Basic Information
Gene ID 397276
Gene Name TP53; P53
Full Name Cellular tumor antigen p53
Organism Sus scrofa [9823]

Cross Reference
UniProt Q9TUB2 UniGene Ssc.15917
PDB NULL OMIM NULL
KEGG ssc:397276 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9823.ENSSSCP00000019016

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_998989 Gene3D G3DSA:2.60.40.720 IPR012346 87 287 3.50e-96 p53/RUNT-type transcription factor, DNA-binding domain
NP_998989 Gene3D G3DSA:4.10.170.10 IPR010991 312 351 3.20e-20 p53, tetramerisation domain
NP_998989 PANTHER PTHR11447 IPR002117 1 386 0.00e-00 p53 tumour suppressor family
NP_998989 Pfam PF00870 IPR011615 88 281 8.30e-110 p53, DNA-binding domain
NP_998989 Pfam PF07710 IPR010991 312 350 4.10e-19 p53, tetramerisation domain
NP_998989 Pfam PF08563 IPR013872 5 29 1.00e-12 p53 transactivation domain
NP_998989 PRINTS PR00386 IPR002117 108 134 1.10e-86 p53 tumour suppressor family
NP_998989 PRINTS PR00386 IPR002117 150 171 1.10e-86 p53 tumour suppressor family
NP_998989 PRINTS PR00386 IPR002117 206 227 1.10e-86 p53 tumour suppressor family
NP_998989 PRINTS PR00386 IPR002117 229 251 1.10e-86 p53 tumour suppressor family
NP_998989 PRINTS PR00386 IPR002117 257 279 1.10e-86 p53 tumour suppressor family
NP_998989 PRINTS PR00386 IPR002117 319 343 1.10e-86 p53 tumour suppressor family
NP_998989 ProSitePatterns PS00348 IPR002117 230 242 - p53 tumour suppressor family
NP_998989 SUPERFAMILY SSF47719 IPR010991 312 348 0.00e-00 p53, tetramerisation domain
NP_998989 SUPERFAMILY SSF49417 IPR008967 89 280 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_998989 PF00870 0 P53 P53 DNA-binding domain
NP_998989 PF07710 2.1e-19 P53_tetramer P53 tetramerisation motif
NP_998989 PF08563 4.3e-13 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
NP_998989 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
NP_998989 GO:0000733 biological_process DNA strand renaturation
NP_998989 GO:0006289 biological_process nucleotide-excision repair
NP_998989 GO:0006351 biological_process transcription, DNA-templated
NP_998989 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_998989 GO:0006915 biological_process apoptotic process
NP_998989 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
NP_998989 GO:0007049 biological_process cell cycle
NP_998989 GO:0007275 biological_process multicellular organismal development
NP_998989 GO:0007569 biological_process cell aging
NP_998989 GO:0010165 biological_process response to X-ray
NP_998989 GO:0010332 biological_process response to gamma radiation
NP_998989 GO:0012501 biological_process programmed cell death
NP_998989 GO:0030308 biological_process negative regulation of cell growth
NP_998989 GO:0031065 biological_process positive regulation of histone deacetylation
NP_998989 GO:0034644 biological_process cellular response to UV
NP_998989 GO:0042771 biological_process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
NP_998989 GO:0043525 biological_process positive regulation of neuron apoptotic process
NP_998989 GO:0051262 biological_process protein tetramerization
NP_998989 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
NP_998989 GO:0097252 biological_process oligodendrocyte apoptotic process
NP_998989 GO:0005634 cellular_component nucleus
NP_998989 GO:0005657 cellular_component replication fork
NP_998989 GO:0005730 cellular_component nucleolus
NP_998989 GO:0005737 cellular_component cytoplasm
NP_998989 GO:0005739 cellular_component mitochondrion
NP_998989 GO:0005759 cellular_component mitochondrial matrix
NP_998989 GO:0005783 cellular_component endoplasmic reticulum
NP_998989 GO:0005829 cellular_component cytosol
NP_998989 GO:0003677 molecular_function DNA binding
NP_998989 GO:0003682 molecular_function chromatin binding
NP_998989 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_998989 GO:0005507 molecular_function copper ion binding
NP_998989 GO:0005524 molecular_function ATP binding
NP_998989 GO:0044212 molecular_function transcription regulatory region DNA binding
NP_998989 GO:0046872 molecular_function metal ion binding