Basic Information
Gene ID 3399 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ID3; 1R21, BHLHB25, HEIR1
Full Name DNA-binding protein inhibitor ID-3
Organism Homo sapiens [9606]

Cross Reference
UniProt Q02535 UniGene Hs.76884
PDB 2LFH OMIM 600277
KEGG hsa:3399 UCSC uc001bhh.4

Protein Interactions
DIP DIP-713N
IntAct Q02535
MINT NULL
STRING 9606.ENSP00000363689

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_002158 Gene3D G3DSA:4.10.280.10 IPR011598 42 85 1.10e-08 Myc-type, basic helix-loop-helix (bHLH) domain
NP_002158 PANTHER PTHR11723 IPR026052 2 119 0.00e-00 DNA-binding protein inhibitor
NP_002158 Pfam PF00010 IPR011598 42 81 7.70e-11 Myc-type, basic helix-loop-helix (bHLH) domain
NP_002158 ProSiteProfiles PS50888 IPR011598 28 80 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
NP_002158 SMART SM00353 IPR011598 32 86 3.60e-12 Myc-type, basic helix-loop-helix (bHLH) domain
NP_002158 SUPERFAMILY SSF47459 IPR011598 42 86 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_002158 PF00010 5.3e-11 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_002158 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
NP_002158 GO:0007275 biological_process multicellular organismal development
NP_002158 GO:0045892 biological_process negative regulation of transcription, DNA-templated
NP_002158 GO:0005634 cellular_component nucleus
NP_002158 GO:0005737 cellular_component cytoplasm
NP_002158 GO:0046983 molecular_function protein dimerization activity