Basic Information
Gene ID 7594 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name ZNF43; KOX27, ZNF39, ZNF39L1
Full Name Zinc finger protein 43
Organism Homo sapiens [9606]

Cross Reference
UniProt P17038 UniGene Hs.534365
PDB NULL OMIM 603972
KEGG hsa:7594 UCSC uc002nqj.4

Protein Interactions
DIP NULL
IntAct NULL
MINT MINT-2801356
STRING 9606.ENSP00000347045

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 148 175 4.70e-05 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 176 197 3.40e-08 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 203 231 2.40e-12 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 232 259 8.90e-12 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 260 287 2.40e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 288 315 3.80e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 316 342 3.90e-20 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 343 368 6.80e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 369 399 1.50e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 400 427 6.10e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 428 455 4.70e-20 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 456 483 8.00e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 484 511 2.30e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 512 539 7.80e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 540 566 1.50e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 567 592 4.80e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 593 623 1.40e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 624 651 7.70e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 652 679 1.60e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 680 707 6.90e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 708 735 1.90e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 736 763 8.40e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Gene3D G3DSA:3.30.160.60 IPR013087 764 791 2.30e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000465732 Pfam PF01352 IPR001909 4 44 6.00e-20 Krueppel-associated box
ENSP00000465732 ProSitePatterns PS00028 IPR007087 176 196 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 288 308 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 316 336 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 344 364 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 372 392 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 400 420 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 428 448 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 456 476 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 484 504 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 512 532 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 540 560 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 568 588 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 596 616 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 624 644 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 652 672 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 680 700 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 708 728 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 736 756 - Zinc finger, C2H2
ENSP00000465732 ProSitePatterns PS00028 IPR007087 764 784 - Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 174 197 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 202 229 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 230 257 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 258 285 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 286 313 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 314 341 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 342 369 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 370 397 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 398 425 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 426 453 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 454 481 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 482 509 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 510 537 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 538 565 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 566 593 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 594 621 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 622 649 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 650 677 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 678 705 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 706 733 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 734 761 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50157 IPR007087 762 789 0.00e-00 Zinc finger, C2H2
ENSP00000465732 ProSiteProfiles PS50805 IPR001909 4 75 0.00e-00 Krueppel-associated box
ENSP00000465732 SMART SM00349 IPR001909 4 64 1.50e-38 Krueppel-associated box
ENSP00000465732 SMART SM00355 IPR015880 174 196 5.90e-05 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 202 222 5.20e-01 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 230 250 2.30e-02 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 258 278 9.90e-02 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 286 308 3.30e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 314 336 3.10e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 342 364 1.10e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 370 392 7.70e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 398 420 2.00e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 426 448 9.20e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 454 476 6.10e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 482 504 3.10e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 510 532 2.30e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 538 560 7.30e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 566 588 6.30e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 594 616 6.30e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 622 644 3.10e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 650 672 2.30e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 678 700 3.30e-05 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 706 728 3.90e-07 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 734 756 1.40e-06 Zinc finger, C2H2-like
ENSP00000465732 SMART SM00355 IPR015880 762 784 1.60e-06 Zinc finger, C2H2-like
ENSP00000465732 SUPERFAMILY SSF109640 IPR001909 2 59 0.00e-00 Krueppel-associated box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000465732 PF00096 0 zf-C2H2 Zinc finger, C2H2 type
ENSP00000465732 PF13465 0 zf-H2C2_2 Zinc-finger double domain
ENSP00000465732 PF13894 0 zf-C2H2_4 C2H2-type zinc finger
ENSP00000465732 PF13912 0 zf-C2H2_6 C2H2-type zinc finger
ENSP00000465732 PF09723 1.1e-21 Zn-ribbon_8 Zinc ribbon domain
ENSP00000465732 PF12171 2e-21 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
ENSP00000465732 PF01352 2.5e-20 KRAB KRAB box
ENSP00000465732 PF01286 3.4e-08 XPA_N XPA protein N-terminal
ENSP00000465732 PF07649 5.2e-07 C1_3 C1-like domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000465732 GO:0006351 biological_process transcription, DNA-templated
ENSP00000465732 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000465732 GO:0005634 cellular_component nucleus
ENSP00000465732 GO:0003677 molecular_function DNA binding
ENSP00000465732 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000465732 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9544 Macaca mulatta 100430377 61853 Nomascus leucogenys 100581461
9597 Pan paniscus 100970298 9555 Papio anubis 101016655
9595 Gorilla gorilla ENSGGOG00000006734 9598 Pan troglodytes ENSPTRG00000029066

Paralogs
100129543 163227 199777 51351
57615 7562 100129842 170959
ENSG00000160229 ENSG00000262037 ENSG00000196081