Basic Information
Gene ID ENSGALG00000010005
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Gallus gallus [9031]

Cross Reference
UniProt F1NG41 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000016234 Pfam PF08778 IPR014887 820 859 2.10e-20 HIF-1 alpha, transactivation domain, C-terminal
ENSGALP00000016234 Pfam PF11413 IPR021537 508 540 8.40e-18 Hypoxia-inducible factor, alpha subunit
ENSGALP00000016234 PRINTS PR00785 IPR001067 234 251 1.70e-06 Nuclear translocator
ENSGALP00000016234 PRINTS PR00785 IPR001067 41 61 1.70e-06 Nuclear translocator
ENSGALP00000016234 PRINTS PR00785 IPR001067 93 112 1.70e-06 Nuclear translocator
ENSGALP00000016234 ProSiteProfiles PS50112 IPR000014 240 291 0.00e-00 PAS domain
ENSGALP00000016234 ProSiteProfiles PS50112 IPR000014 84 139 0.00e-00 PAS domain
ENSGALP00000016234 ProSiteProfiles PS50888 IPR011598 6 59 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGALP00000016234 SMART SM00086 IPR001610 295 338 1.10e-11 PAC motif
ENSGALP00000016234 SMART SM00091 IPR000014 223 289 1.60e-10 PAS domain
ENSGALP00000016234 SMART SM00091 IPR000014 78 144 6.90e-11 PAS domain
ENSGALP00000016234 SMART SM00353 IPR011598 12 67 1.00e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGALP00000016234 SUPERFAMILY SSF47459 IPR011598 3 62 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSGALP00000016234 SUPERFAMILY SSF55785 IPR000014 235 337 0.00e-00 PAS domain
ENSGALP00000016234 SUPERFAMILY SSF55785 IPR000014 87 191 0.00e-00 PAS domain
ENSGALP00000016234 TIGRFAM TIGR00229 IPR000014 242 319 3.60e-08 PAS domain
ENSGALP00000016234 TIGRFAM TIGR00229 IPR000014 90 142 1.50e-05 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000016234 PF14598 2.8e-27 PAS_11 PAS domain
ENSGALP00000016234 PF08447 7.6e-26 PAS_3 PAS fold
ENSGALP00000016234 PF08778 8e-21 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSGALP00000016234 PF11413 2.6e-18 HIF-1 Hypoxia-inducible factor-1
ENSGALP00000016234 PF00989 6.8e-14 PAS PAS fold
ENSGALP00000016234 PF13426 1.7e-11 PAS_9 PAS domain
ENSGALP00000016234 PF08448 1.8e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000016234 GO:0001666 biological_process response to hypoxia
ENSGALP00000016234 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSGALP00000016234 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSGALP00000016234 GO:0071456 biological_process cellular response to hypoxia
ENSGALP00000016234 GO:0005634 cellular_component nucleus
ENSGALP00000016234 GO:0005737 cellular_component cytoplasm
ENSGALP00000016234 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGALP00000016234 GO:0004871 molecular_function signal transducer activity
ENSGALP00000016234 GO:0035035 molecular_function histone acetyltransferase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100396711 7897 Latimeria chalumnae 102357464
13735 Pelodiscus sinensis 102453156 9606 Homo sapiens 2034
9646 Ailuropoda melanoleuca ENSAMEG00000006020 9913 Bos taurus ENSBTAG00000003711
9615 Canis familiaris ENSCAFG00000002627 9358 Choloepus hoffmanni ENSCHOG00000005351
9361 Dasypus novemcinctus ENSDNOG00000005938 9796 Equus caballus ENSECAG00000014594
9365 Erinaceus europaeus ENSEEUG00000012802 9685 Felis catus ENSFCAG00000013629
69293 Gasterosteus aculeatus ENSGACG00000011414 9597 Pan paniscus 100975248
39432 Saimiri boliviensis 101052563 9669 Mustela putorius furo 101679355
10141 Cavia porcellus ENSCPOG00000014242 7955 Danio rerio ENSDARG00000057671
10020 Dipodomys ordii ENSDORG00000003635 9785 Loxodonta africana ENSLAFG00000012361
9103 Meleagris gallopavo ENSMGAG00000010293 59463 Myotis lucifugus ENSMLUG00000007093
9258 Ornithorhynchus anatinus ENSOANG00000015360 30611 Otolemur garnettii ENSOGAG00000008084
9978 Ochotona princeps ENSOPRG00000010205 9813 Procavia capensis ENSPCAG00000014714
7757 Petromyzon marinus ENSPMAG00000009272 132908 Pteropus vampyrus ENSPVAG00000011259
10116 Rattus norvegicus ENSRNOG00000021318 43179 Ictidomys tridecemlineatus ENSSTOG00000012628
37347 Tupaia belangeri ENSTBEG00000004645 59729 Taeniopygia guttata ENSTGUG00000003933
31033 Takifugu rubripes ENSTRUG00000005627 9478 Tarsius syrichta ENSTSYG00000001312
9739 Tursiops truncatus ENSTTRG00000011883 8364 Xenopus tropicalis ENSXETG00000026167
8083 Xiphophorus maculatus ENSXMAG00000004970 8049 Gadus morhua ENSGMOG00000016337
9315 Macropus eugenii ENSMEUG00000004035 30608 Microcebus murinus ENSMICG00000002949
9544 Macaca mulatta ENSMMUG00000023326 13616 Monodelphis domestica ENSMODG00000000953
9986 Oryctolagus cuniculus ENSOCUG00000014904 9823 Sus scrofa ENSSSCG00000008443
99883 Tetraodon nigroviridis ENSTNIG00000009866