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root/gclib/tophat_cpp/gdna.cpp
Revision: 154
Committed: Tue Jan 24 02:29:21 2012 UTC (12 years, 7 months ago) by gpertea
File size: 1267 byte(s)
Log Message:
massive update with Daehwan's work

Line File contents
1 #include "gdna.h"
2 #include <string.h>
3
4 #define IUPAC_DEFS "AaCcTtGgUuMmRrWwSsYyKkVvHhDdBbNnXx-*"
5 #define IUPAC_COMP "TtGgAaCcAaKkYyWwSsRrMmBbDdHhVvNnXx-*"
6
7 unsigned char ntCompTable[256];
8
9 static bool gdna_ntCompTableReady=ntCompTableInit();
10
11 char ntComplement(char c) {
12 return ntCompTable[(int)c];
13 }
14
15 //in place reverse complement of nucleotide (sub)sequence
16 char* reverseComplement(char* seq, int slen) {
17 if (slen==0) slen=strlen(seq);
18 //reverseChars(seq,len);
19 int l=0;
20 int r=slen-1;
21 register char c;
22 while (l<r) {
23 c=seq[l];seq[l]=seq[r];
24 seq[r]=c; //this was: Gswap(str[l],str[r]);
25 l++;r--;
26 }
27 for (int i=0;i<slen;i++) seq[i]=ntComplement(seq[i]);
28 return seq;
29 }
30
31 bool ntCompTableInit() {
32 //if (gdna_ntCompTableReady) return true;
33 char n[]=IUPAC_DEFS;
34 char c[]=IUPAC_COMP;
35 int l=strlen(IUPAC_DEFS);
36 ntCompTable[0]=0;
37 for (int ch=1;ch<256;ch++) {
38 ntCompTable[ch]=0;
39 for (int i=0;i<l;i++)
40 if (ch==n[i]) {
41 ntCompTable[ch]=c[i];
42 break;
43 }
44 if (ntCompTable[ch]==0)
45 ntCompTable[ch]='N';
46 }
47 //gdna_ntCompTableReady=true;
48 return true;
49 }