Basic Information
Gene ID ENSSTOG00000020985
Gene Name SMAD7
Full Name Uncharacterized protein
Organism Ictidomys tridecemlineatus [43179]

Cross Reference
UniProt I3MU52 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSTOP00000015647 Gene3D G3DSA:3.90.520.10 IPR013019 1 27 3.30e-52 MAD homology, MH1
ENSSTOP00000015647 Gene3D G3DSA:3.90.520.10 IPR013019 91 214 3.30e-52 MAD homology, MH1
ENSSTOP00000015647 PANTHER PTHR13703 IPR013790 1 247 0.00e-00 Dwarfin
ENSSTOP00000015647 Pfam PF03165 IPR003619 93 202 8.30e-31 MAD homology 1, Dwarfin-type
ENSSTOP00000015647 ProSiteProfiles PS51075 IPR013019 64 207 0.00e-00 MAD homology, MH1
ENSSTOP00000015647 SMART SM00523 IPR003619 87 205 5.50e-54 MAD homology 1, Dwarfin-type
ENSSTOP00000015647 SUPERFAMILY SSF56366 IPR013019 11 27 0.00e-00 MAD homology, MH1
ENSSTOP00000015647 SUPERFAMILY SSF56366 IPR013019 91 202 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSTOP00000015647 PF03165 5.6e-31 MH1 MH1 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSTOP00000015647 GO:0001657 biological_process ureteric bud development
ENSSTOP00000015647 GO:0006351 biological_process transcription, DNA-templated
ENSSTOP00000015647 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSSTOP00000015647 GO:0030512 biological_process negative regulation of transforming growth factor beta receptor signaling pathway
ENSSTOP00000015647 GO:0030514 biological_process negative regulation of BMP signaling pathway
ENSSTOP00000015647 GO:0034616 biological_process response to laminar fluid shear stress
ENSSTOP00000015647 GO:0060394 biological_process negative regulation of pathway-restricted SMAD protein phosphorylation
ENSSTOP00000015647 GO:0005634 cellular_component nucleus
ENSSTOP00000015647 GO:0005667 cellular_component transcription factor complex
ENSSTOP00000015647 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSTOP00000015647 GO:0030617 molecular_function transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ENSSTOP00000015647 GO:0031625 molecular_function ubiquitin protein ligase binding
ENSSTOP00000015647 GO:0034713 molecular_function type I transforming growth factor beta receptor binding
ENSSTOP00000015647 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSSTOP00000015647 GO:0046872 molecular_function metal ion binding
ENSSTOP00000015647 GO:0070411 molecular_function I-SMAD binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9601 Pongo abelii 100460706 9823 Sus scrofa 100521305
39432 Saimiri boliviensis 101039142 8090 Oryzias latipes 101165328
9669 Mustela putorius furo 101689895 7897 Latimeria chalumnae 102346848
59463 Myotis lucifugus 102427200 10090 Mus musculus 17131
9598 Pan troglodytes 455411 10116 Rattus norvegicus 81516
9646 Ailuropoda melanoleuca ENSAMEG00000006739 9615 Canis familiaris ENSCAFG00000019069
7955 Danio rerio ENSDARG00000016858 9796 Equus caballus ENSECAG00000020583
9371 Echinops telfairi ENSETEG00000001041 9685 Felis catus ENSFCAG00000025462
69293 Gasterosteus aculeatus ENSGACG00000016510 9595 Gorilla gorilla ENSGGOG00000010554
8049 Gadus morhua ENSGMOG00000003441 9315 Macropus eugenii ENSMEUG00000011322
30608 Microcebus murinus ENSMICG00000001332 13616 Monodelphis domestica ENSMODG00000003475
61853 Nomascus leucogenys ENSNLEG00000011529 9258 Ornithorhynchus anatinus ENSOANG00000007611
8128 Oreochromis niloticus ENSONIG00000007747 132908 Pteropus vampyrus ENSPVAG00000001966
42254 Sorex araneus ENSSARG00000004025 9555 Papio anubis 101009976
13735 Pelodiscus sinensis 102456346 9606 Homo sapiens 4092
9785 Loxodonta africana ENSLAFG00000008013 9813 Procavia capensis ENSPCAG00000015115
59729 Taeniopygia guttata ENSTGUG00000000034 99883 Tetraodon nigroviridis ENSTNIG00000018764
31033 Takifugu rubripes ENSTRUG00000010212 9739 Tursiops truncatus ENSTTRG00000004362
8364 Xenopus tropicalis ENSXETG00000020317