Basic Information
Gene ID ENSOGAG00000003838
Gene Name TP63
Full Name Uncharacterized protein
Organism Otolemur garnettii [30611]

Cross Reference
UniProt H0WNK7 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOGAP00000003415 Gene3D G3DSA:1.10.150.50 IPR013761 444 507 1.40e-33 Sterile alpha motif/pointed domain
ENSOGAP00000003415 Gene3D G3DSA:2.60.40.720 IPR012346 69 270 2.90e-101 p53/RUNT-type transcription factor, DNA-binding domain
ENSOGAP00000003415 Gene3D G3DSA:4.10.170.10 IPR010991 295 336 3.90e-22 p53, tetramerisation domain
ENSOGAP00000003415 PANTHER PTHR11447 IPR002117 16 583 0.00e-00 p53 tumour suppressor family
ENSOGAP00000003415 Pfam PF00870 IPR011615 71 265 1.10e-107 p53, DNA-binding domain
ENSOGAP00000003415 Pfam PF07647 IPR011510 444 507 7.50e-10 Sterile alpha motif, type 2
ENSOGAP00000003415 Pfam PF07710 IPR010991 294 334 5.30e-18 p53, tetramerisation domain
ENSOGAP00000003415 PRINTS PR00386 IPR002117 133 154 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 PRINTS PR00386 IPR002117 190 211 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 PRINTS PR00386 IPR002117 213 235 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 PRINTS PR00386 IPR002117 241 263 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 PRINTS PR00386 IPR002117 302 326 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 PRINTS PR00386 IPR002117 91 117 1.90e-80 p53 tumour suppressor family
ENSOGAP00000003415 ProSitePatterns PS00348 IPR002117 214 226 - p53 tumour suppressor family
ENSOGAP00000003415 SMART SM00454 IPR001660 444 510 6.30e-10 Sterile alpha motif domain
ENSOGAP00000003415 SUPERFAMILY SSF47719 IPR010991 295 335 0.00e-00 p53, tetramerisation domain
ENSOGAP00000003415 SUPERFAMILY SSF47769 IPR013761 447 512 0.00e-00 Sterile alpha motif/pointed domain
ENSOGAP00000003415 SUPERFAMILY SSF49417 IPR008967 72 263 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOGAP00000003415 PF00870 0 P53 P53 DNA-binding domain
ENSOGAP00000003415 PF07710 3e-18 P53_tetramer P53 tetramerisation motif
ENSOGAP00000003415 PF07647 4e-10 SAM_2 SAM domain (Sterile alpha motif)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOGAP00000003415 GO:0006351 biological_process transcription, DNA-templated
ENSOGAP00000003415 GO:0006915 biological_process apoptotic process
ENSOGAP00000003415 GO:0051262 biological_process protein tetramerization
ENSOGAP00000003415 GO:0005634 cellular_component nucleus
ENSOGAP00000003415 GO:0005737 cellular_component cytoplasm
ENSOGAP00000003415 GO:0003677 molecular_function DNA binding
ENSOGAP00000003415 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOGAP00000003415 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSOGAP00000003415 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116126 30195 Bombus terrestris 100648488
9785 Loxodonta africana 100657932 132113 Bombus impatiens 100748472
7463 Apis florea 100862994 9597 Pan paniscus 100988073
7955 Danio rerio 368221 9544 Macaca mulatta 703997
7668 Strongylocentrotus purpuratus 756859 9646 Ailuropoda melanoleuca ENSAMEG00000000763
7719 Ciona intestinalis ENSCING00000002175 51511 Ciona savignyi ENSCSAVG00000009964
9361 Dasypus novemcinctus ENSDNOG00000016582 10020 Dipodomys ordii ENSDORG00000002061
9796 Equus caballus ENSECAG00000018546 69293 Gasterosteus aculeatus ENSGACG00000013629
9031 Gallus gallus ENSGALG00000007324 7897 Latimeria chalumnae ENSLACG00000014214
30608 Microcebus murinus ENSMICG00000005240 59463 Myotis lucifugus ENSMLUG00000015597
13616 Monodelphis domestica ENSMODG00000015060 7029 Acyrthosiphon pisum 100160742
10224 Saccoglossus kowalevskii 100313697 7460 Apis mellifera 100577122
61853 Nomascus leucogenys 100606847 10029 Cricetulus griseus 100772309
143995 Megachile rotundata 100880552 34638 Metaseiulus occidentalis 100907785
9555 Papio anubis 101024518 39432 Saimiri boliviensis 101037700
9685 Felis catus 101095124 9595 Gorilla gorilla 101153691
6087 Hydra magnipapillata 101235318 9669 Mustela putorius furo 101680431
9598 Pan troglodytes 460930 9615 Canis familiaris 488125
7070 Tribolium castaneum 655327 9606 Homo sapiens 7161
28377 Anolis carolinensis ENSACAG00000001622 9358 Choloepus hoffmanni ENSCHOG00000010497
9483 Callithrix jacchus ENSCJAG00000002773 10141 Cavia porcellus ENSCPOG00000010908
9365 Erinaceus europaeus ENSEEUG00000013843 9371 Echinops telfairi ENSETEG00000002299
8049 Gadus morhua ENSGMOG00000000413 9315 Macropus eugenii ENSMEUG00000015480
9103 Meleagris gallopavo ENSMGAG00000001562 9258 Ornithorhynchus anatinus ENSOANG00000013795
9986 Oryctolagus cuniculus ENSOCUG00000016465 8128 Oreochromis niloticus ENSONIG00000019325
9978 Ochotona princeps ENSOPRG00000002855 7757 Petromyzon marinus ENSPMAG00000006924
9601 Pongo abelii ENSPPYG00000001963 13735 Pelodiscus sinensis ENSPSIG00000016009
132908 Pteropus vampyrus ENSPVAG00000009056 43179 Ictidomys tridecemlineatus ENSSTOG00000013771
99883 Tetraodon nigroviridis ENSTNIG00000013774 9478 Tarsius syrichta ENSTSYG00000003709
9739 Tursiops truncatus ENSTTRG00000011638 30538 Vicugna pacos ENSVPAG00000012350
8364 Xenopus tropicalis ENSXETG00000026303 8090 Oryzias latipes ENSORLG00000015665
9813 Procavia capensis ENSPCAG00000005011 42254 Sorex araneus ENSSARG00000012752
9305 Sarcophilus harrisii ENSSHAG00000005668 9823 Sus scrofa ENSSSCG00000025592
37347 Tupaia belangeri ENSTBEG00000004215 59729 Taeniopygia guttata ENSTGUG00000009377
31033 Takifugu rubripes ENSTRUG00000003420 8083 Xiphophorus maculatus ENSXMAG00000016425