Basic Information
Gene ID 17258 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Mef2a
Full Name Myocyte-specific enhancer factor 2A
Organism Mus musculus [10090]

Cross Reference
UniProt Q60929 UniGene Mm.491250
PDB NULL OMIM NULL
KEGG mmu:17258 UCSC uc009hii.2

Protein Interactions
DIP NULL
IntAct Q60929
MINT MINT-3155471
STRING 10090.ENSMUSP00000117496

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000117496 Pfam PF00319 IPR002100 10 59 8.10e-22 Transcription factor, MADS-box
ENSMUSP00000117496 Pfam PF12347 IPR022102 95 152 1.30e-05 Holliday junction regulator protein family C-terminal
ENSMUSP00000117496 PRINTS PR00404 IPR002100 23 38 1.40e-25 Transcription factor, MADS-box
ENSMUSP00000117496 PRINTS PR00404 IPR002100 3 23 1.40e-25 Transcription factor, MADS-box
ENSMUSP00000117496 PRINTS PR00404 IPR002100 38 59 1.40e-25 Transcription factor, MADS-box
ENSMUSP00000117496 ProSitePatterns PS00350 IPR002100 3 57 - Transcription factor, MADS-box
ENSMUSP00000117496 ProSiteProfiles PS50066 IPR002100 1 61 0.00e-00 Transcription factor, MADS-box
ENSMUSP00000117496 SMART SM00432 IPR002100 1 60 1.60e-39 Transcription factor, MADS-box
ENSMUSP00000117496 SUPERFAMILY SSF55455 IPR002100 2 89 0.00e-00 Transcription factor, MADS-box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000117496 PF00319 4.8e-22 SRF-TF SRF-type transcription factor (DNA-binding and dimerisation domain)
ENSMUSP00000117496 PF12347 3.8e-06 HJURP_C Holliday junction regulator protein family C-terminal repeat

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000117496 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSMUSP00000117496 GO:0000165 biological_process MAPK cascade
ENSMUSP00000117496 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000117496 GO:0006915 biological_process apoptotic process
ENSMUSP00000117496 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMUSP00000117496 GO:0071277 biological_process cellular response to calcium ion
ENSMUSP00000117496 GO:0005634 cellular_component nucleus
ENSMUSP00000117496 GO:0000977 molecular_function RNA polymerase II regulatory region sequence-specific DNA binding
ENSMUSP00000117496 GO:0000981 molecular_function sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSMUSP00000117496 GO:0003677 molecular_function DNA binding
ENSMUSP00000117496 GO:0003682 molecular_function chromatin binding
ENSMUSP00000117496 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9258 Ornithorhynchus anatinus 100076657 10224 Saccoglossus kowalevskii 100313657
30195 Bombus terrestris 100649884 132113 Bombus impatiens 100745731
7463 Apis florea 100871942 143995 Megachile rotundata 100877544
9597 Pan paniscus 100989820 9555 Papio anubis 101002825
39432 Saimiri boliviensis 101041298 31033 Takifugu rubripes 101063649
9685 Felis catus 101098464 7897 Latimeria chalumnae 102348604
13735 Pelodiscus sinensis 102454317 9796 Equus caballus 100050068
6087 Hydra magnipapillata 100204453 34638 Metaseiulus occidentalis 100902919
7227 Drosophila melanogaster 36032 9606 Homo sapiens 4205
7070 Tribolium castaneum 660448 9646 Ailuropoda melanoleuca ENSAMEG00000003398
51511 Ciona savignyi ENSCSAVG00000003571 10020 Dipodomys ordii ENSDORG00000015216
9315 Macropus eugenii ENSMEUG00000013873 9103 Meleagris gallopavo ENSMGAG00000009283
9669 Mustela putorius furo ENSMPUG00000010826 9986 Oryctolagus cuniculus ENSOCUG00000010966
59729 Taeniopygia guttata ENSTGUG00000008733 9739 Tursiops truncatus ENSTTRG00000003944
8083 Xiphophorus maculatus ENSXMAG00000003697 6239 Caenorhabditis elegans 172732
7460 Apis mellifera 413946 7668 Strongylocentrotus purpuratus 591326
28377 Anolis carolinensis ENSACAG00000000488 9615 Canis familiaris ENSCAFG00000010775
9358 Choloepus hoffmanni ENSCHOG00000010767 7719 Ciona intestinalis ENSCING00000000628
10141 Cavia porcellus ENSCPOG00000008716 7955 Danio rerio ENSDARG00000057527
9361 Dasypus novemcinctus ENSDNOG00000018848 9371 Echinops telfairi ENSETEG00000018987
69293 Gasterosteus aculeatus ENSGACG00000013182 9031 Gallus gallus ENSGALG00000007100
9595 Gorilla gorilla ENSGGOG00000013064 8049 Gadus morhua ENSGMOG00000015431
9785 Loxodonta africana ENSLAFG00000004656 59463 Myotis lucifugus ENSMLUG00000016420
9544 Macaca mulatta ENSMMUG00000018122 13616 Monodelphis domestica ENSMODG00000020223
30611 Otolemur garnettii ENSOGAG00000008728 8128 Oreochromis niloticus ENSONIG00000015126
9978 Ochotona princeps ENSOPRG00000014581 8090 Oryzias latipes ENSORLG00000008489
9813 Procavia capensis ENSPCAG00000013783 9601 Pongo abelii ENSPPYG00000006816
9598 Pan troglodytes ENSPTRG00000007496 132908 Pteropus vampyrus ENSPVAG00000014423
10116 Rattus norvegicus ENSRNOG00000033134 42254 Sorex araneus ENSSARG00000009233
9305 Sarcophilus harrisii ENSSHAG00000016994 9823 Sus scrofa ENSSSCG00000004815
43179 Ictidomys tridecemlineatus ENSSTOG00000028856 37347 Tupaia belangeri ENSTBEG00000006420
99883 Tetraodon nigroviridis ENSTNIG00000019231 9478 Tarsius syrichta ENSTSYG00000001620
30538 Vicugna pacos ENSVPAG00000011436 8364 Xenopus tropicalis ENSXETG00000018788

Paralogs
17259