Basic Information
Gene ID ENSXETG00000007642
Gene Name stat3.1
Full Name Signal transducer and activator of transcription
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F6Q0N5 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000016634 Gene3D G3DSA:1.10.238.10 IPR011992 120 241 6.90e-59 EF-hand domain pair
ENSXETP00000016634 Gene3D G3DSA:1.10.238.10 IPR011992 890 1008 5.60e-53 EF-hand domain pair
ENSXETP00000016634 Gene3D G3DSA:1.10.532.10 IPR013799 470 589 2.80e-45 STAT transcription factor, protein interaction
ENSXETP00000016634 Gene3D G3DSA:1.20.1050.20 IPR013800 608 788 4.90e-68 STAT transcription factor, all-alpha
ENSXETP00000016634 Gene3D G3DSA:2.60.40.630 IPR012345 29 119 4.00e-26 STAT transcription factor, DNA-binding, subdomain
ENSXETP00000016634 Gene3D G3DSA:2.60.40.630 IPR012345 789 878 1.00e-22 STAT transcription factor, DNA-binding, subdomain
ENSXETP00000016634 Gene3D G3DSA:3.30.505.10 IPR000980 1052 1140 7.40e-25 SH2 domain
ENSXETP00000016634 Gene3D G3DSA:3.30.505.10 IPR000980 242 354 6.90e-49 SH2 domain
ENSXETP00000016634 PANTHER PTHR11801 IPR001217 471 1171 0.00e-00 Transcription factor STAT
ENSXETP00000016634 Pfam PF00017 IPR000980 237 327 4.30e-13 SH2 domain
ENSXETP00000016634 Pfam PF01017 IPR013800 608 787 2.50e-57 STAT transcription factor, all-alpha
ENSXETP00000016634 Pfam PF02864 IPR013801 28 227 6.70e-82 STAT transcription factor, DNA-binding
ENSXETP00000016634 Pfam PF02864 IPR013801 878 998 1.00e-57 STAT transcription factor, DNA-binding
ENSXETP00000016634 Pfam PF02865 IPR013799 471 589 1.60e-41 STAT transcription factor, protein interaction
ENSXETP00000016634 ProSiteProfiles PS50001 IPR000980 233 323 0.00e-00 SH2 domain
ENSXETP00000016634 SMART SM00252 IPR000980 235 316 1.00e-03 SH2 domain
ENSXETP00000016634 SMART SM00964 IPR013799 471 591 4.50e-63 STAT transcription factor, protein interaction
ENSXETP00000016634 SUPERFAMILY SSF47655 IPR015988 605 787 0.00e-00 STAT transcription factor, coiled coil
ENSXETP00000016634 SUPERFAMILY SSF48092 IPR013799 470 589 0.00e-00 STAT transcription factor, protein interaction
ENSXETP00000016634 SUPERFAMILY SSF49417 IPR008967 29 228 0.00e-00 p53-like transcription factor, DNA-binding
ENSXETP00000016634 SUPERFAMILY SSF49417 IPR008967 788 999 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000016634 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSXETP00000016634 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSXETP00000016634 PF02865 1.6e-41 STAT_int STAT protein, protein interaction domain
ENSXETP00000016634 PF00017 1e-13 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000016634 GO:0001659 biological_process temperature homeostasis
ENSXETP00000016634 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSXETP00000016634 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSXETP00000016634 GO:0019953 biological_process sexual reproduction
ENSXETP00000016634 GO:0042593 biological_process glucose homeostasis
ENSXETP00000016634 GO:0042755 biological_process eating behavior
ENSXETP00000016634 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSXETP00000016634 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSXETP00000016634 GO:0005634 cellular_component nucleus
ENSXETP00000016634 GO:0005737 cellular_component cytoplasm
ENSXETP00000016634 GO:0005886 cellular_component plasma membrane
ENSXETP00000016634 GO:0003677 molecular_function DNA binding
ENSXETP00000016634 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSXETP00000016634 GO:0004871 molecular_function signal transducer activity
ENSXETP00000016634 GO:0005509 molecular_function calcium ion binding
ENSXETP00000016634 GO:0019901 molecular_function protein kinase binding
ENSXETP00000016634 GO:0043565 molecular_function sequence-specific DNA binding
ENSXETP00000016634 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus ENSCJAG00000000409 9785 Loxodonta africana ENSLAFG00000014062
9978 Ochotona princeps ENSOPRG00000008362 9986 Oryctolagus cuniculus 100348778
10029 Cricetulus griseus 100755865 9597 Pan paniscus 100987766
9555 Papio anubis 100998929 39432 Saimiri boliviensis 101049662
31033 Takifugu rubripes 101070968 9685 Felis catus 101095698
8083 Xiphophorus maculatus 102226045 9615 Canis familiaris 490967
28377 Anolis carolinensis ENSACAG00000017940 9646 Ailuropoda melanoleuca ENSAMEG00000006266
9358 Choloepus hoffmanni ENSCHOG00000009349 10141 Cavia porcellus ENSCPOG00000007939
9361 Dasypus novemcinctus ENSDNOG00000001471 10020 Dipodomys ordii ENSDORG00000000308
9796 Equus caballus ENSECAG00000016439 69293 Gasterosteus aculeatus ENSGACG00000008607
9595 Gorilla gorilla ENSGGOG00000017110 8049 Gadus morhua ENSGMOG00000014955
7897 Latimeria chalumnae ENSLACG00000012019 9315 Macropus eugenii ENSMEUG00000006663
9103 Meleagris gallopavo ENSMGAG00000003545 30608 Microcebus murinus ENSMICG00000012015
59463 Myotis lucifugus ENSMLUG00000017449 9544 Macaca mulatta ENSMMUG00000010707
13616 Monodelphis domestica ENSMODG00000028212 9669 Mustela putorius furo ENSMPUG00000010509
30611 Otolemur garnettii ENSOGAG00000001517 8128 Oreochromis niloticus ENSONIG00000001148
8090 Oryzias latipes ENSORLG00000004061 9813 Procavia capensis ENSPCAG00000010265
9601 Pongo abelii ENSPPYG00000008392 13735 Pelodiscus sinensis ENSPSIG00000015868
132908 Pteropus vampyrus ENSPVAG00000003885 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000014833 43179 Ictidomys tridecemlineatus ENSSTOG00000006741
59729 Taeniopygia guttata ENSTGUG00000002600 9478 Tarsius syrichta ENSTSYG00000012448
9739 Tursiops truncatus ENSTTRG00000007163