Basic Information
Gene ID 2308 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXO1; FKHR, FOXO1A
Full Name Forkhead box protein O1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q12778 UniGene Hs.370666
PDB 3COA OMIM 268220
KEGG hsa:2308 UCSC uc001uxl.4

Protein Interactions
DIP DIP-35654N
IntAct Q12778
MINT NULL
STRING 9606.ENSP00000368880

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_002006 Gene3D G3DSA:1.10.10.10 IPR011991 152 241 3.10e-43 Winged helix-turn-helix DNA-binding domain
NP_002006 Pfam PF00250 IPR001766 163 245 3.50e-22 Transcription factor, fork head
NP_002006 PRINTS PR00053 IPR001766 160 173 7.40e-12 Transcription factor, fork head
NP_002006 PRINTS PR00053 IPR001766 181 198 7.40e-12 Transcription factor, fork head
NP_002006 PRINTS PR00053 IPR001766 209 226 7.40e-12 Transcription factor, fork head
NP_002006 ProSitePatterns PS00658 IPR018122 209 215 - Transcription factor, fork head, conserved site
NP_002006 ProSiteProfiles PS50039 IPR001766 160 254 0.00e-00 Transcription factor, fork head
NP_002006 SMART SM00339 IPR001766 158 248 1.40e-45 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_002006 PF00250 1.9e-22 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_002006 GO:0043066 biological_process negative regulation of apoptotic process
NP_002006 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_002006 GO:0005634 cellular_component nucleus
NP_002006 GO:0005737 cellular_component cytoplasm
NP_002006 GO:0043565 molecular_function sequence-specific DNA binding