Basic Information | |||
Gene ID | 2019 ; ![]() ![]() | ||
Gene Name | EN1 | ||
Full Name | Homeobox protein engrailed-1 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q05925 | UniGene | Hs.271977 |
PDB | NULL | OMIM | 131290 |
KEGG | hsa:2019 | UCSC | uc002tlm.3 |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | 9606.ENSP00000295206 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001417 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 287 | 361 | 1.70e-24 | Homeodomain-like |
NP_001417 | Pfam | PF00046 | IPR001356 | 304 | 360 | 2.40e-21 | Homeobox domain |
NP_001417 | Pfam | PF10525 | IPR019549 | 361 | 392 | 7.40e-19 | Homeobox engrailed, C-terminal |
NP_001417 | PRINTS | PR00024 | IPR020479 | 325 | 336 | 1.10e-05 | Homeodomain, metazoa |
NP_001417 | PRINTS | PR00024 | IPR020479 | 340 | 350 | 1.10e-05 | Homeodomain, metazoa |
NP_001417 | PRINTS | PR00024 | IPR020479 | 350 | 359 | 1.10e-05 | Homeodomain, metazoa |
NP_001417 | PRINTS | PR00026 | IPR000747 | 302 | 319 | 5.00e-18 | Homeodomain engrailed |
NP_001417 | PRINTS | PR00026 | IPR000747 | 365 | 382 | 5.00e-18 | Homeodomain engrailed |
NP_001417 | ProSitePatterns | PS00027 | IPR017970 | 336 | 359 | - | Homeobox, conserved site |
NP_001417 | ProSitePatterns | PS00033 | IPR019737 | 372 | 379 | - | Homeobox engrailed-type, conserved site |
NP_001417 | ProSiteProfiles | PS50071 | IPR001356 | 301 | 361 | 0.00e-00 | Homeobox domain |
NP_001417 | SMART | SM00389 | IPR001356 | 303 | 365 | 4.60e-27 | Homeobox domain |
NP_001417 | SUPERFAMILY | SSF46689 | IPR009057 | 301 | 361 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001417 | PF00046 | 1.6e-21 | Homeobox | Homeobox domain |
NP_001417 | PF10525 | 4e-19 | Engrail_1_C_sig | Engrailed homeobox C-terminal signature domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001417 | GO:0005634 | cellular_component | nucleus |
NP_001417 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001417 | GO:0043565 | molecular_function | sequence-specific DNA binding |