Basic Information | |||
Gene ID | 2100 ; ![]() ![]() | ||
Gene Name | ESR2; ESTRB, NR3A2 | ||
Full Name | Estrogen receptor beta | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | Q92731 | UniGene | Hs.734416 |
PDB | 4J26 | OMIM | 601663 |
KEGG | hsa:2100 | UCSC | uc010aqc.1 |
Protein Interactions | |
DIP | DIP-5966N |
IntAct | Q92731 |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001428 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 203 | 498 | 4.30e-78 | Nuclear hormone receptor, ligand-binding |
NP_001428 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 149 | 202 | 6.00e-28 | Zinc finger, NHR/GATA-type |
NP_001428 | Pfam | PF00104 | IPR000536 | 283 | 475 | 5.10e-35 | Nuclear hormone receptor, ligand-binding, core |
NP_001428 | Pfam | PF00105 | IPR001628 | 148 | 216 | 3.60e-31 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | Pfam | PF12497 | IPR021064 | 12 | 123 | 1.20e-34 | Estrogen receptor beta, N-terminal |
NP_001428 | PIRSF | PIRSF002527 | IPR024178 | 23 | 530 | 3.00e-288 | Oestrogen receptor/oestrogen-related receptor |
NP_001428 | PIRSF | PIRSF500102 | IPR028355 | 1 | 530 | 0.00e-00 | Estrogen receptor beta/gamma |
NP_001428 | PRINTS | PR00047 | IPR001628 | 149 | 165 | 5.20e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | PRINTS | PR00047 | IPR001628 | 165 | 180 | 5.20e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | PRINTS | PR00047 | IPR001628 | 198 | 206 | 5.20e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | PRINTS | PR00047 | IPR001628 | 206 | 214 | 5.20e-17 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | PRINTS | PR00398 | IPR001723 | 210 | 220 | 1.60e-23 | Steroid hormone receptor |
NP_001428 | PRINTS | PR00398 | IPR001723 | 301 | 322 | 1.60e-23 | Steroid hormone receptor |
NP_001428 | PRINTS | PR00398 | IPR001723 | 322 | 338 | 1.60e-23 | Steroid hormone receptor |
NP_001428 | PRINTS | PR00398 | IPR001723 | 390 | 405 | 1.60e-23 | Steroid hormone receptor |
NP_001428 | PRINTS | PR00398 | IPR001723 | 457 | 474 | 1.60e-23 | Steroid hormone receptor |
NP_001428 | ProSitePatterns | PS00031 | IPR001628 | 149 | 175 | - | Zinc finger, nuclear hormone receptor-type |
NP_001428 | ProSiteProfiles | PS51030 | IPR001628 | 146 | 221 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | SMART | SM00399 | IPR001628 | 146 | 217 | 5.90e-37 | Zinc finger, nuclear hormone receptor-type |
NP_001428 | SMART | SM00430 | IPR000536 | 300 | 469 | 3.70e-36 | Nuclear hormone receptor, ligand-binding, core |
NP_001428 | SUPERFAMILY | SSF48508 | IPR008946 | 262 | 498 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001428 | PF00104 | 3.3e-35 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
NP_001428 | PF12497 | 6.8e-35 | ERbeta_N | Estrogen receptor beta |
NP_001428 | PF00105 | 1.7e-31 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001428 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_001428 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
NP_001428 | GO:0030520 | biological_process | intracellular estrogen receptor signaling pathway |
NP_001428 | GO:0005634 | cellular_component | nucleus |
NP_001428 | GO:0003677 | molecular_function | DNA binding |
NP_001428 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001428 | GO:0003707 | molecular_function | steroid hormone receptor activity |
NP_001428 | GO:0005496 | molecular_function | steroid binding |
NP_001428 | GO:0008270 | molecular_function | zinc ion binding |
NP_001428 | GO:0030284 | molecular_function | estrogen receptor activity |
NP_001428 | GO:0043565 | molecular_function | sequence-specific DNA binding |