Basic Information
Gene ID 100949888
Gene Name STAT6
Full Name Signal transducer and activator of transcription
Organism Otolemur garnettii [30611]

Cross Reference
UniProt H0WR40 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOGAP00000004470 Gene3D G3DSA:1.10.238.10 IPR011992 415 540 4.20e-41 EF-hand domain pair
ENSOGAP00000004470 Gene3D G3DSA:1.10.532.10 IPR013799 1 113 2.70e-22 STAT transcription factor, protein interaction
ENSOGAP00000004470 Gene3D G3DSA:1.20.1050.20 IPR013800 114 272 6.90e-26 STAT transcription factor, all-alpha
ENSOGAP00000004470 Gene3D G3DSA:2.60.40.630 IPR012345 274 414 2.00e-43 STAT transcription factor, DNA-binding, subdomain
ENSOGAP00000004470 Gene3D G3DSA:3.30.505.10 IPR000980 541 649 6.90e-37 SH2 domain
ENSOGAP00000004470 PANTHER PTHR11801 IPR001217 2 717 0.00e-00 Transcription factor STAT
ENSOGAP00000004470 Pfam PF00017 IPR000980 537 615 3.20e-10 SH2 domain
ENSOGAP00000004470 Pfam PF01017 IPR013800 176 270 7.20e-22 STAT transcription factor, all-alpha
ENSOGAP00000004470 Pfam PF02864 IPR013801 272 526 6.00e-93 STAT transcription factor, DNA-binding
ENSOGAP00000004470 Pfam PF02865 IPR013799 2 115 1.60e-21 STAT transcription factor, protein interaction
ENSOGAP00000004470 Pfam PF14596 IPR028187 654 846 4.60e-105 STAT6, C-terminal
ENSOGAP00000004470 ProSiteProfiles PS50001 IPR000980 516 631 0.00e-00 SH2 domain
ENSOGAP00000004470 SMART SM00252 IPR000980 539 621 1.00e-07 SH2 domain
ENSOGAP00000004470 SMART SM00964 IPR013799 2 116 1.00e-36 STAT transcription factor, protein interaction
ENSOGAP00000004470 SUPERFAMILY SSF47655 IPR015988 112 272 0.00e-00 STAT transcription factor, coiled coil
ENSOGAP00000004470 SUPERFAMILY SSF48092 IPR013799 1 115 0.00e-00 STAT transcription factor, protein interaction
ENSOGAP00000004470 SUPERFAMILY SSF49417 IPR008967 264 527 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOGAP00000004470 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSOGAP00000004470 PF14596 0 STAT6_C STAT6 C-terminal
ENSOGAP00000004470 PF01017 2.7e-22 STAT_alpha STAT protein, all-alpha domain
ENSOGAP00000004470 PF02865 3e-22 STAT_int STAT protein, protein interaction domain
ENSOGAP00000004470 PF00017 1.3e-10 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOGAP00000004470 GO:0001553 biological_process luteinization
ENSOGAP00000004470 GO:0001779 biological_process natural killer cell differentiation
ENSOGAP00000004470 GO:0006351 biological_process transcription, DNA-templated
ENSOGAP00000004470 GO:0007259 biological_process JAK-STAT cascade
ENSOGAP00000004470 GO:0007565 biological_process female pregnancy
ENSOGAP00000004470 GO:0007595 biological_process lactation
ENSOGAP00000004470 GO:0019218 biological_process regulation of steroid metabolic process
ENSOGAP00000004470 GO:0019915 biological_process lipid storage
ENSOGAP00000004470 GO:0030155 biological_process regulation of cell adhesion
ENSOGAP00000004470 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSOGAP00000004470 GO:0038161 biological_process prolactin signaling pathway
ENSOGAP00000004470 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSOGAP00000004470 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSOGAP00000004470 GO:0043029 biological_process T cell homeostasis
ENSOGAP00000004470 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSOGAP00000004470 GO:0045579 biological_process positive regulation of B cell differentiation
ENSOGAP00000004470 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSOGAP00000004470 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSOGAP00000004470 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSOGAP00000004470 GO:0046543 biological_process development of secondary female sexual characteristics
ENSOGAP00000004470 GO:0050729 biological_process positive regulation of inflammatory response
ENSOGAP00000004470 GO:0005634 cellular_component nucleus
ENSOGAP00000004470 GO:0005737 cellular_component cytoplasm
ENSOGAP00000004470 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOGAP00000004470 GO:0004871 molecular_function signal transducer activity
ENSOGAP00000004470 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100050053 9823 Sus scrofa 100627682
10029 Cricetulus griseus 100753838 9597 Pan paniscus 100989067
9595 Gorilla gorilla 101130575 9669 Mustela putorius furo 101676980
43179 Ictidomys tridecemlineatus 101967693 13616 Monodelphis domestica ENSMODG00000019411
132908 Pteropus vampyrus ENSPVAG00000003949 8364 Xenopus tropicalis ENSXETG00000004431
9555 Papio anubis 101023204 39432 Saimiri boliviensis 101029869
9685 Felis catus 101089873 9544 Macaca mulatta 714159
28377 Anolis carolinensis ENSACAG00000009680 9483 Callithrix jacchus ENSCJAG00000010327
10020 Dipodomys ordii ENSDORG00000012548 9365 Erinaceus europaeus ENSEEUG00000005856
9371 Echinops telfairi ENSETEG00000014957 9785 Loxodonta africana ENSLAFG00000005970
9315 Macropus eugenii ENSMEUG00000016670 30608 Microcebus murinus ENSMICG00000009087
59463 Myotis lucifugus ENSMLUG00000006689 61853 Nomascus leucogenys ENSNLEG00000017396
9978 Ochotona princeps ENSOPRG00000013409 9813 Procavia capensis ENSPCAG00000009432
9601 Pongo abelii ENSPPYG00000004680 9598 Pan troglodytes ENSPTRG00000005121
42254 Sorex araneus ENSSARG00000001630 37347 Tupaia belangeri ENSTBEG00000013664
59729 Taeniopygia guttata ENSTGUG00000015716 9478 Tarsius syrichta ENSTSYG00000000267
9739 Tursiops truncatus ENSTTRG00000013064