N Sbjct: 1221 NRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 35.3 bits (81), Expect = 7e-04 Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 2 NDTLLNAYSGIKTHQFGIDSLSNNIANVNTLGY 34 + + NA SG+ Q +++ SNNI++ N GY Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGY 33 Score = 33.0 bits (75), Expect = 0.003 Identities = 10/48 (20%), Positives = 20/48 (41%) Query: 557 IRHKYLETSNVNAGNALTNLILMQRGYSMNARAFGAGDDMIKEAISLK 604 + ++ S VN NL Q+ Y NA+ + + I+++ Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 810 bits (2094), Expect = 0.0 Identities = 223/1062 (20%), Positives = 447/1062 (42%), Gaps = 73/1062 (6%) Query: 5 IIDLSVKNKLLTTLITLLIFLASLWAIKSVRLDALPDLSPAQVVVQITYPNQSPKIVQEQ 64 + + ++ + ++ +++ +A AI + + P ++P V V YP + VQ+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTYPLVSTFMSIANIDTVRGIS-SYESGLIYIIFKDGVNLYWARDRVLEQLNRVSN-LPK 122 VT + I N+ + S S S I + F+ G + A+ +V +L + LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 123 DAKV-EIGSDSTSIGWAYQYALSSGSKNLS--DLKVLQDFYYRYALLGVDGVSEVASVGG 179 + + I + +S + S + + D+ + L ++GV +V G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 FVKDYEVTLQNDSLIRYNLSLEQVANAIKNSNNDTGGGVI------LENGFEKIIRSHGY 233 + L D L +Y L+ V N +K N+ G + I + Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 IQSLNDLEEIVVK-KEGAIPLKIKDIASVRLVPKPRRGAANLNGDKEVVGGIVMVRYHAD 292 ++ + ++ ++ +++KD+A V L + A +NG K G + + A+ Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING-KPAAGLGIKLATGAN 298 Query: 293 TYKVLKAIKEKIATLQASNP-DVKITSVYDRSELIEKGIDNLIHTLIEESAIVLVIIAIF 351 KAIK K+A LQ P +K+ YD + ++ I ++ TL E +V +++ +F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 352 LLHFRSALVVIITLPLSVCISFLLMRYFNIEASIMSLGGIAIAIGAMVDAAIVMVENAHK 411 L + R+ L+ I +P+ + +F ++ F + +++ G+ +AIG +VD AIV+VEN + Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 412 HLQHIDTKDNAQRVNAIMQGVKHVGGAIFFALMIIVVSFLPIFALTGQEEKLFAPLAYTK 471 + +D A + + + GA+ M++ F+P+ G ++ + T Sbjct: 419 VMM----EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 472 TFAMLVGALLSITIVPVLMVWLIKGRILEESKNPINAFF----------MKIYGVSLNVV 521 AM + L+++ + P L L+K E +N FF + Y S+ + Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENK-GGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 522 LKFRYAFLIASVLGLGGLYVAYKKLNWEFIPQINEGVIMYMPVTLNGVGID-------TA 574 L +L+ L + G+ V + +L F+P+ ++GV + M G + Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 575 LEYLKKSNSAIKQLDFVKQVFGKVGRANTSTDAAGLGMIETYIELKPKNEWKEKLSYKEV 634 +Y K+ A + F F G+A + A ++ LKP W+E+ + Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSGQAQNAGMA--------FVSLKP---WEERNGDENS 642 Query: 635 RDKL--EKTLQLKGLTNSWTYPIRGRTDMLLTGIRTPLGIKL-------YGNDTDKLQEL 685 + + ++L + + + P + L G T +L + T +L Sbjct: 643 AEAVIHRAKMELGKIRDGFVIPFNMPAIVEL-GTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 686 AILMEQQLKTLKESLSVFAERSNNGYYITLDLNDENLARYGINKNAVLDAIKFALGGATL 745 + Q +L +SV + L+++ E G++ + + I ALGG + Sbjct: 702 LGMAAQHPASL---VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYV 758 Query: 746 TTMIKGVESYPISLRLEDTERNTIEKLKNLYIKTAYNYM-PLRELAHVYYDNSPAVLKSE 804 I + ++ + R E + LY+++A M P ++ L+ Sbjct: 759 NDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERY 818 Query: 805 KGLNVNFIYIVPQNGISSDTYRQLAQKALEKIQLPNGYYYEFSGESQYLEEAFKTLQYIV 864 GL I G SS L + K LP G Y+++G S + +V Sbjct: 819 NGLPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALV 876 Query: 865 PVSVFIIFILIVFALKNLTNSLLCFFTLPFAFLGGLIFMNLMGFNMSVAALVGFLALLGV 924 +S ++F+ + ++ + + +P +G L+ L V +VG L +G+ Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 925 ASETAIVMIIYLEDAFQKFIKTPLKEQNSTALKEAIMHGAVLRVRPKLMTFFSILASLIP 984 +++ AI+++ + +D L E+ + EA + +R+RP LMT + + ++P Sbjct: 937 SAKNAILIVEFAKD---------LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLP 987 Query: 985 IMYSHGTGSEIMKSIAAPMLGGMISSVVLTLFIIPTAYFVIK 1026 + S+G GS ++ ++GGM+S+ +L +F +P + VI+ Sbjct: 988 LAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIR 1029 Score = 73.3 bits (180), Expect = 3e-15 Identities = 76/531 (14%), Positives = 194/531 (36%), Gaps = 60/531 (11%) Query: 527 AFLIASVLGLGGLYVAYKKLNWEFIPQINEGVIMYMPVTLNGVGI------DTALEYLKK 580 A+++A +L + G A +L P I + V+ N G DT + +++ Sbjct: 12 AWVLAIILMMAGAL-AILQLPVAQYPTIAPPAVS---VSANYPGADAQTVQDTVTQVIEQ 67 Query: 581 SNSAIKQLDFVKQVFGKVGRANTSTDAAGLGMIETYIEL-----KPKNEWKEKLSYKEVR 635 + + I L ++ ++++D+AG I + + + + KL Sbjct: 68 NMNGIDNLMYM----------SSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQ--LAT 115 Query: 636 DKLEKTLQLKGLTNSWTYPIRGRTDMLLTGIRTPLGIKLYGNDTDKLQ-ELAILMEQQLK 694 L + +Q +G++ + + ++ Q +++ + +K Sbjct: 116 PLLPQEVQQQGISVEKSSSS------------YLMVAGFVSDNPGTTQDDISDYVASNVK 163 Query: 695 TLKESLSVFAERSNNG--YYITLDLNDENLARYGINKNAVLDAIKFA---LGGATLTTMI 749 L+ + G Y + + L+ + L +Y + V++ +K + L Sbjct: 164 DTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTP 223 Query: 750 KGVESYPISLRLEDTERNTIEKLKNLYIKTAYNYMP--LRELAHVYYD-NSPAVLKSEKG 806 + + T E+ + ++ + L+++A V + V+ G Sbjct: 224 ALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING 283 Query: 807 LNVNFIYIVPQNGISSDTYRQLAQKALEKIQ--LPNGYYYE-FSGESQYLEEAFKTLQYI 863 + I G ++ + + L ++Q P G + +++ + + Sbjct: 284 KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKT 343 Query: 864 VPVSVFIIFILIVFALKNLTNSLLCFFTLPFAFLGGLIFMNLMGFNMSVAALVGFLALLG 923 + ++ ++F+++ L+N+ +L+ +P LG + G++++ + G + +G Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 Query: 924 VASETAIVMIIYLEDAFQKFIKTPLKEQNSTALKEAIMHGAVLRVRPKLMTFFSILASLI 983 + + AIV++ +E + + KEA + + A I Sbjct: 404 LLVDDAIVVVENVERVMME---------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFI 454 Query: 984 PIMYSHGTGSEIMKSIAAPMLGGMISSVVLTLFIIPTAYFVIKNARVRKHE 1034 P+ + G+ I + + ++ M SV++ L + P + +H Sbjct: 455 PMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHH 505
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.5 bits (61), Expect = 0.048 Identities = 18/88 (20%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 144 IGSLIGSLAGSHFSFD---TQGMEFVMTAIFIVLFMEQYKRTTNHKN--AWLGIIIAVVC 198 +G IG + + + M ++T F++ +++ R H + + + + +V Sbjct: 154 VGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213 Query: 199 LVLFGTEYFLLIALVLMVLALILFRKQL 226 +LF T Y + L++ VL+ ++F K + Sbjct: 214 FMLFTTSYSISF-LIVSVLSFLIFVKHI 240
>cloacin#Cloacin signature. Length = 551 Score = 32.8 bits (74), Expect = 0.003 Identities = 21/99 (21%), Positives = 47/99 (47%), Gaps = 9/99 (9%) Query: 28 AKLSRSNEQLSDMLYKLNESLRIYQSVLSNNQDQL----KEIKKANSTLNSQRRFFNASQ 83 ++L +N+ L+D + ++ + R ++ + ++A + +N+++ F+A+ Sbjct: 356 SELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAA 415 Query: 84 IRLMDTDALLKQSALELEKLQALEKRLKEGMEQERLIEE 122 D DA L SA+E K +K K+ + L +E Sbjct: 416 KEKSDADAAL-SSAMESRK----KKEDKKRSAENNLNDE 449
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 49.0 bits (117), Expect = 6e-10 Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 4/71 (5%) Query: 11 ALYGGSFDPLHKAHLAIIDQTLELLPFAQLIVLPAYQNPFKKPCFLDAKTRFKELERALK 70 A+Y GSFDP+ HL II++ L F Q+ V +NP K+P F + R +++ +A+ Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRL--FDQVYVAVL-RNPNKQPMF-SVQERLEQIAKAIA 58 Query: 71 GMPRVLLSDFE 81 +P + FE Sbjct: 59 HLPNAQVDSFE 69
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 76.6 bits (188), Expect = 7e-22 Identities = 19/77 (24%), Positives = 40/77 (51%), Gaps = 1/77 (1%) Query: 34 EQKGGEFSKLLKQSINELNNTQEQSDKALADMATGQIK-DLHQAAIAIGKAETSMKLMLE 92 Q F+ L +++ +++TQ + G+ L+ + KA SM++ ++ Sbjct: 27 PQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQ 86 Query: 93 VRNKAISAYKELLRTQI 109 VRNK ++AY+E++ Q+ Sbjct: 87 VRNKLVAAYQEVMSMQV 103
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.013 Identities = 10/38 (26%), Positives = 15/38 (39%) Query: 121 NVNAVVEMADLVEATRAYQANVAAFQSAKNMAQNAIGM 158 VN E +L + Y AN Q+A + I + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 34.9 bits (80), Expect = 3e-04 Identities = 28/183 (15%), Positives = 77/183 (42%), Gaps = 10/183 (5%) Query: 108 NVELLKKLSPDLVVTFVG-NPKAVEHAKKFGISFLSFQETT--IAEAMQAMQ--AQATVL 162 N+ELL ++ P +V G P A+ +F + +A A +++ A L Sbjct: 88 NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 163 EIDASKKFAKMQETLDFIAERL-KNVKKKKGVELFHKAN--KISGHQAISSDILEKGGID 219 + A A+ ++ + + R K + + + G ++ +IL++ GI Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 220 N-FGLKYVKFGRADISVEKIVK-ENPEIIFIWWVSPLTPEDVLNNPKFATIKAIKNKQVY 277 N + + +G +S++++ ++ +++ + + ++ P + + ++ + Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQ 267 Query: 278 KLP 280 ++P Sbjct: 268 RVP 270
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 34.2 bits (78), Expect = 5e-04 Identities = 32/183 (17%), Positives = 74/183 (40%), Gaps = 10/183 (5%) Query: 107 NVELLKKLSPDLVVTFVGNPKAVEHAKKF--GISFLSFQEKTIAEVMEDID---AQAKAL 161 N+ELL ++ P +V G + E + G F K + A L Sbjct: 88 NLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNL 147 Query: 162 EIDASKKLAKMQETLDFIKERL-KDVKKKKGVELFHKAN--KISGHQALDSDILEKGGID 218 + A LA+ ++ + +K R K + + + G +L +IL++ GI Sbjct: 148 QSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIP 207 Query: 219 N-FGLKYVKFGRADVSVEKIVK-ENPEVIFIWWISPLSPEDVLNNPKFSTIKAIKNKQVY 276 N + + +G VS++++ ++ +V+ + + ++ P + + ++ + Sbjct: 208 NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQ 267 Query: 277 KLP 279 ++P Sbjct: 268 RVP 270
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 29.4 bits (66), Expect = 0.030 Identities = 9/23 (39%), Positives = 12/23 (52%) Query: 4 LRYKLLLFVFIGFWGLLVLNLFI 26 KL+LFV + W LL L + Sbjct: 195 TPIKLVLFVALDGWTLLSKGLIL 217