Basic Information
Gene ID 54131 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Irf3
Full Name Interferon regulatory factor 3
Organism Mus musculus [10090]

Cross Reference
UniProt P70671 UniGene Mm.489648
PDB NULL OMIM NULL
KEGG mmu:54131 UCSC uc009gsm.2

Protein Interactions
DIP DIP-29881N
IntAct P70671
MINT MINT-2737174
STRING 10090.ENSMUSP00000103466

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_058545 Gene3D G3DSA:1.10.10.10 IPR011991 7 114 4.90e-37 Winged helix-turn-helix DNA-binding domain
NP_058545 Gene3D G3DSA:2.60.200.10 IPR017855 182 416 1.40e-77 SMAD domain-like
NP_058545 Pfam PF00605 IPR001346 7 110 1.90e-30 Interferon regulatory factor DNA-binding domain
NP_058545 Pfam PF10401 IPR019471 196 372 4.40e-48 Interferon regulatory factor-3
NP_058545 PRINTS PR00267 IPR001346 33 46 1.50e-17 Interferon regulatory factor DNA-binding domain
NP_058545 PRINTS PR00267 IPR001346 50 67 1.50e-17 Interferon regulatory factor DNA-binding domain
NP_058545 PRINTS PR00267 IPR001346 7 26 1.50e-17 Interferon regulatory factor DNA-binding domain
NP_058545 PRINTS PR00267 IPR001346 73 95 1.50e-17 Interferon regulatory factor DNA-binding domain
NP_058545 ProSitePatterns PS00601 IPR019817 26 58 - Interferon regulatory factor, conserved site
NP_058545 ProSiteProfiles PS51507 IPR001346 5 111 0.00e-00 Interferon regulatory factor DNA-binding domain
NP_058545 SMART SM00348 IPR001346 1 112 2.30e-52 Interferon regulatory factor DNA-binding domain
NP_058545 SUPERFAMILY SSF49879 IPR008984 185 417 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_058545 PF10401 0 IRF-3 Interferon-regulatory factor 3
NP_058545 PF00605 1.2e-30 IRF Interferon regulatory factor transcription factor

Gene Ontology Annotation
Protein Entry Name Space Description
NP_058545 GO:0006351 biological_process transcription, DNA-templated
NP_058545 GO:0005634 cellular_component nucleus
NP_058545 GO:0005737 cellular_component cytoplasm
NP_058545 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity