Basic Information
Gene ID 100585171
Gene Name STAT2
Full Name Signal transducer and activator of transcription
Organism Nomascus leucogenys [61853]

Cross Reference
UniProt G1S6V0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSNLEP00000021239 Gene3D G3DSA:1.10.238.10 IPR011992 459 580 2.20e-44 EF-hand domain pair
ENSNLEP00000021239 Gene3D G3DSA:1.10.532.10 IPR013799 1 124 1.20e-33 STAT transcription factor, protein interaction
ENSNLEP00000021239 Gene3D G3DSA:1.20.1050.20 IPR013800 140 316 2.30e-53 STAT transcription factor, all-alpha
ENSNLEP00000021239 Gene3D G3DSA:2.60.40.630 IPR012345 317 458 9.10e-50 STAT transcription factor, DNA-binding, subdomain
ENSNLEP00000021239 Gene3D G3DSA:3.30.505.10 IPR000980 581 703 1.10e-44 SH2 domain
ENSNLEP00000021239 PANTHER PTHR11801 IPR001217 2 769 0.00e-00 Transcription factor STAT
ENSNLEP00000021239 Pfam PF00017 IPR000980 577 647 2.50e-10 SH2 domain
ENSNLEP00000021239 Pfam PF01017 IPR013800 140 313 2.00e-50 STAT transcription factor, all-alpha
ENSNLEP00000021239 Pfam PF02864 IPR013801 316 566 2.40e-100 STAT transcription factor, DNA-binding
ENSNLEP00000021239 Pfam PF02865 IPR013799 2 124 1.10e-36 STAT transcription factor, protein interaction
ENSNLEP00000021239 Pfam PF12188 IPR022756 783 838 8.30e-33 Signal transducer and activation of transcription 2, C-terminal
ENSNLEP00000021239 ProSiteProfiles PS50001 IPR000980 572 667 0.00e-00 SH2 domain
ENSNLEP00000021239 SMART SM00252 IPR000980 570 654 1.60e-08 SH2 domain
ENSNLEP00000021239 SMART SM00964 IPR013799 2 125 4.10e-63 STAT transcription factor, protein interaction
ENSNLEP00000021239 SUPERFAMILY SSF47655 IPR015988 139 316 0.00e-00 STAT transcription factor, coiled coil
ENSNLEP00000021239 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSNLEP00000021239 SUPERFAMILY SSF49417 IPR008967 317 567 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSNLEP00000021239 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSNLEP00000021239 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSNLEP00000021239 PF02865 1.1e-36 STAT_int STAT protein, protein interaction domain
ENSNLEP00000021239 PF12188 8.3e-33 STAT2_C Signal transducer and activator of transcription 2 C terminal
ENSNLEP00000021239 PF00017 9.9e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSNLEP00000021239 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSNLEP00000021239 GO:0007259 biological_process JAK-STAT cascade
ENSNLEP00000021239 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSNLEP00000021239 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSNLEP00000021239 GO:0005634 cellular_component nucleus
ENSNLEP00000021239 GO:0005737 cellular_component cytoplasm
ENSNLEP00000021239 GO:0003677 molecular_function DNA binding
ENSNLEP00000021239 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSNLEP00000021239 GO:0004871 molecular_function signal transducer activity
ENSNLEP00000021239 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100972085 9555 Papio anubis 101011342
39432 Saimiri boliviensis 101029836 9595 Gorilla gorilla 101146695
10090 Mus musculus 20847 9606 Homo sapiens 6773
9544 Macaca mulatta 712694 28377 Anolis carolinensis ENSACAG00000023449
9646 Ailuropoda melanoleuca ENSAMEG00000003886 9913 Bos taurus ENSBTAG00000004380
9615 Canis familiaris ENSCAFG00000000121 9358 Choloepus hoffmanni ENSCHOG00000012984
9483 Callithrix jacchus ENSCJAG00000011101 10141 Cavia porcellus ENSCPOG00000014930
9361 Dasypus novemcinctus ENSDNOG00000011002 10020 Dipodomys ordii ENSDORG00000012958
9796 Equus caballus ENSECAG00000022326 9365 Erinaceus europaeus ENSEEUG00000010238
9685 Felis catus ENSFCAG00000012023 9785 Loxodonta africana ENSLAFG00000014890
9315 Macropus eugenii ENSMEUG00000010173 30608 Microcebus murinus ENSMICG00000000089
59463 Myotis lucifugus ENSMLUG00000006785 9669 Mustela putorius furo ENSMPUG00000001431
9258 Ornithorhynchus anatinus ENSOANG00000012739 30611 Otolemur garnettii ENSOGAG00000001538
9978 Ochotona princeps ENSOPRG00000001512 9813 Procavia capensis ENSPCAG00000007855
132908 Pteropus vampyrus ENSPVAG00000007596 9305 Sarcophilus harrisii ENSSHAG00000000508
9823 Sus scrofa ENSSSCG00000000396 43179 Ictidomys tridecemlineatus ENSSTOG00000015985
9478 Tarsius syrichta ENSTSYG00000007831 9739 Tursiops truncatus ENSTTRG00000007159