Basic Information
Gene ID ENSTNIG00000002015
Gene Name TFAP4 (1 of 3)
Full Name Uncharacterized protein
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3C857 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000004429 Gene3D G3DSA:4.10.280.10 IPR011598 49 120 7.90e-19 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTNIP00000004429 Pfam PF00010 IPR011598 49 99 1.30e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTNIP00000004429 ProSiteProfiles PS50888 IPR011598 48 99 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTNIP00000004429 SMART SM00353 IPR011598 54 105 2.30e-18 Myc-type, basic helix-loop-helix (bHLH) domain
ENSTNIP00000004429 SUPERFAMILY SSF47459 IPR011598 42 115 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000004429 PF00010 1.3e-16 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000004429 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSTNIP00000004429 GO:0006461 biological_process protein complex assembly
ENSTNIP00000004429 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ENSTNIP00000004429 GO:0008285 biological_process negative regulation of cell proliferation
ENSTNIP00000004429 GO:0043065 biological_process positive regulation of apoptotic process
ENSTNIP00000004429 GO:0043066 biological_process negative regulation of apoptotic process
ENSTNIP00000004429 GO:0043392 biological_process negative regulation of DNA binding
ENSTNIP00000004429 GO:0043922 biological_process negative regulation by host of viral transcription
ENSTNIP00000004429 GO:0043923 biological_process positive regulation by host of viral transcription
ENSTNIP00000004429 GO:0045736 biological_process negative regulation of cyclin-dependent protein serine/threonine kinase activity
ENSTNIP00000004429 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSTNIP00000004429 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSTNIP00000004429 GO:0071157 biological_process negative regulation of cell cycle arrest
ENSTNIP00000004429 GO:0071549 biological_process cellular response to dexamethasone stimulus
ENSTNIP00000004429 GO:2001269 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
ENSTNIP00000004429 GO:0005634 cellular_component nucleus
ENSTNIP00000004429 GO:0017053 cellular_component transcriptional repressor complex
ENSTNIP00000004429 GO:0000978 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding
ENSTNIP00000004429 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSTNIP00000004429 GO:0003677 molecular_function DNA binding
ENSTNIP00000004429 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ENSTNIP00000004429 GO:0003713 molecular_function transcription coactivator activity
ENSTNIP00000004429 GO:0005515 molecular_function protein binding
ENSTNIP00000004429 GO:0042803 molecular_function protein homodimerization activity
ENSTNIP00000004429 GO:0042826 molecular_function histone deacetylase binding
ENSTNIP00000004429 GO:0043565 molecular_function sequence-specific DNA binding
ENSTNIP00000004429 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSTNIP00000004429 GO:0046982 molecular_function protein heterodimerization activity
ENSTNIP00000004429 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
400682 Amphimedon queenslandica 100635737 7668 Strongylocentrotus purpuratus 578637
8049 Gadus morhua ENSGMOG00000015232 69293 Gasterosteus aculeatus ENSGACG00000018768
8090 Oryzias latipes ENSORLG00000015050 31033 Takifugu rubripes ENSTRUG00000013344
8083 Xiphophorus maculatus ENSXMAG00000011968

Paralogs
ENSTNIG00000014095