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Tag Homepage Description Notes
ABySS Assembly http://www.bcgsc.ca/platform/bioinfo/software/abyss "ABySS is a de novo sequence assembler that is designed for very short reads. The single-processor version is useful for assembling genomes up to 40-50 Mbases in size. The parallel version is implemented using MPI and is capable of assembling larger genomes." None
ALLPATHS Assembly (de novo) http://www.ncbi.nlm.nih.gov/pubmed/18340039 De novo assembly of whole-genome shotgun microreads. None
AMOS Assembly http://amos.sourceforge.net/ The AMOS consortium is committed to the development of open-source whole genome assembly software. The project acronym (AMOS) represents our primary goal -- to produce A Modular, Open-Source whole genome assembler. None
Alta-Cyclic Base-calling http://hannonlab.cshl.edu/Alta-Cyclic/main.html Alta-Cyclic is a novel Illumina Genome-Analyzer (Solexa) base caller. Alta Cyclic Features: Longer Reads, More Accurate Reads (compared to Solexa's default base caller), Reduces systematic bias towrsd a certain nucleotide in later cycles. On a GAII platform, Alta Cyclic was able to provide a large amount of useful reads after 78 cycles. None
BOWTIE Alignment http://bowtie-bio.sourceforge.net/ Bowtie is an ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of 25 million reads per hour on a typical workstation with 2 gigabytes of memory. Bowtie indexes the genome with a Burrows-Wheeler index to keep its memory footprint small: 1.3 GB for the human genome. It supports alignment policies equivalent to Maq and SOAP but is much faster: about 35x faster than Maq and over 350x faster than SOAP when aligning to the human genome. None
BS-Seq Methylation http://epigenomics.mcdb.ucla.edu/BS-Seq/download.html The source code and data for the "Shotgun Bisulphite Sequencing of the Arabidopsis Genome Reveals DNA Methylation Patterning" Nature paper by Cokus et al. (Steve Jacobsen's lab at UCLA). POSIX. None
Batman Methylation http://www.nature.com/nbt/journal/v26/n7/abs/nbt1414.html Bayesian tool for methylation analysis (Batman)—for analyzing methylated DNA immunoprecipitation (MeDIP) profiles None
CABOG Assembly http://wgs-assembler.sf.net/ Celera Assembler is scientific software for DNA research. CA is a 'whole genome shotgun sequence assembler' -- it reconstructs long sequences of genomic DNA given the fragmentary data produced by whole-genome shotgun sequencing. Celera Assembler was modified for combinations of ABI 3730 and 454 FLX reads. The revised pipeline called CABOG (Celera Assembler with the Best Overlap Graph) is robust to homopolymer run length uncertainty, high read coverage, and heterogeneous read lengths (pubmed). None
CARPET Analysis http://bio.ifom-ieo-campus.it/galaxy Collection of Automated Routine Programs for Easy Tiling) is a set of Perl, Python and R scripts, integrated on the Galaxy2 web-based platform, for the analysis of ChIP-chip and expression tiling data, both for standard and custom chip designs. None
CATCH ChIPseq / ChIP-chip http://www.cmbi.ru.nl/%7Efnielsen/CATCH CATCH is an tool for exploring patterns in ChIP profiling data. The CATCH algorithm performs a hierachical clustering of the profile patterns with an exhaustive alignment at each step. The algorithm has a user-friendly graphical interface that makes it easy for you to browse your results. None
CHiPSeq Enrichment/peak calling http://woldlab.caltech.edu/chipseq/ From Science Johnson, 2007 None
CLCbio Genomics Workbench Integrated solutions http://www.clcbio.com/index.php?id=1240 de novo and reference assembly of Sanger, 454, Solexa, Helicos, and SOLiD data. Commercial next-gen-seq software that extends the CLCbio Main Workbench software. Includes SNP detection, browser and other features. Runs on Windows, Mac OS X and Linux. None
CNVseq CNV http://tiger.dbs.nus.edu.sg/CNV-seq/ CNV-seq, a method to detect copy number variation using high-throughput sequencing. pubmed None
ChIPmeta ChIPseq http://www.umich.edu/%7Ehwchoi/HHMMsoftware.zip In this work, hierarchical hidden Markov model (HHMM) is proposed for combining data from ChIP-seq and ChIP-chip. In HHMM, inference results from individual HMMs in ChIP-seq and ChIP-chip experiments are summarized by a higher level HMM. Simulation studies show the advantage of HHMM when data from both technologies co-exist. Analysis of two well-studied transcription factors, NRSF and CTCF, also suggests that HHMM yields improved TFBS identification in comparison to analyses using individual data sources or a simple merger of the two. pubmed None
ChromaSig Chromatine Profiling http://bioinformatics-renlab.ucsd.edu/rentrac/wiki/ChromaSig An unsupervised learning method, which finds, in an unbiased fashion, commonly occurring chromatin signatures in both tiling microarray and sequencing data. None
CisGenome Integrated solutions http://www.biostat.jhsph.edu/%7Ehji/cisgenome/ An integrated tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis None
CleaveLand microRNA http://www.bio.psu.edu/people/faculty/Axtell/AxtellLab/Software.html A pipeline for using degradome data to find cleaved small RNA targets. None
CloudBurst Mapping http://apps.sourceforge.net/mediawiki/cloudburst-bio/index.php?title=CloudBurst CloudBurst is a new parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes, for use in a variety of biological analyses including SNP discovery, genotyping, and personal genomics. It is modeled after the short read mapping program RMAP, and reports either all alignments or the unambiguous best alignment for each read with any number of mismatches or differences. This level of sensitivity could be prohibitively time consuming, but CloudBurst uses the open-source Hadoop implementation of MapReduce to parallelize execution using multiple compute nodes. pubmed None
Consensus Assembly http://www.seqan.de/projects/consensus.html SeqCons is an open source consensus computation program for Linux and Windows. The algorithm can be used for de novo and reference-guided sequence assembly. None
DNAzip Misc http://www.ics.uci.edu/%7Exhx/project/DNAzip A series of techniques that in combination reduces a single genome to a size small enough to be sent as an email attachment. pubmed None
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