Basic Information
Gene ID 5378 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name PMS1; PMSL1
Full Name PMS1 protein homolog 1
Organism Homo sapiens [9606]

Cross Reference
UniProt P54277 UniGene Hs.111749
PDB 2CS1 OMIM 600258
KEGG hsa:5378 UCSC uc002urk.4

Protein Interactions
DIP NULL
IntAct P54277
MINT NULL
STRING 9606.ENSP00000406490

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_000525 Gene3D G3DSA:1.10.30.10 IPR009071 571 636 1.00e-16 High mobility group box domain
NP_000525 Gene3D G3DSA:3.30.230.10 IPR014721 204 337 1.20e-28 Ribosomal protein S5 domain 2-type fold, subgroup
NP_000525 Gene3D G3DSA:3.30.565.10 IPR003594 2 203 1.40e-63 Histidine kinase-like ATPase, ATP-binding domain
NP_000525 PANTHER PTHR10073 IPR002099 1 931 0.00e-00 DNA mismatch repair protein family
NP_000525 Pfam PF00505 IPR009071 571 637 1.00e-13 High mobility group box domain
NP_000525 Pfam PF01119 IPR013507 210 336 1.60e-25 DNA mismatch repair protein, C-terminal
NP_000525 Pfam PF02518 IPR003594 18 143 1.30e-10 Histidine kinase-like ATPase, ATP-binding domain
NP_000525 ProSitePatterns PS00058 IPR014762 91 97 - DNA mismatch repair, conserved site
NP_000525 ProSiteProfiles PS50118 IPR009071 571 639 0.00e-00 High mobility group box domain
NP_000525 SMART SM00387 IPR003594 16 151 9.90e-03 Histidine kinase-like ATPase, ATP-binding domain
NP_000525 SMART SM00398 IPR009071 570 640 5.70e-25 High mobility group box domain
NP_000525 SUPERFAMILY SSF47095 IPR009071 557 636 0.00e-00 High mobility group box domain
NP_000525 SUPERFAMILY SSF54211 IPR020568 191 337 0.00e-00 Ribosomal protein S5 domain 2-type fold
NP_000525 SUPERFAMILY SSF55874 IPR003594 16 200 0.00e-00 Histidine kinase-like ATPase, ATP-binding domain
NP_000525 TIGRFAM TIGR00585 IPR002099 1 318 1.00e-99 DNA mismatch repair protein family

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_000525 PF01119 5.4e-26 DNA_mis_repair DNA mismatch repair protein, C-terminal domain
NP_000525 PF00505 1e-13 HMG_box HMG (high mobility group) box
NP_000525 PF13589 2.1e-12 HATPase_c_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NP_000525 PF02518 5.5e-11 HATPase_c Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NP_000525 PF09011 1.2e-10 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_000525 GO:0006200 biological_process ATP catabolic process
NP_000525 GO:0006298 biological_process mismatch repair
NP_000525 GO:0007131 biological_process reciprocal meiotic recombination
NP_000525 GO:0032300 cellular_component mismatch repair complex
NP_000525 GO:0032389 cellular_component MutLalpha complex
NP_000525 GO:0003697 molecular_function single-stranded DNA binding
NP_000525 GO:0005524 molecular_function ATP binding
NP_000525 GO:0016887 molecular_function ATPase activity
NP_000525 GO:0030983 molecular_function mismatched DNA binding
NP_000525 GO:0032407 molecular_function MutSalpha complex binding