Basic Information
Gene ID 4781 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NFIB
Full Name Nuclear factor 1 B-type
Organism Homo sapiens [9606]

Cross Reference
UniProt O00712 UniGene Hs.644095
PDB NULL OMIM 600728
KEGG hsa:4781 UCSC uc022bdp.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000370346

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000380711 PANTHER PTHR11492 IPR000647 1 570 0.00e-00 CTF transcription factor/nuclear factor 1
ENSP00000380711 Pfam PF00859 IPR000647 209 498 1.00e-123 CTF transcription factor/nuclear factor 1
ENSP00000380711 Pfam PF03165 IPR003619 70 171 1.50e-11 MAD homology 1, Dwarfin-type
ENSP00000380711 Pfam PF10524 IPR019548 5 47 2.80e-27 CTF transcription factor/nuclear factor 1, N-terminal
ENSP00000380711 ProSitePatterns PS00349 IPR019739 37 48 - CTF transcription factor/nuclear factor 1, conserved site
ENSP00000380711 ProSiteProfiles PS51080 IPR020604 2 195 0.00e-00 CTF transcription factor/nuclear factor 1, DNA-binding domain
ENSP00000380711 SMART SM00523 IPR003619 68 176 3.50e-22 MAD homology 1, Dwarfin-type

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000380711 PF00859 0 CTF_NFI CTF/NF-I family transcription modulation region
ENSP00000380711 PF10524 1.6e-27 NfI_DNAbd_pre-N Nuclear factor I protein pre-N-terminus
ENSP00000380711 PF03165 7.9e-12 MH1 MH1 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000380711 GO:0006260 biological_process DNA replication
ENSP00000380711 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSP00000380711 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSP00000380711 GO:0005634 cellular_component nucleus
ENSP00000380711 GO:0003677 molecular_function DNA binding
ENSP00000380711 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100118989 9823 Sus scrofa 100155995
7029 Acyrthosiphon pisum 100169415 9483 Callithrix jacchus 100397451
9646 Ailuropoda melanoleuca 100477452 400682 Amphimedon queenslandica 100636562
30195 Bombus terrestris 100645803 7463 Apis florea 100869940
143995 Megachile rotundata 100883560 7668 Strongylocentrotus purpuratus 100893750
34638 Metaseiulus occidentalis 100908516 30611 Otolemur garnettii 100966199
9595 Gorilla gorilla 101141786 59463 Myotis lucifugus 102423785
10090 Mus musculus 18028 10116 Rattus norvegicus 29227
7227 Drosophila melanogaster 43782 9615 Canis familiaris 474709
6087 Hydra magnipapillata 100211197 132113 Bombus impatiens 100746344
10029 Cricetulus griseus 100761735 9597 Pan paniscus 100983453
9555 Papio anubis 101014357 39432 Saimiri boliviensis 101047681
9669 Mustela putorius furo 101671584 7897 Latimeria chalumnae 102365155
13735 Pelodiscus sinensis 102448068 9796 Equus caballus ENSECAG00000024578
9371 Echinops telfairi ENSETEG00000016780 9685 Felis catus ENSFCAG00000008473
69293 Gasterosteus aculeatus ENSGACG00000019677 9031 Gallus gallus ENSGALG00000005441
9315 Macropus eugenii ENSMEUG00000010629 9103 Meleagris gallopavo ENSMGAG00000007634
30608 Microcebus murinus ENSMICG00000005833 61853 Nomascus leucogenys ENSNLEG00000017626
9258 Ornithorhynchus anatinus ENSOANG00000030883 9978 Ochotona princeps ENSOPRG00000000687
9813 Procavia capensis ENSPCAG00000002420 9598 Pan troglodytes ENSPTRG00000010261
42254 Sorex araneus ENSSARG00000002265 9305 Sarcophilus harrisii ENSSHAG00000015798
43179 Ictidomys tridecemlineatus ENSSTOG00000002234 59729 Taeniopygia guttata ENSTGUG00000004639
31033 Takifugu rubripes ENSTRUG00000013602 9478 Tarsius syrichta ENSTSYG00000008733
8083 Xiphophorus maculatus ENSXMAG00000008538 7955 Danio rerio 556665
7070 Tribolium castaneum 660261 9544 Macaca mulatta 714098
28377 Anolis carolinensis ENSACAG00000017798 9913 Bos taurus ENSBTAG00000027442
9358 Choloepus hoffmanni ENSCHOG00000002015 7719 Ciona intestinalis ENSCING00000002528
10141 Cavia porcellus ENSCPOG00000003925 51511 Ciona savignyi ENSCSAVG00000011360
9361 Dasypus novemcinctus ENSDNOG00000019957 10020 Dipodomys ordii ENSDORG00000004277
9365 Erinaceus europaeus ENSEEUG00000012997 8049 Gadus morhua ENSGMOG00000005260
9785 Loxodonta africana ENSLAFG00000000868 13616 Monodelphis domestica ENSMODG00000014999
9986 Oryctolagus cuniculus ENSOCUG00000004249 8128 Oreochromis niloticus ENSONIG00000013455
8090 Oryzias latipes ENSORLG00000005185 7757 Petromyzon marinus ENSPMAG00000009308
9601 Pongo abelii ENSPPYG00000019214 132908 Pteropus vampyrus ENSPVAG00000007629
37347 Tupaia belangeri ENSTBEG00000001947 99883 Tetraodon nigroviridis ENSTNIG00000011170
9739 Tursiops truncatus ENSTTRG00000010572 30538 Vicugna pacos ENSVPAG00000005804
8364 Xenopus tropicalis ENSXETG00000000835