Basic Information | |||
Gene ID | 10062 ; ![]() ![]() | ||
Gene Name | NR1H3; LXRA | ||
Full Name | Oxysterols receptor LXR-alpha | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q13133 | UniGene | Hs.438863 |
PDB | 3IPU | OMIM | 602423 |
KEGG | hsa:10062 | UCSC | uc001nen.4 |
Protein Interactions | |
DIP | NULL |
IntAct | Q13133 |
MINT | MINT-3027136 |
STRING | 9606.ENSP00000342470 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
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REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001238864 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 158 | 199 | 4.20e-87 | Nuclear hormone receptor, ligand-binding |
NP_001238864 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 239 | 452 | 4.20e-87 | Nuclear hormone receptor, ligand-binding |
NP_001238864 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 104 | 157 | 6.70e-25 | Zinc finger, NHR/GATA-type |
NP_001238864 | Pfam | PF00104 | IPR000536 | 250 | 433 | 7.30e-35 | Nuclear hormone receptor, ligand-binding, core |
NP_001238864 | Pfam | PF00105 | IPR001628 | 103 | 170 | 5.20e-27 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | PRINTS | PR00047 | IPR001628 | 104 | 120 | 5.30e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | PRINTS | PR00047 | IPR001628 | 120 | 135 | 5.30e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | PRINTS | PR00047 | IPR001628 | 153 | 161 | 5.30e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | PRINTS | PR00047 | IPR001628 | 161 | 169 | 5.30e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | PRINTS | PR00398 | IPR001723 | 165 | 175 | 3.10e-24 | Steroid hormone receptor |
NP_001238864 | PRINTS | PR00398 | IPR001723 | 266 | 287 | 3.10e-24 | Steroid hormone receptor |
NP_001238864 | PRINTS | PR00398 | IPR001723 | 287 | 303 | 3.10e-24 | Steroid hormone receptor |
NP_001238864 | PRINTS | PR00398 | IPR001723 | 355 | 370 | 3.10e-24 | Steroid hormone receptor |
NP_001238864 | PRINTS | PR00398 | IPR001723 | 412 | 429 | 3.10e-24 | Steroid hormone receptor |
NP_001238864 | PRINTS | PR02034 | IPR023257 | 139 | 153 | 1.40e-40 | Liver X receptor |
NP_001238864 | PRINTS | PR02034 | IPR023257 | 320 | 335 | 1.40e-40 | Liver X receptor |
NP_001238864 | PRINTS | PR02034 | IPR023257 | 347 | 360 | 1.40e-40 | Liver X receptor |
NP_001238864 | PRINTS | PR02034 | IPR023257 | 422 | 439 | 1.40e-40 | Liver X receptor |
NP_001238864 | PRINTS | PR02034 | IPR023257 | 91 | 101 | 1.40e-40 | Liver X receptor |
NP_001238864 | ProSitePatterns | PS00031 | IPR001628 | 104 | 130 | - | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | ProSiteProfiles | PS51030 | IPR001628 | 101 | 176 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | SMART | SM00399 | IPR001628 | 101 | 172 | 4.80e-38 | Zinc finger, nuclear hormone receptor-type |
NP_001238864 | SMART | SM00430 | IPR000536 | 265 | 424 | 8.50e-45 | Nuclear hormone receptor, ligand-binding, core |
NP_001238864 | SUPERFAMILY | SSF48508 | IPR008946 | 212 | 451 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001238864 | PF00104 | 4.7e-35 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
NP_001238864 | PF00105 | 2.9e-27 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001238864 | GO:0005634 | cellular_component | nucleus |
NP_001238864 | GO:0003677 | molecular_function | DNA binding |
NP_001238864 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_001238864 | GO:0008270 | molecular_function | zinc ion binding |
NP_001238864 | GO:0043565 | molecular_function | sequence-specific DNA binding |