Basic Information | |||
Gene ID | 716170 | ||
Gene Name | TP53; P53 | ||
Full Name | Cellular tumor antigen p53 | ||
Organism | Macaca mulatta [9544] |
Cross Reference | |||
UniProt | P56424 | UniGene | Mmu.3286 |
PDB | NULL | OMIM | NULL |
KEGG | mcc:716170 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | 9544.ENSMMUP00000035274 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_001040616 | Gene3D | G3DSA:2.60.40.720 | IPR012346 | 94 | 297 | 3.00e-96 | p53/RUNT-type transcription factor, DNA-binding domain |
NP_001040616 | Gene3D | G3DSA:4.10.170.10 | IPR010991 | 319 | 359 | 1.90e-21 | p53, tetramerisation domain |
NP_001040616 | PANTHER | PTHR11447 | IPR002117 | 1 | 393 | 0.00e-00 | p53 tumour suppressor family |
NP_001040616 | Pfam | PF00870 | IPR011615 | 95 | 288 | 2.30e-109 | p53, DNA-binding domain |
NP_001040616 | Pfam | PF07710 | IPR010991 | 318 | 358 | 1.00e-19 | p53, tetramerisation domain |
NP_001040616 | Pfam | PF08563 | IPR013872 | 6 | 29 | 1.50e-10 | p53 transactivation domain |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 116 | 142 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 158 | 179 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 213 | 234 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 236 | 258 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 264 | 286 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | PRINTS | PR00386 | IPR002117 | 326 | 350 | 6.00e-87 | p53 tumour suppressor family |
NP_001040616 | ProSitePatterns | PS00348 | IPR002117 | 237 | 249 | - | p53 tumour suppressor family |
NP_001040616 | SUPERFAMILY | SSF47719 | IPR010991 | 319 | 357 | 0.00e-00 | p53, tetramerisation domain |
NP_001040616 | SUPERFAMILY | SSF49417 | IPR008967 | 97 | 287 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_001040616 | PF00870 | 0 | P53 | P53 DNA-binding domain |
NP_001040616 | PF07710 | 5.3e-20 | P53_tetramer | P53 tetramerisation motif |
NP_001040616 | PF08563 | 6.4e-11 | P53_TAD | P53 transactivation motif |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_001040616 | GO:0000733 | biological_process | DNA strand renaturation |
NP_001040616 | GO:0006289 | biological_process | nucleotide-excision repair |
NP_001040616 | GO:0006351 | biological_process | transcription, DNA-templated |
NP_001040616 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
NP_001040616 | GO:0006915 | biological_process | apoptotic process |
NP_001040616 | GO:0007049 | biological_process | cell cycle |
NP_001040616 | GO:0007275 | biological_process | multicellular organismal development |
NP_001040616 | GO:0007569 | biological_process | cell aging |
NP_001040616 | GO:0012501 | biological_process | programmed cell death |
NP_001040616 | GO:0030308 | biological_process | negative regulation of cell growth |
NP_001040616 | GO:0051262 | biological_process | protein tetramerization |
NP_001040616 | GO:0090200 | biological_process | positive regulation of release of cytochrome c from mitochondria |
NP_001040616 | GO:0097252 | biological_process | oligodendrocyte apoptotic process |
NP_001040616 | GO:0005634 | cellular_component | nucleus |
NP_001040616 | GO:0005730 | cellular_component | nucleolus |
NP_001040616 | GO:0005737 | cellular_component | cytoplasm |
NP_001040616 | GO:0005739 | cellular_component | mitochondrion |
NP_001040616 | GO:0005759 | cellular_component | mitochondrial matrix |
NP_001040616 | GO:0005783 | cellular_component | endoplasmic reticulum |
NP_001040616 | GO:0003677 | molecular_function | DNA binding |
NP_001040616 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_001040616 | GO:0005507 | molecular_function | copper ion binding |
NP_001040616 | GO:0005524 | molecular_function | ATP binding |
NP_001040616 | GO:0044212 | molecular_function | transcription regulatory region DNA binding |
NP_001040616 | GO:0046872 | molecular_function | metal ion binding |