>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.017 Identities = 41/184 (22%), Positives = 71/184 (38%), Gaps = 29/184 (15%) Query: 25 KRMAETIESLVKEIEKVFLKNNSVIAKDVES--LKKISDDLKLFLEDFIPLMRELVKVSV 82 K E + + + K N ++ LKKI D+ LE + L E+ + Sbjct: 53 KTEKEKFKDSINNLVKTEFTNETLDKIQQTQDLLKKIPKDV---LEIYSELGGEIYFTDI 109 Query: 83 DF-KHL-YESLDAMRKSLEDI--EKIASHTELIAINASIEAARAGEAGRNFAVVANEIRT 138 D +H + L K+ + EK+ + + E R + I+ Sbjct: 110 DLVEHKELQDLSEEEKNSMNSRGEKVPFASRFVF-----------EKKRETPKLIINIKD 158 Query: 139 MARDTFKSVGEVKEIEKEIDEKISRLRNSIDTIDKIKEDVDKLVSGINSIVSISDELDLI 198 A ++ +S KE+ EI + IS D I K K + ++ I S+ SD DL+ Sbjct: 159 YAINSEQS----KEVYYEIGKGISL-----DIISKDKSLDPEFLNLIKSLSDDSDSSDLL 209 Query: 199 YRQQ 202 + Q+ Sbjct: 210 FSQK 213
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 185 bits (471), Expect = 6e-53 Identities = 124/509 (24%), Positives = 202/509 (39%), Gaps = 111/509 (21%) Query: 6 IRNFCIIAHIDHGKSTLADRLLEFTGTVSK---RELKEQMLDTLELERERGITIKLNAVR 62 I N ++AH+D GK+TL + LL +G +++ + D LER+RGITI+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 63 MNYEASDGKTYTMHLIDTPGHVDFTYEVSRSLSACEGALLVIDATQGIEAQTIANFFLAL 122 +E + K +++IDTPGH+DF EV RSLS +GA+L+I A G++AQT F Sbjct: 63 FQWE--NTK---VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 123 DAGLEIIPVINKIDLPSANVEWVKEQIADVLG---------------------------- 154 G+ I INKID ++ V + I + L Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDT 177 Query: 155 -LDPDDAILA--------------------------------SAKEGIGIKEILEAIVKK 181 ++ +D +L SAK IGI ++E I K Sbjct: 178 VIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNK 237 Query: 182 VPPPSGDVNKPLKALIFDSFYDNYKGVIPFIRVYDGEIKPGMRIKLMSNNKEFEVVEVGT 241 + L +F Y + + +IR+Y G + + +S ++ ++ E+ T Sbjct: 238 FYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSV-RISEKEKIKITEMYT 296 Query: 242 QSPN-MIKLDSLKAGEVGWLAANIKNIEDTQVGDTITNAENPTKEPCPGFRPAKPMVFAG 300 + K+D +GE+ L + +GDT P +E P++ Sbjct: 297 SINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKL---LPQRERIEN---PLPLLQTT 349 Query: 301 LYPIDSDRYEDLKEALEKLKLNDAALFFE-PETSAALGFGFRCGFLGLLHMEVIKERLER 359 + P + E L +AL ++ +D L + + + FLG + MEV L+ Sbjct: 350 VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIIL----SFLGKVQMEVTCALLQE 405 Query: 360 EFGLELIATAPSVVYKVYLSDGTVIDVQNPAEMPPK--EKIERIEEPYISASIITPAEYV 417 ++ +E+ P+V+Y E P K E IE P P + Sbjct: 406 KYHVEIEIKEPTVIYM---------------ERPLKKAEYTIHIEVP--------PNPFW 442 Query: 418 GSIMQLCQDRRGIQTGFTYLDENRVELRY 446 SI L + +G Y E+ V L Y Sbjct: 443 ASIG-LSVSPLPLGSGMQY--ESSVSLGY 468 Score = 44.1 bits (104), Expect = 1e-06 Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 8/138 (5%) Query: 350 MEVIKERLERE-FGLELIATAPSVVYKVYLS-DGTVIDVQNPAEMPPKEKIER----IEE 403 ME I+ E+ +G + Y +Y S T D + A + ++ +++ + E Sbjct: 478 MEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLE 537 Query: 404 PYISASIITPAEYVGSIMQLCQDRRGIQTGFTYLDENRVELRYDMPLSEILFDFFDKLKS 463 PY+S I P EY+ T L N V L ++P I ++ L Sbjct: 538 PYLSFKIYAPQEYLSRAYTDAPKYCANIVD-TQLKNNEVILSGEIPARCI-QEYRSDLTF 595 Query: 464 VSRGYASFDYELAGYKPS 481 + G + EL GY + Sbjct: 596 FTNGRSVCLTELKGYHVT 613
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 2e-23 Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 5/128 (3%) Query: 6 QNINILTVDDMAAMRKILKTLLAQLGYKNVDEAEDGKQALEILKKNPNKYGLVITDWNMP 65 IL DD AA+R +L L++ GY V + + LV+TD MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGD--GDLVVTDVVMP 58 Query: 66 NMTGIELVQEIRKDPELKNIPILMVTAEAKKENVLMAIKAGVNNYIVKPFTAETLKEKIE 125 + +L+ I+K ++P+L+++A+ + A + G +Y+ KPF L I Sbjct: 59 DENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 126 KIFSSLNK 133 + + + Sbjct: 117 RALAEPKR 124
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 3e-14 Identities = 25/128 (19%), Positives = 53/128 (41%), Gaps = 16/128 (12%) Query: 190 KILILDDSPVARKIIRKILENDGHTVFEAQNGIEALQMLHKWLEEAKTTGRDITDYVQLI 249 IL+ DD R ++ + L G+ V N +W+ L+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLW----RWIAAGD---------GDLV 51 Query: 250 ISDIEMPGMDGLTFTRKVKEDTEFSKIPVIINTSLSDRANVDKSRFVGADAHLVK-FDAP 308 ++D+ MP + ++K+ +PV++ ++ + K+ GA +L K FD Sbjct: 52 VTDVVMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109 Query: 309 DLVKLVHQ 316 +L+ ++ + Sbjct: 110 ELIGIIGR 117
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 30.4 bits (68), Expect = 0.024 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 11/64 (17%) Query: 5 WEKKEIKRLEEELNSLKQKYQNLQKAYDACEKEKESLKEKLSEFSQ-KNLELSKEIEKLK 63 WEKKE +R+E+ L++L++ +A E K+ E++S +SQ + +IE Sbjct: 60 WEKKEAERVEKNLDTLEK---------EALELYKKD-SEQISNYSQTRQYFYDYQIESNP 109 Query: 64 KEKE 67 +EKE Sbjct: 110 REKE 113
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 5e-05 Identities = 10/59 (16%), Positives = 20/59 (33%), Gaps = 8/59 (13%) Query: 383 LVRNALDHGIEPPEERVAKGKPEVGTVKLFAYHEGDHIIVGIQDDGKGIDPEKVKQKAI 441 LV N + HGI P+ G + L + + + +++ G + Sbjct: 263 LVENGIKHGIAQ--------LPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313
>SALVRPPROT#Salmonella virulence-associated 28kDa protein signature. Length = 241 Score = 27.8 bits (61), Expect = 0.024 Identities = 34/152 (22%), Positives = 59/152 (38%), Gaps = 14/152 (9%) Query: 1 MEKSLLQELKELLDLIESFKSEISQISAQKAGFKAINHHIDIAILESEEATKKIIDFIGS 60 M K + KE LD+ + S A GF+ NH D+ I E+ + F G Sbjct: 44 MRKMPVSHFKEALDVPDYSGMRQSGFFAMSQGFQLNNHGYDVFIHARRESPQSQGKFAGD 103 Query: 61 SL------EAVQESLELISQIKVKEDS---TEKAKRLRELLSATTSSLINALTLL----- 106 + V ++ + +S + EDS K + +++ SL TL Sbjct: 104 KFHISVLRDMVPQAFQALSGLLFSEDSPVDKWKVTDMEKVVQQARVSLGAQFTLYIKPDQ 163 Query: 107 EFQDILAQRLLKVKNFLSDIEKSILKIAILAG 138 E A L K + F+ +E + + +++G Sbjct: 164 ENSQYSASFLHKTRQFIECLESRLSENGVISG 195
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 341 bits (875), Expect = e-117 Identities = 117/406 (28%), Positives = 221/406 (54%), Gaps = 3/406 (0%) Query: 1 MAIYTYVGRDILDRKRKGKIEADNEKLAKQLLFSKGIVHI---EKLKEDKSIFKSELDFS 57 MA Y Y D +K +G EAD+ + A+QLL +G+V + E + + + L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 58 FLNRISTKDKLIFTRQLYAMIHAGISIVTALRIIKEQIQNKSLKKIIEDIASHIEEGGKF 117 R+ST D + TRQL ++ A + + AL + +Q + L +++ + S + EG Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 118 STALSKYKNIFGELYISMIRAAEESGTLEETLKRLAEYLEKIEKLRGKIKSALFYPAFVL 177 + A+ + F LY +M+ A E SG L+ L RLA+Y E+ +++R +I+ A+ YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 178 LIATIIIGGILIFIIPTFKALYKDLGGELPSLTQFVIELSNFLRDYVGWIVLGLVLTVVL 237 ++A ++ +L ++P + + LP T+ ++ +S+ +R + W++L L+ + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 238 LVSLRKFKKARYLMDLTLLRLPIIGQLILKASIASFSRTLSSMVSSGLNILNALSISGET 297 + + +K R LL LP+IG++ + A ++RTLS + +S + +L A+ ISG+ Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 298 TNNEVLRRAINGVRNQVEKGISISVALSRYKVFSPMLINMVAIGEEAGNLDEMLSKVADF 357 +N+ R ++ + V +G+S+ AL + +F PM+ +M+A GE +G LD ML + AD Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 358 YEEEVDRTVDALTSLIEPIMMVFIGGIIGFIIIAMYLPIFKIGELI 403 + E + L EP+++V + ++ FI++A+ PI ++ L+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 24.8 bits (54), Expect = 0.025 Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 4 KALIIRLIAIC-TVLLFSSGCVPLLIAGGAGAAA 36 A+ +RL I T L F G +PL I+ GAG+ A Sbjct: 965 MAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 303 bits (777), Expect = 3e-98 Identities = 140/575 (24%), Positives = 257/575 (44%), Gaps = 59/575 (10%) Query: 1 MDYLYIEKCVKELKERILKERVIKIYSDYRLFSVKIGSSFLNIYTGQPNALFFSNENLVS 60 +D +++ + ELK I+ ++ K+ + + LNI G+ + + + Sbjct: 3 LDGIFLYSIIDELKNTIINGKIDKVNQPEKDEII------LNIRKGRLSFKLLISSSSNY 56 Query: 61 SELQGFNI------------------IQGTFVRAVKLPVIDRVIEVETVKLLPSGSFELY 102 + ++ I + + DR++ ++ G +Y Sbjct: 57 PRIHLTDLTKPNPIKAPMFCMVLRKYISNAKIVDIHQINQDRIVVIDFESTDELGFNSIY 116 Query: 103 FLIFELTGKNANVFLLN-QKRKILSLLREV---KSSIRPISRGEIYTFPPQEKK------ 152 LI E+ G+++N+ L+ + I+ ++ + ++ R I G Y +PP+ K Sbjct: 117 SLIIEIMGRHSNMTLIRKRDNIIMDSIKHITPDINTYRSIYPGIEYVYPPKSPKLNPFDF 176 Query: 153 --EFQELEFGKVKREGIEKNLHKFVAGISPLNGKEIAYLFEKFG------NLQKAYEEFL 204 + E + + + K G+S EI + + NL++ E Sbjct: 177 SYDMIENFTKENSLQLNDNIFSKIFTGVSKTLSSEICFRLKNNSIDLSLSNLKEIVEVCK 236 Query: 205 RKHKESKSAFLYYE-KGKPKYMTTFFYQSLKNLEFKKFSGNFPYTKCWEFYYREKIEKEK 263 KE +S + K F+ +L + E K +K E +Y K + ++ Sbjct: 237 DLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMSKEDYKKIQYDSSSKLLENFYYAKDKSDR 296 Query: 264 VDSLKKSLLKDVEKRIEALKKEIEALKSKEELLKEAEENRKLGELLKYNLNSLKPGKKSV 323 + S L K V I K+ + L + + ++ + + GELL N+ +LK G + Sbjct: 297 LKSKSSDLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANIYALKKGLSHI 356 Query: 324 KVFDYYTNQ--EIEVPIDPSVSPQKNVEKYFSKYRKLKRKAEYEETLRKKLEEELLEQEF 381 ++ +YY+ +++ +D + +P +NV+ Y+ KY KLK+ E + EEEL Sbjct: 357 ELANYYSENYDTVKITLDENKTPSQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNYLYS 416 Query: 382 LKSSINEKESLEELKSFLPE------------TKEKEKRKKNFKVYILPSGRKIVVGRSS 429 + ++IN ++ +E++ E K K+ + +I G I VG+++ Sbjct: 417 VLTNINNADNYDEIEEIKKELIETGYIKFKKIYKSKKSKTSKPMHFISKDGIDIYVGKNN 476 Query: 430 RENEFLSLKLANPWDIWFHAKEIPGSHVILRLEKGEKPSEEDIVLSAATAAFFSRGKQSG 489 +N++L+LK AN DIWFH K IPGSHVI++ E ++ +A AA++S+ + S Sbjct: 477 IQNDYLTLKFANKHDIWFHTKNIPGSHVIVK--NIMDIPESTLLEAANLAAYYSKSQNSS 534 Query: 490 KVAVDYTEVKNLKKPKGAPPGFVVYENEKTIFVNP 524 V VDYTEVKN+KKP GA PG V+Y +TI+V P Sbjct: 535 NVPVDYTEVKNVKKPNGAKPGMVIYSTNQTIYVTP 569
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.029 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>PF01540#Adhesin lipoprotein Length = 475 Score = 32.4 bits (73), Expect = 0.008 Identities = 56/254 (22%), Positives = 107/254 (42%), Gaps = 24/254 (9%) Query: 186 ELKEVKEDGTIVLKVLYSERGKKTKE--KEIIKQVKKVYKHSRLTEEYLNKAIKTFEKQA 243 EL E+K + L +E +K KE KE++K +K+ + + K + F+ Sbjct: 226 ELAEIKAEDDKKL----AEENQKIKEGAKELLKLSEKIQSFADTIALTITKLERKFQIDE 281 Query: 244 NVDYFINKNAEKFLKEQFDLWMYQYLFSQEASFDLKRFQELQALKNIAYRIIEFIAQFED 303 + E K+ ++ + + + + F L EL++ K +E I + Sbjct: 282 KFKKQLISTIELLNKKSVEVKTFATVNTIKKDFLL---SELESFKEFNTSWLEKIVSEWE 338 Query: 304 ELRKIWEKPRLVFNSNYVITL-DRIANKEEGKEILEEIISQLKEQEKEFKKSINQLKKIK 362 E++K W K + L + + G E L++I ++ E K K+I +L+K Sbjct: 339 EVKKAWSKELAEIKAEDDKKLAEENQKIKNGVEELKKINNEAFELSKTVNKTIAELEKKF 398 Query: 363 ENYKSYKERFENH-----QIKNQLEEWYLLDIIEEGFGVDGILKNGELNEKWKFLPVDTK 417 + S+KE+ +N Q++E+ + +EGF L E F + T Sbjct: 399 KIDVSFKEQLKNFADDLLDKSRQIDEFTTVTSTQEGF---------TLAELESFKEITTT 449 Query: 418 YFNGLKEKIEEIFD 431 +FNG+K + + + Sbjct: 450 WFNGMKSEWARVQE 463
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 74.6 bits (183), Expect = 7e-18 Identities = 14/81 (17%), Positives = 37/81 (45%), Gaps = 5/81 (6%) Query: 210 IEKKKFYPRLAKRFGIEGKVILKIVIDRKGNLESVSIVKTSGSKVLDKAALKLIKKCKFP 269 + YP A+ IEG+V +K + G +++V I+ + + ++ +++ ++ Sbjct: 161 SRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYE 220 Query: 270 PLPPEYKKDDFEVEIPIRYEL 290 P P + + I +++ Sbjct: 221 PGKPGSG-----IVVNILFKI 236
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 32.5 bits (74), Expect = 3e-04 Identities = 25/148 (16%), Positives = 60/148 (40%), Gaps = 10/148 (6%) Query: 13 ADKIIELLNKALCDEWLAYYQ----YWIGSKVVKGPMKDAVIAELIQHANDELRHADMLV 68 + LN L + +L Y + +W VKGP + + + + D + Sbjct: 10 QTLVENSLNTQLSNWFLLYSKLHRFHW----YVKGPHFFTLHEKFEELYDHAAETVDTIA 65 Query: 69 TRILELGGTPVLSPKQWFELTNCGYDAPVDPFVKIVLEQNIKGEQCAIDTYSEILKIT-K 127 R+L +GG PV + K++ E + D + +++ + + ++ + + Sbjct: 66 ERLLAIGGQPVATVKEYTEHASIT-DGGNETSASEMVQALVNDYKQISSESKFVIGLAEE 124 Query: 128 DIDPITYNIALQILTDEVEHEEDLQSFL 155 + D T ++ + ++ + + L S+L Sbjct: 125 NQDNATADLFVGLIEEVEKQVWMLSSYL 152
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 39.3 bits (91), Expect = 9e-06 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 25/92 (27%) Query: 144 ELLRRVNSVPVSLVLAQGAIESGWGTSRFFIE----GNNVFGMYAF-------------- 185 +L + + VP L+LAQ A+ESGWG + E N+FG+ A Sbjct: 161 QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTE 220 Query: 186 YTTN--KKLKARNGNVYLKVYDDILQSVEDYI 215 Y KK+KA+ +VY L+++ DY+ Sbjct: 221 YENGEAKKVKAK-----FRVYSSYLEALSDYV 247
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 2e-08 Identities = 46/277 (16%), Positives = 90/277 (32%), Gaps = 12/277 (4%) Query: 460 EKEKFLLDSKKEIDNSIKVL-KQLKKKKEKLKELMDSLEKKVEKFLQLEERKNQLIRDRE 518 K L + K + + L ++L KEKL++ SL +K K +LE RK L + E Sbjct: 71 LKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALE 130 Query: 519 RFLEEVKELKNKLNKLSFNYDRLRKTEELFTSLKEQVAALEEKKKNLEREAKELETKKAN 578 + K+ L L++ + + K LE +KA Sbjct: 131 GAMNFSTADSAKIKTLE---AEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 187 Query: 579 LSKNYD--TKLKEELQNRLKSLKTKEFFFLNKIKKIKEEHNLCVSSAKEVDIKLKELETT 636 L K E N + K + + + + Sbjct: 188 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 247 Query: 637 KEKLNKIQGEARNLNFYYGEKKKKEDLIKSLEKEVLSVQEEIEKLNYSEEEYLTLEETYE 696 + L + + + E ++ + +I+ L + + E Sbjct: 248 IKTLEAEKAALEA------RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLE 301 Query: 697 KQKERVESLEKELSRELGKLETLEKQLKVNIKKLKQK 733 Q + + + + L R+L +KQL+ +KL+++ Sbjct: 302 HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Score = 50.1 bits (119), Expect = 3e-08 Identities = 69/387 (17%), Positives = 134/387 (34%), Gaps = 17/387 (4%) Query: 353 KKELRETEKVFKELKTLEKSFREITIRLSDKQKDLKSLDERIRELPRIEKAKELSKKKKD 412 +K +K E TL+ +++ + L E + EK ++ K + Sbjct: 53 EKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNA--KEKLRKNDKSLSE 110 Query: 413 TLKELENTDKEIATIEAKLEEVEKRIK-ILESSESLSCPVCGSPMDKVEKEKFLLDSKKE 471 +++ + A +E LE ++L K + EK L + Sbjct: 111 KASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNF 170 Query: 472 IDNSIKVLKQLKKKKEKLKELMDSLEKKVEKFLQLEERKNQLIRDRERFLEEVKELKNKL 531 +K L+ +K L+ LEK +E + + I+ E + K L Sbjct: 171 STADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 230 Query: 532 NKL-SFNYDRLRKTEELFTSLKEQVAALEEKKKNLEREAKELETKKANLSKNYD--TKLK 588 K + +L+ + AALE ++ LE+ + S K Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 589 EELQNRLKSLKTKEFFFLNKIKKIKEEHNLCVSSAKEVDIKLKELETTKEKLNK-IQGEA 647 L+ L+ + + ++ + + + K+++ + ++LE + Q Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 350 Query: 648 RNLNFYYGEKKKKEDLIKSLEKEVLSVQEEIEKLNYSEEEYLTLEETYEKQKERVESLEK 707 R+L+ KK+ E + LE++ SE +L + +E + +EK Sbjct: 351 RDLDASREAKKQLEAEHQKLEEQNKI----------SEASRQSLRRDLDASREAKKQVEK 400 Query: 708 ELSRELGKLETLEKQLKVNIKKLKQKE 734 L KL LEK K + K E Sbjct: 401 ALEEANSKLAALEKLNKELEESKKLTE 427 Score = 42.4 bits (99), Expect = 7e-06 Identities = 54/371 (14%), Positives = 118/371 (31%), Gaps = 25/371 (6%) Query: 216 RAELAQEKALLDNQEKLCKNYREKRNEYNKLRESLRNLKNLLEGTTEEVKRLNQKIVEIE 275 R++ + + + +K + + + L + + LK+ + TEE+ +K+ + + Sbjct: 46 RSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105 Query: 276 KQQALIPQIEKELKILDPLKMIRAILDEISQLRLEEKEIESKLKELENIEKELLELSKKV 335 K + EK KI + + + +K+K LE + L + Sbjct: 106 KSLS-----EKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160 Query: 336 PKLKETFRETELLLEHKKKELRETEKVFKELKTLEKSFREITIRLSDKQKDLKSLDERIR 395 K E K K L + + + + E + S E + Sbjct: 161 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 220 Query: 396 ELPRIEKAKELSKKKKDTLKELENTDKEIATIEAKLEEVEKRIKILESSESLSCPVCGSP 455 + +L K + + +I T+EA+ +E R LE + Sbjct: 221 AALA-ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE--------- 270 Query: 456 MDKVEKEKFLLDSKKEIDNSIKVLKQLKKKKEKLKELMDSLEKKVEKFLQLEERKNQLIR 515 F +I L+ +K L+ L + + + + + Sbjct: 271 ----GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKK 326 Query: 516 DRERFLEEVKELKNKLNKLSFNYDRLRKTEELFTSLKEQVAALEEKKKNLEREAKELETK 575 E ++++E + + +E LE + + LE + K E Sbjct: 327 QLEAEHQKLEEQNKISEA------SRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEAS 380 Query: 576 KANLSKNYDTK 586 + +L ++ D Sbjct: 381 RQSLRRDLDAS 391 Score = 35.0 bits (80), Expect = 0.001 Identities = 34/241 (14%), Positives = 87/241 (36%), Gaps = 11/241 (4%) Query: 500 VEKFLQLEERKNQLIRDRERFLEEVKELKNKLNKLSFNYDRLRKTEELFTSLKEQVAALE 559 + +++ER ++ + + +L L + D L + + KE++ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELS---NAKEKLRKND 105 Query: 560 EKKKNLEREAKELETKKANLSKNYDTKLKE--ELQNRLKSLKTKEFFFLNKIKKIKEEHN 617 + + +ELE +KA+L K + + ++K+L+ ++ + +++ Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE 165 Query: 618 LCVSSAKEVDIKLKELETTKEKLNKIQGEARNLNFYYGEKKKKEDLIKSLEKEVLSVQEE 677 ++ + K+K LE K L Q E + + + ++ +++ E Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEK------ALEGAMNFSTADSAKIKTLEAE 219 Query: 678 IEKLNYSEEEYLTLEETYEKQKERVESLEKELSRELGKLETLEKQLKVNIKKLKQKESDI 737 L + + E + K L E LE + +L+ ++ + Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 738 K 738 Sbjct: 280 S 280
>SECA#SecA protein signature. Length = 901 Score = 32.9 bits (75), Expect = 0.005 Identities = 16/64 (25%), Positives = 35/64 (54%), Gaps = 1/64 (1%) Query: 425 RKTEGQIDHLISEIKKRVEKNERILITTLTKKSAEELSKYLLEKGIKAKYMHSEIDSVER 484 +I +I +IK+R K + +L+ T++ + +E +S L + GIK ++++ + E Sbjct: 429 MTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE- 487 Query: 485 VEII 488 I+ Sbjct: 488 AAIV 491
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.030 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 83.4 bits (206), Expect = 1e-18 Identities = 68/282 (24%), Positives = 104/282 (36%), Gaps = 80/282 (28%) Query: 389 ITVMGHVDHGKTTLLDYI-----RNTKVAEREAG-------------GITQHIGASVVEV 430 I V+ HVD GKTTL + + T++ + G GIT I + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGIT--IQTGITSF 63 Query: 431 DTSEGKKKLVFLDTPGHEAFTAMRARGAQVTDIAVLVVAADDGVMPQTVEAINHAKAAGV 490 K ++ DTPGH F A R V D A+L+++A DGV QT + + G+ Sbjct: 64 QWENTKVNII--DTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 491 PIIVAINKIDKPGANPDRVKQE----LTQHGLI-----------------AEDWG----- 524 P I INKID+ G + V Q+ L+ +I +E W Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 525 ---------------------------GDTVMVPV---SAKTGEGVDELLEMIALQAELM 554 + + PV SAK G+D L+E+I + Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFY 239 Query: 555 ELKANPDKPARGVVLEAKLDRQRGPVATLLIQSGTLKQGDAI 596 G V + + +R +A + + SG L D++ Sbjct: 240 SSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSV 281
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 51.1 bits (122), Expect = 4e-10 Identities = 46/235 (19%), Positives = 81/235 (34%), Gaps = 43/235 (18%) Query: 6 RFLLAFILALFLE----AGFIYIVKNLH--KPHKQEVKQVIKISLLKNEKKPKVLVTKQK 59 RF +L++ + AG +Y + P + V ++ E V + Sbjct: 13 RFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEP 72 Query: 60 KI--------VKEPKQKKKVVIPKEKPKVVTKKPQKKIPQEEKKEV----------LEKK 101 + + EP ++ VVI K KPK K K ++ K++V E Sbjct: 73 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132 Query: 102 KPGGLKPL----QGNLPAYYVDAIKKAIEE-NIFYPLEAIERGEEGVVSVKFVLDKSG-- 154 P + P V + +A+ YP A EG V VKF + G Sbjct: 133 APARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRV 192 Query: 155 ---KVIKCKPFSGKSEILQKATCIAIERAKFPPIPQTIKNE-----RITFHLEIE 201 +++ KP + + ++ A+ R ++ P +I EI+ Sbjct: 193 DNVQILSAKP----ANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 243
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 5e-05 Identities = 29/183 (15%), Positives = 59/183 (32%), Gaps = 11/183 (6%) Query: 494 EEVIETARSLMTAEDRLAEDIIAALEKEYRKLTEEKETVE---RLKEALKKKEEELQKKE 550 E V E ++ ++ +D + E K V+ + E + E + + Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 551 KELKEKSAREIEKFIEELKKKSEEVFKKAKSEKAKQEIRQIVI-----TAKNRAKALAEA 605 E KE + E E+ + +K++EV K KQE + V +N + Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 606 KEVREVKPGNTVKLLKSGRKGKVLEVDK---ERKVAKVLVGGLKVDVKLSQIEPVEETVK 662 + + +T + K V + V+ +Q E+ Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 663 QEE 665 + + Sbjct: 1218 KPK 1220
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.023 Identities = 8/57 (14%), Positives = 22/57 (38%) Query: 149 LSEAKSAVEIAESYLQAARRHLKDVKAFFDEGIVPKRDLLEAKVRVRDAEEQLEKAR 205 + + E+ + + L D + + + K +LE + + +A +L + Sbjct: 216 RLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYK 272
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (311), Expect = 1e-32 Identities = 90/406 (22%), Positives = 165/406 (40%), Gaps = 28/406 (6%) Query: 17 FMTLLDTTIVDIVLPHMMSTFEAKPDDIQWVITSYMIASAIAMPVVGWLGGKIGHRNTYL 76 F ++L+ ++++ LP + + F P WV T++M+ +I V G L ++G + L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 77 LGIGLFTTMSTLCGIAPN-LETMILGRVFQGIGEGLAVPMSMTLLFELFPPEKRGIAMGM 135 GI + S + + + +I+ R QG G + M ++ P E RG A G+ Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 136 FALGATFGPSLGPTIGGYLTEHLDWRWVFYVNLLPGILVIYLLMLLIKDDRKKHVADGKL 195 G +GP IGG + ++ W ++ L+P I +I + L+K +K+ G Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLL---LIPMITIITVP-FLMKLLKKEVRIKGHF 199 Query: 196 DILGFILLAISLSSLITALSKGNDWGWSDEKTVLLLYTFSVSLILFILVELKVENPLVNL 255 DI G IL+++ + + + + L +S ++F+ KV +P V+ Sbjct: 200 DIKGIILMSVGIVFFMLF-TTSYSISF--------LIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 256 GLFKFTFFRYPVFSLTLFGMGVYASYFLLPLYLEKLRKFPTIEAGEILFCPAAATGIVS- 314 GL K F V + V ++P ++ + + T E G ++ P + I+ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 315 LISGILMDRKILSRKASIVIGILIFIFGTHLQSKLDLEMGKTQIILFLLPWGIGMGFFFP 374 I GIL+DR+ +I + L F L F+ I Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSF-------LTASFLLETTSWFMT-IIIVFVLGGL 362 Query: 375 ALSQVSLGNFKGEILRQASA-----LQNLLRLVGGSVGTALSTHIL 415 + ++ + L+Q A L N + G A+ +L Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 98.0 bits (244), Expect = 3e-24 Identities = 66/384 (17%), Positives = 134/384 (34%), Gaps = 48/384 (12%) Query: 50 ASGKIVKLFKKEYESVSKEEPLFKVDDSLYRKDVEILKAKLESLKQKKKELSEKLSRLKE 109 + + ++ KE ESV K + L K+ D ++ L + ++ ++ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 110 QLPADVKISKENLKALEKKLNQLKYQELMEKTNYETSTQKAESSLKAAEK---------G 160 ++K+ E + L+ L+++ QK + L +K Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 161 LEAAKVSFNHWKNQYNRYKRLYKKRIISKEQLEEVELAYKEALYKLESAKARLQAAKGDL 220 + + K++ + + L K+ I+K + E E Y E A L+ K Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVE-------AVNELRVYKS-- 273 Query: 221 ENAKSLKNRIAIIRKQQEEVKNKIEALKEQVKISKANLKKINELSHSIRQLEEDIKSIES 280 ++ I + K + + + + K NE+ +RQ ++I + Sbjct: 274 --------QLEQIESEILSAKEEYQLVTQLFK---------NEILDKLRQTTDNIGLLTL 316 Query: 281 QIEKAKILLSHTLVKSPVEGFIAK-KWKEEGDFISPGLPVYSIY-NSKSFFVLAWIEEDK 338 ++ K + +++++PV + + K EG ++ + I + V A ++ Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKD 376 Query: 339 IKDIKVGNKVKVELEVCKKTFKGKVYSIGTSAGSIFSLIPRDTSQ----GEYTKVTQRIP 394 I I VG +++E F Y G G + I D + G V I Sbjct: 377 IGFINVGQNAIIKVE----AFPYTRY--GYLVGKV-KNINLDAIEDQRLGLVFNVIISIE 429 Query: 395 VKIKVEKVPPVCIKPGTNVTVYIK 418 + + G VT IK Sbjct: 430 ENCLSTGNKNIPLSSGMAVTAEIK 453
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 510 bits (1314), Expect = 0.0 Identities = 172/475 (36%), Positives = 266/475 (56%), Gaps = 38/475 (8%) Query: 5 MEKRKVLIIEDDDIQRELLKEILKESGFEVFTSSTAEKGLQTVAKNSPAVVVTDVRLPGM 64 M +L+ +DD R +L + L +G++V +S A + +A +VVTDV +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 65 DGLTFLKKLKQEHSEIEVIVITAFSNVEDAVSAIKAGAFHYVTKPFDPQVLINLIDKAC- 123 + L ++K+ ++ V+V++A + A+ A + GA+ Y+ KPFD LI +I +A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 124 ----QLASLRKIPKKDGEIIYASKLMEELLEKASLFAKTEAPVLILGESGVGKELIARFI 179 + + L + ++ S M+E+ + +T+ ++I GESG GKEL+AR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 180 HKESGRK-GKFVSVNCAAIPSELFESELFGYEKGAFTGALRSKPGLFEEADGGTIFLDEV 238 H R+ G FV++N AAIP +L ESELFG+EKGAFTGA G FE+A+GGT+FLDE+ Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 239 GELPLNLQAKFLRVLQENEVRRVGGTQTKKVDVKVVAATNRDLGELVKKGDFREDLYYRL 298 G++P++ Q + LRVLQ+ E VGG + DV++VAATN+DL + + +G FREDLYYRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 299 NVLTLRIPPLRERPEDILELTGFFLRKFSKKYNKKVEITPEALQILLSYSFPGNVRELEN 358 NV+ LR+PPLR+R EDI +L F+++ K+ EAL+++ ++ +PGNVRELEN Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 359 LIHRLVI-TSMDKIRPEDLTDLKEKE-------------------------------NHC 386 L+ RL D I E + + E + Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 387 NEIDFSKPLPEKLAEFEKKMIEEALKRSDYVQVKAAKLLGIDEKSLRYKRKKYGI 441 + + S LAE E +I AL + Q+KAA LLG++ +LR K ++ G+ Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.028 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.3 bits (68), Expect = 0.018 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 4/63 (6%) Query: 369 DAFKEYADKMKEVGVKI--YVRRGGPNYEVGLARIKKAAEELGLPIEVYGPETHITAIVK 426 DA K+ A++ + G ++ + + L + + A+ELG IEV E + TAI K Sbjct: 33 DALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELG--IEVQYDEKNGTAITK 90 Query: 427 KAL 429 + Sbjct: 91 QVF 93
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.044 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 249 ATMMRVSDPAIFGDAIRVYYKE--LFEKHGKELEEIGFDPNKGLIDLEN 295 A + R D + G + YY+E EK E ++ FDP KG IDL + Sbjct: 488 AGVTRNGDKTLSGKSYIDYYEEGKRLEKKXDEFQKQVFDPLKGNIDLSD 536
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 38.9 bits (90), Expect = 6e-07 Identities = 20/94 (21%), Positives = 43/94 (45%), Gaps = 9/94 (9%) Query: 10 WDIANIKQIK---------NESEAIKEFEAYFVRIFLKEARKSIPKGLFNTSFSANFYYD 60 WD ++ ++K N ++ E FV++ LK R ++PK +S Y Sbjct: 13 WDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYTS 72 Query: 61 MLDMELAEVISQKDPLHLEKFLQEALSKYQKISK 94 M D ++A+ ++ L L + + + ++ Q + + Sbjct: 73 MYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPE 106
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 36.2 bits (83), Expect = 2e-04 Identities = 25/139 (17%), Positives = 50/139 (35%), Gaps = 8/139 (5%) Query: 17 QAKRELGEEIDILYYEVEKERSFLPFFRKKKYKLFVVPKEKRENNEIEKLEEELNEVREL 76 +EL E + L PFF + ++ + + ++ E +N + Sbjct: 245 AKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINAD 304 Query: 77 LTNIKSSL--EENKLANSSLPIPEHIDSTSSCEENLTTEFTGDALELIKVLIQK-----G 129 +T I+ ++ N + E ++ + NL DA++ Q G Sbjct: 305 ITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYG 364 Query: 130 VK-KNIAEELVKEACGLDI 147 K +A+EL ++ G I Sbjct: 365 EKYSKMAQELADKSKGKKI 383
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 57.4 bits (138), Expect = 1e-14 Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 1/81 (1%) Query: 16 KEKHNQKANGFKDLLENFIKDVNSDLKESRKAEENLISGNVQ-NIEEIMYKIEKADLSLR 74 +E Q F L + ++ +R E G + ++M ++KA +S++ Sbjct: 23 QESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQ 82 Query: 75 LLVEIRNKALESYQEIMRMQV 95 + +++RNK + +YQE+M MQV Sbjct: 83 MGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 357 bits (917), Expect = e-119 Identities = 170/558 (30%), Positives = 290/558 (51%), Gaps = 54/558 (9%) Query: 7 QTKVQEIFKK-NANPKNVILLLSALTLVSFLAFIAIKQSTTEDYAVLYTHLSPDDAGSIL 65 Q K E + ANP+ I L+ A + + + + T DY L+++LS D G+I+ Sbjct: 9 QPKPLEWLNRLRANPR--IPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIV 66 Query: 66 SVLQEEHIPYKVEGNGSIILVPKEKVYDIRLKLAAKGLPHGKVVGFELFDEPKLGITQFQ 125 + L + +IPY+ I VP +KV+++RL+LA +GLP G VGFEL D+ K GI+QF Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 126 ENVEFLRALEGEIERTIKRINAIQDVKVNIALPKDSIFVRESEEPKASILVNLWPGRELT 185 E V + RALEGE+ RTI+ + ++ +V++A+PK S+FVRE + P AS+ V L PGR L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 186 KEQVKAIVFLVSHAVPGLKPENVTVIDNRGRVLTDLLSGNEDETGSSKELEVKRKLEKEI 245 + Q+ A+V LVS AV GL P NVT++D G +LT S + +L+ +E I Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQ--SNTSGRDLNDAQLKFANDVESRI 244 Query: 246 ERKIQSMLSQVLGSGKVVVRASVEIETGRLEKKEELYDPDMTAVVSERKIQEKETGIK-- 303 +R+I+++LS ++G+G V + + +++ E+ EE Y P+ A + + ++ + Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 304 -PKEQGVPGTTTNVP-PVLNLNQGNEILKKE----------------------KKDVTTN 339 GVPG +N P P ++ +++ T+N Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 340 YDVSKTIQKTITPIFKIKRISVGVLVDGKYQKEKDKAGNEIIKFVPRSQEEIKTYEEIVK 399 Y+V +TI+ T + I+R+SV V+V+ K + K +P + +++K E++ + Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADG--------KPLPLTADQMKQIEDLTR 416 Query: 400 SAIGYDPKRGDTVTVASVPFEAKQFVQKEK---SQKKFPWIYIAAGGGLLTLILVGIIAL 456 A+G+ KRGDT+ V + PF A E Q+ F +AAG LL L++ I+ Sbjct: 417 EAMGFSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWR 476 Query: 457 KLLKSK--------KTEPQQPEIPETLMAEMKARAEHKEEL----EELHIESDPLYIKIV 504 K ++ + K +Q ++ + ++ R E+L + ++ + +I Sbjct: 477 KAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIR 536 Query: 505 EIAKEHPELVANVISKWI 522 E++ P +VA VI +W+ Sbjct: 537 EMSDNDPRVVALVIRQWM 554
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.9 bits (106), Expect = 7e-07 Identities = 16/52 (30%), Positives = 31/52 (59%) Query: 516 VISKVRSGMLEMSNVDIASEFINLITAQRAYQANARVITTDDQILQETMNIK 567 V++++ + +S V++ E+ NL Q+ Y ANA+V+ T + I +NI+ Sbjct: 495 VVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 33.8 bits (77), Expect = 0.002 Identities = 15/59 (25%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Query: 4 SFYTAFTGLNADKTWLSVISDNIANVNTVGFKKENAVFEDLLARSLTTFKNGAPVNQEI 62 A +GLNA + L+ S+NI++ N G+ ++ + +A++ +T G V + Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI----MAQANSTLGAGGWVGNGV 57
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 53.8 bits (129), Expect = 5e-13 Identities = 20/73 (27%), Positives = 46/73 (63%) Query: 8 LEDFKDVSLSISLCIGKKFLTLNKILKLKEGDLIEFDKKLEDYLDVYLNGQKFGIGELVI 67 ++ D+ + +++ +G+ +T+ ++L+L +G ++ D + LD+ +NG GE+V+ Sbjct: 54 IDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVV 113 Query: 68 VNDKYSLRLVDLV 80 V DKY +R+ D++ Sbjct: 114 VADKYGVRITDII 126
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 234 bits (598), Expect = 6e-80 Identities = 100/208 (48%), Positives = 151/208 (72%), Gaps = 1/208 (0%) Query: 35 GNLDITLKILFLITILSLAPAILITVTSFTRIVIILSLLRHALGTPQTPPNQVIIALSLF 94 + + ++ L IT L+ PAIL+ +TSFTRI+I+ LLR+ALGTP PPNQV++ L+LF Sbjct: 36 QSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALF 95 Query: 95 LTLFTMAPTFQQIDELAIQPYINKKISDVEAIKRASEPIKNFMLRNTRKEDLKLFLDIRN 154 LT F M+P +I A QP+ +KIS EA+++ ++P++ FMLR TR+ DL LF + N Sbjct: 96 LTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLAN 155 Query: 155 E-KPSSPQEISMLTLIPAFMVSEIRTALEVVFVIFLPFIVIDLLVASILMSMGMMMIPPM 213 P+ + M L+PA++ SE++TA ++ F IF+PF++IDL++AS+LM++GMMM+PP Sbjct: 156 TGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPA 215 Query: 214 MLSLPFKLILFVLSDGWELLIKSIILSY 241 ++LPFKL+LFVL DGW+LL+ S+ S+ Sbjct: 216 TIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 59.8 bits (145), Expect = 1e-15 Identities = 21/77 (27%), Positives = 41/77 (53%) Query: 3 VDQVITLGQKMLEIALLVGMPVLLTTFLVGIIISIFQAATQIHEMTLTFIPKIVAALLAL 62 +D ++ G K L + L++ + ++G+++ +FQ TQ+ E TL F K++ L L Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60 Query: 63 FIFGSWMLIKLIDYTKE 79 F+ W L+ Y ++ Sbjct: 61 FLLSGWYGEVLLSYGRQ 77
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 99.0 bits (247), Expect = 6e-27 Identities = 55/251 (21%), Positives = 113/251 (45%), Gaps = 5/251 (1%) Query: 9 TFSLFLLTFVRVASFFLAFPFISTTLIPLNIRILLILAFSFYLSQIIEPSQMIDITKIDL 68 +L+ +RV + P +S +P +++ + ++ I PS + + Sbjct: 12 WLNLYFWPLLRVLALISTAPILSERSVPKRVKL----GLAMMITFAIAPSLPANDVPVFS 67 Query: 69 LSFFLLVIKEVLLGISFSILTTIYSSIFIHAAELISYSMGLTIVNIFDSTFGS-ISVLSR 127 L ++++L+GI+ + A E+I MGL+ D + VL+R Sbjct: 68 FFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLAR 127 Query: 128 FFVYIFYVVFFFTDAYKIFIAAFVESFKIIPIGNFHLSDSLLYFFLKESKLIFFLSFKIA 187 + ++F + + I+ V++F +PIG L+ + K LIF +A Sbjct: 128 IMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLA 187 Query: 188 FPFIITLFITNLILALVNRLIPQINVFIVGLPLQIFIGLFFLSTGFSILIYSSKYLIEKL 247 P I L NL L L+NR+ PQ+++F++G PL + +G+ ++ ++ ++L ++ Sbjct: 188 LPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEI 247 Query: 248 STDIINLIKIL 258 + ++I L Sbjct: 248 FNLLADIISEL 258
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 328 bits (843), Expect = e-114 Identities = 105/341 (30%), Positives = 178/341 (52%), Gaps = 3/341 (0%) Query: 7 KTEKATPRRRQKAKEEGQVLKSQDIPIAFTLLITSTLLYFYIPFAYKKLLQLFTFDFRTS 66 KTE+ TP++ + A+++GQV KS+++ ++ S +L + ++ +L S Sbjct: 5 KTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQS 64 Query: 67 NNVNLWN-NYLVS--AKTFALLILPVFLVLFLGGIFSNIIQFGFLFSLKPLLPKLDNINP 123 +Y+V F L P+ V L I S+++Q+GFL S + + P + INP Sbjct: 65 YLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKINP 124 Query: 124 IKGLGRLFSLKTLFETFRNTLKLIIALAVGYFSGKYILSDFFSLSFISLNNQIILMLKYT 183 I+G R+FS+K+L E ++ LK+++ + + K L L + L+ + Sbjct: 125 IEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQIL 184 Query: 184 LLLFFIFGLLSLPIAAADFLFRRWEYEENLKMSKEEIKEERKQYEGHPLIKSAIRRKQRE 243 L I + + I+ AD+ F ++Y + LKMSK+EIK E K+ EG P IKS R+ +E Sbjct: 185 RQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFHQE 244 Query: 244 IAMKRMMAEIPKADVVITNPTHYAVALRYERGKMHAPKVIAKGVDNIALKIKKIALEHNI 303 I + M + ++ VV+ NPTH A+ + Y+RG+ P V K D ++KIA E + Sbjct: 245 IQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGV 304 Query: 304 PIEENPYLARVLYESCDIGSFIPEEFYQAIAKILAKVYKKK 344 PI + LAR LY + +IP E +A A++L + ++ Sbjct: 305 PILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.031 Identities = 14/75 (18%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 21 QEIEKHEAQKEIERLKKLKVEVQRLLEEKKNLLKKIEEEKKQLEEEKKAFEKKIKEIESE 80 ++ + E+ + E Q E K +EEK ++E EK K+ S Sbjct: 1074 SNVKANTQTNEVAQSGSETKETQTT--ETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 81 RYKKLAQIFEKMDPE 95 + ++ + + +P Sbjct: 1132 KQEQSETVQPQAEPA 1146
>FLAGELLIN#Flagellin signature. Length = 507 Score = 120 bits (302), Expect = 3e-33 Identities = 59/233 (25%), Positives = 105/233 (45%), Gaps = 7/233 (3%) Query: 2 ALRINYNYQSDFTHFNLLQTEANMNKSLERLATGYRINRAADDAAGLYIADQLKTYAVSL 61 A IN N S T NL +++++++ ++ERL++G RIN A DDAAG IA++ + L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 EQATRNAHDGISIAQIAQSALTNVYNILNDIKAKAIEAANDSQDSATRQIIQQDINKLVD 121 QA+RNA+DGISIAQ + AL + N L ++ +++A N + + + IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 VIGKIFTDTEFNGINVFSSGTAVTFTIHYGGRSGQELLMQGATASAAAAADTSAPSTITL 181 I ++ T+FNG+ V S + G G+ + + + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKI--QVGANDGETITIDLQKIDVKSLGLDG-----FN 173 Query: 182 GNTGYTLDVTSQTKAEATISTVDALIKEVDKLNAKYGSYQIELEKLITNNESQ 234 N V + ++ D +K S + + + Sbjct: 174 VNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDK 226 Score = 100 bits (249), Expect = 5e-26 Identities = 56/286 (19%), Positives = 101/286 (35%), Gaps = 5/286 (1%) Query: 5 INYNYQSDFTHFNLLQTEANMNKSLERLATGYRINRAADDAAGLYIADQLKTYAVSLEQA 64 + + + L +A N +++ T A+ A K + Sbjct: 223 VPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKG 282 Query: 65 TRNAHDGISIAQIAQSALTNVYNILNDIKAKAIEAANDSQDSATRQIIQQ----DINKLV 120 D + T + + I A + D+AT Q + +N Sbjct: 283 VTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQF 342 Query: 121 DVIGKIFTDTEFNGINVFSSGTAVTFTIHYGGRSGQELLMQGATASAAAAADTSAPSTIT 180 K ++ ++ I G A + Sbjct: 343 TFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTM-FIDKTASG 401 Query: 181 LGNTGYTLDVTSQTKAEATISTVDALIKEVDKLNAKYGSYQIELEKLITNNESQRINSQE 240 + ++ ++++D+ + +VD + + G+ Q + ITN + N Sbjct: 402 VSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNS 461 Query: 241 AESRIRNVDFAKEMSEFTRNQILMQSGTAMLAQANQLPQLVLQLLR 286 A SRI + D+A E+S ++ QIL Q+GT++LAQANQ+PQ VL LLR Sbjct: 462 ARSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 96.4 bits (240), Expect = 8e-25 Identities = 68/347 (19%), Positives = 128/347 (36%), Gaps = 49/347 (14%) Query: 3 KALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGDSSNWRLKELGIE----KDVKVVYMD 58 K L+TG G G +++K LLE G++V G D + D + LK+ +E + +D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLN-DYYDVSLKQARLELLAQPGFQFHKID 60 Query: 59 LLELTNIMRVIEKIQPDEVYNLAAQSFVGVSFEQPILTAEIDAMGVLKLLEAIRTLKPDT 118 L + + + + V+ + V S E P A+ + G L +LE R K Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 119 KFYQASTSEMFGKVQEIPQTEKTPF-YPRSPYGVAKLFGHWITVNYRESFNIFACSGILF 177 Y AS+S ++G +++P + +P S Y K + Y + + Sbjct: 121 LLY-ASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL-------- 171 Query: 178 NHESPLRGIEFVTRKITYSLARIKYGLQDKLIL--------GNLDAKRDWGYAPEYVEGM 229 P G+ F T + + K +L KRD+ Y + E + Sbjct: 172 ----PATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 230 WLMLQQEKPDDYVLATGETHTVREFVEKAAEVAGFSLEWEGEG--------VDT--KGID 279 + V+ +T E AA +A + + G + + Sbjct: 228 IRLQD-------VIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG 280 Query: 280 RKSGKVIVEVSPEFYRPAEVDILIGNPEKAKKKLGWEPRTKFSQLVE 326 ++ K ++ + +P +V + + + +G+ P T V+ Sbjct: 281 IEAKKNMLPL-----QPGDVLETSADTKALYEVIGFTPETTVKDGVK 322
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 40.7 bits (95), Expect = 4e-05 Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 10/132 (7%) Query: 441 GYASDVITGNSAGTTILLGSGNDNLQFVDGANAGESNIIKLGAGDDKL-------VVTTN 493 G +D + G + + G G+D Q + A N++ G G+DKL ++ Sbjct: 779 GDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLA--KNVLFGGKGNDKLYGSEGADLLDGG 836 Query: 494 NGYTYVFGEDGNDDVVINAIDTNDLV-DLGAGTDTLTLDNTNASTAVLRGVENLVIKARD 552 G + G GND + + ++ D G D L+L + + + N +I + Sbjct: 837 EGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKG 896 Query: 553 NGQAVTINAADS 564 G ++I + Sbjct: 897 EGNVLSIGHKNG 908 Score = 32.2 bits (73), Expect = 0.016 Identities = 44/224 (19%), Positives = 70/224 (31%), Gaps = 23/224 (10%) Query: 961 VKTATIALGGGTDKLDL--TNLANLDANGVGAVINLSSFTQTVDGVSVDAGKIVEFDGTD 1018 VK +++G T+K +++ + NL S + + D +F Sbjct: 681 VKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIF 740 Query: 1019 DGTNNITDGYTITVNDVEEIVGTKGADIIFAANTGTTITSEAGADKIVLGAGADKVIIAA 1078 G + + I G G D ++ T++ G D++ G G DK+I Sbjct: 741 HGADG-----------DDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLI--- 786 Query: 1079 AGETGTITVADKDSSGDLSDGDTISGSFDVISNFEHGTDKLDISAVNDGTSTDTW-DSTN 1137 G G + D + + + G DKL S D D Sbjct: 787 -GVAGNNYLNGGDGDDEFQVQG--NSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLK 843 Query: 1138 GLDANAYQIVLGTWDETTNTFTVDSGSGTDTMVLFDDGLSDVAV 1181 G N L + D G D + L D DVA Sbjct: 844 GGYGNDIYRYLSGYGHHI---IDDDGGKEDKLSLADIDFRDVAF 884
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 32.0 bits (72), Expect = 0.004 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 15/73 (20%) Query: 289 YFEDVPISEEYKFYDKEENIPKIINKIKDCFENFEERYKDFNYYREV-----------IK 337 E VP + + ++K+ PK+I IKD N E + Y E+ K Sbjct: 131 RGEKVPFASRF-VFEKKRETPKLIINIKDYAINSE---QSKEVYYEIGKGISLDIISKDK 186 Query: 338 NELQKFLEDLKSI 350 + +FL +KS+ Sbjct: 187 SLDPEFLNLIKSL 199
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 34.5 bits (79), Expect = 8e-05 Identities = 13/52 (25%), Positives = 29/52 (55%), Gaps = 4/52 (7%) Query: 2 KKAFTLLELVIVLLIVSLTLTITLPTFF----NIEATSMENFENKLKTATNS 49 ++ FTLLE++++LL++ ++ + L F + A ++ FE +L+ Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQR 54
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.003 Identities = 11/50 (22%), Positives = 23/50 (46%), Gaps = 11/50 (22%) Query: 160 ASLSGRVVLARDFYYTGNTIVIDHGLGIYTLYAHLSKILVKEGQIVQAGQ 209 A+ +G++ + G + I + + +I+VKEG+ V+ G Sbjct: 84 ATANGKLTHS------GRSKEIKPIEN-----SIVKEIIVKEGESVRKGD 122
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 41.4 bits (97), Expect = 3e-07 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 33/137 (24%) Query: 1 MKERKGFTLVELAIVLVIIGLLLGAV---LKGQELIQNAKYKKLINDLQGLSAAVYTYY- 56 +++GFTL+E+ +V+VIIG+L V L G + + A +K ++D+ L A+ Y Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNK--EKADKQKAVSDIVALENALDMYKL 61 Query: 57 --DRY----------------KALPGDDPKAG-------DKWGSTYSNIINGDGNG--LI 89 Y L + K G D WG+ Y + G+ L+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 90 SGSPTSTTNTDESVQIW 106 S P T++ + W Sbjct: 122 SAGPDGEMGTEDDITNW 138
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 36.1 bits (83), Expect = 9e-05 Identities = 11/29 (37%), Positives = 21/29 (72%) Query: 1 MKRSGFTLIEMAIILVILGLILGIGMGTM 29 M++ GFTL+EM +IL+++G+ G+ + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAF 29
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 2e-04 Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 17 RKGFSLIEIAIVLVIVSILLGLGIRSCISGIETAKI 52 ++GF+L+EI +V+VI+ +L L + + + E A Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADK 42
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 40.7 bits (95), Expect = 2e-06 Identities = 25/129 (19%), Positives = 44/129 (34%) Query: 206 LKIDPDYAEAYAGIGFLYLKLNSPKAAVIAFRRAHSLNPKEISYSVNLAISLLGSGNIDE 265 +I D E + F + + A F+ L+ + + + L G D Sbjct: 29 NEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDL 88 Query: 266 AILEFQKLKNKYPFLPEIYYNEAVAYLKKGYYKKAIEDFEIFLELTKANKFYEDYREEVL 325 AI + P ++ A L+KG +A + EL +++ V Sbjct: 89 AIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRVS 148 Query: 326 KVLNQIKLI 334 +L IKL Sbjct: 149 SMLEAIKLK 157 Score = 36.4 bits (84), Expect = 5e-05 Identities = 18/86 (20%), Positives = 35/86 (40%), Gaps = 1/86 (1%) Query: 181 LYTYLGYAYTHLGRYTKALNAFKKALKIDPDYAEAYAGIGFLYLKLNSPKAAVIAFRRAH 240 LY+ + G+Y A F+ +D + + G+G + A+ ++ Sbjct: 39 LYSL-AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGA 97 Query: 241 SLNPKEISYSVNLAISLLGSGNIDEA 266 ++ KE + + A LL G + EA Sbjct: 98 IMDIKEPRFPFHAAECLLQKGELAEA 123
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 161 bits (409), Expect = 4e-45 Identities = 84/309 (27%), Positives = 139/309 (44%), Gaps = 39/309 (12%) Query: 211 DKTASYSVEPISGTVIVTAKPETLKKVKEFIDTINGISDRQVLIEAKIVEVKLDKRNELG 270 DK + +IVTA P+ + ++ I ++ I QVL+EA I EV+ LG Sbjct: 307 DKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLD-IRRPQVLVEAIIAEVQDADGLNLG 365 Query: 271 INW--KYLTFSNFLGSGGEYNTI---------------SFNSGAPEGKPFQLSIVKVNNT 313 I W K + F SG +T S S + N Sbjct: 366 IQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGN-- 423 Query: 314 FSGLLGILSQFGKVNVLSSPRILAMNGQPAMIKVGRDYLAIYRTQTTSTTSTSSQTATTL 373 ++ LL LS K ++L++P I+ ++ A VG++ T S T++ T+ Sbjct: 424 WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEV----PVLTGSQTTSGDNIFNTV 479 Query: 374 TTEEVTTNSILTEGVVLTIIPKIDDKGNIILNISPAISSLDSPLITGSTGETTDFINKVY 433 + V G+ L + P+I++ +++L I +SS + + T+ + Sbjct: 480 ERKTV--------GIKLKVKPQINEGDSVLLEIEQEVSS-----VADAASSTSSDLGAT- 525 Query: 434 SVNIRQLNTVVRVKNGQTVILGGLIAKSKSKEKEGVPILQDIPLLGNAFKSTSTISSKTE 493 N R +N V V +G+TV++GGL+ KS S + VP+L DIP++G F+STS SK Sbjct: 526 -FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRN 584 Query: 494 LVIMLTPYV 502 L++ + P V Sbjct: 585 LMLFIRPTV 593 Score = 43.8 bits (103), Expect = 1e-06 Identities = 27/182 (14%), Positives = 69/182 (37%), Gaps = 22/182 (12%) Query: 77 SFDNIDLKKALLALGKATGYNVIVPPDIEGKVSIE----LKGESLKDSLNSLLKPFGYSY 132 SF D+++ + + K VI+ P + G +++ L E S+L +G++ Sbjct: 33 SFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGFAV 92 Query: 133 KIDAKNIYVISKETKVFHINLPQTKRQFSSSIEASIGGSSEGTGSTTTTSTATMSIGNSY 192 + + + +K ++++ + ++ G G T ++ + Sbjct: 93 INMNNGVLKVVR-----------SKDAKTAAVPVA-SDAAPGIGDEVVTRVVPLTNVAAR 140 Query: 193 DLDIWNNIKSSIDVIVKNDKTASYSVEPISGTVIVTAKPETLKKVKEFIDTINGISDRQV 252 DL + + N S S +++T + +K++ ++ ++ DR V Sbjct: 141 DL------APLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSV 194 Query: 253 LI 254 + Sbjct: 195 VT 196
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 186 bits (475), Expect = 3e-57 Identities = 93/405 (22%), Positives = 186/405 (45%), Gaps = 5/405 (1%) Query: 1 MARYKVTFLSQDGIVNTEIVEAKNESELFSLFSERDVILLEYKKDWFSFLKEFSLLDLFQ 60 MA+Y L G EA + + L ER ++ L ++ K S + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 61 R-RKISKQELADFCFYFGRALDMGISVLEILEDIGKSSKNKYFRKVMETLRERVTAGSSL 119 R ++S +LA + + + E L+ + K S+ + ++M +R +V G SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SEAME-LTGAFPPELIGLVKVGESTDALPKVFLNYAEYLDWVISIEKEVKQALSYPIFVS 178 ++AM+ G+F +V GE++ L V A+Y + + ++QA+ YP ++ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 179 FIMVFTIAIMFGYIIPQIIPAITAMGLKEYPLPTKILLWSGKYVQIFWKEIVITPILLVI 238 + + ++I+ ++P+++ M + PL T++L+ V+ F +++ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMK-QALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 239 FFKLIMRYSIKARYIWDRLKISFPLIGDIFQKASLSRDMRALAEVYRSGGTILRALDIII 298 F++++R K R + R + PLIG I + + +R R L+ + S +L+A+ I Sbjct: 240 AFRVMLRQE-KRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISG 298 Query: 299 NHVEQNLYIKSIFQKVKENIMVGDMLSVAMERSGFFQSTIIRMIKLGEETGALDKSLLRL 358 + V N Y + + + G L A+E++ F + MI GE +G LD L R Sbjct: 299 D-VMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERA 357 Query: 359 AEIYEDDMRRKIQTMTVVIEPTLQLVLGGILGIVALGILLPVYNI 403 A+ + + ++ + EP L + + ++ + L IL P+ + Sbjct: 358 ADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQL 402
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 63.9 bits (155), Expect = 2e-12 Identities = 42/296 (14%), Positives = 106/296 (35%) Query: 202 RTLKSQAEKAKKFQELRNLEKELELKLLGLQLKNLRLEKEVSENSLKLLQEDRISLEREV 261 + + R + E+E L L+ +L + ++ L E+ + + ++ Sbjct: 42 AVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKL 101 Query: 262 SVLQVELEELRKELESITKEIEETSQELYEVEKSKKEASVKREFLQKEIKRLEEELKEKT 321 L E +++ + + + L S K + L+ E L + Sbjct: 102 RKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLE 161 Query: 322 FEREHKIRKIESIRKELQLIFQEESELQKKLEDLENREKEKERIVKELQQKRKAFEERLK 381 E + + +++ + E++ L+ + +LE + K K E Sbjct: 162 KALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA 221 Query: 382 ELKSSLSTTSTQISKLQLDMAREEERFKSLKNIKEKLPGEIEKLQKEKEYYLSYIERFVE 441 L + + + + + K+L+ K L +L+K E +++ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 442 KENSLKEKIEKLKEELENLKKEKKELLERLEVINSEVSEKREEIVSLRSKIESIEK 497 K +L+ + L+ E +L+ + + L + + ++ RE L ++ + +E+ Sbjct: 282 KIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Score = 59.7 bits (144), Expect = 5e-11 Identities = 44/326 (13%), Positives = 103/326 (31%), Gaps = 14/326 (4%) Query: 168 SFKEKKEETLQKLSEAEQNLESVRSVIDEVGKNLRTLKSQAEKAKKFQELRNLEKELELK 227 + +TL+K+ E E + + +L + + +L+ Sbjct: 43 VATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLR 102 Query: 228 LLGLQLKNLRLEKEVSENSLKLLQEDRISLEREVSVLQVELEELRKELESITKEIEETSQ 287 L + + E L++ + +++ L E ++ + + Sbjct: 103 KNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 162 Query: 288 ELYEVEKSKKEASVKREFLQKEIKRLEEELKEKTFEREHKIRKIESIRKELQLIFQEESE 347 L S K + L+ E LE E + K L+ + Sbjct: 163 ALEGAMNFSTADSAKIKTLEAEKAALEARQAE--------------LEKALEGAMNFSTA 208 Query: 348 LQKKLEDLENREKEKERIVKELQQKRKAFEERLKELKSSLSTTSTQISKLQLDMAREEER 407 K++ LE + +L++ + + + T + + L+ A E+ Sbjct: 209 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 268 Query: 408 FKSLKNIKEKLPGEIEKLQKEKEYYLSYIERFVEKENSLKEKIEKLKEELENLKKEKKEL 467 + N +I+ L+ EK + + L + L+ +L+ ++ KK+L Sbjct: 269 LEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQL 328 Query: 468 LERLEVINSEVSEKREEIVSLRSKIE 493 + + + SLR ++ Sbjct: 329 EAEHQKLEEQNKISEASRQSLRRDLD 354 Score = 57.8 bits (139), Expect = 2e-10 Identities = 64/366 (17%), Positives = 130/366 (35%), Gaps = 15/366 (4%) Query: 655 KNSLLEMEKELENLKEKLTREEKVLSCLQSKVLPIREEIDEKEEGIDSLKEAIQQKKMEL 714 SL E +++ L+ + EK L + +I E +L + L Sbjct: 105 DKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 164 Query: 715 FEVGSKIKEARRKLADLERKENELEDKLKRAVESINSYNSRKDIFLQKIESLSKKKDELV 774 + K+ LE ++ LE + +++ + KI++L +K L Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 775 KEIEKLEEDIKKLEANIGIEKEELSKYVSKKILLAEKLKNLKERKESKERFVRTLQKEIE 834 LE+ ++ + ++ ++K L + L++ E F +I+ Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 284 Query: 835 EIEKRIEKDEENLKKAAIGVKRAEEILGGVDESIDEIKKELQLLEERRGEITSMVKTKEE 894 +E E E ++ + ++++L E + ++ + + EE Sbjct: 285 TLEAEKAALEAEKAD-------LEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEE 337 Query: 895 ALKSKNKDLSEVQNKLKETEVAVARFNVKEEEIISKILELEKSVSDALEAALAA---GSE 951 K ++ L + A + + ++ LE + +S+A +L S Sbjct: 338 QNKISEASRQSLRRDLDASREAKKQLEAEHQK-----LEEQNKISEASRQSLRRDLDASR 392 Query: 952 EEVKKELINLKEKISKIGNVNFLAIEEYEKVKERYGFILEQEKDLIESIKNLREAIRKLD 1011 E K+ L+E SK+ + L E E K E + L K L+E + K Sbjct: 393 EAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQA 452 Query: 1012 EEIEKK 1017 EE+ K Sbjct: 453 EELAKL 458 Score = 52.0 bits (124), Expect = 1e-08 Identities = 43/285 (15%), Positives = 98/285 (34%), Gaps = 14/285 (4%) Query: 644 TGTGSIVGKFKKNSLLEMEKELENLKEKLTREEKVLSCLQSKVLPIREEIDEKEEGIDSL 703 T + + + + + E E LK K + L+ + EE+ +E + Sbjct: 45 TRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKN 104 Query: 704 KEAIQQKKMELFEVGSKIKEARRKLADLERKENELEDKLKRAVESINSYNSRKDIFLQKI 763 +++ +K ++ E+ ++ + + L K+K + +RK + + Sbjct: 105 DKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 164 Query: 764 ESLSKKKDELVKEIEKLEEDIKKLEANIGI--------------EKEELSKYVSKKILLA 809 E +I+ LE + LEA + ++ ++K LA Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 810 EKLKNLKERKESKERFVRTLQKEIEEIEKRIEKDEENLKKAAIGVKRAEEILGGVDESID 869 + +L++ E F +I+ +E E + ++ A I Sbjct: 225 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 284 Query: 870 EIKKELQLLEERRGEITSMVKTKEEALKSKNKDLSEVQNKLKETE 914 ++ E LE + ++ + +S +DL + K+ E Sbjct: 285 TLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLE 329 Score = 47.8 bits (113), Expect = 2e-07 Identities = 54/351 (15%), Positives = 119/351 (33%), Gaps = 17/351 (4%) Query: 144 QIDRVLKMKPQERRLLIDEAAGITSFKEKKEETLQKLSEAEQNLESVRSVIDEVGKNLRT 203 +++ L+ + + + K L +A + + + K L Sbjct: 124 DLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 183 Query: 204 LKSQAEKAKKFQELRNLEKELELKLLGLQLKNLRLEKEVSENSLKLLQEDRISLEREVSV 263 K+ E + E ++K L EK L++ + Sbjct: 184 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTA 243 Query: 264 LQVELEELRKELESIT-------KEIEETSQELYEVEKSKKEASVKREFLQKEIKRLEEE 316 +++ L E ++ K +E K ++ L+ E LE + Sbjct: 244 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 317 LKEKTFEREHKIRKIESIRKELQLIFQEESELQKKLEDLENREKEKERIVKELQQKRKAF 376 + R+ R +++ R+ + + E +L+++ + E + R + ++ +K Sbjct: 304 SQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL 363 Query: 377 EERLKELKSSLSTTSTQISKLQLDMAREEERFKSLKNIKEKLPGEIEKLQKEKEYYLSYI 436 E ++L+ + L+ D+ E K ++ E+ ++ L+K Sbjct: 364 EAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLN------- 416 Query: 437 ERFVEKENSLKEKIEKLKEELENLKKEKKELLERLEVINSEVSEKREEIVS 487 E E S K ++ E L+ E K L E+L E+++ R S Sbjct: 417 ---KELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKAS 464 Score = 47.8 bits (113), Expect = 2e-07 Identities = 46/284 (16%), Positives = 108/284 (38%) Query: 654 KKNSLLEMEKELENLKEKLTREEKVLSCLQSKVLPIREEIDEKEEGIDSLKEAIQQKKME 713 + +E E L + EK L + +I E +L+ + + Sbjct: 139 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 198 Query: 714 LFEVGSKIKEARRKLADLERKENELEDKLKRAVESINSYNSRKDIFLQKIESLSKKKDEL 773 L + K+ LE ++ L + +++ + KI++L +K L Sbjct: 199 LEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 774 VKEIEKLEEDIKKLEANIGIEKEELSKYVSKKILLAEKLKNLKERKESKERFVRTLQKEI 833 +LE+ ++ + ++ ++K L + +L+ + + ++L++++ Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDL 318 Query: 834 EEIEKRIEKDEENLKKAAIGVKRAEEILGGVDESIDEIKKELQLLEERRGEITSMVKTKE 893 + + ++ E +K K +E + +D ++ + LE ++ K E Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISE 378 Query: 894 EALKSKNKDLSEVQNKLKETEVAVARFNVKEEEIISKILELEKS 937 + +S +DL + K+ E A+ N K + ELE+S Sbjct: 379 ASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEES 422
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 8e-04 Identities = 12/46 (26%), Positives = 22/46 (47%), Gaps = 3/46 (6%) Query: 72 QEEKVEDTHEEQKEEVEAKEEKETQIIEKVEEEKTKEEPEKKKKEK 117 + ++T + +E E++E KVE EKT+E P+ + Sbjct: 1088 SGSETKETQTTETKETATVEKEEKA---KVETEKTQEVPKVTSQVS 1130 Score = 32.0 bits (72), Expect = 0.001 Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 7/80 (8%) Query: 43 KKALTELEEESLVKSESRRGKGLIITLLSQEEKVEDTHEEQKEEVEAKEEKETQIIEKVE 102 + A + V E++ + E + E +E + E KET +EK Sbjct: 1056 QDATETTAQNREVAKEAKSN---VKANTQTNEVAQSGSET--KETQTTETKETATVEK-- 1108 Query: 103 EEKTKEEPEKKKKEKKLSLQ 122 EEK K E EK ++ K++ Q Sbjct: 1109 EEKAKVETEKTQEVPKVTSQ 1128
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 3e-05 Identities = 10/28 (35%), Positives = 17/28 (60%) Query: 112 EIEAEVSGVVKKILVENGQPVEYGQPLF 139 EI+ + +VK+I+V+ G+ V G L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLL 125 Score = 29.4 bits (66), Expect = 0.005 Identities = 10/22 (45%), Positives = 12/22 (54%) Query: 88 FVKEGDFVEKGQTLCIIEALKV 109 VKEG+ V KG L + AL Sbjct: 111 IVKEGESVRKGDVLLKLTALGA 132
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 30.0 bits (67), Expect = 0.014 Identities = 16/50 (32%), Positives = 25/50 (50%) Query: 250 QGEIILDVGAAPGGKTTALSSLTIDKARIIAVDINKERMKLLKNNLKRLG 299 +G+I GAA G +L A I AVD N E+++ + ++LK Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEA 56
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.017 Identities = 14/81 (17%), Positives = 27/81 (33%), Gaps = 15/81 (18%) Query: 29 SGTQACKALKEEGYQVVLVNSNPATIMTDPDIADRTYIEPLTVEVLEKIIEKERPDALLP 88 + + + +V+ + M D + D L I+K RPD + Sbjct: 35 NAATLWRWIAAGDGDLVVTDVV----MPDENAFD-----------LLPRIKKARPDLPVL 79 Query: 89 TVGGQTALNLAVELYEAGILE 109 + Q A++ E G + Sbjct: 80 VMSAQNTFMTAIKASEKGAYD 100
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.8 bits (67), Expect = 0.003 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 12/72 (16%) Query: 30 GCFDILHAGHVDYLEKAKSLGDVLIVGMNSDSSIKRIKGEKRPIVSQDYR----AKVLIA 85 G FD + GH+D +E+ L D + V + + + K+P+ S R AK + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPN-------KQPMFSVQERLEQIAKAIAH 59 Query: 86 LKAVDYVFIFED 97 L V FE Sbjct: 60 LPNA-QVDSFEG 70
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 39.0 bits (91), Expect = 4e-06 Identities = 22/96 (22%), Positives = 39/96 (40%), Gaps = 12/96 (12%) Query: 1 MKALFGGSFNPVHIGHL-IVARDILETFGFEEIIFVPAYLQPLKDKLFLPPELRLELLRI 59 M A++ GSF+P+ GHL I+ R F+++ P K + + RLE + Sbjct: 1 MNAIYPGSFDPITFGHLDIIERGCRL---FDQVYVAVL-RNPNK-QPMFSVQERLEQIAK 55 Query: 60 SIEEEKGFSIWDYE------IRKKGISYTVDTLREF 89 +I + +E R++ + LR Sbjct: 56 AIAHLPNAQVDSFEGLTVNYARQRQAGAILRGLRVL 91
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 35.6 bits (82), Expect = 2e-06 Identities = 15/55 (27%), Positives = 29/55 (52%) Query: 4 ITFLKEVREELSRVTWPSKEEVIEATAGIVIFCIVVAVYFWALDFVFSELLKLII 58 + F +E R E+ +V WP+++E + T + V+++ W LD + L+ I Sbjct: 69 VAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVSFIT 123
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 89.1 bits (221), Expect = 3e-21 Identities = 70/320 (21%), Positives = 115/320 (35%), Gaps = 68/320 (21%) Query: 14 NVGTIGHVDHGKTTLTAAITHCLALQGKAQEV--AYDQIDKAPEERERGITIATAHVEYE 71 N+G + HVD GKTTLT ++ + + V + D ER+RGITI T ++ Sbjct: 5 NIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQ 64 Query: 72 SDKYHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHVLLARQVNVPYI 131 + +D PGH D++ + + +DGAIL++SA DG QTR R++ +P I Sbjct: 65 WENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTI 124 Query: 132 VVFLNKVD-----------------------------------------------MVDDE 144 F+NK+D + ++ Sbjct: 125 -FFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGND 183 Query: 145 ELLE-------LVELEVRELLNEYDFPGDEVPVIKGSALKALECTSPDCPDCQPIYELVN 197 +LLE L LE+ + + PV GSA + I L+ Sbjct: 184 DLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG-----------IDNLIE 232 Query: 198 ALDEYVPEPVREVDKPFLMPIEDVFSISGRGTVVTGRVERGKLTVGEEVEIVGLREEPIK 257 + + + R + R+ G L + + V I + I Sbjct: 233 VITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKIT 292 Query: 258 TVATGIEMFRKVLDEALPGD 277 + T I +D+A G+ Sbjct: 293 EMYTSINGELCKIDKAYSGE 312
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 28.9 bits (64), Expect = 0.037 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 15/83 (18%) Query: 34 NTKVTIGGELRERIEWYANDVGTGEGRDIYIPMRAKLKLKAELSDGVSAVFVPEAAFNAG 93 N ++I + R+ E +AN V T + EL + A F+PE A G Sbjct: 43 NIDISIKYDPRKDSEVFANRVITDD---------------IELLKKILAYFLPEDAILKG 87 Query: 94 SHFHGVGTNGLDLNKEVAQDSIN 116 H+ NG+ KE + S N Sbjct: 88 GHYDNQLQNGIKRVKEFLESSPN 110
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 38.7 bits (90), Expect = 3e-05 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 225 RHFRIGDCKLI-IGRNREENRFLRKHK-KEEDCVLWTPSIPGPTALLRCKKTPESSFLKI 282 HF D I +G+N +N +L + D T +IPG +++ S L Sbjct: 460 MHFISKDGIDIYVGKNNIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKNIMDIPESTLLE 519 Query: 283 AAEIVARYSDAKDRPSVEV 301 AA + A YS +++ +V V Sbjct: 520 AANLAAYYSKSQNSSNVPV 538
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 200 bits (510), Expect = 6e-58 Identities = 88/355 (24%), Positives = 156/355 (43%), Gaps = 27/355 (7%) Query: 303 RILPKTKIIKQELQEPTKTYIVNLNYANAEEIEKEIKELVKKL-------------DKRE 349 RI+ K + ++ T ++ L YA A ++ + + + + DK Sbjct: 251 RIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNI 310 Query: 350 RITVNKSTNSLLLTVTKKHYQEIMNLLKKLDKPMKQVIVKAKIVQISTSAAKDFGFGWLI 409 I + TN+L++T ++ ++ +LD QV+V+A I ++ + + G W Sbjct: 311 IIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWAN 370 Query: 410 --GGYNHMGTPPSSYITGSYGFGLGSNTGVLPFINETSYSSLYNIPVGESTLALGILNKS 467 G T G + G + ++ SS I G +L Sbjct: 371 KNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAML--- 427 Query: 468 QNLKVEIALKALQLDGNAKIVSSPEVLTLNNQEATIEQGIEIPYRE-STVASGGATTYTV 526 L AL I+++P ++TL+N EAT G E+P S SG TV Sbjct: 428 --------LTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTV 479 Query: 527 SFKRASLILKVKPHITNNNEIILDLEVRKDSPNYEHVALTGSNEPAIDTRNVKSRIKVAN 586 K + LKVKP I + ++L++E S + + +TR V + + V + Sbjct: 480 ERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGS 539 Query: 587 GNTIVIGGIYEKEKSKSKTGVPVISNIPLLGWLFKQESVKFTEKNLLIFITPKVV 641 G T+V+GG+ +K S + VP++ +IP++G LF+ S K +++NL++FI P V+ Sbjct: 540 GETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVI 594 Score = 53.4 bits (128), Expect = 2e-09 Identities = 26/166 (15%), Positives = 63/166 (37%), Gaps = 15/166 (9%) Query: 237 SLKFNNADVRSVVKAIANIAGINIVFDPEVKGTVSI---DFEKPVFWKDALEAVLTPLGL 293 S F D++ + ++ ++ DP V+GT+++ D + +VL G Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGF 90 Query: 294 TYKETENYMRILPKTKIIKQELQEPT-----------KTYIVNLNYANAEEIEKEIKELV 342 N + + ++K K T +V L A ++ +++L Sbjct: 91 AVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQLN 150 Query: 343 KKLDKRERITVNKSTNSLLLTVTKKHYQEIMNLLKKLDKPMKQVIV 388 + + +N LL+T + ++ +++++D + +V Sbjct: 151 DN-AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVV 195 Score = 31.8 bits (72), Expect = 0.008 Identities = 20/87 (22%), Positives = 43/87 (49%), Gaps = 8/87 (9%) Query: 323 IVNLNYANAEEIEKEIKELVKKLDKRE-------RITVNKSTNSLLLTVTKKHYQEIMNL 375 V L++A+A ++ K + EL K K + ++ TN++L++ Q I+ + Sbjct: 196 TVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAM 255 Query: 376 LKKLDKPMKQVIVKAKIVQISTSAAKD 402 +K+LD+ + K++ + + A D Sbjct: 256 IKQLDRQ-QATQGNTKVIYLKYAKASD 281
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 277 bits (710), Expect = 3e-92 Identities = 115/406 (28%), Positives = 220/406 (54%), Gaps = 8/406 (1%) Query: 1 MGVFTYKGYDKEGKERKGVIEASSRSGAISILKSQGIFPYEIKEEAIKKRNFSFSIF--- 57 M + Y+ D +GK+ +G EA S A +L+ +G+ P + E ++ + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 58 -KKALSVQELAVFFRTLATLLDAGIPLIEAIESLSENFKEDRKKIFMTKIVNNLREGKSL 116 K LS +LA+ R LATL+ A +PL EA++++++ ++ M + + + EG SL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 SESLKIA-GIKDPVIVSFVSSGEKGGTLVQSLEIIASILEKREELKSTIINALIYPVVLL 175 ++++K G + + + V++GE G L L +A E+R++++S I A+IYP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 176 VVAIGVVVFMMLSVIPKIVSIYTSMKISLPLSTKITLFISNGFINYYHFILIFFVFLTLF 235 VVAI VV ++ V+PK+V + MK +LPLST++ + +S+ + ++L+ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 236 FIFLEKRKKRE--FDKFKLRLPVFGKLFLYIELNRFFETLSSLLKAGIPIVDAMISATHT 293 F + +++KR F + L LP+ G++ + R+ TLS L + +P++ AM + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 294 VKNEYLKERLLLINNELKKGKSLATLFSKEIKELPTVALQLIKAGEQSGRLAELLSKVSK 353 + N+Y + RL L + +++G SL ++ P + +I +GE+SG L +L + + Sbjct: 301 MSNDYARHRLSLATDAVREGVSL-HKALEQTALFPPMMRHMIASGERSGELDSMLERAAD 359 Query: 354 FLRNEVEIYTKNLTSMLEPAIMIIIGLIVGFIVFSLLLPIVEISTI 399 E + EP +++ + +V FIV ++L PI++++T+ Sbjct: 360 NQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTL 405
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 29.4 bits (66), Expect = 0.028 Identities = 28/148 (18%), Positives = 55/148 (37%), Gaps = 25/148 (16%) Query: 39 LKSLFEELGFPFLEKLPQPQREVLEKVSPSFLRKERLIPLEEDENEVEVATDNPFNLEGI 98 LKSL E E L Q+E+++ V + +E N + PF Sbjct: 42 LKSLAIEKIIHVFENLTDEQKELIDTV-LTVQNREDAESFLLKINPYVI----PFQEVTA 96 Query: 99 KKIEWIFAKPVKIVVIPFDEVN----------------KFLMAKEETEEKEEVIDQYGED 142 + ++ +F K K+ + +E++ KF++AK +K + + G Sbjct: 97 QTLKKLFPKAKKLKLPDMEELDMKELSYLSWIDKGSSRKFIIAK---NDKNKFVGLQGTF 153 Query: 143 ILTLQEEAPTI-QLINDILMTAVRIKAS 169 ++ ++ ++ M V IK Sbjct: 154 QSLNKKSICSLCHGHEEVGMFLVEIKGD 181
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 353 bits (907), Expect = e-115 Identities = 167/617 (27%), Positives = 299/617 (48%), Gaps = 32/617 (5%) Query: 8 FTGISIAFSLPAYTKEPNKTVQINFDSVDIQDFTKVVSQAVRKNFIIPPSLKGKITIISP 67 F+ + F+ + + +F DIQ+F VS+ + K II PS++G IT+ S Sbjct: 10 FSLTLLIFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSY 69 Query: 68 KPIPKKELFNLYVAALDELGYQVVEYKDYV-KIVRNREATKESSIVKTGQI--DGGDRIL 124 + +++ + +++ LD G+ V+ + V K+VR+++A K +++ GD ++ Sbjct: 70 DMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDA-KTAAVPVASDAAPGIGDEVV 128 Query: 125 TYIIIPKHLEANSVRSLVRNLL--SPVGRVSIVRNSNAIVVTDKEKNVHRIETVVRRLDR 182 T ++ ++ A + L+R L + VG V SN +++T + + R+ T+V R+D Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 183 APMKMEIASFEIKNGKVEDVEKVLKVLLDKTFAFDIAKTVPLPGRDYYHFASDKRTNTLF 242 + + + DV K++ L T LPG + +D+RTN + Sbjct: 189 -AGDRSVVTVPLSWASAADVVKLVTELNKDT------SKSALPGSMVANVVADERTNAVL 241 Query: 243 VVGTQKVIREVQSLLPKLDKPLNVEDGNIHIIRLNYAFAEDMAKVLSSLF------KGTS 296 V G + + +++ +LD+ GN +I L YA A D+ +VL+ + K + Sbjct: 242 VSGEPNSRQRIIAMIKQLDRQ-QATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAA 300 Query: 297 RKSMGLTGEVKIVADKSSNSLIVLSSPSDFKVVKEVIDSVDIKRPQVFVEVQIVEMSMDK 356 + L + I A +N+LIV ++P ++ VI +DI+RPQV VE I E+ Sbjct: 301 KPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDAD 360 Query: 357 LLQLGVEWKFLSRG------NLVPFGGSLYG--NLPLQAGYPSASPGLLLGI--AKWRGD 406 L LG++W + G + +P ++ G S+ L Sbjct: 361 GLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFY 420 Query: 407 TPDIGLLLNAYAKEGGVNVIATPQILTLDNEEAEINISKVIPYSTGVKYDANNNPVISYD 466 + +LL A + +++ATP I+TLDN EA N+ + +P TG + + +N + + Sbjct: 421 QGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVE 480 Query: 467 YKDVGITLKITPHITASGEVRLKIYEKVEDVVGYANADQTA--PITSKREAKTTVDVQDG 524 K VGI LK+ P I V L+I ++V V A++ + + R V V G Sbjct: 481 RKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSG 540 Query: 525 QTLVIGGLIKSKKLTTIEKVPVLGNIPVLGNLFKKTGHQIEKTNLLVFITPRVVRSREEE 584 +T+V+GGL+ T +KVP+LG+IPV+G LF+ T ++ K NL++FI P V+R R+E Sbjct: 541 ETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEY 600 Query: 585 NELTNDKVNLYKENIQK 601 + ++ + + + K Sbjct: 601 RQASSGQYTAFNDAQSK 617
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 60.4 bits (146), Expect = 8e-13 Identities = 41/183 (22%), Positives = 87/183 (47%), Gaps = 15/183 (8%) Query: 89 TLKGTIICSQCSHSIVILKDKKTGKTLAVSEGKEIKGF--KVLKIYSDYVVLKKDGKEYI 146 +L G + S SI I+ K + + +E+ G+ K++ I D VVL+ G+ + Sbjct: 96 SLTGVMAGDDDSRSIAIIS--KDNEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQGRYEV 153 Query: 147 LKLFEKENKNSLSRLNTGFENFFQVKRKDIMNEIASGNFLRYINIVPNINPE---GLKVN 203 L L+ +E+ S G + + + + AS Y++ P +N G ++N Sbjct: 154 LGLYSQEDSGSDGV--PGAQV------NEQLQQRASTTMSDYVSFSPIMNDNKLQGYRLN 205 Query: 204 YVNRKSFIYKLGIKPGDVITSINDIHIKTPEDSFSAFEQLKNSDSITITVVRNGREVKLH 263 + Y++G++ D+ ++N + ++ E + A E++ + + T+TV R+G+ ++ Sbjct: 206 PGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIY 265 Query: 264 YEL 266 E Sbjct: 266 MEF 268
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.9 bits (69), Expect = 0.005 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 21/137 (15%) Query: 71 PKKYVPLPVRRALTNRLRQMRLEFEIREDNLRKLI----DELEKRIPETKSLLDKGSQIF 126 P++YVPL V+ + R++ L+F E L + D+ + + K+L + + Sbjct: 63 PRRYVPLQVKE----KRREIELQFRDAEKKLEASVQAELDKADAALGPAKNL----APLD 114 Query: 127 VMEGKESIVNQAIS------MISSAESTIKIAGNKPLFILECKGNLSKYMKRNVELAAIG 180 V+ +IV A+ +++ + T A N F+ + + R + Sbjct: 115 VINRSLTIVGNALQQKNQKLLLNQKKITSLGAKN---FLTRTAEEIGEQAVREGNINGPE 171 Query: 181 EFDQFCKDEIEKLGGKY 197 + +F E+E L Y Sbjct: 172 AYMRFLDREMEGLTAAY 188
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.031 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 109 bits (273), Expect = 2e-30 Identities = 30/123 (24%), Positives = 60/123 (48%), Gaps = 2/123 (1%) Query: 2 KVLIVDDERTIRETVKEILEDEGFEIFIEEAGSKVIGAIEKLKPDILILDLFLPGISGME 61 +L+ DD+ IR + + L G+++ I + + I D+++ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILKELHERGITQSLAVVIISGHGTVETSVKAMKLGAFDFLEKPIKYDKLIEVIEDAKKYL 121 +L + + L V+++S T T++KA + GA+D+L KP +LI +I A Sbjct: 65 LLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 122 SSE 124 Sbjct: 123 KRR 125 Score = 49.8 bits (119), Expect = 1e-09 Identities = 11/49 (22%), Positives = 22/49 (44%) Query: 138 PLKKAKEEFEKTYIKQVLKRFNGDLKKAATFMEIDISNLYRKLNKYGLN 186 + E E I L G+ KAA + ++ + L +K+ + G++ Sbjct: 428 LYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.9 bits (64), Expect = 0.049 Identities = 22/128 (17%), Positives = 40/128 (31%), Gaps = 21/128 (16%) Query: 324 PYTALFFYLFKLSYFKDLKRISELLSGKLELSVLEKKTENTEEEINSL--EDIYIKEVND 381 L Y F F+ ++ +G L + E+ ++ E+ Y + Sbjct: 44 SSQGLLGYYFSDLNFQAPMVVTSSTTGDLSIP---------SSELENIPSENQYFQSA-- 92 Query: 382 KKEFVEIIPKNRTAYELLKDRIGELEKRFGKRVKILEISNGN------GKK-EVKISQES 434 I K Y + + I + SN N G+ ++KI + Sbjct: 93 -IWSGFIKVKKSDEYTFATSADNHVTMWVDDQEVINKASNSNKIRLEKGRLYQIKIQYQR 151 Query: 435 EKKIDKLL 442 E +K L Sbjct: 152 ENPTEKGL 159
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.7 bits (66), Expect = 0.035 Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 9/85 (10%) Query: 6 PQVAFYPFMVLRDDYKCVRCKSCVDQCSFDATYYDEDLEMIVNRNENCVNCKRCEAFCPT 65 P Y + V RD K + T ++ED + +E CV K P Sbjct: 988 PTPTDYTYTVYRDGTKI--------KEGLTETTFEED-GVATGNHEYCVEVKYTAGVSPK 1038 Query: 66 DAIKVVKNPSTFHPDANWTEEAIRD 90 + + V NP+ F+P N T E + Sbjct: 1039 ECVNVTINPTQFNPVQNLTAEQAPN 1063
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.007 Identities = 17/106 (16%), Positives = 34/106 (32%), Gaps = 4/106 (3%) Query: 21 QEKTKKVVPQRNRENLINQIKNLNEKLKGKDKKIKELFREITELRNQIRELKKEKEAFES 80 + L + L + +K ++ T +I+ L+ EK A E+ Sbjct: 131 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 190 Query: 81 Q----TKEIERLDEYKRKIESLTQELAQLKGELAEKNKKIESLKTA 122 + K +E + + + L K LA + +E Sbjct: 191 RQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 236
>SECA#SecA protein signature. Length = 901 Score = 1143 bits (2959), Expect = 0.0 Identities = 436/859 (50%), Positives = 585/859 (68%), Gaps = 44/859 (5%) Query: 1 MLNAILTKIFGSKNEREIKKLKPIVEKINALEPEFEKKSKEDLRALTTKWKEEISKIEDD 60 ML +LTK+FGS+N+R +++++ +V INA+EPE EK S E+L+ T +++ + K E Sbjct: 1 MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEV- 59 Query: 61 KEKFKYMDKILPEAFAAVREAAKRTLGMRHYDVQLIGGMVLHQGKIAEMRTGEGKTLVAT 120 ++ ++PEAFA VREA+KR GMRH+DVQL+GGMVL++ IAEMRTGEGKTL AT Sbjct: 60 ------LENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTAT 113 Query: 121 LPVYLNALAGKGVHVVTVNDYLAKRDAEWMGPVYNYLGLSVGYLQNNMEKEQRKEMYSRD 180 LP YLNAL GKGVHVVTVNDYLA+RDAE P++ +LGL+VG M ++E Y+ D Sbjct: 114 LPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAAD 173 Query: 181 ITYGTNSEFGFDYLRDNMAFSKDEKVQRELFFAIVDEADSILIDEARTPLIISGPSEENV 240 ITYGTN+E+GFDYLRDNMAFS +E+VQR+L +A+VDE DSILIDEARTPLIISGP+E++ Sbjct: 174 ITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS 233 Query: 241 DVYYIADAIVRQLKK-----------DKHFEVDEKTKTAVLTDEGIREVEKIVSSMTGIK 289 ++Y + I+ L + + HF VDEK++ LT+ G+ +E+++ GI Sbjct: 234 EMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVK-EGIM 292 Query: 290 DF--NLYDPKFSDLLHAIIQSLRAHHLFKKDVDYVVKDGKVVIVDEFTGRIMPGRRWSDG 347 D +LY P L+H + +LRAH LF +DVDY+VKDG+V+IVDE TGR M GRRWSDG Sbjct: 293 DEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDG 352 Query: 348 LHQAVEAKEGVKIEAENQTLATITLQNYFRLYKKLAGMTGTAETEAAELKEIYGLDVVVI 407 LHQAVEAKEGV+I+ ENQTLA+IT QNYFRLY+KLAGMTGTA+TEA E IY LD VV+ Sbjct: 353 LHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVV 412 Query: 408 PTNKPVIRKDHPDLIFKTMKAKYNAVVKEIEENYKKGRPVLVGTNSIEASEYLSRLLKKK 467 PTN+P+IRKD PDL++ T K A++++I+E KG+PVLVGT SIE SE +S L K Sbjct: 413 PTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKA 472 Query: 468 GIPHQVLNAKHHEREAEIVAQAGRLGAVTIATNMAGRGTDILLGGNPEFLAKKELEKKGI 527 GI H VLNAK H EA IVAQAG AVTIATNMAGRGTDI+LGG+ + Sbjct: 473 GIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAAL------ 526 Query: 528 TPEKVGEEKYQEIYKETFERYKKITEEEKEKVKALGGLYIIGTERNESRRIDNQLRGRAG 587 + E E+ K + + V GGL+IIGTER+ESRRIDNQLRGR+G Sbjct: 527 ----------ENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSG 576 Query: 588 RQGDPGESRFFLSLEDNLLRLFGSDRIKKMMEMMNVPDDEPITHKMVSKALENAQRRVEQ 647 RQGD G SRF+LS+ED L+R+F SDR+ MM + + E I H V+KA+ NAQR+VE Sbjct: 577 RQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVES 636 Query: 648 QNFQIRKRLLEYDEVYNVQRKVIYDQRNKVLEGEDFKEDILYFMEEVAKEMVENYAPVNV 707 +NF IRK+LLEYD+V N QR+ IY QRN++L+ D E I E+V K ++ Y P Sbjct: 637 RNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQS 696 Query: 708 LPDEWDLSALKKALEARFGFEFNIPSTYDELMNLSIEDAHDDREKLVKLIYDRLVKEYEK 767 L + WD+ L++ L+ F + I D+ L E L + I + ++ Y++ Sbjct: 697 LEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPEL-------HEETLRERILAQSIEVYQR 749 Query: 768 MEKLVGEGQLREIERMIMLQTLDHYWRQHLLALDHIKESIGWRGYGQRDPIVEFKKEAFQ 827 E++VG +R E+ +MLQTLD W++HL A+D++++ I RGY Q+DP E+K+E+F Sbjct: 750 KEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFS 809 Query: 828 LFEELISNIQNGTVDGLFN 846 +F ++ +++ + L Sbjct: 810 MFAAMLESLKYEVISTLSK 828
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 77.7 bits (191), Expect = 9e-18 Identities = 35/198 (17%), Positives = 64/198 (32%), Gaps = 40/198 (20%) Query: 77 FRDFFFHFGIPFPFDNMPDEFKTKSLGSGFIVKVKNGWAYILTNNHVIDKATKIKVKLS- 135 + + P + SG +V G +LTN HV+D L Sbjct: 86 HYAPVTYIQVEAP--------TGTFIASGVVV----GKDTLLTNKHVVDATHGDPHALKA 133 Query: 136 -----------DGSIYKAKVVGKDPKTDIALIKIK-------IGNKKVPTVELGDSDNIK 177 +G ++ + D+A++K IG V + ++ + Sbjct: 134 FPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEV-VKPATMSNNAETQ 192 Query: 178 VGEFVIAVGNPYGLNWTVTHGIVSAKGRHGLGLNPIEN-FIQTDAAINPGNSGGPLCDIH 236 V + + G P + + ++ +Q D + GNSG P+ + Sbjct: 193 VNQNITVTGYPGDKPV-------ATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEK 245 Query: 237 GKVIGINTAIVRNAQGLG 254 +VIGI+ V N Sbjct: 246 NEVIGIHWGGVPNEFNGA 263
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 80.4 bits (198), Expect = 1e-19 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 19/135 (14%) Query: 95 VVTQEYVLLRLFNKVLFKPNSLELTPKAKEALDKVAEIIKKL-PGNYQVRIEGHTSIEEP 153 V T+ + L + VLF N L P+ + ALD++ + L P + V + G+T Sbjct: 210 VQTKHFTLK---SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGS 266 Query: 154 TKYLPYIHDDWDLSIRRATTVAKYLVSRGVNPKKIIAVGYGNTRPLYTWKNPILQAR--- 210 Y + LS RRA +V YL+S+G+ KI A G G + P+ ++ R Sbjct: 267 DAY------NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAAL 320 Query: 211 ------NRRVEIYLE 219 +RRVEI ++ Sbjct: 321 IDCLAPDRRVEIEVK 335
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 57.6 bits (139), Expect = 5e-12 Identities = 27/95 (28%), Positives = 41/95 (43%), Gaps = 16/95 (16%) Query: 147 KLKELELP---ITIEGHTDNVPIRSKIFPSNWELSAARAVSVLRLFIQCGYDPRKLSAAG 203 +L L+ + + G+TD + + N LS RA SV+ I G K+SA G Sbjct: 244 QLSNLDPKDGSVVVLGYTDRIGSDA----YNQGLSERRAQSVVDYLISKGIPADKISARG 299 Query: 204 CGPYRPIAPNTT---------PEGRAKNRRIEIVI 229 G P+ NT + A +RR+EI + Sbjct: 300 MGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.034 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>INTIMIN#Intimin signature. Length = 939 Score = 28.5 bits (63), Expect = 0.030 Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 4/77 (5%) Query: 1 MSVRVFFSAN--LKENQKEILKKTGFEPVSIPLIKTVPFEFSAEEVLKFSPNFTVISSKN 58 +++ +S N L ++ E++K + + +PL K +PFE+SA +L +P Sbjct: 82 INLSTIWSLNKHLYSSESEMMKAEPGQQIILPL-KKLPFEYSALPLLGSAP-LVAAGGVA 139 Query: 59 GVKHFFSKISPEKIRSS 75 G + +K+SP+ +S+ Sbjct: 140 GHTNKLTKMSPDVTKSN 156
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.3 bits (65), Expect = 0.015 Identities = 13/74 (17%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 42 ESLFKAYKEAKAEHKELLSKLEKCKKELELLKAKKAELEERYSTLNTEIEKLKREIAERE 101 + A + + LE + ELE + + +I+ L+ E A E Sbjct: 238 MNFSTADSAKIKTLEAEKAALEARQAELE---KALEGAMNFSTADSAKIKTLEAEKAALE 294 Query: 102 SLIAELQRLEKLSR 115 + A+L+ ++ Sbjct: 295 AEKADLEHQSQVLN 308
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.0 bits (57), Expect = 0.037 Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 2/50 (4%) Query: 41 KYKKLKAENEKLKEELKKCSDEKEAIKSEISSLE--SNIDELETTKTELE 88 KY KLK E E+L + +E + S ++++ N DE+E K EL Sbjct: 389 KYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKKELI 438
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 584 bits (1507), Expect = 0.0 Identities = 227/1099 (20%), Positives = 452/1099 (41%), Gaps = 100/1099 (9%) Query: 10 IAKRFITSKLTPLFL-LASMLIGLASIVLTPKEEEPQIVVPMVDVFIPYPGASAKEVERK 68 +A FI + L + M+ G +I+ P + P I P V V YPGA A+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 69 VSTEFERLIWEIKGIDYVYSIS-KPGMSLIIARFKVGENMEDSLVRLYNQLMSNLDKLPP 127 V+ E+ + I + Y+ S S G I F+ G + + + V++ N+L LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 128 GALKPLVKPMDINDVPIVSLTLWSNKRSPYELRELTK----ELCLQLKQVENVSKTWIIG 183 + + + ++ S+ +++ + L ++ V + G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPG-TTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 184 GDSKRYKILVDQDKLKNYNLSLLQIVQSIKSANVKLSAGKII------ENNTEFPVEAGE 237 +I +D D L Y L+ + ++ +K N +++AG++ + A Sbjct: 180 AQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 238 FIKTIDDLKNLVVTVY-DGKPVYLKDVAKVVNAPIDPENYVFIGFGPNSEKKGVGKNFIK 296 K ++ + + V DG V LKDVA+V + ENY + Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVE---LGGENY---------------NVIAR 280 Query: 297 ENGNLFPAVTIAIAKKRGTNAVTVAKEILNKFEDVKKKILPSDVHVTITRNYGKTAQDKF 356 NG PA + I G NA+ AK I K +++ P + V + Q Sbjct: 281 INGK--PAAGLGIKLATGANALDTAKAIKAKLAELQP-FFPQGMKVLYPYDTTPFVQLSI 337 Query: 357 DELMFHLGVAIFAVVIFIGLTLG-IKEAFVVSIAIPTTLALTLFVDLLTGYTLNRVTLFA 415 E++ L AI V + + L L ++ + +IA+P L T + GY++N +T+F Sbjct: 338 HEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFG 397 Query: 416 LIFTLGLLVDDAIVVVENIHRHLKLKKLPPLQAAIYAVAEVGNPTILATFTVIAALLPMA 475 ++ +GLLVDDAIVVVEN+ R + KLPP +A +++++ + + A +PMA Sbjct: 398 MVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMA 457 Query: 476 FVSGLMGPYMRPIPVNASIAMFFSLIVAFVISPWAAYYLLRKETEKEKKKFELEKTITYR 535 F G G R + AM S++VA +++P LL+ + + + Sbjct: 458 FFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNT 517 Query: 536 VYNKLVR---PLLDSSLKRWAFLFGVFLLMIGSVMMFYTKAVVVKLLPFDNKSEFQVVVD 592 ++ V + L ++ L++ +++ + + + LP +++ F ++ Sbjct: 518 TFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLR-LPSSFLPEEDQGVFLTMIQ 576 Query: 593 MPEGTSSEETARVTKAIADYLSKIPEVTDYELYIGTSSPFDFNGLVRHYYLRKGGNVADI 652 +P G + E T +V + DY K + ++ T + F F+G + N Sbjct: 577 LPAGATQERTQKVLDQVTDYYLKNEKANVESVF--TVNGFSFSGQAQ--------NAGMA 626 Query: 653 RVNLIDKGERKRQSHDIAREERPKIQAVARSVNPKANVKIVEVPPGPPVLSTLVA----- 707 V+L ER + A+ K V P ++ A Sbjct: 627 FVSLKPWEERNGDE-----NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDF 681 Query: 708 ---EIYGKDDDVRRKIAKQVAEIFRKTPG-VVDVDTLVDADHYKYEVKIDREKARKSGIT 763 + G D + Q+ + + P +V V D ++++++D+EKA+ G++ Sbjct: 682 ELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVS 741 Query: 764 EEQVVQTVNIALKGASISVAHTDYDSEAVSIFIRLPRKQREGIDDILNLSVLNKEGNLIP 823 + QT++ AL G ++ ++++ K R +D+ L V + G ++P Sbjct: 742 LSDINQTISTALGGTYVND--FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVP 799 Query: 824 LREIATIVKVPAEKTIYHKNLHPVSYVIGDVAGKYEAPIYPILAINKYLSEHPLPEGYKL 883 T V + N P + G+ A + +A+ + L+ LP G Sbjct: 800 FSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG--DAMALMENLASK-LPAGIGY 856 Query: 884 KYTFIPPSMPKDDFKPMMKWDGEWQITYETFRDMGAAFIVALIFIYLLIVGQFQSFIIPI 943 +T G + A ++ + ++L + ++S+ IP+ Sbjct: 857 DWT------------------GMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 944 IIMIPIPLTMIGIIPGHWLMTKLLGKTTYFTATSMIGFIALAGIVVRNSIILMDFIL-MK 1002 +M+ +PL ++G++ L M+G + G+ +N+I++++F + Sbjct: 899 SVMLVVPLGIVGVLLAATLF------NQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 1003 KREGAPLKDSIIEAGAVRFRPIVLTAAAAIVGAAVILLDP-----IFQGLAVSLLFGVFA 1057 ++EG + ++ + A +R RPI++T+ A I+G + + + + ++ G+ + Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 1058 STTLTLIVIPVIYYMLEKK 1076 +T L + +PV + ++ + Sbjct: 1013 ATLLAIFFVPVFFVVIRRC 1031 Score = 70.6 bits (173), Expect = 3e-14 Identities = 65/440 (14%), Positives = 154/440 (35%), Gaps = 70/440 (15%) Query: 668 DIAREE-RPKIQAVARSVNPKANVKIVEVPPGPPVLSTLVAEIYGKDD----DVRRKIAK 722 DIA+ + + K+Q + + + + V + + D+ +A Sbjct: 101 DIAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS 160 Query: 723 QVAEIFRKTPGVVDVDTLVDADHYKYEVKIDREKARKSGITEEQVVQTV---NIALKGAS 779 V + + GV DV L A Y + +D + K +T V+ + N + Sbjct: 161 NVKDTLSRLNGVGDV-QLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ 218 Query: 780 ISVAHTDYDSEA-VSIFIRLPRKQREGIDDILNLSVLNKEGNLIPLREIATIVKVPAEKT 838 + + SI + K E + +N +G+++ L+++A + Sbjct: 219 LGGTPALPGQQLNASIIAQTRFKNPEEFGKVT--LRVNSDGSVVRLKDVARVELGGENYN 276 Query: 839 IYHK-NLHPVSYVIGDVAGKYEAPIYPILAINKYLSEHPLP--EGYKLKYTFIPPSMPKD 895 + + N P + L I + L + K K + P P+ Sbjct: 277 VIARINGKPAA----------------GLGIKLATGANALDTAKAIKAKLAELQPFFPQG 320 Query: 896 DFKPMMKWDGEWQITYETFRDMGAAF----------IVALIFIYLLIVGQFQSFIIPIII 945 MK Y+T + + I+ + + L + ++ +IP I Sbjct: 321 -----MKVL----YPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIA 371 Query: 946 MIPIPLTMIGIIPGHWLMTKLLGKTTYFTATSM-IGFIALA-GIVVRNSIILMDFILMKK 1003 +P+ ++G + G ++ ++ + + LA G++V ++I++++ + Sbjct: 372 ---VPVVLLGTF----AILAAFG----YSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 1004 REGAPLKDSIIEAGAVRFRPIVLTAAAAIVGAAVILL------DPIFQGLAVSLLFGVFA 1057 E E + + ++ A + + + I++ +++++ + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 1058 STTLTLIVIPVIYYMLEKKN 1077 S + LI+ P + L K Sbjct: 481 SVLVALILTPALCATLLKPV 500
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.1 bits (130), Expect = 4e-10 Identities = 41/253 (16%), Positives = 78/253 (30%), Gaps = 51/253 (20%) Query: 80 DRVRKGEVLAVIDSSEIKPDVKKAKAALKEVEAALREIDKAVEEVKALKSAAKANYNFTQ 139 V + EVL + S IK + + E L + V A + + + Sbjct: 177 QNVSEEEVLRLT--SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 140 RTYQRFKRLYESEAVSKQKFDEIKTKLEEAKSKLKAIEAKEAQL---------------- 183 F L +A++K E + K EA ++L+ +++ Q+ Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQ 294 Query: 184 ------LEKKKGLLAKKEQVKAELSKASAFLSYTYLKSPIDGIVLKKLVDNGNLIFPQTS 237 L+K + + EL+K + +++P+ V + + Sbjct: 295 LFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV------QQLKVHTEGG 348 Query: 238 VFQLG---------SYPLRVHAFIDSSYAGKVKVGETLPVKLK--------NKVIMGKVT 280 V L V A + + G + VG +K ++GKV Sbjct: 349 VVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG--QNAIIKVEAFPYTRYGYLVGKVK 406 Query: 281 EV--DKSADPASH 291 + D D Sbjct: 407 NINLDAIEDQRLG 419 Score = 51.4 bits (123), Expect = 3e-09 Identities = 31/170 (18%), Positives = 72/170 (42%), Gaps = 10/170 (5%) Query: 42 TIKIEKKDSFSGTVIPDKQI-MVSPKVVGYLKEIKVKVGDRVRKGEVLAVIDSSEIKPDV 100 ++E + +G + + + P +KEI VK G+ VRKG+VL + + + D Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADT 136 Query: 101 KKAKAAL---KEVEAALREIDKAVEEVKALKSAAKANYNFTQRTYQRFKRLYESEAVSKQ 157 K +++L + + + + +++E K + F + + RL ++ K+ Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL---TSLIKE 193 Query: 158 KFDEIKTKLEEAKSKLKAIEAKEAQLLEKKKGLLAKKEQVKAELSKASAF 207 +F + + + + ++ K A+ L + + + E S+ F Sbjct: 194 QFSTWQNQKYQKEL---NLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 187 bits (476), Expect = 1e-63 Identities = 65/157 (41%), Positives = 104/157 (66%), Gaps = 3/157 (1%) Query: 4 KAIYPGTFDPVTLGHIDIVRRGIELFQELIIGIAENPKKEPLFTLEERKKMFEESLKEVG 63 AIYPG+FDP+T GH+DI+ RG LF ++ + + NP K+P+F+++ER + +++ + Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 LYEKVKVKTFNSLLVEFAKKEGAVAILRGIRIISDMDHEFTMASINRKLYPEIETVFLMP 123 +V +F L V +A++ A AILRG+R++SD + E MA+ N+ L ++ETVFL Sbjct: 62 ---NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTT 118 Query: 124 SDEYAYLSSSAVREIAFYGGDVSQFVTKCVETKLKEK 160 S EY++LSSS V+E+A +GG+V FV V L ++ Sbjct: 119 STEYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQ 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.025 Identities = 7/30 (23%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 57 GNARKTCRYFGISPTTFYKWKKRYDKYGIE 86 GN K G++ T K+ + G+ Sbjct: 450 GNQIKAADLLGLNRNTLR---KKIRELGVS 476
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 32.8 bits (75), Expect = 0.001 Identities = 16/40 (40%), Positives = 22/40 (55%) Query: 203 VVFTGGGALNPLLVKLVSEKLGMEVSVPKQPQLVGAFGAA 242 +V TGGGAL L +L+ E+ G+ V V + P A G Sbjct: 291 MVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGG 330
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 27.0 bits (59), Expect = 0.031 Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 8/99 (8%) Query: 48 DIEEKKKEALLEFSKKLAEKVAFVDIKVVAENEELEIFVIVLDEFESLKPVMETAL---- 103 D+ +K + +LE +L ++ F DI +V E E+ + +E S+ E Sbjct: 84 DLLKKIPKDVLEIYSELGGEIYFTDIDLV---EHKELQDLSEEEKNSMNSRGEKVPFASR 140 Query: 104 SLYEDLGVYLPVQVISKRKLLRWKEQRNKVYDLIKKGVS 142 ++E P +I+ + EQ +VY I KG+S Sbjct: 141 FVFEKKR-ETPKLIINIKDYAINSEQSKEVYYEIGKGIS 178
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 30.9 bits (70), Expect = 0.003 Identities = 12/49 (24%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 1 MKCCIVGKFESFHKGHQSLIKEAKEKCNEVFI-ISIKKWKDGIFSDKER 48 M G F+ GH +I+ ++V++ + K +FS +ER Sbjct: 1 MNAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQER 49
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.8 bits (62), Expect = 0.038 Identities = 11/22 (50%), Positives = 13/22 (59%) Query: 37 PSFNVDPQKDEVLVDGELVEYE 58 P VDP+ EV DGEL+ E Sbjct: 535 PHIEVDPETYEVRADGELLTCE 556
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.4 bits (71), Expect = 7e-04 Identities = 11/23 (47%), Positives = 18/23 (78%) Query: 4 KNEGFTLIELLIVITVISILFSI 26 K GFTL+E+++VI +I +L S+ Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASL 28
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.4 bits (128), Expect = 6e-12 Identities = 26/78 (33%), Positives = 46/78 (58%), Gaps = 2/78 (2%) Query: 7 LRSKELRKGFTLVELLIVIAIIAILAAIAVPQFSKYKEKAYIAAMKSDAHNVIAAEEAYF 66 +R+ + ++GFTL+E+++VI II +LA++ VP KEKA SD + A + Y Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 67 AENDNY--TDNGTKLGIK 82 +N +Y T+ G + ++ Sbjct: 61 LDNHHYPTTNQGLESLVE 78
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.003 Identities = 19/134 (14%), Positives = 44/134 (32%), Gaps = 11/134 (8%) Query: 46 KELKGIEEKLNKLKEEIPKLRVSIDNIRQDLSKVEEKF----PLIEK------SIKETKS 95 + E L+K + E + I+ + + L+ K ++ E ++ Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 96 YALKLNQNSEQNTEKKLLKLKEEISLQFDSVSKEISTIKKEINASKEDERQKLKELEEKI 155 ++ + +L +++ EI + K EI + L ++ Sbjct: 260 KYVEAVNELRV-YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 156 REIEERLSNLRIPS 169 + EER I + Sbjct: 319 AKNEERQQASVIRA 332
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 29.9 bits (67), Expect = 0.025 Identities = 14/53 (26%), Positives = 29/53 (54%) Query: 413 KGLVQISDESALKEIIKKVLGNNEKAVKQYKEGNDKQKQKAVKFLIGQVMKET 465 K LV++ + +++ ++K+ E+ K +G+ KQ+Q A + +KET Sbjct: 379 KDLVKLQRHAGIRKAMEKLAAQQEEDAKNQGKGDCKQQQGASEKSKEGKVKET 431
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 32.2 bits (73), Expect = 0.007 Identities = 12/72 (16%), Positives = 36/72 (50%), Gaps = 7/72 (9%) Query: 161 KKKFFAMVERIKELLPQFEKLQKQYNRNKKNLQLKREYLKTWARINFL------LRQLPL 214 K ++ +M +++ L P+ + ++++ +K+ + + L ++N L L Q+P+ Sbjct: 374 KAQYTSM-AKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPI 432 Query: 215 SYSIYETMADDI 226 ++Y + + Sbjct: 433 FLALYYMLMGSV 444
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.9 bits (67), Expect = 0.033 Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 3/65 (4%) Query: 110 QIEEAGYRAASYFHSKLSSILSYLKERGISEKEAKKFLIGYAPQGYSKE---LNLNPKLA 166 ++ A AA+ HS S LK+ + A LI P+ Y + LN + A Sbjct: 12 TLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTA 71 Query: 167 KELGL 171 ELG+ Sbjct: 72 DELGI 76
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 3/129 (2%) Query: 3 RIAVVEDDISIGNLLKRILSKEGFYVKVYSTGEALINELFEYGKEYDLIILDVMLPGMNG 62 I V +DD +I +L + LS+ G+ V++ S L + + DL++ DV++P N Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA--GDGDLVVTDVVMPDENA 62 Query: 63 VETCRFLRERKVKVPILMLTALSEEDDKVIGLDSGADDYVTKPFGVKELLARI-RALLRR 121 + +++ + +P+L+++A + + + GA DY+ KPF + EL+ I RAL Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 122 KETISGTQS 130 K S + Sbjct: 123 KRRPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 7e-07 Identities = 26/125 (20%), Positives = 50/125 (40%), Gaps = 24/125 (19%) Query: 197 LKVEIDLQDIVVPCEKILVEQM-IRNLVDNAIKF-----TKKGKIEITLKRNNKEVVILI 250 L+ E + + V M ++ LV+N IK + GKI + ++N V + + Sbjct: 240 LQFENQINP---AIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 251 KDTGKGIKEELKKHIFEKYVKSPESNGQGIGLSIVKE-IINYHNWKIDFQSEEEKG-TTF 308 ++TG + K+ G GL V+E + + + + E++G Sbjct: 297 ENTGSLALKNTKE-------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA 343 Query: 309 SIKIP 313 + IP Sbjct: 344 MVLIP 348
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.021 Identities = 13/79 (16%), Positives = 26/79 (32%), Gaps = 14/79 (17%) Query: 51 EGRKPVKIEVPAAKGTP-----------LVSKDKKIKIEGKAYIHYDVDLKNGN---HNN 96 E R P+ I PA + L+ ++K+ + H+ VD K+ Sbjct: 218 EARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTER 277 Query: 97 AFKITRNYFEVRGYFNDKD 115 + G ++ + Sbjct: 278 GLVLIEELLVKEGIMDEGE 296
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 332 bits (854), Expect = e-115 Identities = 93/359 (25%), Positives = 165/359 (45%), Gaps = 22/359 (6%) Query: 4 WAEIHLNRLFHNYREIKKISGRKKIFAVVKANAYGHGSVRISKFLEDKTDVSGFAVATFE 63 A + L L N +++ + ++++VVKANAYGHG RI + GFA+ E Sbjct: 6 QASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGAT---DGFALLNLE 62 Query: 64 EGKELREARIRREILVMASHLEEGYKE-AVDYRLTPVIFDFEGLKLVKELD----IPFHV 118 E LRE + IL++ E +RLT + LK ++ + ++ Sbjct: 63 EAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYL 122 Query: 119 KIDTGMGRLGFLENEWNELLSELKYSK---VEGIMSHFSSADEDLDFTKEQFKKFYSFAS 175 K+++GM RLGF + + +L+ +MSHF+ A+ D + A Sbjct: 123 KVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEH-PDGISGAMARIEQAAE 181 Query: 176 ELKQLKPEIKIHIDNSAAIPIKFDSILTHCRVGIALYGSKPYPDY----PLNLKQVMEVK 231 L+ + + NSAA ++ R GI LYG+ P + L+ VM + Sbjct: 182 GLECRR-----SLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLS 236 Query: 232 AKVISIKELPSEFPISYSKTYKTSKQEKVAVISFGYADGLLRSLSNKGEVLINGRRCPIR 291 +++I ++ L + + Y Y ++++ +++ GYADG R VL++G R Sbjct: 237 SEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTV 296 Query: 292 GRICMDMTIVSI-EGLKVRKGDTAIISGEKLTFEEIAEKAGTIPYEIMCDISPRVKRIY 349 G + MDM V + + G + G+++ +++A AGT+ YE+MC ++ RV + Sbjct: 297 GTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVT 355
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 33.2 bits (76), Expect = 0.002 Identities = 8/29 (27%), Positives = 12/29 (41%), Gaps = 1/29 (3%) Query: 30 EICKEIKKT-AKIPGFRPGKAPINIIKKY 57 E+ +KK IPG R G+ + Sbjct: 342 EVADNMKKYGGFIPGIRAGRPTAEYLSYV 370
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 26.8 bits (59), Expect = 0.043 Identities = 11/42 (26%), Positives = 18/42 (42%) Query: 7 IPENLLRKRVRELAEEISKQFGNSSITVVSVLKGATVFTADL 48 + +R+ SKQ G S I V TV+++D+ Sbjct: 22 QVIEMNNSSLRDFVTWYSKQTGESVIVSPDVKGTVTVYSSDV 63
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.0 bits (83), Expect = 4e-04 Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 18/82 (21%) Query: 193 VLLAGAPGTGKTLLAKAI---AGEANVPFLSVS---------GSEF--VEMFVGVGASRV 238 +++ G GTGK L+A+A+ N PF++++ SE E GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 239 RD-LFEQAKRHAPCIVFIDEID 259 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 32.2 bits (73), Expect = 0.001 Identities = 16/67 (23%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 54 IGLSYLNIGEIPLALNYLFKAKELKPNDPKIYNAIGVAFIQRGELDRAEKYLRKAIKM-- 111 +G +G+ LA++ + +P+ +Q+GEL AE L A ++ Sbjct: 76 LGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIA 135 Query: 112 -KPNFSE 117 K F E Sbjct: 136 DKTEFKE 142 Score = 28.7 bits (64), Expect = 0.015 Identities = 12/80 (15%), Positives = 27/80 (33%), Gaps = 4/80 (5%) Query: 192 LAKILENEGKIEEAQEIYLRLVSLYPKVQYPYYRLALIYLKKKKIQHAKALL----KKCI 247 L + G+ + A Y + K + A L+K ++ A++ L + Sbjct: 76 LGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIA 135 Query: 248 KLNPDSDIGIKAKIKLEELD 267 ++ + LE + Sbjct: 136 DKTEFKELSTRVSSMLEAIK 155
>PF01206#SirA family protein Length = 76 Score = 69.0 bits (169), Expect = 5e-18 Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 2/69 (2%) Query: 5 IDCKGLACPIPVMKTKEALESIENG-TVTVIVDNKASRENVKRFAEKLGCK-VKVEEKKG 62 +D GL CP+P++K K+ L ++ G + V+ + S ++ + F+++ G + ++ +E+ G Sbjct: 8 LDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEEDG 67 Query: 63 LYYLTITKG 71 Y+ + + Sbjct: 68 TYHFRLKRA 76
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.3 bits (237), Expect = 6e-25 Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 1/123 (0%) Query: 2 KILLVEDEKLLANTLKKGLEEEGYIVDVAYDGEEGFFLGRCYGYDVIILDVMLPKLDGME 61 IL+ +D+ + L + L GY V + + + D+++ DV++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLLKLREEGVKTPILMLTAKDSVEDKVKGLDSGADDYLTKPFSYDELLARI-RALLRRKS 120 LL ++++ P+L+++A+++ +K + GA DYL KPF EL+ I RAL K Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 ESK 123 Sbjct: 125 RPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 44.1 bits (104), Expect = 7e-07 Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 27/107 (25%) Query: 361 LLIQLFVNILENAIKYNI----YGGSVNIDVKNTEQELRVSISDTGVGIPEKEINRVFEK 416 +L+Q V EN IK+ I GG + + + + + +TG + Sbjct: 258 MLVQTLV---ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT------- 307 Query: 417 FYTVKECDLKEPGTGIGLSIVKE-IAELH--RASLKIESKLNKGTTI 460 + TG GL V+E + L+ A +K+ K K + Sbjct: 308 ----------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.002 Identities = 26/144 (18%), Positives = 52/144 (36%), Gaps = 23/144 (15%) Query: 50 DITVEVPGQIDLS-NVCAITSKTEGYIT-TYVGKGDSVKKGKVIAEI------------Q 95 +I G++ S I + V +G+SV+KG V+ ++ Q Sbjct: 81 EIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQ 140 Query: 96 NEILKTKVLSLKNKISLVKGELLNFN-------KKLKNYQELFQLGLIS--KNDLVNLKN 146 + +L+ ++ + +I EL +N E L L S K +N Sbjct: 141 SSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 147 TILNKKIELENLQHQLRILQFQEN 170 K++ L+ + + + + N Sbjct: 201 QKYQKELNLDKKRAERLTVLARIN 224 Score = 29.8 bits (67), Expect = 0.016 Identities = 21/158 (13%), Positives = 51/158 (32%), Gaps = 45/158 (28%) Query: 86 KKGKVIAEIQNEILKTKVLSLKNKISLVKGELLNFNKKLKNYQELFQLGLISKNDLVNLK 145 + K E+ + + + L++ +I+ + +L ++ L I+K+ ++ + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE 258 Query: 146 NT---------------------ILNKKIELEN----------------------LQHQL 162 N IL+ K E + L +L Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Query: 163 RILQFQENYSKIISPCNGYV--LEIVPNKGYIKIGTQI 198 + ++ S I +P + V L++ G + + Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 461 bits (1188), Expect = e-148 Identities = 208/1040 (20%), Positives = 437/1040 (42%), Gaps = 48/1040 (4%) Query: 8 LFILQRKFAISLTLLILSLVGYLVSKDIPRGVFPNVFFPRIEVTIENGFVPVEQMLSEVT 67 FI + FA L ++++ + G L +P +P + P + V+ + + VT Sbjct: 4 FFIRRPIFAWVLAIILM-MAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 68 KPAEESLKTVQDAEKIVSKT-SVGSTEINIYFDWKINPYLAYQLVQARVAELKNRLPSTA 126 + E+++ + + + S + S GS I + F +P +A VQ ++ LP Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 127 NVV-VRQATPSIYPIAIYAICSNSLPRDK--LTEILYYQLKPLFLSIKGVYDIEIKAPEW 183 + S + + S++ + +++ + +K + GV D+++ + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ- 181 Query: 184 EEYHVIVDLKKLANYNIDIGKVVSILREQT------KIKFLGKLDSPHKQYIISLYQKSK 237 + +D L Y + V++ L+ Q ++ L I + K Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 238 DIYKLLKIKIPVS-NSKFISLSDIAIIVKSHTPVKSISAFSGYKNAVVFNLLRQPNANSV 296 + + K+ + V+ + + L D+A + I+ +G K A + AN++ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING-KPAAGLGIKLATGANAL 300 Query: 297 EVVKNVDELLGKINASLKKQGIIIKKSYDSTLFIEEAIKSVRDAILLGSVIAVFIIYLFL 356 + K + L ++ QG+ + YD+T F++ +I V + ++ ++YLFL Sbjct: 301 DTAKAIKAKLAELQPFFP-QGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 357 RKVKLSLATLLTIPVIFFITIIGIKITKLDFNLFSLGGLAAAIGGLIDHIIIVTENIERH 416 + ++ +L + +PV+ T + N ++ G+ AIG L+D I+V EN+ER Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 417 LRKGK-DKLTAVIEGSKEIIPIMTVATLISIIVFIPLLLVSGIVGVFFKQLALVLVATYI 475 + + K A + +I + ++ VFIP+ G G ++Q ++ +V+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 476 ISQILAIFFVPIVAYILL-----PQKEEKK------VDLIERLKEKYANFLRRALKYDYL 524 +S ++A+ P + LL E K + Y N + + L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 525 SVPLIIIGILTTFVLYKALPSTFLPKWDEGNLVVDFSFSPGTSLEEAYKEAMEIGKII-- 582 + + + + VL+ LPS+FLP+ D+G + G + E K ++ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 583 NSIPEVENWTLRIGTSLGHIVTQPSKGDFLVVLK-----SNRKRSIFQIKEELRAKVLS- 636 N VE+ G S + G V LK + + S + + ++ Sbjct: 600 NEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 637 RFPNLQEFDLPQVLEDRLGDIMGAEAPISIILYGSDPEKLIKTGQYLRDILRKQPL-LEE 695 R + F++P ++E LG G I G + L + L + + P L Sbjct: 658 RDGFVIPFNMPAIVE--LGTATGF-DFELIDQAGLGHDALTQARNQLLGMAAQHPASLVS 714 Query: 696 VNLKTNYVSPSIQISVKPDAEALYGITVNDIYNQLYSIYWGKVIGNIMQGEKI--INIRL 753 V + ++ V + G++++DI + + G + + + ++ + ++ Sbjct: 715 VRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQA 774 Query: 754 LSSQKKSFFEIQKLKVYSPKLGKLIPISYVVDISFKDKVPEITHYNLSPVSVITLRF-KG 812 + + ++ KL V S G+++P S + P + YN P I G Sbjct: 775 DAKFRMLPEDVDKLYVRSAN-GEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG 833 Query: 813 NNMSKAVEIIQKVIKEAKISSSISPVISGFYKEQQKSFKEMLFVIILSIVIILTALMFQF 872 + A+ +++ + +K+ + I +G +++ S + ++ +S V++ L + Sbjct: 834 TSSGDAMALMENL--ASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALY 891 Query: 873 GDFKISISTLLALILTLIGVFMALLLTAKPLDITAFMGMLIVLSIAINNNILIFDFYK-M 931 + I +S +L + L ++GV +A L + D+ +G+L + ++ N ILI +F K + Sbjct: 892 ESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDL 951 Query: 932 SEKNHLSETEKIVAATSTRFRPIMMTMLSNSFAMLPIALTIGSGTQILQDMAIAIIGGLL 991 EK E + A R RPI+MT L+ +LP+A++ G+G+ + I ++GG++ Sbjct: 952 MEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMV 1011 Query: 992 FAIFVNLWIIPMFFHFIKKK 1011 A + ++ +P+FF I++ Sbjct: 1012 SATLLAIFFVPVFFVVIRRC 1031
>SECA#SecA protein signature. Length = 901 Score = 31.8 bits (72), Expect = 0.006 Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 229 IIFVKSEDKLKALEKLLKEHQGTSTIVFVKTK--RDAAEIEKELQKRSINARAIHGDLSQ 286 ++++ +K++A+ + +KE V V T + + EL K I ++ Sbjct: 426 LVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHA 485 Query: 287 RQRENVMKAFKEGKVKTLVATDVAARGIDIK 317 + V +A V +AT++A RG DI Sbjct: 486 NEAAIVAQAGYPAAVT--IATNMAGRGTDIV 514
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 29.7 bits (66), Expect = 0.006 Identities = 12/33 (36%), Positives = 19/33 (57%), Gaps = 5/33 (15%) Query: 34 IIFKDITPLLHK-----PWAFQKIIDYIGNRYI 61 II ++ PL ++ P FQ I++ I N+YI Sbjct: 203 IIMTEVAPLFNECAMPTPQQFQLILENIANKYI 235
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 248 bits (634), Expect = 2e-82 Identities = 119/341 (34%), Positives = 202/341 (59%), Gaps = 7/341 (2%) Query: 3 EEEKLQRTERITGAQKAAILILTLPEDIAVNVIKNLKEHELNKLAKTILTLGTIKRDMVK 62 +E+++ +TG QKAAIL++++ +I+ V K L + E+ L I L TI ++ Sbjct: 5 KEKEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKD 64 Query: 63 LVLKEARDEL-AEIAPLKTAPNELRRLLEKALPPEKLQKLLEETMMTESGKVIFNELQKL 121 VL E ++ + A+ K + R LLEK+L +K ++ + F +++ Sbjct: 65 NVLLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSR-PFEFVRRA 123 Query: 122 DPKFIAKLIEKEHPQIIAIILSQLKPTKAADVIQYLPKRLGITNVQEEVIKRLAMLEKVS 181 DP I I++EHPQ IA+ILS L P KA+ ++ LP T VQ V +R+A++++ S Sbjct: 124 DPANILNFIQQEHPQTIALILSYLDPQKASFILSSLP-----TEVQTNVARRIALMDRTS 178 Query: 182 MKTLRIVTDALEEELASLGAGKEETLSGIDIAAEIVNNLPKEIAQDLLDEIRKENPSLAD 241 + +R V LE++LASL + + G+D EI+N ++ + +++ + +E+P LA+ Sbjct: 179 PEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAE 238 Query: 242 SIEERMFKFEDIIKLDNRAIIEILKAVDKNDLLLALKGAPEDILNKFLSNMSKRAAQMFL 301 I+++MF FEDI+ LD+R+I +L+ +D +L ALK + K NMSKRAA M Sbjct: 239 EIKKKMFVFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLK 298 Query: 302 EDMEALGPVKKSDVEKARKKVIAIIKKLAEEGKIELGGSEE 342 EDME LGP ++ DVE++++K++++I+KL E+G+I + E Sbjct: 299 EDMEFLGPTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 177 bits (449), Expect = 8e-55 Identities = 85/340 (25%), Positives = 153/340 (45%), Gaps = 13/340 (3%) Query: 4 EFLSQEEIDALLGGDSN-------SSSEEQKLEVAPFDFSLVEHIKKGGVPGLELLLERW 56 E LSQ+EID LL S+ + ++ +DF + K + L L+ E + Sbjct: 3 EVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETF 62 Query: 57 IKIYSEEIRRLVPQINMVTKESVYITRFNNFMSKIPLPASYSIVSMKPLKDNFLLVLDSR 116 ++ + + + + V SV + F+ IP P++ ++++M PLK N +L +D Sbjct: 63 ARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPS 122 Query: 117 LVFVVISVMFGGPAQPFKIEGREFTKLETRIIDDIVKISLSTFQHTWKDVYPVEFELKSI 176 + F +I +FGG Q K++ R+ T +E +++ ++ L+ + +W V + L I Sbjct: 123 ITFSIIDRLFGGTGQAAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 177 ELNPALARIVSGNDRVIVVECTMDVDGYEAPFFFCFPQGMFLPIKELIFS----EAVFAE 232 E NP A+IV ++ V++V V E FC P PI + S +V Sbjct: 182 ETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRRS 241 Query: 233 KDPVWEKHLTKKLLKTELKLTLELTRKNFFLRELLSWKEGDEILL-DISKDEFVKLYVED 291 + L KL ++ + E+ +R++L + GD I L D + L + + Sbjct: 242 STTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGN 301 Query: 292 KPKFWAKLGKIKDKYAALVVDMINGENNGGKREKSGTEPE 331 + KF + G + K AA +++ I + E S E E Sbjct: 302 RKKFLCQPGVVGKKIAAQILERIESTSQEDFEELSADEEE 341
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 89.2 bits (221), Expect = 4e-26 Identities = 41/117 (35%), Positives = 72/117 (61%) Query: 4 WENALKEQESLEGEEEQVEEKEVSDYERKEEEEEKLELLKDIPLEVSIEIGSTSLPLEEI 63 W +AL EQ++ + + + ++L+ DIP+++++E+G T + ++E+ Sbjct: 19 WADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKEL 78 Query: 64 LKLHTNSIVELDRYIHEPVDIKINGKLVAKGKLYTIRENYGIKITQIITPEERMKLL 120 L+L S+V LD EP+DI ING L+A+G++ + + YG++IT IITP ERM+ L Sbjct: 79 LRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 30.3 bits (68), Expect = 0.006 Identities = 10/32 (31%), Positives = 18/32 (56%) Query: 8 LYVLAAGGERAVEQLDTAANNIANINTPGFKK 39 + +G A L+TA+NNI++ N G+ + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTR 35
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 48.0 bits (114), Expect = 2e-08 Identities = 12/43 (27%), Positives = 22/43 (51%) Query: 223 LEASNVNIVEEMVNLIVAQRAYEVNSKGITTADEMLRVVGTLK 265 S VN+ EE NL Q+ Y N++ + TA+ + + ++ Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 46.5 bits (110), Expect = 5e-08 Identities = 17/79 (21%), Positives = 35/79 (44%), Gaps = 14/79 (17%) Query: 5 LWTSATGMEAQQTNLDVISHNIANVNTVGFKKSRANFEDLIYQDIRDPGVMSSEENRVPS 64 + + +G+ A Q L+ S+NI++ N G+ + +M+ + + + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTT--------------IMAQANSTLGA 49 Query: 65 GIQIGLGVKVSDVSKIFTQ 83 G +G GV VS V + + Sbjct: 50 GGWVGNGVYVSGVQREYDA 68
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 148 bits (375), Expect = 1e-46 Identities = 58/202 (28%), Positives = 101/202 (50%), Gaps = 15/202 (7%) Query: 38 KPLPPPPVEEAKPTSPGSLFS-------GYDNLFADTKARRVGDIVTVKIYEVLTGYGST 90 +P+P P P + GS+F GY LF D + R +GD +T+ + E ++ S+ Sbjct: 38 QPVPGP-----TPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSS 92 Query: 91 QSQSGKKSTFDINVNNPTLFGKKIPNGTKDPLLNFSTKPSIDFSGQGTTKRDAKLIATIS 150 + + + + + + + + + F+G+G T++ Sbjct: 93 SANASRDGKTNFGFDTV---PRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLT 149 Query: 151 ARVVKVYPNGNLYIVGEKIVKINDDTQILKISGIVKPTDIAPDNSVPSSKIANMYVEYNG 210 V +V NGNL++VGEK + IN T+ ++ SG+V P I+ N+VPS+++A+ +EY G Sbjct: 150 VTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVG 209 Query: 211 KGYIADNQKPGWLARFLIKIWP 232 GYI + Q GWL RF + + P Sbjct: 210 NGYINEAQNMGWLQRFFLNLSP 231
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 347 bits (892), Expect = e-121 Identities = 137/346 (39%), Positives = 200/346 (57%), Gaps = 7/346 (2%) Query: 24 VKIGTEVNIVGVRPNYLTGYGIVVGLDGTGDGTTSI-FTLQSIANMLKKMGIYVDPKAVK 82 +I ++ R N L GYG+VVGL GTGD S FT QS+ ML+ +GI Sbjct: 29 SRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQSN 88 Query: 83 TKNAAAVIVTAKLPPFAKPGMTFDVEVASLGDAKSLANGILIRTPLLGPDGKIYAFAQGP 142 KN AAV+VTA LPPFA PG DV V+SLGDA SL G LI T L G DG+IYA AQG Sbjct: 89 AKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQGA 148 Query: 143 VSTGGGFTESNKGGKIKKNFSTTGMIPNGGIVERELPFELSNEKNLILTLKHPDFSRANN 202 + GF+ + + +T+ +PNG I+ERELP + + NL+L L++PDFS A Sbjct: 149 LIV-NGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 203 IAFAINNY----FGKNLAKAEDSSTVIVKYLPNYNKVKFISEILNLKINTESEPTIVIYE 258 +A +N + +G +A+ DS + V+ + + ++EI NL + T++ +VI E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 259 RTGTVIMSGDIKIEPPVYVSHGNIYVSVTKTPVISQPPPLSNGTTVQTENVTTTVKEEHG 318 RTGT+++ D++I V VS+G + V VT++P + QP P S G T +E Sbjct: 268 RTGTIVIGADVRIS-RVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGS 326 Query: 319 RIFSITSPSLRDLVKALNDLGVSPGDLIAIIQAMKAAGKLHAKIII 364 ++ + P LR LV LN +G+ +IAI+Q +K+AG L A++++ Sbjct: 327 KVAIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQAELVL 372
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.015 Identities = 19/116 (16%), Positives = 42/116 (36%), Gaps = 7/116 (6%) Query: 179 WTVIFVTTWFIFFFVIYSAFRENVFFFLFVSAAVAAAFCAFLYLLNRYGISKIFPSPETM 238 W V + T F F + S ++ F + +S A+ + R G K+ + Sbjct: 20 WGV-YTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIIL 78 Query: 239 EQIMYQSVAVGFVFLTIGIILGAVWAKYAWGGYWSWDPKETWSLITWLVYAAYLHA 294 +++ V +G V+ + ++W A+ T L +++ + Sbjct: 79 -RVLPACVVIGMVWF---VANTSIWRLLAFINT--KPVAFTLPLALSIIFNVVVVT 128
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.3 bits (66), Expect = 0.016 Identities = 22/153 (14%), Positives = 54/153 (35%), Gaps = 19/153 (12%) Query: 124 LAGFFYRNLAVILAIFLLWIFMFVFYLAKYLIAALLPQIPILSILSSLLVPILLFAILIS 183 L+ +++ + + ++ I ++ Y++ +L + L + ++ A + Sbjct: 45 LSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVV 104 Query: 184 MYYFLL---PIKIRFNFI---------FKISTFVFLLLTVFEKIFIWFIFNV-------S 224 Y FL+ IK I F I + V L ++ + + + + + + Sbjct: 105 QYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVT 164 Query: 225 KVSILYSSFAAIIIFLLWIYYSAIVILIGVGIV 257 + + I L I +VI +V Sbjct: 165 LLQLPTCGIECITPLLGQILRQLMVICTVGFVV 197
>SECA#SecA protein signature. Length = 901 Score = 34.5 bits (79), Expect = 0.002 Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 5/80 (6%) Query: 416 RLVQGDV-----GSGKTVVAAAAAFFAAKSGYQTAVMAPTEILANQHFKKFREFLKPFSI 470 L + + G GKT+ A A+ A +G V+ + LA + + R + + Sbjct: 93 VLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGL 152 Query: 471 KVGLLTGSMTKKEKETMYRA 490 VG+ M K Y A Sbjct: 153 TVGINLPGMPAPAKREAYAA 172
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 48.8 bits (116), Expect = 7e-09 Identities = 20/116 (17%), Positives = 48/116 (41%), Gaps = 1/116 (0%) Query: 289 INRLVKLDPYNLRLLSWVAASLFEMKEYKKVIPLIERITKLNPDNPNVYFMLGLAYEMSG 348 I L ++ L L +A + ++ +Y+ + + + L+ + + LG + G Sbjct: 25 IAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMG 84 Query: 349 NYEKALEAYEKSLDLYPENPTVLEKTAFLLYKMNRLSDAKAYFERLWQLT-NKPGY 403 Y+ A+ +Y + + P A L + L++A++ +L +K + Sbjct: 85 QYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEF 140 Score = 44.9 bits (106), Expect = 1e-07 Identities = 35/143 (24%), Positives = 53/143 (37%), Gaps = 7/143 (4%) Query: 456 GYLKKLLQIEP-SPDVYNYLAYFYANRGINLDEAEKLAEKALKAEPENPAFLDTLGWVLY 514 G + L +I + + LA+ G ++A K+ + + + F LG Sbjct: 23 GTIAMLNEISSDTLEQLYSLAFNQYQSG-KYEDAHKVFQALCVLDHYDSRFFLGLGACRQ 81 Query: 515 KKGDYKNACKYLEKALKLKQDDPVISEHYGECLYKTGRLKEAKEYLLKASSKIEKDPSIQ 574 G Y A + +P H ECL + G L EA+ L A I Sbjct: 82 AMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKT--- 138 Query: 575 KEEKGILQRIRKILREIK-IKEM 596 E K + R+ +L IK KEM Sbjct: 139 -EFKELSTRVSSMLEAIKLKKEM 160 Score = 39.1 bits (91), Expect = 1e-05 Identities = 20/114 (17%), Positives = 36/114 (31%), Gaps = 3/114 (2%) Query: 255 LEKVLDKNPDNIYALKEIFIIYLKQNKTNEALNVINRLVKLDPYNLRLLSWVAASLFEMK 314 L ++ + +Y+L + K +A V L LD Y+ R + A M Sbjct: 28 LNEISSDTLEQLYSLA---FNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMG 84 Query: 315 EYKKVIPLIERITKLNPDNPNVYFMLGLAYEMSGNYEKALEAYEKSLDLYPENP 368 +Y I ++ P F G +A + +L + Sbjct: 85 QYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKT 138
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.006 Identities = 18/86 (20%), Positives = 28/86 (32%), Gaps = 30/86 (34%) Query: 49 VLGIIGPNGAGKSTLLKILTGVIIPDEGKIHIDGRITGLLELGTGFNFEMTGIENIYLNG 108 + + G G GKSTL+ L G+ D ++GTG + Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL------DFFSD----THFDIGTGKDSYE---------- 637 Query: 109 MLLGMTKEELDRKKDSIIEFSELGDF 134 + G+ E SE+ F Sbjct: 638 QIAGIV----------AYELSEMTAF 653
>PF01540#Adhesin lipoprotein Length = 475 Score = 31.6 bits (71), Expect = 0.007 Identities = 23/99 (23%), Positives = 47/99 (47%) Query: 313 YVSALKLEALELKKAAFEDLKQIKKEKSMQLDDSWHKLKQAEEKIKNLKRKLLNDYKIYK 372 ++ + E E+KKA ++L +IK E +L + K+K+ +++ L K+ + Sbjct: 208 WLEKIVSEWEEVKKAWSKELAEIKAEDDKKLAEENQKIKEGAKELLKLSEKIQSFADTIA 267 Query: 373 VIKKALEKGLKTEIDLKNQEVEIVRDKILLNEEVHTFST 411 + LE+ + + K Q + + + EV TF+T Sbjct: 268 LTITKLERKFQIDEKFKKQLISTIELLNKKSVEVKTFAT 306 Score = 29.7 bits (66), Expect = 0.028 Identities = 24/95 (25%), Positives = 43/95 (45%) Query: 317 LKLEALELKKAAFEDLKQIKKEKSMQLDDSWHKLKQAEEKIKNLKRKLLNDYKIYKVIKK 376 + E E+KKA ++L +IK E +L + K+K E++K + + K Sbjct: 333 IVSEWEEVKKAWSKELAEIKAEDDKKLAEENQKIKNGVEELKKINNEAFELSKTVNKTIA 392 Query: 377 ALEKGLKTEIDLKNQEVEIVRDKILLNEEVHTFST 411 LEK K ++ K Q D + + ++ F+T Sbjct: 393 ELEKKFKIDVSFKEQLKNFADDLLDKSRQIDEFTT 427
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 248 bits (635), Expect = 2e-79 Identities = 89/428 (20%), Positives = 178/428 (41%), Gaps = 10/428 (2%) Query: 33 KKYITFGSLVVFLIFGLLIGWAALAKIDTVVVAPGKVVVKSYKKPVQHKDWGTVTRIFVK 92 + + + + + L +++ V A GK+ K ++ + V I VK Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 93 EGDFVKKGDPLLELEKLEQDTNYKVLESNYYNLLAERDRLLS-----EKKGLNHIAFSSE 147 EG+ V+KGD LL+L L + + +S+ E+ R E L + E Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 148 FLQFKNKKLKEQIIRTQRELFFKRKRKLQSELAVLSERENQAKEQLKGLKSVLKIKENLL 207 + + E+ + L ++ Q++ ++ + + + + + ENL Sbjct: 174 PY---FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 208 NSYIKEIKEQEELVKEKLVSKIRLLDLMKEKERLEAEIKDIKSKIPQVLSQIEELNHQKT 267 + + L+ ++ ++K +L+ + E++ KS++ Q+ S+I + Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 268 LQIENYQNEVASKLDEVLSKLSELKPKVIYAKEKVKKTIITANTSGQVLGLKIHAKGEVV 327 L + ++NE+ KL + + L ++ +E+ + ++I A S +V LK+H +G VV Sbjct: 291 LVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVV 350 Query: 328 KPGDTLMYIVPKKDEIFILAKVLPQDRDRVSKGQLVDLHFPAFLSIAANIVEGKVTYVAT 387 +TLM IVP+ D + + A V +D ++ GQ + AF + GKV + Sbjct: 351 TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Query: 388 DTLFDQATRHDYYETHIVLTDKGKEQLKKYGFNLVPGMPAVAYIKVEKVTPLEYVLQPVL 447 D + DQ + + + K L GM A IK + + Y+L P+ Sbjct: 411 DAIEDQRLGLVFNVIISIEENCLSTGNK--NIPLSSGMAVTAEIKTGMRSVISYLLSPLE 468 Query: 448 MLVKTAFK 455 V + + Sbjct: 469 ESVTESLR 476
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 190 bits (485), Expect = 2e-60 Identities = 73/331 (22%), Positives = 145/331 (43%), Gaps = 26/331 (7%) Query: 1 MKLVVTGGAGFIGSEFVRQAVEKGLETVVVDKLTYAGDL----ERLKEVENK-ISFYKAD 55 MK +VTG AGFIG ++ +E G + V +D L D+ RL+ + F+K D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 56 ITNREFIEHIFKAEKPDVVVHWAAESHVDRSILDATPFIETNVKGTQILLDVAKETGVNL 115 + +RE + +F + + V V S+ + + ++N+ G +L+ + + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 116 FVNIATDEVYGELGEDGQFYEDTPLN-PNSPYSVSKASADMLGRAYYRTYGLPVITVRPS 174 + ++ VYG L F D ++ P S Y+ +K + +++ Y YGLP +R Sbjct: 121 LLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 175 NNYGYWQYPEKLIPVVILKALNNEPIPIYGTGENRREWLFVSDCAEAVFEIIE------- 227 YG W P+ + L + I +Y G+ +R++ ++ D AEA+ + + Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 228 -----------KGKPGEIYNVGSGEERRNIDVVKSILQILNKPEDLITFVKDRPGHDFRY 276 P +YN+G+ +D ++++ L + +PG Sbjct: 240 QWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK-KNMLPLQPGDVLET 298 Query: 277 SLNTEKIEKELSWKAKVKFEEGIEKTVKWYL 307 S +T+ + + + + + ++G++ V WY Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.1 bits (112), Expect = 3e-08 Identities = 46/202 (22%), Positives = 76/202 (37%), Gaps = 29/202 (14%) Query: 1 MRYLIFGAKGQLGREFVKWL--SGGLV-----------ESLKGKTVEWIGVGR---EECD 44 M+YL+ GA G +G K L +G V SLK +E + + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 45 ISDLNQVLELFESTKPNVVVNCAAYNLVDKAEEDYVSAVKVNSVGVRNLAFACNRYR-AF 103 ++D + +LF S V V + E+ + N G N+ C + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 104 LVHYSTDYVFDGKKENALYIEDDKPN-PLNEYGKSKLIGEEFIKEEIDNFLI----LRVS 158 L++ S+ V+ G + DD + P++ Y +K E + + LR Sbjct: 121 LLYASSSSVY-GLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 159 WVYGE-GRQN-----FIYKLLK 174 VYG GR + F +L+ Sbjct: 180 TVYGPWGRPDMALFKFTKAMLE 201
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 188 bits (478), Expect = 2e-59 Identities = 90/346 (26%), Positives = 150/346 (43%), Gaps = 43/346 (12%) Query: 1 MKILVTGGAGYIGSHVVKALGEKGYKVLVVDNLSKGH----KEAVLYG------KLVVAD 50 MK LVTG AG+IG HV K L E G++V+ +DNL+ + K+A L + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 51 LEDKNTLDVIFKEFRPDAVMHFAAFIEVAQSLREPLKYYKNNTVNTINLLEVMLKNGVNK 110 L D+ + +F + V + V SL P Y +N +N+LE N + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 111 FIFSSTAAVYGNPEKVPIPEIEPI-KPINPYGQSKAFVEKVLQDFDKSYGLKYVSLRYFN 169 +++S+++VYG K+P + + P++ Y +K E + + YGL LR+F Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 170 AAGADPEGRIGESHDPETHLIPLILKTAKGEKESIKIFGTDYPTPDGTCIRDYIHVDDLA 229 G P GR P+ L +G +SI ++ G RD+ ++DD+A Sbjct: 181 VYG--PWGR------PDMALFKFTKAMLEG--KSIDVYN------YGKMKRDFTYIDDIA 224 Query: 230 EAHILALEYLLNGGSS---------------EVFNCGYGHGFSVREVIDTARKVTGIDFK 274 EA I + + + + V+N G + + I GI+ K Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 275 VEETERRPGDPAILVADSSKLRKVLDWKPKFDDLEYIIRTAWNWER 320 +PGD AD+ L +V+ + P+ ++ ++ NW R Sbjct: 285 KNMLPLQPGDVLETSADTKALYEVIGFTPET-TVKDGVKNFVNWYR 329
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 43.3 bits (102), Expect = 2e-06 Identities = 36/169 (21%), Positives = 55/169 (32%), Gaps = 42/169 (24%) Query: 193 DIVGQ----YQAKRALEIAAAGHHNLFMIGPPGSGKTMLARRLPTIMPPMSEEEIVETTK 248 +VG+ + R L L + G G+GK ++AR Sbjct: 138 PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR------------------- 178 Query: 249 IYSVAGLFSEIPVVKRPFRAPHSGA-----SEVALIG-------GGASLKPGEVSLSHNG 296 L PF A + A E L G G + G + G Sbjct: 179 -----ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 297 VLFLDEMAEFKRSALEALRQPLEDGFVTISRASGTVTFPANFSLVAASN 345 LFLDE+ + A L + L+ G + G ++ +VAA+N Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQG--EYTTVGGRTPIRSDVRIVAATN 280
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 391 bits (1006), Expect = e-139 Identities = 124/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%) Query: 1 MKTVFLTGAAGFIGYKTAEILIQKGYNVIGVDNLNNYYDVRLKEYRLKNLEKNKNFKFYQ 60 MK +TGAAGFIG+ ++ L++ G+ V+G+DNLN+YYDV LK+ RL+ L + F+F++ Sbjct: 1 MK-YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ-PGFQFHK 58 Query: 61 VDIENFGALKVIFEDNKIDGVINLAARAGVRYSLIDPFVYVRTNTTGTLNLLELMKDKKV 120 +D+ + + +F + V R VRYSL +P Y +N TG LN+LE + K+ Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 121 KKFVLASTSSLY-AGQPMPFKEDLPVNTPISPYAASKKGAEAVAYSYHYLYGIDVTVLRY 179 + + AS+SS+Y + MPF D V+ P+S YAA+KK E +A++Y +LYG+ T LR+ Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 180 FTVYGPIGRPDMSIFRFIKWIDEGKPIEIFGDGTQSRDFTYIDDIAKGTVKALETET--- 236 FTVYGP GRPDM++F+F K + EGK I+++ G RDFTYIDDIA+ ++ + Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHAD 238 Query: 237 ---------------GYEIINLGGNKPYELNYVIELIEEYIGKKAEKIYKPFHKADLKAT 281 Y + N+G + P EL I+ +E+ +G +A+K P D+ T Sbjct: 239 TQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLET 298 Query: 282 WADIEKAKRILDWEPQIPLEEGLKKTVDW 310 AD + ++ + P+ +++G+K V+W Sbjct: 299 SADTKALYEVIGFTPETTVKDGVKNFVNW 327