Basic Information
Gene ID 100459532
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Pongo abelii [9601]

Cross Reference
UniProt H2PP52 UniGene NULL
PDB NULL OMIM NULL
KEGG pon:100459532 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000020420 Gene3D G3DSA:1.10.10.60 IPR009057 230 304 2.50e-25 Homeodomain-like
ENSPPYP00000020420 Pfam PF00046 IPR001356 247 303 1.20e-21 Homeobox domain
ENSPPYP00000020420 Pfam PF10525 IPR019549 304 335 7.60e-17 Homeobox engrailed, C-terminal
ENSPPYP00000020420 PRINTS PR00024 IPR020479 268 279 2.30e-06 Homeodomain, metazoa
ENSPPYP00000020420 PRINTS PR00024 IPR020479 283 293 2.30e-06 Homeodomain, metazoa
ENSPPYP00000020420 PRINTS PR00024 IPR020479 293 302 2.30e-06 Homeodomain, metazoa
ENSPPYP00000020420 PRINTS PR00026 IPR000747 245 262 6.60e-17 Homeodomain engrailed
ENSPPYP00000020420 PRINTS PR00026 IPR000747 308 325 6.60e-17 Homeodomain engrailed
ENSPPYP00000020420 ProSitePatterns PS00027 IPR017970 279 302 - Homeobox, conserved site
ENSPPYP00000020420 ProSitePatterns PS00033 IPR019737 315 322 - Homeobox engrailed-type, conserved site
ENSPPYP00000020420 ProSiteProfiles PS50071 IPR001356 244 304 0.00e-00 Homeobox domain
ENSPPYP00000020420 SMART SM00389 IPR001356 246 308 7.10e-28 Homeobox domain
ENSPPYP00000020420 SUPERFAMILY SSF46689 IPR009057 237 303 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000020420 PF00046 7.7e-22 Homeobox Homeobox domain
ENSPPYP00000020420 PF10525 3.9e-17 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000020420 GO:0005634 cellular_component nucleus
ENSPPYP00000020420 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100161671 10224 Saccoglossus kowalevskii 100303466
7425 Nasonia vitripennis 100123905 43179 Ictidomys tridecemlineatus 101960578
9606 Homo sapiens 2020 9646 Ailuropoda melanoleuca ENSAMEG00000001224
99883 Tetraodon nigroviridis ENSTNIG00000012777 9823 Sus scrofa 100512078
61853 Nomascus leucogenys 100581025 30195 Bombus terrestris 100649797
8128 Oreochromis niloticus 100706716 132113 Bombus impatiens 100743858
7463 Apis florea 100870890 34638 Metaseiulus occidentalis 100908620
30611 Otolemur garnettii 100946410 9597 Pan paniscus 100996220
9555 Papio anubis 101019723 39432 Saimiri boliviensis 101033660
31033 Takifugu rubripes 101068755 8083 Xiphophorus maculatus 102234767
7897 Latimeria chalumnae 102360063 7227 Drosophila melanogaster 36240
7070 Tribolium castaneum 661645 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 28377 Anolis carolinensis ENSACAG00000011018
9913 Bos taurus ENSBTAG00000018917 9615 Canis familiaris ENSCAFG00000005082
9483 Callithrix jacchus ENSCJAG00000017450 10141 Cavia porcellus ENSCPOG00000024572
51511 Ciona savignyi ENSCSAVG00000008099 7955 Danio rerio ENSDARG00000038868
9796 Equus caballus ENSECAG00000021744 9365 Erinaceus europaeus ENSEEUG00000004213
9371 Echinops telfairi ENSETEG00000004995 9685 Felis catus ENSFCAG00000023560
69293 Gasterosteus aculeatus ENSGACG00000003888 9595 Gorilla gorilla ENSGGOG00000022981
8049 Gadus morhua ENSGMOG00000004983 9785 Loxodonta africana ENSLAFG00000032115
9103 Meleagris gallopavo ENSMGAG00000012331 59463 Myotis lucifugus ENSMLUG00000004165
13616 Monodelphis domestica ENSMODG00000004978 9669 Mustela putorius furo ENSMPUG00000009596
9258 Ornithorhynchus anatinus ENSOANG00000006149 9986 Oryctolagus cuniculus ENSOCUG00000002453
8090 Oryzias latipes ENSORLG00000010437 7757 Petromyzon marinus ENSPMAG00000010362
13735 Pelodiscus sinensis ENSPSIG00000014871 132908 Pteropus vampyrus ENSPVAG00000003106
59729 Taeniopygia guttata ENSTGUG00000000695 9739 Tursiops truncatus ENSTTRG00000013702

Paralogs
ENSPPYG00000012793