Basic Information
Gene ID 1649 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name DDIT3; CHOP, CHOP10, GADD153
Full Name DNA damage-inducible transcript 3 protein
Organism Homo sapiens [9606]

Cross Reference
UniProt P35638 UniGene Hs.505777
PDB NULL OMIM 613488
KEGG hsa:1649 UCSC uc001soi.3

Protein Interactions
DIP NULL
IntAct P35638
MINT MINT-1434413
STRING 9606.ENSP00000340671

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_001181985 PANTHER PTHR16833 IPR016670 25 192 0.00e-00 DNA damage-inducible transcript 3
NP_001181985 Pfam PF07716 IPR004827 125 174 1.10e-04 Basic-leucine zipper domain
NP_001181985 PIRSF PIRSF016571 IPR016670 24 192 2.10e-130 DNA damage-inducible transcript 3
NP_001181985 ProSiteProfiles PS50217 IPR004827 122 185 0.00e-00 Basic-leucine zipper domain
NP_001181985 SMART SM00338 IPR004827 119 184 2.90e-07 Basic-leucine zipper domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_001181985 PF07716 6.5e-05 bZIP_2 Basic region leucine zipper

Gene Ontology Annotation
Protein Entry Name Space Description
NP_001181985 GO:0001955 biological_process blood vessel maturation
NP_001181985 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_001181985 GO:0006986 biological_process response to unfolded protein
NP_001181985 GO:0007050 biological_process cell cycle arrest
NP_001181985 GO:0016055 biological_process Wnt signaling pathway
NP_001181985 GO:0032757 biological_process positive regulation of interleukin-8 production
NP_001181985 GO:0034976 biological_process response to endoplasmic reticulum stress
NP_001181985 GO:0042594 biological_process response to starvation
NP_001181985 GO:0043161 biological_process proteasome-mediated ubiquitin-dependent protein catabolic process
NP_001181985 GO:0043525 biological_process positive regulation of neuron apoptotic process
NP_001181985 GO:0045662 biological_process negative regulation of myoblast differentiation
NP_001181985 GO:0045892 biological_process negative regulation of transcription, DNA-templated
NP_001181985 GO:0045893 biological_process positive regulation of transcription, DNA-templated
NP_001181985 GO:0051209 biological_process release of sequestered calcium ion into cytosol
NP_001181985 GO:0070059 biological_process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
NP_001181985 GO:0005634 cellular_component nucleus
NP_001181985 GO:0003677 molecular_function DNA binding
NP_001181985 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_001181985 GO:0043565 molecular_function sequence-specific DNA binding