Basic Information | |||
Gene ID | 6778 ; ![]() ![]() | ||
Gene Name | STAT6 | ||
Full Name | Signal transducer and activator of transcription 6 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P42226 | UniGene | Hs.524518 |
PDB | 1OJ5 | OMIM | 601512 |
KEGG | hsa:6778 | UCSC | uc001sna.3 |
Protein Interactions | |
DIP | NULL |
IntAct | P42226 |
MINT | MINT-8020389 |
STRING | 9606.ENSP00000300134 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001171550 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 416 | 541 | 2.40e-41 | EF-hand domain pair |
NP_001171550 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 113 | 7.70e-23 | STAT transcription factor, protein interaction |
NP_001171550 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 114 | 273 | 1.30e-22 | STAT transcription factor, all-alpha |
NP_001171550 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 275 | 415 | 3.90e-43 | STAT transcription factor, DNA-binding, subdomain |
NP_001171550 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 542 | 650 | 6.70e-37 | SH2 domain |
NP_001171550 | PANTHER | PTHR11801 | IPR001217 | 2 | 718 | 0.00e-00 | Transcription factor STAT |
NP_001171550 | Pfam | PF00017 | IPR000980 | 538 | 616 | 3.70e-10 | SH2 domain |
NP_001171550 | Pfam | PF01017 | IPR013800 | 125 | 271 | 3.10e-24 | STAT transcription factor, all-alpha |
NP_001171550 | Pfam | PF02864 | IPR013801 | 273 | 527 | 1.30e-93 | STAT transcription factor, DNA-binding |
NP_001171550 | Pfam | PF02865 | IPR013799 | 2 | 115 | 9.60e-24 | STAT transcription factor, protein interaction |
NP_001171550 | Pfam | PF14596 | IPR028187 | 655 | 847 | 1.40e-114 | STAT6, C-terminal |
NP_001171550 | ProSiteProfiles | PS50001 | IPR000980 | 517 | 632 | 0.00e-00 | SH2 domain |
NP_001171550 | SMART | SM00252 | IPR000980 | 540 | 622 | 1.60e-07 | SH2 domain |
NP_001171550 | SMART | SM00964 | IPR013799 | 2 | 116 | 2.70e-41 | STAT transcription factor, protein interaction |
NP_001171550 | SUPERFAMILY | SSF47655 | IPR015988 | 112 | 273 | 0.00e-00 | STAT transcription factor, coiled coil |
NP_001171550 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 115 | 0.00e-00 | STAT transcription factor, protein interaction |
NP_001171550 | SUPERFAMILY | SSF49417 | IPR008967 | 265 | 528 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001171550 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
NP_001171550 | PF14596 | 0 | STAT6_C | STAT6 C-terminal |
NP_001171550 | PF01017 | 3.4e-26 | STAT_alpha | STAT protein, all-alpha domain |
NP_001171550 | PF02865 | 2.6e-24 | STAT_int | STAT protein, protein interaction domain |
NP_001171550 | PF00017 | 1.7e-10 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001171550 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
NP_001171550 | GO:0005634 | cellular_component | nucleus |
NP_001171550 | GO:0005737 | cellular_component | cytoplasm |
NP_001171550 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001171550 | GO:0004871 | molecular_function | signal transducer activity |
NP_001171550 | GO:0005509 | molecular_function | calcium ion binding |