Basic Information
Gene ID 3170 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXA2; HNF3B, TCF3B
Full Name Hepatocyte nuclear factor 3-beta
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9Y261 UniGene Hs.155651
PDB NULL OMIM 600288
KEGG hsa:3170 UCSC uc002wsn.3

Protein Interactions
DIP NULL
IntAct Q9Y261
MINT MINT-6610868
STRING 9606.ENSP00000315955

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_068556 Gene3D G3DSA:1.10.10.10 IPR011991 158 252 2.10e-41 Winged helix-turn-helix DNA-binding domain
NP_068556 Pfam PF00250 IPR001766 165 260 1.30e-46 Transcription factor, fork head
NP_068556 Pfam PF08430 IPR013638 23 164 1.90e-23 Fork-head N-terminal
NP_068556 Pfam PF09354 IPR018533 379 452 9.20e-23 Forkhead box protein, C-terminal
NP_068556 PRINTS PR00053 IPR001766 165 178 2.80e-24 Transcription factor, fork head
NP_068556 PRINTS PR00053 IPR001766 186 203 2.80e-24 Transcription factor, fork head
NP_068556 PRINTS PR00053 IPR001766 209 226 2.80e-24 Transcription factor, fork head
NP_068556 ProSitePatterns PS00657 IPR018122 165 178 - Transcription factor, fork head, conserved site
NP_068556 ProSitePatterns PS00658 IPR018122 209 215 - Transcription factor, fork head, conserved site
NP_068556 ProSiteProfiles PS50039 IPR001766 165 259 0.00e-00 Transcription factor, fork head
NP_068556 SMART SM00339 IPR001766 163 253 1.60e-64 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_068556 PF00250 0 Fork_head Fork head domain
NP_068556 PF08430 1.9e-23 Fork_head_N Forkhead N-terminal region
NP_068556 PF09354 9.2e-23 HNF_C HNF3 C-terminal domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_068556 GO:0006351 biological_process transcription, DNA-templated
NP_068556 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_068556 GO:0005634 cellular_component nucleus
NP_068556 GO:0003677 molecular_function DNA binding
NP_068556 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_068556 GO:0008134 molecular_function transcription factor binding
NP_068556 GO:0019904 molecular_function protein domain specific binding
NP_068556 GO:0043565 molecular_function sequence-specific DNA binding