Basic Information
Gene ID 397671
Gene Name PPARG; NR1C3
Full Name Peroxisome proliferator-activated receptor gamma
Organism Sus scrofa [9823]

Cross Reference
UniProt O62807 UniGene Ssc.14475
PDB NULL OMIM NULL
KEGG ssc:397671 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSSCP00000012339 Gene3D G3DSA:1.10.565.10 IPR008946 191 221 1.10e-75 Nuclear hormone receptor, ligand-binding
ENSSSCP00000012339 Gene3D G3DSA:1.10.565.10 IPR008946 277 501 1.10e-75 Nuclear hormone receptor, ligand-binding
ENSSSCP00000012339 Gene3D G3DSA:3.30.50.10 IPR013088 138 190 2.20e-24 Zinc finger, NHR/GATA-type
ENSSSCP00000012339 Pfam PF00104 IPR000536 320 483 1.10e-30 Nuclear hormone receptor, ligand-binding, core
ENSSSCP00000012339 Pfam PF00105 IPR001628 137 203 2.70e-27 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 Pfam PF12577 IPR022590 30 107 3.90e-33 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSSSCP00000012339 PRINTS PR00047 IPR001628 138 154 6.00e-19 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 PRINTS PR00047 IPR001628 154 169 6.00e-19 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 PRINTS PR00047 IPR001628 186 194 6.00e-19 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 PRINTS PR00047 IPR001628 194 202 6.00e-19 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 PRINTS PR00398 IPR001723 198 208 7.30e-28 Steroid hormone receptor
ENSSSCP00000012339 PRINTS PR00398 IPR001723 315 336 7.30e-28 Steroid hormone receptor
ENSSSCP00000012339 PRINTS PR00398 IPR001723 336 352 7.30e-28 Steroid hormone receptor
ENSSSCP00000012339 PRINTS PR00398 IPR001723 404 419 7.30e-28 Steroid hormone receptor
ENSSSCP00000012339 PRINTS PR00398 IPR001723 461 478 7.30e-28 Steroid hormone receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 227 241 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 241 260 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 354 367 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 371 386 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 389 402 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 451 468 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01288 IPR003074 485 497 4.00e-64 Peroxisome proliferator-activated receptor
ENSSSCP00000012339 PRINTS PR01291 IPR003077 102 120 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 PRINTS PR01291 IPR003077 214 230 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 PRINTS PR01291 IPR003077 41 55 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 PRINTS PR01291 IPR003077 438 451 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 PRINTS PR01291 IPR003077 59 72 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 PRINTS PR01291 IPR003077 84 101 2.30e-54 Peroxisome proliferator-activated receptor, gamma
ENSSSCP00000012339 ProSitePatterns PS00031 IPR001628 138 164 - Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 ProSiteProfiles PS51030 IPR001628 135 209 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 SMART SM00399 IPR001628 135 205 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012339 SMART SM00430 IPR000536 314 473 6.30e-30 Nuclear hormone receptor, ligand-binding, core
ENSSSCP00000012339 SUPERFAMILY SSF48508 IPR008946 239 502 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSSCP00000012339 PF12577 1.5e-33 PPARgamma_N PPAR gamma N-terminal region
ENSSSCP00000012339 PF00104 5e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSSSCP00000012339 PF00105 1.7e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSSCP00000012339 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSSSCP00000012339 GO:0001890 biological_process placenta development
ENSSSCP00000012339 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSSCP00000012339 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSSSCP00000012339 GO:0008217 biological_process regulation of blood pressure
ENSSSCP00000012339 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSSSCP00000012339 GO:0010887 biological_process negative regulation of cholesterol storage
ENSSSCP00000012339 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSSSCP00000012339 GO:0015909 biological_process long-chain fatty acid transport
ENSSSCP00000012339 GO:0030224 biological_process monocyte differentiation
ENSSSCP00000012339 GO:0030855 biological_process epithelial cell differentiation
ENSSSCP00000012339 GO:0032526 biological_process response to retinoic acid
ENSSSCP00000012339 GO:0032869 biological_process cellular response to insulin stimulus
ENSSSCP00000012339 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSSSCP00000012339 GO:0042593 biological_process glucose homeostasis
ENSSSCP00000012339 GO:0042953 biological_process lipoprotein transport
ENSSSCP00000012339 GO:0045165 biological_process cell fate commitment
ENSSSCP00000012339 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSSSCP00000012339 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSSSCP00000012339 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSSSCP00000012339 GO:0048469 biological_process cell maturation
ENSSSCP00000012339 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSSSCP00000012339 GO:0050872 biological_process white fat cell differentiation
ENSSSCP00000012339 GO:0050873 biological_process brown fat cell differentiation
ENSSSCP00000012339 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSSSCP00000012339 GO:0055098 biological_process response to low-density lipoprotein particle
ENSSSCP00000012339 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSSSCP00000012339 GO:0071285 biological_process cellular response to lithium ion
ENSSSCP00000012339 GO:0005634 cellular_component nucleus
ENSSSCP00000012339 GO:0005829 cellular_component cytosol
ENSSSCP00000012339 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSSSCP00000012339 GO:0003677 molecular_function DNA binding
ENSSSCP00000012339 GO:0003682 molecular_function chromatin binding
ENSSSCP00000012339 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSSCP00000012339 GO:0003707 molecular_function steroid hormone receptor activity
ENSSSCP00000012339 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSSSCP00000012339 GO:0008144 molecular_function drug binding
ENSSSCP00000012339 GO:0008270 molecular_function zinc ion binding
ENSSSCP00000012339 GO:0019899 molecular_function enzyme binding
ENSSSCP00000012339 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSSSCP00000012339 GO:0033613 molecular_function activating transcription factor binding
ENSSSCP00000012339 GO:0043565 molecular_function sequence-specific DNA binding
ENSSSCP00000012339 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
34638 Metaseiulus occidentalis 100899165 9305 Sarcophilus harrisii 100934154
30611 Otolemur garnettii 100943160 9669 Mustela putorius furo 101688974
10116 Rattus norvegicus 25664 9031 Gallus gallus 373928
9796 Equus caballus 100051258 61853 Nomascus leucogenys 100581046
10029 Cricetulus griseus 100689245 8128 Oreochromis niloticus 100711231
132113 Bombus impatiens 100744917 143995 Megachile rotundata 100876784
9597 Pan paniscus 100974825 9555 Papio anubis 101012073
39432 Saimiri boliviensis 101028278 9685 Felis catus 101095161
9595 Gorilla gorilla 101134077 59463 Myotis lucifugus 102435787
10090 Mus musculus 19016 7227 Drosophila melanogaster 39999
7460 Apis mellifera 410309 7070 Tribolium castaneum 660005
9646 Ailuropoda melanoleuca ENSAMEG00000004774 9358 Choloepus hoffmanni ENSCHOG00000007152
9361 Dasypus novemcinctus ENSDNOG00000018641 9371 Echinops telfairi ENSETEG00000001775
69293 Gasterosteus aculeatus ENSGACG00000001665 8049 Gadus morhua ENSGMOG00000001375
7897 Latimeria chalumnae ENSLACG00000009212 9315 Macropus eugenii ENSMEUG00000007824
30608 Microcebus murinus ENSMICG00000016663 9978 Ochotona princeps ENSOPRG00000003439
8090 Oryzias latipes ENSORLG00000004432 9813 Procavia capensis ENSPCAG00000001034
9601 Pongo abelii ENSPPYG00000013648 13735 Pelodiscus sinensis ENSPSIG00000011100
42254 Sorex araneus ENSSARG00000009808 43179 Ictidomys tridecemlineatus ENSSTOG00000012778
59729 Taeniopygia guttata ENSTGUG00000004069 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
8364 Xenopus tropicalis ENSXETG00000017422 8083 Xiphophorus maculatus ENSXMAG00000017330
7668 Strongylocentrotus purpuratus 580686 28377 Anolis carolinensis ENSACAG00000013360
9615 Canis familiaris ENSCAFG00000004991 51511 Ciona savignyi ENSCSAVG00000003303
7955 Danio rerio ENSDARG00000031848 9365 Erinaceus europaeus ENSEEUG00000006334
9785 Loxodonta africana ENSLAFG00000030870 9544 Macaca mulatta ENSMMUG00000007191
132908 Pteropus vampyrus ENSPVAG00000009845 37347 Tupaia belangeri ENSTBEG00000011278
99883 Tetraodon nigroviridis ENSTNIG00000014805 30538 Vicugna pacos ENSVPAG00000011059