Basic Information | |||
Gene ID | 20852 ; ![]() ![]() | ||
Gene Name | Stat6 | ||
Full Name | Signal transducer and transcription activator 6 | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | P52633 | UniGene | Mm.121721 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:20852 | UCSC | uc007hka.1 |
Protein Interactions | |
DIP | DIP-49680N |
IntAct | P52633 |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_033310 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 416 | 541 | 1.80e-41 | EF-hand domain pair |
NP_033310 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 115 | 4.50e-23 | STAT transcription factor, protein interaction |
NP_033310 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 151 | 273 | 9.10e-25 | STAT transcription factor, all-alpha |
NP_033310 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 275 | 415 | 4.40e-45 | STAT transcription factor, DNA-binding, subdomain |
NP_033310 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 542 | 651 | 8.10e-37 | SH2 domain |
NP_033310 | PANTHER | PTHR11801 | IPR001217 | 2 | 720 | 0.00e-00 | Transcription factor STAT |
NP_033310 | Pfam | PF00017 | IPR000980 | 538 | 616 | 3.60e-10 | SH2 domain |
NP_033310 | Pfam | PF01017 | IPR013800 | 126 | 271 | 3.30e-24 | STAT transcription factor, all-alpha |
NP_033310 | Pfam | PF02864 | IPR013801 | 273 | 527 | 1.50e-93 | STAT transcription factor, DNA-binding |
NP_033310 | Pfam | PF02865 | IPR013799 | 2 | 114 | 2.30e-22 | STAT transcription factor, protein interaction |
NP_033310 | Pfam | PF14596 | IPR028187 | 655 | 837 | 1.10e-98 | STAT6, C-terminal |
NP_033310 | ProSiteProfiles | PS50001 | IPR000980 | 517 | 632 | 0.00e-00 | SH2 domain |
NP_033310 | SMART | SM00252 | IPR000980 | 540 | 622 | 6.90e-08 | SH2 domain |
NP_033310 | SMART | SM00964 | IPR013799 | 2 | 116 | 1.70e-35 | STAT transcription factor, protein interaction |
NP_033310 | SUPERFAMILY | SSF47655 | IPR015988 | 114 | 273 | 0.00e-00 | STAT transcription factor, coiled coil |
NP_033310 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 114 | 0.00e-00 | STAT transcription factor, protein interaction |
NP_033310 | SUPERFAMILY | SSF49417 | IPR008967 | 265 | 528 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_033310 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
NP_033310 | PF14596 | 0 | STAT6_C | STAT6 C-terminal |
NP_033310 | PF01017 | 2.7e-26 | STAT_alpha | STAT protein, all-alpha domain |
NP_033310 | PF02865 | 4.7e-23 | STAT_int | STAT protein, protein interaction domain |
NP_033310 | PF00017 | 1.4e-10 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_033310 | GO:0001553 | biological_process | luteinization |
NP_033310 | GO:0001779 | biological_process | natural killer cell differentiation |
NP_033310 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_033310 | GO:0007259 | biological_process | JAK-STAT cascade |
NP_033310 | GO:0007565 | biological_process | female pregnancy |
NP_033310 | GO:0007595 | biological_process | lactation |
NP_033310 | GO:0019218 | biological_process | regulation of steroid metabolic process |
NP_033310 | GO:0019915 | biological_process | lipid storage |
NP_033310 | GO:0030155 | biological_process | regulation of cell adhesion |
NP_033310 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
NP_033310 | GO:0038161 | biological_process | prolactin signaling pathway |
NP_033310 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
NP_033310 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
NP_033310 | GO:0043029 | biological_process | T cell homeostasis |
NP_033310 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
NP_033310 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
NP_033310 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
NP_033310 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
NP_033310 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
NP_033310 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
NP_033310 | GO:0050729 | biological_process | positive regulation of inflammatory response |
NP_033310 | GO:0005634 | cellular_component | nucleus |
NP_033310 | GO:0005737 | cellular_component | cytoplasm |
NP_033310 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_033310 | GO:0004871 | molecular_function | signal transducer activity |
NP_033310 | GO:0005509 | molecular_function | calcium ion binding |