Basic Information
Gene ID 711355
Gene Name SMAD3
Full Name Mothers against decapentaplegic homolog 3 isoform 1
Organism Macaca mulatta [9544]

Cross Reference
UniProt F6QB58 UniGene Mmu.33387
PDB NULL OMIM NULL
KEGG mcc:711355 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000020271 Gene3D G3DSA:2.60.200.10 IPR017855 224 425 8.10e-99 SMAD domain-like
ENSMMUP00000020271 Gene3D G3DSA:3.90.520.10 IPR013019 2 143 3.90e-65 MAD homology, MH1
ENSMMUP00000020271 PANTHER PTHR13703 IPR013790 1 425 0.00e-00 Dwarfin
ENSMMUP00000020271 Pfam PF03165 IPR003619 31 131 6.40e-44 MAD homology 1, Dwarfin-type
ENSMMUP00000020271 Pfam PF03166 IPR001132 227 402 2.20e-77 SMAD domain, Dwarfin-type
ENSMMUP00000020271 ProSiteProfiles PS51075 IPR013019 10 136 0.00e-00 MAD homology, MH1
ENSMMUP00000020271 ProSiteProfiles PS51076 IPR001132 232 425 0.00e-00 SMAD domain, Dwarfin-type
ENSMMUP00000020271 SMART SM00523 IPR003619 26 134 9.50e-71 MAD homology 1, Dwarfin-type
ENSMMUP00000020271 SMART SM00524 IPR001132 230 401 1.40e-111 SMAD domain, Dwarfin-type
ENSMMUP00000020271 SUPERFAMILY SSF49879 IPR008984 176 416 0.00e-00 SMAD/FHA domain
ENSMMUP00000020271 SUPERFAMILY SSF56366 IPR013019 10 131 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000020271 PF03166 0 MH2 MH2 domain
ENSMMUP00000020271 PF03165 3.22299e-44 MH1 MH1 domain
ENSMMUP00000020271 PF10401 6.5e-05 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000020271 GO:0006351 biological_process transcription, DNA-templated
ENSMMUP00000020271 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSMMUP00000020271 GO:0005634 cellular_component nucleus
ENSMMUP00000020271 GO:0005667 cellular_component transcription factor complex
ENSMMUP00000020271 GO:0005737 cellular_component cytoplasm
ENSMMUP00000020271 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100114895 10224 Saccoglossus kowalevskii 100313734
9601 Pongo abelii 100448249 34638 Metaseiulus occidentalis 100906659
9597 Pan paniscus 100993322 43179 Ictidomys tridecemlineatus 101973097
10116 Rattus norvegicus 25631 7668 Strongylocentrotus purpuratus 577345
7955 Danio rerio 58092 9483 Callithrix jacchus 100393808
30195 Bombus terrestris 100646575 132113 Bombus impatiens 100740756
7463 Apis florea 100864028 143995 Megachile rotundata 100882571
9555 Papio anubis 101013089 39432 Saimiri boliviensis 101039593
7460 Apis mellifera 412601 7719 Ciona intestinalis 778756
9913 Bos taurus ENSBTAG00000012599 9615 Canis familiaris ENSCAFG00000017388
51511 Ciona savignyi ENSCSAVG00000004749 69293 Gasterosteus aculeatus ENSGACG00000005092
8049 Gadus morhua ENSGMOG00000008364 9785 Loxodonta africana ENSLAFG00000021903
13616 Monodelphis domestica ENSMODG00000009609 61853 Nomascus leucogenys ENSNLEG00000012983
8128 Oreochromis niloticus ENSONIG00000013271 9978 Ochotona princeps ENSOPRG00000014996
99883 Tetraodon nigroviridis ENSTNIG00000009546 31033 Takifugu rubripes ENSTRUG00000016858
9598 Pan troglodytes 748161 28377 Anolis carolinensis ENSACAG00000009914
9646 Ailuropoda melanoleuca ENSAMEG00000003318 9358 Choloepus hoffmanni ENSCHOG00000001562
10141 Cavia porcellus ENSCPOG00000021314 9371 Echinops telfairi ENSETEG00000003356
9315 Macropus eugenii ENSMEUG00000016668 9103 Meleagris gallopavo ENSMGAG00000009879
30608 Microcebus murinus ENSMICG00000006119 9258 Ornithorhynchus anatinus ENSOANG00000013558
8090 Oryzias latipes ENSORLG00000002207 9813 Procavia capensis ENSPCAG00000008103
7757 Petromyzon marinus ENSPMAG00000000489 132908 Pteropus vampyrus ENSPVAG00000002626
9305 Sarcophilus harrisii ENSSHAG00000012543 8083 Xiphophorus maculatus ENSXMAG00000002377

Paralogs
697581