Searching... please wait. You've got 8 hits!
| Gene 1 | Gene 2 | Interaction Type | Sentence | Value | Judge me |
| Smad | Brk | bind1 | Brk bound to a Dpp response element of the Ultrabithorax ( Ubx ) midgut enhancer at a sequence that overlaps a binding site for the Smad protein , Mothers Against Dpp ( Mad ) . | 18 | good bad |
| Smad | BRCA2 | associate2 | Finally , analysis of a small cohort of hereditary breast cancers failed to reveal any association between BRCA1 or BRCA2 genotype and alterations in Smad signaling . | 17 | good bad |
| Smad | neu | associate1 | Loss of Smad signaling was not associated with any particular histological subtype , histological or nuclear grade , estrogen- or progesterone receptor expression , or HER2 neu expression . | 17 | good bad |
| Smad | Smad4 | bind1 | While there are two potential Smad binding elements ( SBE ' s ) in the TGFbeta ( 1 ) promoter , supershift assays suggest that at least one of these does not bind Smad4 , and the other is unable to bi | 17 | good bad |
| Smad | tinman | bind2 | We show that the binding and synergistic activities of Smad and Tinman proteins are critical for mesodermal tinman induction , whereas repressor binding sites prevent induction in the dorsal ectoderm | 17 | good bad |
| Smad | Brk | complex1 | In addition to the ligand-activated heteromeric receptor complex and the signal-transducing intracellular Smad proteins , Dpp signaling requires two nuclear proteins , Schnurri ( Shn ) and Brinker ( B | 16 | good bad |
| Smad | tinman | interact3 | A similar regulatory interaction has been defined in Drosophila embryos where Dpp signaling mediated by the Smad homologues Mad and Medea directly regulates early cardiac expression of tinman . | 15 | good bad |
| Smad | Smad4 | complex3 | Smad proteins activated by TGF-beta form complexes with Smad4 . | 8 | good bad |
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Text2Knowledge ... Yong Huang
2002
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