Basic Information
Gene ID ENSMLUG00000012050
Gene Name STAT5B
Full Name Signal transducer and activator of transcription
Organism Myotis lucifugus [59463]

Cross Reference
UniProt G1PJQ0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMLUP00000010987 Gene3D G3DSA:1.10.238.10 IPR011992 473 598 2.60e-47 EF-hand domain pair
ENSMLUP00000010987 Gene3D G3DSA:1.10.532.10 IPR013799 2 126 2.40e-48 STAT transcription factor, protein interaction
ENSMLUP00000010987 Gene3D G3DSA:1.20.1050.20 IPR013800 140 333 2.40e-65 STAT transcription factor, all-alpha
ENSMLUP00000010987 Gene3D G3DSA:2.60.40.630 IPR012345 334 472 3.60e-69 STAT transcription factor, DNA-binding, subdomain
ENSMLUP00000010987 Gene3D G3DSA:3.30.505.10 IPR000980 599 713 1.80e-40 SH2 domain
ENSMLUP00000010987 PANTHER PTHR11801 IPR001217 3 779 0.00e-00 Transcription factor STAT
ENSMLUP00000010987 Pfam PF00017 IPR000980 596 664 2.40e-10 SH2 domain
ENSMLUP00000010987 Pfam PF01017 IPR013800 139 331 5.00e-55 STAT transcription factor, all-alpha
ENSMLUP00000010987 Pfam PF02864 IPR013801 333 584 4.40e-99 STAT transcription factor, DNA-binding
ENSMLUP00000010987 Pfam PF02865 IPR013799 3 126 2.20e-47 STAT transcription factor, protein interaction
ENSMLUP00000010987 ProSiteProfiles PS50001 IPR000980 590 687 0.00e-00 SH2 domain
ENSMLUP00000010987 SMART SM00252 IPR000980 588 706 8.30e-08 SH2 domain
ENSMLUP00000010987 SMART SM00964 IPR013799 3 127 7.50e-66 STAT transcription factor, protein interaction
ENSMLUP00000010987 SUPERFAMILY SSF47655 IPR015988 137 333 0.00e-00 STAT transcription factor, coiled coil
ENSMLUP00000010987 SUPERFAMILY SSF48092 IPR013799 2 125 0.00e-00 STAT transcription factor, protein interaction
ENSMLUP00000010987 SUPERFAMILY SSF49417 IPR008967 328 585 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMLUP00000010987 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSMLUP00000010987 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSMLUP00000010987 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSMLUP00000010987 PF00017 1.5e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMLUP00000010987 GO:0001553 biological_process luteinization
ENSMLUP00000010987 GO:0001779 biological_process natural killer cell differentiation
ENSMLUP00000010987 GO:0006351 biological_process transcription, DNA-templated
ENSMLUP00000010987 GO:0007259 biological_process JAK-STAT cascade
ENSMLUP00000010987 GO:0007565 biological_process female pregnancy
ENSMLUP00000010987 GO:0007595 biological_process lactation
ENSMLUP00000010987 GO:0019218 biological_process regulation of steroid metabolic process
ENSMLUP00000010987 GO:0019915 biological_process lipid storage
ENSMLUP00000010987 GO:0030155 biological_process regulation of cell adhesion
ENSMLUP00000010987 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSMLUP00000010987 GO:0038161 biological_process prolactin signaling pathway
ENSMLUP00000010987 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSMLUP00000010987 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSMLUP00000010987 GO:0043029 biological_process T cell homeostasis
ENSMLUP00000010987 GO:0043066 biological_process negative regulation of apoptotic process
ENSMLUP00000010987 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSMLUP00000010987 GO:0045579 biological_process positive regulation of B cell differentiation
ENSMLUP00000010987 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSMLUP00000010987 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSMLUP00000010987 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMLUP00000010987 GO:0046543 biological_process development of secondary female sexual characteristics
ENSMLUP00000010987 GO:0050729 biological_process positive regulation of inflammatory response
ENSMLUP00000010987 GO:0005634 cellular_component nucleus
ENSMLUP00000010987 GO:0005737 cellular_component cytoplasm
ENSMLUP00000010987 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMLUP00000010987 GO:0004871 molecular_function signal transducer activity
ENSMLUP00000010987 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7425 Nasonia vitripennis 100121885
6087 Hydra magnipapillata 100206878 9601 Pongo abelii 100462537
30195 Bombus terrestris 100647789 132113 Bombus impatiens 100743540
9597 Pan paniscus 100989105 39432 Saimiri boliviensis 101043203
9031 Gallus gallus 395556 7227 Drosophila melanogaster 42428
7668 Strongylocentrotus purpuratus 576433 9615 Canis familiaris ENSCAFG00000015509
9361 Dasypus novemcinctus ENSDNOG00000007398 9685 Felis catus ENSFCAG00000028112
8049 Gadus morhua ENSGMOG00000014154 7897 Latimeria chalumnae ENSLACG00000002646
9103 Meleagris gallopavo ENSMGAG00000003430 30608 Microcebus murinus ENSMICG00000011988
9986 Oryctolagus cuniculus 100348267 400682 Amphimedon queenslandica 100641588
7463 Apis florea 100864112 143995 Megachile rotundata 100880948
34638 Metaseiulus occidentalis 100904925 9555 Papio anubis 101000002
10090 Mus musculus 20851 10116 Rattus norvegicus 25126
9823 Sus scrofa 397340 7460 Apis mellifera 413742
7070 Tribolium castaneum 657965 9646 Ailuropoda melanoleuca ENSAMEG00000006061
9358 Choloepus hoffmanni ENSCHOG00000005387 10141 Cavia porcellus ENSCPOG00000026466
7955 Danio rerio ENSDARG00000019392 9796 Equus caballus ENSECAG00000007847
69293 Gasterosteus aculeatus ENSGACG00000008634 9595 Gorilla gorilla ENSGGOG00000008216
9978 Ochotona princeps ENSOPRG00000008312 13735 Pelodiscus sinensis ENSPSIG00000015138
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 99883 Tetraodon nigroviridis ENSTNIG00000011707
31033 Takifugu rubripes ENSTRUG00000015454 30538 Vicugna pacos ENSVPAG00000005450
61853 Nomascus leucogenys ENSNLEG00000011444 9258 Ornithorhynchus anatinus ENSOANG00000006496
8128 Oreochromis niloticus ENSONIG00000007261 8090 Oryzias latipes ENSORLG00000003961
132908 Pteropus vampyrus ENSPVAG00000003876 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 9739 Tursiops truncatus ENSTTRG00000006684
8364 Xenopus tropicalis ENSXETG00000000836

Paralogs
102423996