Basic Information
Gene ID 58158 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NEUROD4; ATH3, ATOH3, BHLHA4
Full Name Neurogenic differentiation factor 4
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9HD90 UniGene Hs.591024
PDB NULL OMIM 611635
KEGG hsa:58158 UCSC uc001sgp.4

Protein Interactions
DIP NULL
IntAct Q9HD90
MINT NULL
STRING 9606.ENSP00000242994

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000242994 Gene3D G3DSA:4.10.280.10 IPR011598 88 144 1.70e-24 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000242994 Pfam PF00010 IPR011598 88 139 1.10e-15 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000242994 Pfam PF12533 IPR022575 146 264 9.10e-44 Neurogenic differentiation factor, domain of unknown function
ENSP00000242994 PIRSF PIRSF015618 IPR016637 1 331 3.00e-225 Transcription factor, basic helix-loop-helix, NeuroD
ENSP00000242994 ProSiteProfiles PS50888 IPR011598 87 139 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000242994 SMART SM00353 IPR011598 93 145 7.60e-19 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000242994 SUPERFAMILY SSF47459 IPR011598 86 148 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000242994 PF12533 9.10844e-44 Neuro_bHLH Neuronal helix-loop-helix transcription factor
ENSP00000242994 PF00010 1.1e-15 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000242994 GO:0006351 biological_process transcription, DNA-templated
ENSP00000242994 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000242994 GO:0035881 biological_process amacrine cell differentiation
ENSP00000242994 GO:0045597 biological_process positive regulation of cell differentiation
ENSP00000242994 GO:0005634 cellular_component nucleus
ENSP00000242994 GO:0003677 molecular_function DNA binding
ENSP00000242994 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100124310 9103 Meleagris gallopavo 100542925
9785 Loxodonta africana 100677518 10141 Cavia porcellus 100724964
10029 Cricetulus griseus 100753246 9597 Pan paniscus 100993852
9555 Papio anubis 101008660 9823 Sus scrofa 100151884
61853 Nomascus leucogenys 100602311 8128 Oreochromis niloticus 100709075
39432 Saimiri boliviensis 101047841 9685 Felis catus 101095025
9595 Gorilla gorilla 101145152 9669 Mustela putorius furo 101680563
43179 Ictidomys tridecemlineatus 101961038 7897 Latimeria chalumnae 102346727
59463 Myotis lucifugus 102424444 13735 Pelodiscus sinensis 102463039
10116 Rattus norvegicus 288821 9361 Dasypus novemcinctus ENSDNOG00000009650
10020 Dipodomys ordii ENSDORG00000010174 9371 Echinops telfairi ENSETEG00000009519
69293 Gasterosteus aculeatus ENSGACG00000008952 8049 Gadus morhua ENSGMOG00000006899
30608 Microcebus murinus ENSMICG00000008491 9258 Ornithorhynchus anatinus ENSOANG00000011626
9813 Procavia capensis ENSPCAG00000002075 42254 Sorex araneus ENSSARG00000010152
99883 Tetraodon nigroviridis ENSTNIG00000002442 31033 Takifugu rubripes ENSTRUG00000013273
9478 Tarsius syrichta ENSTSYG00000003704 9739 Tursiops truncatus ENSTTRG00000016039
30538 Vicugna pacos ENSVPAG00000012065 8083 Xiphophorus maculatus ENSXMAG00000011061
9031 Gallus gallus ENSGALG00000024396 30611 Otolemur garnettii ENSOGAG00000009685
8090 Oryzias latipes ENSORLG00000007467 9601 Pongo abelii ENSPPYG00000004613
37347 Tupaia belangeri ENSTBEG00000000432