User Tools


Documentation

Data Input and Output

Complete List of Command Options

Guide to Command Usage

Common options

  • Genotype simulation options
  • Phenotype simulation options
  • Analysis options
  • Association tests options
  • Read more >>

Model specific options

Genetic Sequences

  • Population genetics model based simulation
    • spower simulate command for forward time simulation of DNA sequences
  • Data based simulation
  • Direct sampling from real world data-set
  • Read more >>

Disease Associations

Effects of variants

  • Fixed effect vs. variable effects
  • Protective, deleterious and neutral variants
  • Read more >>

Phenotype simulations

  • Linear mean-shift model
  • Extreme quantitative trait model
  • Logit model of odds ratios
  • Population attributable risk model
  • Linear model with qualitative outcome
  • Phenotype simulation for sequences drawn from haplotype pools
  • Read more >>

Power of Association Tests

Rare Variants Association Methods (RVAM)

Evaluating Novel Statistical Tests