Basic Information
Gene ID 3664 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name IRF6
Full Name Interferon regulatory factor 6
Organism Homo sapiens [9606]

Cross Reference
UniProt O14896 UniGene Hs.591415
PDB NULL OMIM 608864
KEGG hsa:3664 UCSC uc001hhq.2

Protein Interactions
DIP NULL
IntAct O14896
MINT NULL
STRING 9606.ENSP00000355988

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_006138 Gene3D G3DSA:1.10.10.10 IPR011991 5 114 4.30e-44 Winged helix-turn-helix DNA-binding domain
NP_006138 Gene3D G3DSA:2.60.200.10 IPR017855 213 453 1.30e-93 SMAD domain-like
NP_006138 Pfam PF00605 IPR001346 7 115 9.50e-48 Interferon regulatory factor DNA-binding domain
NP_006138 Pfam PF10401 IPR019471 223 407 5.60e-64 Interferon regulatory factor-3
NP_006138 PRINTS PR00267 IPR001346 35 48 1.20e-26 Interferon regulatory factor DNA-binding domain
NP_006138 PRINTS PR00267 IPR001346 53 70 1.20e-26 Interferon regulatory factor DNA-binding domain
NP_006138 PRINTS PR00267 IPR001346 76 98 1.20e-26 Interferon regulatory factor DNA-binding domain
NP_006138 PRINTS PR00267 IPR001346 9 28 1.20e-26 Interferon regulatory factor DNA-binding domain
NP_006138 ProSitePatterns PS00601 IPR019817 28 61 - Interferon regulatory factor, conserved site
NP_006138 ProSiteProfiles PS51507 IPR001346 7 115 0.00e-00 Interferon regulatory factor DNA-binding domain
NP_006138 SMART SM00348 IPR001346 3 116 6.80e-62 Interferon regulatory factor DNA-binding domain
NP_006138 SUPERFAMILY SSF49879 IPR008984 215 444 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_006138 PF00605 0 IRF Interferon regulatory factor transcription factor
NP_006138 PF10401 0 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
NP_006138 GO:0006351 biological_process transcription, DNA-templated
NP_006138 GO:0005634 cellular_component nucleus
NP_006138 GO:0005737 cellular_component cytoplasm
NP_006138 GO:0000975 molecular_function regulatory region DNA binding
NP_006138 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity