Basic Information | |||
Gene ID | ENSRNOG00000019496 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | Stat5a; rCG_35111 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Rattus norvegicus [10116] |
Cross Reference | |||
UniProt | G3V8K7 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSRNOP00000026662 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 472 | 597 | 3.10e-46 | EF-hand domain pair |
ENSRNOP00000026662 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 126 | 3.20e-49 | STAT transcription factor, protein interaction |
ENSRNOP00000026662 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 139 | 332 | 1.10e-64 | STAT transcription factor, all-alpha |
ENSRNOP00000026662 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 333 | 471 | 1.60e-68 | STAT transcription factor, DNA-binding, subdomain |
ENSRNOP00000026662 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 598 | 707 | 7.20e-40 | SH2 domain |
ENSRNOP00000026662 | PANTHER | PTHR11801 | IPR001217 | 2 | 773 | 0.00e-00 | Transcription factor STAT |
ENSRNOP00000026662 | Pfam | PF00017 | IPR000980 | 595 | 669 | 1.00e-10 | SH2 domain |
ENSRNOP00000026662 | Pfam | PF01017 | IPR013800 | 138 | 330 | 9.80e-55 | STAT transcription factor, all-alpha |
ENSRNOP00000026662 | Pfam | PF02864 | IPR013801 | 332 | 583 | 1.20e-98 | STAT transcription factor, DNA-binding |
ENSRNOP00000026662 | Pfam | PF02865 | IPR013799 | 2 | 125 | 2.50e-48 | STAT transcription factor, protein interaction |
ENSRNOP00000026662 | ProSiteProfiles | PS50001 | IPR000980 | 589 | 686 | 0.00e-00 | SH2 domain |
ENSRNOP00000026662 | SMART | SM00252 | IPR000980 | 587 | 688 | 3.80e-08 | SH2 domain |
ENSRNOP00000026662 | SMART | SM00964 | IPR013799 | 2 | 126 | 2.60e-66 | STAT transcription factor, protein interaction |
ENSRNOP00000026662 | SUPERFAMILY | SSF47655 | IPR015988 | 136 | 332 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSRNOP00000026662 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 125 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSRNOP00000026662 | SUPERFAMILY | SSF49417 | IPR008967 | 327 | 584 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSRNOP00000026662 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSRNOP00000026662 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSRNOP00000026662 | PF02865 | 0 | STAT_int | STAT protein, protein interaction domain |
ENSRNOP00000026662 | PF00017 | 6.8e-12 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSRNOP00000026662 | GO:0001553 | biological_process | luteinization |
ENSRNOP00000026662 | GO:0001779 | biological_process | natural killer cell differentiation |
ENSRNOP00000026662 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSRNOP00000026662 | GO:0007259 | biological_process | JAK-STAT cascade |
ENSRNOP00000026662 | GO:0007565 | biological_process | female pregnancy |
ENSRNOP00000026662 | GO:0007595 | biological_process | lactation |
ENSRNOP00000026662 | GO:0019218 | biological_process | regulation of steroid metabolic process |
ENSRNOP00000026662 | GO:0019915 | biological_process | lipid storage |
ENSRNOP00000026662 | GO:0030155 | biological_process | regulation of cell adhesion |
ENSRNOP00000026662 | GO:0030856 | biological_process | regulation of epithelial cell differentiation |
ENSRNOP00000026662 | GO:0038161 | biological_process | prolactin signaling pathway |
ENSRNOP00000026662 | GO:0040018 | biological_process | positive regulation of multicellular organism growth |
ENSRNOP00000026662 | GO:0042104 | biological_process | positive regulation of activated T cell proliferation |
ENSRNOP00000026662 | GO:0043029 | biological_process | T cell homeostasis |
ENSRNOP00000026662 | GO:0043066 | biological_process | negative regulation of apoptotic process |
ENSRNOP00000026662 | GO:0045086 | biological_process | positive regulation of interleukin-2 biosynthetic process |
ENSRNOP00000026662 | GO:0045579 | biological_process | positive regulation of B cell differentiation |
ENSRNOP00000026662 | GO:0045647 | biological_process | negative regulation of erythrocyte differentiation |
ENSRNOP00000026662 | GO:0045931 | biological_process | positive regulation of mitotic cell cycle |
ENSRNOP00000026662 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSRNOP00000026662 | GO:0046543 | biological_process | development of secondary female sexual characteristics |
ENSRNOP00000026662 | GO:0050729 | biological_process | positive regulation of inflammatory response |
ENSRNOP00000026662 | GO:0005634 | cellular_component | nucleus |
ENSRNOP00000026662 | GO:0005737 | cellular_component | cytoplasm |
ENSRNOP00000026662 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSRNOP00000026662 | GO:0004871 | molecular_function | signal transducer activity |
ENSRNOP00000026662 | GO:0005509 | molecular_function | calcium ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9598 | Pan troglodytes | 454681 | 9544 | Macaca mulatta | 574129 |
10020 | Dipodomys ordii | ENSDORG00000000303 | 9685 | Felis catus | ENSFCAG00000002153 |
9813 | Procavia capensis | ENSPCAG00000010107 | 10029 | Cricetulus griseus | 100755571 |
34638 | Metaseiulus occidentalis | 100907258 | 30611 | Otolemur garnettii | 100958999 |
9597 | Pan paniscus | 100988550 | 9555 | Papio anubis | 100998364 |
9669 | Mustela putorius furo | 101691575 | 59463 | Myotis lucifugus | 102423996 |
9913 | Bos taurus | ENSBTAG00000009496 | 9483 | Callithrix jacchus | ENSCJAG00000000426 |
9365 | Erinaceus europaeus | ENSEEUG00000003642 | 9371 | Echinops telfairi | ENSETEG00000008535 |
9785 | Loxodonta africana | ENSLAFG00000014055 | 9315 | Macropus eugenii | ENSMEUG00000006640 |
42254 | Sorex araneus | ENSSARG00000014229 | 9739 | Tursiops truncatus | ENSTTRG00000007155 |
8083 | Xiphophorus maculatus | ENSXMAG00000005165 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000006713 |
Paralogs | |||
25126 |