Basic Information
Gene ID ENSTNIG00000015103
Gene Name STAT6
Full Name Signal transducer and activator of transcription
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3DCB4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000018158 Gene3D G3DSA:1.10.238.10 IPR011992 438 562 7.50e-39 EF-hand domain pair
ENSTNIP00000018158 Gene3D G3DSA:1.10.532.10 IPR013799 1 122 1.10e-23 STAT transcription factor, protein interaction
ENSTNIP00000018158 Gene3D G3DSA:1.20.1050.20 IPR013800 140 301 7.90e-24 STAT transcription factor, all-alpha
ENSTNIP00000018158 Gene3D G3DSA:2.60.40.630 IPR012345 303 437 9.90e-42 STAT transcription factor, DNA-binding, subdomain
ENSTNIP00000018158 Gene3D G3DSA:3.30.505.10 IPR000980 563 670 2.10e-34 SH2 domain
ENSTNIP00000018158 PANTHER PTHR11801 IPR001217 2 752 0.00e-00 Transcription factor STAT
ENSTNIP00000018158 Pfam PF00017 IPR000980 559 636 2.60e-07 SH2 domain
ENSTNIP00000018158 Pfam PF01017 IPR013800 140 300 1.20e-11 STAT transcription factor, all-alpha
ENSTNIP00000018158 Pfam PF02864 IPR013801 302 548 1.10e-67 STAT transcription factor, DNA-binding
ENSTNIP00000018158 Pfam PF02865 IPR013799 2 122 1.30e-31 STAT transcription factor, protein interaction
ENSTNIP00000018158 ProSiteProfiles PS50001 IPR000980 538 654 0.00e-00 SH2 domain
ENSTNIP00000018158 SMART SM00252 IPR000980 556 643 7.60e-05 SH2 domain
ENSTNIP00000018158 SMART SM00964 IPR013799 2 123 1.70e-39 STAT transcription factor, protein interaction
ENSTNIP00000018158 SUPERFAMILY SSF47655 IPR015988 132 302 0.00e-00 STAT transcription factor, coiled coil
ENSTNIP00000018158 SUPERFAMILY SSF48092 IPR013799 1 122 0.00e-00 STAT transcription factor, protein interaction
ENSTNIP00000018158 SUPERFAMILY SSF49417 IPR008967 294 549 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000018158 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSTNIP00000018158 PF02865 1.3e-31 STAT_int STAT protein, protein interaction domain
ENSTNIP00000018158 PF01017 1.2e-11 STAT_alpha STAT protein, all-alpha domain
ENSTNIP00000018158 PF00017 9.8e-08 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000018158 GO:0001553 biological_process luteinization
ENSTNIP00000018158 GO:0001779 biological_process natural killer cell differentiation
ENSTNIP00000018158 GO:0006351 biological_process transcription, DNA-templated
ENSTNIP00000018158 GO:0007259 biological_process JAK-STAT cascade
ENSTNIP00000018158 GO:0007565 biological_process female pregnancy
ENSTNIP00000018158 GO:0007595 biological_process lactation
ENSTNIP00000018158 GO:0019218 biological_process regulation of steroid metabolic process
ENSTNIP00000018158 GO:0019915 biological_process lipid storage
ENSTNIP00000018158 GO:0030155 biological_process regulation of cell adhesion
ENSTNIP00000018158 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSTNIP00000018158 GO:0038161 biological_process prolactin signaling pathway
ENSTNIP00000018158 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSTNIP00000018158 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSTNIP00000018158 GO:0043029 biological_process T cell homeostasis
ENSTNIP00000018158 GO:0043066 biological_process negative regulation of apoptotic process
ENSTNIP00000018158 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSTNIP00000018158 GO:0045579 biological_process positive regulation of B cell differentiation
ENSTNIP00000018158 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSTNIP00000018158 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSTNIP00000018158 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSTNIP00000018158 GO:0046543 biological_process development of secondary female sexual characteristics
ENSTNIP00000018158 GO:0050729 biological_process positive regulation of inflammatory response
ENSTNIP00000018158 GO:0005634 cellular_component nucleus
ENSTNIP00000018158 GO:0005737 cellular_component cytoplasm
ENSTNIP00000018158 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSTNIP00000018158 GO:0004871 molecular_function signal transducer activity
ENSTNIP00000018158 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100704348 31033 Takifugu rubripes 101065277
28377 Anolis carolinensis ENSACAG00000009680 9483 Callithrix jacchus ENSCJAG00000010327
69293 Gasterosteus aculeatus ENSGACG00000008477 8049 Gadus morhua ENSGMOG00000008275
13616 Monodelphis domestica ENSMODG00000019411 9978 Ochotona princeps ENSOPRG00000013409
9601 Pongo abelii ENSPPYG00000004680 37347 Tupaia belangeri ENSTBEG00000013664
59729 Taeniopygia guttata ENSTGUG00000015716 8364 Xenopus tropicalis ENSXETG00000004431
8083 Xiphophorus maculatus ENSXMAG00000010611