Basic Information
Gene ID 712645
Gene Name SMAD5
Full Name Mothers against decapentaplegic homolog 5
Organism Macaca mulatta [9544]

Cross Reference
UniProt F6YMS3 UniGene Mmu.32164
PDB NULL OMIM NULL
KEGG mcc:712645 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000000461 Gene3D G3DSA:2.60.200.10 IPR017855 263 465 6.50e-97 SMAD domain-like
ENSMMUP00000000461 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 8.60e-62 MAD homology, MH1
ENSMMUP00000000461 PANTHER PTHR13703 IPR013790 1 465 0.00e-00 Dwarfin
ENSMMUP00000000461 Pfam PF03165 IPR003619 32 132 4.80e-42 MAD homology 1, Dwarfin-type
ENSMMUP00000000461 Pfam PF03166 IPR001132 266 442 7.40e-78 SMAD domain, Dwarfin-type
ENSMMUP00000000461 ProSiteProfiles PS51075 IPR013019 13 137 0.00e-00 MAD homology, MH1
ENSMMUP00000000461 ProSiteProfiles PS51076 IPR001132 271 465 0.00e-00 SMAD domain, Dwarfin-type
ENSMMUP00000000461 SMART SM00523 IPR003619 26 135 4.80e-71 MAD homology 1, Dwarfin-type
ENSMMUP00000000461 SMART SM00524 IPR001132 269 441 2.50e-108 SMAD domain, Dwarfin-type
ENSMMUP00000000461 SUPERFAMILY SSF49879 IPR008984 235 456 0.00e-00 SMAD/FHA domain
ENSMMUP00000000461 SUPERFAMILY SSF56366 IPR013019 14 132 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000000461 PF03166 0 MH2 MH2 domain
ENSMMUP00000000461 PF03165 2.29953e-42 MH1 MH1 domain
ENSMMUP00000000461 PF10401 1.1e-06 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000000461 GO:0001657 biological_process ureteric bud development
ENSMMUP00000000461 GO:0002051 biological_process osteoblast fate commitment
ENSMMUP00000000461 GO:0006351 biological_process transcription, DNA-templated
ENSMMUP00000000461 GO:0006468 biological_process protein phosphorylation
ENSMMUP00000000461 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSMMUP00000000461 GO:0030509 biological_process BMP signaling pathway
ENSMMUP00000000461 GO:0045669 biological_process positive regulation of osteoblast differentiation
ENSMMUP00000000461 GO:0051216 biological_process cartilage development
ENSMMUP00000000461 GO:0060348 biological_process bone development
ENSMMUP00000000461 GO:0071773 biological_process cellular response to BMP stimulus
ENSMMUP00000000461 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
ENSMMUP00000000461 GO:0005634 cellular_component nucleus
ENSMMUP00000000461 GO:0005667 cellular_component transcription factor complex
ENSMMUP00000000461 GO:0005737 cellular_component cytoplasm
ENSMMUP00000000461 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
ENSMMUP00000000461 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMMUP00000000461 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
6087 Hydra magnipapillata 100211577 61853 Nomascus leucogenys 100580616
10029 Cricetulus griseus 100754116 31033 Takifugu rubripes 101064562
10090 Mus musculus 17129 13616 Monodelphis domestica 100011974
9258 Ornithorhynchus anatinus 100089852 7425 Nasonia vitripennis 100116381
9986 Oryctolagus cuniculus 100342616 9646 Ailuropoda melanoleuca 100467794
9103 Meleagris gallopavo 100542490 28377 Anolis carolinensis 100564659
8128 Oreochromis niloticus 100706145 10141 Cavia porcellus 100717571
9597 Pan paniscus 100969842 39432 Saimiri boliviensis 101050360
9685 Felis catus 101081602 9595 Gorilla gorilla 101137217
9669 Mustela putorius furo 101687381 43179 Ictidomys tridecemlineatus 101974404
9913 Bos taurus 768050 9483 Callithrix jacchus ENSCJAG00000005968
9361 Dasypus novemcinctus ENSDNOG00000006004 10020 Dipodomys ordii ENSDORG00000004533
9365 Erinaceus europaeus ENSEEUG00000001684 9371 Echinops telfairi ENSETEG00000019912
9606 Homo sapiens ENSG00000113658 8049 Gadus morhua ENSGMOG00000005788
9315 Macropus eugenii ENSMEUG00000005813 59463 Myotis lucifugus ENSMLUG00000002321
9978 Ochotona princeps ENSOPRG00000010102 9813 Procavia capensis ENSPCAG00000006817
13735 Pelodiscus sinensis ENSPSIG00000003731 132908 Pteropus vampyrus ENSPVAG00000016214
42254 Sorex araneus ENSSARG00000009234 9823 Sus scrofa ENSSSCG00000025920
59729 Taeniopygia guttata ENSTGUG00000001214 9739 Tursiops truncatus ENSTTRG00000016274
30538 Vicugna pacos ENSVPAG00000007328 8083 Xiphophorus maculatus ENSXMAG00000016280
69293 Gasterosteus aculeatus ENSGACG00000018718 9305 Sarcophilus harrisii ENSSHAG00000006806
9478 Tarsius syrichta ENSTSYG00000005318

Paralogs
574340 694572