Basic Information
Gene ID 83439 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name TCF7L1; TCF3
Full Name Transcription factor 7-like 1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9HCS4 UniGene Hs.516297
PDB NULL OMIM 604652
KEGG hsa:83439 UCSC uc002soy.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000282111

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_112573 Gene3D G3DSA:1.10.30.10 IPR009071 344 426 4.30e-27 High mobility group box domain
NP_112573 Gene3D G3DSA:4.10.900.10 IPR027397 1 81 7.40e-18 Catenin binding domain
NP_112573 PANTHER PTHR10373 IPR024940 11 588 0.00e-00 Transcription factor TCF/LEF
NP_112573 PANTHER PTHR10373:SF29 IPR028776 11 588 0.00e-00 Transcription factor 7-like 1, mammalian-type
NP_112573 Pfam PF00505 IPR009071 346 413 4.40e-21 High mobility group box domain
NP_112573 Pfam PF08347 IPR013558 26 250 7.50e-74 CTNNB1 binding, N-teminal
NP_112573 ProSiteProfiles PS50118 IPR009071 346 414 0.00e-00 High mobility group box domain
NP_112573 SMART SM00398 IPR009071 345 415 2.10e-23 High mobility group box domain
NP_112573 SUPERFAMILY SSF47095 IPR009071 345 426 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_112573 PF08347 0 CTNNB1_binding N-terminal CTNNB1 binding
NP_112573 PF00505 2.3e-21 HMG_box HMG (high mobility group) box
NP_112573 PF09011 2.7e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
NP_112573 GO:0006351 biological_process transcription, DNA-templated
NP_112573 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_112573 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
NP_112573 GO:0007275 biological_process multicellular organismal development
NP_112573 GO:0016055 biological_process Wnt signaling pathway
NP_112573 GO:0060070 biological_process canonical Wnt signaling pathway
NP_112573 GO:0005634 cellular_component nucleus
NP_112573 GO:0003677 molecular_function DNA binding
NP_112573 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_112573 GO:0008013 molecular_function beta-catenin binding