Basic Information
Gene ID 40833
Gene Name Scr; CG1030
Full Name Homeotic protein Sex combs reduced
Organism Drosophila melanogaster [7227]

Cross Reference
UniProt P09077 UniGene Dm.2481
PDB 2R5Z OMIM NULL
KEGG dme:Dmel_CG1030 UCSC NULL

Protein Interactions
DIP DIP-40017N
IntAct P09077
MINT NULL
STRING 7227.FBpp0081163

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
FBpp0081163 Gene3D G3DSA:1.10.10.60 IPR009057 319 384 3.70e-29 Homeodomain-like
FBpp0081163 Pfam PF00046 IPR001356 325 381 9.60e-22 Homeobox domain
FBpp0081163 PRINTS PR00024 IPR020479 346 357 1.20e-08 Homeodomain, metazoa
FBpp0081163 PRINTS PR00024 IPR020479 361 371 1.20e-08 Homeodomain, metazoa
FBpp0081163 PRINTS PR00024 IPR020479 371 380 1.20e-08 Homeodomain, metazoa
FBpp0081163 PRINTS PR00025 IPR017995 303 310 1.10e-05 Homeobox protein, antennapedia type
FBpp0081163 PRINTS PR00025 IPR017995 325 340 1.10e-05 Homeobox protein, antennapedia type
FBpp0081163 ProSitePatterns PS00027 IPR017970 357 380 - Homeobox, conserved site
FBpp0081163 ProSitePatterns PS00032 IPR001827 304 309 - Homeobox protein, antennapedia type, conserved site
FBpp0081163 ProSiteProfiles PS50071 IPR001356 322 382 0.00e-00 Homeobox domain
FBpp0081163 SMART SM00389 IPR001356 324 386 1.30e-28 Homeobox domain
FBpp0081163 SUPERFAMILY SSF46689 IPR009057 306 382 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
FBpp0081163 PF00046 9.6e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
FBpp0081163 GO:0006351 biological_process transcription, DNA-templated
FBpp0081163 GO:0006355 biological_process regulation of transcription, DNA-templated
FBpp0081163 GO:0007275 biological_process multicellular organismal development
FBpp0081163 GO:0005634 cellular_component nucleus
FBpp0081163 GO:0003677 molecular_function DNA binding
FBpp0081163 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
FBpp0081163 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100110095 7029 Acyrthosiphon pisum 100167267
10224 Saccoglossus kowalevskii 100303538 9785 Loxodonta africana 100677370
8128 Oreochromis niloticus 100698137 132113 Bombus impatiens 100747162
7668 Strongylocentrotus purpuratus 100888432 34638 Metaseiulus occidentalis 100902699
9305 Sarcophilus harrisii 100918823 9555 Papio anubis 101011390
9595 Gorilla gorilla 101124940 43179 Ictidomys tridecemlineatus 101974356
8083 Xiphophorus maculatus 102225798 10090 Mus musculus 15413
9606 Homo sapiens 3215 13616 Monodelphis domestica 100010060
9601 Pongo abelii 100447336 9823 Sus scrofa 100522700
61853 Nomascus leucogenys 100607908 30195 Bombus terrestris 100643224
9258 Ornithorhynchus anatinus 100681998 9615 Canis familiaris 100686000
10029 Cricetulus griseus 100774854 143995 Megachile rotundata 100877272
30611 Otolemur garnettii 100942901 9597 Pan paniscus 100993546
39432 Saimiri boliviensis 101038553 7897 Latimeria chalumnae 102360476
13735 Pelodiscus sinensis 102460897 9031 Gallus gallus 425096
7719 Ciona intestinalis 445674 7460 Apis mellifera 551506
7955 Danio rerio 58055 7070 Tribolium castaneum 641600
9913 Bos taurus 768039 9646 Ailuropoda melanoleuca ENSAMEG00000004967
10020 Dipodomys ordii ENSDORG00000006999 9365 Erinaceus europaeus ENSEEUG00000005567
9371 Echinops telfairi ENSETEG00000019368 69293 Gasterosteus aculeatus ENSGACG00000003945
8049 Gadus morhua ENSGMOG00000003194 30608 Microcebus murinus ENSMICG00000007524
9669 Mustela putorius furo ENSMPUG00000004770 9978 Ochotona princeps ENSOPRG00000000394
10116 Rattus norvegicus ENSRNOG00000045996 42254 Sorex araneus ENSSARG00000007957
59729 Taeniopygia guttata ENSTGUG00000002906 99883 Tetraodon nigroviridis ENSTNIG00000000158
9478 Tarsius syrichta ENSTSYG00000007228 30538 Vicugna pacos ENSVPAG00000005469
9598 Pan troglodytes 749212 28377 Anolis carolinensis ENSACAG00000006484
10141 Cavia porcellus ENSCPOG00000019518 51511 Ciona savignyi ENSCSAVG00000004156
9796 Equus caballus ENSECAG00000000461 59463 Myotis lucifugus ENSMLUG00000028593
9544 Macaca mulatta ENSMMUG00000013456 8090 Oryzias latipes ENSORLG00000017041
9813 Procavia capensis ENSPCAG00000006172 132908 Pteropus vampyrus ENSPVAG00000015524
31033 Takifugu rubripes ENSTRUG00000018252 9739 Tursiops truncatus ENSTTRG00000012251